VDAC2_HUMAN
Evidence for PS localization
Functions
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules . The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV . The open state has a weak anion selectivity whereas the closed state is cation-selective . Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (PubMed). Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in VDAC2_HUMAN |
|---|---|---|---|---|
| GO:0046872 | metal ion binding | 26.5823 | 4 | no |
| GO:0003723 | RNA binding | 22.7848 | 4 | no |
| GO:0008509 | anion transmembrane transporter activity | 6.9620 | 4 | yes |
| GO:0015267 | channel activity | 5.6962 | 4 | yes |
| GO:0005216 | ion channel activity | 4.4304 | 4 | yes |
| GO:0022836 | gated channel activity | 3.7975 | 5 | yes |
| GO:0005244 | voltage-gated ion channel activity | 3.1646 | 4 | yes |
| GO:0015103 | inorganic anion transmembrane transporter activity | 3.1646 | 4 | yes |
| GO:0022829 | wide pore channel activity | 3.1646 | 5 | yes |
| GO:0022832 | voltage-gated channel activity | 3.1646 | 6 | yes |
| GO:0015288 | porin activity | 2.5316 | 6 | yes |
| GO:0005253 | anion channel activity | 1.8987 | 5 | yes |
| GO:0008308 | voltage-gated anion channel activity | 1.8987 | 5 | yes |
| GO:0015485 | cholesterol binding | 1.2658 | 4 | yes |
| GO:0032934 | sterol binding | 1.2658 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in VDAC2_HUMAN |
|---|---|---|---|---|
| GO:0031323 | regulation of cellular metabolic process | 44.3038 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 43.6709 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 41.1392 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 40.5063 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 39.2405 | 4 | no |
| GO:0022607 | cellular component assembly | 38.6076 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 34.8101 | 4 | yes |
| GO:0006996 | organelle organization | 34.1772 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 34.1772 | 4 | yes |
| GO:0010646 | regulation of cell communication | 32.9114 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 32.2785 | 4 | no |
| GO:0008104 | protein localization | 31.0127 | 4 | no |
| GO:0009966 | regulation of signal transduction | 30.3797 | 4 | yes |
| GO:0010468 | regulation of gene expression | 29.1139 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 29.1139 | 5 | no |
| GO:0071702 | organic substance transport | 28.4810 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 26.5823 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.9494 | 4 | no |
| GO:0051049 | regulation of transport | 25.3165 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 25.3165 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.3165 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.3165 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.6835 | 5 | no |
| GO:0010941 | regulation of cell death | 24.0506 | 4 | yes |
| GO:0065003 | protein-containing complex assembly | 24.0506 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 24.0506 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.0506 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 24.0506 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 23.4177 | 5 | no |
| GO:0071310 | cellular response to organic substance | 23.4177 | 4 | no |
| GO:0009894 | regulation of catabolic process | 22.1519 | 4 | no |
| GO:0010243 | response to organonitrogen compound | 22.1519 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 21.5190 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 21.5190 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 21.5190 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 20.8861 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 20.2532 | 6 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.2532 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.2532 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.2532 | 6 | no |
| GO:0006811 | ion transport | 18.3544 | 4 | yes |
| GO:0010648 | negative regulation of cell communication | 17.7215 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 17.7215 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 17.0886 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 16.4557 | 5 | yes |
| GO:0060548 | negative regulation of cell death | 15.8228 | 5 | yes |
| GO:0043069 | negative regulation of programmed cell death | 14.5570 | 6 | yes |
| GO:0043066 | negative regulation of apoptotic process | 13.2911 | 7 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 13.2911 | 4 | yes |
| GO:0007005 | mitochondrion organization | 11.3924 | 5 | yes |
| GO:0061024 | membrane organization | 11.3924 | 4 | yes |
| GO:0006820 | anion transport | 8.2278 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 8.2278 | 5 | yes |
| GO:2001233 | regulation of apoptotic signaling pathway | 8.2278 | 5 | yes |
| GO:1902532 | negative regulation of intracellular signal transduction | 6.9620 | 6 | yes |
| GO:0007006 | mitochondrial membrane organization | 6.3291 | 5 | yes |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 6.3291 | 6 | yes |
| GO:0043254 | regulation of protein-containing complex assembly | 5.6962 | 5 | yes |
| GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 5.0633 | 6 | yes |
| GO:0032271 | regulation of protein polymerization | 4.4304 | 6 | yes |
| GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 3.7975 | 7 | yes |
| GO:0008637 | apoptotic mitochondrial changes | 3.1646 | 6 | yes |
| GO:0046902 | regulation of mitochondrial membrane permeability | 3.1646 | 4 | yes |
| GO:0031333 | negative regulation of protein-containing complex assembly | 1.8987 | 6 | yes |
| GO:0032272 | negative regulation of protein polymerization | 1.2658 | 7 | yes |
| GO:0035794 | positive regulation of mitochondrial membrane permeability | 1.2658 | 5 | yes |
| GO:0097345 | mitochondrial outer membrane permeabilization | 1.2658 | 7 | yes |
| GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process | 1.2658 | 5 | yes |
| GO:1902110 | positive regulation of mitochondrial membrane permeability involved in apoptotic process | 1.2658 | 6 | yes |
| GO:1902686 | mitochondrial outer membrane permeabilization involved in programmed cell death | 1.2658 | 6 | yes |
| GO:1905710 | positive regulation of membrane permeability | 1.2658 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in VDAC2_HUMAN |
|---|---|---|---|---|
| DOID:574 | peripheral nervous system disease | 3.1646 | 3 | no |
| DOID:870 | neuropathy | 3.1646 | 4 | no |
| DOID:10595 | Charcot-Marie-Tooth disease | 2.5316 | 6 | no |
| DOID:440 | neuromuscular disease | 2.5316 | 5 | no |
| DOID:0050155 | sensory system disease | 1.2658 | 3 | no |
| DOID:0050542 | Charcot-Marie-Tooth disease type X | 1.2658 | 7 | no |
| DOID:0050563 | nonsyndromic deafness | 1.2658 | 5 | no |
| DOID:2742 | auditory system disease | 1.2658 | 4 | no |
| DOID:700 | mitochondrial metabolism disease | 1.2658 | 3 | no |
| DOID:0050700 | cardiomyopathy | 1.2658 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.2658 | 5 | no |
| DOID:114 | heart disease | 1.2658 | 3 | no |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.2658 | 7 | no |
| DOID:1289 | neurodegenerative disease | 1.2658 | 4 | no |
| DOID:331 | central nervous system disease | 1.2658 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PRKN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBXL6_HUMAN | [view interactions] | Low throughput | no | no |
| NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAK_HUMAN | [view interactions] | Low throughput | no | no |
| F162A_HUMAN | [view interactions] | Low throughput | no | yes |
| F16P1_HUMAN | [view interactions] | Low throughput | no | no |
| VDAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| BET1_HUMAN | [view interactions] | High throughput | no | no |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| NIPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD4_HUMAN | [view interactions] | High throughput | no | no |
| ZN782_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| DYH8_HUMAN | [view interactions] | High throughput | no | no |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| DJC10_HUMAN | [view interactions] | High throughput | no | yes |
| SUMO3_HUMAN | [view interactions] | High throughput | no | yes |
| GANAB_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEK11_HUMAN | [view interactions] | High throughput | no | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| PHF8_HUMAN | [view interactions] | High throughput | no | yes |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| RCBT1_HUMAN | [view interactions] | High throughput | no | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STON2_HUMAN | [view interactions] | High throughput | no | yes |
| ADRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALU_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD3_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| POTEF_HUMAN | [view interactions] | High throughput | no | no |
| ARF5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFC5_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| B3AT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| LTOR5_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TOM70_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| RRAGC_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HXK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| LTOR3_HUMAN | [view interactions] | High throughput | no | yes |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| ABHD4_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR2_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| RRAGA_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| KDM2A_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA3_HUMAN | [view interactions] | High throughput | no | no |
| AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
| DAPK2_HUMAN | [view interactions] | High throughput | no | no |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| SNAI1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| PKHA2_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| CTCF_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| S15A3_HUMAN | [view interactions] | High throughput | no | yes |
| UN93B_HUMAN | [view interactions] | High throughput | no | yes |
| NOD2_HUMAN | [view interactions] | High throughput | no | yes |
| TAP1_HUMAN | [view interactions] | High throughput | no | yes |
| PTMA_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERD21_HUMAN | [view interactions] | High throughput | no | yes |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| INSI2_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| PAGE4_HUMAN | [view interactions] | High throughput | no | no |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| AGRE5_HUMAN | [view interactions] | High throughput | no | no |
| GLR_HUMAN | [view interactions] | High throughput | no | no |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| KCNA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NB5R3_HUMAN | [view interactions] | High throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPRNG_HUMAN | [view interactions] | High throughput | no | yes |
| NED4L_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VATH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SFXN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPV17_HUMAN | [view interactions] | High throughput | no | no |
| SCP2_HUMAN | [view interactions] | High throughput | no | no |
| ZFR_HUMAN | [view interactions] | High throughput | no | yes |
| SUGP1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DUX4C_HUMAN | [view interactions] | High throughput | no | no |
| SND1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN454_HUMAN | [view interactions] | High throughput | no | no |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| CLN3_HUMAN | [view interactions] | High throughput | no | no |
| THOC6_HUMAN | [view interactions] | High throughput | no | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| VATF_HUMAN | [view interactions] | High throughput | no | yes |
| S38A9_HUMAN | [view interactions] | High throughput | no | yes |
| TRAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S38A1_HUMAN | [view interactions] | High throughput | no | yes |
| UT14A_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| THIM_HUMAN | [view interactions] | High throughput | no | yes |
| HEM6_HUMAN | [view interactions] | High throughput | no | no |
| ATPA_HUMAN | [view interactions] | High throughput | no | yes |
| HEMH_HUMAN | [view interactions] | High throughput | no | yes |
| ATPB_HUMAN | [view interactions] | High throughput | no | yes |
| PPOX_HUMAN | [view interactions] | High throughput | no | no |
| ATPD_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP5I_HUMAN | [view interactions] | High throughput | no | yes |
| RMD3_HUMAN | [view interactions] | High throughput | no | yes |
| ATPO_HUMAN | [view interactions] | High throughput | no | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| VA0D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| PAR6B_HUMAN | [view interactions] | High throughput | no | no |
| CISD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM109_HUMAN | [view interactions] | High throughput | no | yes |
| CISD2_HUMAN | [view interactions] | High throughput | no | yes |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| GPX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MTX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| TMED2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGT1_HUMAN | [view interactions] | High throughput | no | yes |
| TPC11_HUMAN | [view interactions] | High throughput | no | no |
| NDUAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUA8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC5_HUMAN | [view interactions] | High throughput | no | yes |
| NDUA9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSCL2_HUMAN | [view interactions] | High throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOT1B_HUMAN | [view interactions] | High throughput | no | yes |
| RER1_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGPL1_HUMAN | [view interactions] | High throughput | no | yes |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DENR_HUMAN | [view interactions] | High throughput | no | yes |
| SSRG_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| STX12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| NMES1_HUMAN | [view interactions] | High throughput | no | no |
| TSPO_HUMAN | [view interactions] | High throughput | no | yes |
| MET14_HUMAN | [view interactions] | High throughput | no | yes |
| QCR8_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| MRP1_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| MRP3_HUMAN | [view interactions] | High throughput | no | no |
| CAV2_HUMAN | [view interactions] | High throughput | no | no |
| ACADM_HUMAN | [view interactions] | High throughput | no | yes |
| NCBP3_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NCBP2_HUMAN | [view interactions] | High throughput | no | yes |
| AT1A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC11_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1A3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATPG_HUMAN | [view interactions] | High throughput | no | yes |
| AT5F1_HUMAN | [view interactions] | High throughput | no | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COQ2_HUMAN | [view interactions] | High throughput | no | yes |
| COX41_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JAGN1_HUMAN | [view interactions] | High throughput | no | no |
| SOAT1_HUMAN | [view interactions] | High throughput | no | no |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC42_HUMAN | [view interactions] | High throughput | no | yes |
| COX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRP2_HUMAN | [view interactions] | High throughput | no | no |
| NDUB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHCH9_HUMAN | [view interactions] | High throughput | no | no |
| NDUS4_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VDAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| DDX21_HUMAN | [view interactions] | High throughput | no | yes |
| TMX1_HUMAN | [view interactions] | High throughput | no | no |
| PZP_HUMAN | [view interactions] | High throughput | no | no |
| QCR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRC2_HUMAN | [view interactions] | High throughput | no | no |
| P4HA1_HUMAN | [view interactions] | High throughput | no | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| AASS_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DRD2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYOF_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT2_HUMAN | [view interactions] | High throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLXB2_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P4HA2_HUMAN | [view interactions] | High throughput | no | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| MEST_HUMAN | [view interactions] | High throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF2B1_HUMAN | [view interactions] | High throughput | no | no |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED23_HUMAN | [view interactions] | High throughput | no | no |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EMC1_HUMAN | [view interactions] | High throughput | no | yes |
| MOGS_HUMAN | [view interactions] | High throughput | no | yes |
| TXD16_HUMAN | [view interactions] | High throughput | no | yes |
| MCLN1_HUMAN | [view interactions] | High throughput | no | yes |
| FXRD2_HUMAN | [view interactions] | High throughput | no | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIPK4_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MCAT_HUMAN | [view interactions] | High throughput | no | yes |
| PAK6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCAD2_HUMAN | [view interactions] | High throughput | no | yes |
| KLF16_HUMAN | [view interactions] | High throughput | no | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| PREB_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| SERC3_HUMAN | [view interactions] | High throughput | no | yes |
| ARL8B_HUMAN | [view interactions] | High throughput | no | yes |
| NEP_HUMAN | [view interactions] | High throughput | no | no |
| GALT2_HUMAN | [view interactions] | High throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BST2_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| PKHG5_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| TTYH3_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL9_HUMAN | [view interactions] | High throughput | no | no |
| DDR1_HUMAN | [view interactions] | High throughput | no | yes |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNQ1_HUMAN | [view interactions] | High throughput | no | yes |
| ITAV_HUMAN | [view interactions] | High throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TM205_HUMAN | [view interactions] | High throughput | no | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| TOM5_HUMAN | [view interactions] | High throughput | no | yes |
| MYPC3_HUMAN | [view interactions] | High throughput | no | no |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD177_HUMAN | [view interactions] | High throughput | no | no |
| ATPK_HUMAN | [view interactions] | High throughput | no | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| SCPDL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSMR_HUMAN | [view interactions] | High throughput | no | yes |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNDD3_HUMAN | [view interactions] | High throughput | no | no |
| AN34C_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| ODBA_HUMAN | [view interactions] | High throughput | no | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COX6C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CX7A2_HUMAN | [view interactions] | High throughput | no | no |
| DHRS2_HUMAN | [view interactions] | High throughput | no | no |
| COX7R_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CATD_HUMAN | [view interactions] | High throughput | no | yes |
| COX7C_HUMAN | [view interactions] | High throughput | no | yes |
| GRN_HUMAN | [view interactions] | High throughput | no | no |
| COX8A_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NIPS2_HUMAN | [view interactions] | High throughput | no | yes |
| NDUV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ML12A_HUMAN | [view interactions] | High throughput | no | no |
| PEX1_HUMAN | [view interactions] | High throughput | no | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ICAM5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTHY_HUMAN | [view interactions] | High throughput | no | no |
| NDUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRK1_HUMAN | [view interactions] | High throughput | no | no |
| NDUS5_HUMAN | [view interactions] | High throughput | no | yes |
| WFS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLF11_HUMAN | [view interactions] | High throughput | no | no |
| NDUS8_HUMAN | [view interactions] | High throughput | no | yes |
| TPPP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCCB_HUMAN | [view interactions] | High throughput | no | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QCR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF11_HUMAN | [view interactions] | High throughput | no | yes |
| RCAF1_HUMAN | [view interactions] | High throughput | no | yes |
| PHKG2_HUMAN | [view interactions] | High throughput | no | no |
| COA3_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NB5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPID_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RYR2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PPIF_HUMAN | [view interactions] | Computational | no | no |
| ADT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CYC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ADT4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MIRO1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MUL1_HUMAN | [view interactions] | Computational | no | no |
| MAT2B_HUMAN | [view interactions] | Computational | no | yes |
| TM40L_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MPCP_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| UCRI_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PTH2_HUMAN | [view interactions] | Computational | no | yes |
| IDE_HUMAN | [view interactions] | Computational | no | yes |
| STAR_HUMAN | [view interactions] | Computational | no | no |
| TOM22_HUMAN | [view interactions] | Computational | no | yes |