ICAM5_HUMAN
Evidence for PS localization
Functions
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). [View more on UniProt]
Protein features
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 91%
![](/static/images/legend1.gif)
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
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ICAM5_HUMAN has binary interactions with 20 proteins
Isoforms
Interacting regions
Canonical [ICAM5_HUMAN]
Isoform [A0A9L9PXE8] alignment
LOADING 80%
![](/static/images/legend3.gif)
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
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Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in ICAM5_HUMAN |
---|---|---|---|---|
GO:0043169 | cation binding | 23.8095 | 4 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in ICAM5_HUMAN |
---|---|---|---|---|
GO:0048523 | negative regulation of cellular process | 52.3810 | 4 | no |
GO:0010646 | regulation of cell communication | 47.6190 | 4 | no |
GO:0051128 | regulation of cellular component organization | 42.8571 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 42.8571 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 42.8571 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 42.8571 | 4 | no |
GO:0006996 | organelle organization | 42.8571 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 38.0952 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 38.0952 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 38.0952 | 4 | no |
GO:0051049 | regulation of transport | 38.0952 | 4 | no |
GO:0022607 | cellular component assembly | 38.0952 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 33.3333 | 4 | no |
GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
GO:0009966 | regulation of signal transduction | 33.3333 | 4 | no |
GO:0010468 | regulation of gene expression | 33.3333 | 6 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 33.3333 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
GO:0051252 | regulation of RNA metabolic process | 33.3333 | 5 | no |
GO:0009894 | regulation of catabolic process | 33.3333 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 33.3333 | 5 | no |
Disease
No data found.
All partners
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AMBN_HUMAN | [view interactions] | High throughput | no | no |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
AQP3_HUMAN | [view interactions] | High throughput | no | no |
ARMC6_HUMAN | [view interactions] | High throughput | no | yes |
BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CBR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CD14_HUMAN | [view interactions] | High throughput | no | no |
CD248_HUMAN | [view interactions] | High throughput | no | no |
CRLF3_HUMAN | [view interactions] | High throughput | no | yes |
CSF1_HUMAN | [view interactions] | High throughput | no | no |
DHX9_HUMAN | [view interactions] | High throughput | no | yes |
DNSL1_HUMAN | [view interactions] | High throughput | no | yes |
DSN1_HUMAN | [view interactions] | High throughput | no | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F117B_HUMAN | [view interactions] | High throughput | no | no |
FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FBX6_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GGH_HUMAN | [view interactions] | High throughput | no | yes |
GML_HUMAN | [view interactions] | High throughput | no | no |
GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
H3C_HUMAN | [view interactions] | High throughput | no | yes |