Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ICAM5_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ICAM5_HUMAN
GO:0043169 cation binding 23.8095 4 no

Biological process

Term Name % Distance from top the of the tree Annotated in ICAM5_HUMAN
GO:0048523 negative regulation of cellular process 52.3810 4 no
GO:0010646 regulation of cell communication 47.6190 4 no
GO:0051128 regulation of cellular component organization 42.8571 4 yes
GO:0048522 positive regulation of cellular process 42.8571 4 no
GO:0060255 regulation of macromolecule metabolic process 42.8571 4 no
GO:0080090 regulation of primary metabolic process 42.8571 4 no
GO:0006996 organelle organization 42.8571 4 no
GO:0044087 regulation of cellular component biogenesis 38.0952 4 yes
GO:0009893 positive regulation of metabolic process 38.0952 4 no
GO:0031323 regulation of cellular metabolic process 38.0952 4 no
GO:0051049 regulation of transport 38.0952 4 no
GO:0022607 cellular component assembly 38.0952 4 no
GO:0009889 regulation of biosynthetic process 33.3333 4 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0010468 regulation of gene expression 33.3333 6 no
GO:0010556 regulation of macromolecule biosynthetic process 33.3333 5 no
GO:0010604 positive regulation of macromolecule metabolic process 33.3333 5 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 33.3333 5 no
GO:0031325 positive regulation of cellular metabolic process 33.3333 5 no
GO:0031326 regulation of cellular biosynthetic process 33.3333 5 no
GO:0051252 regulation of RNA metabolic process 33.3333 5 no
GO:0009894 regulation of catabolic process 33.3333 4 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0009890 negative regulation of biosynthetic process 28.5714 5 no
GO:0009891 positive regulation of biosynthetic process 28.5714 5 no
GO:0010558 negative regulation of macromolecule biosynthetic process 28.5714 6 no
GO:0031324 negative regulation of cellular metabolic process 28.5714 5 no
GO:0031327 negative regulation of cellular biosynthetic process 28.5714 6 no
GO:0031328 positive regulation of cellular biosynthetic process 28.5714 6 no
GO:0050804 modulation of chemical synaptic transmission 28.5714 5 no
GO:0099177 regulation of trans-synaptic signaling 28.5714 4 no
GO:0009896 positive regulation of catabolic process 28.5714 5 no
GO:0042176 regulation of protein catabolic process 28.5714 5 no
GO:0042981 regulation of apoptotic process 28.5714 5 no
GO:0043067 regulation of programmed cell death 28.5714 4 no
GO:0051247 positive regulation of protein metabolic process 28.5714 6 no
GO:0051130 positive regulation of cellular component organization 23.8095 5 no
GO:0031399 regulation of protein modification process 23.8095 6 no
GO:0034762 regulation of transmembrane transport 23.8095 4 no
GO:0050807 regulation of synapse organization 23.8095 5 yes
GO:0098657 import into cell 23.8095 4 yes
GO:0006355 regulation of DNA-templated transcription 23.8095 7 no
GO:0006357 regulation of transcription by RNA polymerase II 23.8095 8 no
GO:0006508 proteolysis 23.8095 4 no
GO:0008104 protein localization 23.8095 4 no
GO:0009968 negative regulation of signal transduction 23.8095 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 23.8095 6 no
GO:0010648 negative regulation of cell communication 23.8095 5 no
GO:0023057 negative regulation of signaling 23.8095 4 no
GO:0030030 cell projection organization 23.8095 4 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 23.8095 5 no
GO:0048585 negative regulation of response to stimulus 23.8095 4 no
GO:0051050 positive regulation of transport 23.8095 4 no
GO:0051253 negative regulation of RNA metabolic process 23.8095 6 no
GO:0120036 plasma membrane bounded cell projection organization 23.8095 5 no
GO:2001141 regulation of RNA biosynthetic process 23.8095 6 no
GO:0060627 regulation of vesicle-mediated transport 23.8095 4 no
GO:0006915 apoptotic process 23.8095 4 no
GO:0043066 negative regulation of apoptotic process 23.8095 6 no
GO:0043069 negative regulation of programmed cell death 23.8095 5 no
GO:0034330 cell junction organization 23.8095 4 no
GO:0051963 regulation of synapse assembly 14.2857 6 yes
GO:1901888 regulation of cell junction assembly 14.2857 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
PSN2_HUMAN [view entry] [view interactions] Low throughput yes no
ITAL_HUMAN [view interactions] Low throughput no no
HEM1_HUMAN [view interactions] High throughput no yes
AMBN_HUMAN [view interactions] High throughput no no
KLF5_HUMAN [view interactions] High throughput no yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
MT2_HUMAN [view interactions] High throughput no no
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
TADA3_HUMAN [view interactions] High throughput no yes
MYLIP_HUMAN [view interactions] High throughput no no
CRLF3_HUMAN [view interactions] High throughput no yes
REX1B_HUMAN [view interactions] High throughput no no
RNF31_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
CD248_HUMAN [view interactions] High throughput no no
PSF3_HUMAN [view interactions] High throughput no yes
LRC61_HUMAN [view interactions] High throughput no yes
DSN1_HUMAN [view interactions] High throughput no yes
LZTS2_HUMAN [view interactions] High throughput no no
KLH32_HUMAN [view interactions] High throughput no yes
KT222_HUMAN [view interactions] High throughput no no
F117B_HUMAN [view interactions] High throughput no no
H3C_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
LEG1_HUMAN [view interactions] High throughput no yes
ARMC6_HUMAN [view interactions] High throughput no yes
SCOT2_HUMAN [view interactions] High throughput no no
DNSL1_HUMAN [view interactions] High throughput no yes
PRG2_HUMAN [view interactions] High throughput no no
IL5RA_HUMAN [view interactions] High throughput no no
LEG8_HUMAN [view entry] [view interactions] High throughput yes yes
HS12A_HUMAN [view entry] [view interactions] High throughput yes yes
TM2D3_HUMAN [view interactions] High throughput no yes
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes
LY86_HUMAN [view interactions] High throughput no no
LEG3_HUMAN [view interactions] High throughput no yes
SLUR1_HUMAN [view interactions] High throughput no no
PTC1_HUMAN [view entry] [view interactions] High throughput yes yes
HYAL1_HUMAN [view interactions] High throughput no no
NNRD_HUMAN [view interactions] High throughput no yes
AQP3_HUMAN [view interactions] High throughput no no
GGH_HUMAN [view interactions] High throughput no yes
GML_HUMAN [view interactions] High throughput no no
PGFRA_HUMAN [view interactions] High throughput no no
TECT1_HUMAN [view interactions] High throughput no yes
PLPL5_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
EGFR_HUMAN [view interactions] High throughput no no
DHX9_HUMAN [view interactions] High throughput no yes
SHOC2_HUMAN [view interactions] High throughput no yes
PAR6B_HUMAN [view interactions] High throughput no no
SGO2_HUMAN [view interactions] High throughput no no
RMD3_HUMAN [view entry] [view interactions] High throughput yes yes
SART3_HUMAN [view interactions] High throughput no yes
STA5A_HUMAN [view interactions] High throughput no no
T132A_HUMAN [view interactions] High throughput no yes
KI18A_HUMAN [view interactions] High throughput no yes
TZAP_HUMAN [view interactions] High throughput no no
RNH2A_HUMAN [view interactions] High throughput no no
NAF1_HUMAN [view interactions] High throughput no yes
CD14_HUMAN [view interactions] High throughput no no
ILK_HUMAN [view interactions] High throughput no no
CBR1_HUMAN [view entry] [view interactions] High throughput yes yes
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
SORT_HUMAN [view interactions] High throughput no yes
CSF1_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
PTN4_HUMAN [view interactions] High throughput no no
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
PEX5R_HUMAN [view entry] [view interactions] High throughput yes yes