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PSN1_HUMAN

Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Requires the presence of the other members of the gamma-secretase complex for protease activity (PubMed, PubMed, PubMed, PubMed, PubMed). Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (PubMed, PubMed, PubMed, PubMed). Stimulates cell-cell adhesion via its interaction with CDH1; this stabilizes the complexes between CDH1 (E-cadherin) and its interaction partners CTNNB1 (beta-catenin), CTNND1 and JUP (gamma-catenin) (PubMed). Under conditions of apoptosis or calcium influx, cleaves CDH1 (PubMed). This promotes the disassembly of the complexes between CDH1 and CTNND1, JUP and CTNNB1, increases the pool of cytoplasmic CTNNB1, and thereby negatively regulates Wnt signaling (PubMed, PubMed). Required for normal embryonic brain and skeleton development, and for normal angiogenesis . Mediates the proteolytic cleavage of EphB2/CTF1 into EphB2/CTF2 (PubMed, PubMed). The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is therefore involved in calcium homeostasis (PubMed, PubMed). Involved in the regulation of neurite outgrowth (PubMed, PubMed). Is a regulator of presynaptic facilitation, spike transmission and synaptic vesicles replenishment in a process that depends on gamma-secretase activity. It acts through the control of SYT7 presynaptic expression . [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI002184 LIG_PDZ_Class_2 LIG 462 467 -
ELMI003227 MOD_CDK_SPxxK_3 MOD 351 358 -

Molecular function

Term Name % Distance from the top of the tree Annotated in PSN1_HUMAN
GO:0017076 purine nucleotide binding 29.3333 4 no
GO:0032555 purine ribonucleotide binding 28.6667 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.0000 4 no
GO:0046872 metal ion binding 27.3333 4 no
GO:0045296 cadherin binding 12.6667 4 yes
GO:0008324 cation transmembrane transporter activity 12.0000 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 11.3333 4 yes
GO:0046873 metal ion transmembrane transporter activity 8.0000 5 yes
GO:0005216 ion channel activity 6.6667 4 yes
GO:0015267 channel activity 6.6667 4 yes
GO:0005261 cation channel activity 5.3333 5 yes
GO:0015085 calcium ion transmembrane transporter activity 5.3333 6 yes
GO:0005262 calcium channel activity 4.6667 6 yes
GO:0070851 growth factor receptor binding 4.0000 4 yes
GO:0004175 endopeptidase activity 3.3333 4 yes
GO:0051117 ATPase binding 3.3333 4 yes
GO:0004190 aspartic-type endopeptidase activity 2.0000 5 yes
GO:0030165 PDZ domain binding 2.0000 4 yes
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving 2.0000 6 yes
GO:0070001 aspartic-type peptidase activity 2.0000 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PSN1_HUMAN
GO:0048522 positive regulation of cellular process 57.3333 4 yes
GO:0048523 negative regulation of cellular process 44.0000 4 yes
GO:0060255 regulation of macromolecule metabolic process 40.6667 4 yes
GO:0080090 regulation of primary metabolic process 40.6667 4 yes
GO:0010646 regulation of cell communication 40.6667 4 yes
GO:0031323 regulation of cellular metabolic process 40.6667 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 39.3333 4 yes
GO:0051128 regulation of cellular component organization 38.6667 4 yes
GO:0006996 organelle organization 33.3333 4 yes
GO:0051049 regulation of transport 32.6667 4 yes
GO:0051246 regulation of protein metabolic process 32.0000 5 yes
GO:0009893 positive regulation of metabolic process 32.0000 4 yes
GO:0010468 regulation of gene expression 30.6667 5 yes
GO:0022607 cellular component assembly 30.6667 4 yes
GO:0010941 regulation of cell death 30.0000 4 yes
GO:0009966 regulation of signal transduction 29.3333 4 yes
GO:0043067 regulation of programmed cell death 28.0000 5 yes
GO:0008104 protein localization 28.0000 4 yes
GO:0042981 regulation of apoptotic process 26.6667 6 yes
GO:0071310 cellular response to organic substance 26.6667 4 yes
GO:0031325 positive regulation of cellular metabolic process 26.6667 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 26.0000 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 24.6667 5 yes
GO:0009889 regulation of biosynthetic process 24.0000 4 yes
GO:0060548 negative regulation of cell death 23.3333 5 yes
GO:0023056 positive regulation of signaling 23.3333 4 yes
GO:0031326 regulation of cellular biosynthetic process 23.3333 5 yes
GO:0060341 regulation of cellular localization 22.6667 4 yes
GO:0071702 organic substance transport 22.6667 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 22.6667 5 yes
GO:0030030 cell projection organization 22.6667 4 yes
GO:0051240 positive regulation of multicellular organismal process 22.0000 4 yes
GO:0009892 negative regulation of metabolic process 22.0000 4 yes
GO:0071705 nitrogen compound transport 21.3333 4 yes
GO:0010647 positive regulation of cell communication 21.3333 5 yes
GO:0043069 negative regulation of programmed cell death 20.6667 6 yes
GO:0009894 regulation of catabolic process 20.6667 4 yes
GO:0007010 cytoskeleton organization 20.6667 5 no
GO:0032880 regulation of protein localization 20.6667 5 yes
GO:0043412 macromolecule modification 20.0000 4 yes
GO:0051050 positive regulation of transport 20.0000 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 20.0000 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 20.0000 5 yes
GO:0036211 protein modification process 20.0000 4 yes
GO:0043066 negative regulation of apoptotic process 19.3333 7 yes
GO:0051130 positive regulation of cellular component organization 19.3333 5 yes
GO:1902531 regulation of intracellular signal transduction 19.3333 5 yes
GO:0048584 positive regulation of response to stimulus 18.6667 4 yes
GO:0050804 modulation of chemical synaptic transmission 18.6667 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 18.6667 5 yes
GO:0051247 positive regulation of protein metabolic process 18.6667 6 yes
GO:0051252 regulation of RNA metabolic process 18.6667 5 yes
GO:0006355 regulation of DNA-templated transcription 18.6667 6 yes
GO:0099177 regulation of trans-synaptic signaling 18.6667 4 yes
GO:0010243 response to organonitrogen compound 18.6667 4 yes
GO:1903506 regulation of nucleic acid-templated transcription 18.6667 7 yes
GO:2001141 regulation of RNA biosynthetic process 18.6667 6 yes
GO:0045595 regulation of cell differentiation 18.0000 4 yes
GO:0048585 negative regulation of response to stimulus 18.0000 4 yes
GO:0120036 plasma membrane bounded cell projection organization 18.0000 5 yes
GO:2000026 regulation of multicellular organismal development 18.0000 4 yes
GO:0031324 negative regulation of cellular metabolic process 18.0000 5 yes
GO:0034330 cell junction organization 18.0000 4 yes
GO:0051094 positive regulation of developmental process 17.3333 4 yes
GO:0051174 regulation of phosphorus metabolic process 17.3333 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 17.3333 6 yes
GO:0015031 protein transport 17.3333 4 yes
GO:0019220 regulation of phosphate metabolic process 17.3333 6 yes
GO:0022603 regulation of anatomical structure morphogenesis 17.3333 4 yes
GO:0031344 regulation of cell projection organization 17.3333 5 yes
GO:0031399 regulation of protein modification process 17.3333 6 yes
GO:0043085 positive regulation of catalytic activity 16.6667 4 yes
GO:0043269 regulation of ion transport 16.6667 5 yes
GO:0010648 negative regulation of cell communication 16.6667 5 yes
GO:0023057 negative regulation of signaling 16.6667 4 yes
GO:0009968 negative regulation of signal transduction 16.0000 5 yes
GO:1901701 cellular response to oxygen-containing compound 16.0000 4 yes
GO:0042325 regulation of phosphorylation 15.3333 7 yes
GO:0006811 ion transport 15.3333 4 yes
GO:0009967 positive regulation of signal transduction 15.3333 5 yes
GO:0010975 regulation of neuron projection development 15.3333 7 yes
GO:0030162 regulation of proteolysis 15.3333 6 yes
GO:0051248 negative regulation of protein metabolic process 14.6667 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 14.0000 6 yes
GO:0051338 regulation of transferase activity 14.0000 4 yes
GO:0071417 cellular response to organonitrogen compound 14.0000 4 yes
GO:1901699 cellular response to nitrogen compound 14.0000 4 yes
GO:0031329 regulation of cellular catabolic process 14.0000 5 yes
GO:0051129 negative regulation of cellular component organization 13.3333 5 yes
GO:0001932 regulation of protein phosphorylation 13.3333 7 yes
GO:0070201 regulation of establishment of protein localization 12.6667 6 yes
GO:0009891 positive regulation of biosynthetic process 12.6667 5 yes
GO:0010942 positive regulation of cell death 12.6667 5 yes
GO:1903829 positive regulation of protein localization 12.6667 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 12.6667 6 yes
GO:0042176 regulation of protein catabolic process 12.6667 5 yes
GO:0043549 regulation of kinase activity 12.0000 5 yes
GO:0045862 positive regulation of proteolysis 12.0000 7 yes
GO:0051223 regulation of protein transport 12.0000 5 yes
GO:0051241 negative regulation of multicellular organismal process 12.0000 4 yes
GO:0010628 positive regulation of gene expression 12.0000 6 yes
GO:0034762 regulation of transmembrane transport 12.0000 4 yes
GO:0043408 regulation of MAPK cascade 11.3333 6 yes
GO:0045937 positive regulation of phosphate metabolic process 11.3333 7 yes
GO:0050808 synapse organization 11.3333 5 yes
GO:0051093 negative regulation of developmental process 11.3333 4 yes
GO:0051254 positive regulation of RNA metabolic process 11.3333 6 yes
GO:0051960 regulation of nervous system development 11.3333 5 yes
GO:0006508 proteolysis 11.3333 4 yes
GO:0060284 regulation of cell development 11.3333 5 yes
GO:0006915 apoptotic process 11.3333 4 yes
GO:0009890 negative regulation of biosynthetic process 11.3333 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 11.3333 6 yes
GO:0010562 positive regulation of phosphorus metabolic process 11.3333 6 yes
GO:0034765 regulation of ion transmembrane transport 11.3333 5 yes
GO:0045893 positive regulation of DNA-templated transcription 10.6667 7 yes
GO:0048878 chemical homeostasis 10.6667 4 yes
GO:0050890 cognition 10.6667 4 yes
GO:1902533 positive regulation of intracellular signal transduction 10.6667 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 10.6667 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 10.6667 8 yes
GO:0031400 negative regulation of protein modification process 10.6667 7 yes
GO:0042327 positive regulation of phosphorylation 10.0000 8 yes
GO:0043065 positive regulation of apoptotic process 10.0000 7 yes
GO:0043068 positive regulation of programmed cell death 10.0000 6 yes
GO:0043270 positive regulation of ion transport 10.0000 5 yes
GO:0043603 cellular amide metabolic process 10.0000 4 yes
GO:0050767 regulation of neurogenesis 10.0000 6 yes
GO:0006357 regulation of transcription by RNA polymerase II 10.0000 7 yes
GO:0006812 cation transport 10.0000 5 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 10.0000 6 yes
GO:1901214 regulation of neuron death 10.0000 5 yes
GO:0010629 negative regulation of gene expression 10.0000 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 10.0000 6 yes
GO:2001233 regulation of apoptotic signaling pathway 10.0000 5 yes
GO:0032386 regulation of intracellular transport 10.0000 5 yes
GO:0045596 negative regulation of cell differentiation 9.3333 5 yes
GO:0045859 regulation of protein kinase activity 9.3333 6 yes
GO:0031401 positive regulation of protein modification process 9.3333 7 yes
GO:0050770 regulation of axonogenesis 8.6667 5 yes
GO:0050801 ion homeostasis 8.6667 5 yes
GO:0051222 positive regulation of protein transport 8.6667 5 yes
GO:0051347 positive regulation of transferase activity 8.6667 5 yes
GO:0055080 cation homeostasis 8.6667 6 yes
GO:0006518 peptide metabolic process 8.6667 4 yes
GO:0098771 inorganic ion homeostasis 8.6667 6 yes
GO:1901215 negative regulation of neuron death 8.6667 6 yes
GO:0030001 metal ion transport 8.6667 6 yes
GO:1904951 positive regulation of establishment of protein localization 8.6667 6 yes
GO:0032388 positive regulation of intracellular transport 8.6667 5 yes
GO:0033157 regulation of intracellular protein transport 8.6667 6 yes
GO:0043086 negative regulation of catalytic activity 8.0000 4 yes
GO:0043393 regulation of protein binding 8.0000 4 yes
GO:0043523 regulation of neuron apoptotic process 8.0000 6 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 8.0000 6 yes
GO:0045936 negative regulation of phosphate metabolic process 8.0000 7 yes
GO:0001934 positive regulation of protein phosphorylation 8.0000 8 yes
GO:0055065 metal ion homeostasis 8.0000 7 yes
GO:0006820 anion transport 8.0000 5 yes
GO:0006873 cellular ion homeostasis 8.0000 4 yes
GO:0009896 positive regulation of catabolic process 8.0000 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 8.0000 6 yes
GO:0030003 cellular cation homeostasis 8.0000 5 yes
GO:0033674 positive regulation of kinase activity 8.0000 6 yes
GO:0042326 negative regulation of phosphorylation 7.3333 8 yes
GO:0043410 positive regulation of MAPK cascade 7.3333 7 yes
GO:0045892 negative regulation of DNA-templated transcription 7.3333 7 yes
GO:0051253 negative regulation of RNA metabolic process 7.3333 6 yes
GO:0006875 cellular metal ion homeostasis 7.3333 6 yes
GO:0072507 divalent inorganic cation homeostasis 7.3333 7 yes
GO:0090316 positive regulation of intracellular protein transport 7.3333 6 yes
GO:0098656 anion transmembrane transport 7.3333 4 yes
GO:1901652 response to peptide 7.3333 4 yes
GO:1902679 negative regulation of RNA biosynthetic process 7.3333 7 yes
GO:1902903 regulation of supramolecular fiber organization 7.3333 5 yes
GO:1903507 negative regulation of nucleic acid-templated transcription 7.3333 8 yes
GO:0030111 regulation of Wnt signaling pathway 7.3333 5 yes
GO:2001234 negative regulation of apoptotic signaling pathway 7.3333 6 yes
GO:0031345 negative regulation of cell projection organization 7.3333 6 yes
GO:0034764 positive regulation of transmembrane transport 7.3333 5 yes
GO:0034767 positive regulation of ion transmembrane transport 7.3333 6 yes
GO:0001817 regulation of cytokine production 6.6667 4 yes
GO:0001933 negative regulation of protein phosphorylation 6.6667 8 yes
GO:0051348 negative regulation of transferase activity 6.6667 5 yes
GO:0002684 positive regulation of immune system process 6.6667 4 yes
GO:0055074 calcium ion homeostasis 6.6667 8 yes
GO:0060828 regulation of canonical Wnt signaling pathway 6.6667 6 yes
GO:0072503 cellular divalent inorganic cation homeostasis 6.6667 6 yes
GO:0010977 negative regulation of neuron projection development 6.6667 7 yes
GO:0015711 organic anion transport 6.6667 5 yes
GO:0045732 positive regulation of protein catabolic process 6.0000 6 yes
GO:0046822 regulation of nucleocytoplasmic transport 6.0000 6 yes
GO:0050776 regulation of immune response 6.0000 4 yes
GO:0051099 positive regulation of binding 6.0000 4 yes
GO:0001819 positive regulation of cytokine production 6.0000 5 yes
GO:0006874 cellular calcium ion homeostasis 6.0000 7 yes
GO:0061136 regulation of proteasomal protein catabolic process 6.0000 6 yes
GO:0070925 organelle assembly 6.0000 5 yes
GO:0071900 regulation of protein serine/threonine kinase activity 6.0000 7 yes
GO:0007613 memory 6.0000 4 yes
GO:1900180 regulation of protein localization to nucleus 6.0000 6 yes
GO:1901653 cellular response to peptide 6.0000 5 yes
GO:0010721 negative regulation of cell development 6.0000 6 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 6.0000 7 yes
GO:0015849 organic acid transport 6.0000 5 yes
GO:0043405 regulation of MAP kinase activity 5.3333 8 yes
GO:0043524 negative regulation of neuron apoptotic process 5.3333 7 yes
GO:0045860 positive regulation of protein kinase activity 5.3333 7 yes
GO:0046942 carboxylic acid transport 5.3333 6 yes
GO:0050768 negative regulation of neurogenesis 5.3333 6 yes
GO:0002009 morphogenesis of an epithelium 5.3333 4 yes
GO:0051402 neuron apoptotic process 5.3333 4 yes
GO:0051961 negative regulation of nervous system development 5.3333 5 yes
GO:0006816 calcium ion transport 5.3333 7 yes
GO:0009895 negative regulation of catabolic process 5.3333 5 yes
GO:0106027 neuron projection organization 5.3333 6 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 5.3333 7 yes
GO:1904645 response to amyloid-beta 5.3333 5 yes
GO:1904646 cellular response to amyloid-beta 5.3333 6 yes
GO:1905039 carboxylic acid transmembrane transport 5.3333 4 yes
GO:0031331 positive regulation of cellular catabolic process 5.3333 6 yes
GO:0033673 negative regulation of kinase activity 5.3333 6 yes
GO:0046824 positive regulation of nucleocytoplasmic transport 4.6667 6 yes
GO:0048666 neuron development 4.6667 4 yes
GO:0051100 negative regulation of binding 4.6667 4 yes
GO:0051952 regulation of amine transport 4.6667 5 yes
GO:0003333 amino acid transmembrane transport 4.6667 5 yes
GO:0006469 negative regulation of protein kinase activity 4.6667 7 yes
GO:0006835 dicarboxylic acid transport 4.6667 7 yes
GO:0006865 amino acid transport 4.6667 5 yes
GO:0062012 regulation of small molecule metabolic process 4.6667 4 yes
GO:0006974 cellular response to DNA damage stimulus 4.6667 4 yes
GO:0098657 import into cell 4.6667 4 yes
GO:1902905 positive regulation of supramolecular fiber organization 4.6667 6 yes
GO:1903321 negative regulation of protein modification by small protein conjugation or removal 4.6667 8 yes
GO:0030182 neuron differentiation 4.6667 4 yes
GO:0031396 regulation of protein ubiquitination 4.6667 8 yes
GO:0032092 positive regulation of protein binding 4.6667 5 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4.0000 8 yes
GO:0050771 negative regulation of axonogenesis 4.0000 6 yes
GO:0050778 positive regulation of immune response 4.0000 5 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 4.0000 8 yes
GO:0001764 neuron migration 4.0000 4 yes
GO:0001919 regulation of receptor recycling 4.0000 4 yes
GO:0051966 regulation of synaptic transmission, glutamatergic 4.0000 6 yes
GO:0007219 Notch signaling pathway 4.0000 4 yes
GO:1900182 positive regulation of protein localization to nucleus 4.0000 6 yes
GO:1901800 positive regulation of proteasomal protein catabolic process 4.0000 7 yes
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 4.0000 8 yes
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 4.0000 5 yes
GO:0030099 myeloid cell differentiation 4.0000 4 yes
GO:0031397 negative regulation of protein ubiquitination 4.0000 9 yes
GO:0032680 regulation of tumor necrosis factor production 4.0000 6 yes
GO:0042307 positive regulation of protein import into nucleus 3.3333 7 yes
GO:0042982 amyloid precursor protein metabolic process 3.3333 4 yes
GO:0043406 positive regulation of MAP kinase activity 3.3333 8 yes
GO:0043467 regulation of generation of precursor metabolites and energy 3.3333 5 yes
GO:0045861 negative regulation of proteolysis 3.3333 7 yes
GO:0045981 positive regulation of nucleotide metabolic process 3.3333 6 yes
GO:0048732 gland development 3.3333 4 yes
GO:0050818 regulation of coagulation 3.3333 4 yes
GO:0001921 positive regulation of receptor recycling 3.3333 5 yes
GO:0002521 leukocyte differentiation 3.3333 4 yes
GO:0051604 protein maturation 3.3333 4 yes
GO:0051938 L-glutamate import 3.3333 6 yes
GO:0051954 positive regulation of amine transport 3.3333 5 yes
GO:0006109 regulation of carbohydrate metabolic process 3.3333 5 yes
GO:0006140 regulation of nucleotide metabolic process 3.3333 5 yes
GO:0006486 protein glycosylation 3.3333 4 yes
GO:0006509 membrane protein ectodomain proteolysis 3.3333 6 yes
GO:0062013 positive regulation of small molecule metabolic process 3.3333 5 yes
GO:0071902 positive regulation of protein serine/threonine kinase activity 3.3333 8 yes
GO:1900542 regulation of purine nucleotide metabolic process 3.3333 6 yes
GO:1900544 positive regulation of purine nucleotide metabolic process 3.3333 7 yes
GO:1902475 L-alpha-amino acid transmembrane transport 3.3333 6 yes
GO:0015800 acidic amino acid transport 3.3333 6 yes
GO:1903131 mononuclear cell differentiation 3.3333 5 yes
GO:0015807 L-amino acid transport 3.3333 5 yes
GO:0015813 L-glutamate transmembrane transport 3.3333 5 yes
GO:0016485 protein processing 3.3333 5 yes
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 3.3333 6 yes
GO:1903578 regulation of ATP metabolic process 3.3333 7 yes
GO:1903580 positive regulation of ATP metabolic process 3.3333 8 yes
GO:0031330 negative regulation of cellular catabolic process 3.3333 6 yes
GO:0032469 endoplasmic reticulum calcium ion homeostasis 3.3333 8 yes
GO:0032760 positive regulation of tumor necrosis factor production 3.3333 7 yes
GO:0033619 membrane protein proteolysis 3.3333 5 yes
GO:0042110 T cell activation 3.3333 4 yes
GO:0042306 regulation of protein import into nucleus 3.3333 7 yes
GO:0042987 amyloid precursor protein catabolic process 2.6667 5 yes
GO:0043470 regulation of carbohydrate catabolic process 2.6667 5 yes
GO:0044070 regulation of anion transport 2.6667 6 yes
GO:0045913 positive regulation of carbohydrate metabolic process 2.6667 5 yes
GO:0048143 astrocyte activation 2.6667 4 yes
GO:0048534 hematopoietic or lymphoid organ development 2.6667 4 yes
GO:0048538 thymus development 2.6667 5 yes
GO:0048854 brain morphogenesis 2.6667 4 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 2.6667 4 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 2.6667 4 yes
GO:0051955 regulation of amino acid transport 2.6667 6 yes
GO:0051957 positive regulation of amino acid transport 2.6667 6 yes
GO:0060562 epithelial tube morphogenesis 2.6667 4 yes
GO:0060998 regulation of dendritic spine development 2.6667 4 yes
GO:0060999 positive regulation of dendritic spine development 2.6667 5 yes
GO:0007033 vacuole organization 2.6667 5 yes
GO:0089718 amino acid import across plasma membrane 2.6667 4 yes
GO:1903793 positive regulation of anion transport 2.6667 6 yes
GO:1905906 regulation of amyloid fibril formation 2.6667 6 yes
GO:1905908 positive regulation of amyloid fibril formation 2.6667 7 yes
GO:1990535 neuron projection maintenance 2.6667 7 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 2.6667 6 yes
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 2.6667 7 yes
GO:0032890 regulation of organic acid transport 2.6667 5 yes
GO:0032892 positive regulation of organic acid transport 2.6667 5 yes
GO:0045821 positive regulation of glycolytic process 2.0000 6 yes
GO:0048705 skeletal system morphogenesis 2.0000 4 yes
GO:0050435 amyloid-beta metabolic process 2.0000 5 yes
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 2.0000 9 yes
GO:0050820 positive regulation of coagulation 2.0000 5 yes
GO:0050851 antigen receptor-mediated signaling pathway 2.0000 5 yes
GO:0050852 T cell receptor signaling pathway 2.0000 6 yes
GO:0051101 regulation of DNA binding 2.0000 4 yes
GO:0000045 autophagosome assembly 2.0000 6 yes
GO:0002036 regulation of L-glutamate import across plasma membrane 2.0000 7 yes
GO:0002038 positive regulation of L-glutamate import across plasma membrane 2.0000 7 yes
GO:0002244 hematopoietic progenitor cell differentiation 2.0000 4 yes
GO:0002265 astrocyte activation involved in immune response 2.0000 4 yes
GO:0051438 regulation of ubiquitin-protein transferase activity 2.0000 5 yes
GO:0051444 negative regulation of ubiquitin-protein transferase activity 2.0000 6 yes
GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis 2.0000 9 yes
GO:0002573 myeloid leukocyte differentiation 2.0000 5 yes
GO:0003143 embryonic heart tube morphogenesis 2.0000 4 yes
GO:0006110 regulation of glycolytic process 2.0000 6 yes
GO:0060075 regulation of resting membrane potential 2.0000 4 yes
GO:0061097 regulation of protein tyrosine kinase activity 2.0000 7 yes
GO:0007176 regulation of epidermal growth factor-activated receptor activity 2.0000 4 yes
GO:0007220 Notch receptor processing 2.0000 4 yes
GO:0098712 L-glutamate import across plasma membrane 2.0000 5 yes
GO:0009952 anterior/posterior pattern specification 2.0000 4 yes
GO:0009953 dorsal/ventral pattern formation 2.0000 4 yes
GO:0010958 regulation of amino acid import across plasma membrane 2.0000 6 yes
GO:1903051 negative regulation of proteolysis involved in protein catabolic process 2.0000 8 yes
GO:1903789 regulation of amino acid transmembrane transport 2.0000 5 yes
GO:0021904 dorsal/ventral neural tube patterning 2.0000 5 yes
GO:1903959 regulation of anion transmembrane transport 2.0000 6 yes
GO:1903961 positive regulation of anion transmembrane transport 2.0000 7 yes
GO:1904796 regulation of core promoter binding 2.0000 6 yes
GO:1905037 autophagosome organization 2.0000 6 yes
GO:0030326 embryonic limb morphogenesis 2.0000 5 yes
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 2.0000 7 yes
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 2.0000 7 yes
GO:2000272 negative regulation of signaling receptor activity 2.0000 4 yes
GO:2000677 regulation of transcription regulatory region DNA binding 2.0000 5 yes
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 2.0000 8 yes
GO:0034205 amyloid-beta formation 2.0000 6 yes
GO:0035108 limb morphogenesis 2.0000 4 yes
GO:0035113 embryonic appendage morphogenesis 2.0000 4 yes
GO:0043011 myeloid dendritic cell differentiation 1.3333 5 yes
GO:0043392 negative regulation of DNA binding 1.3333 5 yes
GO:0043589 skin morphogenesis 1.3333 4 yes
GO:0001773 myeloid dendritic cell activation 1.3333 4 yes
GO:0001947 heart looping 1.3333 5 yes
GO:0002285 lymphocyte activation involved in immune response 1.3333 4 yes
GO:0002286 T cell activation involved in immune response 1.3333 5 yes
GO:0006839 mitochondrial transport 1.3333 4 yes
GO:0061099 negative regulation of protein tyrosine kinase activity 1.3333 8 yes
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1.3333 5 yes
GO:0097028 dendritic cell differentiation 1.3333 6 yes
GO:1901184 regulation of ERBB signaling pathway 1.3333 5 yes
GO:1901185 negative regulation of ERBB signaling pathway 1.3333 6 yes
GO:0015695 organic cation transport 1.3333 5 yes
GO:0015871 choline transport 1.3333 5 yes
GO:0021795 cerebral cortex cell migration 1.3333 6 yes
GO:0021870 Cajal-Retzius cell differentiation 1.3333 7 yes
GO:0021885 forebrain cell migration 1.3333 4 yes
GO:0021895 cerebral cortex neuron differentiation 1.3333 6 yes
GO:0021953 central nervous system neuron differentiation 1.3333 5 yes
GO:0022029 telencephalon cell migration 1.3333 5 yes
GO:1904797 negative regulation of core promoter binding 1.3333 7 yes
GO:0031293 membrane protein intracellular domain proteolysis 1.3333 6 yes
GO:2000678 negative regulation of transcription regulatory region DNA binding 1.3333 6 yes
GO:0035282 segmentation 1.3333 4 yes
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1.3333 6 yes
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1.3333 7 yes

Disease

Term Name % Distance from top the of the tree Annotated in PSN1_HUMAN
DOID:331 central nervous system disease 3.3333 3 no
DOID:1289 neurodegenerative disease 2.0000 4 no
DOID:114 heart disease 2.0000 3 no
DOID:936 brain disease 1.3333 4 no
DOID:231 motor neuron disease 1.3333 5 no
DOID:0050700 cardiomyopathy 1.3333 4 no
DOID:0060036 intrinsic cardiomyopathy 1.3333 5 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
APBA3_HUMAN [view interactions] Low throughput no yes
EFNB1_HUMAN [view interactions] Low throughput no yes
VPP1_HUMAN [view entry] [view interactions] Low throughput yes yes
STT3B_HUMAN [view interactions] Low throughput no yes
CALR_HUMAN [view interactions] Low throughput no yes
TNR16_HUMAN [view entry] [view interactions] Low throughput yes no
GSAP_HUMAN [view interactions] Low throughput no no
FLOT2_HUMAN [view entry] [view interactions] Low throughput yes yes
STXB1_HUMAN [view entry] [view interactions] Low throughput yes yes
NEUM_HUMAN [view entry] [view interactions] Low throughput yes yes
GTR3_HUMAN [view interactions] Low throughput no yes
NMDZ1_HUMAN [view entry] [view interactions] Low throughput yes yes
ARC_HUMAN [view entry] [view interactions] Low throughput yes no
PSN2_HUMAN [view entry] [view interactions] Low throughput yes no
CSEN_HUMAN [view interactions] Low throughput no no
NOTC1_HUMAN [view interactions] Low throughput no yes
PEMT_HUMAN [view interactions] Low throughput no yes
GFAP_HUMAN [view entry] [view interactions] Low throughput yes no
ICAM5_HUMAN [view entry] [view interactions] Low throughput yes yes
BCL2_HUMAN [view interactions] Low throughput no no
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
KCIP4_HUMAN [view interactions] Low throughput no no
CIB1_HUMAN [view interactions] Low throughput no no
YMEL1_HUMAN [view interactions] Low throughput no yes
ETFA_HUMAN [view interactions] Low throughput no yes
FKBP8_HUMAN [view entry] [view interactions] Low throughput yes yes
CSTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
FBXW7_HUMAN [view interactions] Low throughput no yes
CTNA1_HUMAN [view entry] [view interactions] Low throughput yes yes
TF7L2_HUMAN [view interactions] Low throughput no yes
HERP1_HUMAN [view interactions] Low throughput no yes
ERN1_HUMAN [view interactions] Low throughput no yes
TRAF6_HUMAN [view interactions] Low throughput no yes
IRAK2_HUMAN [view interactions] Low throughput no yes
FLNB_HUMAN [view interactions] Low throughput no no
DLL1_HUMAN [view interactions] Low throughput no no
FLNA_HUMAN [view entry] [view interactions] Low throughput yes no
P85A_HUMAN [view interactions] Low throughput no yes
B2CL1_HUMAN [view interactions] Low throughput no yes
NMDE1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBQL1_HUMAN [view interactions] Low throughput no yes
TGFR1_HUMAN [view interactions] Low throughput no no
PKP4_HUMAN [view entry] [view interactions] Low throughput yes yes
S61A1_HUMAN [view interactions] Low throughput no no
PE2R4_HUMAN [view interactions] Low throughput no yes
CADH2_HUMAN [view entry] [view interactions] Low throughput yes no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
HTRA2_HUMAN [view interactions] Low throughput no yes
BACE1_HUMAN [view interactions] Low throughput no yes
APH1A_HUMAN [view interactions] Low throughput no yes
APBA1_HUMAN [view interactions] Low throughput no no
APBA2_HUMAN [view interactions] Low throughput no yes
PLD1_HUMAN [view interactions] Low throughput no no
TREM2_HUMAN [view interactions] Low throughput no yes
RYR2_HUMAN [view entry] [view interactions] Low throughput yes yes
PLAK_HUMAN [view entry] [view interactions] Low throughput yes yes
MK09_HUMAN [view interactions] Low throughput no yes
PSB1_HUMAN [view interactions] Low throughput no yes
PSA5_HUMAN [view interactions] Low throughput no yes
ERLN2_HUMAN [view entry] [view interactions] Low throughput yes yes
PSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
BI1_HUMAN [view interactions] Low throughput no yes
PEN2_HUMAN [view interactions] Low throughput no yes
NICA_HUMAN [view interactions] Low throughput no yes
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
SYT1_HUMAN [view entry] [view interactions] Low throughput yes no
MTCH1_HUMAN [view entry] [view interactions] Low throughput yes yes
ECSIT_HUMAN [view interactions] Low throughput no yes
SYN1_HUMAN [view entry] [view interactions] Low throughput yes no
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
CTND2_HUMAN [view entry] [view interactions] High throughput yes no
DC121_HUMAN [view interactions] High throughput no yes
DC122_HUMAN [view interactions] High throughput no yes
NFL_HUMAN [view entry] [view interactions] High throughput yes yes
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
IDH3B_HUMAN [view entry] [view interactions] High throughput yes yes
MTAP2_HUMAN [view entry] [view interactions] High throughput yes yes
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
HS12A_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
ATPO_HUMAN [view interactions] High throughput no yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
RS16_HUMAN [view entry] [view interactions] High throughput yes yes
BRSK1_HUMAN [view entry] [view interactions] High throughput yes no
CTNA2_HUMAN [view entry] [view interactions] High throughput yes yes
GSTM2_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
ATPG_HUMAN [view interactions] High throughput no yes
SYFA_HUMAN [view entry] [view interactions] High throughput yes yes
NSF_HUMAN [view entry] [view interactions] High throughput yes yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
TBA1B_HUMAN [view entry] [view interactions] High throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A3_HUMAN [view entry] [view interactions] High throughput yes no
DCE1_HUMAN [view entry] [view interactions] High throughput yes yes
CAMKV_HUMAN [view entry] [view interactions] High throughput yes yes
KPYM_HUMAN [view interactions] High throughput no yes
KCC2D_HUMAN [view entry] [view interactions] High throughput yes yes
CPNE6_HUMAN [view entry] [view interactions] High throughput yes yes
MAP6_HUMAN [view entry] [view interactions] High throughput yes yes
MPCP_HUMAN [view entry] [view interactions] High throughput yes no
SYT5_HUMAN [view entry] [view interactions] High throughput yes no
SMAP1_HUMAN [view interactions] High throughput no yes
CPNE4_HUMAN [view interactions] High throughput no no
DPYL3_HUMAN [view entry] [view interactions] High throughput yes yes
TMED2_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
GCDH_HUMAN [view interactions] High throughput no yes
CDK5_HUMAN [view entry] [view interactions] High throughput yes yes
KANK2_HUMAN [view entry] [view interactions] High throughput yes yes
PRAM_HUMAN [view interactions] High throughput no no
RAB3A_HUMAN [view entry] [view interactions] High throughput yes yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
TYDP2_HUMAN [view interactions] High throughput no no
MYCT_HUMAN [view interactions] High throughput no yes
ATP9A_HUMAN [view interactions] High throughput no yes
HCN2_HUMAN [view entry] [view interactions] High throughput yes no
NDUS7_HUMAN [view entry] [view interactions] High throughput yes no
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
CNTP1_HUMAN [view entry] [view interactions] High throughput yes yes
GTR14_HUMAN [view interactions] High throughput no no
AOFB_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
AP1M2_HUMAN [view interactions] High throughput no no
CP2CI_HUMAN [view interactions] High throughput no no
CP2C8_HUMAN [view interactions] High throughput no no
FXL12_HUMAN [view interactions] High throughput no yes
NOS3_HUMAN [view interactions] High throughput no no
PDCD4_HUMAN [view interactions] High throughput no yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
RD23A_HUMAN [view interactions] High throughput no yes
RHEB_HUMAN [view entry] [view interactions] High throughput yes yes
STALP_HUMAN [view interactions] High throughput no yes
RNF32_HUMAN [view interactions] High throughput no no
FGF13_HUMAN [view interactions] High throughput no no
HMGB1_HUMAN [view interactions] High throughput no yes
ITSN2_HUMAN [view entry] [view interactions] High throughput yes yes
SCN1A_HUMAN [view interactions] High throughput no no
SOAT_HUMAN [view interactions] High throughput no no
APH1B_HUMAN [view interactions] High throughput no no
NOTC2_HUMAN [view interactions] High throughput no yes
NOTC3_HUMAN [view interactions] High throughput no yes
NOTC4_HUMAN [view interactions] High throughput no no
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
UNK_HUMAN [view interactions] High throughput no yes
ACTN1_HUMAN [view entry] [view interactions] High throughput yes yes
EFHD1_HUMAN [view interactions] High throughput no no
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
SPP2B_HUMAN [view interactions] High throughput no yes
RMD3_HUMAN [view interactions] High throughput no yes
CADH8_HUMAN [view interactions] High throughput no no
ENSA_HUMAN [view interactions] High throughput no yes
BGAL_HUMAN [view interactions] High throughput no yes
COF1_HUMAN [view entry] [view interactions] High throughput yes no
UMPS_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
SCOT1_HUMAN [view entry] [view interactions] High throughput yes yes
TSN5_HUMAN [view interactions] High throughput no no
F10A1_HUMAN [view interactions] High throughput no yes
NAAA_HUMAN [view interactions] High throughput no yes
TM11B_HUMAN [view interactions] High throughput no no
SIA4A_HUMAN [view interactions] High throughput no yes
CAD12_HUMAN [view interactions] High throughput no no
VIPR1_HUMAN [view interactions] High throughput no yes
HUMMR_HUMAN [view interactions] High throughput no yes
SERP2_HUMAN [view interactions] High throughput no no
VASN_HUMAN [view interactions] High throughput no yes
SNG1_HUMAN [view entry] [view interactions] High throughput yes yes
DNER_HUMAN [view interactions] High throughput no yes
SG196_HUMAN [view interactions] High throughput no yes
ANPRA_HUMAN [view interactions] High throughput no no
GPR45_HUMAN [view interactions] High throughput no no
PXDC2_HUMAN [view interactions] High throughput no yes
DOXA2_HUMAN [view interactions] High throughput no no
DSG2_HUMAN [view interactions] High throughput no no
RAMP3_HUMAN [view interactions] High throughput no no
DAG1_HUMAN [view entry] [view interactions] High throughput yes no
MFD4A_HUMAN [view interactions] High throughput no yes
ITB1_HUMAN [view entry] [view interactions] High throughput yes no
P2RY8_HUMAN [view interactions] High throughput no no
ANPRC_HUMAN [view interactions] High throughput no no
KLRB1_HUMAN [view interactions] High throughput no yes
S1PR4_HUMAN [view interactions] High throughput no no
ZW10_HUMAN [view interactions] High throughput no yes
TX1B3_HUMAN [view interactions] High throughput no no
CNOT7_HUMAN [view interactions] High throughput no no
AGRE5_HUMAN [view interactions] High throughput no no
RHBD2_HUMAN [view interactions] High throughput no yes
PTPR2_HUMAN [view interactions] High throughput no yes
PCBP2_HUMAN [view entry] [view interactions] High throughput yes yes
EAA3_HUMAN [view entry] [view interactions] High throughput yes yes
DJB12_HUMAN [view interactions] High throughput no yes
DNJC2_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
VAMP3_HUMAN [view entry] [view interactions] High throughput yes no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
EMC2_HUMAN [view interactions] High throughput no yes
TMM43_HUMAN [view interactions] High throughput no no
TMM33_HUMAN [view entry] [view interactions] High throughput yes yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
TMEDA_HUMAN [view interactions] High throughput no yes
DHX9_HUMAN [view interactions] High throughput no yes
TMCO1_HUMAN [view interactions] High throughput no yes
DTNA_HUMAN [view entry] [view interactions] High throughput yes yes
TBL3_HUMAN [view interactions] High throughput no yes
NDUS8_HUMAN [view interactions] High throughput no yes
STT3A_HUMAN [view interactions] High throughput no yes
IVD_HUMAN [view interactions] High throughput no yes
SSRD_HUMAN [view interactions] High throughput no yes
TRXR2_HUMAN [view interactions] High throughput no yes
SSRG_HUMAN [view interactions] High throughput no yes
MIA40_HUMAN [view interactions] High throughput no yes
SSRA_HUMAN [view entry] [view interactions] High throughput yes yes
MCFD2_HUMAN [view interactions] High throughput no yes
SRPRB_HUMAN [view entry] [view interactions] High throughput yes no
AL9A1_HUMAN [view interactions] High throughput no yes
SOAT1_HUMAN [view interactions] High throughput no no
6PGD_HUMAN [view entry] [view interactions] High throughput yes no
AAAT_HUMAN [view interactions] High throughput no no
CC50A_HUMAN [view interactions] High throughput no yes
SKP1_HUMAN [view interactions] High throughput no yes
TOM22_HUMAN [view interactions] High throughput no yes
SCD_HUMAN [view entry] [view interactions] High throughput yes yes
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
SAR1A_HUMAN [view entry] [view interactions] High throughput yes yes
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
RL38_HUMAN [view entry] [view interactions] High throughput yes yes
RDH11_HUMAN [view interactions] High throughput no no
RAGP1_HUMAN [view entry] [view interactions] High throughput yes yes
HACD3_HUMAN [view interactions] High throughput no yes
PSMD2_HUMAN [view entry] [view interactions] High throughput yes yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
PRS6A_HUMAN [view entry] [view interactions] High throughput yes yes
PRS7_HUMAN [view interactions] High throughput no yes
PSB5_HUMAN [view interactions] High throughput no yes
PSB2_HUMAN [view interactions] High throughput no yes
PSA7_HUMAN [view interactions] High throughput no yes
PSA6_HUMAN [view interactions] High throughput no yes
PSA4_HUMAN [view entry] [view interactions] High throughput yes yes
PSA2_HUMAN [view interactions] High throughput no yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
MLF1_HUMAN [view entry] [view interactions] High throughput yes yes
MLEC_HUMAN [view interactions] High throughput no no
MAGB2_HUMAN [view interactions] High throughput no no
EMC1_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
DHB12_HUMAN [view entry] [view interactions] High throughput yes yes
ESYT1_HUMAN [view entry] [view interactions] High throughput yes yes
FAF2_HUMAN [view interactions] High throughput no yes
FADS2_HUMAN [view interactions] High throughput no yes
FADS1_HUMAN [view interactions] High throughput no yes
IF4G1_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC7_HUMAN [view interactions] High throughput no yes
DJB11_HUMAN [view interactions] High throughput no yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
DHC24_HUMAN [view interactions] High throughput no yes
DEGS1_HUMAN [view interactions] High throughput no no
DDX20_HUMAN [view interactions] High throughput no no
OST48_HUMAN [view entry] [view interactions] High throughput yes yes
CP51A_HUMAN [view interactions] High throughput no no
EMC8_HUMAN [view interactions] High throughput no no
CHM1A_HUMAN [view entry] [view interactions] High throughput yes no
CDN2A_HUMAN [view interactions] High throughput no yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
ARL1_HUMAN [view interactions] High throughput no yes
ARF4_HUMAN [view entry] [view interactions] High throughput yes no
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
GSTP1_HUMAN [view entry] [view interactions] High throughput yes no
GRPE1_HUMAN [view interactions] High throughput no yes
G3PT_HUMAN [view interactions] High throughput no no
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
GSTM5_HUMAN [view interactions] High throughput no yes
GSTM1_HUMAN [view interactions] High throughput no yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
TBB5_HUMAN [view interactions] High throughput no yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
AINX_HUMAN [view entry] [view interactions] High throughput yes yes
SFXN3_HUMAN [view entry] [view interactions] High throughput yes yes
CMC1_HUMAN [view entry] [view interactions] High throughput yes yes
LANC1_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
TBB4A_HUMAN [view interactions] High throughput no yes
EF1A2_HUMAN [view entry] [view interactions] High throughput yes yes
MBP_HUMAN [view entry] [view interactions] High throughput yes no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
GHC1_HUMAN [view entry] [view interactions] High throughput yes yes
RP3A_HUMAN [view entry] [view interactions] High throughput yes yes
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
TBB2B_HUMAN [view entry] [view interactions] High throughput yes yes
ACTS_HUMAN [view interactions] High throughput no no
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
ADT2_HUMAN [view entry] [view interactions] High throughput yes yes
EPHB1_HUMAN [view interactions] Computational no no
EPHB3_HUMAN [view interactions] Computational no yes
FBW1B_HUMAN [view interactions] Computational no yes
E2AK3_HUMAN [view interactions] Computational no yes
DTX2_HUMAN [view interactions] Computational no yes
EPHB2_HUMAN [view entry] [view interactions] Computational yes yes
NFX1_HUMAN [view interactions] Computational no yes
ZN274_HUMAN [view interactions] Computational no yes
KAPCG_HUMAN [view interactions] Computational no no
SORT_HUMAN [view interactions] Computational no yes
ITPR2_HUMAN [view interactions] Computational no yes
KAPCA_HUMAN [view entry] [view interactions] Computational yes yes
DTX4_HUMAN [view interactions] Computational no yes
ITPR3_HUMAN [view interactions] Computational no yes
DTX1_HUMAN [view interactions] Computational no yes
CENPR_HUMAN [view interactions] Computational no yes
NFIC_HUMAN [view interactions] Computational no yes
GNPTA_HUMAN [view interactions] Computational no yes
EPHB4_HUMAN [view interactions] Computational no yes
YBOX1_HUMAN [view interactions] Computational no yes
IDE_HUMAN [view interactions] Computational no yes
ANXA2_HUMAN [view entry] [view interactions] Computational yes no
RB11A_HUMAN [view entry] [view interactions] Computational yes yes
NGF_HUMAN [view interactions] Computational no no
SDC3_HUMAN [view interactions] Computational no yes
FGFR3_HUMAN [view interactions] Computational no yes
CNTN1_HUMAN [view entry] [view interactions] Computational yes yes
NRG2_HUMAN [view interactions] Computational no yes
KAPCB_HUMAN [view entry] [view interactions] Computational yes yes
GRB2_HUMAN [view entry] [view interactions] Computational yes yes
NRG3_HUMAN [view interactions] Computational no no
CAD17_HUMAN [view interactions] Computational no no
ERBB4_HUMAN [view entry] [view interactions] Computational yes yes
NRG4_HUMAN [view interactions] Computational no no
ACES_HUMAN [view interactions] Computational no no