CTND1_HUMAN
Evidence for PS localization
Functions
Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed, PubMed). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed, PubMed). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000915 | TRG_NES_CRM1_1 | TRG | 942 | 956 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CTND1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 44.8819 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 44.8819 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 44.8819 | 4 | no |
| GO:0019900 | kinase binding | 29.1339 | 4 | yes |
| GO:0019901 | protein kinase binding | 29.1339 | 5 | yes |
| GO:0005524 | ATP binding | 25.9843 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 25.9843 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 25.9843 | 5 | no |
| GO:0045296 | cadherin binding | 22.0472 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 22.0472 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 22.0472 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 22.0472 | 6 | no |
| GO:0016301 | kinase activity | 20.4724 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CTND1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 74.8031 | 4 | no |
| GO:0010646 | regulation of cell communication | 62.9921 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 62.2047 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 60.6299 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 59.8425 | 4 | no |
| GO:0009966 | regulation of signal transduction | 57.4803 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 55.9055 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 55.9055 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 55.1181 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 53.5433 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.5433 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 50.3937 | 5 | no |
| GO:0051049 | regulation of transport | 46.4567 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 46.4567 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 44.8819 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 44.0945 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 44.0945 | 5 | no |
| GO:0022607 | cellular component assembly | 44.0945 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 41.7323 | 6 | no |
| GO:0008104 | protein localization | 41.7323 | 4 | no |
| GO:0010468 | regulation of gene expression | 41.7323 | 5 | no |
| GO:0006996 | organelle organization | 40.9449 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 40.1575 | 5 | no |
| GO:0023056 | positive regulation of signaling | 39.3701 | 4 | no |
| GO:0071310 | cellular response to organic substance | 37.0079 | 4 | no |
| GO:0030030 | cell projection organization | 35.4331 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 34.6457 | 5 | no |
| GO:0033043 | regulation of organelle organization | 33.8583 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 33.0709 | 6 | no |
| GO:0031399 | regulation of protein modification process | 33.0709 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 33.0709 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 32.2835 | 5 | no |
| GO:0060341 | regulation of cellular localization | 32.2835 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.4961 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 31.4961 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 31.4961 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 31.4961 | 4 | no |
| GO:0010941 | regulation of cell death | 30.7087 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 30.7087 | 7 | no |
| GO:0045595 | regulation of cell differentiation | 30.7087 | 4 | no |
| GO:0051050 | positive regulation of transport | 30.7087 | 4 | no |
| GO:0071702 | organic substance transport | 30.7087 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 30.7087 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 30.7087 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 29.9213 | 7 | no |
| GO:0032880 | regulation of protein localization | 29.9213 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 29.9213 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 29.9213 | 4 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 29.1339 | 7 | no |
| GO:0031344 | regulation of cell projection organization | 29.1339 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.1339 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 29.1339 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 29.1339 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 29.1339 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 29.1339 | 5 | no |
| GO:0042327 | positive regulation of phosphorylation | 28.3465 | 8 | no |
| GO:0043067 | regulation of programmed cell death | 28.3465 | 5 | no |
| GO:0071705 | nitrogen compound transport | 28.3465 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 28.3465 | 5 | no |
| GO:0007010 | cytoskeleton organization | 28.3465 | 5 | no |
| GO:0036211 | protein modification process | 28.3465 | 4 | no |
| GO:0043412 | macromolecule modification | 28.3465 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 28.3465 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 28.3465 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 27.5591 | 6 | no |
| GO:2000145 | regulation of cell motility | 27.5591 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 27.5591 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 27.5591 | 7 | no |
| GO:0030334 | regulation of cell migration | 26.7717 | 5 | no |
| GO:0043408 | regulation of MAPK cascade | 26.7717 | 6 | no |
| GO:0051094 | positive regulation of developmental process | 26.7717 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 25.9843 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.9843 | 5 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 25.9843 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.9843 | 6 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 25.9843 | 8 | no |
| GO:0010243 | response to organonitrogen compound | 25.9843 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.1969 | 4 | no |
| GO:0034330 | cell junction organization | 25.1969 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 24.4094 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.4094 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.4094 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 24.4094 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 24.4094 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 23.6220 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.6220 | 5 | no |
| GO:0080134 | regulation of response to stress | 23.6220 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 23.6220 | 6 | no |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 23.6220 | 4 | no |
| GO:0008284 | positive regulation of cell population proliferation | 23.6220 | 5 | no |
| GO:0010628 | positive regulation of gene expression | 22.8346 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.8346 | 6 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 22.8346 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.8346 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 22.8346 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 22.8346 | 4 | no |
| GO:0015031 | protein transport | 22.8346 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.8346 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.8346 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 22.8346 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 22.8346 | 5 | no |
| GO:0060627 | regulation of vesicle-mediated transport | 22.0472 | 4 | no |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 22.0472 | 5 | no |
| GO:0043549 | regulation of kinase activity | 21.2598 | 5 | no |
| GO:0051347 | positive regulation of transferase activity | 21.2598 | 5 | no |
| GO:0060548 | negative regulation of cell death | 21.2598 | 5 | no |
| GO:1901699 | cellular response to nitrogen compound | 21.2598 | 4 | no |
| GO:0009894 | regulation of catabolic process | 21.2598 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.2598 | 6 | no |
| GO:0045597 | positive regulation of cell differentiation | 20.4724 | 5 | no |
| GO:0071417 | cellular response to organonitrogen compound | 20.4724 | 4 | no |
| GO:0014070 | response to organic cyclic compound | 20.4724 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 20.4724 | 4 | no |
| GO:0016310 | phosphorylation | 20.4724 | 5 | no |
| GO:0002684 | positive regulation of immune system process | 20.4724 | 4 | no |
| GO:0034329 | cell junction assembly | 18.1102 | 5 | yes |
| GO:0045216 | cell-cell junction organization | 17.3228 | 5 | yes |
| GO:0007043 | cell-cell junction assembly | 12.5984 | 6 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 11.0236 | 5 | yes |
| GO:0016055 | Wnt signaling pathway | 9.4488 | 5 | yes |
| GO:0060828 | regulation of canonical Wnt signaling pathway | 9.4488 | 6 | yes |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 9.4488 | 4 | yes |
| GO:0007420 | brain development | 5.5118 | 4 | yes |
| GO:0030178 | negative regulation of Wnt signaling pathway | 5.5118 | 6 | yes |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 5.5118 | 7 | yes |
| GO:0050821 | protein stabilization | 3.9370 | 4 | yes |
| GO:0044331 | cell-cell adhesion mediated by cadherin | 1.5748 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in CTND1_HUMAN |
|---|---|---|---|---|
| DOID:0060038 | specific developmental disorder | 1.5748 | 3 | no |
| DOID:1059 | intellectual disability | 1.5748 | 4 | no |
| DOID:0111962 | combined immunodeficiency | 1.5748 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.5748 | 3 | no |
| DOID:0050686 | organ system cancer | 1.5748 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KAISO_HUMAN | [view interactions] | Low throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | Low throughput | no | yes |
| FRMD5_HUMAN | [view interactions] | Low throughput | no | no |
| PLPP3_HUMAN | [view interactions] | Low throughput | no | no |
| SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CADH2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTPRJ_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN11_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| RET_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH5_HUMAN | [view interactions] | Low throughput | no | yes |
| NANO1_HUMAN | [view interactions] | Low throughput | no | yes |
| AGO2_HUMAN | [view interactions] | Low throughput | no | yes |
| PABP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COHA1_HUMAN | [view interactions] | Low throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CADH3_HUMAN | [view interactions] | Low throughput | no | no |
| MUC1_HUMAN | [view interactions] | Low throughput | no | no |
| PTN6_HUMAN | [view interactions] | Low throughput | no | no |
| PTPRM_HUMAN | [view interactions] | Low throughput | no | yes |
| GSK3A_HUMAN | [view interactions] | Low throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KC1E_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RGRF1_HUMAN | [view interactions] | Low throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
| LG3BP_HUMAN | [view interactions] | Low throughput | no | no |
| VAV2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOH_HUMAN | [view interactions] | Low throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | Low throughput | no | yes |
| MK03_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAD11_HUMAN | [view interactions] | Low throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDR48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| RIPK3_HUMAN | [view interactions] | High throughput | no | no |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHG7_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| TBX5_HUMAN | [view interactions] | High throughput | no | no |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| DACT3_HUMAN | [view interactions] | High throughput | no | yes |
| DACT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DACT2_HUMAN | [view interactions] | High throughput | no | yes |
| MCM7_HUMAN | [view interactions] | High throughput | no | no |
| HSC20_HUMAN | [view interactions] | High throughput | no | yes |
| TNR6A_HUMAN | [view interactions] | High throughput | no | yes |
| TRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| IRS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXB1_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMM17_HUMAN | [view interactions] | High throughput | no | yes |
| TM216_HUMAN | [view interactions] | High throughput | no | no |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTDSL_HUMAN | [view interactions] | High throughput | no | no |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCTD6_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3B_HUMAN | [view interactions] | High throughput | no | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHIP1_HUMAN | [view interactions] | High throughput | no | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATP4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| PP4R1_HUMAN | [view interactions] | High throughput | no | yes |
| ELF5_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR7_HUMAN | [view interactions] | High throughput | no | no |
| CADH8_HUMAN | [view interactions] | High throughput | no | no |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TGFB1_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| R144A_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| NACAM_HUMAN | [view interactions] | High throughput | no | no |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| BLK_HUMAN | [view interactions] | High throughput | no | no |
| CO1A1_HUMAN | [view interactions] | High throughput | no | yes |
| PIP_HUMAN | [view interactions] | High throughput | no | no |
| TX1B3_HUMAN | [view interactions] | High throughput | no | no |
| SESQ1_HUMAN | [view interactions] | High throughput | no | no |
| KLH22_HUMAN | [view interactions] | High throughput | no | no |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RND1_HUMAN | [view interactions] | High throughput | no | no |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARVC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWC2_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXD3_HUMAN | [view interactions] | High throughput | no | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PANX1_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX6_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| VP33B_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SLIT1_HUMAN | [view interactions] | Computational | no | no |
| PAK2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PAK3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| DYN2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GLIS2_HUMAN | [view interactions] | Computational | no | no |
| PI51C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAD26_HUMAN | [view interactions] | Computational | no | yes |
| PAK1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VASP_HUMAN | [view interactions] | Computational | no | yes |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAP1A_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GRIA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| EPHA2_HUMAN | [view interactions] | Computational | no | no |
| AJUBA_HUMAN | [view interactions] | Computational | no | yes |
| MET_HUMAN | [view interactions] | Computational | no | yes |
| RHG35_HUMAN | [view interactions] | Computational | no | yes |
| DSG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ZO1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| EXOC4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FMN1_HUMAN | [view interactions] | Computational | no | no |
| SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AXIN1_HUMAN | [view interactions] | Computational | no | yes |
| EFNA1_HUMAN | [view interactions] | Computational | no | no |
| KIF23_HUMAN | [view interactions] | Computational | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| IGF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KIFC3_HUMAN | [view interactions] | Computational | no | no |
| MGAT3_HUMAN | [view interactions] | Computational | no | yes |
| MMP7_HUMAN | [view interactions] | Computational | no | no |
| VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MEP1B_HUMAN | [view interactions] | Computational | no | no |
| CADH4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| GNA12_HUMAN | [view interactions] | Computational | no | no |
| ROBO1_HUMAN | [view interactions] | Computational | no | yes |
| FER_HUMAN | [view interactions] | Computational | no | yes |
| CAD17_HUMAN | [view interactions] | Computational | no | no |
| ZO3_HUMAN | [view interactions] | Computational | no | yes |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| EGF_HUMAN | [view interactions] | Computational | no | no |
| RAC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ZYX_HUMAN | [view interactions] | Computational | no | no |
| RAP1B_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NUMB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GDNF_HUMAN | [view interactions] | Computational | no | yes |
| LRP5_HUMAN | [view interactions] | Computational | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| APCL_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAH2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| IQGA1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CAMP3_HUMAN | [view interactions] | Computational | no | no |
| NPHN_HUMAN | [view interactions] | Computational | no | no |
| GNA13_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CEBPZ_HUMAN | [view interactions] | Computational | no | no |
| CTNA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GFRA1_HUMAN | [view interactions] | Computational | no | no |
| IGF2_HUMAN | [view interactions] | Computational | no | no |
| NTF2_HUMAN | [view interactions] | Computational | no | yes |
| HGF_HUMAN | [view interactions] | Computational | no | yes |
| RHG05_HUMAN | [view interactions] | Computational | no | yes |
| MYO6_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MMP3_HUMAN | [view interactions] | Computational | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ENAH_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KINH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| EXOC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CLAP2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CABL1_HUMAN | [view interactions] | Computational | no | no |
| PI51A_HUMAN | [view interactions] | Computational | no | yes |
| SNX1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |