CADH2_HUMAN
Evidence for PS localization
Functions
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells . CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CADH2_HUMAN |
|---|---|---|---|---|
| GO:0045296 | cadherin binding | 32.9412 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 30.5882 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 30.5882 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.4118 | 4 | no |
| GO:0019900 | kinase binding | 28.2353 | 4 | yes |
| GO:0019901 | protein kinase binding | 28.2353 | 5 | yes |
| GO:0046872 | metal ion binding | 17.6471 | 4 | yes |
| GO:0005509 | calcium ion binding | 9.4118 | 5 | yes |
| GO:0019902 | phosphatase binding | 9.4118 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 9.4118 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CADH2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 54.1176 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 54.1176 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 51.7647 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 48.2353 | 4 | yes |
| GO:0022607 | cellular component assembly | 44.7059 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 41.1765 | 4 | no |
| GO:0030030 | cell projection organization | 38.8235 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 36.4706 | 5 | yes |
| GO:0023056 | positive regulation of signaling | 36.4706 | 4 | yes |
| GO:0006996 | organelle organization | 35.2941 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 35.2941 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 35.2941 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 35.2941 | 4 | no |
| GO:0008104 | protein localization | 35.2941 | 4 | yes |
| GO:0031344 | regulation of cell projection organization | 35.2941 | 5 | yes |
| GO:0048584 | positive regulation of response to stimulus | 34.1176 | 4 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 32.9412 | 6 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 32.9412 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 32.9412 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 32.9412 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 32.9412 | 4 | yes |
| GO:0034330 | cell junction organization | 32.9412 | 4 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 31.7647 | 5 | yes |
| GO:0010468 | regulation of gene expression | 31.7647 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 30.5882 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 29.4118 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 29.4118 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 28.2353 | 5 | no |
| GO:0033043 | regulation of organelle organization | 28.2353 | 5 | yes |
| GO:0051049 | regulation of transport | 28.2353 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 27.0588 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 27.0588 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 27.0588 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 27.0588 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 27.0588 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 25.8824 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.8824 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 25.8824 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 25.8824 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.8824 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 25.8824 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.8824 | 5 | no |
| GO:0045216 | cell-cell junction organization | 25.8824 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 25.8824 | 4 | yes |
| GO:0030155 | regulation of cell adhesion | 24.7059 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.7059 | 4 | no |
| GO:0031399 | regulation of protein modification process | 24.7059 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 24.7059 | 6 | no |
| GO:0007010 | cytoskeleton organization | 24.7059 | 5 | no |
| GO:0032880 | regulation of protein localization | 24.7059 | 5 | yes |
| GO:0034329 | cell junction assembly | 24.7059 | 5 | yes |
| GO:2000145 | regulation of cell motility | 23.5294 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 23.5294 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.5294 | 7 | no |
| GO:0036211 | protein modification process | 23.5294 | 4 | no |
| GO:0043412 | macromolecule modification | 23.5294 | 4 | no |
| GO:0010975 | regulation of neuron projection development | 23.5294 | 7 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 22.3529 | 6 | yes |
| GO:0031175 | neuron projection development | 22.3529 | 6 | no |
| GO:0030334 | regulation of cell migration | 22.3529 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.3529 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 22.3529 | 6 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.3529 | 6 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 22.3529 | 5 | no |
| GO:0010941 | regulation of cell death | 22.3529 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 22.3529 | 8 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.3529 | 7 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 22.3529 | 4 | no |
| GO:0060284 | regulation of cell development | 21.1765 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 21.1765 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 21.1765 | 7 | no |
| GO:0051338 | regulation of transferase activity | 21.1765 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 21.1765 | 5 | yes |
| GO:0023057 | negative regulation of signaling | 21.1765 | 4 | yes |
| GO:0043408 | regulation of MAPK cascade | 21.1765 | 6 | yes |
| GO:0051050 | positive regulation of transport | 21.1765 | 4 | yes |
| GO:0048585 | negative regulation of response to stimulus | 20.0000 | 4 | yes |
| GO:0050807 | regulation of synapse organization | 20.0000 | 5 | yes |
| GO:0007043 | cell-cell junction assembly | 18.8235 | 6 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 18.8235 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 18.8235 | 4 | yes |
| GO:0009968 | negative regulation of signal transduction | 17.6471 | 5 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 17.6471 | 7 | yes |
| GO:0030111 | regulation of Wnt signaling pathway | 12.9412 | 5 | yes |
| GO:1905475 | regulation of protein localization to membrane | 11.7647 | 6 | yes |
| GO:0050808 | synapse organization | 11.7647 | 5 | yes |
| GO:0060828 | regulation of canonical Wnt signaling pathway | 11.7647 | 6 | yes |
| GO:0072657 | protein localization to membrane | 11.7647 | 4 | yes |
| GO:0030855 | epithelial cell differentiation | 10.5882 | 4 | yes |
| GO:0050770 | regulation of axonogenesis | 10.5882 | 5 | yes |
| GO:0099175 | regulation of postsynapse organization | 10.5882 | 6 | yes |
| GO:1990778 | protein localization to cell periphery | 9.4118 | 5 | yes |
| GO:0001667 | ameboidal-type cell migration | 9.4118 | 4 | yes |
| GO:0072659 | protein localization to plasma membrane | 9.4118 | 5 | yes |
| GO:2000177 | regulation of neural precursor cell proliferation | 8.2353 | 5 | yes |
| GO:0007420 | brain development | 8.2353 | 4 | yes |
| GO:0010001 | glial cell differentiation | 8.2353 | 4 | yes |
| GO:0048854 | brain morphogenesis | 7.0588 | 4 | yes |
| GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules | 7.0588 | 4 | yes |
| GO:0002064 | epithelial cell development | 5.8824 | 4 | yes |
| GO:0030178 | negative regulation of Wnt signaling pathway | 5.8824 | 6 | yes |
| GO:0048872 | homeostasis of number of cells | 5.8824 | 4 | yes |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway | 5.8824 | 7 | yes |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules | 4.7059 | 5 | yes |
| GO:0007416 | synapse assembly | 4.7059 | 6 | yes |
| GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | 4.7059 | 5 | yes |
| GO:0035994 | response to muscle stretch | 4.7059 | 4 | yes |
| GO:0043113 | receptor clustering | 4.7059 | 5 | yes |
| GO:0050982 | detection of mechanical stimulus | 4.7059 | 4 | yes |
| GO:0051966 | regulation of synaptic transmission, glutamatergic | 4.7059 | 6 | yes |
| GO:1905874 | regulation of postsynaptic density organization | 3.5294 | 6 | yes |
| GO:0002065 | columnar/cuboidal epithelial cell differentiation | 3.5294 | 5 | yes |
| GO:0002066 | columnar/cuboidal epithelial cell development | 3.5294 | 5 | yes |
| GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | 3.5294 | 5 | yes |
| GO:0035995 | detection of muscle stretch | 3.5294 | 5 | yes |
| GO:0042692 | muscle cell differentiation | 3.5294 | 4 | yes |
| GO:0044331 | cell-cell adhesion mediated by cadherin | 3.5294 | 4 | yes |
| GO:0048514 | blood vessel morphogenesis | 3.5294 | 4 | yes |
| GO:0060019 | radial glial cell differentiation | 3.5294 | 5 | yes |
| GO:0060563 | neuroepithelial cell differentiation | 3.5294 | 6 | yes |
| GO:0090497 | mesenchymal cell migration | 3.5294 | 5 | yes |
| GO:1902897 | regulation of postsynaptic density protein 95 clustering | 2.3529 | 7 | yes |
| GO:2000807 | regulation of synaptic vesicle clustering | 2.3529 | 4 | yes |
| GO:2000809 | positive regulation of synaptic vesicle clustering | 2.3529 | 5 | yes |
| GO:0002068 | glandular epithelial cell development | 2.3529 | 6 | yes |
| GO:0003323 | type B pancreatic cell development | 2.3529 | 7 | yes |
| GO:0014032 | neural crest cell development | 2.3529 | 5 | yes |
| GO:0048864 | stem cell development | 2.3529 | 4 | yes |
| GO:0051146 | striated muscle cell differentiation | 2.3529 | 5 | yes |
| GO:0070445 | regulation of oligodendrocyte progenitor proliferation | 2.3529 | 6 | yes |
| GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly | 2.3529 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in CADH2_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 2.3529 | 3 | no |
| DOID:936 | brain disease | 2.3529 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| LRP6_HUMAN | [view interactions] | Low throughput | no | yes |
| AXIN1_HUMAN | [view interactions] | Low throughput | no | yes |
| WNT3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CSK_HUMAN | [view interactions] | Low throughput | no | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NEO1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| CCNA2_HUMAN | [view interactions] | Low throughput | no | no |
| DDR1_HUMAN | [view interactions] | Low throughput | no | yes |
| EGFR_HUMAN | [view interactions] | Low throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PSN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| FGFR1_HUMAN | [view interactions] | Low throughput | no | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRF_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARVC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GNA12_HUMAN | [view interactions] | Low throughput | no | no |
| GNA13_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NHRF1_HUMAN | [view interactions] | Low throughput | no | no |
| CAD10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AKAP5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | Low throughput | no | yes |
| VANG2_HUMAN | [view interactions] | Low throughput | no | no |
| PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PTPRM_HUMAN | [view interactions] | Low throughput | no | yes |
| DDR2_HUMAN | [view interactions] | Low throughput | no | no |
| PLAK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NAA25_HUMAN | [view interactions] | Low throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDON_HUMAN | [view interactions] | Low throughput | no | no |
| GRIA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CADH2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RET_HUMAN | [view interactions] | Low throughput | no | yes |
| PKP4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTS_HUMAN | [view interactions] | Low throughput | no | no |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CAD11_HUMAN | [view interactions] | Low throughput | no | no |
| BOC_HUMAN | [view interactions] | Low throughput | no | yes |
| RHG32_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRRC7_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CADH4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| LRP5_HUMAN | [view interactions] | Low throughput | no | yes |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF3B_HUMAN | [view interactions] | High throughput | no | no |
| KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYK_HUMAN | [view interactions] | High throughput | no | no |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBSP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SKP1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAP31_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| TX1B3_HUMAN | [view interactions] | High throughput | no | no |
| SPSB4_HUMAN | [view interactions] | High throughput | no | no |
| SAPC1_HUMAN | [view interactions] | High throughput | no | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| TMPS4_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| BPNT1_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| RM23_HUMAN | [view interactions] | High throughput | no | yes |
| C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
| SSRD_HUMAN | [view interactions] | High throughput | no | yes |
| RL21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ICT1_HUMAN | [view interactions] | High throughput | no | yes |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYAG_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RM49_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM256_HUMAN | [view interactions] | High throughput | no | no |
| NENF_HUMAN | [view interactions] | High throughput | no | yes |
| SYSM_HUMAN | [view interactions] | High throughput | no | yes |
| PPT2_HUMAN | [view interactions] | High throughput | no | no |
| SYIM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NACA2_HUMAN | [view interactions] | High throughput | no | no |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| CTND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRA_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| TM11B_HUMAN | [view interactions] | High throughput | no | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| CTNA3_HUMAN | [view interactions] | High throughput | no | no |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TYRO3_HUMAN | [view interactions] | High throughput | no | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| EXOC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRC_HUMAN | [view interactions] | High throughput | no | no |
| PTPRK_HUMAN | [view interactions] | High throughput | no | no |
| PTPRG_HUMAN | [view interactions] | High throughput | no | no |
| PTPRB_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRJ_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTPRR_HUMAN | [view interactions] | High throughput | no | yes |
| PTN7_HUMAN | [view interactions] | High throughput | no | no |
| PTN6_HUMAN | [view interactions] | High throughput | no | no |
| PTN12_HUMAN | [view interactions] | High throughput | no | yes |
| PTN22_HUMAN | [view interactions] | High throughput | no | yes |
| KAP0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MET_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| RAB8B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FER_HUMAN | [view interactions] | Computational | no | yes |
| ROBO1_HUMAN | [view interactions] | Computational | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ADA10_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ZO1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MP2K6_HUMAN | [view interactions] | Computational | no | yes |
| TWST1_HUMAN | [view interactions] | Computational | no | no |
| PTN11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| RO52_HUMAN | [view interactions] | Computational | no | yes |
| PI51C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SLIT1_HUMAN | [view interactions] | Computational | no | no |
| NECT2_HUMAN | [view interactions] | Computational | no | no |
| CABL1_HUMAN | [view interactions] | Computational | no | no |
| SRC8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| DESP_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| BNIP2_HUMAN | [view interactions] | Computational | no | yes |
| SNAI1_HUMAN | [view interactions] | Computational | no | yes |
| FGFR4_HUMAN | [view interactions] | Computational | no | no |
| FINC_HUMAN | [view interactions] | Computational | no | yes |
| CTNA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| LEG3_HUMAN | [view interactions] | Computational | no | yes |
| SRC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| KINH_HUMAN | [view entry] [view interactions] | Computational | yes | no |