NTRK3_HUMAN
Evidence for PS localization
Functions
Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 93 | Thr | Met | - | - |
| 533 | Ile | Phe | - | - |
| 817 | Ile | Met | - | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NTRK3_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 26.7974 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 26.7974 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.1438 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 22.2222 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 22.2222 | 5 | yes |
| GO:0045296 | cadherin binding | 22.2222 | 4 | no |
| GO:0019900 | kinase binding | 22.2222 | 4 | no |
| GO:0005524 | ATP binding | 21.5686 | 5 | yes |
| GO:0046872 | metal ion binding | 20.9150 | 4 | no |
| GO:0019901 | protein kinase binding | 20.9150 | 5 | no |
| GO:0016301 | kinase activity | 10.4575 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 9.8039 | 4 | yes |
| GO:0004712 | protein serine/threonine/tyrosine kinase activity | 7.8431 | 4 | yes |
| GO:0004713 | protein tyrosine kinase activity | 3.2680 | 4 | yes |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity | 2.6144 | 5 | yes |
| GO:0019199 | transmembrane receptor protein kinase activity | 2.6144 | 4 | yes |
| GO:0043121 | neurotrophin binding | 1.9608 | 4 | yes |
| GO:0005003 | ephrin receptor activity | 1.3072 | 6 | yes |
| GO:0005004 | GPI-linked ephrin receptor activity | 1.3072 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NTRK3_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 53.5948 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 49.0196 | 4 | yes |
| GO:0010646 | regulation of cell communication | 47.0588 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 45.0980 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 43.1373 | 4 | yes |
| GO:0008104 | protein localization | 41.1765 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.1765 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 40.5229 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 39.2157 | 4 | yes |
| GO:0009893 | positive regulation of metabolic process | 37.9085 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.9477 | 5 | yes |
| GO:0051049 | regulation of transport | 33.9869 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.6797 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 32.6797 | 5 | yes |
| GO:0010468 | regulation of gene expression | 32.0261 | 5 | yes |
| GO:0006996 | organelle organization | 31.3725 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 30.7190 | 5 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.0654 | 5 | yes |
| GO:0071702 | organic substance transport | 29.4118 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 28.1046 | 5 | yes |
| GO:0071705 | nitrogen compound transport | 28.1046 | 4 | no |
| GO:0022607 | cellular component assembly | 27.4510 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.7974 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 26.7974 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 26.1438 | 4 | no |
| GO:0060341 | regulation of cellular localization | 26.1438 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 25.4902 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 25.4902 | 5 | no |
| GO:0032880 | regulation of protein localization | 25.4902 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.8366 | 5 | yes |
| GO:0015031 | protein transport | 24.8366 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.8366 | 6 | yes |
| GO:0023056 | positive regulation of signaling | 24.8366 | 4 | yes |
| GO:0030030 | cell projection organization | 24.1830 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 24.1830 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 24.1830 | 5 | yes |
| GO:0010941 | regulation of cell death | 24.1830 | 4 | yes |
| GO:0042127 | regulation of cell population proliferation | 24.1830 | 4 | yes |
| GO:0042325 | regulation of phosphorylation | 23.5294 | 7 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 22.8758 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.8758 | 5 | no |
| GO:0016192 | vesicle-mediated transport | 22.8758 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 22.8758 | 4 | yes |
| GO:0071310 | cellular response to organic substance | 22.2222 | 4 | yes |
| GO:0001932 | regulation of protein phosphorylation | 22.2222 | 7 | yes |
| GO:0042981 | regulation of apoptotic process | 21.5686 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 21.5686 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 21.5686 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 21.5686 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 20.9150 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.9150 | 4 | no |
| GO:0051336 | regulation of hydrolase activity | 20.2614 | 4 | yes |
| GO:0051338 | regulation of transferase activity | 20.2614 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 20.2614 | 6 | no |
| GO:0006886 | intracellular protein transport | 20.2614 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 20.2614 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.2614 | 6 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 20.2614 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 20.2614 | 5 | yes |
| GO:0031401 | positive regulation of protein modification process | 20.2614 | 7 | yes |
| GO:2000026 | regulation of multicellular organismal development | 19.6078 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 19.6078 | 4 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 18.3007 | 5 | yes |
| GO:0060548 | negative regulation of cell death | 18.3007 | 5 | yes |
| GO:0043549 | regulation of kinase activity | 18.3007 | 5 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 16.9935 | 7 | yes |
| GO:0008284 | positive regulation of cell population proliferation | 16.9935 | 5 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 16.9935 | 6 | yes |
| GO:0045859 | regulation of protein kinase activity | 16.3399 | 6 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 16.3399 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 16.3399 | 8 | yes |
| GO:0051130 | positive regulation of cellular component organization | 15.6863 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 15.6863 | 6 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 15.6863 | 8 | yes |
| GO:0010628 | positive regulation of gene expression | 15.6863 | 6 | yes |
| GO:0031344 | regulation of cell projection organization | 15.6863 | 5 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 15.0327 | 6 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 15.0327 | 4 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 15.0327 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 14.3791 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 14.3791 | 5 | yes |
| GO:2000145 | regulation of cell motility | 14.3791 | 4 | yes |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 14.3791 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 14.3791 | 5 | yes |
| GO:0051347 | positive regulation of transferase activity | 13.7255 | 5 | yes |
| GO:1901701 | cellular response to oxygen-containing compound | 13.7255 | 4 | yes |
| GO:0030334 | regulation of cell migration | 13.7255 | 5 | yes |
| GO:0043408 | regulation of MAPK cascade | 13.0719 | 6 | yes |
| GO:0060284 | regulation of cell development | 12.4183 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 12.4183 | 6 | yes |
| GO:0051093 | negative regulation of developmental process | 11.7647 | 4 | yes |
| GO:0010975 | regulation of neuron projection development | 11.7647 | 7 | yes |
| GO:0070848 | response to growth factor | 11.1111 | 4 | yes |
| GO:0071363 | cellular response to growth factor stimulus | 11.1111 | 5 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 10.4575 | 7 | yes |
| GO:0051960 | regulation of nervous system development | 10.4575 | 5 | yes |
| GO:0071900 | regulation of protein serine/threonine kinase activity | 10.4575 | 7 | yes |
| GO:2000147 | positive regulation of cell motility | 10.4575 | 5 | yes |
| GO:0030335 | positive regulation of cell migration | 10.4575 | 6 | yes |
| GO:0031400 | negative regulation of protein modification process | 10.4575 | 7 | yes |
| GO:0032970 | regulation of actin filament-based process | 10.4575 | 4 | yes |
| GO:0040017 | positive regulation of locomotion | 10.4575 | 4 | yes |
| GO:0050767 | regulation of neurogenesis | 9.8039 | 6 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 9.8039 | 6 | yes |
| GO:0032956 | regulation of actin cytoskeleton organization | 9.8039 | 5 | yes |
| GO:0045596 | negative regulation of cell differentiation | 9.8039 | 5 | yes |
| GO:0045936 | negative regulation of phosphate metabolic process | 9.1503 | 7 | yes |
| GO:0010563 | negative regulation of phosphorus metabolic process | 9.1503 | 6 | yes |
| GO:0014070 | response to organic cyclic compound | 9.1503 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 9.1503 | 4 | yes |
| GO:0042326 | negative regulation of phosphorylation | 9.1503 | 8 | yes |
| GO:0043410 | positive regulation of MAPK cascade | 9.1503 | 7 | yes |
| GO:0001933 | negative regulation of protein phosphorylation | 8.4967 | 8 | yes |
| GO:0010638 | positive regulation of organelle organization | 8.4967 | 6 | yes |
| GO:0043087 | regulation of GTPase activity | 8.4967 | 5 | yes |
| GO:0050807 | regulation of synapse organization | 7.1895 | 5 | yes |
| GO:0051495 | positive regulation of cytoskeleton organization | 7.1895 | 7 | yes |
| GO:0031346 | positive regulation of cell projection organization | 7.1895 | 6 | yes |
| GO:0071902 | positive regulation of protein serine/threonine kinase activity | 6.5359 | 8 | yes |
| GO:0050768 | negative regulation of neurogenesis | 5.8824 | 6 | yes |
| GO:0051961 | negative regulation of nervous system development | 5.8824 | 5 | yes |
| GO:0010721 | negative regulation of cell development | 5.8824 | 6 | yes |
| GO:0043547 | positive regulation of GTPase activity | 5.8824 | 6 | yes |
| GO:0051896 | regulation of protein kinase B signaling | 5.2288 | 6 | yes |
| GO:0099175 | regulation of postsynapse organization | 5.2288 | 6 | yes |
| GO:0033993 | response to lipid | 5.2288 | 4 | yes |
| GO:0043405 | regulation of MAP kinase activity | 5.2288 | 8 | yes |
| GO:0001764 | neuron migration | 4.5752 | 4 | yes |
| GO:0010976 | positive regulation of neuron projection development | 3.9216 | 7 | yes |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 3.9216 | 8 | yes |
| GO:0090630 | activation of GTPase activity | 3.2680 | 7 | yes |
| GO:0097305 | response to alcohol | 3.2680 | 4 | yes |
| GO:1901888 | regulation of cell junction assembly | 3.2680 | 5 | yes |
| GO:1990090 | cellular response to nerve growth factor stimulus | 3.2680 | 4 | yes |
| GO:2000249 | regulation of actin cytoskeleton reorganization | 3.2680 | 6 | yes |
| GO:2000251 | positive regulation of actin cytoskeleton reorganization | 3.2680 | 7 | yes |
| GO:0007507 | heart development | 3.2680 | 4 | yes |
| GO:0032103 | positive regulation of response to external stimulus | 3.2680 | 5 | yes |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 3.2680 | 9 | yes |
| GO:0043406 | positive regulation of MAP kinase activity | 3.2680 | 8 | yes |
| GO:0050920 | regulation of chemotaxis | 2.6144 | 4 | yes |
| GO:0051963 | regulation of synapse assembly | 2.6144 | 6 | yes |
| GO:0014013 | regulation of gliogenesis | 2.6144 | 7 | yes |
| GO:0032147 | activation of protein kinase activity | 2.6144 | 8 | yes |
| GO:0050921 | positive regulation of chemotaxis | 1.9608 | 5 | yes |
| GO:0071396 | cellular response to lipid | 1.9608 | 5 | yes |
| GO:1902115 | regulation of organelle assembly | 1.9608 | 5 | yes |
| GO:0045685 | regulation of glial cell differentiation | 1.9608 | 5 | yes |
| GO:0048545 | response to steroid hormone | 1.3072 | 4 | yes |
| GO:0048678 | response to axon injury | 1.3072 | 4 | yes |
| GO:0051384 | response to glucocorticoid | 1.3072 | 6 | yes |
| GO:0051385 | response to mineralocorticoid | 1.3072 | 6 | yes |
| GO:0051412 | response to corticosterone | 1.3072 | 5 | yes |
| GO:0099174 | regulation of presynapse organization | 1.3072 | 6 | yes |
| GO:1901654 | response to ketone | 1.3072 | 4 | yes |
| GO:1905606 | regulation of presynapse assembly | 1.3072 | 7 | yes |
| GO:1905874 | regulation of postsynaptic density organization | 1.3072 | 6 | yes |
| GO:0014014 | negative regulation of gliogenesis | 1.3072 | 7 | yes |
| GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling | 1.3072 | 6 | yes |
| GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | 1.3072 | 7 | yes |
| GO:0031960 | response to corticosteroid | 1.3072 | 5 | yes |
| GO:0032148 | activation of protein kinase B activity | 1.3072 | 9 | yes |
| GO:0045686 | negative regulation of glial cell differentiation | 1.3072 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in NTRK3_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 1.3072 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.3072 | 5 | no |
| DOID:114 | heart disease | 1.3072 | 3 | no |
| DOID:2843 | long QT syndrome | 1.3072 | 6 | no |
| DOID:0060038 | specific developmental disorder | 1.3072 | 3 | no |
| DOID:1059 | intellectual disability | 1.3072 | 4 | no |
| DOID:612 | primary immunodeficiency disease | 1.3072 | 3 | no |
| DOID:331 | central nervous system disease | 1.3072 | 3 | no |
| DOID:2978 | carbohydrate metabolic disorder | 1.3072 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| SORT_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| DOK6_HUMAN | [view interactions] | Low throughput | no | yes |
| MET_HUMAN | [view interactions] | Low throughput | no | yes |
| RGRF1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
| PTPRS_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NELFB_HUMAN | [view interactions] | Low throughput | no | no |
| HEY1_HUMAN | [view interactions] | Low throughput | no | yes |
| WDR13_HUMAN | [view interactions] | Low throughput | no | yes |
| IMA3_HUMAN | [view interactions] | Low throughput | no | yes |
| NSD1_HUMAN | [view interactions] | Low throughput | no | yes |
| SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SQSTM_HUMAN | [view interactions] | Low throughput | no | yes |
| ACK1_HUMAN | [view interactions] | Low throughput | no | yes |
| TNR16_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SOCS2_HUMAN | [view interactions] | Low throughput | no | yes |
| NFIP1_HUMAN | [view interactions] | Low throughput | no | yes |
| NTF3_HUMAN | [view interactions] | Low throughput | no | no |
| PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBB6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HYOU1_HUMAN | [view interactions] | High throughput | no | yes |
| RL23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS74L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCG2_HUMAN | [view interactions] | High throughput | no | yes |
| PFKAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJB11_HUMAN | [view interactions] | High throughput | no | yes |
| FANCI_HUMAN | [view interactions] | High throughput | no | yes |
| HS105_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PO210_HUMAN | [view interactions] | High throughput | no | yes |
| CDC37_HUMAN | [view interactions] | High throughput | no | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| QPCTL_HUMAN | [view interactions] | High throughput | no | yes |
| PLAL2_HUMAN | [view interactions] | High throughput | no | no |
| GDF15_HUMAN | [view interactions] | High throughput | no | no |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| TMED9_HUMAN | [view interactions] | High throughput | no | yes |
| MD2L1_HUMAN | [view interactions] | High throughput | no | no |
| TX264_HUMAN | [view interactions] | High throughput | no | no |
| RS29_HUMAN | [view interactions] | High throughput | no | yes |
| DJC10_HUMAN | [view interactions] | High throughput | no | yes |
| SCO1_HUMAN | [view interactions] | High throughput | no | yes |
| PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPYM_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGFG1_HUMAN | [view interactions] | High throughput | no | yes |
| FNBP1_HUMAN | [view interactions] | High throughput | no | yes |
| US6NL_HUMAN | [view interactions] | High throughput | no | yes |
| M21D2_HUMAN | [view interactions] | High throughput | no | yes |
| LRBA_HUMAN | [view interactions] | High throughput | no | yes |
| COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPB_HUMAN | [view interactions] | High throughput | no | yes |
| COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN13_HUMAN | [view interactions] | High throughput | no | yes |
| SC23B_HUMAN | [view interactions] | High throughput | no | yes |
| SC24B_HUMAN | [view interactions] | High throughput | no | yes |
| ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC24A_HUMAN | [view interactions] | High throughput | no | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S23IP_HUMAN | [view interactions] | High throughput | no | yes |
| COPE_HUMAN | [view interactions] | High throughput | no | yes |
| GCP60_HUMAN | [view interactions] | High throughput | no | yes |
| MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSG2_HUMAN | [view interactions] | High throughput | no | no |
| EPHA2_HUMAN | [view interactions] | High throughput | no | no |
| FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
| FERM2_HUMAN | [view interactions] | High throughput | no | yes |
| SCFD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGA_HUMAN | [view interactions] | High throughput | no | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
| S4A7_HUMAN | [view interactions] | High throughput | no | no |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
| NISCH_HUMAN | [view interactions] | High throughput | no | yes |
| NIBA2_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPON_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM1_HUMAN | [view interactions] | High throughput | no | yes |
| TRIP6_HUMAN | [view interactions] | High throughput | no | yes |
| TACC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F135A_HUMAN | [view interactions] | High throughput | no | yes |
| WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| L2GL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC4_HUMAN | [view interactions] | High throughput | no | yes |
| PKP2_HUMAN | [view interactions] | High throughput | no | yes |
| EPN4_HUMAN | [view interactions] | High throughput | no | yes |
| SERPH_HUMAN | [view interactions] | High throughput | no | no |
| BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
| NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAAT_HUMAN | [view interactions] | High throughput | no | no |
| RABL6_HUMAN | [view interactions] | High throughput | no | yes |
| ASNS_HUMAN | [view interactions] | High throughput | no | yes |
| LSR_HUMAN | [view interactions] | High throughput | no | yes |
| LIMD1_HUMAN | [view interactions] | High throughput | no | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STAM1_HUMAN | [view interactions] | High throughput | no | yes |
| M4K5_HUMAN | [view interactions] | High throughput | no | no |
| ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GGA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFG_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DIP2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OSBL8_HUMAN | [view interactions] | High throughput | no | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCC1_HUMAN | [view interactions] | High throughput | no | yes |
| CA226_HUMAN | [view interactions] | High throughput | no | yes |
| ACOT2_HUMAN | [view interactions] | High throughput | no | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAHH3_HUMAN | [view interactions] | High throughput | no | yes |
| AL3A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AAKG1_HUMAN | [view interactions] | High throughput | no | no |
| PDZ11_HUMAN | [view interactions] | High throughput | no | yes |
| KDIS_HUMAN | [view interactions] | High throughput | no | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IRAK3_HUMAN | [view interactions] | High throughput | no | yes |
| SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| WASC5_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| SYAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK5P3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDR2_HUMAN | [view interactions] | High throughput | no | no |
| PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| RHG01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SE1L1_HUMAN | [view interactions] | High throughput | no | yes |
| VANG1_HUMAN | [view interactions] | High throughput | no | no |
| S61A1_HUMAN | [view interactions] | High throughput | no | no |
| VEZA_HUMAN | [view interactions] | High throughput | no | yes |
| UNC5B_HUMAN | [view interactions] | High throughput | no | yes |
| HS905_HUMAN | [view interactions] | High throughput | no | no |
| S6A15_HUMAN | [view interactions] | High throughput | no | yes |
| ERP44_HUMAN | [view interactions] | High throughput | no | yes |
| MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HM13_HUMAN | [view interactions] | High throughput | no | yes |
| GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCRL_HUMAN | [view interactions] | High throughput | no | yes |
| ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARFG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAG6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD47_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPP2_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP1_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GORS2_HUMAN | [view interactions] | High throughput | no | yes |
| HLAC_HUMAN | [view interactions] | High throughput | no | no |
| USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDCA3_HUMAN | [view interactions] | High throughput | no | no |
| HLAA_HUMAN | [view interactions] | High throughput | no | no |
| STX5_HUMAN | [view interactions] | High throughput | no | yes |
| ERLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| ARFG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSC3_HUMAN | [view interactions] | High throughput | no | no |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLN6_HUMAN | [view interactions] | High throughput | no | no |
| PGRC2_HUMAN | [view interactions] | High throughput | no | yes |
| COCH_HUMAN | [view interactions] | High throughput | no | no |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| DNJC3_HUMAN | [view interactions] | High throughput | no | yes |
| PDXD1_HUMAN | [view interactions] | High throughput | no | no |
| ABTB1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CNPY3_HUMAN | [view interactions] | High throughput | no | yes |
| PACN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KPCI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F1712_HUMAN | [view interactions] | High throughput | no | no |
| 4F2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| OZF_HUMAN | [view interactions] | High throughput | no | yes |
| CNNM3_HUMAN | [view interactions] | High throughput | no | yes |
| SDF2L_HUMAN | [view interactions] | High throughput | no | yes |
| NUD19_HUMAN | [view interactions] | High throughput | no | no |
| NTPCR_HUMAN | [view interactions] | High throughput | no | yes |
| ERF1_HUMAN | [view interactions] | High throughput | no | yes |
| DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATS1_HUMAN | [view interactions] | High throughput | no | no |
| DIP2A_HUMAN | [view interactions] | High throughput | no | no |
| DNJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RPGF6_HUMAN | [view interactions] | High throughput | no | yes |
| FRS2_HUMAN | [view interactions] | High throughput | no | no |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFR1_HUMAN | [view interactions] | High throughput | no | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| DHB12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC115_HUMAN | [view interactions] | High throughput | no | no |
| PTK7_HUMAN | [view interactions] | High throughput | no | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MON2_HUMAN | [view interactions] | High throughput | no | no |
| LSG1_HUMAN | [view interactions] | High throughput | no | yes |
| CBPD_HUMAN | [view interactions] | High throughput | no | yes |
| EPS8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DEN4C_HUMAN | [view interactions] | High throughput | no | yes |
| AGAL_HUMAN | [view interactions] | High throughput | no | yes |
| RICTR_HUMAN | [view interactions] | High throughput | no | yes |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| TOIP1_HUMAN | [view interactions] | High throughput | no | yes |
| QSOX2_HUMAN | [view interactions] | High throughput | no | yes |
| VRK2_HUMAN | [view interactions] | High throughput | no | no |
| OST48_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FACR1_HUMAN | [view interactions] | High throughput | no | yes |
| NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACL2_HUMAN | [view interactions] | High throughput | no | yes |
| WASH6_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TB10B_HUMAN | [view interactions] | High throughput | no | no |
| CLGN_HUMAN | [view interactions] | High throughput | no | no |
| AAAS_HUMAN | [view interactions] | High throughput | no | yes |
| LTN1_HUMAN | [view interactions] | High throughput | no | no |
| NDC1_HUMAN | [view interactions] | High throughput | no | yes |
| ACSL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JPH1_HUMAN | [view interactions] | High throughput | no | no |
| PFKAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKAL_HUMAN | [view interactions] | High throughput | no | no |
| DNJA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARL1_HUMAN | [view interactions] | High throughput | no | yes |
| STIM2_HUMAN | [view interactions] | High throughput | no | yes |
| F1711_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SDF2_HUMAN | [view interactions] | High throughput | no | no |
| OSBP1_HUMAN | [view interactions] | High throughput | no | yes |
| MPRD_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPOT_HUMAN | [view interactions] | High throughput | no | no |
| GGH_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STT3B_HUMAN | [view interactions] | High throughput | no | yes |
| CDIPT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LG3BP_HUMAN | [view interactions] | High throughput | no | no |
| ARF4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
| TIMP3_HUMAN | [view interactions] | High throughput | no | no |
| MYADM_HUMAN | [view interactions] | High throughput | no | no |
| CCPG1_HUMAN | [view interactions] | High throughput | no | yes |
| C1GLT_HUMAN | [view interactions] | High throughput | no | yes |
| HAX1_HUMAN | [view interactions] | High throughput | no | no |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DGKE_HUMAN | [view interactions] | High throughput | no | yes |
| CF120_HUMAN | [view interactions] | High throughput | no | no |
| PLXB2_HUMAN | [view interactions] | High throughput | no | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG1_HUMAN | [view interactions] | High throughput | no | yes |
| DJC16_HUMAN | [view interactions] | High throughput | no | no |
| PTCD2_HUMAN | [view interactions] | High throughput | no | yes |
| HLAF_HUMAN | [view interactions] | High throughput | no | no |
| TMM11_HUMAN | [view interactions] | High throughput | no | no |
| EPCAM_HUMAN | [view interactions] | High throughput | no | no |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| ADA10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EFR3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCO2_HUMAN | [view interactions] | High throughput | no | no |
| TBC24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJB12_HUMAN | [view interactions] | High throughput | no | yes |
| GBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOGS_HUMAN | [view interactions] | High throughput | no | yes |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| HIG1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INT7_HUMAN | [view interactions] | High throughput | no | no |
| ACSL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCPP_HUMAN | [view interactions] | High throughput | no | no |
| ALG1_HUMAN | [view interactions] | High throughput | no | yes |
| MRPP3_HUMAN | [view interactions] | High throughput | no | yes |
| MAIP1_HUMAN | [view interactions] | High throughput | no | yes |
| ATP7B_HUMAN | [view interactions] | High throughput | no | no |
| STT3A_HUMAN | [view interactions] | High throughput | no | yes |
| CXCR4_HUMAN | [view interactions] | High throughput | no | no |
| TIMP1_HUMAN | [view interactions] | High throughput | no | no |
| ACD10_HUMAN | [view interactions] | High throughput | no | no |
| MAGT1_HUMAN | [view interactions] | High throughput | no | yes |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NFXL1_HUMAN | [view interactions] | High throughput | no | yes |
| EHD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRPRA_HUMAN | [view interactions] | High throughput | no | no |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| HEAT6_HUMAN | [view interactions] | High throughput | no | no |
| BAF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S39AB_HUMAN | [view interactions] | High throughput | no | no |
| SNX7_HUMAN | [view interactions] | High throughput | no | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S39A7_HUMAN | [view interactions] | High throughput | no | yes |
| THEM6_HUMAN | [view interactions] | High throughput | no | no |
| DDX58_HUMAN | [view interactions] | High throughput | no | yes |
| TECR_HUMAN | [view interactions] | High throughput | no | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUR1_HUMAN | [view interactions] | High throughput | no | yes |
| LIGO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PVR_HUMAN | [view interactions] | High throughput | no | yes |
| NEUR3_HUMAN | [view interactions] | High throughput | no | no |
| GHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACAD9_HUMAN | [view interactions] | High throughput | no | yes |
| RB39A_HUMAN | [view interactions] | High throughput | no | no |
| AT1B3_HUMAN | [view interactions] | High throughput | no | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAB45_HUMAN | [view interactions] | High throughput | no | yes |
| SHIP1_HUMAN | [view interactions] | High throughput | no | no |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| UGGG1_HUMAN | [view interactions] | High throughput | no | yes |
| AN13C_HUMAN | [view interactions] | High throughput | no | no |
| T106B_HUMAN | [view interactions] | High throughput | no | yes |
| MPRI_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAX5_HUMAN | [view interactions] | Computational | no | no |
| FRS3_HUMAN | [view interactions] | Computational | no | no |
| BDNF_HUMAN | [view interactions] | Computational | no | yes |
| SHC2_HUMAN | [view interactions] | Computational | no | yes |
| NGF_HUMAN | [view interactions] | Computational | no | no |
| TIAM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SH2B1_HUMAN | [view interactions] | Computational | no | yes |
| RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| MCF2L_HUMAN | [view interactions] | Computational | no | no |
| CRKL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MATK_HUMAN | [view interactions] | Computational | no | yes |
| SHC3_HUMAN | [view interactions] | Computational | no | yes |
| ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| PTPRO_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| BAX_HUMAN | [view interactions] | Computational | no | yes |
| RASA1_HUMAN | [view interactions] | Computational | no | yes |
| IRS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SHC4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| NTF4_HUMAN | [view interactions] | Computational | no | no |
| STAT3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RIT1_HUMAN | [view interactions] | Computational | no | yes |
| SH2B3_HUMAN | [view interactions] | Computational | no | yes |
| RIT2_HUMAN | [view interactions] | Computational | no | yes |
| SH2B2_HUMAN | [view interactions] | Computational | no | no |
| GRASP_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ETV6_HUMAN | [view interactions] | Computational | no | no |