Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

CK5P3_HUMAN

(Microbial infection) May be negatively regulated by hepatitis B virus large envelope protein mutant pre-s2 to promote mitotic entry. [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in CK5P3_HUMAN
GO:0003723 RNA binding 32.0755 4 no
GO:0017076 purine nucleotide binding 28.3019 4 no
GO:0032555 purine ribonucleotide binding 28.3019 4 no
GO:0035639 purine ribonucleoside triphosphate binding 28.3019 4 no
GO:0019900 kinase binding 22.6415 4 yes
GO:0019901 protein kinase binding 22.6415 5 yes
GO:0140297 DNA-binding transcription factor binding 11.3208 4 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9.4340 5 yes
GO:0044389 ubiquitin-like protein ligase binding 9.4340 4 yes
GO:0051059 NF-kappaB binding 5.6604 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in CK5P3_HUMAN
GO:0048522 positive regulation of cellular process 64.1509 4 yes
GO:0060255 regulation of macromolecule metabolic process 49.0566 4 yes
GO:0009893 positive regulation of metabolic process 45.2830 4 yes
GO:0008104 protein localization 45.2830 4 no
GO:0010468 regulation of gene expression 41.5094 5 yes
GO:0010646 regulation of cell communication 41.5094 4 yes
GO:0048523 negative regulation of cellular process 41.5094 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 41.5094 4 yes
GO:0080090 regulation of primary metabolic process 41.5094 4 yes
GO:0009966 regulation of signal transduction 39.6226 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 39.6226 5 yes
GO:0031323 regulation of cellular metabolic process 39.6226 4 yes
GO:0051128 regulation of cellular component organization 39.6226 4 no
GO:0006996 organelle organization 37.7358 4 no
GO:0048584 positive regulation of response to stimulus 35.8491 4 yes
GO:0051246 regulation of protein metabolic process 32.0755 5 yes
GO:0071702 organic substance transport 32.0755 4 no
GO:0071705 nitrogen compound transport 32.0755 4 no
GO:0009889 regulation of biosynthetic process 30.1887 4 yes
GO:0009892 negative regulation of metabolic process 30.1887 4 yes
GO:0010647 positive regulation of cell communication 30.1887 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 30.1887 5 yes
GO:0023056 positive regulation of signaling 30.1887 4 yes
GO:0031325 positive regulation of cellular metabolic process 30.1887 5 yes
GO:0031326 regulation of cellular biosynthetic process 30.1887 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 30.1887 5 yes
GO:0015031 protein transport 30.1887 4 no
GO:0022607 cellular component assembly 30.1887 4 no
GO:0009967 positive regulation of signal transduction 28.3019 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 28.3019 5 yes
GO:0042127 regulation of cell population proliferation 28.3019 4 no
GO:0051049 regulation of transport 28.3019 4 no
GO:0010605 negative regulation of macromolecule metabolic process 26.4151 5 yes
GO:0051252 regulation of RNA metabolic process 26.4151 5 yes
GO:0010628 positive regulation of gene expression 26.4151 6 no
GO:0071310 cellular response to organic substance 26.4151 4 no
GO:0010941 regulation of cell death 26.4151 4 no
GO:0006355 regulation of DNA-templated transcription 24.5283 6 yes
GO:0019220 regulation of phosphate metabolic process 24.5283 6 yes
GO:0031324 negative regulation of cellular metabolic process 24.5283 5 yes
GO:0042325 regulation of phosphorylation 24.5283 7 yes
GO:0051174 regulation of phosphorus metabolic process 24.5283 5 yes
GO:0051247 positive regulation of protein metabolic process 24.5283 6 yes
GO:0060341 regulation of cellular localization 24.5283 4 yes
GO:1902531 regulation of intracellular signal transduction 24.5283 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 24.5283 7 yes
GO:2001141 regulation of RNA biosynthetic process 24.5283 6 yes
GO:0006886 intracellular protein transport 24.5283 4 no
GO:0051240 positive regulation of multicellular organismal process 24.5283 4 no
GO:0042981 regulation of apoptotic process 24.5283 6 no
GO:0043067 regulation of programmed cell death 24.5283 5 no
GO:0009894 regulation of catabolic process 22.6415 4 yes
GO:0031399 regulation of protein modification process 22.6415 6 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 22.6415 5 yes
GO:0031344 regulation of cell projection organization 22.6415 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 22.6415 6 no
GO:0030334 regulation of cell migration 22.6415 5 no
GO:2000145 regulation of cell motility 22.6415 4 no
GO:0001932 regulation of protein phosphorylation 20.7547 7 yes
GO:0009891 positive regulation of biosynthetic process 20.7547 5 yes
GO:0032880 regulation of protein localization 20.7547 5 yes
GO:0043549 regulation of kinase activity 20.7547 5 yes
GO:0045595 regulation of cell differentiation 20.7547 4 yes
GO:0051338 regulation of transferase activity 20.7547 4 yes
GO:1902533 positive regulation of intracellular signal transduction 20.7547 6 yes
GO:0008284 positive regulation of cell population proliferation 20.7547 5 no
GO:0051130 positive regulation of cellular component organization 20.7547 5 no
GO:2000026 regulation of multicellular organismal development 20.7547 4 no
GO:0033365 protein localization to organelle 20.7547 5 no
GO:0044087 regulation of cellular component biogenesis 20.7547 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 18.8679 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 18.8679 6 yes
GO:0036211 protein modification process 18.8679 4 yes
GO:0043412 macromolecule modification 18.8679 4 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 18.8679 6 yes
GO:0048585 negative regulation of response to stimulus 18.8679 4 yes
GO:0010648 negative regulation of cell communication 16.9811 5 yes
GO:0023057 negative regulation of signaling 16.9811 4 yes
GO:0045859 regulation of protein kinase activity 16.9811 6 yes
GO:0051248 negative regulation of protein metabolic process 16.9811 6 yes
GO:0051336 regulation of hydrolase activity 16.9811 4 yes
GO:0051726 regulation of cell cycle 16.9811 4 yes
GO:0009968 negative regulation of signal transduction 15.0943 5 yes
GO:0051254 positive regulation of RNA metabolic process 15.0943 6 yes
GO:1903829 positive regulation of protein localization 15.0943 5 yes
GO:0010564 regulation of cell cycle process 13.2075 5 yes
GO:0031400 negative regulation of protein modification process 13.2075 7 yes
GO:0031401 positive regulation of protein modification process 13.2075 7 yes
GO:0043408 regulation of MAPK cascade 13.2075 6 yes
GO:0045893 positive regulation of DNA-templated transcription 13.2075 7 yes
GO:0071900 regulation of protein serine/threonine kinase activity 13.2075 7 yes
GO:1902680 positive regulation of RNA biosynthetic process 13.2075 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 13.2075 8 yes
GO:0006357 regulation of transcription by RNA polymerase II 11.3208 7 yes
GO:0001933 negative regulation of protein phosphorylation 9.4340 8 yes
GO:0009895 negative regulation of catabolic process 9.4340 5 yes
GO:0010563 negative regulation of phosphorus metabolic process 9.4340 6 yes
GO:0034976 response to endoplasmic reticulum stress 9.4340 4 yes
GO:0042176 regulation of protein catabolic process 9.4340 5 yes
GO:0042326 negative regulation of phosphorylation 9.4340 8 yes
GO:0043086 negative regulation of catalytic activity 9.4340 4 yes
GO:0043405 regulation of MAP kinase activity 9.4340 8 yes
GO:0045936 negative regulation of phosphate metabolic process 9.4340 7 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 9.4340 8 yes
GO:1901987 regulation of cell cycle phase transition 9.4340 6 yes
GO:1902532 negative regulation of intracellular signal transduction 9.4340 6 yes
GO:0045664 regulation of neuron differentiation 7.5472 5 yes
GO:0006469 negative regulation of protein kinase activity 5.6604 7 yes
GO:0006974 cellular response to DNA damage stimulus 5.6604 4 yes
GO:0007346 regulation of mitotic cell cycle 5.6604 5 yes
GO:0022411 cellular component disassembly 5.6604 4 yes
GO:0032446 protein modification by small protein conjugation 5.6604 6 yes
GO:0033673 negative regulation of kinase activity 5.6604 6 yes
GO:0042177 negative regulation of protein catabolic process 5.6604 6 yes
GO:0048732 gland development 5.6604 4 yes
GO:0051348 negative regulation of transferase activity 5.6604 5 yes
GO:0070647 protein modification by small protein conjugation or removal 5.6604 5 yes
GO:1901990 regulation of mitotic cell cycle phase transition 5.6604 6 yes
GO:1902749 regulation of cell cycle G2/M phase transition 5.6604 7 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 5.6604 7 yes
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 3.7736 6 yes
GO:0001889 liver development 3.7736 5 yes
GO:0007420 brain development 3.7736 4 yes
GO:0010389 regulation of G2/M transition of mitotic cell cycle 3.7736 7 yes
GO:0010948 negative regulation of cell cycle process 3.7736 6 yes
GO:0030099 myeloid cell differentiation 3.7736 4 yes
GO:0031396 regulation of protein ubiquitination 3.7736 8 yes
GO:0043409 negative regulation of MAPK cascade 3.7736 7 yes
GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation 3.7736 8 yes
GO:0045786 negative regulation of cell cycle 3.7736 5 yes
GO:0071569 protein ufmylation 3.7736 7 yes
GO:1900180 regulation of protein localization to nucleus 3.7736 6 yes
GO:1900182 positive regulation of protein localization to nucleus 3.7736 6 yes
GO:1904029 regulation of cyclin-dependent protein kinase activity 3.7736 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in CK5P3_HUMAN
DOID:0050539 Charcot-Marie-Tooth disease type 2 3.7736 7 no
DOID:10595 Charcot-Marie-Tooth disease 3.7736 6 no
DOID:331 central nervous system disease 3.7736 3 no
DOID:440 neuromuscular disease 3.7736 5 no
DOID:574 peripheral nervous system disease 3.7736 3 no
DOID:870 neuropathy 3.7736 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
UFL1_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
DDRGK_HUMAN [view entry] [view interactions] Low throughput yes yes
TX1B3_HUMAN [view interactions] Low throughput no no
HSP74_HUMAN [view entry] [view interactions] Low throughput yes yes
CADH4_HUMAN [view entry] [view interactions] Low throughput yes no
MDM2_HUMAN [view interactions] Low throughput no yes
TBG1_HUMAN [view entry] [view interactions] Low throughput yes yes
PPM1D_HUMAN [view interactions] Low throughput no no
ELAV1_HUMAN [view entry] [view interactions] Low throughput yes yes
CD5R1_HUMAN [view entry] [view interactions] Low throughput yes no
RAB9A_HUMAN [view interactions] High throughput no yes
RADI_HUMAN [view entry] [view interactions] High throughput yes yes
REEP5_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
SEC62_HUMAN [view interactions] High throughput no yes
SSRA_HUMAN [view entry] [view interactions] High throughput yes yes
STIM1_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
LAP2A_HUMAN [view interactions] High throughput no yes
TMPS2_HUMAN [view interactions] High throughput no no
FURIN_HUMAN [view interactions] High throughput no yes
DPP4_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
TM11B_HUMAN [view interactions] High throughput no no
CLC4D_HUMAN [view interactions] High throughput no no
TMPS4_HUMAN [view interactions] High throughput no yes
CLC4E_HUMAN [view interactions] High throughput no no
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
DISC1_HUMAN [view entry] [view interactions] High throughput yes no
IMA1_HUMAN [view entry] [view interactions] High throughput yes yes
ESS2_HUMAN [view interactions] High throughput no yes
TAB1_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
KI67_HUMAN [view interactions] High throughput no no
ROS1_HUMAN [view interactions] High throughput no no
UFC1_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
SPF30_HUMAN [view interactions] High throughput no no
UFM1_HUMAN [view interactions] High throughput no yes
ARL1_HUMAN [view interactions] High throughput no yes
BAF_HUMAN [view entry] [view interactions] High throughput yes yes
IGHA1_HUMAN [view entry] [view interactions] High throughput yes yes
IGKC_HUMAN [view interactions] High throughput no no
TRFL_HUMAN [view interactions] High throughput no no
OTUD4_HUMAN [view interactions] High throughput no yes
DHX36_HUMAN [view interactions] High throughput no yes
WWC3_HUMAN [view interactions] High throughput no yes
KHK_HUMAN [view interactions] High throughput no no
PLAK_HUMAN [view entry] [view interactions] High throughput yes yes
RL36_HUMAN [view entry] [view interactions] High throughput yes yes
DMBT1_HUMAN [view interactions] High throughput no no
NEP_HUMAN [view interactions] High throughput no no
HSC20_HUMAN [view interactions] High throughput no yes
FKBP6_HUMAN [view interactions] High throughput no no
TSYL4_HUMAN [view interactions] High throughput no yes
DPYL1_HUMAN [view entry] [view interactions] High throughput yes yes
SRPRB_HUMAN [view entry] [view interactions] High throughput yes no
ESR1_HUMAN [view interactions] High throughput no no
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
LAMP1_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
EPHA5_HUMAN [view interactions] High throughput no no
EPHA8_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view interactions] High throughput no yes
VGFR3_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
INSR_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
PGFRB_HUMAN [view interactions] High throughput no yes
RET_HUMAN [view interactions] High throughput no yes
ROR2_HUMAN [view entry] [view interactions] High throughput yes yes
STYK1_HUMAN [view interactions] High throughput no yes
LPD6B_HUMAN [view interactions] High throughput no no
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
PP4P2_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
PD1L1_HUMAN [view interactions] High throughput no no
TMED4_HUMAN [view interactions] High throughput no yes
PLD2_HUMAN [view interactions] High throughput no yes
TMED1_HUMAN [view interactions] High throughput no yes
PACC1_HUMAN [view interactions] High throughput no no
SIGL1_HUMAN [view interactions] High throughput no no
TMED9_HUMAN [view interactions] High throughput no yes
TRI44_HUMAN [view interactions] High throughput no yes
TPTE2_HUMAN [view interactions] High throughput no no
RT07_HUMAN [view interactions] High throughput no yes
REN3A_HUMAN [view interactions] High throughput no yes
AMTN_HUMAN [view interactions] High throughput no no
ESR2_HUMAN [view interactions] High throughput no no
TNR6A_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
TIF1B_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
SMAD4_HUMAN [view interactions] High throughput no yes
TMED5_HUMAN [view interactions] High throughput no yes
B4GN3_HUMAN [view interactions] High throughput no no
GLCE_HUMAN [view interactions] High throughput no yes
CD226_HUMAN [view interactions] High throughput no yes
SIA7F_HUMAN [view interactions] High throughput no yes
OR6T1_HUMAN [view interactions] High throughput no no
CART_HUMAN [view interactions] High throughput no yes
IRAG1_HUMAN [view interactions] High throughput no yes
EFNA4_HUMAN [view interactions] High throughput no no
XYLT1_HUMAN [view interactions] High throughput no yes
TMPSD_HUMAN [view interactions] High throughput no no
S100P_HUMAN [view interactions] High throughput no no
TMED2_HUMAN [view interactions] High throughput no yes
CMTD1_HUMAN [view entry] [view interactions] High throughput yes yes
RENT2_HUMAN [view interactions] High throughput no no
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
ZN787_HUMAN [view interactions] High throughput no yes
TMEDA_HUMAN [view interactions] High throughput no yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
CCD47_HUMAN [view interactions] High throughput no yes
NCLN_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
OTULL_HUMAN [view interactions] High throughput no no
SYVN1_HUMAN [view interactions] High throughput no yes
PDIA3_HUMAN [view entry] [view interactions] High throughput yes yes
ST7_HUMAN [view interactions] High throughput no yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
PTN1_HUMAN [view interactions] High throughput no yes
SC61B_HUMAN [view interactions] High throughput no yes
DNJC1_HUMAN [view interactions] High throughput no yes
DJC25_HUMAN [view interactions] High throughput no yes
SEC63_HUMAN [view interactions] High throughput no yes
AT2A1_HUMAN [view entry] [view interactions] High throughput yes no
B3GA1_HUMAN [view interactions] High throughput no yes
BAP31_HUMAN [view interactions] High throughput no yes
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
CXAR_HUMAN [view interactions] High throughput no yes
DERL1_HUMAN [view interactions] High throughput no yes
ELOV5_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
DHB11_HUMAN [view interactions] High throughput no yes
3BHS7_HUMAN [view interactions] High throughput no no
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
LNP_HUMAN [view interactions] High throughput no yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
MET7A_HUMAN [view interactions] High throughput no no
NU155_HUMAN [view interactions] High throughput no yes
PANX1_HUMAN [view interactions] High throughput no no
PXMP2_HUMAN [view interactions] High throughput no no
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
RAB3B_HUMAN [view interactions] High throughput no no
RAB4A_HUMAN [view entry] [view interactions] High throughput yes no
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes