IMA1_HUMAN
Evidence for PS localization
Functions
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in IMA1_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 27.3810 | 4 | yes |
| GO:0046872 | metal ion binding | 21.4286 | 4 | no |
| GO:0019900 | kinase binding | 20.2381 | 4 | no |
| GO:0019901 | protein kinase binding | 20.2381 | 5 | no |
| GO:0005048 | signal sequence binding | 8.3333 | 4 | yes |
| GO:0008139 | nuclear localization sequence binding | 7.1429 | 5 | yes |
| GO:0042826 | histone deacetylase binding | 7.1429 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in IMA1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 58.3333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 55.9524 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.9524 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 54.7619 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 53.5714 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 53.5714 | 4 | yes |
| GO:0010646 | regulation of cell communication | 44.0476 | 4 | no |
| GO:0009966 | regulation of signal transduction | 41.6667 | 4 | no |
| GO:0006996 | organelle organization | 40.4762 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 39.2857 | 4 | no |
| GO:0008104 | protein localization | 38.0952 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.0952 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 36.9048 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 36.9048 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.5238 | 5 | yes |
| GO:0010468 | regulation of gene expression | 34.5238 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 34.5238 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 34.5238 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
| GO:0036211 | protein modification process | 32.1429 | 4 | no |
| GO:0043412 | macromolecule modification | 32.1429 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 32.1429 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.1429 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 30.9524 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.9524 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 30.9524 | 5 | no |
| GO:0010941 | regulation of cell death | 29.7619 | 4 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.7619 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.5714 | 5 | no |
| GO:0015031 | protein transport | 27.3810 | 4 | yes |
| GO:0071702 | organic substance transport | 27.3810 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 27.3810 | 4 | yes |
| GO:0022607 | cellular component assembly | 27.3810 | 4 | no |
| GO:0043067 | regulation of programmed cell death | 27.3810 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.1905 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.1905 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.0000 | 5 | no |
| GO:0051726 | regulation of cell cycle | 25.0000 | 4 | no |
| GO:0033365 | protein localization to organelle | 23.8095 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 23.8095 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 23.8095 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.8095 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.8095 | 4 | no |
| GO:0007010 | cytoskeleton organization | 23.8095 | 5 | no |
| GO:0031399 | regulation of protein modification process | 23.8095 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.8095 | 6 | no |
| GO:0006886 | intracellular protein transport | 22.6190 | 4 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 22.6190 | 6 | no |
| GO:0009894 | regulation of catabolic process | 22.6190 | 4 | no |
| GO:0051049 | regulation of transport | 22.6190 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 22.6190 | 5 | no |
| GO:0023056 | positive regulation of signaling | 22.6190 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 21.4286 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.4286 | 6 | no |
| GO:0060341 | regulation of cellular localization | 21.4286 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.4286 | 5 | no |
| GO:0080134 | regulation of response to stress | 21.4286 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 20.2381 | 6 | no |
| GO:0033043 | regulation of organelle organization | 20.2381 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 20.2381 | 5 | no |
| GO:0023057 | negative regulation of signaling | 20.2381 | 4 | no |
| GO:0090304 | nucleic acid metabolic process | 17.8571 | 4 | yes |
| GO:0072594 | establishment of protein localization to organelle | 16.6667 | 4 | yes |
| GO:0006913 | nucleocytoplasmic transport | 15.4762 | 5 | yes |
| GO:0051169 | nuclear transport | 15.4762 | 4 | yes |
| GO:0034504 | protein localization to nucleus | 14.2857 | 6 | yes |
| GO:0051052 | regulation of DNA metabolic process | 14.2857 | 5 | yes |
| GO:0006606 | protein import into nucleus | 13.0952 | 5 | yes |
| GO:0051170 | import into nucleus | 13.0952 | 6 | yes |
| GO:0006259 | DNA metabolic process | 11.9048 | 4 | yes |
| GO:0000018 | regulation of DNA recombination | 7.1429 | 6 | yes |
| GO:0006607 | NLS-bearing protein import into nucleus | 5.9524 | 6 | yes |
| GO:0048524 | positive regulation of viral process | 4.7619 | 4 | yes |
| GO:0099527 | postsynapse to nucleus signaling pathway | 4.7619 | 4 | yes |
| GO:1903900 | regulation of viral life cycle | 4.7619 | 4 | yes |
| GO:0075506 | entry of viral genome into host nucleus through nuclear pore complex via importin | 2.3810 | 5 | yes |
| GO:0075732 | viral penetration into host nucleus | 2.3810 | 4 | yes |
| GO:1903902 | positive regulation of viral life cycle | 2.3810 | 5 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in IMA1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 5.9524 | 3 | no |
| DOID:1289 | neurodegenerative disease | 4.7619 | 4 | no |
| DOID:231 | motor neuron disease | 3.5714 | 5 | no |
| DOID:12377 | spinal muscular atrophy | 2.3810 | 6 | no |
| DOID:332 | amyotrophic lateral sclerosis | 2.3810 | 6 | no |
| DOID:936 | brain disease | 2.3810 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NUP50_HUMAN | [view interactions] | Low throughput | no | yes |
| KIFC1_HUMAN | [view interactions] | Low throughput | no | yes |
| ARL5A_HUMAN | [view interactions] | Low throughput | no | yes |
| EPB41_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CUL4B_HUMAN | [view interactions] | Low throughput | no | yes |
| ZN131_HUMAN | [view interactions] | Low throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | Low throughput | no | yes |
| TAF8_HUMAN | [view interactions] | Low throughput | no | yes |
| TAF3_HUMAN | [view interactions] | Low throughput | no | no |
| TIF1B_HUMAN | [view interactions] | Low throughput | no | yes |
| BAG6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | Low throughput | no | yes |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| TP53B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EP300_HUMAN | [view interactions] | Low throughput | no | yes |
| GTR2_HUMAN | [view interactions] | Low throughput | no | no |
| ABEC1_HUMAN | [view interactions] | Low throughput | no | no |
| PTMA_HUMAN | [view interactions] | Low throughput | no | yes |
| SGK1_HUMAN | [view interactions] | Low throughput | no | yes |
| LEF1_HUMAN | [view interactions] | Low throughput | no | no |
| ARL4A_HUMAN | [view interactions] | Low throughput | no | no |
| PLAG1_HUMAN | [view interactions] | Low throughput | no | no |
| PAX5_HUMAN | [view interactions] | Low throughput | no | no |
| RAG1_HUMAN | [view interactions] | Low throughput | no | no |
| NGLY1_HUMAN | [view interactions] | Low throughput | no | yes |
| TBPL2_HUMAN | [view interactions] | Low throughput | no | no |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ITK_HUMAN | [view interactions] | Low throughput | no | no |
| KC1A_HUMAN | [view interactions] | Low throughput | no | yes |
| PMS2_HUMAN | [view interactions] | Low throughput | no | yes |
| ING1_HUMAN | [view interactions] | Low throughput | no | yes |
| PCY1A_HUMAN | [view interactions] | Low throughput | no | yes |
| KAISO_HUMAN | [view interactions] | Low throughput | no | yes |
| CRY2_HUMAN | [view interactions] | Low throughput | no | yes |
| AICDA_HUMAN | [view interactions] | Low throughput | no | no |
| CHD8_HUMAN | [view interactions] | Low throughput | no | no |
| TAF10_HUMAN | [view interactions] | Low throughput | no | yes |
| IMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBP_HUMAN | [view interactions] | Low throughput | no | yes |
| KAT8_HUMAN | [view interactions] | Low throughput | no | no |
| TNR6A_HUMAN | [view interactions] | Low throughput | no | yes |
| RB_HUMAN | [view interactions] | Low throughput | no | yes |
| PHB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLS1_HUMAN | [view interactions] | Low throughput | no | no |
| PLS4_HUMAN | [view interactions] | Low throughput | no | no |
| XRCC5_HUMAN | [view interactions] | Low throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | Low throughput | no | yes |
| FEN1_HUMAN | [view interactions] | Low throughput | no | yes |
| DUT_HUMAN | [view interactions] | Low throughput | no | yes |
| SAMH1_HUMAN | [view interactions] | Low throughput | no | yes |
| PARP2_HUMAN | [view interactions] | Low throughput | no | yes |
| XRCC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERCC5_HUMAN | [view interactions] | Low throughput | no | yes |
| HNF1B_HUMAN | [view interactions] | Low throughput | no | no |
| DPOLM_HUMAN | [view interactions] | Low throughput | no | no |
| DPOLL_HUMAN | [view interactions] | Low throughput | no | no |
| GOGA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MLXPL_HUMAN | [view interactions] | Low throughput | no | no |
| HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KDM1A_HUMAN | [view interactions] | Low throughput | no | yes |
| IMB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| RECQ1_HUMAN | [view interactions] | Low throughput | no | yes |
| BCOR_HUMAN | [view interactions] | Low throughput | no | no |
| SART3_HUMAN | [view interactions] | Low throughput | no | yes |
| CHK2_HUMAN | [view interactions] | Low throughput | no | yes |
| NCBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| NCBP1_HUMAN | [view interactions] | Low throughput | no | yes |
| ANDR_HUMAN | [view interactions] | Low throughput | no | no |
| IRF3_HUMAN | [view interactions] | Low throughput | no | yes |
| XPO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SUN2_HUMAN | [view interactions] | Low throughput | no | yes |
| CDN1B_HUMAN | [view interactions] | Low throughput | no | yes |
| S10A6_HUMAN | [view interactions] | Low throughput | no | yes |
| S10A2_HUMAN | [view interactions] | Low throughput | no | no |
| MTA2_HUMAN | [view interactions] | Low throughput | no | yes |
| B2MG_HUMAN | [view interactions] | Low throughput | no | yes |
| HLAC_HUMAN | [view interactions] | Low throughput | no | no |
| KI2L2_HUMAN | [view interactions] | Low throughput | no | no |
| FOXO3_HUMAN | [view interactions] | Low throughput | no | yes |
| TPX2_HUMAN | [view interactions] | Low throughput | no | yes |
| NUMA1_HUMAN | [view interactions] | Low throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| CLIC4_HUMAN | [view interactions] | Low throughput | no | no |
| ACE2_HUMAN | [view interactions] | Low throughput | no | no |
| TF65_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBX1_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX21_HUMAN | [view interactions] | Low throughput | no | yes |
| MLH1_HUMAN | [view interactions] | Low throughput | no | yes |
| P121A_HUMAN | [view interactions] | Low throughput | no | yes |
| NMNA1_HUMAN | [view interactions] | High throughput | no | yes |
| RPAB2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| RPAB3_HUMAN | [view interactions] | High throughput | no | yes |
| SRTD3_HUMAN | [view interactions] | High throughput | no | no |
| RPAB4_HUMAN | [view interactions] | High throughput | no | no |
| PPM1G_HUMAN | [view interactions] | High throughput | no | no |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| PSME3_HUMAN | [view interactions] | High throughput | no | yes |
| MCES_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP4_HUMAN | [view interactions] | High throughput | no | yes |
| NECA2_HUMAN | [view interactions] | High throughput | no | yes |
| RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
| NF2L2_HUMAN | [view interactions] | High throughput | no | yes |
| SAE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKBB_HUMAN | [view interactions] | High throughput | no | no |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| RELB_HUMAN | [view interactions] | High throughput | no | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| NH2L1_HUMAN | [view interactions] | High throughput | no | yes |
| P5F1B_HUMAN | [view interactions] | High throughput | no | no |
| HDGF_HUMAN | [view interactions] | High throughput | no | yes |
| CD11A_HUMAN | [view interactions] | High throughput | no | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| BCL7C_HUMAN | [view interactions] | High throughput | no | yes |
| TYDP1_HUMAN | [view interactions] | High throughput | no | no |
| LN28A_HUMAN | [view interactions] | High throughput | no | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF01_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HACD3_HUMAN | [view interactions] | High throughput | no | yes |
| LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| JUPI1_HUMAN | [view interactions] | High throughput | no | yes |
| ACLY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSN4_HUMAN | [view interactions] | High throughput | no | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA7_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| HAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACO13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOMEZ_HUMAN | [view interactions] | High throughput | no | no |
| ASSY_HUMAN | [view interactions] | High throughput | no | yes |
| GMCL1_HUMAN | [view interactions] | High throughput | no | yes |
| CALX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJA4_HUMAN | [view interactions] | High throughput | no | yes |
| IDH3G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3B1_HUMAN | [view interactions] | High throughput | no | yes |
| MO4L1_HUMAN | [view interactions] | High throughput | no | yes |
| SYWC_HUMAN | [view interactions] | High throughput | no | yes |
| 4ET_HUMAN | [view interactions] | High throughput | no | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| RTRAF_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBC9_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| GBF1_HUMAN | [view interactions] | High throughput | no | yes |
| CDT1_HUMAN | [view interactions] | High throughput | no | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GPN1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN330_HUMAN | [view interactions] | High throughput | no | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| PMS1_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| CTBL1_HUMAN | [view interactions] | High throughput | no | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PRP31_HUMAN | [view interactions] | High throughput | no | yes |
| PLRG1_HUMAN | [view interactions] | High throughput | no | yes |
| SMCA4_HUMAN | [view interactions] | High throughput | no | yes |
| MO4L2_HUMAN | [view interactions] | High throughput | no | yes |
| MRGBP_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| CTCF_HUMAN | [view interactions] | High throughput | no | yes |
| SMRC2_HUMAN | [view interactions] | High throughput | no | yes |
| SMRD1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| CAH9_HUMAN | [view interactions] | High throughput | no | no |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA4_HUMAN | [view interactions] | High throughput | no | no |
| MMS19_HUMAN | [view interactions] | High throughput | no | yes |
| PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| CLK3_HUMAN | [view interactions] | High throughput | no | yes |
| SMAD6_HUMAN | [view interactions] | High throughput | no | no |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| ELF5_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MERL_HUMAN | [view interactions] | High throughput | no | yes |
| ITCH_HUMAN | [view interactions] | High throughput | no | yes |
| F204A_HUMAN | [view interactions] | High throughput | no | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PPIE_HUMAN | [view interactions] | High throughput | no | yes |
| PTC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| CHD4_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| SENP2_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| REST_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| MAGH1_HUMAN | [view interactions] | High throughput | no | yes |
| RC3H2_HUMAN | [view interactions] | High throughput | no | yes |
| CE126_HUMAN | [view interactions] | High throughput | no | no |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDIT3_HUMAN | [view interactions] | High throughput | no | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| FRIH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PUR2_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMB2_HUMAN | [view interactions] | High throughput | no | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGL2_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| FEZ2_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRAF1_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| HOME2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| MVP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| TANK_HUMAN | [view interactions] | High throughput | no | yes |
| CMTR1_HUMAN | [view interactions] | High throughput | no | yes |
| SPY1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASH2L_HUMAN | [view interactions] | High throughput | no | yes |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| MORC3_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP5_HUMAN | [view interactions] | High throughput | no | yes |
| ZBT7B_HUMAN | [view interactions] | High throughput | no | no |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| BTBD2_HUMAN | [view interactions] | High throughput | no | no |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| AKIB1_HUMAN | [view interactions] | High throughput | no | yes |
| RHG36_HUMAN | [view interactions] | High throughput | no | yes |
| COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG22_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC12A_HUMAN | [view interactions] | High throughput | no | yes |
| RHG23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK5P3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG06_HUMAN | [view interactions] | High throughput | no | yes |
| RILP_HUMAN | [view interactions] | High throughput | no | no |
| RHG09_HUMAN | [view interactions] | High throughput | no | no |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARHGG_HUMAN | [view interactions] | High throughput | no | yes |
| KLC4_HUMAN | [view interactions] | High throughput | no | yes |
| ARG39_HUMAN | [view interactions] | High throughput | no | yes |
| IFT20_HUMAN | [view interactions] | High throughput | no | yes |
| DOC11_HUMAN | [view interactions] | High throughput | no | yes |
| CC107_HUMAN | [view interactions] | High throughput | no | no |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOS2_HUMAN | [view interactions] | High throughput | no | yes |
| GT2D1_HUMAN | [view interactions] | High throughput | no | yes |
| SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
| MED19_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED9_HUMAN | [view interactions] | High throughput | no | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAP25_HUMAN | [view interactions] | High throughput | no | no |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| CBX5_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NANP8_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| RCC1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| NU153_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| STRN3_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| KIFA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| SEPT6_HUMAN | [view interactions] | High throughput | no | yes |
| SMRD3_HUMAN | [view interactions] | High throughput | no | no |
| BRD1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| RGPD5_HUMAN | [view interactions] | High throughput | no | no |
| APR_HUMAN | [view interactions] | High throughput | no | yes |
| RB39B_HUMAN | [view interactions] | High throughput | no | no |
| CDCA2_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYDE2_HUMAN | [view interactions] | High throughput | no | no |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| CTSL2_HUMAN | [view interactions] | High throughput | no | no |
| PHAX_HUMAN | [view interactions] | High throughput | no | yes |
| PPM1D_HUMAN | [view interactions] | High throughput | no | no |
| SMRD2_HUMAN | [view interactions] | High throughput | no | no |
| PDK1L_HUMAN | [view interactions] | High throughput | no | no |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| SET1A_HUMAN | [view interactions] | High throughput | no | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INT9_HUMAN | [view interactions] | High throughput | no | no |
| BCL7B_HUMAN | [view interactions] | High throughput | no | yes |
| MCE1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR1_HUMAN | [view interactions] | High throughput | no | yes |
| SNF5_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| PHF10_HUMAN | [view interactions] | High throughput | no | yes |
| SDA1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP1_HUMAN | [view interactions] | High throughput | no | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CARM1_HUMAN | [view interactions] | High throughput | no | yes |
| MBD3_HUMAN | [view interactions] | High throughput | no | yes |
| BD1L1_HUMAN | [view interactions] | High throughput | no | yes |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| RPC3_HUMAN | [view interactions] | High throughput | no | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPA34_HUMAN | [view interactions] | High throughput | no | yes |
| NOPC1_HUMAN | [view interactions] | High throughput | no | yes |
| IRF7_HUMAN | [view interactions] | High throughput | no | yes |
| ARID2_HUMAN | [view interactions] | High throughput | no | no |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| RPA49_HUMAN | [view interactions] | High throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPC7_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR2_HUMAN | [view interactions] | High throughput | no | no |
| RPC6_HUMAN | [view interactions] | High throughput | no | yes |
| DUS3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPIB6_HUMAN | [view interactions] | High throughput | no | yes |
| SH2B3_HUMAN | [view interactions] | High throughput | no | yes |
| P66A_HUMAN | [view interactions] | High throughput | no | yes |
| STAP2_HUMAN | [view interactions] | High throughput | no | yes |
| PB1_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SMRC1_HUMAN | [view interactions] | High throughput | no | yes |
| IFNG_HUMAN | [view interactions] | High throughput | no | no |
| SMCA2_HUMAN | [view interactions] | High throughput | no | yes |
| SR1IP_HUMAN | [view interactions] | High throughput | no | no |
| KI18B_HUMAN | [view interactions] | High throughput | no | no |
| S27A2_HUMAN | [view interactions] | High throughput | no | no |
| LIRB1_HUMAN | [view interactions] | High throughput | no | no |
| NEMP1_HUMAN | [view interactions] | High throughput | no | no |
| LIRB2_HUMAN | [view interactions] | High throughput | no | no |
| RGPD8_HUMAN | [view interactions] | High throughput | no | no |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| LYAR_HUMAN | [view interactions] | High throughput | no | no |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| SPRTN_HUMAN | [view interactions] | High throughput | no | yes |
| UBP11_HUMAN | [view interactions] | High throughput | no | yes |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| BAG1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK1_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANR54_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CR3L3_HUMAN | [view interactions] | High throughput | no | no |
| TAD2A_HUMAN | [view interactions] | High throughput | no | no |
| HDAC1_HUMAN | [view interactions] | High throughput | no | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| IPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| SRRT_HUMAN | [view interactions] | High throughput | no | yes |
| K1C40_HUMAN | [view interactions] | High throughput | no | no |
| NUTM1_HUMAN | [view interactions] | High throughput | no | no |
| SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
| IN80E_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| KIF22_HUMAN | [view interactions] | High throughput | no | no |
| MDFI_HUMAN | [view interactions] | High throughput | no | no |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| RBPMS_HUMAN | [view interactions] | High throughput | no | no |
| NOP58_HUMAN | [view interactions] | High throughput | no | yes |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| RPAC1_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| RPAC2_HUMAN | [view interactions] | High throughput | no | no |
| HM20A_HUMAN | [view interactions] | High throughput | no | yes |
| RPAB1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC20_HUMAN | [view interactions] | Computational | no | no |
| CCNB1_HUMAN | [view interactions] | Computational | no | no |
| PLK1_HUMAN | [view interactions] | Computational | no | yes |
| SMAD2_HUMAN | [view interactions] | Computational | no | yes |
| SERC_HUMAN | [view interactions] | Computational | no | yes |
| AGO2_HUMAN | [view interactions] | Computational | no | yes |
| KIF4A_HUMAN | [view interactions] | Computational | no | yes |
| SMAD4_HUMAN | [view interactions] | Computational | no | yes |
| AGO4_HUMAN | [view interactions] | Computational | no | no |
| TTK_HUMAN | [view interactions] | Computational | no | yes |
| AGO1_HUMAN | [view interactions] | Computational | no | no |
| NFAC1_HUMAN | [view interactions] | Computational | no | no |
| PTTG1_HUMAN | [view interactions] | Computational | no | no |
| NTF2_HUMAN | [view interactions] | Computational | no | yes |
| NU214_HUMAN | [view interactions] | Computational | no | no |
| NFAC2_HUMAN | [view interactions] | Computational | no | yes |
| UBE2C_HUMAN | [view interactions] | Computational | no | yes |
| CDK1_HUMAN | [view interactions] | Computational | no | no |
| PTN2_HUMAN | [view interactions] | Computational | no | yes |
| TXNIP_HUMAN | [view interactions] | Computational | no | no |
| TNR6C_HUMAN | [view interactions] | Computational | no | no |
| IPO5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SMAD3_HUMAN | [view interactions] | Computational | no | yes |
| AURKA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CCNB2_HUMAN | [view interactions] | Computational | no | yes |
| RAGP1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CCNA2_HUMAN | [view interactions] | Computational | no | no |
| CENPE_HUMAN | [view interactions] | Computational | no | no |
| MOV10_HUMAN | [view interactions] | Computational | no | no |
| TNR6B_HUMAN | [view interactions] | Computational | no | yes |
| NUSAP_HUMAN | [view interactions] | Computational | no | no |
| DLGP5_HUMAN | [view interactions] | Computational | no | no |
| MELK_HUMAN | [view interactions] | Computational | no | yes |
| MD2L1_HUMAN | [view interactions] | Computational | no | no |
| CKS2_HUMAN | [view interactions] | Computational | no | yes |
| TOP2A_HUMAN | [view interactions] | Computational | no | no |
| TOPK_HUMAN | [view interactions] | Computational | no | no |
| NBN_HUMAN | [view interactions] | Computational | no | yes |
| CND3_HUMAN | [view interactions] | Computational | no | yes |
| KCC4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AGO3_HUMAN | [view interactions] | Computational | no | yes |
| CDKN3_HUMAN | [view interactions] | Computational | no | no |
| NDC80_HUMAN | [view interactions] | Computational | no | no |
| PO210_HUMAN | [view interactions] | Computational | no | yes |