Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RBX1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (PubMed). The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Recruits the E2 ubiquitin-conjugating enzyme CDC34 to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

No data found.

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RBX1_HUMAN
GO:0003723 RNA binding 51.2500 4 no
GO:0000166 nucleotide binding 32.5000 4 no
GO:0017076 purine nucleotide binding 31.8750 5 no
GO:0043168 anion binding 31.8750 4 no
GO:0032555 purine ribonucleotide binding 30.6250 4 no
GO:0035639 purine ribonucleoside triphosphate binding 30.6250 4 no
GO:0030554 adenyl nucleotide binding 26.2500 6 no
GO:0005524 ATP binding 25.0000 5 no
GO:0032559 adenyl ribonucleotide binding 25.0000 5 no
GO:0043169 cation binding 17.5000 4 yes
GO:0046872 metal ion binding 17.5000 5 yes
GO:0031625 ubiquitin protein ligase binding 16.8750 5 yes
GO:0044389 ubiquitin-like protein ligase binding 16.8750 4 yes
GO:0140297 DNA-binding transcription factor binding 9.3750 4 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6.8750 5 yes
GO:0004842 ubiquitin-protein transferase activity 6.2500 4 yes
GO:0016755 aminoacyltransferase activity 6.2500 4 yes
GO:0046914 transition metal ion binding 5.0000 6 yes
GO:0008270 zinc ion binding 4.3750 7 yes
GO:0061630 ubiquitin protein ligase activity 3.7500 5 yes
GO:0061659 ubiquitin-like protein ligase activity 3.7500 4 yes
GO:0019788 NEDD8 transferase activity 1.8750 4 yes
GO:0034450 ubiquitin-ubiquitin ligase activity 1.2500 6 yes
GO:0061663 NEDD8 ligase activity 1.2500 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RBX1_HUMAN
GO:0060255 regulation of macromolecule metabolic process 47.5000 4 yes
GO:0031323 regulation of cellular metabolic process 45.6250 4 yes
GO:0048522 positive regulation of cellular process 44.3750 4 yes
GO:0080090 regulation of primary metabolic process 44.3750 4 yes
GO:0009889 regulation of biosynthetic process 42.5000 4 yes
GO:0031326 regulation of cellular biosynthetic process 42.5000 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 41.8750 5 yes
GO:0048523 negative regulation of cellular process 39.3750 4 yes
GO:0010468 regulation of gene expression 38.7500 6 yes
GO:0009893 positive regulation of metabolic process 35.0000 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 34.3750 5 yes
GO:0009059 macromolecule biosynthetic process 31.8750 4 no
GO:0009892 negative regulation of metabolic process 30.0000 4 yes
GO:0010646 regulation of cell communication 29.3750 4 yes
GO:0051246 regulation of protein metabolic process 28.7500 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.7500 5 no
GO:0031325 positive regulation of cellular metabolic process 28.7500 5 no
GO:0010605 negative regulation of macromolecule metabolic process 27.5000 5 yes
GO:0009891 positive regulation of biosynthetic process 27.5000 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.5000 6 no
GO:0022607 cellular component assembly 27.5000 4 no
GO:0031328 positive regulation of cellular biosynthetic process 27.5000 6 no
GO:0090304 nucleic acid metabolic process 26.2500 4 yes
GO:1901566 organonitrogen compound biosynthetic process 26.2500 4 no
GO:0006996 organelle organization 26.2500 4 no
GO:0009966 regulation of signal transduction 25.0000 4 yes
GO:0031324 negative regulation of cellular metabolic process 25.0000 5 yes
GO:0051252 regulation of RNA metabolic process 25.0000 5 no
GO:0051128 regulation of cellular component organization 24.3750 4 no
GO:0006412 translation 23.7500 4 no
GO:0042981 regulation of apoptotic process 23.7500 5 no
GO:0043067 regulation of programmed cell death 23.7500 4 no
GO:0002181 cytoplasmic translation 23.1250 5 no
GO:0009890 negative regulation of biosynthetic process 22.5000 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 21.8750 6 yes
GO:0006355 regulation of DNA-templated transcription 21.8750 7 no
GO:2001141 regulation of RNA biosynthetic process 21.8750 6 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.2500 6 yes
GO:0043933 protein-containing complex organization 21.2500 4 no
GO:0008104 protein localization 21.2500 4 no
GO:0048585 negative regulation of response to stimulus 20.0000 4 yes
GO:0051247 positive regulation of protein metabolic process 20.0000 6 yes
GO:0009968 negative regulation of signal transduction 18.7500 5 yes
GO:0010648 negative regulation of cell communication 18.7500 5 yes
GO:0023057 negative regulation of signaling 18.7500 4 yes
GO:1902531 regulation of intracellular signal transduction 18.7500 5 yes
GO:0009894 regulation of catabolic process 18.1250 4 yes
GO:0048584 positive regulation of response to stimulus 18.1250 4 yes
GO:0010629 negative regulation of gene expression 16.8750 7 yes
GO:0031399 regulation of protein modification process 16.8750 6 yes
GO:0043412 macromolecule modification 16.8750 4 yes
GO:0036211 protein modification process 16.2500 4 yes
GO:0009057 macromolecule catabolic process 15.0000 4 yes
GO:0009967 positive regulation of signal transduction 14.3750 5 yes
GO:0010647 positive regulation of cell communication 14.3750 5 yes
GO:0023056 positive regulation of signaling 14.3750 4 yes
GO:0006508 proteolysis 13.1250 4 yes
GO:0043687 post-translational protein modification 12.5000 5 yes
GO:0032446 protein modification by small protein conjugation 11.8750 7 yes
GO:0070647 protein modification by small protein conjugation or removal 11.8750 6 yes
GO:1902533 positive regulation of intracellular signal transduction 11.8750 6 yes
GO:0030162 regulation of proteolysis 11.2500 6 yes
GO:1901873 regulation of post-translational protein modification 11.2500 7 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 11.2500 8 yes
GO:0031396 regulation of protein ubiquitination 10.6250 9 yes
GO:0051241 negative regulation of multicellular organismal process 10.6250 4 yes
GO:1901565 organonitrogen compound catabolic process 10.6250 4 yes
GO:0016567 protein ubiquitination 10.0000 8 yes
GO:0019941 modification-dependent protein catabolic process 10.0000 6 yes
GO:0043632 modification-dependent macromolecule catabolic process 10.0000 5 yes
GO:0051603 proteolysis involved in protein catabolic process 10.0000 5 yes
GO:0006511 ubiquitin-dependent protein catabolic process 9.3750 7 yes
GO:0009896 positive regulation of catabolic process 9.3750 5 yes
GO:0001817 regulation of cytokine production 8.7500 4 yes
GO:0006259 DNA metabolic process 8.7500 5 yes
GO:0030163 protein catabolic process 8.7500 4 yes
GO:0031401 positive regulation of protein modification process 8.7500 7 yes
GO:0045862 positive regulation of proteolysis 8.7500 7 yes
GO:0042176 regulation of protein catabolic process 8.1250 5 yes
GO:0062197 cellular response to chemical stress 8.1250 4 yes
GO:0141124 intracellular signaling cassette 8.1250 4 yes
GO:0006974 DNA damage response 7.5000 4 yes
GO:0010498 proteasomal protein catabolic process 6.8750 5 yes
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 6.8750 6 yes
GO:1903050 regulation of proteolysis involved in protein catabolic process 6.8750 7 yes
GO:0061136 regulation of proteasomal protein catabolic process 6.2500 6 yes
GO:0009416 response to light stimulus 5.6250 4 yes
GO:0045732 positive regulation of protein catabolic process 5.6250 6 yes
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 5.6250 5 yes
GO:0006281 DNA repair 5.0000 5 yes
GO:0030111 regulation of Wnt signaling pathway 5.0000 5 yes
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 5.0000 6 yes
GO:1901800 positive regulation of proteasomal protein catabolic process 5.0000 7 yes
GO:1903052 positive regulation of proteolysis involved in protein catabolic process 5.0000 8 yes
GO:0000209 protein polyubiquitination 4.3750 9 yes
GO:0001818 negative regulation of cytokine production 4.3750 5 yes
GO:0031398 positive regulation of protein ubiquitination 4.3750 10 yes
GO:0042110 T cell activation 4.3750 4 yes
GO:0043122 regulation of canonical NF-kappaB signal transduction 4.3750 6 yes
GO:0043200 response to amino acid 4.3750 4 yes
GO:0060828 regulation of canonical Wnt signaling pathway 4.3750 6 yes
GO:1901875 positive regulation of post-translational protein modification 4.3750 8 yes
GO:1903322 positive regulation of protein modification by small protein conjugation or removal 4.3750 9 yes
GO:0009411 response to UV 3.7500 5 yes
GO:0030178 negative regulation of Wnt signaling pathway 3.7500 6 yes
GO:0032006 regulation of TOR signaling 3.7500 6 yes
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 3.7500 7 yes
GO:0032479 regulation of type I interferon production 3.7500 5 yes
GO:0043123 positive regulation of canonical NF-kappaB signal transduction 3.7500 7 yes
GO:0071478 cellular response to radiation 3.7500 4 yes
GO:1903432 regulation of TORC1 signaling 3.7500 7 yes
GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 3.7500 6 yes
GO:0000165 MAPK cascade 3.1250 5 yes
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3.1250 7 yes
GO:0034644 cellular response to UV 3.1250 6 yes
GO:0045116 protein neddylation 3.1250 8 yes
GO:0070936 protein K48-linked ubiquitination 3.1250 10 yes
GO:0071482 cellular response to light stimulus 3.1250 5 yes
GO:0090090 negative regulation of canonical Wnt signaling pathway 3.1250 7 yes
GO:0006513 protein monoubiquitination 2.5000 9 yes
GO:0032008 positive regulation of TOR signaling 2.5000 7 yes
GO:0032480 negative regulation of type I interferon production 2.5000 6 yes
GO:0048232 male gamete generation 2.5000 4 yes
GO:0071229 cellular response to acid chemical 2.5000 4 yes
GO:0071230 cellular response to amino acid stimulus 2.5000 5 yes
GO:1904263 positive regulation of TORC1 signaling 2.5000 8 yes
GO:0140627 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway 1.2500 7 yes
GO:1902498 regulation of protein autoubiquitination 1.2500 10 yes
GO:1902499 positive regulation of protein autoubiquitination 1.2500 11 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
MYB_HUMAN [view interactions] Low throughput no yes
UB2G2_HUMAN [view interactions] Low throughput no yes
FETUB_HUMAN [view interactions] Low throughput no no
CSN8_HUMAN [view interactions] Low throughput no yes
UB2R2_HUMAN [view interactions] Low throughput no no
UB2L3_HUMAN [view interactions] Low throughput no yes
VRK2_HUMAN [view interactions] Low throughput no no
UB2L6_HUMAN [view interactions] Low throughput no no
UB2E2_HUMAN [view interactions] Low throughput no yes
UB2E1_HUMAN [view interactions] Low throughput no yes
IMB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CCNK_HUMAN [view interactions] Low throughput no yes
UB2D4_HUMAN [view interactions] Low throughput no yes
NEUL2_HUMAN [view interactions] Low throughput no yes
UBC12_HUMAN [view entry] [view interactions] Low throughput yes yes
ERBIN_HUMAN [view entry] [view interactions] Low throughput yes yes
CFLAR_HUMAN [view interactions] Low throughput no yes
ELOF1_HUMAN [view interactions] Low throughput no yes
CSN7B_HUMAN [view interactions] Low throughput no yes
FBX11_HUMAN [view interactions] Low throughput no no
SKP2_HUMAN [view interactions] Low throughput no yes
UBXN7_HUMAN [view interactions] Low throughput no yes
CUL2_HUMAN [view interactions] Low throughput no yes
CUL3_HUMAN [view entry] [view interactions] Low throughput yes yes
CUL4A_HUMAN [view interactions] Low throughput no no
CUL5_HUMAN [view entry] [view interactions] Low throughput yes yes
VHL_HUMAN [view entry] [view interactions] Low throughput yes yes
FEM1B_HUMAN [view interactions] Low throughput no yes
CDK2_HUMAN [view interactions] Low throughput no yes
CORO7_HUMAN [view interactions] Low throughput no no
PRAME_HUMAN [view interactions] Low throughput no no
CUL4B_HUMAN [view interactions] Low throughput no yes
KLHL7_HUMAN [view interactions] Low throughput no yes
DDB1_HUMAN [view interactions] Low throughput no yes
CUL1_HUMAN [view interactions] Low throughput no yes
DTL_HUMAN [view interactions] Low throughput no no
DDB2_HUMAN [view interactions] Low throughput no yes
SESN2_HUMAN [view interactions] Low throughput no no
SESN1_HUMAN [view interactions] Low throughput no no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
KDM2B_HUMAN [view interactions] Low throughput no no
CKS1_HUMAN [view interactions] Low throughput no yes
SKP1_HUMAN [view interactions] Low throughput no yes
KBTB2_HUMAN [view interactions] Low throughput no yes
FBXL5_HUMAN [view interactions] Low throughput no yes
P85A_HUMAN [view interactions] Low throughput no yes
FBX21_HUMAN [view interactions] Low throughput no yes
KLH22_HUMAN [view interactions] Low throughput no no
MED8_HUMAN [view interactions] Low throughput no yes
FEM1C_HUMAN [view interactions] Low throughput no yes
ELOC_HUMAN [view interactions] Low throughput no no
SIL1_HUMAN [view interactions] Low throughput no yes
ELOB_HUMAN [view interactions] Low throughput no no
BRD4_HUMAN [view interactions] Low throughput no yes
CAND1_HUMAN [view entry] [view interactions] Low throughput yes no
FXL12_HUMAN [view interactions] Low throughput no yes
BECN1_HUMAN [view interactions] Low throughput no yes
CCNA2_HUMAN [view interactions] Low throughput no no
TOP2B_HUMAN [view interactions] Low throughput no yes
GLMN_HUMAN [view interactions] Low throughput no no
UB2R1_HUMAN [view interactions] Low throughput no yes
CSN5_HUMAN [view interactions] Low throughput no yes
CDN1B_HUMAN [view interactions] Low throughput no yes
CSN1_HUMAN [view interactions] Low throughput no no
CRBN_HUMAN [view interactions] Low throughput no yes
KS6B1_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAD3_HUMAN [view interactions] Low throughput no yes
MKNK2_HUMAN [view interactions] Low throughput no yes
DET1_HUMAN [view interactions] Low throughput no no
COP1_HUMAN [view interactions] Low throughput no no
CCND1_HUMAN [view interactions] Low throughput no yes
CCND2_HUMAN [view interactions] Low throughput no yes
CCND3_HUMAN [view interactions] Low throughput no no
CUL7_HUMAN [view interactions] Low throughput no yes
NEDD8_HUMAN [view entry] [view interactions] Low throughput yes yes
FBX3_HUMAN [view interactions] Low throughput no no
FBXW8_HUMAN [view interactions] Low throughput no yes
FBH1_HUMAN [view interactions] Low throughput no no
DCNL1_HUMAN [view interactions] Low throughput no yes
ABTB2_HUMAN [view interactions] Low throughput no yes
PGH2_HUMAN [view interactions] Low throughput no no
PGAM5_HUMAN [view entry] [view interactions] Low throughput yes yes
PSA6_HUMAN [view interactions] Low throughput no yes
FBX31_HUMAN [view entry] [view interactions] Low throughput yes yes
ZC3C1_HUMAN [view interactions] Low throughput no yes
KEAP1_HUMAN [view interactions] Low throughput no yes
GAN_HUMAN [view interactions] Low throughput no yes
ENC1_HUMAN [view interactions] Low throughput no no
KLH41_HUMAN [view interactions] Low throughput no no
IOD2_HUMAN [view interactions] Low throughput no no
FBW1B_HUMAN [view interactions] Low throughput no yes
CASP3_HUMAN [view entry] [view interactions] Low throughput yes yes
ING3_HUMAN [view interactions] Low throughput no no
TP4AP_HUMAN [view interactions] Low throughput no yes
FBX42_HUMAN [view interactions] Low throughput no yes
RICTR_HUMAN [view interactions] Low throughput no yes
RAG1_HUMAN [view interactions] Low throughput no no
CSN2_HUMAN [view interactions] Low throughput no yes
HXB4_HUMAN [view interactions] Low throughput no no
MCM10_HUMAN [view interactions] Low throughput no no
UB2D3_HUMAN [view interactions] Low throughput no yes
FBW1A_HUMAN [view interactions] Low throughput no yes
MCL1_HUMAN [view interactions] Low throughput no yes
CUL9_HUMAN [view interactions] Low throughput no no
FBXW2_HUMAN [view interactions] Low throughput no yes
FBX2_HUMAN [view entry] [view interactions] Low throughput yes yes
FBXW7_HUMAN [view interactions] Low throughput no yes
ERCC8_HUMAN [view interactions] Low throughput no no
FBX25_HUMAN [view interactions] Low throughput no no
CCNF_HUMAN [view interactions] Low throughput no no
PML_HUMAN [view interactions] Low throughput no yes
HINT1_HUMAN [view interactions] Low throughput no yes
CSN3_HUMAN [view entry] [view interactions] Low throughput yes yes
CSN4_HUMAN [view interactions] Low throughput no yes
CSN6_HUMAN [view interactions] Low throughput no yes
RBX1_HUMAN [view entry] [view interactions] Low throughput yes no
KLHL3_HUMAN [view interactions] Low throughput no no
SOX2_HUMAN [view interactions] Low throughput no yes
HIF1A_HUMAN [view interactions] Low throughput no no
NLRP3_HUMAN [view interactions] Low throughput no no
RHBT3_HUMAN [view interactions] Low throughput no no
MTSS1_HUMAN [view interactions] Low throughput no no
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
M4K1_HUMAN [view interactions] Low throughput no no
FXL17_HUMAN [view interactions] Low throughput no yes
STAT2_HUMAN [view interactions] Low throughput no yes
H12_HUMAN [view interactions] Low throughput no yes
DAB2P_HUMAN [view entry] [view interactions] Low throughput yes no
BACD2_HUMAN [view interactions] Low throughput no no
DCNL3_HUMAN [view interactions] Low throughput no yes
IP6K1_HUMAN [view interactions] Low throughput no yes
RHOB_HUMAN [view entry] [view interactions] Low throughput yes no
UBE2F_HUMAN [view interactions] Low throughput no yes
SAMH1_HUMAN [view interactions] Low throughput no yes
EF1A1_HUMAN [view entry] [view interactions] Low throughput yes yes
DCAF1_HUMAN [view interactions] Low throughput no yes
GATA2_HUMAN [view interactions] Low throughput no yes
MAGC2_HUMAN [view interactions] Low throughput no no
CR3L3_HUMAN [view interactions] Low throughput no no
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
FBX40_HUMAN [view interactions] Low throughput no no
KCD17_HUMAN [view interactions] Low throughput no yes
KLH18_HUMAN [view interactions] Low throughput no yes
FBX32_HUMAN [view interactions] Low throughput no no
KMT5A_HUMAN [view interactions] Low throughput no no
UBXN1_HUMAN [view interactions] Low throughput no no
CASP1_HUMAN [view interactions] Low throughput no yes
ARI1_HUMAN [view interactions] Low throughput no yes
RPB1_HUMAN [view interactions] Low throughput no no
KLDC2_HUMAN [view interactions] Low throughput no yes
ANT3_HUMAN [view interactions] Low throughput no no
PRDX2_HUMAN [view entry] [view interactions] Low throughput yes yes
FBSP1_HUMAN [view entry] [view interactions] Low throughput yes no
ATF2_HUMAN [view interactions] Low throughput no yes
ZBTB3_HUMAN [view interactions] Low throughput no yes
UBE2W_HUMAN [view interactions] Low throughput no yes
FBXL8_HUMAN [view interactions] Low throughput no yes
RASK_HUMAN [view entry] [view interactions] Low throughput yes no
UB2D1_HUMAN [view interactions] Low throughput no yes
UB2D2_HUMAN [view interactions] Low throughput no yes
UB2G1_HUMAN [view interactions] Low throughput no yes
UB2E3_HUMAN [view interactions] Low throughput no yes
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPL_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
SAFB1_HUMAN [view interactions] High throughput no yes
COXM2_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
K2C6B_HUMAN [view interactions] High throughput no no
RL13_HUMAN [view entry] [view interactions] High throughput yes yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
TBAL3_HUMAN [view interactions] High throughput no no
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
HS74L_HUMAN [view entry] [view interactions] High throughput yes no
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
CAND2_HUMAN [view entry] [view interactions] High throughput yes no
HAX1_HUMAN [view interactions] High throughput no no
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
GHR_HUMAN [view interactions] High throughput no yes
OS9_HUMAN [view interactions] High throughput no yes
HNRPF_HUMAN [view interactions] High throughput no yes
SRTD1_HUMAN [view interactions] High throughput no no
K1C16_HUMAN [view interactions] High throughput no no
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
PTBP1_HUMAN [view interactions] High throughput no no
GFPT1_HUMAN [view interactions] High throughput no no
SFRP3_HUMAN [view interactions] High throughput no no
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
LAGE3_HUMAN [view interactions] High throughput no yes
M3K7_HUMAN [view interactions] High throughput no yes
RL3_HUMAN [view entry] [view interactions] High throughput yes yes
OSGEP_HUMAN [view interactions] High throughput no yes
TAB1_HUMAN [view interactions] High throughput no yes
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
RBX2_HUMAN [view interactions] High throughput no yes
JIP2_HUMAN [view entry] [view interactions] High throughput yes no
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
UBA3_HUMAN [view interactions] High throughput no yes
M3K20_HUMAN [view interactions] High throughput no yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
CNOT1_HUMAN [view interactions] High throughput no yes
FBX33_HUMAN [view interactions] High throughput no yes
DHX15_HUMAN [view interactions] High throughput no yes
RL10_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD3_HUMAN [view interactions] High throughput no yes
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
FLNB_HUMAN [view interactions] High throughput no no
ACTBL_HUMAN [view interactions] High throughput no no
ARI2_HUMAN [view interactions] High throughput no no
CALU_HUMAN [view interactions] High throughput no yes
K1C18_HUMAN [view interactions] High throughput no no
H1T_HUMAN [view interactions] High throughput no no
IF4E_HUMAN [view entry] [view interactions] High throughput yes yes
HMGA1_HUMAN [view interactions] High throughput no yes
PLST_HUMAN [view interactions] High throughput no yes
HNRDL_HUMAN [view interactions] High throughput no yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
ELOA1_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
RO52_HUMAN [view interactions] High throughput no yes
ILF2_HUMAN [view interactions] High throughput no yes
GSTM3_HUMAN [view entry] [view interactions] High throughput yes yes
LLR1_HUMAN [view interactions] High throughput no yes
RCN2_HUMAN [view interactions] High throughput no yes
SAHH_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
MAP4_HUMAN [view entry] [view interactions] High throughput yes no
FXL15_HUMAN [view interactions] High throughput no no
RL21_HUMAN [view entry] [view interactions] High throughput yes yes
S10A2_HUMAN [view interactions] High throughput no no
RL17_HUMAN [view entry] [view interactions] High throughput yes yes
METK2_HUMAN [view interactions] High throughput no no
RGS11_HUMAN [view interactions] High throughput no yes
GARS_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
RS17_HUMAN [view entry] [view interactions] High throughput yes yes
BTD_HUMAN [view interactions] High throughput no no
RIPK4_HUMAN [view interactions] High throughput no no
ACACB_HUMAN [view interactions] High throughput no no
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
CBX3_HUMAN [view interactions] High throughput no yes
ACLY_HUMAN [view entry] [view interactions] High throughput yes yes
BTAF1_HUMAN [view interactions] High throughput no no
SYRC_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
S25A3_HUMAN [view entry] [view interactions] High throughput yes no
XPO2_HUMAN [view entry] [view interactions] High throughput yes no
NH2L1_HUMAN [view interactions] High throughput no yes
CAP1_HUMAN [view entry] [view interactions] High throughput yes yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
AIMP1_HUMAN [view interactions] High throughput no yes
ATRX_HUMAN [view entry] [view interactions] High throughput yes yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD6_HUMAN [view interactions] High throughput no yes
BRWD3_HUMAN [view interactions] High throughput no yes
RL13A_HUMAN [view entry] [view interactions] High throughput yes yes
DPYL2_HUMAN [view entry] [view interactions] High throughput yes yes
SRP72_HUMAN [view interactions] High throughput no yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
COMD1_HUMAN [view interactions] High throughput no yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
GT251_HUMAN [view interactions] High throughput no no
CSN7A_HUMAN [view interactions] High throughput no yes
SON_HUMAN [view interactions] High throughput no yes
UBP47_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
SRS10_HUMAN [view interactions] High throughput no yes
FAKD2_HUMAN [view interactions] High throughput no no
FBXW5_HUMAN [view interactions] High throughput no no
YBOX1_HUMAN [view interactions] High throughput no yes
PSD13_HUMAN [view interactions] High throughput no yes
AAAT_HUMAN [view interactions] High throughput no no
RUVB2_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
PHOCN_HUMAN [view entry] [view interactions] High throughput yes yes
INAVA_HUMAN [view interactions] High throughput no yes
DIC_HUMAN [view interactions] High throughput no yes
MIB1_HUMAN [view entry] [view interactions] High throughput yes yes
TAGL_HUMAN [view interactions] High throughput no no
BAF_HUMAN [view entry] [view interactions] High throughput yes yes
BCLF1_HUMAN [view interactions] High throughput no yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPR_HUMAN [view interactions] High throughput no yes
HP1B3_HUMAN [view interactions] High throughput no yes
KHDR1_HUMAN [view interactions] High throughput no yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
RL24_HUMAN [view entry] [view interactions] High throughput yes yes
RS18_HUMAN [view entry] [view interactions] High throughput yes yes
SUZ12_HUMAN [view interactions] High throughput no no
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
RS5_HUMAN [view entry] [view interactions] High throughput yes yes
DCAF8_HUMAN [view interactions] High throughput no yes
RS7_HUMAN [view entry] [view interactions] High throughput yes yes
SDK2_HUMAN [view interactions] High throughput no no
TRI27_HUMAN [view interactions] High throughput no yes
RN126_HUMAN [view interactions] High throughput no yes
BAG2_HUMAN [view entry] [view interactions] High throughput yes no
TRI74_HUMAN [view interactions] High throughput no no
CHTOP_HUMAN [view interactions] High throughput no yes
KR122_HUMAN [view interactions] High throughput no no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
H10_HUMAN [view interactions] High throughput no yes
PBX4_HUMAN [view interactions] High throughput no no
IF4A1_HUMAN [view interactions] High throughput no no
IF6_HUMAN [view interactions] High throughput no yes
ILF3_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
IPO4_HUMAN [view interactions] High throughput no no
MAGD1_HUMAN [view interactions] High throughput no no
PCBP2_HUMAN [view entry] [view interactions] High throughput yes yes
PININ_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
RBP2_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
RL12_HUMAN [view entry] [view interactions] High throughput yes yes
RL27A_HUMAN [view entry] [view interactions] High throughput yes yes
RL29_HUMAN [view entry] [view interactions] High throughput yes yes
RL8_HUMAN [view entry] [view interactions] High throughput yes yes
RLA1_HUMAN [view entry] [view interactions] High throughput yes no
ROA0_HUMAN [view interactions] High throughput no yes
RPB2_HUMAN [view interactions] High throughput no yes
SPB1_HUMAN [view interactions] High throughput no yes
SRSF6_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
H1X_HUMAN [view interactions] High throughput no yes
MDC1_HUMAN [view interactions] High throughput no yes
FBX22_HUMAN [view interactions] High throughput no no
NAMPT_HUMAN [view interactions] High throughput no no
TBA1B_HUMAN [view entry] [view interactions] High throughput yes yes
RAN_HUMAN [view entry] [view interactions] High throughput yes no
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
RL22_HUMAN [view entry] [view interactions] High throughput yes no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
RL23A_HUMAN [view entry] [view interactions] High throughput yes yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
RL32_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
TAF1B_HUMAN [view interactions] High throughput no no
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
THOC4_HUMAN [view interactions] High throughput no no
ZN835_HUMAN [view interactions] High throughput no no
ANO7_HUMAN [view interactions] High throughput no no
ARMC6_HUMAN [view interactions] High throughput no yes
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
CAB45_HUMAN [view interactions] High throughput no no
CGAS_HUMAN [view interactions] High throughput no yes
CREL1_HUMAN [view interactions] High throughput no yes
CSRN3_HUMAN [view interactions] High throughput no yes
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
ARI1B_HUMAN [view interactions] High throughput no yes
DSRAD_HUMAN [view entry] [view interactions] High throughput yes yes
DX39A_HUMAN [view interactions] High throughput no yes
RPGF6_HUMAN [view interactions] High throughput no yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
GANAB_HUMAN [view interactions] High throughput no yes
GL8D2_HUMAN [view interactions] High throughput no yes
GMDS_HUMAN [view interactions] High throughput no yes
GROA_HUMAN [view interactions] High throughput no no
IMA1_HUMAN [view entry] [view interactions] High throughput yes yes
ITB8_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
LRP1B_HUMAN [view interactions] High throughput no yes
MYL6_HUMAN [view entry] [view interactions] High throughput yes no
CSN9_HUMAN [view interactions] High throughput no yes
NONO_HUMAN [view interactions] High throughput no yes
NOP2_HUMAN [view interactions] High throughput no yes
NUP93_HUMAN [view interactions] High throughput no yes
RALY_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
RCN1_HUMAN [view interactions] High throughput no yes
FBX44_HUMAN [view interactions] High throughput no yes
RED1_HUMAN [view interactions] High throughput no no
FBX17_HUMAN [view interactions] High throughput no no
RINI_HUMAN [view interactions] High throughput no yes
FBX27_HUMAN [view interactions] High throughput no yes
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
RL36_HUMAN [view entry] [view interactions] High throughput yes yes
PSA2_HUMAN [view interactions] High throughput no yes
RLA2_HUMAN [view entry] [view interactions] High throughput yes yes
RNPS1_HUMAN [view interactions] High throughput no yes
RS27_HUMAN [view entry] [view interactions] High throughput yes no
RUXE_HUMAN [view interactions] High throughput no no
SHPRH_HUMAN [view interactions] High throughput no yes
SHRM4_HUMAN [view entry] [view interactions] High throughput yes yes
LRC14_HUMAN [view interactions] High throughput no no
STX6_HUMAN [view interactions] High throughput no yes
DDA1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
WDR82_HUMAN [view interactions] High throughput no no
YTHD1_HUMAN [view interactions] High throughput no no
GRK5_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
DCNL5_HUMAN [view interactions] High throughput no yes
PEBB_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
H11_HUMAN [view interactions] High throughput no no
LNP_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
RIGI_HUMAN [view interactions] High throughput no yes
APR_HUMAN [view interactions] High throughput no yes
TR10B_HUMAN [view interactions] High throughput no no
MLF2_HUMAN [view entry] [view interactions] High throughput yes yes
KBTB6_HUMAN [view interactions] High throughput no yes
HELLS_HUMAN [view interactions] High throughput no yes
KBTB7_HUMAN [view interactions] High throughput no yes
KLH24_HUMAN [view interactions] High throughput no no
IBTK_HUMAN [view interactions] High throughput no yes
KLD10_HUMAN [view interactions] High throughput no yes
KCD18_HUMAN [view interactions] High throughput no yes
LRCH3_HUMAN [view interactions] High throughput no yes
ARB2A_HUMAN [view interactions] High throughput no yes
DCNL2_HUMAN [view interactions] High throughput no yes
KCTD3_HUMAN [view interactions] High throughput no yes
DCNL4_HUMAN [view interactions] High throughput no yes
ASB3_HUMAN [view interactions] High throughput no yes
KLHL8_HUMAN [view interactions] High throughput no no
PR38A_HUMAN [view interactions] High throughput no no
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
UVRAG_HUMAN [view interactions] High throughput no yes
FBX9_HUMAN [view interactions] High throughput no no
IFIX_HUMAN [view interactions] High throughput no no
RAI14_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
FBX7_HUMAN [view interactions] High throughput no yes
DEDD_HUMAN [view interactions] High throughput no yes
KLDC3_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
CGBP1_HUMAN [view interactions] High throughput no yes
RB40C_HUMAN [view interactions] High throughput no no
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX18_HUMAN [view interactions] High throughput no no
DNM3A_HUMAN [view interactions] High throughput no yes
SHKB1_HUMAN [view interactions] High throughput no yes
SUV91_HUMAN [view interactions] High throughput no no
MYH11_HUMAN [view entry] [view interactions] High throughput yes no
CBX5_HUMAN [view interactions] High throughput no yes
BACD3_HUMAN [view interactions] High throughput no yes
KLH42_HUMAN [view interactions] High throughput no yes
MPRIP_HUMAN [view entry] [view interactions] High throughput yes yes
AHR_HUMAN [view interactions] High throughput no yes
DOCK7_HUMAN [view entry] [view interactions] High throughput yes no
MYO5B_HUMAN [view entry] [view interactions] High throughput yes yes
DCA11_HUMAN [view interactions] High throughput no yes
MYO5A_HUMAN [view entry] [view interactions] High throughput yes yes
TNIP2_HUMAN [view interactions] High throughput no yes
FBX30_HUMAN [view interactions] High throughput no yes
UTP11_HUMAN [view interactions] High throughput no yes
SPDLY_HUMAN [view interactions] High throughput no yes
BTBD9_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
MYH14_HUMAN [view entry] [view interactions] High throughput yes no
CENPW_HUMAN [view interactions] High throughput no no
ASB6_HUMAN [view interactions] High throughput no yes
AMRA1_HUMAN [view interactions] High throughput no yes
ASB7_HUMAN [view entry] [view interactions] High throughput yes yes
PHF1_HUMAN [view interactions] High throughput no yes
FBX38_HUMAN [view interactions] High throughput no yes
DCA13_HUMAN [view interactions] High throughput no yes
FXL18_HUMAN [view interactions] High throughput no no
MYO5C_HUMAN [view entry] [view interactions] High throughput yes yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
PEX6_HUMAN [view interactions] High throughput no yes
PYC_HUMAN [view entry] [view interactions] High throughput yes yes
FBX4_HUMAN [view interactions] High throughput no no
TBB5_HUMAN [view interactions] High throughput no yes
BTBD1_HUMAN [view interactions] High throughput no yes
TBB4B_HUMAN [view interactions] High throughput no yes
FBX50_HUMAN [view interactions] High throughput no no
TBA1C_HUMAN [view interactions] High throughput no yes
FBXW9_HUMAN [view interactions] High throughput no yes
H2B1C_HUMAN [view interactions] High throughput no yes
FXL14_HUMAN [view interactions] High throughput no yes
MCCB_HUMAN [view entry] [view interactions] High throughput yes yes
MCCA_HUMAN [view entry] [view interactions] High throughput yes yes
KLH13_HUMAN [view interactions] High throughput no no
TBB4A_HUMAN [view interactions] High throughput no yes
KLH15_HUMAN [view interactions] High throughput no yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
KLHL9_HUMAN [view interactions] High throughput no no
TBB2B_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC1_HUMAN [view interactions] High throughput no no
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC2_HUMAN [view interactions] High throughput no yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
HDAC3_HUMAN [view interactions] High throughput no yes
H2A2A_HUMAN [view interactions] High throughput no yes
TBL1X_HUMAN [view interactions] High throughput no yes
HNRPM_HUMAN [view entry] [view interactions] High throughput yes yes
TBL1R_HUMAN [view interactions] High throughput no yes
H2B3B_HUMAN [view interactions] High throughput no yes
MTA1_HUMAN [view interactions] High throughput no yes
PCCA_HUMAN [view entry] [view interactions] High throughput yes yes
MTA2_HUMAN [view interactions] High throughput no yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
MTA3_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
MBD3_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
SNAI1_HUMAN [view interactions] High throughput no yes
H2A1C_HUMAN [view interactions] High throughput no yes
ZEB2_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
BCAS3_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
TBB6_HUMAN [view entry] [view interactions] High throughput yes yes
PRAM2_HUMAN [view interactions] High throughput no no
DNJA1_HUMAN [view entry] [view interactions] High throughput yes yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
SIR1_HUMAN [view interactions] High throughput no yes
PCCB_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
H13_HUMAN [view interactions] High throughput no no
ZXDA_HUMAN [view interactions] High throughput no yes
DENR_HUMAN [view interactions] High throughput no yes
KCTD7_HUMAN [view interactions] High throughput no no
H2AX_HUMAN [view interactions] High throughput no yes
HNRPC_HUMAN [view interactions] High throughput no yes
NUCL_HUMAN [view interactions] High throughput no yes
SERA_HUMAN [view entry] [view interactions] High throughput yes yes
ACTC_HUMAN [view interactions] High throughput no no
ZRAN1_HUMAN [view interactions] High throughput no yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
R113A_HUMAN [view interactions] High throughput no yes
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
ADT2_HUMAN [view entry] [view interactions] High throughput yes yes
SUH_HUMAN [view interactions] High throughput no yes
DHX9_HUMAN [view interactions] High throughput no yes
MOB3C_HUMAN [view interactions] High throughput no no
H2AV_HUMAN [view interactions] High throughput no yes
SPOP_HUMAN [view interactions] High throughput no no
FBRL_HUMAN [view interactions] High throughput no yes
GOLI_HUMAN [view interactions] High throughput no yes
H2A2B_HUMAN [view interactions] High throughput no yes
H2AY_HUMAN [view interactions] High throughput no yes
LDLR_HUMAN [view interactions] High throughput no yes
VPREB_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
MATR3_HUMAN [view interactions] High throughput no yes
PRKDC_HUMAN [view entry] [view interactions] High throughput yes yes
RIT1_HUMAN [view interactions] High throughput no yes
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
LRC41_HUMAN [view interactions] High throughput no no
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes