MAP4_HUMAN
Evidence for PS localization
Functions
Non-neuronal microtubule-associated protein. Promotes microtubule assembly. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in MAP4_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 30.6452 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 27.4194 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.4194 | 4 | no |
| GO:0046872 | metal ion binding | 24.1935 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 24.1935 | 5 | no |
| GO:0005524 | ATP binding | 20.9677 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.9677 | 5 | no |
| GO:0003723 | RNA binding | 17.7419 | 4 | yes |
| GO:0015631 | tubulin binding | 16.1290 | 4 | yes |
| GO:0008017 | microtubule binding | 12.9032 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in MAP4_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 53.2258 | 4 | no |
| GO:0006996 | organelle organization | 50.0000 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 45.1613 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 43.5484 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 43.5484 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 41.9355 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 38.7097 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 38.7097 | 4 | yes |
| GO:0022607 | cellular component assembly | 37.0968 | 4 | no |
| GO:0010468 | regulation of gene expression | 35.4839 | 5 | no |
| GO:0036211 | protein modification process | 33.8710 | 4 | no |
| GO:0043412 | macromolecule modification | 33.8710 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 32.2581 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 30.6452 | 5 | no |
| GO:0010646 | regulation of cell communication | 30.6452 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.0323 | 5 | no |
| GO:0007010 | cytoskeleton organization | 27.4194 | 5 | yes |
| GO:0043933 | protein-containing complex organization | 27.4194 | 4 | no |
| GO:0009966 | regulation of signal transduction | 27.4194 | 4 | no |
| GO:0010941 | regulation of cell death | 27.4194 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 27.4194 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.4194 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 27.4194 | 5 | no |
| GO:0051049 | regulation of transport | 25.8065 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 25.8065 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 25.8065 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 25.8065 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 25.8065 | 5 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 25.8065 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.8065 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 25.8065 | 5 | no |
| GO:0033043 | regulation of organelle organization | 24.1935 | 5 | yes |
| GO:0044087 | regulation of cellular component biogenesis | 24.1935 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 24.1935 | 5 | no |
| GO:0071310 | cellular response to organic substance | 24.1935 | 4 | no |
| GO:0008104 | protein localization | 22.5806 | 4 | no |
| GO:0009894 | regulation of catabolic process | 20.9677 | 4 | no |
| GO:0031399 | regulation of protein modification process | 20.9677 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 20.9677 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.9677 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 20.9677 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 20.9677 | 5 | no |
| GO:0031344 | regulation of cell projection organization | 16.1290 | 5 | yes |
| GO:0051129 | negative regulation of cellular component organization | 16.1290 | 5 | yes |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 16.1290 | 6 | yes |
| GO:0030030 | cell projection organization | 14.5161 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 14.5161 | 5 | yes |
| GO:0031175 | neuron projection development | 9.6774 | 6 | yes |
| GO:0010639 | negative regulation of organelle organization | 8.0645 | 6 | yes |
| GO:0060491 | regulation of cell projection assembly | 8.0645 | 5 | yes |
| GO:0120032 | regulation of plasma membrane bounded cell projection assembly | 8.0645 | 6 | yes |
| GO:1902115 | regulation of organelle assembly | 8.0645 | 5 | yes |
| GO:1902850 | microtubule cytoskeleton organization involved in mitosis | 6.4516 | 4 | yes |
| GO:0007052 | mitotic spindle organization | 4.8387 | 4 | yes |
| GO:0031345 | negative regulation of cell projection organization | 4.8387 | 6 | yes |
| GO:0051293 | establishment of spindle localization | 4.8387 | 4 | yes |
| GO:0051294 | establishment of spindle orientation | 4.8387 | 5 | yes |
| GO:1902017 | regulation of cilium assembly | 4.8387 | 6 | yes |
| GO:1902116 | negative regulation of organelle assembly | 3.2258 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in MAP4_HUMAN |
|---|---|---|---|---|
| DOID:0050700 | cardiomyopathy | 3.2258 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.2258 | 5 | no |
| DOID:114 | heart disease | 3.2258 | 3 | no |
| DOID:331 | central nervous system disease | 3.2258 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MARK4_HUMAN | [view interactions] | Low throughput | no | yes |
| CDK1_HUMAN | [view interactions] | Low throughput | no | no |
| MARK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ULK1_HUMAN | [view interactions] | Low throughput | no | no |
| KC1D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| UBP21_HUMAN | [view interactions] | Low throughput | no | no |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| BMP4_HUMAN | [view interactions] | High throughput | no | no |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| AAR2_HUMAN | [view interactions] | High throughput | no | no |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FGF11_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BACH1_HUMAN | [view interactions] | High throughput | no | no |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANO7_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| NGB_HUMAN | [view interactions] | High throughput | no | yes |
| ACK1_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| EMC2_HUMAN | [view interactions] | High throughput | no | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP10_HUMAN | [view interactions] | High throughput | no | yes |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| CAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| KCNA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLU_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBX1_HUMAN | [view interactions] | High throughput | no | yes |
| EPN4_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| EPN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| PDZ11_HUMAN | [view interactions] | High throughput | no | yes |
| MA7D1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CKP2L_HUMAN | [view interactions] | High throughput | no | yes |
| MCM10_HUMAN | [view interactions] | High throughput | no | no |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PFD3_HUMAN | [view interactions] | High throughput | no | yes |
| SSBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF22_HUMAN | [view interactions] | High throughput | no | no |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
| CKAP2_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF2C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PFD5_HUMAN | [view interactions] | High throughput | no | yes |
| SPAG5_HUMAN | [view interactions] | High throughput | no | yes |
| PEO1_HUMAN | [view interactions] | High throughput | no | yes |
| TBCD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPRY3_HUMAN | [view interactions] | High throughput | no | yes |
| BCKD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLTM_HUMAN | [view interactions] | High throughput | no | yes |
| CP131_HUMAN | [view interactions] | High throughput | no | no |
| NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
| PABP2_HUMAN | [view interactions] | High throughput | no | yes |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| FA83D_HUMAN | [view interactions] | High throughput | no | no |
| SLAI1_HUMAN | [view interactions] | High throughput | no | no |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BLM_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD52_HUMAN | [view interactions] | High throughput | no | no |
| CP110_HUMAN | [view interactions] | High throughput | no | yes |
| WDR62_HUMAN | [view interactions] | High throughput | no | no |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| TACC2_HUMAN | [view interactions] | High throughput | no | yes |
| MABP1_HUMAN | [view interactions] | High throughput | no | yes |
| PDZD8_HUMAN | [view interactions] | High throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO2_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IL7RA_HUMAN | [view interactions] | High throughput | no | no |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
| COG7_HUMAN | [view interactions] | High throughput | no | yes |
| CSTF2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| SYIC_HUMAN | [view interactions] | High throughput | no | yes |
| MTA2_HUMAN | [view interactions] | High throughput | no | yes |
| RPB1_HUMAN | [view interactions] | High throughput | no | no |
| RPB3_HUMAN | [view interactions] | High throughput | no | yes |
| PP4R1_HUMAN | [view interactions] | High throughput | no | yes |
| WDHD1_HUMAN | [view interactions] | High throughput | no | no |
| LSM8_HUMAN | [view interactions] | High throughput | no | yes |
| PDCD6_HUMAN | [view interactions] | High throughput | no | no |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| LSM3_HUMAN | [view interactions] | High throughput | no | yes |
| LASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAIRB_HUMAN | [view interactions] | High throughput | no | yes |
| SLK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DCA15_HUMAN | [view interactions] | High throughput | no | no |
| RHBL4_HUMAN | [view interactions] | High throughput | no | no |
| CHTOP_HUMAN | [view interactions] | High throughput | no | yes |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI36_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FYCO1_HUMAN | [view interactions] | High throughput | no | no |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| NEK4_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| H15_HUMAN | [view interactions] | High throughput | no | no |
| MIC60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PHAG1_HUMAN | [view interactions] | High throughput | no | yes |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RD3_HUMAN | [view interactions] | High throughput | no | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| ENOG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| RB22A_HUMAN | [view interactions] | High throughput | no | yes |
| RB40B_HUMAN | [view interactions] | High throughput | no | no |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| POTE1_HUMAN | [view interactions] | High throughput | no | no |
| NR1I3_HUMAN | [view interactions] | High throughput | no | no |
| RXRB_HUMAN | [view interactions] | High throughput | no | yes |
| RXRG_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOP58_HUMAN | [view interactions] | High throughput | no | yes |
| STRBP_HUMAN | [view interactions] | High throughput | no | yes |
| CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDGF_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXP3_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| BAG3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF11_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| MARK3_HUMAN | [view interactions] | Computational | no | yes |