CNTP2_HUMAN
Evidence for PS localization
Functions
Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CNTP2_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 25.0000 | 4 | no |
| GO:0000166 | nucleotide binding | 23.0000 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.0000 | 5 | no |
| GO:0043169 | cation binding | 23.0000 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 22.0000 | 4 | no |
| GO:0046872 | metal ion binding | 22.0000 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.0000 | 4 | no |
| GO:0002020 | protease binding | 3.0000 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CNTP2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 47.0000 | 4 | yes |
| GO:0010646 | regulation of cell communication | 38.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 37.0000 | 4 | yes |
| GO:0008104 | protein localization | 34.0000 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 33.0000 | 4 | no |
| GO:0022607 | cellular component assembly | 32.0000 | 4 | no |
| GO:0006996 | organelle organization | 32.0000 | 4 | no |
| GO:0051049 | regulation of transport | 28.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 27.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 26.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 24.0000 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.0000 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 23.0000 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 23.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 23.0000 | 4 | no |
| GO:0030030 | cell projection organization | 22.0000 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 21.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 21.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 21.0000 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 20.0000 | 4 | yes |
| GO:0051130 | positive regulation of cellular component organization | 18.0000 | 5 | yes |
| GO:0048812 | neuron projection morphogenesis | 15.0000 | 5 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 15.0000 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 15.0000 | 4 | yes |
| GO:0031175 | neuron projection development | 14.0000 | 6 | yes |
| GO:0048585 | negative regulation of response to stimulus | 13.0000 | 4 | yes |
| GO:0050890 | cognition | 12.0000 | 4 | yes |
| GO:0061024 | membrane organization | 11.0000 | 4 | yes |
| GO:0007612 | learning | 10.0000 | 4 | yes |
| GO:0032101 | regulation of response to external stimulus | 9.0000 | 4 | yes |
| GO:1901888 | regulation of cell junction assembly | 9.0000 | 5 | yes |
| GO:0044089 | positive regulation of cellular component biogenesis | 8.0000 | 5 | yes |
| GO:0007420 | brain development | 6.0000 | 4 | yes |
| GO:0071205 | protein localization to juxtaparanode region of axon | 5.0000 | 6 | yes |
| GO:0099612 | protein localization to axon | 5.0000 | 5 | yes |
| GO:1901890 | positive regulation of cell junction assembly | 5.0000 | 6 | yes |
| GO:0032102 | negative regulation of response to external stimulus | 4.0000 | 5 | yes |
| GO:0045161 | neuronal ion channel clustering | 3.0000 | 5 | yes |
| GO:0045163 | clustering of voltage-gated potassium channels | 3.0000 | 6 | yes |
| GO:0098597 | observational learning | 3.0000 | 5 | yes |
| GO:0019226 | transmission of nerve impulse | 2.0000 | 4 | yes |
| GO:0021761 | limbic system development | 2.0000 | 4 | yes |
| GO:0031223 | auditory behavior | 2.0000 | 4 | yes |
| GO:0042297 | vocal learning | 2.0000 | 5 | yes |
| GO:0060134 | prepulse inhibition | 2.0000 | 6 | yes |
| GO:0098596 | imitative learning | 2.0000 | 6 | yes |
| GO:0098598 | learned vocalization behavior or vocal learning | 2.0000 | 4 | yes |
| GO:1903596 | regulation of gap junction assembly | 2.0000 | 6 | yes |
| GO:1903598 | positive regulation of gap junction assembly | 2.0000 | 7 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSKP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BIP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDIA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CNTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CBPE_HUMAN | [view interactions] | Low throughput | no | yes |
| CNTN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KCNA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MPP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E41L3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GPR37_HUMAN | [view interactions] | Low throughput | no | no |
| GABR2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLPR3_HUMAN | [view interactions] | High throughput | no | no |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| PSD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN2_HUMAN | [view interactions] | High throughput | no | yes |
| RAB6B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP2_HUMAN | [view interactions] | High throughput | no | yes |
| RAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUFY3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3G1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S4A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| S4A8_HUMAN | [view interactions] | High throughput | no | no |
| SLIK5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNP25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| STAU2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STIM2_HUMAN | [view interactions] | High throughput | no | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STX1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SVOP_HUMAN | [view interactions] | High throughput | no | no |
| SYN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYT11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCAL6_HUMAN | [view interactions] | High throughput | no | no |
| TCAL5_HUMAN | [view interactions] | High throughput | no | no |
| TEN1_HUMAN | [view interactions] | High throughput | no | no |
| TEN4_HUMAN | [view interactions] | High throughput | no | no |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| TXNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP2L_HUMAN | [view interactions] | High throughput | no | yes |
| WNK2_HUMAN | [view interactions] | High throughput | no | yes |
| YKT6_HUMAN | [view interactions] | High throughput | no | yes |
| ZDBF2_HUMAN | [view interactions] | High throughput | no | yes |
| CTR9_HUMAN | [view interactions] | High throughput | no | yes |
| ZMIZ1_HUMAN | [view interactions] | High throughput | no | no |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| RPB7_HUMAN | [view interactions] | High throughput | no | yes |
| GORS2_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KCAB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCND3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCIP2_HUMAN | [view interactions] | High throughput | no | no |
| KCNQ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT3_HUMAN | [view interactions] | High throughput | no | no |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SMAP_HUMAN | [view interactions] | High throughput | no | yes |
| ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ADDG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGRL1_HUMAN | [view interactions] | High throughput | no | no |
| AGRL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMER2_HUMAN | [view interactions] | High throughput | no | yes |
| APBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AQP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARF5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARFG1_HUMAN | [view interactions] | High throughput | no | no |
| AT2C1_HUMAN | [view interactions] | High throughput | no | yes |
| BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CACB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSKI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CKAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CXAR_HUMAN | [view interactions] | High throughput | no | yes |
| CYH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX29_HUMAN | [view interactions] | High throughput | no | yes |
| EDC4_HUMAN | [view interactions] | High throughput | no | yes |
| EF1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
| EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F131B_HUMAN | [view interactions] | High throughput | no | no |
| F1712_HUMAN | [view interactions] | High throughput | no | no |
| F171B_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GGT7_HUMAN | [view interactions] | High throughput | no | yes |
| MGLYR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
| H15_HUMAN | [view interactions] | High throughput | no | no |
| H2A2A_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1D_HUMAN | [view interactions] | High throughput | no | yes |
| H2AJ_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1A_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| H2A3_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1J_HUMAN | [view interactions] | High throughput | no | yes |
| H2AX_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1C_HUMAN | [view interactions] | High throughput | no | yes |
| H2A2C_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1H_HUMAN | [view interactions] | High throughput | no | yes |
| HS12A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IGSF3_HUMAN | [view interactions] | High throughput | no | yes |
| KCNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCAB1_HUMAN | [view interactions] | High throughput | no | no |
| KCND2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNH7_HUMAN | [view interactions] | High throughput | no | no |
| KCNQ3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MON2_HUMAN | [view interactions] | High throughput | no | no |
| NAMPT_HUMAN | [view interactions] | High throughput | no | no |
| NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NDUS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NECT1_HUMAN | [view interactions] | High throughput | no | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OGFR_HUMAN | [view interactions] | High throughput | no | yes |
| PAK3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PALM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PANX2_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PCDA4_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |