AGAP2_HUMAN
Evidence for PS localization
Functions
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AGAP2_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 29.4798 | 4 | yes |
| GO:0032555 | purine ribonucleotide binding | 29.4798 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.7457 | 4 | yes |
| GO:0046872 | metal ion binding | 26.5896 | 4 | yes |
| GO:0019900 | kinase binding | 21.9653 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 21.9653 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 21.9653 | 5 | yes |
| GO:0005524 | ATP binding | 20.2312 | 5 | yes |
| GO:0019901 | protein kinase binding | 19.6532 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 13.8728 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 10.4046 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 10.4046 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 10.4046 | 6 | yes |
| GO:0003924 | GTPase activity | 9.8266 | 7 | yes |
| GO:0005096 | GTPase activator activity | 9.2486 | 4 | yes |
| GO:0019001 | guanyl nucleotide binding | 8.6705 | 5 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 8.6705 | 5 | yes |
| GO:0005525 | GTP binding | 8.0925 | 5 | yes |
| GO:0019887 | protein kinase regulator activity | 5.2023 | 4 | yes |
| GO:0019209 | kinase activator activity | 2.8902 | 4 | yes |
| GO:0030295 | protein kinase activator activity | 2.8902 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AGAP2_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 57.8035 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 56.0694 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 49.7110 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 45.0867 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 43.9306 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 41.6185 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 36.9942 | 4 | yes |
| GO:0051049 | regulation of transport | 36.4162 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 35.8382 | 4 | yes |
| GO:0006996 | organelle organization | 34.1040 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 34.1040 | 4 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 32.3699 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 32.3699 | 4 | no |
| GO:0022607 | cellular component assembly | 31.2139 | 4 | no |
| GO:0008104 | protein localization | 30.6358 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 30.0578 | 5 | no |
| GO:0023056 | positive regulation of signaling | 30.0578 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 28.3237 | 5 | yes |
| GO:0010468 | regulation of gene expression | 27.7457 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.7457 | 4 | no |
| GO:0030030 | cell projection organization | 27.7457 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 26.5896 | 4 | yes |
| GO:0033043 | regulation of organelle organization | 26.0116 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 26.0116 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.4335 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 25.4335 | 5 | yes |
| GO:0022603 | regulation of anatomical structure morphogenesis | 24.8555 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.2775 | 5 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 23.6994 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 23.6994 | 5 | no |
| GO:0036211 | protein modification process | 22.5434 | 4 | no |
| GO:0043412 | macromolecule modification | 22.5434 | 4 | no |
| GO:0060341 | regulation of cellular localization | 22.5434 | 4 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.5434 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 22.5434 | 5 | no |
| GO:0071702 | organic substance transport | 21.9653 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 21.9653 | 4 | yes |
| GO:0045595 | regulation of cell differentiation | 21.9653 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.9653 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 21.9653 | 4 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 21.3873 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 21.3873 | 5 | yes |
| GO:0009889 | regulation of biosynthetic process | 20.8092 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 20.8092 | 4 | yes |
| GO:0019220 | regulation of phosphate metabolic process | 20.8092 | 6 | yes |
| GO:0031399 | regulation of protein modification process | 20.8092 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 20.8092 | 5 | yes |
| GO:0051050 | positive regulation of transport | 20.2312 | 4 | no |
| GO:0034330 | cell junction organization | 20.2312 | 4 | no |
| GO:0043269 | regulation of ion transport | 20.2312 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 20.2312 | 5 | yes |
| GO:0042325 | regulation of phosphorylation | 19.6532 | 7 | yes |
| GO:0043085 | positive regulation of catalytic activity | 19.6532 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 19.0751 | 5 | yes |
| GO:0001932 | regulation of protein phosphorylation | 18.4971 | 7 | yes |
| GO:0010941 | regulation of cell death | 18.4971 | 4 | yes |
| GO:0015031 | protein transport | 18.4971 | 4 | yes |
| GO:0051247 | positive regulation of protein metabolic process | 18.4971 | 6 | yes |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 17.3410 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 16.7630 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 16.7630 | 5 | yes |
| GO:0051338 | regulation of transferase activity | 15.6069 | 4 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 14.4509 | 6 | yes |
| GO:0042327 | positive regulation of phosphorylation | 14.4509 | 8 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 14.4509 | 7 | yes |
| GO:0001934 | positive regulation of protein phosphorylation | 13.8728 | 8 | yes |
| GO:0031401 | positive regulation of protein modification process | 13.8728 | 7 | yes |
| GO:0043549 | regulation of kinase activity | 13.8728 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 13.2948 | 4 | yes |
| GO:0045859 | regulation of protein kinase activity | 13.2948 | 6 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 13.2948 | 6 | yes |
| GO:0051347 | positive regulation of transferase activity | 11.5607 | 5 | yes |
| GO:0033674 | positive regulation of kinase activity | 10.4046 | 6 | yes |
| GO:0045860 | positive regulation of protein kinase activity | 9.8266 | 7 | yes |
| GO:0060548 | negative regulation of cell death | 9.8266 | 5 | yes |
| GO:1901214 | regulation of neuron death | 9.2486 | 5 | yes |
| GO:0043066 | negative regulation of apoptotic process | 8.6705 | 7 | yes |
| GO:0043069 | negative regulation of programmed cell death | 8.6705 | 6 | yes |
| GO:1901215 | negative regulation of neuron death | 6.9364 | 6 | yes |
| GO:0042176 | regulation of protein catabolic process | 6.9364 | 5 | yes |
| GO:0009895 | negative regulation of catabolic process | 6.3584 | 5 | yes |
| GO:0043523 | regulation of neuron apoptotic process | 6.3584 | 6 | yes |
| GO:0019216 | regulation of lipid metabolic process | 5.7803 | 5 | yes |
| GO:0043524 | negative regulation of neuron apoptotic process | 4.6243 | 7 | yes |
| GO:0045834 | positive regulation of lipid metabolic process | 4.6243 | 5 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 4.0462 | 6 | yes |
| GO:0043550 | regulation of lipid kinase activity | 3.4682 | 6 | yes |
| GO:0043551 | regulation of phosphatidylinositol 3-kinase activity | 3.4682 | 7 | yes |
| GO:0090218 | positive regulation of lipid kinase activity | 2.8902 | 6 | yes |
| GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 2.8902 | 7 | yes |
| GO:0016197 | endosomal transport | 2.3121 | 4 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in AGAP2_HUMAN |
|---|---|---|---|---|
| DOID:0060038 | specific developmental disorder | 1.7341 | 3 | no |
| DOID:1059 | intellectual disability | 1.7341 | 4 | no |
| DOID:1289 | neurodegenerative disease | 1.7341 | 4 | no |
| DOID:331 | central nervous system disease | 1.7341 | 3 | no |
| DOID:0060307 | autosomal dominant intellectual developmental disorder | 1.1561 | 5 | no |
| DOID:0050753 | cerebellar ataxia | 1.1561 | 6 | no |
| DOID:0050950 | autosomal recessive cerebellar ataxia | 1.1561 | 7 | no |
| DOID:0050951 | hereditary ataxia | 1.1561 | 5 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| UNC5B_HUMAN | [view interactions] | Low throughput | no | yes |
| INSR_HUMAN | [view interactions] | Low throughput | no | yes |
| DCC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HOME1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| STA5A_HUMAN | [view interactions] | Low throughput | no | no |
| HOME2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| E41L1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RHOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| P85A_HUMAN | [view interactions] | Low throughput | no | yes |
| PRLR_HUMAN | [view interactions] | Low throughput | no | no |
| AKT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CDK4_HUMAN | [view interactions] | Low throughput | no | no |
| 1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MERL_HUMAN | [view interactions] | Low throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | Low throughput | no | no |
| ARF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIAH1_HUMAN | [view interactions] | High throughput | no | yes |
| K1C17_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYOME_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPGF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WASF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT5_HUMAN | [view interactions] | High throughput | no | no |
| RASL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRC7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQEC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IQEC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA2_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NMDE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNAI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DC1I1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DC1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PITM1_HUMAN | [view interactions] | High throughput | no | yes |
| LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
| PHF3_HUMAN | [view interactions] | High throughput | no | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EVI5L_HUMAN | [view interactions] | High throughput | no | yes |
| PCDH7_HUMAN | [view interactions] | High throughput | no | no |
| AHNK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TENR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GNA11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUMBL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AT1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM8_HUMAN | [view interactions] | High throughput | no | yes |
| KAD5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHAR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI5L1_HUMAN | [view interactions] | High throughput | no | no |
| SIK3_HUMAN | [view interactions] | High throughput | no | yes |
| KKCC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOGA1_HUMAN | [view interactions] | High throughput | no | yes |
| LIPA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIMS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| C170B_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
| 2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATD3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RPGF4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAB2P_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| KCD16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PQBP1_HUMAN | [view interactions] | High throughput | no | yes |
| SACS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRM5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCLO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCLK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKP1_HUMAN | [view interactions] | High throughput | no | no |
| MAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAG1_HUMAN | [view interactions] | High throughput | no | yes |
| GEPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKN2_HUMAN | [view interactions] | High throughput | no | yes |
| MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENAH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPTN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CACB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| LNX2_HUMAN | [view interactions] | High throughput | no | yes |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| A0A590UK10_HUMAN | [view interactions] | High throughput | no | no |
| ARHGI_HUMAN | [view interactions] | High throughput | no | no |
| DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCAM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NLGN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLGN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRCAM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CRCM_HUMAN | [view interactions] | High throughput | no | no |