ACTN1_HUMAN
Evidence for PS localization
Functions
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 32 | Gln | Lys | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
| 46 | Arg | Gln | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
| 105 | Val | Ile | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
| 225 | Glu | Lys | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
| 738 | Arg | Trp | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
| 752 | Arg | Gln | Bleedingdisorder,platelet-type,15(BDPLT15) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ACTN1_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 31.0078 | 4 | no |
| GO:0019901 | protein kinase binding | 28.6822 | 5 | no |
| GO:0046872 | metal ion binding | 27.9070 | 4 | yes |
| GO:0003779 | actin binding | 27.1318 | 4 | yes |
| GO:0045296 | cadherin binding | 23.2558 | 4 | no |
| GO:0017076 | purine nucleotide binding | 21.7054 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 21.7054 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 21.7054 | 4 | no |
| GO:0003723 | RNA binding | 20.9302 | 4 | yes |
| GO:0042803 | protein homodimerization activity | 15.5039 | 4 | yes |
| GO:0005509 | calcium ion binding | 11.6279 | 5 | yes |
| GO:0017166 | vinculin binding | 3.8760 | 4 | yes |
| GO:0030374 | nuclear receptor coactivator activity | 3.8760 | 4 | yes |
| GO:0003725 | double-stranded RNA binding | 3.1008 | 5 | yes |
| GO:0005519 | cytoskeletal regulatory protein binding | 1.5504 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ACTN1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 62.7907 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 60.4651 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 56.5891 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 55.8140 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 53.4884 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.7132 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 51.9380 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 49.6124 | 4 | no |
| GO:0009966 | regulation of signal transduction | 48.0620 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 45.7364 | 4 | no |
| GO:0006996 | organelle organization | 44.9612 | 4 | yes |
| GO:0010468 | regulation of gene expression | 41.8605 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 41.8605 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 40.3101 | 5 | no |
| GO:0022607 | cellular component assembly | 37.9845 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 37.2093 | 5 | no |
| GO:0009889 | regulation of biosynthetic process | 36.4341 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 36.4341 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 36.4341 | 5 | no |
| GO:0051049 | regulation of transport | 36.4341 | 4 | no |
| GO:0010941 | regulation of cell death | 34.8837 | 4 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 34.8837 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 34.1085 | 6 | no |
| GO:0031399 | regulation of protein modification process | 34.1085 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 34.1085 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 34.1085 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 33.3333 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 32.5581 | 6 | yes |
| GO:0043067 | regulation of programmed cell death | 32.5581 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.5581 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.5581 | 5 | no |
| GO:0007010 | cytoskeleton organization | 31.7829 | 5 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 31.7829 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.7829 | 5 | no |
| GO:0008104 | protein localization | 31.7829 | 4 | no |
| GO:0023056 | positive regulation of signaling | 31.7829 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 31.0078 | 7 | no |
| GO:0044087 | regulation of cellular component biogenesis | 31.0078 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 31.0078 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 30.2326 | 7 | no |
| GO:0051247 | positive regulation of protein metabolic process | 30.2326 | 6 | no |
| GO:0030030 | cell projection organization | 29.4574 | 4 | no |
| GO:0033043 | regulation of organelle organization | 29.4574 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 29.4574 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 28.6822 | 5 | no |
| GO:0071310 | cellular response to organic substance | 28.6822 | 4 | no |
| GO:0009894 | regulation of catabolic process | 27.9070 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 27.9070 | 5 | no |
| GO:0023057 | negative regulation of signaling | 27.9070 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 27.9070 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.5814 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 25.5814 | 5 | no |
| GO:0043085 | positive regulation of catalytic activity | 25.5814 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 24.8062 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.8062 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 24.8062 | 6 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 24.0310 | 4 | no |
| GO:0051338 | regulation of transferase activity | 24.0310 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.0310 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 24.0310 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 24.0310 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 23.2558 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.2558 | 6 | no |
| GO:0032880 | regulation of protein localization | 23.2558 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 23.2558 | 6 | no |
| GO:0031401 | positive regulation of protein modification process | 23.2558 | 7 | no |
| GO:0060548 | negative regulation of cell death | 23.2558 | 5 | no |
| GO:0010243 | response to organonitrogen compound | 23.2558 | 4 | no |
| GO:2000145 | regulation of cell motility | 23.2558 | 4 | no |
| GO:0036211 | protein modification process | 22.4806 | 4 | no |
| GO:0043412 | macromolecule modification | 22.4806 | 4 | no |
| GO:0051050 | positive regulation of transport | 22.4806 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 22.4806 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 22.4806 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 22.4806 | 7 | no |
| GO:0034330 | cell junction organization | 21.7054 | 4 | yes |
| GO:0051094 | positive regulation of developmental process | 21.7054 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.7054 | 5 | no |
| GO:0071702 | organic substance transport | 21.7054 | 4 | no |
| GO:0030334 | regulation of cell migration | 21.7054 | 5 | no |
| GO:0042127 | regulation of cell population proliferation | 21.7054 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 20.9302 | 5 | no |
| GO:0043549 | regulation of kinase activity | 20.9302 | 5 | no |
| GO:0045859 | regulation of protein kinase activity | 20.9302 | 6 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 20.9302 | 6 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 20.9302 | 8 | no |
| GO:0042327 | positive regulation of phosphorylation | 20.9302 | 8 | no |
| GO:1901701 | cellular response to oxygen-containing compound | 20.9302 | 4 | no |
| GO:0030155 | regulation of cell adhesion | 20.9302 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 20.1550 | 5 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 20.1550 | 5 | no |
| GO:0071705 | nitrogen compound transport | 20.1550 | 4 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.1550 | 6 | no |
| GO:0043066 | negative regulation of apoptotic process | 20.1550 | 7 | no |
| GO:0043069 | negative regulation of programmed cell death | 20.1550 | 6 | no |
| GO:0034329 | cell junction assembly | 16.2791 | 5 | yes |
| GO:0097435 | supramolecular fiber organization | 15.5039 | 4 | yes |
| GO:0007015 | actin filament organization | 13.9535 | 5 | yes |
| GO:0000904 | cell morphogenesis involved in differentiation | 7.7519 | 4 | yes |
| GO:0007044 | cell-substrate junction assembly | 5.4264 | 6 | yes |
| GO:0051017 | actin filament bundle assembly | 5.4264 | 5 | yes |
| GO:0061572 | actin filament bundle organization | 5.4264 | 6 | yes |
| GO:0150115 | cell-substrate junction organization | 5.4264 | 5 | yes |
| GO:0030099 | myeloid cell differentiation | 3.8760 | 4 | yes |
| GO:0048041 | focal adhesion assembly | 3.8760 | 7 | yes |
| GO:0055001 | muscle cell development | 3.8760 | 4 | yes |
| GO:0036344 | platelet morphogenesis | 1.5504 | 5 | yes |
| GO:0051639 | actin filament network formation | 1.5504 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ACTN1_HUMAN |
|---|---|---|---|---|
| DOID:1247 | blood coagulation disease | 2.3256 | 3 | yes |
| DOID:2218 | blood platelet disease | 2.3256 | 4 | yes |
| DOID:0080000 | muscular disease | 2.3256 | 3 | no |
| DOID:423 | myopathy | 2.3256 | 5 | no |
| DOID:66 | muscle tissue disease | 2.3256 | 4 | no |
| DOID:0111053 | platelet-type bleeding disorder 15 | 1.5504 | 5 | yes |
| DOID:3191 | nemaline myopathy | 1.5504 | 7 | no |
| DOID:422 | congenital structural myopathy | 1.5504 | 6 | no |
| DOID:0050700 | cardiomyopathy | 1.5504 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 1.5504 | 5 | no |
| DOID:114 | heart disease | 1.5504 | 3 | no |
| DOID:12930 | dilated cardiomyopathy | 1.5504 | 6 | no |
| DOID:1289 | neurodegenerative disease | 1.5504 | 4 | no |
| DOID:331 | central nervous system disease | 1.5504 | 3 | no |
| DOID:574 | peripheral nervous system disease | 1.5504 | 3 | no |
| DOID:870 | neuropathy | 1.5504 | 4 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CD5R2_HUMAN | [view interactions] | Low throughput | no | no |
| PYGB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| KCC2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDLI2_HUMAN | [view interactions] | Low throughput | no | no |
| GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MTAP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CSRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | Low throughput | no | no |
| ACTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ADIP_HUMAN | [view interactions] | Low throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GLCNE_HUMAN | [view interactions] | Low throughput | no | yes |
| CAC1C_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ASIC1_HUMAN | [view interactions] | Low throughput | no | no |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PLEK_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ST2B1_HUMAN | [view interactions] | Low throughput | no | yes |
| TITIN_HUMAN | [view interactions] | Low throughput | no | no |
| KCNA5_HUMAN | [view interactions] | Low throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HOME3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
| CTNA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| COHA1_HUMAN | [view interactions] | Low throughput | no | no |
| PDLI1_HUMAN | [view interactions] | Low throughput | no | yes |
| CD5R1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DEND_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| AA2AR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| M3K1_HUMAN | [view interactions] | Low throughput | no | yes |
| CLUS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MYOTI_HUMAN | [view interactions] | Low throughput | no | no |
| TRI59_HUMAN | [view interactions] | Low throughput | no | no |
| GRM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PHB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PKN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TBA1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DAG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| PALLD_HUMAN | [view interactions] | Low throughput | no | yes |
| ACHA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SPTN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDLI5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VASP_HUMAN | [view interactions] | Low throughput | no | yes |
| LDB3_HUMAN | [view interactions] | Low throughput | no | no |
| NMDZ1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ICAM5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RO52_HUMAN | [view interactions] | High throughput | no | yes |
| CIC_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| MT21E_HUMAN | [view interactions] | High throughput | no | no |
| INSI1_HUMAN | [view interactions] | High throughput | no | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| UBR5_HUMAN | [view interactions] | High throughput | no | no |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| CATB_HUMAN | [view interactions] | High throughput | no | yes |
| CATS_HUMAN | [view interactions] | High throughput | no | no |
| DPP4_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SIK2_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| RND3_HUMAN | [view interactions] | High throughput | no | no |
| CAAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TF65_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
| SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ATX2_HUMAN | [view interactions] | High throughput | no | yes |
| COIL_HUMAN | [view interactions] | High throughput | no | yes |
| SHPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FRDA_HUMAN | [view interactions] | High throughput | no | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GFI1B_HUMAN | [view interactions] | High throughput | no | no |
| LYRIC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX7_HUMAN | [view interactions] | High throughput | no | no |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAC1A_HUMAN | [view interactions] | High throughput | no | no |
| FAF2_HUMAN | [view interactions] | High throughput | no | yes |
| GIT2_HUMAN | [view interactions] | High throughput | no | yes |
| CDAN1_HUMAN | [view interactions] | High throughput | no | yes |
| NUMBL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF8_HUMAN | [view interactions] | High throughput | no | yes |
| TF2H1_HUMAN | [view interactions] | High throughput | no | yes |
| SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
| IMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PIAS4_HUMAN | [view interactions] | High throughput | no | yes |
| STAM2_HUMAN | [view interactions] | High throughput | no | yes |
| PSA1_HUMAN | [view interactions] | High throughput | no | yes |
| MYH15_HUMAN | [view interactions] | High throughput | no | yes |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYH2_HUMAN | [view interactions] | High throughput | no | yes |
| ODPX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANKR1_HUMAN | [view interactions] | High throughput | no | no |
| CY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTR1B_HUMAN | [view interactions] | High throughput | no | yes |
| ECSIT_HUMAN | [view interactions] | High throughput | no | yes |
| MTR1A_HUMAN | [view interactions] | High throughput | no | no |
| KDM5C_HUMAN | [view interactions] | High throughput | no | no |
| ALMS1_HUMAN | [view interactions] | High throughput | no | no |
| TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLUT4_HUMAN | [view interactions] | High throughput | no | no |
| CYB5B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATF2_HUMAN | [view interactions] | High throughput | no | yes |
| TOM40_HUMAN | [view interactions] | High throughput | no | yes |
| HSF5_HUMAN | [view interactions] | High throughput | no | no |
| SYJ2B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TLN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RCAS1_HUMAN | [view interactions] | High throughput | no | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TMPS2_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CATL1_HUMAN | [view interactions] | High throughput | no | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FURIN_HUMAN | [view interactions] | High throughput | no | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| AAKB1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLC4D_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| CLC4E_HUMAN | [view interactions] | High throughput | no | no |
| PER2_HUMAN | [view interactions] | High throughput | no | yes |
| ARX_HUMAN | [view interactions] | High throughput | no | no |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| COX15_HUMAN | [view interactions] | High throughput | no | yes |
| DLDH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNM1L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARK7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAG1_HUMAN | [view interactions] | High throughput | no | yes |
| BTK_HUMAN | [view interactions] | High throughput | no | no |
| SUN2_HUMAN | [view interactions] | High throughput | no | yes |
| DUX4_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIPT3_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| HSPB2_HUMAN | [view interactions] | High throughput | no | yes |
| AAPK1_HUMAN | [view interactions] | High throughput | no | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAV3_HUMAN | [view interactions] | High throughput | no | no |
| RD3_HUMAN | [view interactions] | High throughput | no | no |
| LITD1_HUMAN | [view interactions] | High throughput | no | no |
| WFDC2_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| OAS1_HUMAN | [view interactions] | High throughput | no | yes |
| CBY2_HUMAN | [view interactions] | High throughput | no | no |
| KCTD6_HUMAN | [view interactions] | High throughput | no | yes |
| MYOZ2_HUMAN | [view interactions] | High throughput | no | no |
| EPMIP_HUMAN | [view interactions] | High throughput | no | no |
| MILK2_HUMAN | [view interactions] | High throughput | no | no |
| PDLI4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CN119_HUMAN | [view interactions] | High throughput | no | yes |
| LNX1_HUMAN | [view interactions] | High throughput | no | yes |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| MYOZ1_HUMAN | [view interactions] | High throughput | no | no |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| NKAP1_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| APBP2_HUMAN | [view interactions] | High throughput | no | yes |
| IF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GA45G_HUMAN | [view interactions] | High throughput | no | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XRCC4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGAB_HUMAN | [view interactions] | High throughput | no | no |
| APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NHRF2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| B9D1_HUMAN | [view interactions] | High throughput | no | yes |
| TIFAB_HUMAN | [view interactions] | High throughput | no | no |
| STXB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KAT2B_HUMAN | [view interactions] | High throughput | no | yes |
| MED14_HUMAN | [view interactions] | High throughput | no | no |
| NR1H3_HUMAN | [view interactions] | High throughput | no | yes |
| DDIAS_HUMAN | [view interactions] | High throughput | no | no |
| SYP2L_HUMAN | [view interactions] | High throughput | no | no |
| CEBPA_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF6_HUMAN | [view interactions] | High throughput | no | yes |
| VATA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTPRQ_HUMAN | [view interactions] | High throughput | no | no |
| PCP2_HUMAN | [view interactions] | High throughput | no | no |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| ISG15_HUMAN | [view interactions] | High throughput | no | no |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| CBL_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
| IQCB1_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SVIL_HUMAN | [view interactions] | High throughput | no | yes |
| IGSF8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CD81_HUMAN | [view interactions] | High throughput | no | no |
| ICAM1_HUMAN | [view interactions] | High throughput | no | no |
| HACE1_HUMAN | [view interactions] | High throughput | no | no |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| EZH2_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| LUZP4_HUMAN | [view interactions] | High throughput | no | no |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| MCM5_HUMAN | [view interactions] | High throughput | no | no |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| FAF1_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE3C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| APEX1_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| TFCP2_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| LCK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CTNA3_HUMAN | [view interactions] | Computational | no | no |
| ITA1_HUMAN | [view interactions] | Computational | no | yes |
| PAXI_HUMAN | [view interactions] | Computational | no | yes |
| TENS1_HUMAN | [view interactions] | Computational | no | no |
| CSK_HUMAN | [view interactions] | Computational | no | yes |
| MAGI1_HUMAN | [view interactions] | Computational | no | no |
| PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| NOLC1_HUMAN | [view interactions] | Computational | no | yes |
| CTNA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CAN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| PARVB_HUMAN | [view interactions] | Computational | no | no |
| P85A_HUMAN | [view interactions] | Computational | no | yes |
| ACTS_HUMAN | [view interactions] | Computational | no | no |
| ILK_HUMAN | [view interactions] | Computational | no | no |
| ITA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CTND1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| CRKL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| ACTG_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| ITB3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SDC4_HUMAN | [view interactions] | Computational | no | yes |
| YES_HUMAN | [view entry] [view interactions] | Computational | yes | yes |