KIF1B_HUMAN
Isoform 1 mediates the transport of synaptic vesicles in neuronal cells. [View more on UniProt]
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To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
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Position | Amino acid | Mutation | Disease | Overlap with binding region |
---|---|---|---|---|
98 | Gln | Leu | Charcot-Marie-Toothdisease,axonal,2A1(CMT2A1) | - |
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in KIF1B_HUMAN |
---|---|---|---|---|
GO:0003723 | RNA binding | 32.7869 | 4 | no |
GO:0043168 | anion binding | 27.8689 | 4 | yes |
GO:0019900 | kinase binding | 27.8689 | 4 | no |
GO:0000166 | nucleotide binding | 26.2295 | 4 | yes |
GO:0017076 | purine nucleotide binding | 26.2295 | 5 | yes |
GO:0032555 | purine ribonucleotide binding | 26.2295 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 26.2295 | 4 | yes |
GO:0045296 | cadherin binding | 26.2295 | 4 | no |
GO:0019901 | protein kinase binding | 22.9508 | 5 | no |
GO:0005524 | ATP binding | 19.6721 | 5 | yes |
GO:0030554 | adenyl nucleotide binding | 19.6721 | 6 | yes |
GO:0032559 | adenyl ribonucleotide binding | 19.6721 | 5 | yes |
GO:0015631 | tubulin binding | 18.0328 | 4 | yes |
GO:0008017 | microtubule binding | 14.7541 | 5 | yes |
GO:0016462 | pyrophosphatase activity | 13.1148 | 5 | yes |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 13.1148 | 4 | yes |
GO:0017111 | ribonucleoside triphosphate phosphatase activity | 13.1148 | 6 | yes |
GO:0016887 | ATP hydrolysis activity | 9.8361 | 7 | yes |
GO:0019894 | kinesin binding | 4.9180 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in KIF1B_HUMAN |
---|---|---|---|---|
GO:0048523 | negative regulation of cellular process | 63.9344 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 60.6557 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 59.0164 | 4 | no |
GO:0048522 | positive regulation of cellular process | 55.7377 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 55.7377 | 4 | no |
GO:0008104 | protein localization | 47.5410 | 4 | no |
GO:0051128 | regulation of cellular component organization | 45.9016 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 42.6230 | 4 | no |
GO:0010468 | regulation of gene expression | 40.9836 | 6 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 40.9836 | 5 | no |
GO:0010646 | regulation of cell communication | 40.9836 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 40.9836 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 40.9836 | 5 | no |
GO:0009892 | negative regulation of metabolic process | 39.3443 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 39.3443 | 5 | no |
GO:0006996 | organelle organization | 39.3443 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 37.7049 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 36.0656 | 5 | no |
GO:0031324 | negative regulation of cellular metabolic process | 36.0656 | 5 | no |
GO:0051049 | regulation of transport | 36.0656 | 4 | no |
GO:0009966 | regulation of signal transduction | 34.4262 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 34.4262 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 34.4262 | 5 | no |
GO:0022607 | cellular component assembly | 34.4262 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 34.4262 | 5 | no |
GO:0006355 | regulation of DNA-templated transcription | 29.5082 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 29.5082 | 6 | no |
GO:0071702 | organic substance transport | 29.5082 | 4 | no |
GO:0071705 | nitrogen compound transport | 29.5082 | 4 | no |
GO:0051726 | regulation of cell cycle | 27.8689 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 27.8689 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 27.8689 | 5 | no |
GO:0009891 | positive regulation of biosynthetic process | 27.8689 | 5 | no |
GO:0009890 | negative regulation of biosynthetic process | 26.2295 | 5 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.2295 | 6 | no |
GO:0031327 | negative regulation of cellular biosynthetic process | 26.2295 | 6 | no |
GO:0031399 | regulation of protein modification process | 26.2295 | 6 | no |
GO:0007010 | cytoskeleton organization | 26.2295 | 5 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 26.2295 | 6 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 26.2295 | 6 | no |
GO:1902531 | regulation of intracellular signal transduction | 24.5902 | 5 | no |
GO:0015031 | protein transport | 24.5902 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 22.9508 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 22.9508 | 6 | no |
GO:0051248 | negative regulation of protein metabolic process | 22.9508 | 6 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.9508 | 4 | no |
GO:0006357 | regulation of transcription by RNA polymerase II | 22.9508 | 8 | no |
GO:0010648 | negative regulation of cell communication | 21.3115 | 5 | no |
GO:0023057 | negative regulation of signaling | 21.3115 | 4 | no |
GO:0034762 | regulation of transmembrane transport | 21.3115 | 4 | no |
GO:0042325 | regulation of phosphorylation | 21.3115 | 7 | no |
GO:0051050 | positive regulation of transport | 21.3115 | 4 | no |
GO:0051338 | regulation of transferase activity | 21.3115 | 4 | no |
GO:0033043 | regulation of organelle organization | 21.3115 | 5 | no |
GO:0030705 | cytoskeleton-dependent intracellular transport | 11.4754 | 4 | yes |
GO:0007268 | chemical synaptic transmission | 9.8361 | 7 | yes |
GO:0098916 | anterograde trans-synaptic signaling | 9.8361 | 6 | yes |
GO:0099536 | synaptic signaling | 9.8361 | 4 | yes |
GO:0099537 | trans-synaptic signaling | 9.8361 | 5 | yes |
GO:0006915 | apoptotic process | 8.1967 | 4 | yes |
GO:0008088 | axo-dendritic transport | 8.1967 | 5 | yes |
GO:0010970 | transport along microtubule | 8.1967 | 4 | yes |
GO:0099111 | microtubule-based transport | 8.1967 | 4 | yes |
GO:0098930 | axonal transport | 4.9180 | 6 | yes |
GO:0008089 | anterograde axonal transport | 3.2787 | 7 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STA13_HUMAN | [view interactions] | Low throughput | no | yes |
GIPC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CHP1_HUMAN | [view interactions] | Low throughput | no | yes |
CLAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CPEB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
DYSF_HUMAN | [view interactions] | Low throughput | no | no |
PARK7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CALX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
JKIP1_HUMAN | [view interactions] | Low throughput | no | no |
GABR1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
A4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VP33B_HUMAN | [view interactions] | High throughput | no | yes |
SPE39_HUMAN | [view interactions] | High throughput | no | yes |
GOPC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
DEFM_HUMAN | [view interactions] | High throughput | no | yes |
PP4R1_HUMAN | [view interactions] | High throughput | no | yes |
CAV3_HUMAN | [view interactions] | High throughput | no | no |
TULP2_HUMAN | [view interactions] | High throughput | no | no |
IF4A1_HUMAN | [view interactions] | High throughput | no | no |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN217_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIGI_HUMAN | [view interactions] | High throughput | no | yes |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
PNMA2_HUMAN | [view interactions] | High throughput | no | yes |
SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
FBLN5_HUMAN | [view interactions] | High throughput | no | no |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PURG_HUMAN | [view interactions] | High throughput | no | yes |
APBA1_HUMAN | [view interactions] | High throughput | no | no |
FRIL_HUMAN | [view interactions] | High throughput | no | yes |
LPXN_HUMAN | [view interactions] | High throughput | no | yes |
CCDC6_HUMAN | [view interactions] | High throughput | no | yes |
CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACVL1_HUMAN | [view interactions] | High throughput | no | yes |
BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
ARK2N_HUMAN | [view interactions] | High throughput | no | yes |
SC24A_HUMAN | [view interactions] | High throughput | no | no |
PSA7_HUMAN | [view interactions] | High throughput | no | yes |
ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI16_HUMAN | [view interactions] | High throughput | no | no |
CPNS1_HUMAN | [view interactions] | High throughput | no | yes |
ACTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HMGB2_HUMAN | [view interactions] | High throughput | no | yes |
PSA6_HUMAN | [view interactions] | High throughput | no | yes |
SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PI42C_HUMAN | [view interactions] | High throughput | no | yes |
TBCD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HOOK1_HUMAN | [view interactions] | High throughput | no | no |
HOOK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
BYST_HUMAN | [view interactions] | High throughput | no | yes |
CE350_HUMAN | [view interactions] | High throughput | no | yes |
CTIF_HUMAN | [view interactions] | High throughput | no | yes |
F120A_HUMAN | [view interactions] | High throughput | no | yes |
IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
IPO8_HUMAN | [view interactions] | High throughput | no | no |
PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TDRD3_HUMAN | [view interactions] | High throughput | no | yes |
TDRD7_HUMAN | [view interactions] | High throughput | no | yes |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
AKTIP_HUMAN | [view interactions] | High throughput | no | yes |
CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCDC9_HUMAN | [view interactions] | High throughput | no | yes |
HERC1_HUMAN | [view interactions] | High throughput | no | no |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FUBP3_HUMAN | [view interactions] | High throughput | no | yes |
FHI1A_HUMAN | [view interactions] | High throughput | no | yes |
MI4GD_HUMAN | [view interactions] | High throughput | no | yes |
F120C_HUMAN | [view interactions] | High throughput | no | yes |
GTPB1_HUMAN | [view interactions] | High throughput | no | yes |
MAGI1_HUMAN | [view interactions] | High throughput | no | no |
MEX3B_HUMAN | [view interactions] | High throughput | no | no |
TEX9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
PEX14_HUMAN | [view interactions] | High throughput | no | yes |
RPB3_HUMAN | [view interactions] | High throughput | no | yes |
PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB4A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
TRI36_HUMAN | [view interactions] | High throughput | no | no |
TBA4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARL10_HUMAN | [view interactions] | High throughput | no | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLK1_HUMAN | [view interactions] | High throughput | no | yes |
RAD50_HUMAN | [view interactions] | High throughput | no | yes |
FANCG_HUMAN | [view interactions] | High throughput | no | yes |
RBM7_HUMAN | [view interactions] | High throughput | no | yes |
ZSC26_HUMAN | [view interactions] | High throughput | no | no |
UBC9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTPRE_HUMAN | [view interactions] | High throughput | no | no |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
SIAH1_HUMAN | [view interactions] | High throughput | no | yes |
EF1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLIP4_HUMAN | [view interactions] | High throughput | no | yes |
LTOR5_HUMAN | [view interactions] | High throughput | no | yes |
PGM1_HUMAN | [view interactions] | High throughput | no | no |
POMP_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKNX1_HUMAN | [view interactions] | High throughput | no | yes |
RSPH1_HUMAN | [view interactions] | High throughput | no | no |
DSCR4_HUMAN | [view interactions] | High throughput | no | no |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
TRI55_HUMAN | [view interactions] | High throughput | no | no |
NINL_HUMAN | [view interactions] | High throughput | no | yes |
FHI2A_HUMAN | [view interactions] | High throughput | no | yes |
FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
KIF1C_HUMAN | [view interactions] | High throughput | no | yes |
MAST3_HUMAN | [view interactions] | High throughput | no | yes |
IF4E2_HUMAN | [view interactions] | High throughput | no | no |
SRGP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
SPD2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KSR1_HUMAN | [view interactions] | High throughput | no | yes |
CBY1_HUMAN | [view interactions] | High throughput | no | no |
RTKN_HUMAN | [view interactions] | High throughput | no | yes |
KI13B_HUMAN | [view interactions] | High throughput | no | yes |
LRFN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZBT21_HUMAN | [view interactions] | High throughput | no | yes |
DEN1A_HUMAN | [view interactions] | High throughput | no | no |
KCTD3_HUMAN | [view interactions] | High throughput | no | yes |
CING_HUMAN | [view interactions] | High throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECM29_HUMAN | [view interactions] | High throughput | no | no |
PK3C3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRAK2_HUMAN | [view interactions] | High throughput | no | yes |
PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MAGA1_HUMAN | [view interactions] | High throughput | no | no |
PAR6A_HUMAN | [view interactions] | High throughput | no | yes |
THOC2_HUMAN | [view interactions] | High throughput | no | yes |
SMC6_HUMAN | [view interactions] | High throughput | no | no |
NCOA4_HUMAN | [view interactions] | High throughput | no | no |
BACH1_HUMAN | [view interactions] | High throughput | no | no |
SMC1A_HUMAN | [view interactions] | High throughput | no | yes |
TMED2_HUMAN | [view interactions] | High throughput | no | yes |
MUS81_HUMAN | [view interactions] | High throughput | no | no |
YPEL5_HUMAN | [view interactions] | High throughput | no | yes |
NAV1_HUMAN | [view interactions] | High throughput | no | yes |
KIF1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BIN2_HUMAN | [view interactions] | High throughput | no | no |
CETN1_HUMAN | [view interactions] | High throughput | no | no |
KBP_HUMAN | [view interactions] | High throughput | no | yes |