Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RENT1_HUMAN

RNA-dependent helicase and ATPase required for nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. Recruited by release factors to stalled ribosomes together with the SMG1C protein kinase complex to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) (located 50-55 or more nucleotides downstream from the termination codon) through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Phosphorylated UPF1 is recognized by EST1B/SMG5, SMG6 and SMG7 which are thought to provide a link to the mRNA degradation machinery involving exonucleolytic and endonucleolytic pathways, and to serve as adapters to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation and allowing the recycling of NMD factors. UPF1 can also activate NMD without UPF2 or UPF3, and in the absence of the NMD-enhancing downstream EJC indicative for alternative NMD pathways. Plays a role in replication-dependent histone mRNA degradation at the end of phase S; the function is independent of UPF2. For the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed. The ATPase activity of UPF1 is required for disassembly of mRNPs undergoing NMD. Essential for embryonic viability. Together with UPF2 and dependent on TDRD6, mediates the degradation of mRNA hardoring long 3UTR by inducing the NMD machinery . [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in RENT1_HUMAN
GO:0003723 RNA binding 60.8247 4 yes
GO:0003729 mRNA binding 29.8969 5 no
GO:0017076 purine nucleotide binding 24.7423 4 yes
GO:0032555 purine ribonucleotide binding 23.7113 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 23.7113 4 yes
GO:0030554 adenyl nucleotide binding 18.5567 5 yes
GO:0005524 ATP binding 17.5258 5 yes
GO:0032559 adenyl ribonucleotide binding 17.5258 5 yes
GO:0046872 metal ion binding 17.5258 4 yes
GO:0003677 DNA binding 15.4639 4 yes
GO:0043565 sequence-specific DNA binding 6.1856 5 yes
GO:0008270 zinc ion binding 4.1237 6 yes
GO:0042162 telomeric DNA binding 4.1237 6 yes
GO:0046914 transition metal ion binding 4.1237 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in RENT1_HUMAN
GO:0060255 regulation of macromolecule metabolic process 69.0722 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 65.9794 4 yes
GO:0080090 regulation of primary metabolic process 65.9794 4 yes
GO:0031323 regulation of cellular metabolic process 65.9794 4 yes
GO:0048523 negative regulation of cellular process 65.9794 4 yes
GO:0010468 regulation of gene expression 62.8866 5 yes
GO:0048522 positive regulation of cellular process 62.8866 4 yes
GO:0009892 negative regulation of metabolic process 55.6701 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 53.6082 5 yes
GO:0009889 regulation of biosynthetic process 52.5773 4 yes
GO:0031326 regulation of cellular biosynthetic process 52.5773 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 51.5464 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 50.5155 5 yes
GO:0031324 negative regulation of cellular metabolic process 49.4845 5 yes
GO:0009893 positive regulation of metabolic process 47.4227 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 47.4227 5 yes
GO:0051246 regulation of protein metabolic process 46.3918 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 44.3299 5 yes
GO:0051252 regulation of RNA metabolic process 44.3299 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 44.3299 5 yes
GO:0010646 regulation of cell communication 40.2062 4 no
GO:0031325 positive regulation of cellular metabolic process 40.2062 5 yes
GO:0051128 regulation of cellular component organization 39.1753 4 yes
GO:0090304 nucleic acid metabolic process 37.1134 4 yes
GO:0016070 RNA metabolic process 35.0515 5 yes
GO:0051248 negative regulation of protein metabolic process 34.0206 6 yes
GO:0009966 regulation of signal transduction 34.0206 4 no
GO:0010629 negative regulation of gene expression 32.9897 6 yes
GO:0051247 positive regulation of protein metabolic process 30.9278 6 no
GO:0022607 cellular component assembly 30.9278 4 no
GO:0009890 negative regulation of biosynthetic process 30.9278 5 yes
GO:1903506 regulation of nucleic acid-templated transcription 29.8969 7 no
GO:2001141 regulation of RNA biosynthetic process 29.8969 6 no
GO:0010558 negative regulation of macromolecule biosynthetic process 29.8969 6 yes
GO:0031327 negative regulation of cellular biosynthetic process 29.8969 6 yes
GO:0006355 regulation of DNA-templated transcription 28.8660 6 no
GO:0006396 RNA processing 28.8660 6 no
GO:0010628 positive regulation of gene expression 28.8660 6 no
GO:0031399 regulation of protein modification process 27.8351 6 no
GO:0010608 post-transcriptional regulation of gene expression 26.8041 6 yes
GO:0048584 positive regulation of response to stimulus 25.7732 4 no
GO:0006996 organelle organization 24.7423 4 yes
GO:0009894 regulation of catabolic process 24.7423 4 yes
GO:2000112 regulation of cellular macromolecule biosynthetic process 23.7113 6 yes
GO:0051726 regulation of cell cycle 23.7113 4 no
GO:0010941 regulation of cell death 23.7113 4 no
GO:0009891 positive regulation of biosynthetic process 23.7113 5 no
GO:0031328 positive regulation of cellular biosynthetic process 23.7113 6 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 23.7113 6 no
GO:0010647 positive regulation of cell communication 23.7113 5 no
GO:0023056 positive regulation of signaling 23.7113 4 no
GO:0006417 regulation of translation 23.7113 6 yes
GO:0034248 regulation of cellular amide metabolic process 23.7113 5 yes
GO:0071702 organic substance transport 22.6804 4 yes
GO:1902531 regulation of intracellular signal transduction 22.6804 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 22.6804 6 no
GO:0042127 regulation of cell population proliferation 22.6804 4 no
GO:0016071 mRNA metabolic process 22.6804 6 yes
GO:0031329 regulation of cellular catabolic process 22.6804 5 yes
GO:0071705 nitrogen compound transport 21.6495 4 yes
GO:0043933 protein-containing complex organization 21.6495 4 no
GO:0044087 regulation of cellular component biogenesis 21.6495 4 no
GO:0051253 negative regulation of RNA metabolic process 21.6495 6 no
GO:0009967 positive regulation of signal transduction 21.6495 5 no
GO:0033043 regulation of organelle organization 21.6495 5 yes
GO:0001932 regulation of protein phosphorylation 20.6186 7 no
GO:0019220 regulation of phosphate metabolic process 20.6186 6 no
GO:0042325 regulation of phosphorylation 20.6186 7 no
GO:0043412 macromolecule modification 20.6186 4 no
GO:0051174 regulation of phosphorus metabolic process 20.6186 5 no
GO:0051130 positive regulation of cellular component organization 20.6186 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.6186 6 yes
GO:0071310 cellular response to organic substance 18.5567 4 yes
GO:1903311 regulation of mRNA metabolic process 17.5258 6 yes
GO:0009057 macromolecule catabolic process 16.4948 4 yes
GO:0051254 positive regulation of RNA metabolic process 15.4639 6 yes
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 15.4639 7 yes
GO:0017148 negative regulation of translation 15.4639 7 yes
GO:0034249 negative regulation of cellular amide metabolic process 15.4639 6 yes
GO:0044265 cellular macromolecule catabolic process 15.4639 4 yes
GO:0061013 regulation of mRNA catabolic process 10.3093 6 yes
GO:1901361 organic cyclic compound catabolic process 10.3093 4 yes
GO:1901701 cellular response to oxygen-containing compound 10.3093 4 yes
GO:0006401 RNA catabolic process 10.3093 5 yes
GO:0009896 positive regulation of catabolic process 10.3093 5 yes
GO:0019439 aromatic compound catabolic process 10.3093 4 yes
GO:0034655 nucleobase-containing compound catabolic process 10.3093 4 yes
GO:0044270 cellular nitrogen compound catabolic process 10.3093 4 yes
GO:0046700 heterocycle catabolic process 10.3093 4 yes
GO:0051028 mRNA transport 9.2784 5 yes
GO:0071396 cellular response to lipid 9.2784 5 yes
GO:0006402 mRNA catabolic process 9.2784 6 yes
GO:0015931 nucleobase-containing compound transport 9.2784 5 yes
GO:0033993 response to lipid 9.2784 4 yes
GO:0034097 response to cytokine 9.2784 4 yes
GO:0043488 regulation of mRNA stability 9.2784 4 yes
GO:0050657 nucleic acid transport 9.2784 6 yes
GO:0050658 RNA transport 9.2784 4 yes
GO:0051052 regulation of DNA metabolic process 8.2474 5 yes
GO:0071345 cellular response to cytokine stimulus 8.2474 5 yes
GO:0051169 nuclear transport 7.2165 4 yes
GO:0000956 nuclear-transcribed mRNA catabolic process 7.2165 7 yes
GO:0006913 nucleocytoplasmic transport 7.2165 5 yes
GO:0006974 cellular response to DNA damage stimulus 7.2165 4 yes
GO:0031331 positive regulation of cellular catabolic process 7.2165 6 yes
GO:0051168 nuclear export 6.1856 6 yes
GO:1903313 positive regulation of mRNA metabolic process 6.1856 7 yes
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 6.1856 8 yes
GO:0033044 regulation of chromosome organization 6.1856 6 yes
GO:0006259 DNA metabolic process 5.1546 4 yes
GO:0032204 regulation of telomere maintenance 5.1546 6 yes
GO:0006405 RNA export from nucleus 4.1237 5 yes
GO:0051276 chromosome organization 3.0928 5 yes
GO:0061014 positive regulation of mRNA catabolic process 3.0928 7 yes
GO:0070555 response to interleukin-1 3.0928 5 yes
GO:0071219 cellular response to molecule of bacterial origin 3.0928 4 yes
GO:0071222 cellular response to lipopolysaccharide 3.0928 5 yes
GO:0071347 cellular response to interleukin-1 3.0928 6 yes
GO:0002237 response to molecule of bacterial origin 3.0928 4 yes
GO:0006281 DNA repair 3.0928 5 yes
GO:0006406 mRNA export from nucleus 3.0928 6 yes
GO:0032496 response to lipopolysaccharide 3.0928 4 yes
GO:0040029 epigenetic regulation of gene expression 3.0928 6 yes
GO:0043244 regulation of protein-containing complex disassembly 3.0928 5 yes
GO:0061157 mRNA destabilization 2.0619 5 yes
GO:0061158 3-UTR-mediated mRNA destabilization 2.0619 6 yes
GO:0071044 histone mRNA catabolic process 2.0619 8 yes
GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay 2.0619 8 yes
GO:0000723 telomere maintenance 2.0619 5 yes
GO:0006260 DNA replication 2.0619 5 yes
GO:0006449 regulation of translational termination 2.0619 6 yes
GO:0007549 dosage compensation 2.0619 7 yes
GO:0008334 histone mRNA metabolic process 2.0619 7 yes
GO:0009048 dosage compensation by inactivation of X chromosome 2.0619 8 yes
GO:0032200 telomere organization 2.0619 6 yes
GO:0050779 RNA destabilization 2.0619 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in RENT1_HUMAN
DOID:1289 neurodegenerative disease 3.0928 4 no
DOID:331 central nervous system disease 3.0928 3 no
DOID:231 motor neuron disease 2.0619 5 no
DOID:332 amyotrophic lateral sclerosis 2.0619 6 no
DOID:37 skin disease 2.0619 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DDX6_HUMAN [view entry] [view interactions] Low throughput yes yes
FUS_HUMAN [view entry] [view interactions] Low throughput yes yes
XRN1_HUMAN [view interactions] Low throughput no yes
EXOS2_HUMAN [view interactions] Low throughput no yes
DPOD1_HUMAN [view interactions] Low throughput no yes
ATR_HUMAN [view interactions] Low throughput no no
SMG8_HUMAN [view interactions] Low throughput no yes
SMG9_HUMAN [view interactions] Low throughput no yes
RSMN_HUMAN [view interactions] Low throughput no yes
RSMB_HUMAN [view interactions] Low throughput no yes
EIF3A_HUMAN [view entry] [view interactions] Low throughput yes yes
EIF3B_HUMAN [view interactions] Low throughput no yes
IF2A_HUMAN [view entry] [view interactions] Low throughput yes yes
IF2B_HUMAN [view interactions] Low throughput no yes
PNRC1_HUMAN [view interactions] Low throughput no yes
PNRC2_HUMAN [view interactions] Low throughput no yes
RENT2_HUMAN [view interactions] Low throughput no no
REN3B_HUMAN [view interactions] Low throughput no yes
DCP1A_HUMAN [view interactions] Low throughput no yes
DCP2_HUMAN [view interactions] Low throughput no yes
MKRN3_HUMAN [view interactions] Low throughput no yes
REN3A_HUMAN [view interactions] Low throughput no yes
ERF1_HUMAN [view interactions] Low throughput no yes
ERF3A_HUMAN [view interactions] Low throughput no yes
RNPS1_HUMAN [view interactions] Low throughput no yes
ERF3B_HUMAN [view interactions] Low throughput no yes
SMG1_HUMAN [view interactions] Low throughput no yes
TERT_HUMAN [view interactions] Low throughput no no
ACD_HUMAN [view interactions] Low throughput no no
STAU1_HUMAN [view entry] [view interactions] Low throughput yes yes
LORF1_HUMAN [view interactions] Low throughput no no
SLBP_HUMAN [view interactions] Low throughput no yes
CASC3_HUMAN [view interactions] Low throughput no yes
ERI1_HUMAN [view interactions] Low throughput no yes
PABP1_HUMAN [view entry] [view interactions] Low throughput yes yes
DSRAD_HUMAN [view entry] [view interactions] Low throughput yes yes
INT6_HUMAN [view interactions] Low throughput no yes
IPSP_HUMAN [view interactions] High throughput no no
SRP09_HUMAN [view interactions] High throughput no no
BMI1_HUMAN [view interactions] High throughput no yes
MNS1_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
HNRPK_HUMAN [view entry] [view interactions] High throughput yes yes
MOV10_HUMAN [view interactions] High throughput no no
UFM1_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
ROA0_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
STRAP_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ZFR_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
SRS12_HUMAN [view interactions] High throughput no no
NBEL2_HUMAN [view interactions] High throughput no no
NSRP1_HUMAN [view interactions] High throughput no yes
KAD2_HUMAN [view interactions] High throughput no no
CNTRL_HUMAN [view interactions] High throughput no yes
ATX2_HUMAN [view interactions] High throughput no yes
NIN_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
SCLT1_HUMAN [view interactions] High throughput no yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
CE104_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
SMAG2_HUMAN [view interactions] High throughput no yes
STIL_HUMAN [view interactions] High throughput no no
MSI2H_HUMAN [view interactions] High throughput no yes
CE170_HUMAN [view interactions] High throughput no yes
ROAA_HUMAN [view interactions] High throughput no yes
CE162_HUMAN [view interactions] High throughput no yes
NRIP1_HUMAN [view interactions] High throughput no yes
FTM_HUMAN [view interactions] High throughput no yes
ROA3_HUMAN [view entry] [view interactions] High throughput yes yes
CEP19_HUMAN [view interactions] High throughput no no
HNRDL_HUMAN [view interactions] High throughput no yes
DYRK2_HUMAN [view interactions] High throughput no yes
HNRPR_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
IF2B3_HUMAN [view interactions] High throughput no no
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
ATG12_HUMAN [view interactions] High throughput no yes
SPRNG_HUMAN [view interactions] High throughput no yes
EXOS4_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
PARN_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
EXOSX_HUMAN [view interactions] High throughput no yes
OTUD4_HUMAN [view interactions] High throughput no yes
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
HDAC5_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
SIR7_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view interactions] High throughput no yes
TS101_HUMAN [view entry] [view interactions] High throughput yes yes
P5F1B_HUMAN [view interactions] High throughput no no
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
PO5F1_HUMAN [view interactions] High throughput no yes
VPS35_HUMAN [view entry] [view interactions] High throughput yes yes
CDK2_HUMAN [view interactions] High throughput no yes
TMX1_HUMAN [view interactions] High throughput no no
ABCF3_HUMAN [view entry] [view interactions] High throughput yes yes
DIAP1_HUMAN [view interactions] High throughput no yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
SMCA4_HUMAN [view interactions] High throughput no yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
TTC4_HUMAN [view interactions] High throughput no yes
MGN_HUMAN [view interactions] High throughput no yes
UBL7_HUMAN [view interactions] High throughput no yes
HBB_HUMAN [view interactions] High throughput no no
DDX5_HUMAN [view entry] [view interactions] High throughput yes yes
EST1A_HUMAN [view interactions] High throughput no yes
RFIP5_HUMAN [view entry] [view interactions] High throughput yes yes
MGN2_HUMAN [view interactions] High throughput no yes
TIAR_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
DAZP1_HUMAN [view interactions] High throughput no yes
SYYM_HUMAN [view interactions] High throughput no no
NGAL_HUMAN [view interactions] High throughput no no
FBW1B_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
AGR2_HUMAN [view interactions] High throughput no no
ITA4_HUMAN [view interactions] High throughput no no
KS6A2_HUMAN [view interactions] High throughput no yes
RUVB1_HUMAN [view interactions] High throughput no yes
ALG13_HUMAN [view interactions] High throughput no yes
RUVB2_HUMAN [view interactions] High throughput no yes
CELF1_HUMAN [view interactions] High throughput no yes
TADBP_HUMAN [view interactions] High throughput no yes
CNOT9_HUMAN [view interactions] High throughput no yes
LN28A_HUMAN [view interactions] High throughput no no
CPEB4_HUMAN [view entry] [view interactions] High throughput yes no
POP1_HUMAN [view interactions] High throughput no no
CSDE1_HUMAN [view interactions] High throughput no yes
STAU2_HUMAN [view interactions] High throughput no yes
DAZL_HUMAN [view interactions] High throughput no no
DNA2_HUMAN [view interactions] High throughput no yes
DDX3X_HUMAN [view entry] [view interactions] High throughput yes yes
NS1BP_HUMAN [view interactions] High throughput no yes
IF4A1_HUMAN [view interactions] High throughput no no
EZH2_HUMAN [view interactions] High throughput no no
IF4A2_HUMAN [view entry] [view interactions] High throughput yes yes
SUZ12_HUMAN [view interactions] High throughput no no
F120C_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
EED_HUMAN [view interactions] High throughput no yes
FUBP3_HUMAN [view interactions] High throughput no yes
H11_HUMAN [view interactions] High throughput no no
FXR2_HUMAN [view entry] [view interactions] High throughput yes yes
TRA2A_HUMAN [view interactions] High throughput no yes
GRSF1_HUMAN [view interactions] High throughput no yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
IF2B2_HUMAN [view interactions] High throughput no yes
MK67I_HUMAN [view interactions] High throughput no yes
KIF1B_HUMAN [view interactions] High throughput no yes
MEMO1_HUMAN [view interactions] High throughput no yes
LSM12_HUMAN [view interactions] High throughput no yes
ZC3H3_HUMAN [view interactions] High throughput no yes
LS14A_HUMAN [view interactions] High throughput no yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
MEX3B_HUMAN [view interactions] High throughput no no
PRR11_HUMAN [view interactions] High throughput no no
MKRN2_HUMAN [view interactions] High throughput no yes
ILF2_HUMAN [view interactions] High throughput no yes
NUFP2_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
PAIP2_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
PRC2A_HUMAN [view interactions] High throughput no yes
CNOT2_HUMAN [view interactions] High throughput no yes
PUM1_HUMAN [view interactions] High throughput no yes
OAZ1_HUMAN [view interactions] High throughput no yes
R3HD2_HUMAN [view interactions] High throughput no yes
SORT_HUMAN [view interactions] High throughput no yes
RBMS1_HUMAN [view interactions] High throughput no no
SAMD1_HUMAN [view interactions] High throughput no no
TDRD3_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
TRI56_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
UBP2L_HUMAN [view interactions] High throughput no yes
TAOK2_HUMAN [view entry] [view interactions] High throughput yes yes
UNK_HUMAN [view interactions] High throughput no yes
MKRN1_HUMAN [view interactions] High throughput no no
YTHD1_HUMAN [view interactions] High throughput no no
PCGF1_HUMAN [view interactions] High throughput no yes
YTHD2_HUMAN [view interactions] High throughput no yes
DPPA4_HUMAN [view interactions] High throughput no no
YTHD3_HUMAN [view interactions] High throughput no no
U2AF2_HUMAN [view interactions] High throughput no yes
Z3H7A_HUMAN [view interactions] High throughput no no
IFIX_HUMAN [view interactions] High throughput no no
TTP_HUMAN [view interactions] High throughput no yes
WDR46_HUMAN [view interactions] High throughput no yes
4ET_HUMAN [view interactions] High throughput no yes
ELAV2_HUMAN [view interactions] High throughput no yes
SMAP2_HUMAN [view interactions] High throughput no yes
NOP53_HUMAN [view interactions] High throughput no yes
TIA1_HUMAN [view interactions] High throughput no no
DGCR8_HUMAN [view entry] [view interactions] High throughput yes yes
TOP3B_HUMAN [view interactions] High throughput no no
CDX1_HUMAN [view interactions] High throughput no no
CTIF_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
MARF1_HUMAN [view interactions] High throughput no yes
H1T_HUMAN [view interactions] High throughput no no
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
PRDM5_HUMAN [view interactions] High throughput no yes
CH082_HUMAN [view interactions] High throughput no yes
ZCRB1_HUMAN [view interactions] High throughput no no
CHCH1_HUMAN [view interactions] High throughput no yes
STRBP_HUMAN [view interactions] High throughput no yes
DDX28_HUMAN [view interactions] High throughput no yes
H14_HUMAN [view interactions] High throughput no yes
EXD2_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
E4F1_HUMAN [view interactions] High throughput no yes
DNJA2_HUMAN [view entry] [view interactions] High throughput yes yes
H2AX_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
NXF2_HUMAN [view interactions] High throughput no no
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
ZCCHV_HUMAN [view interactions] High throughput no yes
RS20_HUMAN [view entry] [view interactions] High throughput yes yes
SSF1_HUMAN [view interactions] High throughput no yes
PAIRB_HUMAN [view interactions] High throughput no yes
RPF1_HUMAN [view interactions] High throughput no yes
STIM1_HUMAN [view interactions] High throughput no yes
NSA2_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
ZC3H1_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
FGF8_HUMAN [view interactions] High throughput no no
ZN576_HUMAN [view interactions] High throughput no no
RBM3_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
G3BP1_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
TRIP4_HUMAN [view interactions] High throughput no yes
BMP4_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
PPIE_HUMAN [view interactions] High throughput no yes
HBP1_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
ARI1_HUMAN [view interactions] High throughput no yes
SPDLY_HUMAN [view interactions] High throughput no yes
RIOK1_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
WWOX_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
CGAS_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
GRWD1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
TLR9_HUMAN [view interactions] High throughput no no
AMRA1_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
NR2C2_HUMAN [view interactions] High throughput no yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
ZDH18_HUMAN [view interactions] High throughput no yes
ZDH23_HUMAN [view interactions] High throughput no no
ATX1_HUMAN [view interactions] High throughput no yes
ZBT7B_HUMAN [view interactions] High throughput no no
BIRC3_HUMAN [view interactions] High throughput no no
LMBRL_HUMAN [view interactions] High throughput no no
NFX1_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
CMTR1_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
PLK1_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
UBR5_HUMAN [view interactions] High throughput no no
ANLN_HUMAN [view interactions] High throughput no yes
LSM8_HUMAN [view interactions] High throughput no yes
AURKB_HUMAN [view interactions] High throughput no yes
DXO_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
HIRA_HUMAN [view interactions] High throughput no yes
ECT2_HUMAN [view interactions] High throughput no no
TR112_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
PKHB2_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
NADE_HUMAN [view interactions] High throughput no yes
LRC59_HUMAN [view entry] [view interactions] High throughput yes yes
ACSA_HUMAN [view interactions] High throughput no no
INS_HUMAN [view interactions] High throughput no no
ABHGA_HUMAN [view entry] [view interactions] High throughput yes yes
BRD4_HUMAN [view interactions] High throughput no yes
RHXF2_HUMAN [view interactions] High throughput no no
NUPR1_HUMAN [view interactions] High throughput no no
RPRD2_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
GNPTG_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
LIN41_HUMAN [view interactions] High throughput no no
ATF3_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
GA45A_HUMAN [view interactions] High throughput no no
HXA5_HUMAN [view interactions] High throughput no no
MYB_HUMAN [view interactions] High throughput no yes
E2F7_HUMAN [view interactions] High throughput no no
EDC4_HUMAN [view interactions] High throughput no yes
UBP10_HUMAN [view interactions] High throughput no yes
EDC3_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
RENT1_HUMAN [view entry] [view interactions] High throughput yes yes
FZR1_HUMAN [view interactions] High throughput no no
AGO1_HUMAN [view interactions] High throughput no no
SPOP_HUMAN [view interactions] High throughput no no
AGO2_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
RBM8A_HUMAN [view interactions] High throughput no yes
NR4A1_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
SRRM1_HUMAN [view interactions] High throughput no yes
THAP3_HUMAN [view interactions] High throughput no yes
NXF1_HUMAN [view interactions] High throughput no yes
SRSF6_HUMAN [view interactions] High throughput no yes
THOC4_HUMAN [view interactions] High throughput no no
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
DEK_HUMAN [view interactions] High throughput no yes
LAR4B_HUMAN [view interactions] High throughput no yes
RN151_HUMAN [view interactions] High throughput no no
NUP42_HUMAN [view interactions] High throughput no no
ZN346_HUMAN [view interactions] High throughput no yes
HNRL2_HUMAN [view interactions] High throughput no yes
RED1_HUMAN [view interactions] High throughput no no
RC3H1_HUMAN [view interactions] High throughput no yes
RBM47_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
PAI2B_HUMAN [view interactions] High throughput no no
RL1D1_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
RBMS2_HUMAN [view interactions] High throughput no yes
AIM2_HUMAN [view interactions] High throughput no no
SURF6_HUMAN [view interactions] High throughput no yes
MNDA_HUMAN [view interactions] High throughput no no
F120A_HUMAN [view interactions] High throughput no yes
PRR3_HUMAN [view interactions] High throughput no no
MAP7_HUMAN [view interactions] High throughput no yes
URM1_HUMAN [view interactions] High throughput no yes
RL17_HUMAN [view entry] [view interactions] High throughput yes yes
ZBT47_HUMAN [view interactions] High throughput no yes
PABP2_HUMAN [view interactions] High throughput no yes
RL26_HUMAN [view entry] [view interactions] High throughput yes yes
PER1_HUMAN [view interactions] High throughput no no
IF4E_HUMAN [view entry] [view interactions] High throughput yes yes
ABT1_HUMAN [view interactions] High throughput no no
NCBP1_HUMAN [view interactions] High throughput no yes
RS30_HUMAN [view interactions] High throughput no yes
NAC1_HUMAN [view entry] [view interactions] High throughput yes yes
HNRC1_HUMAN [view interactions] High throughput no no
DICER_HUMAN [view entry] [view interactions] High throughput yes yes
PABP5_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
HNRPC_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
SRSF3_HUMAN [view interactions] High throughput no yes
KPCD1_HUMAN [view interactions] High throughput no yes
H2AB2_HUMAN [view interactions] High throughput no no
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
PURG_HUMAN [view interactions] High throughput no yes
NCBP3_HUMAN [view interactions] High throughput no yes
AT7L1_HUMAN [view interactions] High throughput no yes
NCBP2_HUMAN [view interactions] High throughput no yes
LN28B_HUMAN [view interactions] High throughput no no
IMP1L_HUMAN [view interactions] High throughput no yes
LYAR_HUMAN [view interactions] High throughput no no
IMP2L_HUMAN [view interactions] High throughput no yes
RBM4B_HUMAN [view interactions] High throughput no yes
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
RFOX2_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
PAIP1_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
MBB1A_HUMAN [view interactions] High throughput no yes
CBX6_HUMAN [view interactions] High throughput no yes
SMG7_HUMAN [view interactions] High throughput no no
SZRD1_HUMAN [view interactions] High throughput no yes
SMG5_HUMAN [view interactions] High throughput no no
PUF60_HUMAN [view interactions] High throughput no yes
KDM4A_HUMAN [view interactions] High throughput no yes
RU1C_HUMAN [view interactions] High throughput no yes
XPO1_HUMAN [view entry] [view interactions] High throughput yes yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
NEIL1_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
SRSF1_HUMAN [view interactions] High throughput no yes
FBRL_HUMAN [view interactions] High throughput no yes
SRSF7_HUMAN [view interactions] High throughput no yes
B2L14_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
OASL_HUMAN [view interactions] High throughput no no
EF1D_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
FBXW7_HUMAN [view interactions] High throughput no yes
CPEB1_HUMAN [view entry] [view interactions] High throughput yes no
HECD1_HUMAN [view interactions] High throughput no yes
KLF4_HUMAN [view interactions] High throughput no no
SIR6_HUMAN [view interactions] High throughput no yes
SOX15_HUMAN [view interactions] High throughput no no
RBCC1_HUMAN [view interactions] High throughput no no
NDRG1_HUMAN [view entry] [view interactions] High throughput yes yes
PEG10_HUMAN [view interactions] High throughput no no
TRFE_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
RHBT2_HUMAN [view interactions] High throughput no no
SNW1_HUMAN [view interactions] High throughput no yes
CAPR1_HUMAN [view entry] [view interactions] High throughput yes yes
CDC5L_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
CLCA_HUMAN [view entry] [view interactions] High throughput yes no
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
DDX21_HUMAN [view interactions] High throughput no yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
DHX9_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
G3BP2_HUMAN [view entry] [view interactions] High throughput yes yes
STING_HUMAN [view interactions] High throughput no yes
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
YBOX1_HUMAN [view interactions] High throughput no yes
HNRH1_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
HNRPL_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
IF2B1_HUMAN [view interactions] High throughput no no
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
ILF3_HUMAN [view interactions] High throughput no yes
HERC2_HUMAN [view interactions] High throughput no yes
MAP2_HUMAN [view interactions] High throughput no yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
PSPC1_HUMAN [view interactions] High throughput no yes
ASF1A_HUMAN [view interactions] High throughput no no
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC4_HUMAN [view interactions] High throughput no yes
RS16_HUMAN [view entry] [view interactions] High throughput yes yes
RS26_HUMAN [view entry] [view interactions] Computational yes yes
SKIV2_HUMAN [view entry] [view interactions] Computational yes yes
DHX34_HUMAN [view interactions] Computational no no
XRN2_HUMAN [view interactions] Computational no yes
RBMX_HUMAN [view entry] [view interactions] Computational yes yes
LSM1_HUMAN [view interactions] Computational no no
IF4G1_HUMAN [view entry] [view interactions] Computational yes yes
PYM1_HUMAN [view interactions] Computational no yes
PP2AA_HUMAN [view entry] [view interactions] Computational yes yes
HBS1L_HUMAN [view interactions] Computational no yes