DGCR8_HUMAN
Evidence for PS localization
Functions
Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs (PubMed, PubMed). The heme-bound DGCR8 dimer binds pri-miRNAs as a cooperative trimer (of dimers) and is active in triggering pri-miRNA cleavage, whereas the heme-free DGCR8 monomer binds pri-miRNAs as a dimer and is much less active. Both double-stranded and single-stranded regions of a pri-miRNA are required for its binding (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Specifically recognizes and binds N6-methyladenosine (m6A)-containing pri-miRNAs, a modification required for pri-miRNAs processing (PubMed). Involved in the silencing of embryonic stem cell self-renewal . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DGCR8_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 66.6667 | 4 | yes |
| GO:0000166 | nucleotide binding | 26.1905 | 4 | no |
| GO:0017076 | purine nucleotide binding | 26.1905 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 26.1905 | 6 | no |
| GO:0043168 | anion binding | 26.1905 | 4 | no |
| GO:0043169 | cation binding | 23.8095 | 4 | yes |
| GO:0046872 | metal ion binding | 23.8095 | 5 | yes |
| GO:0005524 | ATP binding | 23.8095 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 23.8095 | 4 | no |
| GO:0032559 | adenyl ribonucleotide binding | 23.8095 | 5 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.8095 | 4 | no |
| GO:0003677 | DNA binding | 21.4286 | 4 | no |
| GO:0003725 | double-stranded RNA binding | 14.2857 | 5 | yes |
| GO:0042803 | protein homodimerization activity | 11.9048 | 4 | yes |
| GO:0070878 | primary miRNA binding | 9.5238 | 5 | yes |
| GO:0020037 | heme binding | 4.7619 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DGCR8_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 57.1429 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 54.7619 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 54.7619 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 54.7619 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 54.7619 | 5 | yes |
| GO:0080090 | regulation of primary metabolic process | 54.7619 | 4 | yes |
| GO:0010468 | regulation of gene expression | 52.3810 | 6 | yes |
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | yes |
| GO:0090304 | nucleic acid metabolic process | 50.0000 | 4 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 47.6190 | 5 | yes |
| GO:0016070 | RNA metabolic process | 45.2381 | 5 | yes |
| GO:0051252 | regulation of RNA metabolic process | 45.2381 | 5 | yes |
| GO:0048523 | negative regulation of cellular process | 42.8571 | 4 | no |
| GO:0006396 | RNA processing | 38.0952 | 6 | yes |
| GO:0009893 | positive regulation of metabolic process | 35.7143 | 4 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 35.7143 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 33.3333 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 33.3333 | 5 | no |
| GO:0009059 | macromolecule biosynthetic process | 33.3333 | 4 | no |
| GO:0010646 | regulation of cell communication | 33.3333 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 30.9524 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 30.9524 | 6 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 30.9524 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 30.9524 | 6 | yes |
| GO:0022607 | cellular component assembly | 30.9524 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.5714 | 5 | no |
| GO:0051128 | regulation of cellular component organization | 28.5714 | 4 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 26.1905 | 5 | yes |
| GO:0006355 | regulation of DNA-templated transcription | 26.1905 | 7 | no |
| GO:0009890 | negative regulation of biosynthetic process | 26.1905 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 26.1905 | 6 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 26.1905 | 6 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 26.1905 | 6 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 23.8095 | 8 | no |
| GO:0006996 | organelle organization | 23.8095 | 4 | no |
| GO:0043933 | protein-containing complex organization | 23.8095 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 23.8095 | 4 | no |
| GO:0002181 | cytoplasmic translation | 23.8095 | 5 | no |
| GO:0006412 | translation | 23.8095 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 23.8095 | 4 | no |
| GO:0009966 | regulation of signal transduction | 23.8095 | 4 | no |
| GO:0010628 | positive regulation of gene expression | 21.4286 | 7 | yes |
| GO:0042127 | regulation of cell population proliferation | 21.4286 | 4 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 21.4286 | 6 | yes |
| GO:0065003 | protein-containing complex assembly | 21.4286 | 5 | no |
| GO:0080134 | regulation of response to stress | 21.4286 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.4286 | 5 | no |
| GO:0071310 | cellular response to organic substance | 21.4286 | 4 | no |
| GO:0141188 | nucleic acid catabolic process | 21.4286 | 5 | no |
| GO:0035196 | miRNA processing | 11.9048 | 8 | yes |
| GO:0070918 | regulatory ncRNA processing | 11.9048 | 7 | yes |
| GO:0031053 | primary miRNA processing | 9.5238 | 9 | yes |
| GO:0060966 | regulation of gene silencing by regulatory ncRNA | 7.1429 | 7 | yes |
| GO:0070920 | regulation of regulatory ncRNA processing | 7.1429 | 6 | yes |
| GO:0060147 | regulation of post-transcriptional gene silencing | 4.7619 | 7 | yes |
| GO:0060148 | positive regulation of post-transcriptional gene silencing | 4.7619 | 4 | yes |
| GO:0060964 | regulation of miRNA-mediated gene silencing | 4.7619 | 9 | yes |
| GO:0072091 | regulation of stem cell proliferation | 4.7619 | 5 | yes |
| GO:1900368 | regulation of post-transcriptional gene silencing by regulatory ncRNA | 4.7619 | 8 | yes |
| GO:1900370 | positive regulation of post-transcriptional gene silencing by RNA | 4.7619 | 5 | yes |
| GO:1903798 | regulation of miRNA processing | 4.7619 | 7 | yes |
| GO:1903800 | positive regulation of miRNA processing | 4.7619 | 7 | yes |
| GO:2000631 | regulation of pre-miRNA processing | 4.7619 | 8 | yes |
| GO:2000633 | positive regulation of pre-miRNA processing | 4.7619 | 8 | yes |
| GO:2000637 | positive regulation of miRNA-mediated gene silencing | 4.7619 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| NR2E1_HUMAN | [view interactions] | Low throughput | no | yes |
| RN168_HUMAN | [view interactions] | Low throughput | no | no |
| UBP51_HUMAN | [view interactions] | Low throughput | no | yes |
| MTA70_HUMAN | [view interactions] | Low throughput | no | no |
| RNC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DGCR8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DDX17_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| FUBP2_HUMAN | [view interactions] | Low throughput | no | yes |
| ERH_HUMAN | [view interactions] | Low throughput | no | yes |
| STAU2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAR1B_HUMAN | [view interactions] | High throughput | no | no |
| RBM28_HUMAN | [view interactions] | High throughput | no | yes |
| TDIF2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN771_HUMAN | [view interactions] | High throughput | no | no |
| NVL_HUMAN | [view interactions] | High throughput | no | no |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| DDX18_HUMAN | [view interactions] | High throughput | no | yes |
| PUM3_HUMAN | [view interactions] | High throughput | no | yes |
| SURF6_HUMAN | [view interactions] | High throughput | no | yes |
| FCF1_HUMAN | [view interactions] | High throughput | no | yes |
| PINX1_HUMAN | [view interactions] | High throughput | no | yes |
| SPT2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN646_HUMAN | [view interactions] | High throughput | no | yes |
| PK1IP_HUMAN | [view interactions] | High throughput | no | yes |
| RLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CENPH_HUMAN | [view interactions] | High throughput | no | yes |
| ZN777_HUMAN | [view interactions] | High throughput | no | yes |
| CTCF_HUMAN | [view interactions] | High throughput | no | yes |
| DHX30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NOL10_HUMAN | [view interactions] | High throughput | no | yes |
| RS13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| REPI1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2A2B_HUMAN | [view interactions] | High throughput | no | yes |
| RL10A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR12_HUMAN | [view interactions] | High throughput | no | yes |
| ZN668_HUMAN | [view interactions] | High throughput | no | yes |
| DDX56_HUMAN | [view interactions] | High throughput | no | yes |
| MK67I_HUMAN | [view interactions] | High throughput | no | yes |
| DDX54_HUMAN | [view interactions] | High throughput | no | yes |
| POP1_HUMAN | [view interactions] | High throughput | no | no |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HERC5_HUMAN | [view interactions] | High throughput | no | yes |
| NOC3L_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| RIGI_HUMAN | [view interactions] | High throughput | no | yes |
| CCD86_HUMAN | [view interactions] | High throughput | no | yes |
| NOP16_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF6_HUMAN | [view interactions] | High throughput | no | yes |
| MAGB2_HUMAN | [view interactions] | High throughput | no | no |
| HP1B3_HUMAN | [view interactions] | High throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GZF1_HUMAN | [view interactions] | High throughput | no | yes |
| ABC3F_HUMAN | [view interactions] | High throughput | no | no |
| PRD15_HUMAN | [view interactions] | High throughput | no | no |
| ZN770_HUMAN | [view interactions] | High throughput | no | yes |
| FBLN5_HUMAN | [view interactions] | High throughput | no | no |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CX001_HUMAN | [view interactions] | High throughput | no | no |
| ZN624_HUMAN | [view interactions] | High throughput | no | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZC3HA_HUMAN | [view interactions] | High throughput | no | yes |
| TAP26_HUMAN | [view interactions] | High throughput | no | yes |
| ZN512_HUMAN | [view interactions] | High throughput | no | yes |
| DDX50_HUMAN | [view interactions] | High throughput | no | yes |
| RBM19_HUMAN | [view interactions] | High throughput | no | yes |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CG050_HUMAN | [view interactions] | High throughput | no | yes |
| NIP7_HUMAN | [view interactions] | High throughput | no | yes |
| KCTD5_HUMAN | [view interactions] | High throughput | no | no |
| RRP15_HUMAN | [view interactions] | High throughput | no | yes |
| TRI56_HUMAN | [view interactions] | High throughput | no | yes |
| RL7L_HUMAN | [view interactions] | High throughput | no | no |
| SREK1_HUMAN | [view interactions] | High throughput | no | yes |
| ABT1_HUMAN | [view interactions] | High throughput | no | no |
| RS4Y2_HUMAN | [view interactions] | High throughput | no | no |
| RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRS1_HUMAN | [view interactions] | High throughput | no | yes |
| SSF1_HUMAN | [view interactions] | High throughput | no | yes |
| MBB1A_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| NKRF_HUMAN | [view interactions] | High throughput | no | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| NOP56_HUMAN | [view interactions] | High throughput | no | yes |
| TUT7_HUMAN | [view interactions] | High throughput | no | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLP24_HUMAN | [view interactions] | High throughput | no | yes |
| FGFP1_HUMAN | [view interactions] | High throughput | no | no |
| OASL_HUMAN | [view interactions] | High throughput | no | no |
| SAS10_HUMAN | [view interactions] | High throughput | no | yes |
| NGDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM34_HUMAN | [view interactions] | High throughput | no | yes |
| E41LB_HUMAN | [view interactions] | High throughput | no | yes |
| RBMX2_HUMAN | [view interactions] | High throughput | no | yes |
| NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| WDR74_HUMAN | [view interactions] | High throughput | no | no |
| IMP4_HUMAN | [view interactions] | High throughput | no | no |
| RRP1_HUMAN | [view interactions] | High throughput | no | yes |
| RPF1_HUMAN | [view interactions] | High throughput | no | yes |
| U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDK12_HUMAN | [view interactions] | High throughput | no | yes |
| BMS1_HUMAN | [view interactions] | High throughput | no | yes |
| NOP53_HUMAN | [view interactions] | High throughput | no | yes |
| LUC7L_HUMAN | [view interactions] | High throughput | no | yes |
| RL36L_HUMAN | [view interactions] | High throughput | no | no |
| NALP7_HUMAN | [view interactions] | High throughput | no | no |
| RNF8_HUMAN | [view interactions] | High throughput | no | yes |
| UBP36_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC6_HUMAN | [view interactions] | High throughput | no | yes |
| XRCC5_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP19_HUMAN | [view interactions] | High throughput | no | yes |
| FEN1_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| PRKDC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| MSH2_HUMAN | [view interactions] | High throughput | no | yes |
| MSH6_HUMAN | [view interactions] | High throughput | no | yes |
| DDB1_HUMAN | [view interactions] | High throughput | no | yes |
| CHK1_HUMAN | [view interactions] | High throughput | no | no |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| SMC5_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| MARE2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAT10_HUMAN | [view interactions] | High throughput | no | yes |
| PLEK2_HUMAN | [view interactions] | High throughput | no | no |
| RPRD2_HUMAN | [view interactions] | High throughput | no | yes |
| FLII_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDT1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI36_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| EWS_HUMAN | [view interactions] | High throughput | no | yes |
| DHX40_HUMAN | [view interactions] | High throughput | no | yes |
| TE2IP_HUMAN | [view interactions] | High throughput | no | yes |
| ARL14_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF15_HUMAN | [view interactions] | High throughput | no | no |
| TLN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEOX2_HUMAN | [view interactions] | High throughput | no | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TP53B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MDC1_HUMAN | [view interactions] | High throughput | no | yes |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| BIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| P5CR3_HUMAN | [view interactions] | High throughput | no | no |
| RAE1L_HUMAN | [view interactions] | High throughput | no | no |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRL1_HUMAN | [view interactions] | High throughput | no | yes |
| KIF11_HUMAN | [view interactions] | High throughput | no | yes |
| SYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTR9_HUMAN | [view interactions] | High throughput | no | yes |
| TFG_HUMAN | [view interactions] | High throughput | no | yes |
| ZWINT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KLF8_HUMAN | [view interactions] | High throughput | no | no |
| FANCI_HUMAN | [view interactions] | High throughput | no | yes |
| TET5A_HUMAN | [view interactions] | High throughput | no | yes |
| SMC6_HUMAN | [view interactions] | High throughput | no | no |
| HSF1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM3_HUMAN | [view interactions] | High throughput | no | no |
| NFYA_HUMAN | [view interactions] | High throughput | no | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| TMEDA_HUMAN | [view interactions] | High throughput | no | yes |
| SAM50_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RRP8_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF7_HUMAN | [view interactions] | High throughput | no | yes |
| CENPI_HUMAN | [view interactions] | High throughput | no | no |
| CENPR_HUMAN | [view interactions] | High throughput | no | yes |
| CENPO_HUMAN | [view interactions] | High throughput | no | no |
| SHQ1_HUMAN | [view interactions] | High throughput | no | no |
| CENPC_HUMAN | [view interactions] | High throughput | no | no |
| CENPN_HUMAN | [view interactions] | High throughput | no | no |
| CENPU_HUMAN | [view interactions] | High throughput | no | no |
| ZN189_HUMAN | [view interactions] | High throughput | no | yes |
| PAPD5_HUMAN | [view interactions] | High throughput | no | no |
| ZNF70_HUMAN | [view interactions] | High throughput | no | no |
| CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
| ZN483_HUMAN | [view interactions] | High throughput | no | no |
| ZN800_HUMAN | [view interactions] | High throughput | no | yes |
| NSA2_HUMAN | [view interactions] | High throughput | no | yes |
| NSD2_HUMAN | [view interactions] | High throughput | no | yes |
| NOG2_HUMAN | [view interactions] | High throughput | no | yes |
| RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BEND7_HUMAN | [view interactions] | High throughput | no | no |
| NMNA1_HUMAN | [view interactions] | High throughput | no | yes |
| RL26L_HUMAN | [view interactions] | High throughput | no | yes |
| DKC1_HUMAN | [view interactions] | High throughput | no | yes |
| TTF1_HUMAN | [view interactions] | High throughput | no | yes |
| DDX31_HUMAN | [view interactions] | High throughput | no | no |
| KNOP1_HUMAN | [view interactions] | High throughput | no | yes |
| BRX1_HUMAN | [view interactions] | High throughput | no | no |
| RALY_HUMAN | [view interactions] | High throughput | no | yes |
| GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
| MPP10_HUMAN | [view interactions] | High throughput | no | yes |
| Z324B_HUMAN | [view interactions] | High throughput | no | no |
| DDX24_HUMAN | [view interactions] | High throughput | no | yes |
| CC137_HUMAN | [view interactions] | High throughput | no | no |
| ZN689_HUMAN | [view interactions] | High throughput | no | yes |
| NOP2_HUMAN | [view interactions] | High throughput | no | yes |
| GLYR1_HUMAN | [view interactions] | High throughput | no | yes |
| ZFP62_HUMAN | [view interactions] | High throughput | no | no |
| DDX27_HUMAN | [view interactions] | High throughput | no | no |
| REXO4_HUMAN | [view interactions] | High throughput | no | yes |
| DDX10_HUMAN | [view interactions] | High throughput | no | yes |
| MECP2_HUMAN | [view interactions] | High throughput | no | yes |
| UTP23_HUMAN | [view interactions] | High throughput | no | no |
| ZCHC7_HUMAN | [view interactions] | High throughput | no | yes |
| RPF2_HUMAN | [view interactions] | High throughput | no | yes |
| TZAP_HUMAN | [view interactions] | High throughput | no | no |
| SPB1_HUMAN | [view interactions] | High throughput | no | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF22_HUMAN | [view interactions] | High throughput | no | yes |
| RL17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAK16_HUMAN | [view interactions] | High throughput | no | yes |