NGDN_HUMAN
Evidence for PS localization
Functions
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in NGDN_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 88.2353 | 4 | yes |
| GO:0003729 | mRNA binding | 20.5882 | 5 | no |
| GO:0019900 | kinase binding | 20.5882 | 4 | no |
| GO:0019901 | protein kinase binding | 20.5882 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in NGDN_HUMAN |
|---|---|---|---|---|
| GO:0009059 | macromolecule biosynthetic process | 67.6471 | 4 | no |
| GO:0002181 | cytoplasmic translation | 64.7059 | 5 | no |
| GO:0006412 | translation | 64.7059 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 64.7059 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 41.1765 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 38.2353 | 4 | yes |
| GO:0010468 | regulation of gene expression | 38.2353 | 6 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 38.2353 | 5 | yes |
| GO:0031323 | regulation of cellular metabolic process | 38.2353 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 38.2353 | 5 | yes |
| GO:0080090 | regulation of primary metabolic process | 38.2353 | 4 | yes |
| GO:0090304 | nucleic acid metabolic process | 38.2353 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 38.2353 | 4 | no |
| GO:0022607 | cellular component assembly | 35.2941 | 4 | no |
| GO:0006396 | RNA processing | 32.3529 | 6 | yes |
| GO:0016070 | RNA metabolic process | 32.3529 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 32.3529 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 32.3529 | 4 | no |
| GO:0022613 | ribonucleoprotein complex biogenesis | 29.4118 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 29.4118 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.4118 | 5 | no |
| GO:0043933 | protein-containing complex organization | 29.4118 | 4 | no |
| GO:0010646 | regulation of cell communication | 26.4706 | 4 | yes |
| GO:0042274 | ribosomal small subunit biogenesis | 26.4706 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 26.4706 | 5 | yes |
| GO:0141188 | nucleic acid catabolic process | 26.4706 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.4706 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 26.4706 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.4706 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 26.4706 | 5 | no |
| GO:0006364 | rRNA processing | 23.5294 | 6 | yes |
| GO:0016072 | rRNA metabolic process | 23.5294 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 23.5294 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 23.5294 | 6 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.5294 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 23.5294 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 23.5294 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 23.5294 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.5294 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 20.5882 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 20.5882 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 20.5882 | 5 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 20.5882 | 6 | no |
| GO:0010608 | post-transcriptional regulation of gene expression | 14.7059 | 7 | yes |
| GO:0006417 | regulation of translation | 11.7647 | 6 | yes |
| GO:0030490 | maturation of SSU-rRNA | 11.7647 | 7 | yes |
| GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 8.8235 | 8 | yes |
| GO:0050804 | modulation of chemical synaptic transmission | 8.8235 | 5 | yes |
| GO:0099177 | regulation of trans-synaptic signaling | 8.8235 | 4 | yes |
| GO:0099170 | postsynaptic modulation of chemical synaptic transmission | 5.8824 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| H13_HUMAN | [view interactions] | High throughput | no | no |
| RS9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OASL_HUMAN | [view interactions] | High throughput | no | no |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RED1_HUMAN | [view interactions] | High throughput | no | no |
| GLI4_HUMAN | [view interactions] | High throughput | no | no |
| SRSF6_HUMAN | [view interactions] | High throughput | no | yes |
| FGFP1_HUMAN | [view interactions] | High throughput | no | no |
| ZN467_HUMAN | [view interactions] | High throughput | no | no |
| FGF13_HUMAN | [view interactions] | High throughput | no | no |
| ABC3C_HUMAN | [view interactions] | High throughput | no | no |
| RL17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2AB2_HUMAN | [view interactions] | High throughput | no | no |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRP14_HUMAN | [view interactions] | High throughput | no | no |
| H1FNT_HUMAN | [view interactions] | High throughput | no | yes |
| RBM19_HUMAN | [view interactions] | High throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KALM_HUMAN | [view interactions] | High throughput | no | no |
| TPX2_HUMAN | [view interactions] | High throughput | no | yes |
| NAT10_HUMAN | [view interactions] | High throughput | no | yes |
| ABT1_HUMAN | [view interactions] | High throughput | no | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF1_HUMAN | [view interactions] | High throughput | no | yes |
| KRR1_HUMAN | [view interactions] | High throughput | no | yes |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| H2A1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN574_HUMAN | [view interactions] | High throughput | no | yes |
| DDX10_HUMAN | [view interactions] | High throughput | no | yes |
| ZN346_HUMAN | [view interactions] | High throughput | no | yes |
| DGCR8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LN28A_HUMAN | [view interactions] | High throughput | no | no |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEIL1_HUMAN | [view interactions] | High throughput | no | yes |
| ESF1_HUMAN | [view interactions] | High throughput | no | yes |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM4B_HUMAN | [view interactions] | High throughput | no | yes |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| DOT1L_HUMAN | [view interactions] | High throughput | no | yes |
| ACE2_HUMAN | [view interactions] | High throughput | no | no |
| VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| UBP36_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP1_HUMAN | [view interactions] | High throughput | no | yes |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAS10_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| MNDA_HUMAN | [view interactions] | High throughput | no | no |
| RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| AATF_HUMAN | [view interactions] | High throughput | no | yes |
| MOT1_HUMAN | [view interactions] | High throughput | no | no |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KGP1_HUMAN | [view interactions] | High throughput | no | yes |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| NOM1_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| H11_HUMAN | [view interactions] | High throughput | no | no |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| BECN1_HUMAN | [view interactions] | High throughput | no | yes |
| KPCD2_HUMAN | [view interactions] | High throughput | no | yes |
| BORA_HUMAN | [view interactions] | High throughput | no | yes |
| KLC3_HUMAN | [view interactions] | High throughput | no | no |
| NOL10_HUMAN | [view interactions] | High throughput | no | yes |
| ZN512_HUMAN | [view interactions] | High throughput | no | yes |
| H1T_HUMAN | [view interactions] | High throughput | no | no |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WDR46_HUMAN | [view interactions] | High throughput | no | yes |
| FOXA1_HUMAN | [view interactions] | High throughput | no | no |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| CHD3_HUMAN | [view interactions] | High throughput | no | yes |
| RIOK1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| DCPS_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| CPSF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ZCH18_HUMAN | [view interactions] | High throughput | no | yes |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| NMRL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |