Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

TP53B_HUMAN

Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed, PubMed, PubMed, PubMed, PubMed, PubMed). Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1 (PubMed, PubMed, PubMed). In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs sites (PubMed). Recruited to DSBs sites by recognizing and binding histone H2A monoubiquitinated at Lys-15 (H2AK15Ub) and histone H4 dimethylated at Lys-20 (H4K20me2), two histone marks that are present at DSBs sites (PubMed, PubMed, PubMed). Required for immunoglobulin class-switch recombination (CSR) during antibody genesis, a process that involves the generation of DNA DSBs (PubMed). Participates in the repair and the orientation of the broken DNA ends during CSR . In contrast, it is not required for classic NHEJ and V(D)J recombination . Promotes NHEJ of dysfunctional telomeres via interaction with PAXIP1 (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in TP53B_HUMAN
GO:0003723 RNA binding 40.2299 4 no
GO:0017076 purine nucleotide binding 22.9885 4 no
GO:0032555 purine ribonucleotide binding 22.9885 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.9885 4 no
GO:0005524 ATP binding 21.8391 5 no
GO:0030554 adenyl nucleotide binding 21.8391 5 no
GO:0032559 adenyl ribonucleotide binding 21.8391 5 no
GO:0046872 metal ion binding 21.8391 4 no
GO:0003677 DNA binding 18.3908 4 yes
GO:0043565 sequence-specific DNA binding 10.3448 5 yes
GO:0140297 DNA-binding transcription factor binding 9.1954 4 yes
GO:0042162 telomeric DNA binding 5.7471 6 yes
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5.7471 5 yes
GO:0003684 damaged DNA binding 3.4483 5 yes
GO:0035064 methylated histone binding 3.4483 4 yes
GO:0140034 methylation-dependent protein binding 3.4483 4 yes
GO:0061649 ubiquitin modification-dependent histone binding 2.2989 4 yes
GO:0140035 ubiquitination-like modification-dependent protein binding 2.2989 4 yes
GO:0140036 ubiquitin-dependent protein binding 2.2989 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in TP53B_HUMAN
GO:0080090 regulation of primary metabolic process 60.9195 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 59.7701 4 yes
GO:0060255 regulation of macromolecule metabolic process 59.7701 4 yes
GO:0031323 regulation of cellular metabolic process 57.4713 4 yes
GO:0048522 positive regulation of cellular process 54.0230 4 yes
GO:0048523 negative regulation of cellular process 51.7241 4 yes
GO:0009893 positive regulation of metabolic process 49.4253 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 45.9770 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 44.8276 5 yes
GO:0010468 regulation of gene expression 44.8276 5 yes
GO:0051246 regulation of protein metabolic process 43.6782 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 43.6782 5 yes
GO:0031325 positive regulation of cellular metabolic process 42.5287 5 yes
GO:0009889 regulation of biosynthetic process 39.0805 4 yes
GO:0031326 regulation of cellular biosynthetic process 39.0805 5 yes
GO:0009892 negative regulation of metabolic process 37.9310 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 37.9310 5 yes
GO:0010646 regulation of cell communication 36.7816 4 no
GO:0006996 organelle organization 35.6322 4 no
GO:0043412 macromolecule modification 35.6322 4 no
GO:0051128 regulation of cellular component organization 35.6322 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 34.4828 5 yes
GO:0051252 regulation of RNA metabolic process 34.4828 5 yes
GO:0090304 nucleic acid metabolic process 34.4828 4 yes
GO:0036211 protein modification process 34.4828 4 no
GO:0009966 regulation of signal transduction 34.4828 4 no
GO:0010605 negative regulation of macromolecule metabolic process 34.4828 5 yes
GO:0031324 negative regulation of cellular metabolic process 34.4828 5 yes
GO:0051247 positive regulation of protein metabolic process 33.3333 6 no
GO:0022607 cellular component assembly 32.1839 4 yes
GO:0048584 positive regulation of response to stimulus 31.0345 4 yes
GO:1903506 regulation of nucleic acid-templated transcription 28.7356 7 yes
GO:2001141 regulation of RNA biosynthetic process 28.7356 6 yes
GO:0031399 regulation of protein modification process 28.7356 6 no
GO:0006355 regulation of DNA-templated transcription 28.7356 6 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 27.5862 6 yes
GO:0080134 regulation of response to stress 26.4368 4 yes
GO:0009894 regulation of catabolic process 26.4368 4 no
GO:0006796 phosphate-containing compound metabolic process 25.2874 4 no
GO:0080135 regulation of cellular response to stress 24.1379 4 yes
GO:0010941 regulation of cell death 24.1379 4 no
GO:0009891 positive regulation of biosynthetic process 24.1379 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 24.1379 6 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 22.9885 6 yes
GO:0010647 positive regulation of cell communication 22.9885 5 no
GO:0023056 positive regulation of signaling 22.9885 4 no
GO:0006357 regulation of transcription by RNA polymerase II 22.9885 7 yes
GO:0033043 regulation of organelle organization 21.8391 5 no
GO:1902531 regulation of intracellular signal transduction 21.8391 5 no
GO:0019220 regulation of phosphate metabolic process 21.8391 6 no
GO:0051174 regulation of phosphorus metabolic process 21.8391 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.8391 6 yes
GO:0051052 regulation of DNA metabolic process 20.6897 5 yes
GO:0016070 RNA metabolic process 20.6897 5 no
GO:0048585 negative regulation of response to stimulus 19.5402 4 yes
GO:0006259 DNA metabolic process 18.3908 4 yes
GO:0006974 cellular response to DNA damage stimulus 18.3908 4 yes
GO:0010628 positive regulation of gene expression 18.3908 6 yes
GO:0043933 protein-containing complex organization 17.2414 4 yes
GO:0051054 positive regulation of DNA metabolic process 16.0920 6 yes
GO:0051254 positive regulation of RNA metabolic process 16.0920 6 yes
GO:0045893 positive regulation of DNA-templated transcription 14.9425 7 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 14.9425 8 yes
GO:0065003 protein-containing complex assembly 14.9425 5 yes
GO:1902680 positive regulation of RNA biosynthetic process 14.9425 7 yes
GO:1903508 positive regulation of nucleic acid-templated transcription 14.9425 8 yes
GO:0006281 DNA repair 14.9425 5 yes
GO:0051094 positive regulation of developmental process 12.6437 4 yes
GO:2001020 regulation of response to DNA damage stimulus 12.6437 5 yes
GO:0050776 regulation of immune response 11.4943 4 yes
GO:0051240 positive regulation of multicellular organismal process 11.4943 4 yes
GO:0006302 double-strand break repair 11.4943 6 yes
GO:0051726 regulation of cell cycle 10.3448 4 yes
GO:0002684 positive regulation of immune system process 9.1954 4 yes
GO:0006282 regulation of DNA repair 9.1954 6 yes
GO:0050778 positive regulation of immune response 8.0460 5 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 8.0460 4 yes
GO:0051259 protein complex oligomerization 8.0460 6 yes
GO:2000779 regulation of double-strand break repair 8.0460 7 yes
GO:0010564 regulation of cell cycle process 8.0460 5 yes
GO:0000018 regulation of DNA recombination 6.8966 6 yes
GO:0051053 negative regulation of DNA metabolic process 5.7471 6 yes
GO:0051260 protein homooligomerization 5.7471 7 yes
GO:0006303 double-strand break repair via nonhomologous end joining 5.7471 7 yes
GO:0045786 negative regulation of cell cycle 4.5977 5 yes
GO:0045911 positive regulation of DNA recombination 4.5977 7 yes
GO:0050865 regulation of cell activation 4.5977 4 yes
GO:0050867 positive regulation of cell activation 4.5977 5 yes
GO:0051249 regulation of lymphocyte activation 4.5977 5 yes
GO:0051251 positive regulation of lymphocyte activation 4.5977 6 yes
GO:0071478 cellular response to radiation 4.5977 4 yes
GO:1901987 regulation of cell cycle phase transition 4.5977 6 yes
GO:1901988 negative regulation of cell cycle phase transition 4.5977 7 yes
GO:0002694 regulation of leukocyte activation 4.5977 4 yes
GO:0002696 positive regulation of leukocyte activation 4.5977 5 yes
GO:0010212 response to ionizing radiation 4.5977 4 yes
GO:0010569 regulation of double-strand break repair via homologous recombination 4.5977 7 yes
GO:0010948 negative regulation of cell cycle process 4.5977 6 yes
GO:0042770 signal transduction in response to DNA damage 3.4483 4 yes
GO:2001021 negative regulation of response to DNA damage stimulus 3.4483 5 yes
GO:0000075 cell cycle checkpoint signaling 3.4483 4 yes
GO:0000077 DNA damage checkpoint signaling 3.4483 5 yes
GO:0002697 regulation of immune effector process 3.4483 4 yes
GO:0002699 positive regulation of immune effector process 3.4483 5 yes
GO:0002703 regulation of leukocyte mediated immunity 3.4483 5 yes
GO:0002705 positive regulation of leukocyte mediated immunity 3.4483 6 yes
GO:0002706 regulation of lymphocyte mediated immunity 3.4483 6 yes
GO:0002708 positive regulation of lymphocyte mediated immunity 3.4483 7 yes
GO:0002819 regulation of adaptive immune response 3.4483 5 yes
GO:0002821 positive regulation of adaptive immune response 3.4483 6 yes
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.4483 6 yes
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 3.4483 7 yes
GO:0031570 DNA integrity checkpoint signaling 3.4483 5 yes
GO:0045191 regulation of isotype switching 2.2989 7 yes
GO:0045738 negative regulation of DNA repair 2.2989 6 yes
GO:0045830 positive regulation of isotype switching 2.2989 5 yes
GO:0045910 negative regulation of DNA recombination 2.2989 7 yes
GO:0050864 regulation of B cell activation 2.2989 6 yes
GO:0050871 positive regulation of B cell activation 2.2989 7 yes
GO:0071479 cellular response to ionizing radiation 2.2989 5 yes
GO:0071481 cellular response to X-ray 2.2989 6 yes
GO:2000042 negative regulation of double-strand break repair via homologous recombination 2.2989 8 yes
GO:2000780 negative regulation of double-strand break repair 2.2989 7 yes
GO:0002637 regulation of immunoglobulin production 2.2989 6 yes
GO:0002639 positive regulation of immunoglobulin production 2.2989 7 yes
GO:0002700 regulation of production of molecular mediator of immune response 2.2989 5 yes
GO:0002702 positive regulation of production of molecular mediator of immune response 2.2989 6 yes
GO:0002712 regulation of B cell mediated immunity 2.2989 7 yes
GO:0002714 positive regulation of B cell mediated immunity 2.2989 8 yes
GO:0002889 regulation of immunoglobulin mediated immune response 2.2989 8 yes
GO:0002891 positive regulation of immunoglobulin mediated immune response 2.2989 9 yes
GO:0010165 response to X-ray 2.2989 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in TP53B_HUMAN
DOID:1289 neurodegenerative disease 2.2989 4 no
DOID:331 central nervous system disease 2.2989 3 no
DOID:114 heart disease 2.2989 3 no
DOID:65 connective tissue disease 2.2989 3 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RAD50_HUMAN [view interactions] Low throughput no yes
RFA1_HUMAN [view interactions] Low throughput no yes
PPP5_HUMAN [view entry] [view interactions] Low throughput yes yes
DCR1A_HUMAN [view interactions] Low throughput no yes
NFKB1_HUMAN [view interactions] Low throughput no yes
E2F1_HUMAN [view interactions] Low throughput no yes
HDAC4_HUMAN [view interactions] Low throughput no yes
NCOA3_HUMAN [view interactions] Low throughput no yes
UB2L3_HUMAN [view interactions] Low throughput no yes
MSL1_HUMAN [view interactions] Low throughput no yes
TIRR_HUMAN [view interactions] Low throughput no no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
BUB1_HUMAN [view interactions] Low throughput no no
KAT8_HUMAN [view interactions] Low throughput no no
LMNA_HUMAN [view entry] [view interactions] Low throughput yes yes
UBE4A_HUMAN [view entry] [view interactions] Low throughput yes yes
KDM2A_HUMAN [view interactions] Low throughput no yes
E2F4_HUMAN [view interactions] Low throughput no no
RBL1_HUMAN [view interactions] Low throughput no yes
RBL2_HUMAN [view interactions] Low throughput no yes
EXOC4_HUMAN [view entry] [view interactions] Low throughput yes yes
ESR1_HUMAN [view interactions] Low throughput no no
TP53B_HUMAN [view entry] [view interactions] Low throughput yes yes
RAD51_HUMAN [view interactions] Low throughput no yes
PELI1_HUMAN [view interactions] Low throughput no yes
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTEN_HUMAN [view entry] [view interactions] Low throughput yes yes
BIRC5_HUMAN [view interactions] Low throughput no no
SPOP_HUMAN [view interactions] Low throughput no no
NPL4_HUMAN [view interactions] Low throughput no yes
PALB2_HUMAN [view interactions] Low throughput no yes
P53_HUMAN [view interactions] Low throughput no no
TFDP1_HUMAN [view interactions] Low throughput no yes
H4_HUMAN [view interactions] Low throughput no yes
KDM1A_HUMAN [view interactions] Low throughput no yes
UBP28_HUMAN [view interactions] Low throughput no yes
IMA1_HUMAN [view entry] [view interactions] Low throughput yes yes
PAXI1_HUMAN [view interactions] Low throughput no no
CDK1_HUMAN [view interactions] Low throughput no no
CCNB1_HUMAN [view interactions] Low throughput no no
CHK1_HUMAN [view interactions] Low throughput no no
NUD16_HUMAN [view interactions] Low throughput no yes
PARP1_HUMAN [view entry] [view interactions] Low throughput yes yes
PIAS4_HUMAN [view interactions] Low throughput no yes
MCPH1_HUMAN [view interactions] Low throughput no yes
QORX_HUMAN [view interactions] Low throughput no yes
KMT5A_HUMAN [view interactions] Low throughput no no
SIR3_HUMAN [view interactions] Low throughput no yes
SHLD1_HUMAN [view interactions] Low throughput no yes
KIFA3_HUMAN [view entry] [view interactions] Low throughput yes yes
PML_HUMAN [view interactions] Low throughput no yes
DYL1_HUMAN [view entry] [view interactions] Low throughput yes no
SCAI_HUMAN [view entry] [view interactions] Low throughput yes yes
SUMO1_HUMAN [view interactions] Low throughput no yes
H31_HUMAN [view interactions] Low throughput no yes
MDC1_HUMAN [view interactions] Low throughput no yes
H2B1C_HUMAN [view interactions] Low throughput no yes
H2AX_HUMAN [view interactions] Low throughput no yes
ZNHI1_HUMAN [view interactions] Low throughput no yes
VRK1_HUMAN [view interactions] Low throughput no yes
NCOA6_HUMAN [view interactions] Low throughput no yes
PLK1_HUMAN [view interactions] Low throughput no yes
H2A1_HUMAN [view interactions] Low throughput no yes
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
TIF1B_HUMAN [view interactions] Low throughput no yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
BRCA1_HUMAN [view interactions] Low throughput no yes
RB_HUMAN [view interactions] Low throughput no yes
RNF8_HUMAN [view interactions] Low throughput no yes
TOPB1_HUMAN [view interactions] Low throughput no yes
H2A2A_HUMAN [view interactions] Low throughput no yes
H2A1B_HUMAN [view interactions] Low throughput no yes
H2A1D_HUMAN [view interactions] Low throughput no yes
H2A1A_HUMAN [view interactions] Low throughput no yes
H2AJ_HUMAN [view interactions] Low throughput no yes
H2A3_HUMAN [view interactions] Low throughput no yes
H2A2B_HUMAN [view interactions] Low throughput no yes
UBC9_HUMAN [view interactions] Low throughput no yes
H2A1J_HUMAN [view interactions] Low throughput no yes
H2A1C_HUMAN [view interactions] Low throughput no yes
H2A1H_HUMAN [view interactions] Low throughput no yes
H2A2C_HUMAN [view interactions] Low throughput no yes
PNKP_HUMAN [view interactions] Low throughput no yes
TERF2_HUMAN [view interactions] Low throughput no yes
ASH2L_HUMAN [view interactions] Low throughput no yes
KMT2B_HUMAN [view interactions] Low throughput no no
TERF1_HUMAN [view interactions] Low throughput no no
RAD18_HUMAN [view interactions] Low throughput no yes
BRCA2_HUMAN [view interactions] Low throughput no no
TERA_HUMAN [view entry] [view interactions] Low throughput yes yes
MD2L2_HUMAN [view interactions] Low throughput no yes
UIMC1_HUMAN [view interactions] Low throughput no no
RN168_HUMAN [view interactions] Low throughput no no
SHLD3_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
RIF1_HUMAN [view interactions] Low throughput no yes
BLM_HUMAN [view interactions] Low throughput no yes
ARAP1_HUMAN [view interactions] Low throughput no yes
RFA2_HUMAN [view interactions] Low throughput no yes
CSN5_HUMAN [view interactions] Low throughput no yes
NBN_HUMAN [view interactions] Low throughput no yes
PSMD8_HUMAN [view interactions] High throughput no yes
SDHB_HUMAN [view interactions] High throughput no yes
MSD3_HUMAN [view interactions] High throughput no no
JIP4_HUMAN [view interactions] High throughput no yes
CT453_HUMAN [view interactions] High throughput no no
GLTL5_HUMAN [view interactions] High throughput no yes
AEN_HUMAN [view interactions] High throughput no no
T2H2L_HUMAN [view interactions] High throughput no no
ANS1A_HUMAN [view interactions] High throughput no yes
ZZZ3_HUMAN [view interactions] High throughput no yes
CREB5_HUMAN [view interactions] High throughput no no
ZN609_HUMAN [view interactions] High throughput no yes
ZIC4_HUMAN [view interactions] High throughput no yes
ZN106_HUMAN [view interactions] High throughput no no
ZHX2_HUMAN [view interactions] High throughput no yes
ZFR_HUMAN [view interactions] High throughput no yes
EP300_HUMAN [view interactions] High throughput no yes
ZC3H1_HUMAN [view interactions] High throughput no yes
ZC3H4_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
ZBTB9_HUMAN [view interactions] High throughput no no
P5F1B_HUMAN [view interactions] High throughput no no
ZBT25_HUMAN [view interactions] High throughput no no
PO5F1_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
NMDZ1_HUMAN [view entry] [view interactions] High throughput yes yes
FL2D_HUMAN [view interactions] High throughput no yes
AAMP_HUMAN [view interactions] High throughput no yes
WDR26_HUMAN [view interactions] High throughput no yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
INT14_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
UPP1_HUMAN [view interactions] High throughput no no
CDC27_HUMAN [view interactions] High throughput no yes
TSYL1_HUMAN [view interactions] High throughput no yes
ARI3A_HUMAN [view interactions] High throughput no yes
TRM2A_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
TRM1L_HUMAN [view interactions] High throughput no yes
FLNA_HUMAN [view entry] [view interactions] High throughput yes no
TRI22_HUMAN [view interactions] High throughput no yes
IMA5_HUMAN [view entry] [view interactions] High throughput yes yes
TOPRS_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
THOC7_HUMAN [view interactions] High throughput no yes
IMA4_HUMAN [view interactions] High throughput no yes
THOC2_HUMAN [view interactions] High throughput no yes
MCM6_HUMAN [view interactions] High throughput no yes
TEX10_HUMAN [view interactions] High throughput no no
NUMA1_HUMAN [view interactions] High throughput no yes
HTF4_HUMAN [view interactions] High throughput no yes
PIMT_HUMAN [view entry] [view interactions] High throughput yes yes
ELOB_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
TAF6L_HUMAN [view interactions] High throughput no yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
TAF5L_HUMAN [view interactions] High throughput no no
PRS8_HUMAN [view interactions] High throughput no yes
RBP56_HUMAN [view interactions] High throughput no yes
PTN9_HUMAN [view interactions] High throughput no yes
TAF10_HUMAN [view interactions] High throughput no yes
REQU_HUMAN [view interactions] High throughput no yes
TADA3_HUMAN [view interactions] High throughput no yes
RFC2_HUMAN [view interactions] High throughput no yes
TADA1_HUMAN [view interactions] High throughput no yes
SAFB1_HUMAN [view interactions] High throughput no yes
CREST_HUMAN [view interactions] High throughput no yes
SRSF1_HUMAN [view interactions] High throughput no yes
SRRT_HUMAN [view interactions] High throughput no yes
LAP2A_HUMAN [view interactions] High throughput no yes
SPNXB_HUMAN [view interactions] High throughput no no
P73_HUMAN [view interactions] High throughput no no
SP110_HUMAN [view interactions] High throughput no no
TRPS1_HUMAN [view interactions] High throughput no no
SP100_HUMAN [view interactions] High throughput no no
DNJC7_HUMAN [view interactions] High throughput no yes
SNPC1_HUMAN [view interactions] High throughput no no
XRCC5_HUMAN [view interactions] High throughput no yes
SLX4I_HUMAN [view interactions] High throughput no yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
SN12L_HUMAN [view interactions] High throughput no no
DEK_HUMAN [view interactions] High throughput no yes
SIN3A_HUMAN [view interactions] High throughput no yes
HAT1_HUMAN [view interactions] High throughput no yes
SET1A_HUMAN [view interactions] High throughput no yes
CDC23_HUMAN [view interactions] High throughput no yes
SP130_HUMAN [view interactions] High throughput no no
CDC16_HUMAN [view interactions] High throughput no yes
SAGE1_HUMAN [view interactions] High throughput no no
MTA2_HUMAN [view interactions] High throughput no yes
INT3_HUMAN [view interactions] High throughput no yes
APC10_HUMAN [view interactions] High throughput no yes
MCES_HUMAN [view interactions] High throughput no yes
RACK1_HUMAN [view interactions] High throughput no yes
MCE1_HUMAN [view interactions] High throughput no yes
PUR6_HUMAN [view entry] [view interactions] High throughput yes yes
RFX2_HUMAN [view interactions] High throughput no no
ML12A_HUMAN [view interactions] High throughput no no
RBM5_HUMAN [view interactions] High throughput no yes
NUDC_HUMAN [view interactions] High throughput no yes
RBM26_HUMAN [view interactions] High throughput no yes
STRAP_HUMAN [view entry] [view interactions] High throughput yes yes
RBM10_HUMAN [view interactions] High throughput no yes
CBX3_HUMAN [view interactions] High throughput no yes
ARIP4_HUMAN [view interactions] High throughput no yes
CLAP2_HUMAN [view entry] [view interactions] High throughput yes no
PGH1_HUMAN [view interactions] High throughput no yes
RCOR1_HUMAN [view interactions] High throughput no yes
PSME3_HUMAN [view interactions] High throughput no yes
SUN2_HUMAN [view interactions] High throughput no yes
PSMD6_HUMAN [view interactions] High throughput no yes
DRS7B_HUMAN [view entry] [view interactions] High throughput yes yes
PSMD4_HUMAN [view interactions] High throughput no yes
CYBP_HUMAN [view entry] [view interactions] High throughput yes yes
PSD13_HUMAN [view interactions] High throughput no yes
ANC2_HUMAN [view interactions] High throughput no no
PRS6B_HUMAN [view interactions] High throughput no yes
APC4_HUMAN [view interactions] High throughput no yes
PRS6A_HUMAN [view entry] [view interactions] High throughput yes yes
APC5_HUMAN [view interactions] High throughput no yes
PRS4_HUMAN [view entry] [view interactions] High throughput yes yes
APC7_HUMAN [view interactions] High throughput no yes
PRR12_HUMAN [view entry] [view interactions] High throughput yes yes
PELO_HUMAN [view interactions] High throughput no yes
PRCC_HUMAN [view interactions] High throughput no yes
UGGG1_HUMAN [view interactions] High throughput no yes
PRAME_HUMAN [view interactions] High throughput no no
BEND3_HUMAN [view interactions] High throughput no yes
PP1R8_HUMAN [view interactions] High throughput no yes
APC1_HUMAN [view interactions] High throughput no no
PP1RA_HUMAN [view interactions] High throughput no yes
ZBT10_HUMAN [view interactions] High throughput no yes
PPM1G_HUMAN [view interactions] High throughput no no
APC16_HUMAN [view interactions] High throughput no yes
PARN_HUMAN [view entry] [view interactions] High throughput yes yes
FLCN_HUMAN [view interactions] High throughput no yes
OGT1_HUMAN [view entry] [view interactions] High throughput yes yes
SMRD3_HUMAN [view interactions] High throughput no no
ENOA_HUMAN [view entry] [view interactions] High throughput yes yes
CPSF5_HUMAN [view interactions] High throughput no yes
GLYM_HUMAN [view entry] [view interactions] High throughput yes yes
NSUN2_HUMAN [view interactions] High throughput no yes
MOV10_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
NXF1_HUMAN [view interactions] High throughput no yes
NR2C1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
NOVA1_HUMAN [view interactions] High throughput no yes
THA10_HUMAN [view interactions] High throughput no no
NOSIP_HUMAN [view interactions] High throughput no yes
NUP50_HUMAN [view interactions] High throughput no yes
NFIC_HUMAN [view interactions] High throughput no yes
TAF1_HUMAN [view interactions] High throughput no yes
NELFB_HUMAN [view interactions] High throughput no no
TYK2_HUMAN [view interactions] High throughput no no
NCOR2_HUMAN [view interactions] High throughput no yes
WBP2_HUMAN [view interactions] High throughput no yes
MORC3_HUMAN [view interactions] High throughput no yes
MED9_HUMAN [view interactions] High throughput no no
CAF1A_HUMAN [view interactions] High throughput no yes
MED8_HUMAN [view interactions] High throughput no yes
PCGF1_HUMAN [view interactions] High throughput no yes
MED7_HUMAN [view interactions] High throughput no no
DPPA4_HUMAN [view interactions] High throughput no no
SF3B1_HUMAN [view interactions] High throughput no yes
NANOG_HUMAN [view interactions] High throughput no no
MED6_HUMAN [view interactions] High throughput no yes
NFAC2_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
RT07_HUMAN [view interactions] High throughput no yes
MED31_HUMAN [view interactions] High throughput no yes
MED30_HUMAN [view interactions] High throughput no no
MED27_HUMAN [view interactions] High throughput no yes
SUMO2_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
MED25_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
MED22_HUMAN [view interactions] High throughput no no
SPDLY_HUMAN [view interactions] High throughput no yes
SMCE1_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
MED20_HUMAN [view interactions] High throughput no no
MED18_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
MED17_HUMAN [view interactions] High throughput no no
TNR6A_HUMAN [view interactions] High throughput no yes
MED15_HUMAN [view interactions] High throughput no yes
H2B1B_HUMAN [view interactions] High throughput no yes
ILF3_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
MED14_HUMAN [view interactions] High throughput no no
MD13L_HUMAN [view interactions] High throughput no no
MED13_HUMAN [view interactions] High throughput no no
MED12_HUMAN [view interactions] High throughput no yes
MED10_HUMAN [view interactions] High throughput no no
MED1_HUMAN [view interactions] High throughput no no
MDN1_HUMAN [view interactions] High throughput no no
MBNL1_HUMAN [view interactions] High throughput no yes
SNF5_HUMAN [view interactions] High throughput no yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
HIRA_HUMAN [view interactions] High throughput no yes
LSM4_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
LSM3_HUMAN [view interactions] High throughput no yes
TZAP_HUMAN [view interactions] High throughput no no
KAT2A_HUMAN [view interactions] High throughput no no
DDX58_HUMAN [view interactions] High throughput no yes
INT9_HUMAN [view interactions] High throughput no no
SKA3_HUMAN [view interactions] High throughput no no
IF16_HUMAN [view interactions] High throughput no no
DYL2_HUMAN [view entry] [view interactions] High throughput yes no
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
CDKN3_HUMAN [view interactions] High throughput no no
HNRDL_HUMAN [view interactions] High throughput no yes
MECP2_HUMAN [view interactions] High throughput no yes
HNRPD_HUMAN [view entry] [view interactions] High throughput yes yes
SLN11_HUMAN [view interactions] High throughput no yes
ROAA_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
SIR6_HUMAN [view interactions] High throughput no yes
TF3C5_HUMAN [view interactions] High throughput no yes
TF3C4_HUMAN [view interactions] High throughput no no
TF3C3_HUMAN [view interactions] High throughput no no
RBCC1_HUMAN [view interactions] High throughput no no
TF3C1_HUMAN [view interactions] High throughput no yes
GT2D1_HUMAN [view interactions] High throughput no yes
GEMI4_HUMAN [view interactions] High throughput no yes
NEK1_HUMAN [view interactions] High throughput no yes
FUBP1_HUMAN [view interactions] High throughput no yes
ITB3_HUMAN [view entry] [view interactions] High throughput yes no
XRCC1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX22_HUMAN [view interactions] High throughput no no
LRRK2_HUMAN [view interactions] High throughput no yes
TRI33_HUMAN [view interactions] High throughput no yes
SMC6_HUMAN [view interactions] High throughput no no
SMRC2_HUMAN [view interactions] High throughput no yes
RM11_HUMAN [view interactions] High throughput no yes
SARDH_HUMAN [view interactions] High throughput no yes
RHG17_HUMAN [view interactions] High throughput no no
FA98B_HUMAN [view interactions] High throughput no yes
ZBT11_HUMAN [view interactions] High throughput no yes
RAMAC_HUMAN [view interactions] High throughput no yes
P5CR3_HUMAN [view interactions] High throughput no no
SMRD1_HUMAN [view interactions] High throughput no yes
CHAP1_HUMAN [view interactions] High throughput no yes
EXOS5_HUMAN [view interactions] High throughput no yes
CENPF_HUMAN [view interactions] High throughput no no
EGR3_HUMAN [view interactions] High throughput no yes
ARK72_HUMAN [view entry] [view interactions] High throughput yes yes
ILF2_HUMAN [view interactions] High throughput no yes
ZSWM9_HUMAN [view interactions] High throughput no no
DPY30_HUMAN [view interactions] High throughput no yes
PSMD2_HUMAN [view entry] [view interactions] High throughput yes yes
DNPEP_HUMAN [view interactions] High throughput no yes
ERGI1_HUMAN [view interactions] High throughput no yes
RRP44_HUMAN [view interactions] High throughput no yes
NU107_HUMAN [view interactions] High throughput no no
ZN281_HUMAN [view interactions] High throughput no no
CCNT1_HUMAN [view interactions] High throughput no yes
PRP16_HUMAN [view interactions] High throughput no yes
THIM_HUMAN [view interactions] High throughput no yes
DDX46_HUMAN [view interactions] High throughput no yes
RPAC1_HUMAN [view interactions] High throughput no no
DDX42_HUMAN [view interactions] High throughput no yes
TCP4_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
TRI14_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
DDX20_HUMAN [view interactions] High throughput no no
POTE1_HUMAN [view interactions] High throughput no no
DBR1_HUMAN [view interactions] High throughput no no
EGR1_HUMAN [view interactions] High throughput no yes
DAZP1_HUMAN [view interactions] High throughput no yes
SMRC1_HUMAN [view interactions] High throughput no yes
EZHIP_HUMAN [view interactions] High throughput no no
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
CTBP2_HUMAN [view interactions] High throughput no no
SMRD2_HUMAN [view interactions] High throughput no no
CSTF3_HUMAN [view interactions] High throughput no yes
PGH2_HUMAN [view interactions] High throughput no no
CPSF7_HUMAN [view interactions] High throughput no yes
RFX1_HUMAN [view interactions] High throughput no yes
CPSF6_HUMAN [view interactions] High throughput no yes
ZN316_HUMAN [view interactions] High throughput no no
ZN451_HUMAN [view entry] [view interactions] High throughput yes no
ACTC_HUMAN [view interactions] High throughput no no
CLOCK_HUMAN [view interactions] High throughput no yes
DNJB6_HUMAN [view entry] [view interactions] High throughput yes yes
NAA40_HUMAN [view interactions] High throughput no no
M3K13_HUMAN [view interactions] High throughput no yes
CDK19_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
KS6A5_HUMAN [view entry] [view interactions] High throughput yes yes
CD2B2_HUMAN [view interactions] High throughput no yes
CATL1_HUMAN [view interactions] High throughput no yes
STK16_HUMAN [view interactions] High throughput no no
CCNC_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
PK3CB_HUMAN [view interactions] High throughput no yes
SGF29_HUMAN [view interactions] High throughput no yes
TEC_HUMAN [view interactions] High throughput no yes
FUBP2_HUMAN [view interactions] High throughput no yes
PRPK_HUMAN [view interactions] High throughput no yes
CARM1_HUMAN [view interactions] High throughput no yes
NMDE2_HUMAN [view entry] [view interactions] High throughput yes no
CABIN_HUMAN [view interactions] High throughput no yes
EIF1B_HUMAN [view interactions] High throughput no no
CR025_HUMAN [view interactions] High throughput no yes
BHE40_HUMAN [view interactions] High throughput no yes
CHK2_HUMAN [view interactions] High throughput no yes
ATF1_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
EWS_HUMAN [view interactions] High throughput no yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
INT13_HUMAN [view interactions] High throughput no no
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
API5_HUMAN [view interactions] High throughput no no
HERC2_HUMAN [view interactions] High throughput no yes
ANXA7_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
ANX11_HUMAN [view entry] [view interactions] High throughput yes yes
MYOME_HUMAN [view interactions] High throughput no no
AN32B_HUMAN [view interactions] High throughput no yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
AKP8L_HUMAN [view interactions] High throughput no yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
EP400_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
SCC4_HUMAN [view interactions] High throughput no no
RAD52_HUMAN [view interactions] High throughput no no
XRCC6_HUMAN [view interactions] High throughput no yes
BUB3_HUMAN [view interactions] High throughput no yes
NONO_HUMAN [view interactions] High throughput no yes
PSDE_HUMAN [view entry] [view interactions] High throughput yes yes
UBR5_HUMAN [view interactions] High throughput no no
PIAS3_HUMAN [view interactions] High throughput no yes
UBP3_HUMAN [view interactions] High throughput no no
HMBX1_HUMAN [view interactions] High throughput no yes
TF2H4_HUMAN [view interactions] High throughput no no
UBP34_HUMAN [view interactions] High throughput no yes
SFPQ_HUMAN [view entry] [view interactions] High throughput yes yes
NSE3_HUMAN [view interactions] High throughput no no
ZN827_HUMAN [view interactions] High throughput no yes
TOP1_HUMAN [view interactions] High throughput no yes
TLK1_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
VAC14_HUMAN [view entry] [view interactions] High throughput yes yes
CC120_HUMAN [view interactions] High throughput no no
PIAS1_HUMAN [view interactions] High throughput no yes
OXER1_HUMAN [view interactions] High throughput no yes
HNRL1_HUMAN [view interactions] High throughput no yes
PITX1_HUMAN [view interactions] High throughput no yes
ERCC1_HUMAN [view interactions] High throughput no yes
CJ055_HUMAN [view interactions] High throughput no no
ROA2_HUMAN [view entry] [view interactions] High throughput yes yes
BCL6_HUMAN [view interactions] High throughput no no
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
HGS_HUMAN [view entry] [view interactions] High throughput yes yes
RN169_HUMAN [view interactions] High throughput no no
PO6F2_HUMAN [view interactions] High throughput no no
RHNO1_HUMAN [view interactions] High throughput no no
KLD7B_HUMAN [view interactions] High throughput no no
RECQ5_HUMAN [view interactions] High throughput no no
UBAP2_HUMAN [view interactions] High throughput no yes
EMSY_HUMAN [view interactions] High throughput no yes
TLX3_HUMAN [view interactions] High throughput no no
NSE4A_HUMAN [view interactions] High throughput no yes
AT1A3_HUMAN [view entry] [view interactions] High throughput yes no
MAT1_HUMAN [view interactions] High throughput no yes
CASP6_HUMAN [view interactions] High throughput no no
UBE2K_HUMAN [view interactions] High throughput no yes
SMN_HUMAN [view interactions] High throughput no yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
TYY1_HUMAN [view interactions] High throughput no yes
PECA1_HUMAN [view interactions] High throughput no no
JHD2C_HUMAN [view interactions] High throughput no yes
PLD1_HUMAN [view interactions] High throughput no no
MUS81_HUMAN [view interactions] High throughput no no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
SMC5_HUMAN [view interactions] High throughput no yes
VIME_HUMAN [view entry] [view interactions] High throughput yes no
CBP_HUMAN [view interactions] High throughput no yes
IDLC_HUMAN [view interactions] High throughput no no
ATF3_HUMAN [view interactions] High throughput no yes
KLF11_HUMAN [view interactions] High throughput no no
CTC1_HUMAN [view interactions] High throughput no no
SPRE1_HUMAN [view interactions] High throughput no yes
ERCC3_HUMAN [view interactions] High throughput no yes
FOXK2_HUMAN [view interactions] High throughput no yes
NSE1_HUMAN [view interactions] High throughput no yes
FOXK1_HUMAN [view interactions] High throughput no yes
WRIP1_HUMAN [view interactions] High throughput no yes
PR38A_HUMAN [view interactions] High throughput no no
BARD1_HUMAN [view interactions] High throughput no yes
H1T_HUMAN [view interactions] High throughput no no
ACD_HUMAN [view interactions] High throughput no no
PHF6_HUMAN [view interactions] High throughput no yes
RECQ1_HUMAN [view interactions] High throughput no yes
AMRP_HUMAN [view interactions] High throughput no yes
TMA16_HUMAN [view interactions] High throughput no yes
ATRIP_HUMAN [view interactions] High throughput no yes
SPR2E_HUMAN [view interactions] High throughput no no
TF2H1_HUMAN [view interactions] High throughput no yes
BCKD_HUMAN [view entry] [view interactions] High throughput yes yes
ZN207_HUMAN [view interactions] High throughput no yes
TRMB_HUMAN [view interactions] High throughput no yes
XPF_HUMAN [view interactions] High throughput no yes
PI42A_HUMAN [view entry] [view interactions] High throughput yes yes
SLX4_HUMAN [view interactions] High throughput no yes
KC1E_HUMAN [view entry] [view interactions] High throughput yes yes
SETX_HUMAN [view interactions] High throughput no yes
RS21_HUMAN [view entry] [view interactions] High throughput yes yes
SLIT2_HUMAN [view interactions] High throughput no no
TINF2_HUMAN [view interactions] High throughput no no
STN1_HUMAN [view interactions] High throughput no no
POMT1_HUMAN [view interactions] High throughput no no
RAD1_HUMAN [view interactions] High throughput no yes
MRE11_HUMAN [view interactions] High throughput no yes
SMUF2_HUMAN [view interactions] High throughput no yes
RAD9A_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
ZEB1_HUMAN [view interactions] High throughput no yes
AKIP_HUMAN [view interactions] High throughput no yes
CDN1A_HUMAN [view interactions] High throughput no no
CDK8_HUMAN [view interactions] High throughput no no
BABA2_HUMAN [view interactions] High throughput no yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
BABA1_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
ATR_HUMAN [view interactions] High throughput no no
PLRKT_HUMAN [view interactions] High throughput no yes
TF2H3_HUMAN [view interactions] High throughput no yes
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
SNRPA_HUMAN [view interactions] High throughput no yes
BRCC3_HUMAN [view interactions] High throughput no no
ETV6_HUMAN [view interactions] High throughput no no
HUS1_HUMAN [view interactions] High throughput no yes
DGCR8_HUMAN [view entry] [view interactions] High throughput yes yes
ABRX1_HUMAN [view interactions] High throughput no no
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
CIRBP_HUMAN [view interactions] High throughput no no
MEF2A_HUMAN [view interactions] High throughput no yes
PSPC1_HUMAN [view interactions] High throughput no yes
ARI1B_HUMAN [view interactions] High throughput no yes
DNLI4_HUMAN [view interactions] High throughput no yes
ARI1A_HUMAN [view interactions] High throughput no yes
ACRO_HUMAN [view interactions] High throughput no no
PCNT_HUMAN [view interactions] High throughput no yes
FBH1_HUMAN [view interactions] Computational no no
H2B2E_HUMAN [view interactions] Computational no yes
PRKDC_HUMAN [view entry] [view interactions] Computational yes yes
RS27A_HUMAN [view entry] [view interactions] Computational yes yes
NHEJ1_HUMAN [view interactions] Computational no yes
TCHP_HUMAN [view interactions] Computational no yes
DPOLA_HUMAN [view interactions] Computational no yes
BRE1A_HUMAN [view interactions] Computational no yes
CTIP_HUMAN [view interactions] Computational no no
SLF1_HUMAN [view interactions] Computational no no
TIM_HUMAN [view interactions] Computational no yes
KAT5_HUMAN [view interactions] Computational no yes
ATD2B_HUMAN [view interactions] Computational no yes
RECQ4_HUMAN [view interactions] Computational no yes
PCNA_HUMAN [view interactions] Computational no no
H32_HUMAN [view interactions] Computational no yes
DPOD1_HUMAN [view interactions] Computational no yes
SIR1_HUMAN [view interactions] Computational no yes
EXO1_HUMAN [view interactions] Computational no no
BRE1B_HUMAN [view interactions] Computational no yes
NSD2_HUMAN [view interactions] Computational no yes
PWP3A_HUMAN [view interactions] Computational no yes
UB2V2_HUMAN [view entry] [view interactions] Computational yes no
XPA_HUMAN [view interactions] Computational no yes
NTH_HUMAN [view interactions] Computational no yes
DCR1C_HUMAN [view interactions] Computational no no
ATAD2_HUMAN [view interactions] Computational no no
DNA2_HUMAN [view interactions] Computational no yes
SMC1A_HUMAN [view interactions] Computational no yes
SMC3_HUMAN [view entry] [view interactions] Computational yes yes
UBE2N_HUMAN [view entry] [view interactions] Computational yes yes
FEN1_HUMAN [view interactions] Computational no yes
CTBP1_HUMAN [view entry] [view interactions] Computational yes yes
WRN_HUMAN [view interactions] Computational no yes
XRCC4_HUMAN [view interactions] Computational no yes
FANCM_HUMAN [view interactions] Computational no no
AIM2_HUMAN [view interactions] Computational no no
H37_HUMAN [view interactions] Computational no no
RAD17_HUMAN [view interactions] Computational no yes