Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

PUR6_HUMAN

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in PUR6_HUMAN
GO:0046872 metal ion binding 28.8136 4 no
GO:0017076 purine nucleotide binding 27.1186 4 yes
GO:0032555 purine ribonucleotide binding 27.1186 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 27.1186 4 yes
GO:0005524 ATP binding 22.0339 5 yes
GO:0030554 adenyl nucleotide binding 22.0339 5 yes
GO:0032559 adenyl ribonucleotide binding 22.0339 5 yes
GO:0003723 RNA binding 20.3390 4 no
GO:0045296 cadherin binding 16.9492 4 yes
GO:0004638 phosphoribosylaminoimidazole carboxylase activity 3.3898 5 yes
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 3.3898 5 yes
GO:0016831 carboxy-lyase activity 3.3898 4 yes
GO:0016881 acid-amino acid ligase activity 3.3898 4 yes
GO:0043727 5-amino-4-imidazole carboxylate lyase activity 3.3898 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in PUR6_HUMAN
GO:0060255 regulation of macromolecule metabolic process 57.6271 4 no
GO:0051171 regulation of nitrogen compound metabolic process 55.9322 4 no
GO:0080090 regulation of primary metabolic process 55.9322 4 no
GO:0031323 regulation of cellular metabolic process 54.2373 4 no
GO:0048522 positive regulation of cellular process 54.2373 4 no
GO:0048523 negative regulation of cellular process 54.2373 4 no
GO:0009893 positive regulation of metabolic process 47.4576 4 no
GO:0010604 positive regulation of macromolecule metabolic process 45.7627 5 no
GO:0051246 regulation of protein metabolic process 44.0678 5 no
GO:0051173 positive regulation of nitrogen compound metabolic process 42.3729 5 no
GO:0010646 regulation of cell communication 40.6780 4 no
GO:0010468 regulation of gene expression 40.6780 5 no
GO:0031325 positive regulation of cellular metabolic process 38.9831 5 no
GO:0006996 organelle organization 35.5932 4 no
GO:0009966 regulation of signal transduction 35.5932 4 no
GO:0009892 negative regulation of metabolic process 35.5932 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 33.8983 5 no
GO:0031399 regulation of protein modification process 33.8983 6 no
GO:0051128 regulation of cellular component organization 33.8983 4 no
GO:0009889 regulation of biosynthetic process 33.8983 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.8983 5 no
GO:0031326 regulation of cellular biosynthetic process 33.8983 5 no
GO:0022607 cellular component assembly 32.2034 4 no
GO:0019220 regulation of phosphate metabolic process 32.2034 6 no
GO:0051174 regulation of phosphorus metabolic process 32.2034 5 no
GO:0010556 regulation of macromolecule biosynthetic process 32.2034 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 32.2034 5 no
GO:0031324 negative regulation of cellular metabolic process 32.2034 5 no
GO:0008104 protein localization 30.5085 4 no
GO:0051247 positive regulation of protein metabolic process 30.5085 6 no
GO:0051252 regulation of RNA metabolic process 28.8136 5 no
GO:0048585 negative regulation of response to stimulus 28.8136 4 no
GO:1902531 regulation of intracellular signal transduction 27.1186 5 no
GO:0043412 macromolecule modification 27.1186 4 no
GO:0043933 protein-containing complex organization 27.1186 4 no
GO:0001932 regulation of protein phosphorylation 27.1186 7 no
GO:0010648 negative regulation of cell communication 27.1186 5 no
GO:0023057 negative regulation of signaling 27.1186 4 no
GO:0031401 positive regulation of protein modification process 27.1186 7 no
GO:0042325 regulation of phosphorylation 27.1186 7 no
GO:0048584 positive regulation of response to stimulus 25.4237 4 no
GO:0051248 negative regulation of protein metabolic process 25.4237 6 no
GO:0006355 regulation of DNA-templated transcription 25.4237 6 no
GO:0010941 regulation of cell death 25.4237 4 no
GO:1903506 regulation of nucleic acid-templated transcription 25.4237 7 no
GO:2001141 regulation of RNA biosynthetic process 25.4237 6 no
GO:0051049 regulation of transport 25.4237 4 no
GO:0006796 phosphate-containing compound metabolic process 25.4237 4 yes
GO:0036211 protein modification process 25.4237 4 no
GO:0009894 regulation of catabolic process 25.4237 4 no
GO:0010628 positive regulation of gene expression 25.4237 6 no
GO:0009968 negative regulation of signal transduction 23.7288 5 no
GO:0080134 regulation of response to stress 22.0339 4 no
GO:0042981 regulation of apoptotic process 22.0339 6 no
GO:0043067 regulation of programmed cell death 22.0339 5 no
GO:0051338 regulation of transferase activity 22.0339 4 no
GO:0071702 organic substance transport 22.0339 4 no
GO:0071705 nitrogen compound transport 22.0339 4 no
GO:0065003 protein-containing complex assembly 22.0339 5 no
GO:0010562 positive regulation of phosphorus metabolic process 22.0339 6 no
GO:0045937 positive regulation of phosphate metabolic process 22.0339 7 no
GO:0031329 regulation of cellular catabolic process 20.3390 5 no
GO:0080135 regulation of cellular response to stress 20.3390 4 no
GO:0043085 positive regulation of catalytic activity 20.3390 4 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.3390 6 no
GO:0071310 cellular response to organic substance 20.3390 4 no
GO:0001934 positive regulation of protein phosphorylation 20.3390 8 no
GO:0042327 positive regulation of phosphorylation 20.3390 8 no
GO:0009891 positive regulation of biosynthetic process 20.3390 5 no
GO:0031328 positive regulation of cellular biosynthetic process 20.3390 6 no
GO:1901362 organic cyclic compound biosynthetic process 18.6441 4 yes
GO:0006753 nucleoside phosphate metabolic process 16.9492 4 yes
GO:0009117 nucleotide metabolic process 16.9492 5 yes
GO:0018130 heterocycle biosynthetic process 16.9492 4 yes
GO:0044271 cellular nitrogen compound biosynthetic process 16.9492 4 yes
GO:0072521 purine-containing compound metabolic process 16.9492 4 yes
GO:0006163 purine nucleotide metabolic process 15.2542 5 yes
GO:0019438 aromatic compound biosynthetic process 15.2542 4 yes
GO:0019693 ribose phosphate metabolic process 15.2542 4 yes
GO:1901566 organonitrogen compound biosynthetic process 15.2542 4 yes
GO:0009150 purine ribonucleotide metabolic process 13.5593 6 yes
GO:0009259 ribonucleotide metabolic process 13.5593 5 yes
GO:0034654 nucleobase-containing compound biosynthetic process 13.5593 4 yes
GO:0090407 organophosphate biosynthetic process 13.5593 4 yes
GO:0072522 purine-containing compound biosynthetic process 11.8644 5 yes
GO:0006164 purine nucleotide biosynthetic process 10.1695 6 yes
GO:0009165 nucleotide biosynthetic process 10.1695 6 yes
GO:0046390 ribose phosphate biosynthetic process 10.1695 5 yes
GO:1901137 carbohydrate derivative biosynthetic process 10.1695 4 yes
GO:1901293 nucleoside phosphate biosynthetic process 10.1695 5 yes
GO:0009152 purine ribonucleotide biosynthetic process 8.4746 7 yes
GO:0009260 ribonucleotide biosynthetic process 8.4746 6 yes
GO:0006144 purine nucleobase metabolic process 5.0847 5 yes
GO:0006167 AMP biosynthetic process 5.0847 8 yes
GO:0006177 GMP biosynthetic process 5.0847 8 yes
GO:0006188 IMP biosynthetic process 5.0847 8 yes
GO:0006189 de novo IMP biosynthetic process 5.0847 9 yes
GO:0009112 nucleobase metabolic process 5.0847 4 yes
GO:0009113 purine nucleobase biosynthetic process 5.0847 6 yes
GO:0009123 nucleoside monophosphate metabolic process 5.0847 5 yes
GO:0009124 nucleoside monophosphate biosynthetic process 5.0847 6 yes
GO:0009126 purine nucleoside monophosphate metabolic process 5.0847 6 yes
GO:0009127 purine nucleoside monophosphate biosynthetic process 5.0847 7 yes
GO:0009156 ribonucleoside monophosphate biosynthetic process 5.0847 7 yes
GO:0009161 ribonucleoside monophosphate metabolic process 5.0847 6 yes
GO:0009167 purine ribonucleoside monophosphate metabolic process 5.0847 7 yes
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 5.0847 8 yes
GO:0044208 de novo AMP biosynthetic process 5.0847 9 yes
GO:0046033 AMP metabolic process 5.0847 7 yes
GO:0046037 GMP metabolic process 5.0847 7 yes
GO:0046040 IMP metabolic process 5.0847 7 yes
GO:0046112 nucleobase biosynthetic process 5.0847 5 yes
GO:0097292 XMP metabolic process 5.0847 7 yes
GO:0097293 XMP biosynthetic process 5.0847 8 yes
GO:0097294 de novo XMP biosynthetic process 5.0847 9 yes

Disease

Term Name % Distance from top the of the tree Annotated in PUR6_HUMAN
DOID:574 peripheral nervous system disease 5.0847 3 no
DOID:870 neuropathy 5.0847 4 no
DOID:1289 neurodegenerative disease 5.0847 4 no
DOID:331 central nervous system disease 5.0847 3 no
DOID:440 neuromuscular disease 3.3898 5 no
DOID:0050700 cardiomyopathy 3.3898 4 no
DOID:0060036 intrinsic cardiomyopathy 3.3898 5 no
DOID:114 heart disease 3.3898 3 no
DOID:2843 long QT syndrome 3.3898 6 no
DOID:231 motor neuron disease 3.3898 5 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PUR6_HUMAN [view entry] [view interactions] Low throughput yes yes
UB2R1_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
GLP1R_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
FAF1_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
ATX1_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
PPAC_HUMAN [view entry] [view interactions] High throughput yes yes
EYA4_HUMAN [view interactions] High throughput no yes
MGDP1_HUMAN [view interactions] High throughput no yes
MTMRE_HUMAN [view entry] [view interactions] High throughput yes yes
PHP14_HUMAN [view interactions] High throughput no yes
TP4A1_HUMAN [view interactions] High throughput no no
TP4A2_HUMAN [view interactions] High throughput no yes
PTN12_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
RGS14_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA4_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
EMC2_HUMAN [view interactions] High throughput no yes
SAMH1_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
DOCK8_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
BRD4_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
RBM39_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
ANDR_HUMAN [view interactions] High throughput no no
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
PAGE4_HUMAN [view interactions] High throughput no no
ARHGA_HUMAN [view interactions] High throughput no yes
FGD5_HUMAN [view interactions] High throughput no yes
BAG1_HUMAN [view interactions] High throughput no yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
ARP2_HUMAN [view entry] [view interactions] High throughput yes yes
AP2S1_HUMAN [view entry] [view interactions] High throughput yes no
CNBP_HUMAN [view interactions] High throughput no no
DNJC2_HUMAN [view interactions] High throughput no yes
SAR1B_HUMAN [view interactions] High throughput no yes
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
FITM2_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RIT1_HUMAN [view interactions] High throughput no yes
UBE3A_HUMAN [view interactions] High throughput no yes
PUR2_HUMAN [view interactions] High throughput no yes
ZPR1_HUMAN [view interactions] High throughput no yes
TTC1_HUMAN [view interactions] High throughput no yes
UNK_HUMAN [view interactions] High throughput no yes
PUM1_HUMAN [view interactions] High throughput no yes
SLD5_HUMAN [view interactions] High throughput no yes
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
UBE2B_HUMAN [view interactions] High throughput no no
RPAP1_HUMAN [view interactions] High throughput no yes
ZNRD2_HUMAN [view interactions] High throughput no yes
TACC3_HUMAN [view entry] [view interactions] High throughput yes yes
TM177_HUMAN [view interactions] High throughput no no
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
SYFB_HUMAN [view entry] [view interactions] High throughput yes yes
GLU2B_HUMAN [view interactions] High throughput no yes
SET_HUMAN [view interactions] High throughput no yes
QRIC1_HUMAN [view interactions] High throughput no yes
SPT5H_HUMAN [view interactions] High throughput no yes
SWP70_HUMAN [view interactions] High throughput no no
MRP1_HUMAN [view interactions] High throughput no no
ASNS_HUMAN [view interactions] High throughput no yes
ASSY_HUMAN [view interactions] High throughput no yes
PUR9_HUMAN [view entry] [view interactions] High throughput yes yes
ETFA_HUMAN [view interactions] High throughput no yes
GLOD4_HUMAN [view entry] [view interactions] High throughput yes yes
GLRX5_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
CH10_HUMAN [view interactions] High throughput no yes
IMPA2_HUMAN [view interactions] High throughput no no
MIF_HUMAN [view entry] [view interactions] High throughput yes yes
PUR8_HUMAN [view interactions] High throughput no yes
ARF1_HUMAN [view entry] [view interactions] High throughput yes yes
DAZP1_HUMAN [view interactions] High throughput no yes
UFM1_HUMAN [view interactions] High throughput no yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
PUR4_HUMAN [view interactions] High throughput no yes
KPYR_HUMAN [view entry] [view interactions] High throughput yes no
KPYM_HUMAN [view interactions] High throughput no yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
RPIA_HUMAN [view interactions] High throughput no yes
GLYC_HUMAN [view interactions] High throughput no no
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
UGPA_HUMAN [view entry] [view interactions] High throughput yes no
COBA1_HUMAN [view interactions] High throughput no no
CO6A1_HUMAN [view interactions] High throughput no no
CLPP_HUMAN [view interactions] High throughput no yes
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
MAOM_HUMAN [view interactions] High throughput no yes
PRDX4_HUMAN [view interactions] High throughput no yes
P5CR1_HUMAN [view entry] [view interactions] High throughput yes yes
P5CR2_HUMAN [view interactions] High throughput no yes
GTR3_HUMAN [view interactions] High throughput no yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
PRPS2_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
C1TC_HUMAN [view entry] [view interactions] High throughput yes no
PSMD4_HUMAN [view interactions] High throughput no yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
AGR2_HUMAN [view interactions] High throughput no no
ACTC_HUMAN [view interactions] High throughput no no
GBF1_HUMAN [view interactions] High throughput no yes
RN183_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
NBR1_HUMAN [view interactions] High throughput no yes
CACO2_HUMAN [view interactions] High throughput no yes
SQSTM_HUMAN [view interactions] High throughput no yes
PER2_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
MK13_HUMAN [view interactions] High throughput no yes
MLP3B_HUMAN [view interactions] High throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL1_HUMAN [view interactions] High throughput no yes
FTM_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
RA1L2_HUMAN [view interactions] High throughput no no
MTA1_HUMAN [view interactions] High throughput no yes
RPB7_HUMAN [view interactions] High throughput no yes
PRPF3_HUMAN [view interactions] High throughput no yes
WRP73_HUMAN [view interactions] High throughput no no
NUDC1_HUMAN [view interactions] High throughput no no
FL2D_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
SH3G3_HUMAN [view entry] [view interactions] High throughput yes no
SHC1_HUMAN [view entry] [view interactions] High throughput yes yes
RIN3_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
FINC_HUMAN [view interactions] High throughput no yes
DLDH_HUMAN [view entry] [view interactions] High throughput yes yes
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
NCF1_HUMAN [view interactions] High throughput no no
LRP4_HUMAN [view entry] [view interactions] High throughput yes yes
M3K7_HUMAN [view interactions] High throughput no yes
MP2K2_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK4_HUMAN [view interactions] High throughput no no
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
MYLK_HUMAN [view interactions] High throughput no no
MYLK4_HUMAN [view interactions] High throughput no no
NEK7_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
IF6_HUMAN [view interactions] High throughput no yes
CRCM_HUMAN [view interactions] High throughput no no
DGKE_HUMAN [view interactions] High throughput no yes
CCNA1_HUMAN [view interactions] High throughput no no
EIF1B_HUMAN [view interactions] High throughput no no
TRM7_HUMAN [view interactions] High throughput no yes
EPB41_HUMAN [view entry] [view interactions] High throughput yes no
SGK1_HUMAN [view interactions] High throughput no yes
HLAB_HUMAN [view interactions] High throughput no yes
TIMP2_HUMAN [view interactions] High throughput no no
PRS6B_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
PKHA7_HUMAN [view interactions] High throughput no yes
NIF3L_HUMAN [view interactions] High throughput no yes
NUD18_HUMAN [view interactions] High throughput no no
FXR2_HUMAN [view entry] [view interactions] High throughput yes yes
AAKG1_HUMAN [view interactions] High throughput no no
SMRD1_HUMAN [view interactions] High throughput no yes
LMBL2_HUMAN [view interactions] High throughput no no
LNX1_HUMAN [view interactions] High throughput no yes
ZMYM2_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
ARIP4_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
PHOCN_HUMAN [view interactions] High throughput no yes
CEP76_HUMAN [view interactions] High throughput no yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
CHK2_HUMAN [view interactions] High throughput no yes
TERF1_HUMAN [view interactions] High throughput no no
H2B1C_HUMAN [view interactions] High throughput no yes
MED4_HUMAN [view interactions] High throughput no yes
PIAS2_HUMAN [view interactions] High throughput no yes
PILRA_HUMAN [view interactions] High throughput no yes
UBC9_HUMAN [view interactions] High throughput no yes
SIR7_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
TP53B_HUMAN [view entry] [view interactions] High throughput yes yes
FOXP3_HUMAN [view interactions] High throughput no no
WWOX_HUMAN [view interactions] High throughput no yes
HUWE1_HUMAN [view interactions] High throughput no yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
EED_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
CRY1_HUMAN [view interactions] High throughput no yes
CRY2_HUMAN [view interactions] High throughput no yes
MCM2_HUMAN [view interactions] High throughput no no
HCD2_HUMAN [view entry] [view interactions] High throughput yes yes
U2AF2_HUMAN [view interactions] High throughput no yes
CDC73_HUMAN [view interactions] High throughput no yes
WDTC1_HUMAN [view interactions] High throughput no yes
RPTOR_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
BRCA1_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
HUTU_HUMAN [view interactions] Computational no no
GUAA_HUMAN [view interactions] Computational no no
CHD7_HUMAN [view interactions] Computational no no
NIT1_HUMAN [view interactions] Computational no yes
GLYM_HUMAN [view entry] [view interactions] Computational yes yes
LEG4_HUMAN [view interactions] Computational no no
FHIT_HUMAN [view interactions] Computational no yes
PUR1_HUMAN [view interactions] Computational no yes