SRC8_HUMAN
Contributes to the organization of the actin cytoskeleton and cell shape (PubMed). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones . Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density . Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed). Plays a role in focal adhesion assembly and turnover . In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed). Plays a role in receptor-mediated endocytosis via clathrin-coated pits . Required for stabilization of KCNH1 channels at the cell membrane (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI003882 | LIG_SH2_NCK_1 | LIG | 421 | 425 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SRC8_HUMAN |
---|---|---|---|---|
GO:0003779 | actin binding | 33.3333 | 4 | yes |
GO:0019900 | kinase binding | 25.0000 | 4 | no |
GO:0045296 | cadherin binding | 23.8889 | 4 | yes |
GO:0019901 | protein kinase binding | 23.8889 | 5 | no |
GO:0017076 | purine nucleotide binding | 23.8889 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 23.8889 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 23.8889 | 4 | no |
GO:0005524 | ATP binding | 20.5556 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 20.5556 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 20.5556 | 5 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SRC8_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 60.5556 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 50.0000 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 45.5556 | 4 | no |
GO:0010646 | regulation of cell communication | 43.8889 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 43.8889 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 42.7778 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 42.7778 | 4 | no |
GO:0006996 | organelle organization | 41.6667 | 4 | yes |
GO:0022607 | cellular component assembly | 41.1111 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 38.8889 | 4 | no |
GO:0009966 | regulation of signal transduction | 37.7778 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 37.2222 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 35.0000 | 5 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 35.0000 | 5 | no |
GO:0033043 | regulation of organelle organization | 33.3333 | 5 | yes |
GO:0010468 | regulation of gene expression | 32.7778 | 5 | no |
GO:0008104 | protein localization | 31.6667 | 4 | yes |
GO:0044087 | regulation of cellular component biogenesis | 30.0000 | 4 | yes |
GO:0051049 | regulation of transport | 29.4444 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 29.4444 | 5 | no |
GO:0007010 | cytoskeleton organization | 27.2222 | 5 | yes |
GO:0030030 | cell projection organization | 26.6667 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 26.6667 | 5 | yes |
GO:0051247 | positive regulation of protein metabolic process | 26.6667 | 6 | no |
GO:0097435 | supramolecular fiber organization | 26.1111 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 26.1111 | 5 | no |
GO:0051493 | regulation of cytoskeleton organization | 25.5556 | 6 | yes |
GO:0009892 | negative regulation of metabolic process | 25.5556 | 4 | no |
GO:0043412 | macromolecule modification | 25.5556 | 4 | no |
GO:0036211 | protein modification process | 25.0000 | 4 | no |
GO:0010941 | regulation of cell death | 24.4444 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 24.4444 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 24.4444 | 5 | no |
GO:0031344 | regulation of cell projection organization | 24.4444 | 5 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 24.4444 | 6 | no |
GO:0007015 | actin filament organization | 23.8889 | 5 | yes |
GO:0031399 | regulation of protein modification process | 23.8889 | 6 | no |
GO:0048584 | positive regulation of response to stimulus | 23.8889 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 23.3333 | 5 | no |
GO:0045595 | regulation of cell differentiation | 23.3333 | 4 | no |
GO:0010647 | positive regulation of cell communication | 23.3333 | 5 | no |
GO:0023056 | positive regulation of signaling | 23.3333 | 4 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 22.7778 | 5 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 22.7778 | 5 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.7778 | 5 | no |
GO:0071310 | cellular response to organic substance | 22.7778 | 4 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 22.7778 | 4 | no |
GO:0042981 | regulation of apoptotic process | 22.2222 | 6 | yes |
GO:0043067 | regulation of programmed cell death | 22.2222 | 5 | yes |
GO:0019220 | regulation of phosphate metabolic process | 22.2222 | 6 | no |
GO:0051174 | regulation of phosphorus metabolic process | 22.2222 | 5 | no |
GO:0043933 | protein-containing complex organization | 21.6667 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 21.6667 | 5 | no |
GO:0051129 | negative regulation of cellular component organization | 21.6667 | 5 | no |
GO:0060341 | regulation of cellular localization | 21.6667 | 4 | no |
GO:0016192 | vesicle-mediated transport | 21.1111 | 4 | yes |
GO:0032970 | regulation of actin filament-based process | 21.1111 | 4 | yes |
GO:1902903 | regulation of supramolecular fiber organization | 21.1111 | 5 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.1111 | 5 | no |
GO:0032956 | regulation of actin cytoskeleton organization | 20.5556 | 5 | yes |
GO:0043085 | positive regulation of catalytic activity | 20.5556 | 4 | no |
GO:0051094 | positive regulation of developmental process | 20.5556 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 19.4444 | 4 | yes |
GO:0110053 | regulation of actin filament organization | 19.4444 | 6 | yes |
GO:0010648 | negative regulation of cell communication | 18.3333 | 5 | yes |
GO:0023057 | negative regulation of signaling | 18.3333 | 4 | yes |
GO:0034330 | cell junction organization | 18.3333 | 4 | yes |
GO:0009894 | regulation of catabolic process | 17.7778 | 4 | yes |
GO:0009968 | negative regulation of signal transduction | 17.2222 | 5 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 17.2222 | 5 | yes |
GO:0065003 | protein-containing complex assembly | 17.2222 | 5 | yes |
GO:0071702 | organic substance transport | 17.2222 | 4 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 16.6667 | 4 | yes |
GO:0071705 | nitrogen compound transport | 15.5556 | 4 | yes |
GO:0032535 | regulation of cellular component size | 15.0000 | 4 | yes |
GO:0034329 | cell junction assembly | 15.0000 | 5 | yes |
GO:0010638 | positive regulation of organelle organization | 14.4444 | 6 | yes |
GO:0032271 | regulation of protein polymerization | 14.4444 | 6 | yes |
GO:0060548 | negative regulation of cell death | 14.4444 | 5 | yes |
GO:0015031 | protein transport | 13.8889 | 4 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 13.8889 | 5 | yes |
GO:0043066 | negative regulation of apoptotic process | 13.3333 | 7 | yes |
GO:0043069 | negative regulation of programmed cell death | 13.3333 | 6 | yes |
GO:0008064 | regulation of actin polymerization or depolymerization | 12.7778 | 6 | yes |
GO:0030832 | regulation of actin filament length | 12.7778 | 5 | yes |
GO:0031329 | regulation of cellular catabolic process | 12.7778 | 5 | yes |
GO:0032990 | cell part morphogenesis | 12.2222 | 4 | yes |
GO:0006897 | endocytosis | 11.6667 | 5 | yes |
GO:0030833 | regulation of actin filament polymerization | 11.6667 | 7 | yes |
GO:0048858 | cell projection morphogenesis | 11.6667 | 5 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 11.6667 | 6 | yes |
GO:0030031 | cell projection assembly | 10.5556 | 5 | yes |
GO:0044057 | regulation of system process | 10.5556 | 4 | yes |
GO:0120031 | plasma membrane bounded cell projection assembly | 10.5556 | 6 | yes |
GO:0048812 | neuron projection morphogenesis | 10.0000 | 7 | yes |
GO:0051495 | positive regulation of cytoskeleton organization | 8.8889 | 7 | yes |
GO:1902905 | positive regulation of supramolecular fiber organization | 8.8889 | 6 | yes |
GO:0006886 | intracellular protein transport | 7.7778 | 4 | yes |
GO:0008154 | actin polymerization or depolymerization | 7.7778 | 6 | yes |
GO:2001233 | regulation of apoptotic signaling pathway | 7.7778 | 5 | yes |
GO:0031334 | positive regulation of protein-containing complex assembly | 7.2222 | 6 | yes |
GO:0010506 | regulation of autophagy | 6.6667 | 6 | yes |
GO:0090257 | regulation of muscle system process | 6.6667 | 5 | yes |
GO:0001558 | regulation of cell growth | 6.1111 | 4 | yes |
GO:0006898 | receptor-mediated endocytosis | 6.1111 | 6 | yes |
GO:0097581 | lamellipodium organization | 6.1111 | 6 | yes |
GO:0031532 | actin cytoskeleton reorganization | 5.5556 | 4 | yes |
GO:0048638 | regulation of developmental growth | 5.5556 | 4 | yes |
GO:0051258 | protein polymerization | 5.5556 | 6 | yes |
GO:0106027 | neuron projection organization | 5.5556 | 6 | yes |
GO:0010821 | regulation of mitochondrion organization | 5.0000 | 6 | yes |
GO:0032273 | positive regulation of protein polymerization | 5.0000 | 7 | yes |
GO:0097061 | dendritic spine organization | 5.0000 | 5 | yes |
GO:0099173 | postsynapse organization | 5.0000 | 4 | yes |
GO:2001234 | negative regulation of apoptotic signaling pathway | 5.0000 | 6 | yes |
GO:0006937 | regulation of muscle contraction | 4.4444 | 6 | yes |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 4.4444 | 6 | yes |
GO:0030041 | actin filament polymerization | 3.8889 | 7 | yes |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 3.8889 | 7 | yes |
GO:0007044 | cell-substrate junction assembly | 3.3333 | 6 | yes |
GO:0030516 | regulation of axon extension | 3.3333 | 5 | yes |
GO:0061387 | regulation of extent of cell growth | 3.3333 | 5 | yes |
GO:0150115 | cell-substrate junction organization | 3.3333 | 5 | yes |
GO:0006940 | regulation of smooth muscle contraction | 2.7778 | 7 | yes |
GO:0030838 | positive regulation of actin filament polymerization | 2.7778 | 7 | yes |
GO:0043954 | cellular component maintenance | 2.7778 | 4 | yes |
GO:0048041 | focal adhesion assembly | 2.7778 | 7 | yes |
GO:0097062 | dendritic spine maintenance | 2.2222 | 5 | yes |
GO:0045933 | positive regulation of muscle contraction | 1.6667 | 5 | yes |
GO:0045987 | positive regulation of smooth muscle contraction | 1.6667 | 6 | yes |
GO:0006930 | substrate-dependent cell migration, cell extension | 1.1111 | 7 | yes |
GO:1903146 | regulation of autophagy of mitochondrion | 1.1111 | 7 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in SRC8_HUMAN |
---|---|---|---|---|
DOID:114 | heart disease | 2.2222 | 3 | no |
DOID:0080000 | muscular disease | 2.2222 | 3 | no |
DOID:423 | myopathy | 2.2222 | 5 | no |
DOID:66 | muscle tissue disease | 2.2222 | 4 | no |
DOID:0050700 | cardiomyopathy | 1.6667 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 1.6667 | 5 | no |
DOID:9884 | muscular dystrophy | 1.6667 | 6 | no |
DOID:2843 | long QT syndrome | 1.1111 | 6 | no |
DOID:0060038 | specific developmental disorder | 1.1111 | 3 | no |
DOID:1059 | intellectual disability | 1.1111 | 4 | no |
DOID:331 | central nervous system disease | 1.1111 | 3 | no |
DOID:0050851 | glomerulosclerosis | 1.1111 | 6 | no |
DOID:10952 | nephritis | 1.1111 | 4 | no |
DOID:1312 | focal segmental glomerulosclerosis | 1.1111 | 7 | no |
DOID:2921 | glomerulonephritis | 1.1111 | 5 | no |
DOID:557 | kidney disease | 1.1111 | 3 | no |
DOID:0110274 | autosomal recessive limb-girdle muscular dystrophy | 1.1111 | 8 | no |
DOID:11724 | limb-girdle muscular dystrophy | 1.1111 | 7 | no |
DOID:0050155 | sensory system disease | 1.1111 | 3 | no |
DOID:0050563 | nonsyndromic deafness | 1.1111 | 5 | no |
DOID:0050564 | autosomal dominant nonsyndromic deafness | 1.1111 | 6 | no |
DOID:2742 | auditory system disease | 1.1111 | 4 | no |
DOID:0050557 | congenital muscular dystrophy | 1.1111 | 7 | no |
DOID:440 | neuromuscular disease | 1.1111 | 5 | no |
DOID:574 | peripheral nervous system disease | 1.1111 | 3 | no |
DOID:65 | connective tissue disease | 1.1111 | 3 | no |
DOID:870 | neuropathy | 1.1111 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
RHG35_HUMAN | [view interactions] | Low throughput | no | yes |
FGD1_HUMAN | [view interactions] | Low throughput | no | no |
WIPF1_HUMAN | [view interactions] | Low throughput | no | no |
WASL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KCMA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
MTSS1_HUMAN | [view interactions] | Low throughput | no | no |
SRCN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HAKAI_HUMAN | [view interactions] | Low throughput | no | yes |
ARP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
COF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ARP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTND1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KCNA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HIP1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PTN1_HUMAN | [view interactions] | Low throughput | no | yes |
DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HDAC6_HUMAN | [view interactions] | Low throughput | no | yes |
ARPC3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ARPC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ARPC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WASP_HUMAN | [view interactions] | Low throughput | no | yes |
NCK1_HUMAN | [view interactions] | Low throughput | no | yes |
MMP2_HUMAN | [view interactions] | Low throughput | no | no |
ABL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CCL2_HUMAN | [view interactions] | Low throughput | no | no |
WASF2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PKD1_HUMAN | [view interactions] | Low throughput | no | yes |
UBB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SDC3_HUMAN | [view interactions] | Low throughput | no | yes |
RL40_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ACTG_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
EXOC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
WASH1_HUMAN | [view interactions] | Low throughput | no | yes |
LYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KCNA3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
PAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SPR2A_HUMAN | [view interactions] | Low throughput | no | no |
PDK2_HUMAN | [view interactions] | Low throughput | no | yes |
PAXI_HUMAN | [view interactions] | Low throughput | no | yes |
MYLK_HUMAN | [view interactions] | Low throughput | no | no |
KSYK_HUMAN | [view interactions] | Low throughput | no | no |
CASP3_HUMAN | [view interactions] | Low throughput | no | yes |
SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FER_HUMAN | [view interactions] | Low throughput | no | yes |
CRUM2_HUMAN | [view interactions] | Low throughput | no | no |
SIR1_HUMAN | [view interactions] | Low throughput | no | yes |
EP300_HUMAN | [view interactions] | Low throughput | no | yes |
MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FBW1A_HUMAN | [view interactions] | Low throughput | no | yes |
CD2AP_HUMAN | [view interactions] | Low throughput | no | no |
SPD2A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ACK1_HUMAN | [view interactions] | Low throughput | no | yes |
NCF1_HUMAN | [view interactions] | Low throughput | no | no |
TRI15_HUMAN | [view interactions] | Low throughput | no | no |
CASL_HUMAN | [view interactions] | Low throughput | no | yes |
AURKA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
YES_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KEAP1_HUMAN | [view interactions] | Low throughput | no | yes |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
ECT2_HUMAN | [view interactions] | High throughput | no | no |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRD4_HUMAN | [view interactions] | High throughput | no | yes |
CSN5_HUMAN | [view interactions] | High throughput | no | yes |
CFAD_HUMAN | [view interactions] | High throughput | no | no |
FNDC5_HUMAN | [view interactions] | High throughput | no | no |
RBM39_HUMAN | [view interactions] | High throughput | no | yes |
MT21E_HUMAN | [view interactions] | High throughput | no | no |
DDX42_HUMAN | [view interactions] | High throughput | no | yes |
PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
CPSF5_HUMAN | [view interactions] | High throughput | no | yes |
AMRP_HUMAN | [view interactions] | High throughput | no | yes |
NUFP2_HUMAN | [view interactions] | High throughput | no | no |
SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
TYY1_HUMAN | [view interactions] | High throughput | no | yes |
TOP1_HUMAN | [view interactions] | High throughput | no | yes |
RBM25_HUMAN | [view interactions] | High throughput | no | yes |
RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATX2L_HUMAN | [view interactions] | High throughput | no | no |
TOX4_HUMAN | [view interactions] | High throughput | no | yes |
IF5A1_HUMAN | [view interactions] | High throughput | no | yes |
MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
PI42A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPSF6_HUMAN | [view interactions] | High throughput | no | yes |
WDR82_HUMAN | [view interactions] | High throughput | no | no |
DHE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAF2_HUMAN | [view interactions] | High throughput | no | no |
PR40A_HUMAN | [view interactions] | High throughput | no | yes |
RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MECP2_HUMAN | [view interactions] | High throughput | no | yes |
KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MMTA2_HUMAN | [view interactions] | High throughput | no | yes |
MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TACO1_HUMAN | [view interactions] | High throughput | no | yes |
DCA13_HUMAN | [view interactions] | High throughput | no | yes |
PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
FIP1_HUMAN | [view interactions] | High throughput | no | yes |
CBX4_HUMAN | [view interactions] | High throughput | no | yes |
DDX56_HUMAN | [view interactions] | High throughput | no | yes |
PDIA6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FA76B_HUMAN | [view interactions] | High throughput | no | no |
RCL1_HUMAN | [view interactions] | High throughput | no | no |
RB15B_HUMAN | [view interactions] | High throughput | no | yes |
MET17_HUMAN | [view interactions] | High throughput | no | yes |
AMOT_HUMAN | [view interactions] | High throughput | no | no |
CCNT2_HUMAN | [view interactions] | High throughput | no | yes |
FA98A_HUMAN | [view interactions] | High throughput | no | no |
SF3B2_HUMAN | [view interactions] | High throughput | no | yes |
NUSAP_HUMAN | [view interactions] | High throughput | no | no |
PR38A_HUMAN | [view interactions] | High throughput | no | no |
LYAR_HUMAN | [view interactions] | High throughput | no | no |
ELOA1_HUMAN | [view interactions] | High throughput | no | yes |
DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
POP1_HUMAN | [view interactions] | High throughput | no | no |
RRP1B_HUMAN | [view interactions] | High throughput | no | yes |
CAH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RS21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HXA5_HUMAN | [view interactions] | High throughput | no | no |
SNIP1_HUMAN | [view interactions] | High throughput | no | no |
TMA16_HUMAN | [view interactions] | High throughput | no | yes |
RNF4_HUMAN | [view interactions] | High throughput | no | yes |
EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M4K5_HUMAN | [view interactions] | High throughput | no | no |
ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MA2C1_HUMAN | [view interactions] | High throughput | no | no |
SH24A_HUMAN | [view interactions] | High throughput | no | no |
SLX4_HUMAN | [view interactions] | High throughput | no | yes |
HEMH_HUMAN | [view interactions] | High throughput | no | yes |
ANR54_HUMAN | [view interactions] | High throughput | no | yes |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAP2_HUMAN | [view interactions] | High throughput | no | yes |
NPHP4_HUMAN | [view interactions] | High throughput | no | yes |
KS6A1_HUMAN | [view interactions] | High throughput | no | yes |
ATF2_HUMAN | [view interactions] | High throughput | no | yes |
ESR1_HUMAN | [view interactions] | High throughput | no | no |
SIR6_HUMAN | [view interactions] | High throughput | no | yes |
SIK2_HUMAN | [view interactions] | High throughput | no | yes |
CLU_HUMAN | [view interactions] | High throughput | no | yes |
LC7L2_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
ACTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGLN3_HUMAN | [view interactions] | High throughput | no | no |
CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIFC3_HUMAN | [view interactions] | High throughput | no | no |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCBP2_HUMAN | [view interactions] | High throughput | no | yes |
CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STRP1_HUMAN | [view interactions] | High throughput | no | yes |
MYO19_HUMAN | [view interactions] | High throughput | no | yes |
FOCAD_HUMAN | [view interactions] | High throughput | no | no |
FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AIF1L_HUMAN | [view interactions] | High throughput | no | yes |
ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FLNB_HUMAN | [view interactions] | High throughput | no | no |
UBN2_HUMAN | [view interactions] | High throughput | no | yes |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LUZP1_HUMAN | [view interactions] | High throughput | no | yes |
DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTC_HUMAN | [view interactions] | High throughput | no | no |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HIRA_HUMAN | [view interactions] | High throughput | no | yes |
MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TWF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STRN3_HUMAN | [view interactions] | High throughput | no | yes |
MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEXN_HUMAN | [view interactions] | High throughput | no | yes |
CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MLH1_HUMAN | [view interactions] | High throughput | no | yes |
SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPN90_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAI14_HUMAN | [view interactions] | High throughput | no | yes |
NOP9_HUMAN | [view interactions] | High throughput | no | no |
CT2NL_HUMAN | [view interactions] | High throughput | no | yes |
HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDE1_HUMAN | [view interactions] | High throughput | no | yes |
STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WRP73_HUMAN | [view interactions] | High throughput | no | no |
H2B1C_HUMAN | [view interactions] | High throughput | no | yes |
SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
LRRF2_HUMAN | [view interactions] | High throughput | no | yes |
SH3L1_HUMAN | [view interactions] | High throughput | no | yes |
CABIN_HUMAN | [view interactions] | High throughput | no | yes |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NEB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
COF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASF1A_HUMAN | [view interactions] | High throughput | no | no |
ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNO10_HUMAN | [view interactions] | High throughput | no | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H1X_HUMAN | [view interactions] | High throughput | no | yes |
K1671_HUMAN | [view interactions] | High throughput | no | yes |
ARP5L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFHD1_HUMAN | [view interactions] | High throughput | no | no |
CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TEAD1_HUMAN | [view interactions] | High throughput | no | no |
ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
CTTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SCRB2_HUMAN | [view interactions] | High throughput | no | yes |
SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VMP1_HUMAN | [view interactions] | High throughput | no | yes |
ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
CYTSA_HUMAN | [view interactions] | High throughput | no | yes |
PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAX7_HUMAN | [view interactions] | High throughput | no | no |
PKHG3_HUMAN | [view interactions] | High throughput | no | yes |
CNOT1_HUMAN | [view interactions] | High throughput | no | yes |
SNW1_HUMAN | [view interactions] | High throughput | no | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRCA2_HUMAN | [view interactions] | High throughput | no | no |
MCM7_HUMAN | [view interactions] | High throughput | no | no |
SMCA4_HUMAN | [view interactions] | High throughput | no | yes |
BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
MYPT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARC1B_HUMAN | [view interactions] | High throughput | no | no |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
LIN7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LITD1_HUMAN | [view interactions] | High throughput | no | no |
PRC1_HUMAN | [view interactions] | High throughput | no | yes |
HMGB1_HUMAN | [view interactions] | High throughput | no | yes |
ARPC5_HUMAN | [view interactions] | High throughput | no | yes |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
MTMR5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WDR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TULP3_HUMAN | [view interactions] | High throughput | no | yes |
STK26_HUMAN | [view interactions] | High throughput | no | no |
RHG17_HUMAN | [view interactions] | High throughput | no | no |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
MBP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SDHF2_HUMAN | [view interactions] | High throughput | no | yes |
SART3_HUMAN | [view interactions] | High throughput | no | yes |
THY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UPAR_HUMAN | [view interactions] | High throughput | no | yes |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCNT1_HUMAN | [view interactions] | High throughput | no | yes |
SUCB2_HUMAN | [view interactions] | High throughput | no | no |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
SCOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KDM4C_HUMAN | [view interactions] | High throughput | no | no |
COR1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NDC80_HUMAN | [view interactions] | High throughput | no | no |
ACPH_HUMAN | [view interactions] | High throughput | no | yes |
ATG7_HUMAN | [view interactions] | High throughput | no | yes |
VATC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TINF2_HUMAN | [view interactions] | High throughput | no | no |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACD_HUMAN | [view interactions] | High throughput | no | no |
GARS_HUMAN | [view interactions] | High throughput | no | yes |
IDE_HUMAN | [view interactions] | High throughput | no | yes |
MAOX_HUMAN | [view interactions] | High throughput | no | yes |
RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GLYC_HUMAN | [view interactions] | High throughput | no | no |
NECD_HUMAN | [view interactions] | High throughput | no | no |
GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LA_HUMAN | [view interactions] | High throughput | no | yes |
CHD3_HUMAN | [view interactions] | High throughput | no | yes |
STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
3BP2_HUMAN | [view interactions] | High throughput | no | yes |
VTA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERF3A_HUMAN | [view interactions] | High throughput | no | yes |
SF01_HUMAN | [view interactions] | High throughput | no | yes |
ERF3B_HUMAN | [view interactions] | High throughput | no | yes |
SFPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYSC_HUMAN | [view interactions] | High throughput | no | yes |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
SNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YTHD1_HUMAN | [view interactions] | High throughput | no | no |
SNX2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GTSE1_HUMAN | [view interactions] | High throughput | no | no |
UGDH_HUMAN | [view interactions] | High throughput | no | no |
PRP6_HUMAN | [view interactions] | High throughput | no | yes |
CSN7A_HUMAN | [view interactions] | High throughput | no | yes |
SF3B4_HUMAN | [view interactions] | High throughput | no | yes |
MYO1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM15_HUMAN | [view interactions] | High throughput | no | yes |
USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RL37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GNA13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YTHD3_HUMAN | [view interactions] | High throughput | no | no |
TPM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPSF7_HUMAN | [view interactions] | High throughput | no | yes |
URP2_HUMAN | [view interactions] | High throughput | no | no |
NONO_HUMAN | [view interactions] | High throughput | no | yes |
TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ZC11A_HUMAN | [view interactions] | High throughput | no | yes |
TXNIP_HUMAN | [view interactions] | High throughput | no | no |
ZC11B_HUMAN | [view interactions] | High throughput | no | no |
GBF1_HUMAN | [view interactions] | High throughput | no | yes |
DCA15_HUMAN | [view interactions] | High throughput | no | no |
BICD1_HUMAN | [view interactions] | High throughput | no | yes |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
RAD21_HUMAN | [view interactions] | High throughput | no | yes |
NIN_HUMAN | [view interactions] | High throughput | no | no |
RHBL4_HUMAN | [view interactions] | High throughput | no | no |
RHDF2_HUMAN | [view interactions] | High throughput | no | yes |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RN183_HUMAN | [view interactions] | High throughput | no | no |
NAA40_HUMAN | [view interactions] | High throughput | no | no |
UFO_HUMAN | [view interactions] | High throughput | no | no |
PML_HUMAN | [view interactions] | High throughput | no | yes |
NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PAN2_HUMAN | [view interactions] | High throughput | no | no |
NPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
RAD18_HUMAN | [view interactions] | High throughput | no | yes |
TES_HUMAN | [view interactions] | High throughput | no | yes |
ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AAR2_HUMAN | [view interactions] | High throughput | no | no |
PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GPC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CDK9_HUMAN | [view interactions] | High throughput | no | yes |
FAF1_HUMAN | [view interactions] | High throughput | no | yes |
ATX1_HUMAN | [view interactions] | High throughput | no | yes |
APEX1_HUMAN | [view interactions] | High throughput | no | yes |
DUS28_HUMAN | [view interactions] | High throughput | no | yes |
TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MATR3_HUMAN | [view interactions] | High throughput | no | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BIRC3_HUMAN | [view interactions] | High throughput | no | no |
WWP2_HUMAN | [view interactions] | High throughput | no | no |
RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOX2_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
PINK1_HUMAN | [view interactions] | High throughput | no | yes |
DYN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PAK4_HUMAN | [view interactions] | Computational | no | yes |
PLDX1_HUMAN | [view interactions] | Computational | no | no |
GIT2_HUMAN | [view interactions] | Computational | no | yes |
LAMC2_HUMAN | [view interactions] | Computational | no | no |
ARHG6_HUMAN | [view interactions] | Computational | no | no |
KCNA5_HUMAN | [view interactions] | Computational | no | no |
CTNB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CADH2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PTN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LAMB2_HUMAN | [view interactions] | Computational | no | yes |
ACTS_HUMAN | [view interactions] | Computational | no | no |
PAK5_HUMAN | [view interactions] | Computational | no | yes |
LAMA5_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ITA1_HUMAN | [view interactions] | Computational | no | yes |
PAK3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
UTRN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ITB1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DAG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ACM1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RHOA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AGRIN_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LAMB1_HUMAN | [view interactions] | Computational | no | yes |
CAD17_HUMAN | [view interactions] | Computational | no | no |
LAMB3_HUMAN | [view interactions] | Computational | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SHOT1_HUMAN | [view interactions] | Computational | no | no |
CXA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KPCD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LAMA3_HUMAN | [view interactions] | Computational | no | no |
ARHG7_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RAPSN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LAMC1_HUMAN | [view interactions] | Computational | no | yes |
ZO2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ACHA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
VINC_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
HOME1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
LAMA1_HUMAN | [view interactions] | Computational | no | no |
LAMC3_HUMAN | [view interactions] | Computational | no | no |
EZRI_HUMAN | [view entry] [view interactions] | Computational | yes | no |
DOCK4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
LAMA2_HUMAN | [view interactions] | Computational | no | no |
HAX1_HUMAN | [view interactions] | Computational | no | no |