CYTSB_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in CYTSB_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 37.5000 | 4 | no |
| GO:0019901 | protein kinase binding | 37.5000 | 5 | no |
| GO:0017076 | purine nucleotide binding | 34.3750 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 34.3750 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 34.3750 | 4 | no |
| GO:0003779 | actin binding | 28.1250 | 4 | no |
| GO:0046872 | metal ion binding | 20.3125 | 4 | no |
| GO:0003924 | GTPase activity | 20.3125 | 7 | no |
| GO:0005525 | GTP binding | 20.3125 | 5 | no |
| GO:0016462 | pyrophosphatase activity | 20.3125 | 5 | no |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 20.3125 | 4 | no |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 20.3125 | 6 | no |
| GO:0019001 | guanyl nucleotide binding | 20.3125 | 5 | no |
| GO:0032561 | guanyl ribonucleotide binding | 20.3125 | 5 | no |
| GO:0045296 | cadherin binding | 20.3125 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in CYTSB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 76.5625 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 62.5000 | 4 | no |
| GO:0006996 | organelle organization | 59.3750 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 54.6875 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 53.1250 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 53.1250 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 48.4375 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 46.8750 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 45.3125 | 4 | no |
| GO:0022607 | cellular component assembly | 45.3125 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.7500 | 5 | no |
| GO:0010646 | regulation of cell communication | 42.1875 | 4 | no |
| GO:0033043 | regulation of organelle organization | 40.6250 | 5 | no |
| GO:0007010 | cytoskeleton organization | 40.6250 | 5 | yes |
| GO:0008104 | protein localization | 40.6250 | 4 | no |
| GO:0010468 | regulation of gene expression | 39.0625 | 5 | no |
| GO:0051049 | regulation of transport | 39.0625 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 39.0625 | 5 | no |
| GO:0009966 | regulation of signal transduction | 37.5000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 37.5000 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 37.5000 | 5 | no |
| GO:0051493 | regulation of cytoskeleton organization | 35.9375 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 35.9375 | 4 | no |
| GO:0097435 | supramolecular fiber organization | 34.3750 | 4 | no |
| GO:0030030 | cell projection organization | 32.8125 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 32.8125 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 31.2500 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 31.2500 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 31.2500 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 31.2500 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 29.6875 | 5 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 29.6875 | 5 | no |
| GO:0031399 | regulation of protein modification process | 29.6875 | 6 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.6875 | 6 | no |
| GO:0051726 | regulation of cell cycle | 29.6875 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 29.6875 | 5 | no |
| GO:0007015 | actin filament organization | 29.6875 | 5 | no |
| GO:0030334 | regulation of cell migration | 28.1250 | 5 | no |
| GO:2000145 | regulation of cell motility | 28.1250 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 28.1250 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 28.1250 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 28.1250 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 28.1250 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 26.5625 | 7 | no |
| GO:0009889 | regulation of biosynthetic process | 26.5625 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.5625 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 26.5625 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.5625 | 5 | no |
| GO:0031401 | positive regulation of protein modification process | 26.5625 | 7 | no |
| GO:0031344 | regulation of cell projection organization | 26.5625 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 26.5625 | 6 | no |
| GO:0010941 | regulation of cell death | 25.0000 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 25.0000 | 5 | no |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 25.0000 | 4 | no |
| GO:0060341 | regulation of cellular localization | 25.0000 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 25.0000 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 25.0000 | 6 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0042327 | positive regulation of phosphorylation | 25.0000 | 8 | no |
| GO:0043085 | positive regulation of catalytic activity | 25.0000 | 4 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 25.0000 | 7 | no |
| GO:0022604 | regulation of cell morphogenesis | 23.4375 | 5 | no |
| GO:0051050 | positive regulation of transport | 23.4375 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 23.4375 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.4375 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 23.4375 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 23.4375 | 5 | no |
| GO:0071705 | nitrogen compound transport | 23.4375 | 4 | no |
| GO:0032880 | regulation of protein localization | 23.4375 | 5 | no |
| GO:0036211 | protein modification process | 23.4375 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 23.4375 | 4 | no |
| GO:0043412 | macromolecule modification | 23.4375 | 4 | no |
| GO:0051094 | positive regulation of developmental process | 23.4375 | 4 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 23.4375 | 8 | no |
| GO:0030155 | regulation of cell adhesion | 23.4375 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.4375 | 5 | no |
| GO:0061024 | membrane organization | 23.4375 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 21.8750 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 21.8750 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.8750 | 6 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 21.8750 | 5 | no |
| GO:0051338 | regulation of transferase activity | 21.8750 | 4 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 21.8750 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.8750 | 6 | no |
| GO:0071310 | cellular response to organic substance | 20.3125 | 4 | no |
| GO:0110053 | regulation of actin filament organization | 20.3125 | 6 | no |
| GO:0015031 | protein transport | 20.3125 | 4 | no |
| GO:0010564 | regulation of cell cycle process | 20.3125 | 5 | no |
| GO:0043549 | regulation of kinase activity | 20.3125 | 5 | no |
| GO:0051248 | negative regulation of protein metabolic process | 20.3125 | 6 | no |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in CYTSB_HUMAN |
|---|---|---|---|---|
| DOID:114 | heart disease | 6.2500 | 3 | no |
| DOID:0050700 | cardiomyopathy | 4.6875 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 4.6875 | 5 | no |
| DOID:2843 | long QT syndrome | 3.1250 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DAXX_HUMAN | [view interactions] | Low throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WRP73_HUMAN | [view interactions] | High throughput | no | no |
| KSR2_HUMAN | [view interactions] | High throughput | no | yes |
| S2541_HUMAN | [view interactions] | High throughput | no | no |
| PCDBB_HUMAN | [view interactions] | High throughput | no | no |
| RFIP4_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| CHK2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VMP1_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK1_HUMAN | [view interactions] | High throughput | no | no |
| POC1B_HUMAN | [view interactions] | High throughput | no | no |
| ERH_HUMAN | [view interactions] | High throughput | no | yes |
| STAG2_HUMAN | [view interactions] | High throughput | no | yes |
| SCC4_HUMAN | [view interactions] | High throughput | no | no |
| TRI69_HUMAN | [view interactions] | High throughput | no | no |
| CBX7_HUMAN | [view interactions] | High throughput | no | yes |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| CCD61_HUMAN | [view interactions] | High throughput | no | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| RING2_HUMAN | [view interactions] | High throughput | no | yes |
| RAB5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITA5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| PCGF1_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA4_HUMAN | [view interactions] | High throughput | no | no |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| PCDGD_HUMAN | [view interactions] | High throughput | no | no |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| PPIE_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| R144A_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBBP5_HUMAN | [view interactions] | High throughput | no | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| PRC1_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCDA8_HUMAN | [view interactions] | High throughput | no | no |
| K1H1_HUMAN | [view interactions] | High throughput | no | no |
| TMM74_HUMAN | [view interactions] | High throughput | no | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| KRT37_HUMAN | [view interactions] | High throughput | no | no |
| PCDGE_HUMAN | [view interactions] | High throughput | no | no |
| PCDGH_HUMAN | [view interactions] | High throughput | no | no |
| CAD23_HUMAN | [view interactions] | High throughput | no | yes |
| TM169_HUMAN | [view interactions] | High throughput | no | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOQ_HUMAN | [view interactions] | High throughput | no | no |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHOC_HUMAN | [view interactions] | High throughput | no | no |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| CALD1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2AA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| CAV1_HUMAN | [view interactions] | High throughput | no | no |
| DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| LAMP3_HUMAN | [view interactions] | High throughput | no | no |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AFAD_HUMAN | [view interactions] | High throughput | no | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| RB11A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| STX4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI36_HUMAN | [view interactions] | High throughput | no | no |
| ZFPL1_HUMAN | [view interactions] | High throughput | no | yes |
| VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NBR1_HUMAN | [view interactions] | High throughput | no | yes |
| PRS57_HUMAN | [view interactions] | Computational | no | no |
| SH2D3_HUMAN | [view interactions] | Computational | no | no |
| SH23A_HUMAN | [view interactions] | Computational | no | no |