LYN_HUMAN
Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. Functions primarily as negative regulator, but can also function as activator, depending on the context. Required for the initiation of the B-cell response, but also for its down-regulation and termination. Plays an important role in the regulation of B-cell differentiation, proliferation, survival and apoptosis, and is important for immune self-tolerance. Acts downstream of several immune receptors, including the B-cell receptor, CD79A, CD79B, CD5, CD19, CD22, FCER1, FCGR2, FCGR1A, TLR2 and TLR4. Plays a role in the inflammatory response to bacterial lipopolysaccharide. Mediates the responses to cytokines and growth factors in hematopoietic progenitors, platelets, erythrocytes, and in mature myeloid cells, such as dendritic cells, neutrophils and eosinophils. Acts downstream of EPOR, KIT, MPL, the chemokine receptor CXCR4, as well as the receptors for IL3, IL5 and CSF2. Plays an important role in integrin signaling. Regulates cell proliferation, survival, differentiation, migration, adhesion, degranulation, and cytokine release. Down-regulates signaling pathways by phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIM), that then serve as binding sites for phosphatases, such as PTPN6/SHP-1, PTPN11/SHP-2 and INPP5D/SHIP-1, that modulate signaling by dephosphorylation of kinases and their substrates. Phosphorylates LIME1 in response to CD22 activation. Phosphorylates BTK, CBL, CD5, CD19, CD72, CD79A, CD79B, CSF2RB, DOK1, HCLS1, LILRB3/PIR-B, MS4A2/FCER1B, SYK and TEC. Promotes phosphorylation of SIRPA, PTPN6/SHP-1, PTPN11/SHP-2 and INPP5D/SHIP-1. Mediates phosphorylation of the BCR-ABL fusion protein. Required for rapid phosphorylation of FER in response to FCER1 activation. Mediates KIT phosphorylation. Acts as an effector of EPOR (erythropoietin receptor) in controlling KIT expression and may play a role in erythroid differentiation during the switch between proliferation and maturation. Depending on the context, activates or inhibits several signaling cascades. Regulates phosphatidylinositol 3-kinase activity and AKT1 activation. Regulates activation of the MAP kinase signaling cascade, including activation of MAP2K1/MEK1, MAPK1/ERK2, MAPK3/ERK1, MAPK8/JNK1 and MAPK9/JNK2. Mediates activation of STAT5A and/or STAT5B. Phosphorylates LPXN on Tyr-72. Kinase activity facilitates TLR4-TLR6 heterodimerization and signal initiation. Phosphorylates SCIMP on Tyr-107; this enhances binding of SCIMP to TLR4, promoting the phosphorylation of TLR4, and a selective cytokine response to lipopolysaccharide in macrophages . Phosphorylates CLNK . [View more on UniProt]
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No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI000337 | MOD_SPalmitoyl_4 | MOD | 1 | 7 | - |
ELMI000132 | MOD_TYR_CSK | MOD | 504 | 512 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in LYN_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 30.2326 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 30.2326 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 29.8450 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 23.2558 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 23.2558 | 5 | yes |
GO:0005524 | ATP binding | 22.8682 | 5 | yes |
GO:0046872 | metal ion binding | 21.3178 | 4 | no |
GO:0016301 | kinase activity | 18.2171 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 17.4419 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 16.6667 | 4 | yes |
GO:0004713 | protein tyrosine kinase activity | 7.7519 | 4 | yes |
GO:0044389 | ubiquitin-like protein ligase binding | 5.8140 | 4 | yes |
GO:0031625 | ubiquitin protein ligase binding | 5.4264 | 5 | yes |
GO:0070851 | growth factor receptor binding | 5.0388 | 4 | yes |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 4.6512 | 5 | yes |
GO:0046875 | ephrin receptor binding | 4.2636 | 4 | yes |
GO:0015631 | tubulin binding | 3.8760 | 4 | yes |
GO:0017124 | SH3 domain binding | 3.8760 | 4 | yes |
GO:0043015 | gamma-tubulin binding | 1.9380 | 5 | yes |
GO:0005161 | platelet-derived growth factor receptor binding | 1.1628 | 5 | yes |
GO:0140031 | phosphorylation-dependent protein binding | 1.1628 | 4 | yes |
GO:0043208 | glycosphingolipid binding | 0.7752 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in LYN_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 61.6279 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 51.1628 | 4 | yes |
GO:0010646 | regulation of cell communication | 47.6744 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 43.4109 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 43.4109 | 4 | yes |
GO:0009966 | regulation of signal transduction | 42.2481 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 40.6977 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 40.3101 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 39.5349 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 38.3721 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 35.2713 | 5 | yes |
GO:0022607 | cellular component assembly | 34.1085 | 4 | no |
GO:0048584 | positive regulation of response to stimulus | 34.1085 | 4 | yes |
GO:1902531 | regulation of intracellular signal transduction | 33.7209 | 5 | yes |
GO:0051049 | regulation of transport | 32.9457 | 4 | yes |
GO:0031325 | positive regulation of cellular metabolic process | 32.5581 | 5 | yes |
GO:0051246 | regulation of protein metabolic process | 32.5581 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 31.3953 | 5 | yes |
GO:0006996 | organelle organization | 31.0078 | 4 | no |
GO:0023056 | positive regulation of signaling | 31.0078 | 4 | yes |
GO:0010468 | regulation of gene expression | 30.6202 | 5 | yes |
GO:0010647 | positive regulation of cell communication | 30.6202 | 5 | yes |
GO:0008104 | protein localization | 28.2946 | 4 | no |
GO:0019220 | regulation of phosphate metabolic process | 27.9070 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 27.9070 | 5 | yes |
GO:0009967 | positive regulation of signal transduction | 27.5194 | 5 | yes |
GO:0031399 | regulation of protein modification process | 26.7442 | 6 | yes |
GO:0030030 | cell projection organization | 25.9690 | 4 | yes |
GO:0042325 | regulation of phosphorylation | 25.9690 | 7 | yes |
GO:0051247 | positive regulation of protein metabolic process | 25.9690 | 6 | yes |
GO:0071310 | cellular response to organic substance | 25.5814 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 25.5814 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 25.1938 | 4 | no |
GO:0042127 | regulation of cell population proliferation | 24.4186 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 24.4186 | 5 | yes |
GO:0009892 | negative regulation of metabolic process | 24.0310 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 24.0310 | 4 | no |
GO:0043085 | positive regulation of catalytic activity | 24.0310 | 4 | yes |
GO:0031326 | regulation of cellular biosynthetic process | 23.6434 | 5 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 23.2558 | 6 | yes |
GO:0010941 | regulation of cell death | 23.2558 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 23.2558 | 4 | yes |
GO:0043412 | macromolecule modification | 23.2558 | 4 | yes |
GO:0045595 | regulation of cell differentiation | 23.2558 | 4 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 23.2558 | 7 | yes |
GO:0001932 | regulation of protein phosphorylation | 23.2558 | 7 | yes |
GO:2000145 | regulation of cell motility | 22.8682 | 4 | yes |
GO:0007010 | cytoskeleton organization | 22.8682 | 5 | no |
GO:0036211 | protein modification process | 22.8682 | 4 | yes |
GO:0071702 | organic substance transport | 22.8682 | 4 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.4806 | 5 | no |
GO:0044087 | regulation of cellular component biogenesis | 22.0930 | 4 | no |
GO:0030334 | regulation of cell migration | 22.0930 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 22.0930 | 4 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 21.7054 | 5 | yes |
GO:0042327 | positive regulation of phosphorylation | 21.7054 | 8 | yes |
GO:0043067 | regulation of programmed cell death | 21.7054 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 21.7054 | 4 | yes |
GO:0010556 | regulation of macromolecule biosynthetic process | 21.3178 | 5 | no |
GO:0042981 | regulation of apoptotic process | 21.3178 | 6 | yes |
GO:0033043 | regulation of organelle organization | 20.9302 | 5 | no |
GO:0031401 | positive regulation of protein modification process | 20.9302 | 7 | yes |
GO:0048585 | negative regulation of response to stimulus | 20.9302 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 20.9302 | 6 | yes |
GO:0010648 | negative regulation of cell communication | 20.5426 | 5 | yes |
GO:0060341 | regulation of cellular localization | 20.5426 | 4 | no |
GO:0023057 | negative regulation of signaling | 20.5426 | 4 | yes |
GO:0071705 | nitrogen compound transport | 20.5426 | 4 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 20.1550 | 5 | yes |
GO:0031344 | regulation of cell projection organization | 19.7674 | 5 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 19.3798 | 5 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 19.3798 | 5 | yes |
GO:0051336 | regulation of hydrolase activity | 19.3798 | 4 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 19.3798 | 8 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 19.3798 | 6 | yes |
GO:0007167 | enzyme-linked receptor protein signaling pathway | 18.9922 | 4 | yes |
GO:0043408 | regulation of MAPK cascade | 18.9922 | 6 | yes |
GO:0080134 | regulation of response to stress | 18.9922 | 4 | yes |
GO:2000026 | regulation of multicellular organismal development | 18.6047 | 4 | yes |
GO:0016310 | phosphorylation | 18.6047 | 5 | yes |
GO:0051338 | regulation of transferase activity | 18.2171 | 4 | yes |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 17.8295 | 5 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 17.8295 | 4 | yes |
GO:0010243 | response to organonitrogen compound | 17.4419 | 4 | yes |
GO:0008284 | positive regulation of cell population proliferation | 17.0543 | 5 | yes |
GO:0009968 | negative regulation of signal transduction | 17.0543 | 5 | yes |
GO:0030155 | regulation of cell adhesion | 17.0543 | 4 | yes |
GO:0043549 | regulation of kinase activity | 16.6667 | 5 | yes |
GO:0006468 | protein phosphorylation | 16.6667 | 5 | yes |
GO:0002684 | positive regulation of immune system process | 16.2791 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 15.8915 | 5 | yes |
GO:0030335 | positive regulation of cell migration | 15.8915 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 15.8915 | 4 | yes |
GO:0051241 | negative regulation of multicellular organismal process | 15.5039 | 4 | yes |
GO:0051347 | positive regulation of transferase activity | 15.5039 | 5 | yes |
GO:0032101 | regulation of response to external stimulus | 15.1163 | 4 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 15.1163 | 4 | yes |
GO:0045597 | positive regulation of cell differentiation | 14.7287 | 5 | yes |
GO:0050776 | regulation of immune response | 14.7287 | 4 | yes |
GO:0033674 | positive regulation of kinase activity | 14.3411 | 6 | yes |
GO:0043269 | regulation of ion transport | 14.3411 | 5 | yes |
GO:0045859 | regulation of protein kinase activity | 14.3411 | 6 | yes |
GO:0051248 | negative regulation of protein metabolic process | 14.3411 | 6 | yes |
GO:0014070 | response to organic cyclic compound | 13.5659 | 4 | yes |
GO:0018193 | peptidyl-amino acid modification | 13.5659 | 5 | yes |
GO:0031346 | positive regulation of cell projection organization | 13.1783 | 6 | yes |
GO:0051345 | positive regulation of hydrolase activity | 12.7907 | 5 | yes |
GO:0010975 | regulation of neuron projection development | 12.4031 | 7 | yes |
GO:0031175 | neuron projection development | 12.4031 | 6 | yes |
GO:0051093 | negative regulation of developmental process | 12.4031 | 4 | yes |
GO:0034762 | regulation of transmembrane transport | 12.0155 | 4 | yes |
GO:0051046 | regulation of secretion | 12.0155 | 5 | yes |
GO:0008285 | negative regulation of cell population proliferation | 11.6279 | 5 | yes |
GO:0010942 | positive regulation of cell death | 11.6279 | 5 | yes |
GO:0010959 | regulation of metal ion transport | 11.6279 | 6 | yes |
GO:1903530 | regulation of secretion by cell | 11.2403 | 4 | yes |
GO:0050865 | regulation of cell activation | 11.2403 | 4 | yes |
GO:0060284 | regulation of cell development | 11.2403 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 10.8527 | 7 | yes |
GO:0050778 | positive regulation of immune response | 10.8527 | 5 | yes |
GO:0001817 | regulation of cytokine production | 10.8527 | 4 | yes |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 10.8527 | 7 | yes |
GO:0080135 | regulation of cellular response to stress | 10.8527 | 4 | yes |
GO:0030162 | regulation of proteolysis | 10.4651 | 6 | yes |
GO:0043065 | positive regulation of apoptotic process | 10.4651 | 7 | yes |
GO:0043068 | positive regulation of programmed cell death | 10.4651 | 6 | yes |
GO:0006811 | ion transport | 10.0775 | 4 | yes |
GO:0033993 | response to lipid | 10.0775 | 4 | yes |
GO:0002694 | regulation of leukocyte activation | 10.0775 | 4 | yes |
GO:1902532 | negative regulation of intracellular signal transduction | 10.0775 | 6 | yes |
GO:0034765 | regulation of ion transmembrane transport | 9.6899 | 5 | yes |
GO:0043086 | negative regulation of catalytic activity | 9.6899 | 4 | yes |
GO:0045785 | positive regulation of cell adhesion | 9.6899 | 5 | yes |
GO:0006812 | cation transport | 9.3023 | 5 | yes |
GO:1904062 | regulation of cation transmembrane transport | 9.3023 | 6 | yes |
GO:0010563 | negative regulation of phosphorus metabolic process | 9.3023 | 6 | yes |
GO:0022407 | regulation of cell-cell adhesion | 9.3023 | 5 | yes |
GO:0045596 | negative regulation of cell differentiation | 9.3023 | 5 | yes |
GO:0045936 | negative regulation of phosphate metabolic process | 9.3023 | 7 | yes |
GO:0031347 | regulation of defense response | 8.9147 | 5 | yes |
GO:0046903 | secretion | 8.9147 | 4 | yes |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 8.9147 | 8 | yes |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 8.9147 | 4 | yes |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 8.9147 | 4 | yes |
GO:0042326 | negative regulation of phosphorylation | 8.5271 | 8 | yes |
GO:0051249 | regulation of lymphocyte activation | 8.5271 | 5 | yes |
GO:0071900 | regulation of protein serine/threonine kinase activity | 8.5271 | 7 | yes |
GO:0010720 | positive regulation of cell development | 8.1395 | 6 | yes |
GO:0032103 | positive regulation of response to external stimulus | 8.1395 | 5 | yes |
GO:0046777 | protein autophosphorylation | 8.1395 | 6 | yes |
GO:0051960 | regulation of nervous system development | 8.1395 | 5 | yes |
GO:1901652 | response to peptide | 8.1395 | 4 | yes |
GO:0001933 | negative regulation of protein phosphorylation | 7.7519 | 8 | yes |
GO:0019216 | regulation of lipid metabolic process | 7.3643 | 5 | yes |
GO:0050767 | regulation of neurogenesis | 7.3643 | 6 | yes |
GO:0050863 | regulation of T cell activation | 7.3643 | 6 | yes |
GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 6.9767 | 9 | yes |
GO:0050867 | positive regulation of cell activation | 6.9767 | 5 | yes |
GO:0051924 | regulation of calcium ion transport | 6.9767 | 7 | yes |
GO:0071396 | cellular response to lipid | 6.9767 | 5 | yes |
GO:0006887 | exocytosis | 6.5891 | 4 | yes |
GO:0018108 | peptidyl-tyrosine phosphorylation | 6.5891 | 6 | yes |
GO:0018212 | peptidyl-tyrosine modification | 6.5891 | 6 | yes |
GO:0045862 | positive regulation of proteolysis | 6.5891 | 7 | yes |
GO:0002696 | positive regulation of leukocyte activation | 6.5891 | 5 | yes |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 6.2016 | 6 | yes |
GO:0043434 | response to peptide hormone | 6.2016 | 4 | yes |
GO:0052547 | regulation of peptidase activity | 6.2016 | 5 | yes |
GO:0052548 | regulation of endopeptidase activity | 6.2016 | 6 | yes |
GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 6.2016 | 5 | yes |
GO:0002683 | negative regulation of immune system process | 6.2016 | 4 | yes |
GO:0002831 | regulation of response to biotic stimulus | 6.2016 | 4 | yes |
GO:0010976 | positive regulation of neuron projection development | 5.8140 | 7 | yes |
GO:0017157 | regulation of exocytosis | 5.8140 | 5 | yes |
GO:0045834 | positive regulation of lipid metabolic process | 5.8140 | 5 | yes |
GO:0050851 | antigen receptor-mediated signaling pathway | 5.8140 | 5 | yes |
GO:0051251 | positive regulation of lymphocyte activation | 5.8140 | 6 | yes |
GO:0051348 | negative regulation of transferase activity | 5.8140 | 5 | yes |
GO:0051962 | positive regulation of nervous system development | 5.8140 | 5 | yes |
GO:0002685 | regulation of leukocyte migration | 5.8140 | 4 | yes |
GO:0006974 | cellular response to DNA damage stimulus | 5.4264 | 4 | yes |
GO:1903706 | regulation of hemopoiesis | 5.4264 | 4 | yes |
GO:0031349 | positive regulation of defense response | 5.4264 | 5 | yes |
GO:0032102 | negative regulation of response to external stimulus | 5.4264 | 5 | yes |
GO:0043405 | regulation of MAP kinase activity | 5.4264 | 8 | yes |
GO:0048013 | ephrin receptor signaling pathway | 5.4264 | 6 | yes |
GO:0050769 | positive regulation of neurogenesis | 5.4264 | 6 | yes |
GO:0050920 | regulation of chemotaxis | 5.4264 | 4 | yes |
GO:0002521 | leukocyte differentiation | 5.4264 | 4 | yes |
GO:1903131 | mononuclear cell differentiation | 5.0388 | 5 | yes |
GO:0022409 | positive regulation of cell-cell adhesion | 5.0388 | 6 | yes |
GO:0033673 | negative regulation of kinase activity | 5.0388 | 6 | yes |
GO:0043409 | negative regulation of MAPK cascade | 5.0388 | 7 | yes |
GO:0070663 | regulation of leukocyte proliferation | 5.0388 | 5 | yes |
GO:0006469 | negative regulation of protein kinase activity | 5.0388 | 7 | yes |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 4.6512 | 7 | yes |
GO:1903305 | regulation of regulated secretory pathway | 4.6512 | 6 | yes |
GO:0038093 | Fc receptor signaling pathway | 4.6512 | 5 | yes |
GO:0045088 | regulation of innate immune response | 4.6512 | 5 | yes |
GO:0050727 | regulation of inflammatory response | 4.6512 | 5 | yes |
GO:0050870 | positive regulation of T cell activation | 4.6512 | 7 | yes |
GO:0051282 | regulation of sequestering of calcium ion | 4.6512 | 4 | yes |
GO:0070304 | positive regulation of stress-activated protein kinase signaling cascade | 4.6512 | 6 | yes |
GO:0009743 | response to carbohydrate | 4.2636 | 4 | yes |
GO:0038094 | Fc-gamma receptor signaling pathway | 4.2636 | 6 | yes |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 4.2636 | 4 | yes |
GO:0043200 | response to amino acid | 4.2636 | 4 | yes |
GO:0045637 | regulation of myeloid cell differentiation | 4.2636 | 5 | yes |
GO:0002431 | Fc receptor mediated stimulatory signaling pathway | 4.2636 | 5 | yes |
GO:0002688 | regulation of leukocyte chemotaxis | 4.2636 | 5 | yes |
GO:0002833 | positive regulation of response to biotic stimulus | 4.2636 | 5 | yes |
GO:1903169 | regulation of calcium ion transmembrane transport | 3.8760 | 7 | yes |
GO:0010950 | positive regulation of endopeptidase activity | 3.8760 | 7 | yes |
GO:0010952 | positive regulation of peptidase activity | 3.8760 | 6 | yes |
GO:0023061 | signal release | 3.8760 | 4 | yes |
GO:0031348 | negative regulation of defense response | 3.8760 | 5 | yes |
GO:0032868 | response to insulin | 3.8760 | 5 | yes |
GO:0032944 | regulation of mononuclear cell proliferation | 3.8760 | 6 | yes |
GO:0043550 | regulation of lipid kinase activity | 3.8760 | 6 | yes |
GO:0043551 | regulation of phosphatidylinositol 3-kinase activity | 3.8760 | 7 | yes |
GO:0045055 | regulated exocytosis | 3.8760 | 5 | yes |
GO:0050670 | regulation of lymphocyte proliferation | 3.8760 | 6 | yes |
GO:0071675 | regulation of mononuclear cell migration | 3.8760 | 5 | yes |
GO:1902105 | regulation of leukocyte differentiation | 3.8760 | 5 | yes |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 3.4884 | 7 | yes |
GO:0045089 | positive regulation of innate immune response | 3.4884 | 6 | yes |
GO:0050728 | negative regulation of inflammatory response | 3.4884 | 6 | yes |
GO:0050777 | negative regulation of immune response | 3.4884 | 5 | yes |
GO:0050853 | B cell receptor signaling pathway | 3.4884 | 6 | yes |
GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 3.4884 | 5 | yes |
GO:0090218 | positive regulation of lipid kinase activity | 3.4884 | 6 | yes |
GO:2000177 | regulation of neural precursor cell proliferation | 3.1008 | 5 | yes |
GO:0030099 | myeloid cell differentiation | 3.1008 | 4 | yes |
GO:0050866 | negative regulation of cell activation | 3.1008 | 5 | yes |
GO:0062207 | regulation of pattern recognition receptor signaling pathway | 3.1008 | 5 | yes |
GO:0070373 | negative regulation of ERK1 and ERK2 cascade | 3.1008 | 8 | yes |
GO:0002697 | regulation of immune effector process | 3.1008 | 4 | yes |
GO:0071901 | negative regulation of protein serine/threonine kinase activity | 3.1008 | 8 | yes |
GO:0009914 | hormone transport | 2.7132 | 4 | yes |
GO:0034110 | regulation of homotypic cell-cell adhesion | 2.7132 | 6 | yes |
GO:0042509 | regulation of tyrosine phosphorylation of STAT protein | 2.7132 | 9 | yes |
GO:0046879 | hormone secretion | 2.7132 | 5 | yes |
GO:0048872 | homeostasis of number of cells | 2.7132 | 4 | yes |
GO:0070665 | positive regulation of leukocyte proliferation | 2.7132 | 6 | yes |
GO:0002695 | negative regulation of leukocyte activation | 2.7132 | 5 | yes |
GO:0002703 | regulation of leukocyte mediated immunity | 2.7132 | 5 | yes |
GO:0002758 | innate immune response-activating signal transduction | 2.7132 | 4 | yes |
GO:0002861 | regulation of inflammatory response to antigenic stimulus | 2.7132 | 5 | yes |
GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 2.7132 | 6 | yes |
GO:1902991 | regulation of amyloid precursor protein catabolic process | 2.3256 | 6 | yes |
GO:1990858 | cellular response to lectin | 2.3256 | 4 | yes |
GO:0010543 | regulation of platelet activation | 2.3256 | 5 | yes |
GO:0021782 | glial cell development | 2.3256 | 4 | yes |
GO:0032945 | negative regulation of mononuclear cell proliferation | 2.3256 | 7 | yes |
GO:0033628 | regulation of cell adhesion mediated by integrin | 2.3256 | 5 | yes |
GO:0034121 | regulation of toll-like receptor signaling pathway | 2.3256 | 6 | yes |
GO:0045646 | regulation of erythrocyte differentiation | 2.3256 | 6 | yes |
GO:0050672 | negative regulation of lymphocyte proliferation | 2.3256 | 7 | yes |
GO:0051250 | negative regulation of lymphocyte activation | 2.3256 | 6 | yes |
GO:0002220 | innate immune response activating cell surface receptor signaling pathway | 2.3256 | 5 | yes |
GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 2.3256 | 5 | yes |
GO:0070664 | negative regulation of leukocyte proliferation | 2.3256 | 6 | yes |
GO:0002699 | positive regulation of immune effector process | 2.3256 | 5 | yes |
GO:0002761 | regulation of myeloid leukocyte differentiation | 2.3256 | 6 | yes |
GO:1903707 | negative regulation of hemopoiesis | 1.9380 | 5 | yes |
GO:2000179 | positive regulation of neural precursor cell proliferation | 1.9380 | 6 | yes |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | 1.9380 | 4 | yes |
GO:0034122 | negative regulation of toll-like receptor signaling pathway | 1.9380 | 6 | yes |
GO:0034605 | cellular response to heat | 1.9380 | 4 | yes |
GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | 1.9380 | 10 | yes |
GO:0043300 | regulation of leukocyte degranulation | 1.9380 | 5 | yes |
GO:0043407 | negative regulation of MAP kinase activity | 1.9380 | 8 | yes |
GO:0045638 | negative regulation of myeloid cell differentiation | 1.9380 | 6 | yes |
GO:0060396 | growth hormone receptor signaling pathway | 1.9380 | 6 | yes |
GO:0090330 | regulation of platelet aggregation | 1.9380 | 6 | yes |
GO:0002886 | regulation of myeloid leukocyte mediated immunity | 1.9380 | 6 | yes |
GO:1902106 | negative regulation of leukocyte differentiation | 1.9380 | 6 | yes |
GO:1902961 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | 1.5504 | 8 | yes |
GO:1902993 | positive regulation of amyloid precursor protein catabolic process | 1.5504 | 7 | yes |
GO:1905245 | regulation of aspartic-type peptidase activity | 1.5504 | 6 | yes |
GO:1905247 | positive regulation of aspartic-type peptidase activity | 1.5504 | 7 | yes |
GO:0014013 | regulation of gliogenesis | 1.5504 | 7 | yes |
GO:0032526 | response to retinoic acid | 1.5504 | 4 | yes |
GO:0034143 | regulation of toll-like receptor 4 signaling pathway | 1.5504 | 7 | yes |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.5504 | 6 | yes |
GO:0048678 | response to axon injury | 1.5504 | 4 | yes |
GO:0050854 | regulation of antigen receptor-mediated signaling pathway | 1.5504 | 5 | yes |
GO:0050864 | regulation of B cell activation | 1.5504 | 6 | yes |
GO:0060397 | growth hormone receptor signaling pathway via JAK-STAT | 1.5504 | 7 | yes |
GO:0071300 | cellular response to retinoic acid | 1.5504 | 5 | yes |
GO:0002762 | negative regulation of myeloid leukocyte differentiation | 1.5504 | 7 | yes |
GO:1902959 | regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | 1.5504 | 7 | yes |
GO:0030218 | erythrocyte differentiation | 1.1628 | 5 | yes |
GO:0030888 | regulation of B cell proliferation | 1.1628 | 7 | yes |
GO:0033003 | regulation of mast cell activation | 1.1628 | 5 | yes |
GO:0033006 | regulation of mast cell activation involved in immune response | 1.1628 | 5 | yes |
GO:0034135 | regulation of toll-like receptor 2 signaling pathway | 1.1628 | 7 | yes |
GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway | 1.1628 | 7 | yes |
GO:0043304 | regulation of mast cell degranulation | 1.1628 | 6 | yes |
GO:0050855 | regulation of B cell receptor signaling pathway | 1.1628 | 6 | yes |
GO:0051608 | histamine transport | 1.1628 | 5 | yes |
GO:0001782 | B cell homeostasis | 1.1628 | 4 | yes |
GO:0001821 | histamine secretion | 1.1628 | 5 | yes |
GO:0002221 | pattern recognition receptor signaling pathway | 1.1628 | 4 | yes |
GO:0002224 | toll-like receptor signaling pathway | 1.1628 | 5 | yes |
GO:0002441 | histamine secretion involved in inflammatory response | 1.1628 | 6 | yes |
GO:0090025 | regulation of monocyte chemotaxis | 1.1628 | 6 | yes |
GO:0097028 | dendritic cell differentiation | 1.1628 | 6 | yes |
GO:2000106 | regulation of leukocyte apoptotic process | 0.7752 | 7 | yes |
GO:2000108 | positive regulation of leukocyte apoptotic process | 0.7752 | 8 | yes |
GO:2000668 | regulation of dendritic cell apoptotic process | 0.7752 | 8 | yes |
GO:2000670 | positive regulation of dendritic cell apoptotic process | 0.7752 | 9 | yes |
GO:0014003 | oligodendrocyte development | 0.7752 | 5 | yes |
GO:0014015 | positive regulation of gliogenesis | 0.7752 | 7 | yes |
GO:0030889 | negative regulation of B cell proliferation | 0.7752 | 8 | yes |
GO:0034136 | negative regulation of toll-like receptor 2 signaling pathway | 0.7752 | 7 | yes |
GO:0034142 | toll-like receptor 4 signaling pathway | 0.7752 | 6 | yes |
GO:0050869 | negative regulation of B cell activation | 0.7752 | 7 | yes |
GO:0060251 | regulation of glial cell proliferation | 0.7752 | 5 | yes |
GO:0060252 | positive regulation of glial cell proliferation | 0.7752 | 6 | yes |
GO:0060368 | regulation of Fc receptor mediated stimulatory signaling pathway | 0.7752 | 5 | yes |
GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway | 0.7752 | 6 | yes |
GO:0070228 | regulation of lymphocyte apoptotic process | 0.7752 | 8 | yes |
GO:0070445 | regulation of oligodendrocyte progenitor proliferation | 0.7752 | 6 | yes |
GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation | 0.7752 | 7 | yes |
GO:0070666 | regulation of mast cell proliferation | 0.7752 | 6 | yes |
GO:0002576 | platelet degranulation | 0.7752 | 4 | yes |
GO:0070667 | negative regulation of mast cell proliferation | 0.7752 | 7 | yes |
GO:0070668 | positive regulation of mast cell proliferation | 0.7752 | 7 | yes |
GO:0002765 | immune response-inhibiting signal transduction | 0.7752 | 4 | yes |
GO:0002767 | immune response-inhibiting cell surface receptor signaling pathway | 0.7752 | 5 | yes |
GO:0002774 | Fc receptor mediated inhibitory signaling pathway | 0.7752 | 6 | yes |
GO:0002902 | regulation of B cell apoptotic process | 0.7752 | 9 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in LYN_HUMAN |
---|---|---|---|---|
DOID:0060038 | specific developmental disorder | 1.9380 | 3 | no |
DOID:1059 | intellectual disability | 1.9380 | 4 | no |
DOID:114 | heart disease | 1.9380 | 3 | no |
DOID:612 | primary immunodeficiency disease | 1.9380 | 3 | no |
DOID:0060307 | autosomal dominant intellectual developmental disorder | 1.5504 | 5 | no |
DOID:0050700 | cardiomyopathy | 1.5504 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 1.5504 | 5 | no |
DOID:1289 | neurodegenerative disease | 1.5504 | 4 | no |
DOID:331 | central nervous system disease | 1.5504 | 3 | no |
DOID:0050686 | organ system cancer | 1.5504 | 3 | no |
DOID:0111962 | combined immunodeficiency | 1.1628 | 4 | no |
DOID:10534 | stomach cancer | 0.7752 | 5 | no |
DOID:193 | reproductive organ cancer | 0.7752 | 4 | no |
DOID:3119 | gastrointestinal system cancer | 0.7752 | 4 | no |
DOID:557 | kidney disease | 0.7752 | 3 | no |
DOID:627 | severe combined immunodeficiency | 0.7752 | 5 | no |
DOID:0050155 | sensory system disease | 0.7752 | 3 | no |
DOID:0050563 | nonsyndromic deafness | 0.7752 | 5 | no |
DOID:0050564 | autosomal dominant nonsyndromic deafness | 0.7752 | 6 | no |
DOID:2742 | auditory system disease | 0.7752 | 4 | no |
DOID:231 | motor neuron disease | 0.7752 | 5 | no |
DOID:12930 | dilated cardiomyopathy | 0.7752 | 6 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
TNFL6_HUMAN | [view interactions] | Low throughput | no | yes |
GPVI_HUMAN | [view interactions] | Low throughput | no | no |
CIP4_HUMAN | [view interactions] | Low throughput | no | no |
HNRPK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DOK1_HUMAN | [view interactions] | Low throughput | no | yes |
EFS_HUMAN | [view interactions] | Low throughput | no | no |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
HCLS1_HUMAN | [view interactions] | Low throughput | no | no |
ARAP3_HUMAN | [view interactions] | Low throughput | no | no |
MCM7_HUMAN | [view interactions] | Low throughput | no | no |
ITA2_HUMAN | [view interactions] | Low throughput | no | yes |
CDK1_HUMAN | [view interactions] | Low throughput | no | no |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BCAP_HUMAN | [view interactions] | Low throughput | no | no |
CD19_HUMAN | [view interactions] | Low throughput | no | no |
GP1BA_HUMAN | [view interactions] | Low throughput | no | no |
FLT3_HUMAN | [view interactions] | Low throughput | no | no |
IL1R1_HUMAN | [view interactions] | Low throughput | no | no |
VP13A_HUMAN | [view interactions] | Low throughput | no | yes |
ATG7_HUMAN | [view interactions] | Low throughput | no | yes |
PGFRA_HUMAN | [view interactions] | Low throughput | no | no |
BANK1_HUMAN | [view interactions] | Low throughput | no | no |
CD79A_HUMAN | [view interactions] | Low throughput | no | no |
FAK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBL_HUMAN | [view interactions] | Low throughput | no | yes |
CD22_HUMAN | [view interactions] | Low throughput | no | no |
KHDR1_HUMAN | [view interactions] | Low throughput | no | yes |
CLNK_HUMAN | [view interactions] | Low throughput | no | no |
KPCD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SHC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SKAP2_HUMAN | [view interactions] | Low throughput | no | no |
FYB1_HUMAN | [view interactions] | Low throughput | no | no |
ASAP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
3BP2_HUMAN | [view interactions] | Low throughput | no | yes |
PLCG2_HUMAN | [view interactions] | Low throughput | no | yes |
P85A_HUMAN | [view interactions] | Low throughput | no | yes |
CBLB_HUMAN | [view interactions] | Low throughput | no | yes |
FCG2B_HUMAN | [view interactions] | Low throughput | no | no |
EPOR_HUMAN | [view interactions] | Low throughput | no | no |
CENPV_HUMAN | [view interactions] | Low throughput | no | yes |
CD36_HUMAN | [view interactions] | Low throughput | no | no |
CSF1R_HUMAN | [view interactions] | Low throughput | no | yes |
PDE4A_HUMAN | [view interactions] | Low throughput | no | no |
JAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SKAP1_HUMAN | [view interactions] | Low throughput | no | no |
BTK_HUMAN | [view interactions] | Low throughput | no | no |
PRKDC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
EVL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TYK2_HUMAN | [view interactions] | Low throughput | no | no |
RL10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CBLC_HUMAN | [view interactions] | Low throughput | no | yes |
CBP_HUMAN | [view interactions] | Low throughput | no | yes |
TNFA_HUMAN | [view interactions] | Low throughput | no | no |
ITB3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
IL1B_HUMAN | [view interactions] | Low throughput | no | no |
ITB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
SPHK2_HUMAN | [view interactions] | Low throughput | no | no |
SPHK1_HUMAN | [view interactions] | Low throughput | no | yes |
NMT1_HUMAN | [view interactions] | Low throughput | no | yes |
EGFR_HUMAN | [view interactions] | Low throughput | no | no |
CD72_HUMAN | [view interactions] | Low throughput | no | no |
CDN1B_HUMAN | [view interactions] | Low throughput | no | yes |
PP1R8_HUMAN | [view interactions] | Low throughput | no | yes |
CRKL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ENOA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITA4_HUMAN | [view interactions] | Low throughput | no | no |
RGS16_HUMAN | [view interactions] | Low throughput | no | no |
PHAG1_HUMAN | [view interactions] | Low throughput | no | yes |
TIF1B_HUMAN | [view interactions] | Low throughput | no | yes |
STAT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
COASY_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SOCS1_HUMAN | [view interactions] | Low throughput | no | yes |
PTN6_HUMAN | [view interactions] | Low throughput | no | no |
ULK1_HUMAN | [view interactions] | Low throughput | no | no |
CD24_HUMAN | [view interactions] | Low throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DOCK8_HUMAN | [view interactions] | Low throughput | no | yes |
GAB2_HUMAN | [view interactions] | Low throughput | no | yes |
TNR11_HUMAN | [view interactions] | Low throughput | no | yes |
SRC8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
IRS2_HUMAN | [view interactions] | Low throughput | no | yes |
BCAR1_HUMAN | [view interactions] | Low throughput | no | yes |
DOK2_HUMAN | [view interactions] | Low throughput | no | no |
DBNL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
LYN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
KIT_HUMAN | [view interactions] | Low throughput | no | no |
PR15A_HUMAN | [view interactions] | Low throughput | no | yes |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MUC1_HUMAN | [view interactions] | Low throughput | no | no |
SHIP1_HUMAN | [view interactions] | Low throughput | no | no |
PRAM_HUMAN | [view interactions] | Low throughput | no | no |
U119A_HUMAN | [view interactions] | Low throughput | no | no |
TEC_HUMAN | [view interactions] | Low throughput | no | yes |
FAK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KSYK_HUMAN | [view interactions] | Low throughput | no | no |
NEP_HUMAN | [view interactions] | Low throughput | no | no |
CASL_HUMAN | [view interactions] | Low throughput | no | yes |
LCP2_HUMAN | [view interactions] | Low throughput | no | yes |
FCG2A_HUMAN | [view interactions] | Low throughput | no | no |
PECA1_HUMAN | [view interactions] | Low throughput | no | no |
PK3CG_HUMAN | [view interactions] | Low throughput | no | yes |
PTPRC_HUMAN | [view interactions] | Low throughput | no | no |
CTLA4_HUMAN | [view interactions] | Low throughput | no | no |
TRPV4_HUMAN | [view interactions] | Low throughput | no | yes |
CSF3R_HUMAN | [view interactions] | Low throughput | no | yes |
IL3RB_HUMAN | [view interactions] | Low throughput | no | no |
CDK2_HUMAN | [view interactions] | Low throughput | no | yes |
FCAR_HUMAN | [view interactions] | Low throughput | no | no |
NFIP2_HUMAN | [view interactions] | Low throughput | no | yes |
FCERB_HUMAN | [view interactions] | Low throughput | no | no |
FGFR2_HUMAN | [view interactions] | Low throughput | no | yes |
P53_HUMAN | [view interactions] | Low throughput | no | no |
GAB3_HUMAN | [view interactions] | Low throughput | no | yes |
ACK1_HUMAN | [view interactions] | Low throughput | no | yes |
PDE4D_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ACSL3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ZN189_HUMAN | [view interactions] | High throughput | no | yes |
EPHA3_HUMAN | [view interactions] | High throughput | no | yes |
SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FRS2_HUMAN | [view interactions] | High throughput | no | no |
EPHA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UPAR_HUMAN | [view interactions] | High throughput | no | yes |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
5HT2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SLIK4_HUMAN | [view interactions] | High throughput | no | yes |
ESYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANGP2_HUMAN | [view interactions] | High throughput | no | no |
EXOC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
YETS4_HUMAN | [view interactions] | High throughput | no | no |
NIBA2_HUMAN | [view interactions] | High throughput | no | no |
LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
F135A_HUMAN | [view interactions] | High throughput | no | yes |
TPTE2_HUMAN | [view interactions] | High throughput | no | no |
F1711_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TYW1_HUMAN | [view interactions] | High throughput | no | yes |
F1712_HUMAN | [view interactions] | High throughput | no | no |
RIMS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
F171B_HUMAN | [view interactions] | High throughput | no | yes |
OSB11_HUMAN | [view interactions] | High throughput | no | no |
FA83B_HUMAN | [view interactions] | High throughput | no | no |
CP4V2_HUMAN | [view interactions] | High throughput | no | yes |
FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TGDS_HUMAN | [view interactions] | High throughput | no | yes |
FARP2_HUMAN | [view interactions] | High throughput | no | yes |
DVL2_HUMAN | [view interactions] | High throughput | no | yes |
FCHO2_HUMAN | [view interactions] | High throughput | no | yes |
UGPA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FERM2_HUMAN | [view interactions] | High throughput | no | yes |
ZN423_HUMAN | [view interactions] | High throughput | no | no |
FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TTYH3_HUMAN | [view interactions] | High throughput | no | yes |
FLVC1_HUMAN | [view interactions] | High throughput | no | yes |
NKAPL_HUMAN | [view interactions] | High throughput | no | no |
FMN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERO1A_HUMAN | [view interactions] | High throughput | no | yes |
FMNL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FSD1L_HUMAN | [view interactions] | High throughput | no | yes |
FNBP1_HUMAN | [view interactions] | High throughput | no | yes |
ENPL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRPD4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NFYB_HUMAN | [view interactions] | High throughput | no | yes |
GRIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
GRIN3_HUMAN | [view interactions] | High throughput | no | yes |
RBM11_HUMAN | [view interactions] | High throughput | no | no |
HLAA_HUMAN | [view interactions] | High throughput | no | no |
TAD2A_HUMAN | [view interactions] | High throughput | no | no |
IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNA2_HUMAN | [view interactions] | High throughput | no | yes |
IGSF3_HUMAN | [view interactions] | High throughput | no | yes |
LRIQ3_HUMAN | [view interactions] | High throughput | no | no |
ILDR2_HUMAN | [view interactions] | High throughput | no | yes |
DEN2C_HUMAN | [view interactions] | High throughput | no | no |
IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CNO10_HUMAN | [view interactions] | High throughput | no | yes |
IQGA2_HUMAN | [view interactions] | High throughput | no | yes |
HDGR3_HUMAN | [view interactions] | High throughput | no | yes |
IRS4_HUMAN | [view interactions] | High throughput | no | no |
TNF12_HUMAN | [view interactions] | High throughput | no | yes |
JPH1_HUMAN | [view interactions] | High throughput | no | no |
PRUN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPT1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCNB2_HUMAN | [view interactions] | High throughput | no | no |
TMX1_HUMAN | [view interactions] | High throughput | no | no |
K0754_HUMAN | [view interactions] | High throughput | no | no |
TBB4A_HUMAN | [view interactions] | High throughput | no | yes |
SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GTPB3_HUMAN | [view interactions] | High throughput | no | yes |
K1522_HUMAN | [view interactions] | High throughput | no | yes |
MCL1_HUMAN | [view interactions] | High throughput | no | yes |
KDIS_HUMAN | [view interactions] | High throughput | no | yes |
ZCHC7_HUMAN | [view interactions] | High throughput | no | yes |
KI26B_HUMAN | [view interactions] | High throughput | no | yes |
ZN577_HUMAN | [view interactions] | High throughput | no | yes |
KIRR1_HUMAN | [view interactions] | High throughput | no | no |
TFDP3_HUMAN | [view interactions] | High throughput | no | no |
L2GL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DOXA1_HUMAN | [view interactions] | High throughput | no | yes |
LRRC1_HUMAN | [view interactions] | High throughput | no | yes |
E2F6_HUMAN | [view interactions] | High throughput | no | no |
LSR_HUMAN | [view interactions] | High throughput | no | yes |
CF298_HUMAN | [view interactions] | High throughput | no | yes |
LZTS2_HUMAN | [view interactions] | High throughput | no | no |
PKHH2_HUMAN | [view interactions] | High throughput | no | no |
MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S12A4_HUMAN | [view interactions] | High throughput | no | yes |
M3K21_HUMAN | [view interactions] | High throughput | no | yes |
FBX28_HUMAN | [view interactions] | High throughput | no | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
RHG19_HUMAN | [view interactions] | High throughput | no | yes |
M4K5_HUMAN | [view interactions] | High throughput | no | no |
DTL_HUMAN | [view interactions] | High throughput | no | no |
MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADAM9_HUMAN | [view interactions] | High throughput | no | no |
DDX21_HUMAN | [view interactions] | High throughput | no | yes |
MRP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ADA12_HUMAN | [view interactions] | High throughput | no | no |
SPESP_HUMAN | [view interactions] | High throughput | no | no |
MARK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADA15_HUMAN | [view interactions] | High throughput | no | yes |
SCG3_HUMAN | [view interactions] | High throughput | no | yes |
MARK3_HUMAN | [view interactions] | High throughput | no | yes |
ADA19_HUMAN | [view interactions] | High throughput | no | no |
S22AG_HUMAN | [view interactions] | High throughput | no | yes |
MALD2_HUMAN | [view interactions] | High throughput | no | yes |
TMG4_HUMAN | [view interactions] | High throughput | no | yes |
KYNU_HUMAN | [view interactions] | High throughput | no | no |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
CSK2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAIP1_HUMAN | [view interactions] | High throughput | no | yes |
MICA3_HUMAN | [view interactions] | High throughput | no | yes |
RASF8_HUMAN | [view interactions] | High throughput | no | yes |
MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RBM12_HUMAN | [view interactions] | High throughput | no | yes |
CAD23_HUMAN | [view interactions] | High throughput | no | yes |
EM55_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PALS2_HUMAN | [view interactions] | High throughput | no | yes |
MPP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ANR54_HUMAN | [view interactions] | High throughput | no | yes |
CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
MPZL1_HUMAN | [view interactions] | High throughput | no | yes |
KLF5_HUMAN | [view interactions] | High throughput | no | yes |
ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
MYO1B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S2541_HUMAN | [view interactions] | High throughput | no | no |
MYO1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HXB5_HUMAN | [view interactions] | High throughput | no | no |
MYO1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
T185A_HUMAN | [view interactions] | High throughput | no | no |
NDRG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP43_HUMAN | [view interactions] | High throughput | no | no |
CCNL2_HUMAN | [view interactions] | High throughput | no | yes |
NECT2_HUMAN | [view interactions] | High throughput | no | no |
MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
MERL_HUMAN | [view interactions] | High throughput | no | yes |
ANLN_HUMAN | [view interactions] | High throughput | no | yes |
TSNAX_HUMAN | [view interactions] | High throughput | no | yes |
NISCH_HUMAN | [view interactions] | High throughput | no | yes |
MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OSGEP_HUMAN | [view interactions] | High throughput | no | yes |
NOTC1_HUMAN | [view interactions] | High throughput | no | yes |
RFIP1_HUMAN | [view interactions] | High throughput | no | yes |
SLAI1_HUMAN | [view interactions] | High throughput | no | no |
NOTC2_HUMAN | [view interactions] | High throughput | no | yes |
FLNB_HUMAN | [view interactions] | High throughput | no | no |
NUMB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FACD2_HUMAN | [view interactions] | High throughput | no | no |
NUMBL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CALL3_HUMAN | [view interactions] | High throughput | no | yes |
TRI25_HUMAN | [view interactions] | High throughput | no | yes |
PACS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMR1A_HUMAN | [view interactions] | High throughput | no | no |
PAK4_HUMAN | [view interactions] | High throughput | no | yes |
KLC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DX39B_HUMAN | [view interactions] | High throughput | no | no |
PALM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SCIMP_HUMAN | [view interactions] | High throughput | no | no |
ARNT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DUS4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MED9_HUMAN | [view interactions] | High throughput | no | no |
PARD3_HUMAN | [view interactions] | High throughput | no | yes |
PRP4_HUMAN | [view interactions] | High throughput | no | yes |
RN138_HUMAN | [view interactions] | High throughput | no | no |
PCDH7_HUMAN | [view interactions] | High throughput | no | no |
HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
PDE8A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LARP7_HUMAN | [view interactions] | High throughput | no | yes |
PEAK1_HUMAN | [view interactions] | High throughput | no | yes |
HCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RN123_HUMAN | [view interactions] | High throughput | no | yes |
PHAR4_HUMAN | [view interactions] | High throughput | no | yes |
FGR_HUMAN | [view interactions] | High throughput | no | no |
DCPS_HUMAN | [view interactions] | High throughput | no | yes |
PHLB2_HUMAN | [view interactions] | High throughput | no | yes |
DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
P85B_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
PI51A_HUMAN | [view interactions] | High throughput | no | yes |
CCAR1_HUMAN | [view interactions] | High throughput | no | yes |
PKP2_HUMAN | [view interactions] | High throughput | no | yes |
ARGL1_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
PKP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRRM2_HUMAN | [view interactions] | High throughput | no | yes |
PLCB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRP8_HUMAN | [view interactions] | High throughput | no | yes |
PLCH1_HUMAN | [view interactions] | High throughput | no | no |
DDX23_HUMAN | [view interactions] | High throughput | no | yes |
A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H90B3_HUMAN | [view interactions] | High throughput | no | no |
NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
TPP2_HUMAN | [view interactions] | High throughput | no | yes |
PLXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LIPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSK23_HUMAN | [view interactions] | High throughput | no | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
ERH_HUMAN | [view interactions] | High throughput | no | yes |
YAP1_HUMAN | [view interactions] | High throughput | no | yes |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
DSG1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TFCP2_HUMAN | [view interactions] | High throughput | no | no |
NEB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SF3A3_HUMAN | [view interactions] | High throughput | no | yes |
EMC1_HUMAN | [view interactions] | High throughput | no | yes |
PSD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
KIF14_HUMAN | [view interactions] | High throughput | no | no |
PTK7_HUMAN | [view interactions] | High throughput | no | yes |
SF3A2_HUMAN | [view interactions] | High throughput | no | yes |
KI20A_HUMAN | [view interactions] | High throughput | no | yes |
PTN13_HUMAN | [view interactions] | High throughput | no | yes |
SF3A1_HUMAN | [view interactions] | High throughput | no | yes |
KIF23_HUMAN | [view interactions] | High throughput | no | yes |
PTN14_HUMAN | [view interactions] | High throughput | no | yes |
CHERP_HUMAN | [view interactions] | High throughput | no | no |
NUPR1_HUMAN | [view interactions] | High throughput | no | no |
PTPRG_HUMAN | [view interactions] | High throughput | no | no |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
RAB23_HUMAN | [view interactions] | High throughput | no | yes |
TR150_HUMAN | [view interactions] | High throughput | no | yes |
NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAI14_HUMAN | [view interactions] | High throughput | no | yes |
ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXB7_HUMAN | [view interactions] | High throughput | no | no |
RASA3_HUMAN | [view interactions] | High throughput | no | yes |
CERS2_HUMAN | [view interactions] | High throughput | no | no |
NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
SNPC1_HUMAN | [view interactions] | High throughput | no | no |
RELL1_HUMAN | [view interactions] | High throughput | no | yes |
PAR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
YES_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RICTR_HUMAN | [view interactions] | High throughput | no | yes |
BLMH_HUMAN | [view interactions] | High throughput | no | yes |
ROBO1_HUMAN | [view interactions] | High throughput | no | yes |
ABITM_HUMAN | [view interactions] | High throughput | no | yes |
ROBO2_HUMAN | [view interactions] | High throughput | no | yes |
ZDH23_HUMAN | [view interactions] | High throughput | no | no |
ROCK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAL4G_HUMAN | [view interactions] | High throughput | no | no |
ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAL4C_HUMAN | [view interactions] | High throughput | no | no |
SCAM1_HUMAN | [view interactions] | High throughput | no | no |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRIH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SCRB1_HUMAN | [view interactions] | High throughput | no | no |
ST38L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SCRIB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TBD_HUMAN | [view interactions] | High throughput | no | yes |
SDK2_HUMAN | [view interactions] | High throughput | no | no |
TOP3B_HUMAN | [view interactions] | High throughput | no | no |
SEM4C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
IFM3_HUMAN | [view interactions] | High throughput | no | yes |
SH3B4_HUMAN | [view interactions] | High throughput | no | yes |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
SH3R1_HUMAN | [view interactions] | High throughput | no | yes |
RHOQ_HUMAN | [view interactions] | High throughput | no | no |
SHB_HUMAN | [view interactions] | High throughput | no | yes |
RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHSA2_HUMAN | [view interactions] | High throughput | no | no |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S12A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOF_HUMAN | [view interactions] | High throughput | no | no |
S12A6_HUMAN | [view interactions] | High throughput | no | yes |
RHOU_HUMAN | [view interactions] | High throughput | no | no |
S12A7_HUMAN | [view interactions] | High throughput | no | yes |
RHOH_HUMAN | [view interactions] | High throughput | no | yes |
MOT1_HUMAN | [view interactions] | High throughput | no | no |
TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S19A1_HUMAN | [view interactions] | High throughput | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EAA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DDR1_HUMAN | [view interactions] | High throughput | no | yes |
RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
AAAT_HUMAN | [view interactions] | High throughput | no | no |
BTF3_HUMAN | [view interactions] | High throughput | no | yes |
RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S20A2_HUMAN | [view interactions] | High throughput | no | yes |
PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
RAC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S29A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOC_HUMAN | [view interactions] | High throughput | no | no |
ZNT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PGFRB_HUMAN | [view interactions] | High throughput | no | yes |
RHOD_HUMAN | [view interactions] | High throughput | no | no |
S38A1_HUMAN | [view interactions] | High throughput | no | yes |
SYDE1_HUMAN | [view interactions] | High throughput | no | yes |
RND2_HUMAN | [view interactions] | High throughput | no | no |
S38A2_HUMAN | [view interactions] | High throughput | no | yes |
SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
BPNT1_HUMAN | [view interactions] | High throughput | no | yes |
S39AA_HUMAN | [view interactions] | High throughput | no | no |
IRAK2_HUMAN | [view interactions] | High throughput | no | yes |
S39AE_HUMAN | [view interactions] | High throughput | no | yes |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
S39A6_HUMAN | [view interactions] | High throughput | no | yes |
BLK_HUMAN | [view interactions] | High throughput | no | no |
4F2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARG28_HUMAN | [view interactions] | High throughput | no | yes |
S4A7_HUMAN | [view interactions] | High throughput | no | no |
ARHG5_HUMAN | [view interactions] | High throughput | no | yes |
S6A15_HUMAN | [view interactions] | High throughput | no | yes |
SC6A8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TM1L1_HUMAN | [view interactions] | High throughput | no | yes |
TRAT1_HUMAN | [view interactions] | High throughput | no | no |
XCT_HUMAN | [view interactions] | High throughput | no | no |
ADCK2_HUMAN | [view interactions] | High throughput | no | yes |
CTR2_HUMAN | [view interactions] | High throughput | no | no |
PIM3_HUMAN | [view interactions] | High throughput | no | no |
LAT1_HUMAN | [view interactions] | High throughput | no | yes |
TBCK_HUMAN | [view interactions] | High throughput | no | yes |
SNP23_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HASP_HUMAN | [view interactions] | High throughput | no | yes |
SNP47_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NRBP2_HUMAN | [view interactions] | High throughput | no | yes |
CYTSB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERBB3_HUMAN | [view interactions] | High throughput | no | yes |
SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERBB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STEA3_HUMAN | [view interactions] | High throughput | no | yes |
KS6B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STK10_HUMAN | [view interactions] | High throughput | no | yes |
KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
STXB3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDK4_HUMAN | [view interactions] | High throughput | no | no |
TANC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TB10B_HUMAN | [view interactions] | High throughput | no | no |
TBCD8_HUMAN | [view interactions] | High throughput | no | yes |
TIAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEIP2_HUMAN | [view interactions] | High throughput | no | yes |
TMM51_HUMAN | [view interactions] | High throughput | no | yes |
TOX3_HUMAN | [view interactions] | High throughput | no | yes |
CD37_HUMAN | [view interactions] | High throughput | no | no |
TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TULP3_HUMAN | [view interactions] | High throughput | no | yes |
MAL_HUMAN | [view interactions] | High throughput | no | no |
ITPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UACA_HUMAN | [view interactions] | High throughput | no | yes |
DYLT1_HUMAN | [view interactions] | High throughput | no | no |
RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UNC5B_HUMAN | [view interactions] | High throughput | no | yes |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
REN3B_HUMAN | [view interactions] | High throughput | no | yes |
CK052_HUMAN | [view interactions] | High throughput | no | no |
UBP31_HUMAN | [view interactions] | High throughput | no | yes |
RACK1_HUMAN | [view interactions] | High throughput | no | yes |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
US6NL_HUMAN | [view interactions] | High throughput | no | yes |
KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXAR_HUMAN | [view interactions] | High throughput | no | yes |
UTRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DIRA3_HUMAN | [view interactions] | High throughput | no | yes |
VAMP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ERGI1_HUMAN | [view interactions] | High throughput | no | yes |
VAMP3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LITD1_HUMAN | [view interactions] | High throughput | no | no |
CXD3_HUMAN | [view interactions] | High throughput | no | no |
VANG1_HUMAN | [view interactions] | High throughput | no | no |
CD177_HUMAN | [view interactions] | High throughput | no | no |
LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
VANG2_HUMAN | [view interactions] | High throughput | no | no |
LAMP3_HUMAN | [view interactions] | High throughput | no | no |
WASF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WDR20_HUMAN | [view interactions] | High throughput | no | no |
LMAN1_HUMAN | [view interactions] | High throughput | no | yes |
WDR6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
XPR1_HUMAN | [view interactions] | High throughput | no | yes |
MRP1_HUMAN | [view interactions] | High throughput | no | no |
YKT6_HUMAN | [view interactions] | High throughput | no | yes |
MRP5_HUMAN | [view interactions] | High throughput | no | no |
ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
A2MG_HUMAN | [view interactions] | High throughput | no | yes |
ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZDHC8_HUMAN | [view interactions] | High throughput | no | yes |
PGCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADCY3_HUMAN | [view interactions] | High throughput | no | yes |
SEPT9_HUMAN | [view interactions] | High throughput | no | no |
MARK4_HUMAN | [view interactions] | High throughput | no | yes |
ADCY9_HUMAN | [view interactions] | High throughput | no | yes |
AFAD_HUMAN | [view interactions] | High throughput | no | yes |
ERP44_HUMAN | [view interactions] | High throughput | no | yes |
ADDA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AHNK2_HUMAN | [view interactions] | High throughput | no | yes |
SAP_HUMAN | [view interactions] | High throughput | no | yes |
ADDB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MECP2_HUMAN | [view interactions] | High throughput | no | yes |
ADDG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CARL1_HUMAN | [view interactions] | High throughput | no | yes |
SPRE1_HUMAN | [view interactions] | High throughput | no | yes |
AGRL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
COBL1_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DEN4C_HUMAN | [view interactions] | High throughput | no | yes |
SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
M3K3_HUMAN | [view interactions] | High throughput | no | no |
AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
TRI69_HUMAN | [view interactions] | High throughput | no | no |
AKAP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ESYT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANDR_HUMAN | [view interactions] | High throughput | no | no |
AKT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ITSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GAB1_HUMAN | [view interactions] | High throughput | no | yes |
ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANR26_HUMAN | [view interactions] | High throughput | no | yes |
MILK1_HUMAN | [view interactions] | High throughput | no | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
ANR50_HUMAN | [view interactions] | High throughput | no | no |
MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
ACE2_HUMAN | [view interactions] | High throughput | no | no |
APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MYO6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UHRF2_HUMAN | [view interactions] | High throughput | no | no |
ARAP2_HUMAN | [view interactions] | High throughput | no | no |
NF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFIP5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI63_HUMAN | [view interactions] | High throughput | no | no |
RHG12_HUMAN | [view interactions] | High throughput | no | yes |
SH319_HUMAN | [view interactions] | High throughput | no | no |
TRI55_HUMAN | [view interactions] | High throughput | no | no |
RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNP29_HUMAN | [view interactions] | High throughput | no | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AR13B_HUMAN | [view interactions] | High throughput | no | yes |
TB182_HUMAN | [view interactions] | High throughput | no | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AT133_HUMAN | [view interactions] | High throughput | no | yes |
BOREA_HUMAN | [view interactions] | High throughput | no | yes |
KCNJ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AT1A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DHX33_HUMAN | [view interactions] | High throughput | no | yes |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
AT2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EPHB3_HUMAN | [view interactions] | High throughput | no | yes |
AT2B4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H14_HUMAN | [view interactions] | High throughput | no | yes |
ATP7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INCE_HUMAN | [view interactions] | High throughput | no | no |
BI2L1_HUMAN | [view interactions] | High throughput | no | yes |
IPO5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BASP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LCAP_HUMAN | [view interactions] | High throughput | no | yes |
BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LTV1_HUMAN | [view interactions] | High throughput | no | yes |
CA021_HUMAN | [view interactions] | High throughput | no | yes |
MTA1_HUMAN | [view interactions] | High throughput | no | yes |
C2CD5_HUMAN | [view interactions] | High throughput | no | yes |
MBB1A_HUMAN | [view interactions] | High throughput | no | yes |
CAHD1_HUMAN | [view interactions] | High throughput | no | no |
NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSKI2_HUMAN | [view interactions] | High throughput | no | yes |
PHF2_HUMAN | [view interactions] | High throughput | no | yes |
CBARP_HUMAN | [view interactions] | High throughput | no | no |
PLD1_HUMAN | [view interactions] | High throughput | no | no |
GRDN_HUMAN | [view interactions] | High throughput | no | no |
PLXB2_HUMAN | [view interactions] | High throughput | no | yes |
DAPLE_HUMAN | [view interactions] | High throughput | no | yes |
REXO4_HUMAN | [view interactions] | High throughput | no | yes |
CD99_HUMAN | [view interactions] | High throughput | no | no |
RNH2B_HUMAN | [view interactions] | High throughput | no | yes |
MRCKA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MRCKB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BORG5_HUMAN | [view interactions] | High throughput | no | yes |
TFR1_HUMAN | [view interactions] | High throughput | no | yes |
BORG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BRD2_HUMAN | [view interactions] | High throughput | no | yes |
CDCA3_HUMAN | [view interactions] | High throughput | no | no |
DDX18_HUMAN | [view interactions] | High throughput | no | yes |
CDK16_HUMAN | [view interactions] | High throughput | no | yes |
DDX49_HUMAN | [view interactions] | High throughput | no | no |
CEP89_HUMAN | [view interactions] | High throughput | no | no |
DDX55_HUMAN | [view interactions] | High throughput | no | yes |
CNNM3_HUMAN | [view interactions] | High throughput | no | yes |
EXOS9_HUMAN | [view interactions] | High throughput | no | yes |
ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FUBP3_HUMAN | [view interactions] | High throughput | no | yes |
CPNE8_HUMAN | [view interactions] | High throughput | no | yes |
H2AY_HUMAN | [view interactions] | High throughput | no | yes |
BLNK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KC1G3_HUMAN | [view interactions] | High throughput | no | yes |
MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOC2L_HUMAN | [view interactions] | High throughput | no | yes |
CTNL1_HUMAN | [view interactions] | High throughput | no | no |
NSD2_HUMAN | [view interactions] | High throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PESC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP97_HUMAN | [view interactions] | High throughput | no | yes |
CTND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PHC3_HUMAN | [view interactions] | High throughput | no | yes |
CP110_HUMAN | [view interactions] | High throughput | no | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHF8_HUMAN | [view interactions] | High throughput | no | yes |
DAB2P_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PHIP_HUMAN | [view interactions] | High throughput | no | yes |
DEP1B_HUMAN | [view interactions] | High throughput | no | yes |
RGAP1_HUMAN | [view interactions] | High throughput | no | no |
GP1BB_HUMAN | [view interactions] | High throughput | no | no |
DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DMD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBM28_HUMAN | [view interactions] | High throughput | no | yes |
DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RBM34_HUMAN | [view interactions] | High throughput | no | yes |
SVIL_HUMAN | [view interactions] | High throughput | no | yes |
DSC2_HUMAN | [view interactions] | High throughput | no | no |
RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAN2_HUMAN | [view interactions] | High throughput | no | no |
DSG2_HUMAN | [view interactions] | High throughput | no | no |
RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SH21A_HUMAN | [view interactions] | High throughput | no | no |
DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RN180_HUMAN | [view interactions] | High throughput | no | yes |
DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KHDR2_HUMAN | [view interactions] | High throughput | no | yes |
DZIP1_HUMAN | [view interactions] | High throughput | no | yes |
RRP15_HUMAN | [view interactions] | High throughput | no | yes |
LNP1_HUMAN | [view interactions] | High throughput | no | no |
EFNB1_HUMAN | [view interactions] | High throughput | no | yes |
SMCA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P55G_HUMAN | [view interactions] | High throughput | no | yes |
EFNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TOP2B_HUMAN | [view interactions] | High throughput | no | yes |
PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFR3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSR1_HUMAN | [view interactions] | High throughput | no | no |
SH2D3_HUMAN | [view interactions] | High throughput | no | no |
EFR3B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HBS1L_HUMAN | [view interactions] | High throughput | no | yes |
EPB41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SH24A_HUMAN | [view interactions] | High throughput | no | no |
E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFA91_HUMAN | [view interactions] | High throughput | no | no |
E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DPP4_HUMAN | [view interactions] | High throughput | no | no |
DTX3_HUMAN | [view interactions] | High throughput | no | yes |
E41LB_HUMAN | [view interactions] | High throughput | no | yes |
TM11B_HUMAN | [view interactions] | High throughput | no | no |
HXC4_HUMAN | [view interactions] | High throughput | no | no |
E41L5_HUMAN | [view interactions] | High throughput | no | no |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CBX6_HUMAN | [view interactions] | High throughput | no | yes |
EPHA2_HUMAN | [view interactions] | High throughput | no | no |
PP2AB_HUMAN | [view interactions] | Computational | no | yes |
2A5B_HUMAN | [view interactions] | Computational | no | yes |
MK08_HUMAN | [view interactions] | Computational | no | yes |
SLAP1_HUMAN | [view interactions] | Computational | no | yes |
EGF_HUMAN | [view interactions] | Computational | no | no |
2AAB_HUMAN | [view interactions] | Computational | no | yes |
ELMO1_HUMAN | [view interactions] | Computational | no | no |
CXCR1_HUMAN | [view interactions] | Computational | no | yes |
BCR_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CDN1A_HUMAN | [view interactions] | Computational | no | no |
CSF2R_HUMAN | [view interactions] | Computational | no | no |
DAPP1_HUMAN | [view interactions] | Computational | no | yes |
JUN_HUMAN | [view interactions] | Computational | no | yes |
FER_HUMAN | [view interactions] | Computational | no | yes |
CLC6A_HUMAN | [view interactions] | Computational | no | no |
GRB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FYN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
ZAP70_HUMAN | [view interactions] | Computational | no | no |
NFKB1_HUMAN | [view interactions] | Computational | no | yes |
ABL1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NEDD4_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
IL8_HUMAN | [view interactions] | Computational | no | no |
CXCR4_HUMAN | [view interactions] | Computational | no | no |
LPAR3_HUMAN | [view interactions] | Computational | no | no |
STAT1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TDGF1_HUMAN | [view interactions] | Computational | no | no |
PDGFB_HUMAN | [view interactions] | Computational | no | yes |
IL5RA_HUMAN | [view interactions] | Computational | no | no |
ITAM_HUMAN | [view interactions] | Computational | no | no |
FCERG_HUMAN | [view interactions] | Computational | no | no |
MK14_HUMAN | [view interactions] | Computational | no | yes |
S1PR1_HUMAN | [view interactions] | Computational | no | no |
KPCT_HUMAN | [view interactions] | Computational | no | no |
CD28_HUMAN | [view interactions] | Computational | no | no |
TLR2_HUMAN | [view interactions] | Computational | no | no |
PK3CB_HUMAN | [view interactions] | Computational | no | yes |
FOS_HUMAN | [view interactions] | Computational | no | yes |
PTN11_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
FCERA_HUMAN | [view interactions] | Computational | no | yes |
BCL6_HUMAN | [view interactions] | Computational | no | no |
PI3R6_HUMAN | [view interactions] | Computational | no | yes |
CSF2_HUMAN | [view interactions] | Computational | no | no |
CD3Z_HUMAN | [view interactions] | Computational | no | no |
NTAL_HUMAN | [view interactions] | Computational | no | no |
STA5B_HUMAN | [view interactions] | Computational | no | yes |
CD3G_HUMAN | [view interactions] | Computational | no | no |
LPAR1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PP2AA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CCND1_HUMAN | [view interactions] | Computational | no | yes |
2A5E_HUMAN | [view interactions] | Computational | no | yes |
EFNA1_HUMAN | [view interactions] | Computational | no | no |
WIPF1_HUMAN | [view interactions] | Computational | no | no |
GNAI2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GPC1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
2AAA_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CCND3_HUMAN | [view interactions] | Computational | no | no |
2A5G_HUMAN | [view interactions] | Computational | no | yes |
PAXI_HUMAN | [view interactions] | Computational | no | yes |
CSK_HUMAN | [view interactions] | Computational | no | yes |
CD79B_HUMAN | [view interactions] | Computational | no | no |
CDN1C_HUMAN | [view interactions] | Computational | no | yes |
MTG1_HUMAN | [view interactions] | Computational | no | yes |
CDK6_HUMAN | [view interactions] | Computational | no | yes |
2A5A_HUMAN | [view interactions] | Computational | no | yes |
PLCG1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GRIA2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EPO_HUMAN | [view interactions] | Computational | no | no |
GPIX_HUMAN | [view interactions] | Computational | no | no |
TLR4_HUMAN | [view interactions] | Computational | no | yes |
IBTK_HUMAN | [view interactions] | Computational | no | yes |
PA24A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
TRPV6_HUMAN | [view interactions] | Computational | no | no |
VAV2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
NGEF_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
3BP5_HUMAN | [view interactions] | Computational | no | yes |
PK3CA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
EFNA5_HUMAN | [view interactions] | Computational | no | yes |
VAV_HUMAN | [view interactions] | Computational | no | no |
LPAR2_HUMAN | [view interactions] | Computational | no | yes |
KPCA_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CLC4E_HUMAN | [view interactions] | Computational | no | no |
PK3CD_HUMAN | [view interactions] | Computational | no | no |
ARRB1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ARRB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
EPHB2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
GPV_HUMAN | [view interactions] | Computational | no | no |
MK11_HUMAN | [view interactions] | Computational | no | yes |
STA5A_HUMAN | [view interactions] | Computational | no | no |
KPCG_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KLRG1_HUMAN | [view interactions] | Computational | no | no |
EPHB1_HUMAN | [view interactions] | Computational | no | no |
FCGR1_HUMAN | [view interactions] | Computational | no | no |
EPHA1_HUMAN | [view interactions] | Computational | no | yes |
GRIA1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RASA1_HUMAN | [view interactions] | Computational | no | yes |
ITK_HUMAN | [view interactions] | Computational | no | no |
LAT_HUMAN | [view interactions] | Computational | no | no |
CCND2_HUMAN | [view interactions] | Computational | no | yes |
IL5_HUMAN | [view interactions] | Computational | no | no |
GRIA3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |