Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

E41L2_HUMAN

Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in E41L2_HUMAN
GO:0043168 anion binding 30.3030 4 no
GO:0032555 purine ribonucleotide binding 29.2929 4 no
GO:0000166 nucleotide binding 29.2929 4 no
GO:0017076 purine nucleotide binding 29.2929 5 no
GO:0035639 purine ribonucleoside triphosphate binding 28.2828 4 no
GO:0019900 kinase binding 27.2727 4 no
GO:0003723 RNA binding 24.2424 4 no
GO:0019901 protein kinase binding 24.2424 5 no
GO:0043169 cation binding 21.2121 4 no
GO:0046872 metal ion binding 21.2121 5 no
GO:0032559 adenyl ribonucleotide binding 20.2020 5 no
GO:0030554 adenyl nucleotide binding 20.2020 6 no
GO:0003779 actin binding 13.1313 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in E41L2_HUMAN
GO:0048522 positive regulation of cellular process 63.6364 4 yes
GO:0048523 negative regulation of cellular process 57.5758 4 no
GO:0060255 regulation of macromolecule metabolic process 57.5758 4 no
GO:0031323 regulation of cellular metabolic process 56.5657 4 no
GO:0080090 regulation of primary metabolic process 52.5253 4 no
GO:0010646 regulation of cell communication 49.4949 4 no
GO:0009889 regulation of biosynthetic process 45.4545 4 no
GO:0009893 positive regulation of metabolic process 43.4343 4 no
GO:0010556 regulation of macromolecule biosynthetic process 43.4343 5 no
GO:0031326 regulation of cellular biosynthetic process 43.4343 5 no
GO:0006996 organelle organization 40.4040 4 yes
GO:0009892 negative regulation of metabolic process 40.4040 4 no
GO:0009966 regulation of signal transduction 40.4040 4 no
GO:0010468 regulation of gene expression 40.4040 6 no
GO:0010604 positive regulation of macromolecule metabolic process 40.4040 5 no
GO:0051128 regulation of cellular component organization 40.4040 4 no
GO:0031325 positive regulation of cellular metabolic process 38.3838 5 no
GO:0051246 regulation of protein metabolic process 38.3838 5 no
GO:0010605 negative regulation of macromolecule metabolic process 36.3636 5 no
GO:0008104 protein localization 35.3535 4 no
GO:0022607 cellular component assembly 34.3434 4 no
GO:0031399 regulation of protein modification process 33.3333 6 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0051049 regulation of transport 32.3232 4 no
GO:0048584 positive regulation of response to stimulus 30.3030 4 no
GO:1902531 regulation of intracellular signal transduction 30.3030 5 no
GO:0009891 positive regulation of biosynthetic process 29.2929 5 no
GO:0060341 regulation of cellular localization 28.2828 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 28.2828 5 no
GO:0019220 regulation of phosphate metabolic process 28.2828 6 no
GO:0031328 positive regulation of cellular biosynthetic process 28.2828 6 no
GO:0051174 regulation of phosphorus metabolic process 28.2828 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 27.2727 6 no
GO:0051247 positive regulation of protein metabolic process 27.2727 6 no
GO:0010647 positive regulation of cell communication 25.2525 5 no
GO:0023056 positive regulation of signaling 25.2525 4 no
GO:0042325 regulation of phosphorylation 25.2525 7 no
GO:0051252 regulation of RNA metabolic process 25.2525 5 no
GO:0001932 regulation of protein phosphorylation 24.2424 7 no
GO:0048585 negative regulation of response to stimulus 24.2424 4 no
GO:0071702 organic substance transport 24.2424 4 no
GO:0071705 nitrogen compound transport 24.2424 4 no
GO:0007010 cytoskeleton organization 23.2323 5 yes
GO:0032880 regulation of protein localization 23.2323 5 yes
GO:0031401 positive regulation of protein modification process 23.2323 7 no
GO:0042981 regulation of apoptotic process 23.2323 5 no
GO:0043067 regulation of programmed cell death 23.2323 4 no
GO:0051248 negative regulation of protein metabolic process 23.2323 6 no
GO:0006355 regulation of DNA-templated transcription 22.2222 7 no
GO:0010648 negative regulation of cell communication 22.2222 5 no
GO:0023057 negative regulation of signaling 22.2222 4 no
GO:2001141 regulation of RNA biosynthetic process 22.2222 6 no
GO:0009890 negative regulation of biosynthetic process 22.2222 5 no
GO:0044087 regulation of cellular component biogenesis 21.2121 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 21.2121 6 no
GO:0031327 negative regulation of cellular biosynthetic process 21.2121 6 no
GO:0009967 positive regulation of signal transduction 20.2020 5 no
GO:0043412 macromolecule modification 20.2020 4 no
GO:0141124 intracellular signaling cassette 20.2020 4 no
GO:1903829 positive regulation of protein localization 17.1717 5 yes
GO:1904375 regulation of protein localization to cell periphery 8.0808 6 yes
GO:0030865 cortical cytoskeleton organization 7.0707 6 yes
GO:0030866 cortical actin cytoskeleton organization 6.0606 4 yes
GO:0031032 actomyosin structure organization 6.0606 4 yes
GO:1904377 positive regulation of protein localization to cell periphery 5.0505 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
NUMA1_HUMAN [view interactions] Low throughput no yes
FCGR1_HUMAN [view interactions] Low throughput no no
PALS2_HUMAN [view interactions] Low throughput no yes
FKBP2_HUMAN [view interactions] Low throughput no yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTH1R_HUMAN [view interactions] Low throughput no no
GRM1_HUMAN [view entry] [view interactions] Low throughput yes yes
KT222_HUMAN [view interactions] High throughput no no
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
DDAH1_HUMAN [view entry] [view interactions] High throughput yes no
SPF27_HUMAN [view interactions] High throughput no yes
SRS10_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
FA83G_HUMAN [view interactions] High throughput no no
KLH15_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
BRD9_HUMAN [view interactions] High throughput no yes
CSK22_HUMAN [view entry] [view interactions] High throughput yes no
SRP09_HUMAN [view interactions] High throughput no no
TLS1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
BAP1_HUMAN [view interactions] High throughput no yes
CLD4_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
PARPT_HUMAN [view interactions] High throughput no no
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
TRI67_HUMAN [view interactions] High throughput no no
TRI33_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP48_HUMAN [view interactions] High throughput no yes
UBE2O_HUMAN [view interactions] High throughput no yes
MOB3C_HUMAN [view interactions] High throughput no no
MIDN_HUMAN [view interactions] High throughput no no
ANLN_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
CALD1_HUMAN [view entry] [view interactions] High throughput yes no
CSN4_HUMAN [view interactions] High throughput no yes
CSK21_HUMAN [view entry] [view interactions] High throughput yes yes
DCAF8_HUMAN [view interactions] High throughput no yes
MEP50_HUMAN [view interactions] High throughput no yes
CADM1_HUMAN [view entry] [view interactions] High throughput yes no
CSKP_HUMAN [view entry] [view interactions] High throughput yes yes
CSN6_HUMAN [view interactions] High throughput no yes
DLG1_HUMAN [view entry] [view interactions] High throughput yes yes
DPY30_HUMAN [view interactions] High throughput no yes
PI42C_HUMAN [view interactions] High throughput no yes
AP3S1_HUMAN [view entry] [view interactions] High throughput yes no
CSN2_HUMAN [view interactions] High throughput no yes
CSN3_HUMAN [view entry] [view interactions] High throughput yes yes
CSN8_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
SCOC_HUMAN [view interactions] High throughput no yes
TMOD1_HUMAN [view entry] [view interactions] High throughput yes yes
BASP1_HUMAN [view entry] [view interactions] High throughput yes yes
CSN7A_HUMAN [view interactions] High throughput no yes
GCYB1_HUMAN [view interactions] High throughput no yes
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
SMCA5_HUMAN [view interactions] High throughput no yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
RU17_HUMAN [view interactions] High throughput no yes
TPR_HUMAN [view interactions] High throughput no yes
SYDC_HUMAN [view interactions] High throughput no yes
HSP76_HUMAN [view entry] [view interactions] High throughput yes yes
PLCG1_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
CLIP1_HUMAN [view entry] [view interactions] High throughput yes yes
RPB2_HUMAN [view interactions] High throughput no yes
HS71L_HUMAN [view entry] [view interactions] High throughput yes no
CTNA1_HUMAN [view entry] [view interactions] High throughput yes yes
RBMX_HUMAN [view entry] [view interactions] High throughput yes yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
RAGP1_HUMAN [view entry] [view interactions] High throughput yes yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
RBP2_HUMAN [view interactions] High throughput no yes
SMCA4_HUMAN [view interactions] High throughput no yes
ACLY_HUMAN [view entry] [view interactions] High throughput yes yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
DYL1_HUMAN [view entry] [view interactions] High throughput yes no
TBB4B_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
FKBP4_HUMAN [view entry] [view interactions] High throughput yes yes
PTN11_HUMAN [view entry] [view interactions] High throughput yes yes
RHG01_HUMAN [view entry] [view interactions] High throughput yes yes
BPTF_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
CSN1_HUMAN [view interactions] High throughput no no
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
RCN1_HUMAN [view interactions] High throughput no yes
RABL6_HUMAN [view interactions] High throughput no yes
CAVN1_HUMAN [view interactions] High throughput no no
H32_HUMAN [view interactions] High throughput no yes
FNBP4_HUMAN [view interactions] High throughput no yes
ARI1B_HUMAN [view interactions] High throughput no yes
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
CNDP2_HUMAN [view entry] [view interactions] High throughput yes yes
DOCK7_HUMAN [view entry] [view interactions] High throughput yes no
FNBP1_HUMAN [view interactions] High throughput no yes
TBA1C_HUMAN [view interactions] High throughput no yes
CSN7B_HUMAN [view interactions] High throughput no yes
RENT2_HUMAN [view interactions] High throughput no no
WDR6_HUMAN [view entry] [view interactions] High throughput yes yes
SPN90_HUMAN [view entry] [view interactions] High throughput yes no
RALY_HUMAN [view interactions] High throughput no yes
PACN2_HUMAN [view entry] [view interactions] High throughput yes no
TIM_HUMAN [view interactions] High throughput no yes
NUDC_HUMAN [view interactions] High throughput no yes
TLN1_HUMAN [view entry] [view interactions] High throughput yes no
DCAF1_HUMAN [view interactions] High throughput no yes
NUP35_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
GBF1_HUMAN [view interactions] High throughput no yes
DCA15_HUMAN [view interactions] High throughput no no
RHBL4_HUMAN [view interactions] High throughput no no
RHDF2_HUMAN [view interactions] High throughput no yes
PLCG2_HUMAN [view interactions] High throughput no yes
SEC62_HUMAN [view interactions] High throughput no yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
RN183_HUMAN [view interactions] High throughput no no
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
LEG9_HUMAN [view interactions] High throughput no yes
KIBRA_HUMAN [view entry] [view interactions] High throughput yes yes
DNJC5_HUMAN [view interactions] High throughput no yes
LIN7A_HUMAN [view entry] [view interactions] High throughput yes yes
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
KLC4_HUMAN [view interactions] High throughput no yes
CK052_HUMAN [view interactions] High throughput no no
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
CAV1_HUMAN [view interactions] High throughput no no
PAX6_HUMAN [view interactions] High throughput no no
DIRA3_HUMAN [view interactions] High throughput no yes
FAN_HUMAN [view interactions] High throughput no yes
RCAS1_HUMAN [view interactions] High throughput no yes
WASH1_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
WRP73_HUMAN [view interactions] High throughput no no
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
KSR1_HUMAN [view interactions] High throughput no yes
LAMP1_HUMAN [view entry] [view interactions] High throughput yes yes
CXB7_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
AP3B1_HUMAN [view entry] [view interactions] High throughput yes yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
SET1A_HUMAN [view interactions] High throughput no yes
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
POTEI_HUMAN [view interactions] High throughput no no
OCLN_HUMAN [view interactions] High throughput no no
AF9_HUMAN [view interactions] High throughput no yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
ICLN_HUMAN [view interactions] High throughput no yes
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
STX6_HUMAN [view interactions] High throughput no yes
ENL_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
PPIG_HUMAN [view interactions] High throughput no yes
ZFPL1_HUMAN [view interactions] High throughput no yes
NKAP_HUMAN [view interactions] High throughput no yes
NAA40_HUMAN [view interactions] High throughput no no
PININ_HUMAN [view interactions] High throughput no yes
CACO2_HUMAN [view interactions] High throughput no yes
CWC22_HUMAN [view interactions] High throughput no yes
TAXB1_HUMAN [view interactions] High throughput no yes
GPTC8_HUMAN [view interactions] High throughput no yes
TOLIP_HUMAN [view entry] [view interactions] High throughput yes yes
ACINU_HUMAN [view interactions] High throughput no yes
UFO_HUMAN [view interactions] High throughput no no
SRRM2_HUMAN [view interactions] High throughput no yes
PML_HUMAN [view interactions] High throughput no yes
MLF1_HUMAN [view entry] [view interactions] High throughput yes yes
PHLP1_HUMAN [view interactions] High throughput no yes
DDAH2_HUMAN [view interactions] High throughput no yes
ARL4C_HUMAN [view interactions] High throughput no yes
WDR59_HUMAN [view interactions] High throughput no yes
ARL5A_HUMAN [view interactions] High throughput no yes
LRRK2_HUMAN [view interactions] High throughput no yes
AR13B_HUMAN [view interactions] High throughput no yes
KAP0_HUMAN [view entry] [view interactions] High throughput yes yes
ARL14_HUMAN [view interactions] High throughput no no
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
ARL15_HUMAN [view interactions] High throughput no yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
CNTP2_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
CCNF_HUMAN [view interactions] High throughput no no
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
RICTR_HUMAN [view interactions] High throughput no yes
SNR40_HUMAN [view interactions] High throughput no yes
SND1_HUMAN [view entry] [view interactions] High throughput yes yes
ARI5B_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
PRC1_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
ZN736_HUMAN [view interactions] High throughput no no
RFA3_HUMAN [view interactions] High throughput no yes
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
RFA4_HUMAN [view interactions] High throughput no yes
MUC18_HUMAN [view interactions] High throughput no yes
PIM3_HUMAN [view interactions] High throughput no no
CAMKV_HUMAN [view entry] [view interactions] High throughput yes yes
TBCK_HUMAN [view interactions] High throughput no yes
HASP_HUMAN [view interactions] High throughput no yes
NUAK2_HUMAN [view interactions] High throughput no yes
M3K2_HUMAN [view interactions] High throughput no yes
SRPK2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
PRIO_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA7_HUMAN [view interactions] High throughput no yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
AGAP2_HUMAN [view entry] [view interactions] High throughput yes yes
RD3_HUMAN [view interactions] High throughput no no
RYBP_HUMAN [view interactions] High throughput no no
WNK1_HUMAN [view entry] [view interactions] High throughput yes no
CSN5_HUMAN [view interactions] High throughput no yes
ESR1_HUMAN [view interactions] High throughput no no
CCNT1_HUMAN [view interactions] High throughput no yes
CCD61_HUMAN [view interactions] High throughput no yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
ATX1L_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
SIR7_HUMAN [view interactions] High throughput no yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
CCDC8_HUMAN [view interactions] High throughput no yes
ABCE1_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
E41L1_HUMAN [view entry] [view interactions] High throughput yes yes
RNPS1_HUMAN [view interactions] High throughput no yes
ZRAB2_HUMAN [view interactions] High throughput no yes
CLK2_HUMAN [view interactions] High throughput no yes
SRP68_HUMAN [view interactions] High throughput no yes
CP2S1_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
SPDLY_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
UBE3A_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
WDR76_HUMAN [view interactions] High throughput no no
H4_HUMAN [view interactions] High throughput no yes
H2A1B_HUMAN [view interactions] High throughput no yes
UBP14_HUMAN [view entry] [view interactions] High throughput yes yes
PP1G_HUMAN [view entry] [view interactions] High throughput yes yes
TIA1_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
DOC11_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
NUPR1_HUMAN [view interactions] High throughput no no
CIC_HUMAN [view interactions] High throughput no yes
DTX3L_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
FNDC5_HUMAN [view interactions] High throughput no no
DDX56_HUMAN [view interactions] High throughput no yes
MFAP1_HUMAN [view interactions] High throughput no yes
RB15B_HUMAN [view interactions] High throughput no yes
DCA13_HUMAN [view interactions] High throughput no yes
POP1_HUMAN [view interactions] High throughput no no
NSRP1_HUMAN [view interactions] High throughput no yes
HXA5_HUMAN [view interactions] High throughput no no
MEPCE_HUMAN [view interactions] High throughput no yes
PR40A_HUMAN [view interactions] High throughput no no
SRC8_HUMAN [view entry] [view interactions] High throughput yes yes
ATX2L_HUMAN [view interactions] High throughput no no
AMRP_HUMAN [view interactions] High throughput no yes
RRP1B_HUMAN [view interactions] High throughput no yes
MMTA2_HUMAN [view interactions] High throughput no yes
PP1RA_HUMAN [view interactions] High throughput no yes
TOX4_HUMAN [view interactions] High throughput no yes
DDX42_HUMAN [view interactions] High throughput no yes
MECP2_HUMAN [view interactions] High throughput no yes
NUFP2_HUMAN [view interactions] High throughput no no
FA76B_HUMAN [view interactions] High throughput no no
RBM25_HUMAN [view interactions] High throughput no yes
KC1D_HUMAN [view entry] [view interactions] High throughput yes yes
SNIP1_HUMAN [view interactions] High throughput no no
CBX4_HUMAN [view interactions] High throughput no yes
CPSF7_HUMAN [view interactions] High throughput no yes
TAF2_HUMAN [view interactions] High throughput no no
APR_HUMAN [view interactions] High throughput no yes
P53_HUMAN [view interactions] High throughput no no
CERS2_HUMAN [view interactions] High throughput no no
JMJD6_HUMAN [view interactions] High throughput no yes