DOCK7_HUMAN
Evidence for PS localization
Functions
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 Ser-15 phosphorylation during axon formation and consequently for neuronal polarization (PubMed). As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton (PubMed). Has a role in pigmentation . Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 . [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI003072 | DOC_MAPK_JIP1_4 | DOC | 885 | 891 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DOCK7_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 37.0968 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 32.2581 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 32.2581 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 25.8065 | 5 | no |
| GO:0003723 | RNA binding | 22.5806 | 4 | no |
| GO:0005524 | ATP binding | 20.9677 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.9677 | 5 | no |
| GO:0031267 | small GTPase binding | 8.0645 | 5 | yes |
| GO:0051020 | GTPase binding | 8.0645 | 4 | yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | 3.2258 | 5 | yes |
| GO:0030695 | GTPase regulator activity | 3.2258 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DOCK7_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 72.5806 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 69.3548 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 69.3548 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 66.1290 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 62.9032 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 62.9032 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 58.0645 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 54.8387 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 54.8387 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.8387 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 51.6129 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 48.3871 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 48.3871 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 46.7742 | 4 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 45.1613 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 43.5484 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 43.5484 | 6 | yes |
| GO:0010468 | regulation of gene expression | 43.5484 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 41.9355 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 40.3226 | 6 | yes |
| GO:0051049 | regulation of transport | 40.3226 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 38.7097 | 6 | yes |
| GO:0051174 | regulation of phosphorus metabolic process | 38.7097 | 5 | yes |
| GO:0006996 | organelle organization | 37.0968 | 4 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 37.0968 | 6 | no |
| GO:0008104 | protein localization | 37.0968 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 37.0968 | 5 | no |
| GO:0022607 | cellular component assembly | 35.4839 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 33.8710 | 7 | yes |
| GO:0031401 | positive regulation of protein modification process | 32.2581 | 7 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 32.2581 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 30.6452 | 7 | yes |
| GO:0010562 | positive regulation of phosphorus metabolic process | 30.6452 | 6 | yes |
| GO:0030030 | cell projection organization | 30.6452 | 4 | yes |
| GO:0045937 | positive regulation of phosphate metabolic process | 30.6452 | 7 | yes |
| GO:0009889 | regulation of biosynthetic process | 30.6452 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.6452 | 5 | no |
| GO:0071702 | organic substance transport | 30.6452 | 4 | no |
| GO:0042327 | positive regulation of phosphorylation | 29.0323 | 8 | yes |
| GO:0031344 | regulation of cell projection organization | 29.0323 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.0323 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 29.0323 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 29.0323 | 5 | no |
| GO:0071705 | nitrogen compound transport | 29.0323 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 29.0323 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 27.4194 | 4 | yes |
| GO:0036211 | protein modification process | 27.4194 | 4 | no |
| GO:0043412 | macromolecule modification | 27.4194 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 27.4194 | 5 | no |
| GO:0051050 | positive regulation of transport | 27.4194 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 27.4194 | 5 | no |
| GO:0051338 | regulation of transferase activity | 27.4194 | 4 | no |
| GO:0001934 | positive regulation of protein phosphorylation | 25.8065 | 8 | yes |
| GO:0120036 | plasma membrane bounded cell projection organization | 25.8065 | 5 | yes |
| GO:0009894 | regulation of catabolic process | 25.8065 | 4 | no |
| GO:0033043 | regulation of organelle organization | 25.8065 | 5 | no |
| GO:0023056 | positive regulation of signaling | 25.8065 | 4 | no |
| GO:0010941 | regulation of cell death | 25.8065 | 4 | no |
| GO:0007010 | cytoskeleton organization | 24.1935 | 5 | yes |
| GO:0060341 | regulation of cellular localization | 24.1935 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.1935 | 5 | no |
| GO:0042981 | regulation of apoptotic process | 24.1935 | 6 | no |
| GO:0043067 | regulation of programmed cell death | 24.1935 | 5 | no |
| GO:0043549 | regulation of kinase activity | 24.1935 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.5806 | 5 | no |
| GO:0043269 | regulation of ion transport | 22.5806 | 5 | no |
| GO:0015031 | protein transport | 22.5806 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 22.5806 | 4 | no |
| GO:0010648 | negative regulation of cell communication | 22.5806 | 5 | no |
| GO:0023057 | negative regulation of signaling | 22.5806 | 4 | no |
| GO:0030162 | regulation of proteolysis | 22.5806 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 22.5806 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 22.5806 | 4 | no |
| GO:0051493 | regulation of cytoskeleton organization | 20.9677 | 6 | no |
| GO:0009967 | positive regulation of signal transduction | 20.9677 | 5 | no |
| GO:0034762 | regulation of transmembrane transport | 20.9677 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 20.9677 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 20.9677 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 20.9677 | 6 | no |
| GO:0009968 | negative regulation of signal transduction | 20.9677 | 5 | no |
| GO:0051129 | negative regulation of cellular component organization | 20.9677 | 5 | no |
| GO:0080134 | regulation of response to stress | 20.9677 | 4 | no |
| GO:0045859 | regulation of protein kinase activity | 20.9677 | 6 | no |
| GO:0045595 | regulation of cell differentiation | 17.7419 | 4 | yes |
| GO:0030334 | regulation of cell migration | 16.1290 | 5 | yes |
| GO:0051336 | regulation of hydrolase activity | 16.1290 | 4 | yes |
| GO:0051345 | positive regulation of hydrolase activity | 16.1290 | 5 | yes |
| GO:2000145 | regulation of cell motility | 16.1290 | 4 | yes |
| GO:0030335 | positive regulation of cell migration | 12.9032 | 6 | yes |
| GO:0031175 | neuron projection development | 12.9032 | 6 | yes |
| GO:0040017 | positive regulation of locomotion | 12.9032 | 4 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 12.9032 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 12.9032 | 4 | yes |
| GO:2000147 | positive regulation of cell motility | 12.9032 | 5 | yes |
| GO:0007264 | small GTPase mediated signal transduction | 11.2903 | 4 | yes |
| GO:0060284 | regulation of cell development | 11.2903 | 5 | yes |
| GO:0032990 | cell part morphogenesis | 9.6774 | 4 | yes |
| GO:0048812 | neuron projection morphogenesis | 9.6774 | 7 | yes |
| GO:0048858 | cell projection morphogenesis | 9.6774 | 5 | yes |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 9.6774 | 6 | yes |
| GO:0050767 | regulation of neurogenesis | 8.0645 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 8.0645 | 5 | yes |
| GO:0007409 | axonogenesis | 6.4516 | 8 | yes |
| GO:0033135 | regulation of peptidyl-serine phosphorylation | 4.8387 | 8 | yes |
| GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 4.8387 | 9 | yes |
| GO:0043087 | regulation of GTPase activity | 4.8387 | 5 | yes |
| GO:0043547 | positive regulation of GTPase activity | 4.8387 | 6 | yes |
| GO:0007097 | nuclear migration | 3.2258 | 4 | yes |
| GO:0090630 | activation of GTPase activity | 3.2258 | 7 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in DOCK7_HUMAN |
|---|---|---|---|---|
| DOID:0050155 | sensory system disease | 3.2258 | 3 | no |
| DOID:0050563 | nonsyndromic deafness | 3.2258 | 5 | no |
| DOID:0050564 | autosomal dominant nonsyndromic deafness | 3.2258 | 6 | no |
| DOID:2742 | auditory system disease | 3.2258 | 4 | no |
| DOID:0050700 | cardiomyopathy | 3.2258 | 4 | no |
| DOID:0060036 | intrinsic cardiomyopathy | 3.2258 | 5 | no |
| DOID:114 | heart disease | 3.2258 | 3 | no |
| DOID:2843 | long QT syndrome | 3.2258 | 6 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ERBB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CDC42_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERBB3_HUMAN | [view interactions] | Low throughput | no | yes |
| NBEL2_HUMAN | [view interactions] | Low throughput | no | no |
| MYO6_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NOD2_HUMAN | [view interactions] | Low throughput | no | yes |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
| ARPC3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPR18_HUMAN | [view interactions] | High throughput | no | no |
| SKAP1_HUMAN | [view interactions] | High throughput | no | no |
| PCAT1_HUMAN | [view interactions] | High throughput | no | yes |
| PE2R3_HUMAN | [view interactions] | High throughput | no | no |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| IF16_HUMAN | [view interactions] | High throughput | no | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NRIP3_HUMAN | [view interactions] | High throughput | no | no |
| OSTM1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS26_HUMAN | [view interactions] | High throughput | no | yes |
| MTMR7_HUMAN | [view interactions] | High throughput | no | no |
| AVIL_HUMAN | [view interactions] | High throughput | no | no |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN785_HUMAN | [view interactions] | High throughput | no | no |
| TGM5_HUMAN | [view interactions] | High throughput | no | no |
| KPRB_HUMAN | [view interactions] | High throughput | no | yes |
| IRF3_HUMAN | [view interactions] | High throughput | no | yes |
| LEG7_HUMAN | [view interactions] | High throughput | no | no |
| KLDC9_HUMAN | [view interactions] | High throughput | no | no |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| HIF1N_HUMAN | [view interactions] | High throughput | no | yes |
| TNIP2_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| PPT1_HUMAN | [view interactions] | High throughput | no | yes |
| NEMO_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| RHG30_HUMAN | [view interactions] | High throughput | no | no |
| API5_HUMAN | [view interactions] | High throughput | no | no |
| PDIA4_HUMAN | [view interactions] | High throughput | no | yes |
| GLU2B_HUMAN | [view interactions] | High throughput | no | yes |
| RBBP7_HUMAN | [view interactions] | High throughput | no | yes |
| UBA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRC31_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KIF23_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| BAG5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOSD1_HUMAN | [view interactions] | High throughput | no | no |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S100P_HUMAN | [view interactions] | High throughput | no | no |
| CAN12_HUMAN | [view interactions] | High throughput | no | no |
| PSME1_HUMAN | [view interactions] | High throughput | no | yes |
| RBX1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ISM2_HUMAN | [view interactions] | High throughput | no | no |
| CAN2_HUMAN | [view interactions] | High throughput | no | no |
| CCNB1_HUMAN | [view interactions] | High throughput | no | no |
| TP4A3_HUMAN | [view interactions] | High throughput | no | no |
| MALL_HUMAN | [view interactions] | High throughput | no | no |
| CX001_HUMAN | [view interactions] | High throughput | no | no |
| TCPQM_HUMAN | [view interactions] | High throughput | no | no |
| UBXN6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOLH1_HUMAN | [view interactions] | High throughput | no | no |
| ST1C4_HUMAN | [view interactions] | High throughput | no | no |
| D2HDH_HUMAN | [view interactions] | High throughput | no | no |
| HDHD1_HUMAN | [view interactions] | High throughput | no | yes |
| CAN10_HUMAN | [view interactions] | High throughput | no | yes |
| ERLEC_HUMAN | [view interactions] | High throughput | no | yes |
| EFMT3_HUMAN | [view interactions] | High throughput | no | no |
| CIA2A_HUMAN | [view interactions] | High throughput | no | yes |
| CIB2_HUMAN | [view interactions] | High throughput | no | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MP2K2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | High throughput | no | yes |
| FGD5_HUMAN | [view interactions] | High throughput | no | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSK22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RTN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PKHA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLK4_HUMAN | [view interactions] | High throughput | no | yes |
| RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ACTC_HUMAN | [view interactions] | High throughput | no | no |
| RN183_HUMAN | [view interactions] | High throughput | no | no |
| ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| ANXA7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| CDN1A_HUMAN | [view interactions] | High throughput | no | no |
| GRB7_HUMAN | [view interactions] | High throughput | no | no |
| PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
| RPP14_HUMAN | [view interactions] | High throughput | no | no |
| SMN_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KITH_HUMAN | [view interactions] | High throughput | no | yes |
| NSD3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARK4_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP19_HUMAN | [view interactions] | High throughput | no | no |
| UBP7_HUMAN | [view interactions] | High throughput | no | yes |
| MLP3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASFA_HUMAN | [view interactions] | High throughput | no | no |
| CRLF3_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH3_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH2_HUMAN | [view interactions] | High throughput | no | no |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| MOB1A_HUMAN | [view interactions] | High throughput | no | yes |
| MOB1B_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH1_HUMAN | [view interactions] | High throughput | no | yes |
| DOCK6_HUMAN | [view interactions] | High throughput | no | yes |
| LRCH4_HUMAN | [view interactions] | High throughput | no | no |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| HTRA2_HUMAN | [view interactions] | High throughput | no | yes |
| IMP1L_HUMAN | [view interactions] | High throughput | no | yes |
| IMP2L_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| HMGA2_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MED23_HUMAN | [view interactions] | High throughput | no | no |
| AKT3_HUMAN | [view interactions] | High throughput | no | yes |
| B2L14_HUMAN | [view interactions] | High throughput | no | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HERC2_HUMAN | [view interactions] | High throughput | no | yes |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC16A_HUMAN | [view interactions] | High throughput | no | yes |
| VAC14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BMI1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
| CSAG1_HUMAN | [view interactions] | High throughput | no | no |
| CSAG2_HUMAN | [view interactions] | High throughput | no | no |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF2AA_HUMAN | [view interactions] | High throughput | no | yes |
| MLH1_HUMAN | [view interactions] | High throughput | no | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AURKB_HUMAN | [view interactions] | High throughput | no | yes |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| GCP3_HUMAN | [view interactions] | High throughput | no | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NRG1_HUMAN | [view entry] [view interactions] | Computational | yes | no |