FKB15_HUMAN
Evidence for PS localization
Functions
May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase . Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FKB15_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 29.1667 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 25.0000 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 25.0000 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 25.0000 | 4 | no |
| GO:0003779 | actin binding | 20.8333 | 4 | yes |
| GO:0003723 | RNA binding | 20.8333 | 4 | no |
| GO:0005524 | ATP binding | 20.8333 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 20.8333 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FKB15_HUMAN |
|---|---|---|---|---|
| GO:0016192 | vesicle-mediated transport | 58.3333 | 4 | yes |
| GO:0008104 | protein localization | 58.3333 | 4 | no |
| GO:0015031 | protein transport | 54.1667 | 4 | no |
| GO:0071702 | organic substance transport | 54.1667 | 4 | no |
| GO:0071705 | nitrogen compound transport | 54.1667 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 50.0000 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 50.0000 | 4 | no |
| GO:0006996 | organelle organization | 45.8333 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 45.8333 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 45.8333 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 45.8333 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 45.8333 | 4 | no |
| GO:0006886 | intracellular protein transport | 41.6667 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.6667 | 4 | no |
| GO:0022607 | cellular component assembly | 41.6667 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 37.5000 | 5 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 37.5000 | 5 | no |
| GO:0009894 | regulation of catabolic process | 37.5000 | 4 | no |
| GO:0051049 | regulation of transport | 33.3333 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 33.3333 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 33.3333 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 33.3333 | 5 | no |
| GO:0060341 | regulation of cellular localization | 29.1667 | 4 | no |
| GO:0031329 | regulation of cellular catabolic process | 29.1667 | 5 | no |
| GO:0006897 | endocytosis | 25.0000 | 5 | yes |
| GO:0036211 | protein modification process | 25.0000 | 4 | no |
| GO:0043412 | macromolecule modification | 25.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 25.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 25.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 25.0000 | 5 | no |
| GO:0032880 | regulation of protein localization | 25.0000 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 25.0000 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 25.0000 | 6 | no |
| GO:0007034 | vacuolar transport | 20.8333 | 4 | no |
| GO:0007041 | lysosomal transport | 20.8333 | 5 | no |
| GO:0033365 | protein localization to organelle | 20.8333 | 5 | no |
| GO:0043254 | regulation of protein-containing complex assembly | 20.8333 | 5 | no |
| GO:0051050 | positive regulation of transport | 20.8333 | 4 | no |
| GO:0042176 | regulation of protein catabolic process | 20.8333 | 5 | no |
| GO:0016197 | endosomal transport | 20.8333 | 4 | no |
| GO:0098876 | vesicle-mediated transport to the plasma membrane | 20.8333 | 4 | no |
| GO:0009966 | regulation of signal transduction | 20.8333 | 4 | no |
| GO:0010646 | regulation of cell communication | 20.8333 | 4 | no |
| GO:0009896 | positive regulation of catabolic process | 20.8333 | 5 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FKB15_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WAC2C_HUMAN | [view interactions] | Low throughput | no | yes |
| VPS35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPS29_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASH1_HUMAN | [view interactions] | Low throughput | no | yes |
| WASC5_HUMAN | [view interactions] | Low throughput | no | yes |
| WASC4_HUMAN | [view interactions] | Low throughput | no | yes |
| TTBK2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| CYTD_HUMAN | [view interactions] | High throughput | no | no |
| CCBE1_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| POC1A_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| CDK19_HUMAN | [view interactions] | High throughput | no | yes |
| AP3B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F193A_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN326_HUMAN | [view interactions] | High throughput | no | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOT_HUMAN | [view interactions] | High throughput | no | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TF2L1_HUMAN | [view interactions] | High throughput | no | yes |
| CTR9_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VP26B_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GAB1_HUMAN | [view interactions] | High throughput | no | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| INSR_HUMAN | [view interactions] | High throughput | no | yes |
| AIPL1_HUMAN | [view interactions] | High throughput | no | no |
| STRN3_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| PDE5A_HUMAN | [view interactions] | High throughput | no | yes |
| MIO_HUMAN | [view interactions] | High throughput | no | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
| NUD12_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COMDA_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| VA0D2_HUMAN | [view interactions] | High throughput | no | no |
| PAI2_HUMAN | [view interactions] | High throughput | no | no |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| CA087_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGDP1_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| N62CL_HUMAN | [view interactions] | High throughput | no | no |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP4_HUMAN | [view interactions] | High throughput | no | no |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| BOP1_HUMAN | [view interactions] | Computational | no | yes |
| GNL3_HUMAN | [view interactions] | Computational | no | yes |
| GNL3L_HUMAN | [view interactions] | Computational | no | yes |
| WDR3_HUMAN | [view interactions] | Computational | no | no |
| RPA2_HUMAN | [view interactions] | Computational | no | no |
| NOC2L_HUMAN | [view interactions] | Computational | no | yes |
| NOP56_HUMAN | [view interactions] | Computational | no | yes |
| MK67I_HUMAN | [view interactions] | Computational | no | yes |
| RLP24_HUMAN | [view interactions] | Computational | no | yes |
| GTPB4_HUMAN | [view interactions] | Computational | no | yes |
| RRP15_HUMAN | [view interactions] | Computational | no | yes |
| NLE1_HUMAN | [view interactions] | Computational | no | yes |
| DDX55_HUMAN | [view interactions] | Computational | no | yes |
| MAK16_HUMAN | [view interactions] | Computational | no | yes |
| MRT4_HUMAN | [view interactions] | Computational | no | yes |
| KRR1_HUMAN | [view interactions] | Computational | no | yes |
| RPF2_HUMAN | [view interactions] | Computational | no | yes |
| NOP9_HUMAN | [view interactions] | Computational | no | no |
| RRP1B_HUMAN | [view interactions] | Computational | no | yes |
| BRX1_HUMAN | [view interactions] | Computational | no | no |
| BMS1_HUMAN | [view interactions] | Computational | no | yes |
| NOLC1_HUMAN | [view interactions] | Computational | no | yes |
| PESC_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| WDR43_HUMAN | [view interactions] | Computational | no | yes |
| TSR1_HUMAN | [view interactions] | Computational | no | no |
| LYAR_HUMAN | [view interactions] | Computational | no | no |
| NMD3_HUMAN | [view interactions] | Computational | no | no |
| NOP14_HUMAN | [view interactions] | Computational | no | yes |
| KRI1_HUMAN | [view interactions] | Computational | no | yes |
| SAS10_HUMAN | [view interactions] | Computational | no | yes |
| PUM3_HUMAN | [view interactions] | Computational | no | yes |
| IMP4_HUMAN | [view interactions] | Computational | no | no |
| RPA43_HUMAN | [view interactions] | Computational | no | yes |
| NPM3_HUMAN | [view interactions] | Computational | no | yes |
| RL1D1_HUMAN | [view interactions] | Computational | no | yes |
| RBM28_HUMAN | [view interactions] | Computational | no | yes |
| NOL10_HUMAN | [view interactions] | Computational | no | yes |
| RRS1_HUMAN | [view interactions] | Computational | no | yes |
| BYST_HUMAN | [view interactions] | Computational | no | yes |
| SDA1_HUMAN | [view interactions] | Computational | no | yes |
| DDX10_HUMAN | [view interactions] | Computational | no | yes |
| NOP58_HUMAN | [view interactions] | Computational | no | yes |
| RRP5_HUMAN | [view interactions] | Computational | no | yes |
| RPA1_HUMAN | [view interactions] | Computational | no | yes |
| ESF1_HUMAN | [view interactions] | Computational | no | yes |
| NIP7_HUMAN | [view interactions] | Computational | no | yes |
| NHP2_HUMAN | [view interactions] | Computational | no | yes |
| RPF1_HUMAN | [view interactions] | Computational | no | yes |
| SPB1_HUMAN | [view interactions] | Computational | no | yes |
| GRWD1_HUMAN | [view interactions] | Computational | no | no |
| RRP1_HUMAN | [view interactions] | Computational | no | yes |