FKB15_HUMAN
Evidence for PS localization
Functions
May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase . Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in FKB15_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 25.0000 | 4 | no |
| GO:0000166 | nucleotide binding | 22.2222 | 4 | no |
| GO:0017076 | purine nucleotide binding | 22.2222 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 22.2222 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.2222 | 4 | no |
| GO:0003723 | RNA binding | 22.2222 | 4 | no |
| GO:0003779 | actin binding | 19.4444 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in FKB15_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 58.3333 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 58.3333 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 55.5556 | 4 | no |
| GO:0071702 | organic substance transport | 52.7778 | 4 | no |
| GO:0071705 | nitrogen compound transport | 52.7778 | 4 | no |
| GO:0015031 | protein transport | 50.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 50.0000 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 47.2222 | 4 | no |
| GO:0006996 | organelle organization | 41.6667 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 41.6667 | 4 | no |
| GO:0022607 | cellular component assembly | 41.6667 | 4 | no |
| GO:0006886 | intracellular protein transport | 38.8889 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.8889 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 38.8889 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 36.1111 | 5 | no |
| GO:0009894 | regulation of catabolic process | 36.1111 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 36.1111 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 33.3333 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 33.3333 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 33.3333 | 5 | no |
| GO:0098657 | import into cell | 30.5556 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 30.5556 | 4 | no |
| GO:0010646 | regulation of cell communication | 30.5556 | 4 | no |
| GO:0010468 | regulation of gene expression | 30.5556 | 6 | no |
| GO:0044087 | regulation of cellular component biogenesis | 30.5556 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 27.7778 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 27.7778 | 5 | no |
| GO:0043933 | protein-containing complex organization | 25.0000 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 25.0000 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 25.0000 | 5 | no |
| GO:0033043 | regulation of organelle organization | 25.0000 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 25.0000 | 4 | no |
| GO:0036211 | protein modification process | 22.2222 | 4 | no |
| GO:0043412 | macromolecule modification | 22.2222 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 22.2222 | 4 | no |
| GO:0010506 | regulation of autophagy | 22.2222 | 6 | no |
| GO:0031329 | regulation of cellular catabolic process | 22.2222 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.2222 | 7 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 22.2222 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 22.2222 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 22.2222 | 5 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.2222 | 6 | no |
| GO:0051049 | regulation of transport | 22.2222 | 4 | no |
| GO:0060341 | regulation of cellular localization | 22.2222 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| FKB15_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| VPS35_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WAC2C_HUMAN | [view interactions] | Low throughput | no | yes |
| VPS29_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| WASH1_HUMAN | [view interactions] | Low throughput | no | yes |
| WASC5_HUMAN | [view interactions] | Low throughput | no | yes |
| WASC4_HUMAN | [view interactions] | Low throughput | no | yes |
| TTBK2_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ERR2_HUMAN | [view interactions] | High throughput | no | no |
| CTR9_HUMAN | [view interactions] | High throughput | no | yes |
| PRP4_HUMAN | [view interactions] | High throughput | no | yes |
| VP26A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VP26B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIPL1_HUMAN | [view interactions] | High throughput | no | no |
| STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PDE5A_HUMAN | [view interactions] | High throughput | no | yes |
| MIOS_HUMAN | [view interactions] | High throughput | no | yes |
| CEP43_HUMAN | [view interactions] | High throughput | no | no |
| SP1_HUMAN | [view interactions] | High throughput | no | yes |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| LGR4_HUMAN | [view interactions] | High throughput | no | yes |
| SNP29_HUMAN | [view interactions] | High throughput | no | yes |
| ITPI2_HUMAN | [view interactions] | High throughput | no | yes |
| NUD12_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COMDA_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| VA0D2_HUMAN | [view interactions] | High throughput | no | no |
| PAI2_HUMAN | [view interactions] | High throughput | no | no |
| STX11_HUMAN | [view interactions] | High throughput | no | yes |
| CA087_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| ZUP1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MGDP1_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| BRD4_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| N62CL_HUMAN | [view interactions] | High throughput | no | no |
| HSP72_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| MFAP4_HUMAN | [view interactions] | High throughput | no | no |
| LURA1_HUMAN | [view interactions] | High throughput | no | yes |
| BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NUP62_HUMAN | [view interactions] | High throughput | no | yes |
| CYTD_HUMAN | [view interactions] | High throughput | no | no |
| CCBE1_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WASC3_HUMAN | [view interactions] | High throughput | no | yes |
| POC1A_HUMAN | [view interactions] | High throughput | no | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DJC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FOXC1_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MK14_HUMAN | [view interactions] | High throughput | no | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| CDK19_HUMAN | [view interactions] | High throughput | no | yes |
| AP3B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F193A_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN326_HUMAN | [view interactions] | High throughput | no | yes |
| NEDD4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NP1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SART3_HUMAN | [view interactions] | High throughput | no | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| CHERP_HUMAN | [view interactions] | High throughput | no | no |
| MIER1_HUMAN | [view interactions] | High throughput | no | no |
| ARHG1_HUMAN | [view interactions] | High throughput | no | no |
| ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NP1L4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB9A_HUMAN | [view interactions] | High throughput | no | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZFY16_HUMAN | [view interactions] | High throughput | no | yes |
| COR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |