RHEB_HUMAN
Evidence for PS localization
Functions
Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in RHEB_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 31.5789 | 4 | yes |
| GO:0000166 | nucleotide binding | 28.9474 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 28.9474 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 26.3158 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 26.3158 | 4 | yes |
| GO:0043169 | cation binding | 25.0000 | 4 | yes |
| GO:0046872 | metal ion binding | 23.6842 | 5 | yes |
| GO:0019900 | kinase binding | 17.1053 | 4 | yes |
| GO:0016462 | pyrophosphatase activity | 14.4737 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 14.4737 | 4 | yes |
| GO:0019901 | protein kinase binding | 14.4737 | 5 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 13.1579 | 6 | yes |
| GO:0005525 | GTP binding | 11.8421 | 5 | yes |
| GO:0019001 | guanyl nucleotide binding | 11.8421 | 6 | yes |
| GO:0032561 | guanyl ribonucleotide binding | 11.8421 | 5 | yes |
| GO:0003924 | GTPase activity | 10.5263 | 7 | yes |
| GO:0019003 | GDP binding | 9.2105 | 5 | yes |
| GO:0000287 | magnesium ion binding | 5.2632 | 6 | yes |
| GO:0019887 | protein kinase regulator activity | 3.9474 | 4 | yes |
| GO:0019209 | kinase activator activity | 2.6316 | 4 | yes |
| GO:0030295 | protein kinase activator activity | 2.6316 | 5 | yes |
| GO:0043539 | protein serine/threonine kinase activator activity | 2.6316 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in RHEB_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.5263 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 55.2632 | 4 | no |
| GO:0010646 | regulation of cell communication | 53.9474 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 51.3158 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 48.6842 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 48.6842 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 46.0526 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 44.7368 | 4 | no |
| GO:0006996 | organelle organization | 40.7895 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 38.1579 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 36.8421 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 36.8421 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 35.5263 | 5 | no |
| GO:0023056 | positive regulation of signaling | 35.5263 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 35.5263 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 35.5263 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 35.5263 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 34.2105 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 34.2105 | 5 | yes |
| GO:0042981 | regulation of apoptotic process | 32.8947 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 32.8947 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.5789 | 5 | no |
| GO:0051049 | regulation of transport | 31.5789 | 4 | no |
| GO:0009967 | positive regulation of signal transduction | 31.5789 | 5 | yes |
| GO:0033043 | regulation of organelle organization | 31.5789 | 5 | no |
| GO:0010468 | regulation of gene expression | 31.5789 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 30.2632 | 5 | no |
| GO:0008104 | protein localization | 30.2632 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.2632 | 5 | no |
| GO:0022607 | cellular component assembly | 27.6316 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 27.6316 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.6316 | 5 | no |
| GO:0031399 | regulation of protein modification process | 26.3158 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 25.0000 | 5 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 25.0000 | 5 | no |
| GO:0009894 | regulation of catabolic process | 25.0000 | 4 | yes |
| GO:1902533 | positive regulation of intracellular signal transduction | 25.0000 | 6 | yes |
| GO:0071702 | organic substance transport | 25.0000 | 4 | no |
| GO:0006915 | apoptotic process | 25.0000 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 25.0000 | 6 | no |
| GO:0023057 | negative regulation of signaling | 23.6842 | 4 | no |
| GO:0048585 | negative regulation of response to stimulus | 23.6842 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 23.6842 | 6 | no |
| GO:0060341 | regulation of cellular localization | 23.6842 | 4 | no |
| GO:0009968 | negative regulation of signal transduction | 23.6842 | 5 | no |
| GO:0010648 | negative regulation of cell communication | 23.6842 | 5 | no |
| GO:0042325 | regulation of phosphorylation | 22.3684 | 7 | no |
| GO:0043066 | negative regulation of apoptotic process | 22.3684 | 6 | no |
| GO:0043069 | negative regulation of programmed cell death | 22.3684 | 5 | no |
| GO:0032880 | regulation of protein localization | 22.3684 | 5 | no |
| GO:0080134 | regulation of response to stress | 22.3684 | 4 | no |
| GO:0043933 | protein-containing complex organization | 22.3684 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 22.3684 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 22.3684 | 7 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 22.3684 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.0526 | 6 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.0526 | 5 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 21.0526 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 21.0526 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 21.0526 | 4 | yes |
| GO:0030030 | cell projection organization | 21.0526 | 4 | no |
| GO:0044089 | positive regulation of cellular component biogenesis | 21.0526 | 5 | no |
| GO:0071705 | nitrogen compound transport | 21.0526 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 21.0526 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 19.7368 | 4 | yes |
| GO:0031329 | regulation of cellular catabolic process | 18.4211 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 18.4211 | 4 | yes |
| GO:0141124 | intracellular signaling cassette | 18.4211 | 4 | yes |
| GO:0010506 | regulation of autophagy | 15.7895 | 6 | yes |
| GO:0051241 | negative regulation of multicellular organismal process | 15.7895 | 4 | yes |
| GO:0051726 | regulation of cell cycle | 14.4737 | 4 | yes |
| GO:0060284 | regulation of cell development | 14.4737 | 5 | yes |
| GO:2000026 | regulation of multicellular organismal development | 14.4737 | 4 | yes |
| GO:0016241 | regulation of macroautophagy | 13.1579 | 7 | yes |
| GO:0050767 | regulation of neurogenesis | 13.1579 | 6 | yes |
| GO:0051960 | regulation of nervous system development | 13.1579 | 5 | yes |
| GO:0045597 | positive regulation of cell differentiation | 11.8421 | 5 | yes |
| GO:0007264 | small GTPase-mediated signal transduction | 10.5263 | 5 | yes |
| GO:0010720 | positive regulation of cell development | 9.2105 | 6 | yes |
| GO:0050769 | positive regulation of neurogenesis | 9.2105 | 6 | yes |
| GO:0051962 | positive regulation of nervous system development | 9.2105 | 5 | yes |
| GO:0010001 | glial cell differentiation | 7.8947 | 4 | yes |
| GO:0032006 | regulation of TOR signaling | 7.8947 | 6 | yes |
| GO:1903432 | regulation of TORC1 signaling | 7.8947 | 7 | yes |
| GO:0014013 | regulation of gliogenesis | 6.5789 | 7 | yes |
| GO:0014015 | positive regulation of gliogenesis | 6.5789 | 7 | yes |
| GO:0045685 | regulation of glial cell differentiation | 5.2632 | 5 | yes |
| GO:0045687 | positive regulation of glial cell differentiation | 5.2632 | 6 | yes |
| GO:0048709 | oligodendrocyte differentiation | 5.2632 | 5 | yes |
| GO:0032008 | positive regulation of TOR signaling | 3.9474 | 7 | yes |
| GO:0048713 | regulation of oligodendrocyte differentiation | 3.9474 | 6 | yes |
| GO:0048714 | positive regulation of oligodendrocyte differentiation | 3.9474 | 7 | yes |
| GO:1904263 | positive regulation of TORC1 signaling | 3.9474 | 8 | yes |
| GO:0120161 | regulation of cold-induced thermogenesis | 2.6316 | 4 | yes |
| GO:0120163 | negative regulation of cold-induced thermogenesis | 2.6316 | 5 | yes |
| GO:2000074 | regulation of type B pancreatic cell development | 2.6316 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| MTOR_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PDE6D_HUMAN | [view interactions] | Low throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TCTP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| PLD1_HUMAN | [view interactions] | Low throughput | no | no |
| TSC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TSC2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RPTOR_HUMAN | [view interactions] | Low throughput | no | yes |
| BNIP3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BNI3L_HUMAN | [view interactions] | Low throughput | no | yes |
| PRAF1_HUMAN | [view interactions] | Low throughput | no | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ATM_HUMAN | [view interactions] | Low throughput | no | yes |
| ATR_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RASH_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| RAP1A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RN152_HUMAN | [view interactions] | Low throughput | no | no |
| UBP4_HUMAN | [view interactions] | Low throughput | no | no |
| ATX3_HUMAN | [view interactions] | Low throughput | no | yes |
| KS6B1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB7A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| RAB9A_HUMAN | [view interactions] | Low throughput | no | yes |
| CREB1_HUMAN | [view interactions] | Low throughput | no | yes |
| DP13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GO45_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| CREB3_HUMAN | [view interactions] | High throughput | no | no |
| S15A1_HUMAN | [view interactions] | High throughput | no | no |
| I20RA_HUMAN | [view interactions] | High throughput | no | no |
| NF2IP_HUMAN | [view interactions] | High throughput | no | no |
| LEG7_HUMAN | [view interactions] | High throughput | no | no |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| CASL_HUMAN | [view interactions] | High throughput | no | yes |
| RELL2_HUMAN | [view interactions] | High throughput | no | no |
| UBB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRPRB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPT19_HUMAN | [view interactions] | High throughput | no | no |
| ENPP7_HUMAN | [view interactions] | High throughput | no | no |
| KI67_HUMAN | [view interactions] | High throughput | no | no |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| PKHM1_HUMAN | [view interactions] | High throughput | no | yes |
| EIF1B_HUMAN | [view interactions] | High throughput | no | no |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ANS1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A2MG_HUMAN | [view interactions] | High throughput | no | yes |
| ECSIT_HUMAN | [view interactions] | High throughput | no | yes |
| PSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NCAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARI2_HUMAN | [view interactions] | High throughput | no | no |
| APBP2_HUMAN | [view interactions] | High throughput | no | yes |
| CASP6_HUMAN | [view interactions] | High throughput | no | no |
| CCKN_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| NMDE3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| JMY_HUMAN | [view interactions] | High throughput | no | yes |
| PCNA_HUMAN | [view interactions] | High throughput | no | no |
| TRI63_HUMAN | [view interactions] | High throughput | no | no |
| TRI55_HUMAN | [view interactions] | High throughput | no | no |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| APOE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| VPS4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB8_HUMAN | [view interactions] | High throughput | no | no |
| 5HT6R_HUMAN | [view interactions] | High throughput | no | yes |
| DUS19_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LAMP2_HUMAN | [view interactions] | High throughput | no | yes |
| TM52B_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| SC5A5_HUMAN | [view interactions] | High throughput | no | no |
| MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
| VASH2_HUMAN | [view interactions] | High throughput | no | no |
| LMNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQM_HUMAN | [view interactions] | High throughput | no | no |
| GBG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GP182_HUMAN | [view interactions] | High throughput | no | no |
| PGFRA_HUMAN | [view interactions] | High throughput | no | no |
| ENTP2_HUMAN | [view interactions] | High throughput | no | yes |
| PPBI_HUMAN | [view interactions] | High throughput | no | no |
| STMN3_HUMAN | [view interactions] | High throughput | no | yes |
| TGM3_HUMAN | [view interactions] | High throughput | no | no |
| FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| CAVN3_HUMAN | [view interactions] | High throughput | no | no |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| PJA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| SPPL3_HUMAN | [view interactions] | High throughput | no | no |
| LDHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| API5_HUMAN | [view interactions] | High throughput | no | no |
| AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUDT9_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACYP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARFG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG35_HUMAN | [view interactions] | High throughput | no | yes |
| ATP5H_HUMAN | [view interactions] | High throughput | no | yes |
| BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BSDC1_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT2_HUMAN | [view interactions] | High throughput | no | yes |
| CYTB_HUMAN | [view interactions] | High throughput | no | no |
| EHBP1_HUMAN | [view interactions] | High throughput | no | yes |
| FABP7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F169A_HUMAN | [view interactions] | High throughput | no | yes |
| FKB15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HMGA1_HUMAN | [view interactions] | High throughput | no | yes |
| KCNA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LZTL1_HUMAN | [view interactions] | High throughput | no | no |
| MAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAP4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NSF1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCCB_HUMAN | [view interactions] | High throughput | no | yes |
| PCNP_HUMAN | [view interactions] | High throughput | no | yes |
| HAP28_HUMAN | [view interactions] | High throughput | no | yes |
| PROF2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRDX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBGPR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RABE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUFY3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPB6_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYUB_HUMAN | [view interactions] | High throughput | no | yes |
| STMN1_HUMAN | [view interactions] | High throughput | no | yes |
| STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZO2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TPD54_HUMAN | [view interactions] | High throughput | no | yes |
| TPIS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| THIO_HUMAN | [view interactions] | High throughput | no | yes |
| TXD12_HUMAN | [view interactions] | High throughput | no | no |
| UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFC1_HUMAN | [view interactions] | High throughput | no | yes |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |