SI1L2_HUMAN
Evidence for PS localization
Functions
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in SI1L2_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 26.0870 | 4 | no |
| GO:0045296 | cadherin binding | 23.9130 | 4 | no |
| GO:0019901 | protein kinase binding | 23.9130 | 5 | no |
| GO:0043168 | anion binding | 21.7391 | 4 | no |
| GO:0005096 | GTPase activator activity | 10.8696 | 4 | yes |
| GO:0030695 | GTPase regulator activity | 10.8696 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in SI1L2_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 60.8696 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 58.6957 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 58.6957 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 56.5217 | 4 | no |
| GO:0010646 | regulation of cell communication | 54.3478 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 54.3478 | 4 | no |
| GO:0006996 | organelle organization | 52.1739 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 50.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 43.4783 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 41.3043 | 4 | no |
| GO:0010468 | regulation of gene expression | 41.3043 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 41.3043 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 41.3043 | 5 | no |
| GO:0008104 | protein localization | 41.3043 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 36.9565 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 36.9565 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.9565 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 36.9565 | 5 | no |
| GO:0022607 | cellular component assembly | 34.7826 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 34.7826 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 32.6087 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 32.6087 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 30.4348 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 30.4348 | 4 | no |
| GO:0007010 | cytoskeleton organization | 28.2609 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 28.2609 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 28.2609 | 6 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 28.2609 | 6 | no |
| GO:0031399 | regulation of protein modification process | 28.2609 | 6 | no |
| GO:0051049 | regulation of transport | 28.2609 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 26.0870 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 26.0870 | 4 | no |
| GO:2000026 | regulation of multicellular organismal development | 26.0870 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 23.9130 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 23.9130 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.9130 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 23.9130 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 23.9130 | 6 | no |
| GO:0023057 | negative regulation of signaling | 23.9130 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 23.9130 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 23.9130 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 23.9130 | 5 | no |
| GO:0051240 | positive regulation of multicellular organismal process | 23.9130 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 23.9130 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 23.9130 | 4 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 23.9130 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 23.9130 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 23.9130 | 5 | no |
| GO:0030030 | cell projection organization | 21.7391 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 21.7391 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 21.7391 | 5 | no |
| GO:0023056 | positive regulation of signaling | 21.7391 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 21.7391 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 21.7391 | 6 | no |
| GO:0032880 | regulation of protein localization | 21.7391 | 5 | no |
| GO:0060341 | regulation of cellular localization | 21.7391 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 21.7391 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 21.7391 | 6 | no |
| GO:0071702 | organic substance transport | 21.7391 | 4 | no |
| GO:0071705 | nitrogen compound transport | 21.7391 | 4 | no |
| GO:0051056 | regulation of small GTPase mediated signal transduction | 19.5652 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ORC5_HUMAN | [view interactions] | High throughput | no | yes |
| TGM2_HUMAN | [view interactions] | High throughput | no | no |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGLN3_HUMAN | [view interactions] | High throughput | no | no |
| NXF2_HUMAN | [view interactions] | High throughput | no | no |
| CF141_HUMAN | [view interactions] | High throughput | no | no |
| CELA1_HUMAN | [view interactions] | High throughput | no | no |
| PRG2_HUMAN | [view interactions] | High throughput | no | no |
| LZTS2_HUMAN | [view interactions] | High throughput | no | no |
| ABC3D_HUMAN | [view interactions] | High throughput | no | yes |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSYL1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SF3B2_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYR1B_HUMAN | [view interactions] | High throughput | no | no |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| CK5P2_HUMAN | [view interactions] | High throughput | no | yes |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| FERM2_HUMAN | [view interactions] | High throughput | no | yes |
| LATS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LATS2_HUMAN | [view interactions] | High throughput | no | yes |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| FTM_HUMAN | [view interactions] | High throughput | no | yes |
| ADIP_HUMAN | [view interactions] | High throughput | no | yes |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TEANC_HUMAN | [view interactions] | High throughput | no | no |
| CP250_HUMAN | [view interactions] | High throughput | no | no |
| FBW1B_HUMAN | [view interactions] | High throughput | no | yes |
| PCGF1_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA4_HUMAN | [view interactions] | High throughput | no | no |
| NANOG_HUMAN | [view interactions] | High throughput | no | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| PROZ_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| PTN18_HUMAN | [view interactions] | High throughput | no | yes |
| FBXW8_HUMAN | [view interactions] | High throughput | no | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI66_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| SYMM_HUMAN | [view interactions] | High throughput | no | yes |
| TRI52_HUMAN | [view interactions] | High throughput | no | yes |
| KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
| DUS16_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| N4BP3_HUMAN | [view interactions] | High throughput | no | yes |
| UBR1_HUMAN | [view interactions] | High throughput | no | yes |
| RGAP1_HUMAN | [view interactions] | High throughput | no | no |
| NRSN1_HUMAN | [view interactions] | High throughput | no | yes |
| LZTS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCD96_HUMAN | [view interactions] | High throughput | no | no |
| K22E_HUMAN | [view interactions] | High throughput | no | no |
| SI1L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIPA1_HUMAN | [view interactions] | High throughput | no | yes |
| PMGT2_HUMAN | [view interactions] | High throughput | no | yes |
| CCZ1_HUMAN | [view interactions] | High throughput | no | yes |
| U119B_HUMAN | [view interactions] | High throughput | no | yes |
| SNX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BRE1A_HUMAN | [view interactions] | High throughput | no | yes |
| U119A_HUMAN | [view interactions] | High throughput | no | no |
| TOM22_HUMAN | [view interactions] | High throughput | no | yes |
| LZTS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SOX2_HUMAN | [view interactions] | High throughput | no | yes |
| MIF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| CL16A_HUMAN | [view interactions] | High throughput | no | yes |
| CE152_HUMAN | [view interactions] | High throughput | no | yes |
| GARL3_HUMAN | [view interactions] | High throughput | no | yes |
| ICE1_HUMAN | [view interactions] | High throughput | no | yes |
| ICE2_HUMAN | [view interactions] | High throughput | no | no |
| K1549_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGPA2_HUMAN | [view interactions] | High throughput | no | yes |
| TROAP_HUMAN | [view interactions] | High throughput | no | yes |
| BICD1_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK1_HUMAN | [view interactions] | High throughput | no | no |
| NIN_HUMAN | [view interactions] | High throughput | no | no |
| GRRE1_HUMAN | [view interactions] | High throughput | no | no |
| PATL1_HUMAN | [view interactions] | High throughput | no | yes |
| SMAG2_HUMAN | [view interactions] | High throughput | no | yes |
| DJB13_HUMAN | [view interactions] | High throughput | no | no |
| F184A_HUMAN | [view interactions] | High throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOT_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANC2_HUMAN | [view interactions] | High throughput | no | no |
| ANFY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BORC6_HUMAN | [view interactions] | High throughput | no | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEN6A_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| K1C18_HUMAN | [view interactions] | High throughput | no | no |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AFAD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PARD3_HUMAN | [view interactions] | High throughput | no | yes |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SAS6_HUMAN | [view interactions] | High throughput | no | no |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| VASP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| RHEB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |