DDX6_HUMAN
Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions (PubMed, PubMed, PubMed). Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation (PubMed). In the process of mRNA degradation, plays a role in mRNA decapping (PubMed). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
No data found.
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 372 | His | Arg | Intellectualdevelopmentaldisorderwithimpairedlanguageanddysmorphicfacies(IDDILF) | - |
| 373 | Arg | Gln | Intellectualdevelopmentaldisorderwithimpairedlanguageanddysmorphicfacies(IDDILF) | - |
| 390 | Cys | Arg | Intellectualdevelopmentaldisorderwithimpairedlanguageanddysmorphicfacies(IDDILF) | - |
| 391 | Thr | Ile | Intellectualdevelopmentaldisorderwithimpairedlanguageanddysmorphicfacies(IDDILF) | - |
| 391 | Thr | Pro | Intellectualdevelopmentaldisorderwithimpairedlanguageanddysmorphicfacies(IDDILF) | - |
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DDX6_HUMAN |
|---|---|---|---|---|
| GO:0003723 | RNA binding | 65.6977 | 4 | yes |
| GO:0003729 | mRNA binding | 22.6744 | 5 | yes |
| GO:0043168 | anion binding | 16.8605 | 4 | yes |
| GO:0045296 | cadherin binding | 16.8605 | 4 | yes |
| GO:0000166 | nucleotide binding | 15.6977 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 15.6977 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 15.1163 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 15.1163 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 13.3721 | 6 | yes |
| GO:0005524 | ATP binding | 12.7907 | 5 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 12.7907 | 5 | yes |
| GO:0016462 | pyrophosphatase activity | 7.5581 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 7.5581 | 4 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 7.5581 | 6 | yes |
| GO:0016887 | ATP hydrolysis activity | 5.8140 | 7 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DDX6_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 49.4186 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 48.2558 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 47.6744 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 43.6047 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 43.6047 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 43.6047 | 5 | yes |
| GO:0010468 | regulation of gene expression | 43.0233 | 6 | yes |
| GO:0048522 | positive regulation of cellular process | 43.0233 | 4 | no |
| GO:0009059 | macromolecule biosynthetic process | 42.4419 | 4 | no |
| GO:1901566 | organonitrogen compound biosynthetic process | 39.5349 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 38.9535 | 4 | yes |
| GO:0006412 | translation | 37.7907 | 4 | no |
| GO:0022607 | cellular component assembly | 36.0465 | 4 | yes |
| GO:0002181 | cytoplasmic translation | 34.8837 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 34.3023 | 4 | yes |
| GO:0051246 | regulation of protein metabolic process | 33.7209 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.5581 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 32.5581 | 4 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.9767 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 30.8140 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 30.8140 | 5 | no |
| GO:0006996 | organelle organization | 29.6512 | 4 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 29.6512 | 5 | yes |
| GO:0010646 | regulation of cell communication | 28.4884 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.4884 | 5 | no |
| GO:0043933 | protein-containing complex organization | 27.3256 | 4 | no |
| GO:0008104 | protein localization | 26.7442 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 26.1628 | 5 | no |
| GO:0009890 | negative regulation of biosynthetic process | 25.5814 | 5 | yes |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 25.5814 | 6 | yes |
| GO:0031327 | negative regulation of cellular biosynthetic process | 25.5814 | 6 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 25.5814 | 6 | no |
| GO:0090304 | nucleic acid metabolic process | 25.5814 | 4 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 25.0000 | 6 | no |
| GO:0051128 | regulation of cellular component organization | 25.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 23.8372 | 4 | no |
| GO:0016070 | RNA metabolic process | 23.8372 | 5 | no |
| GO:0065003 | protein-containing complex assembly | 23.2558 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 22.0930 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 22.0930 | 6 | no |
| GO:0009894 | regulation of catabolic process | 20.3488 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 20.3488 | 6 | no |
| GO:0051248 | negative regulation of protein metabolic process | 19.1860 | 6 | yes |
| GO:0010608 | post-transcriptional regulation of gene expression | 18.6047 | 7 | yes |
| GO:0010629 | negative regulation of gene expression | 18.0233 | 7 | yes |
| GO:0006417 | regulation of translation | 15.6977 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 12.2093 | 4 | yes |
| GO:0070925 | organelle assembly | 10.4651 | 5 | yes |
| GO:0051093 | negative regulation of developmental process | 8.7209 | 4 | yes |
| GO:0017148 | negative regulation of translation | 7.5581 | 7 | yes |
| GO:0140694 | non-membrane-bounded organelle assembly | 7.5581 | 6 | yes |
| GO:0045596 | negative regulation of cell differentiation | 5.8140 | 5 | yes |
| GO:0030182 | neuron differentiation | 4.0698 | 4 | yes |
| GO:0031047 | regulatory ncRNA-mediated gene silencing | 4.0698 | 8 | yes |
| GO:0016441 | post-transcriptional gene silencing | 3.4884 | 8 | yes |
| GO:0034063 | stress granule assembly | 3.4884 | 7 | yes |
| GO:0045664 | regulation of neuron differentiation | 2.9070 | 5 | yes |
| GO:0035194 | regulatory ncRNA-mediated post-transcriptional gene silencing | 2.3256 | 9 | yes |
| GO:0035195 | miRNA-mediated post-transcriptional gene silencing | 1.7442 | 10 | yes |
| GO:0035278 | miRNA-mediated gene silencing by inhibition of translation | 1.7442 | 8 | yes |
| GO:0045665 | negative regulation of neuron differentiation | 1.1628 | 6 | yes |
Disease
No data found.
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| PATL1_HUMAN | [view interactions] | Low throughput | no | yes |
| LS14A_HUMAN | [view interactions] | Low throughput | no | yes |
| 4ET_HUMAN | [view interactions] | Low throughput | no | yes |
| MCRI2_HUMAN | [view interactions] | Low throughput | no | no |
| MCRI1_HUMAN | [view interactions] | Low throughput | no | yes |
| RC3H1_HUMAN | [view interactions] | Low throughput | no | yes |
| LSM1_HUMAN | [view interactions] | Low throughput | no | no |
| UBP2L_HUMAN | [view interactions] | Low throughput | no | yes |
| RO60_HUMAN | [view interactions] | Low throughput | no | yes |
| G3BP1_HUMAN | [view interactions] | Low throughput | no | yes |
| PNRC2_HUMAN | [view interactions] | Low throughput | no | yes |
| RENT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CNOT1_HUMAN | [view interactions] | Low throughput | no | yes |
| LSM4_HUMAN | [view interactions] | Low throughput | no | yes |
| ATX2_HUMAN | [view interactions] | Low throughput | no | yes |
| DCP2_HUMAN | [view interactions] | Low throughput | no | yes |
| DCP1A_HUMAN | [view interactions] | Low throughput | no | yes |
| EDC3_HUMAN | [view interactions] | Low throughput | no | yes |
| AGO2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| EDC4_HUMAN | [view interactions] | Low throughput | no | yes |
| NUFP2_HUMAN | [view interactions] | Low throughput | no | no |
| TNR6A_HUMAN | [view interactions] | Low throughput | no | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX42_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RBM25_HUMAN | [view interactions] | High throughput | no | yes |
| CBX4_HUMAN | [view interactions] | High throughput | no | yes |
| NBDY_HUMAN | [view interactions] | High throughput | no | no |
| SNIP1_HUMAN | [view interactions] | High throughput | no | no |
| ZBT18_HUMAN | [view interactions] | High throughput | no | yes |
| DCA13_HUMAN | [view interactions] | High throughput | no | yes |
| MOT11_HUMAN | [view interactions] | High throughput | no | no |
| AAMDC_HUMAN | [view interactions] | High throughput | no | no |
| RL11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRC8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TAF2_HUMAN | [view interactions] | High throughput | no | no |
| RL19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUF2_HUMAN | [view interactions] | High throughput | no | no |
| RL29_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPOP_HUMAN | [view interactions] | High throughput | no | no |
| RL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UFL1_HUMAN | [view interactions] | High throughput | no | yes |
| RL4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKA3_HUMAN | [view interactions] | High throughput | no | no |
| RL7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| RL7A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDR5_HUMAN | [view interactions] | High throughput | no | no |
| RL8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP4_HUMAN | [view interactions] | High throughput | no | no |
| RLA0_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LIPR2_HUMAN | [view interactions] | High throughput | no | no |
| RS11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NXT1_HUMAN | [view interactions] | High throughput | no | no |
| RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGO4_HUMAN | [view interactions] | High throughput | no | no |
| RS16_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| RS2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| RS23_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DVL2_HUMAN | [view interactions] | High throughput | no | yes |
| RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PSA5_HUMAN | [view interactions] | High throughput | no | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG18_HUMAN | [view interactions] | High throughput | no | yes |
| RS4X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG13_HUMAN | [view interactions] | High throughput | no | no |
| RS6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS24_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| RL23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| RL27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL35_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF4E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RLA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRPC_HUMAN | [view interactions] | High throughput | no | yes |
| RLA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PABP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACE_HUMAN | [view interactions] | High throughput | no | no |
| IF2B3_HUMAN | [view interactions] | High throughput | no | no |
| FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3K_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3G_HUMAN | [view interactions] | High throughput | no | yes |
| ERH_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPR_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRDL_HUMAN | [view interactions] | High throughput | no | yes |
| C1QBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3D_HUMAN | [view interactions] | High throughput | no | yes |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| RS27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF1_HUMAN | [view interactions] | High throughput | no | no |
| LSM12_HUMAN | [view interactions] | High throughput | no | yes |
| RS5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP4_HUMAN | [view interactions] | High throughput | no | yes |
| RL21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATX2L_HUMAN | [view interactions] | High throughput | no | no |
| RL22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DDX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL13A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PABP3_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2A_HUMAN | [view interactions] | High throughput | no | yes |
| RL34_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IF2B_HUMAN | [view interactions] | High throughput | no | yes |
| TR150_HUMAN | [view interactions] | High throughput | no | yes |
| RS12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RTCB_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
| RL31_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ROAA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VCAM1_HUMAN | [view interactions] | High throughput | no | no |
| RS27L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FINC_HUMAN | [view interactions] | High throughput | no | yes |
| EIFCL_HUMAN | [view interactions] | High throughput | no | yes |
| H11_HUMAN | [view interactions] | High throughput | no | no |
| ZN823_HUMAN | [view interactions] | High throughput | no | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL37A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 2ABB_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G3_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MAGT1_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAN3_HUMAN | [view interactions] | High throughput | no | yes |
| MB212_HUMAN | [view interactions] | High throughput | no | no |
| RL17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OASL_HUMAN | [view interactions] | High throughput | no | no |
| SSRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2A_HUMAN | [view interactions] | High throughput | no | no |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HNRPU_HUMAN | [view interactions] | High throughput | no | yes |
| PTPRC_HUMAN | [view interactions] | High throughput | no | no |
| RSSA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHF_HUMAN | [view interactions] | High throughput | no | no |
| RL18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BCL6_HUMAN | [view interactions] | High throughput | no | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CASC3_HUMAN | [view interactions] | High throughput | no | yes |
| RPA49_HUMAN | [view interactions] | High throughput | no | yes |
| RL13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| PRC2C_HUMAN | [view interactions] | High throughput | no | yes |
| SGK1_HUMAN | [view interactions] | High throughput | no | yes |
| RL32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| GNL3_HUMAN | [view interactions] | High throughput | no | yes |
| ASCC2_HUMAN | [view interactions] | High throughput | no | yes |
| PABP2_HUMAN | [view interactions] | High throughput | no | yes |
| H1X_HUMAN | [view interactions] | High throughput | no | yes |
| ILF3_HUMAN | [view interactions] | High throughput | no | yes |
| RS21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LARP1_HUMAN | [view interactions] | High throughput | no | yes |
| RBCC1_HUMAN | [view interactions] | High throughput | no | no |
| ILF2_HUMAN | [view interactions] | High throughput | no | yes |
| ZFR_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| MGN2_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3L_HUMAN | [view interactions] | High throughput | no | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| LN28A_HUMAN | [view interactions] | High throughput | no | no |
| RBM8A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX21_HUMAN | [view interactions] | High throughput | no | yes |
| RL10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| RL36_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTHD1_HUMAN | [view interactions] | High throughput | no | no |
| SP30L_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| AT131_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CEP63_HUMAN | [view interactions] | High throughput | no | yes |
| VAPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CP135_HUMAN | [view interactions] | High throughput | no | no |
| IF2B1_HUMAN | [view interactions] | High throughput | no | no |
| SRPK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F120A_HUMAN | [view interactions] | High throughput | no | yes |
| TRI37_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EIF3I_HUMAN | [view interactions] | High throughput | no | yes |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| ROA0_HUMAN | [view interactions] | High throughput | no | yes |
| ITF2_HUMAN | [view interactions] | High throughput | no | yes |
| ORC2_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF24_HUMAN | [view interactions] | High throughput | no | yes |
| IF4A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KR108_HUMAN | [view interactions] | High throughput | no | no |
| EIF3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TLE5_HUMAN | [view interactions] | High throughput | no | no |
| RS15A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RS25_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| RL27_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKZF1_HUMAN | [view interactions] | High throughput | no | no |
| RS13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUN3A_HUMAN | [view interactions] | High throughput | no | yes |
| RL26L_HUMAN | [view interactions] | High throughput | no | yes |
| K1C40_HUMAN | [view interactions] | High throughput | no | no |
| EIF3B_HUMAN | [view interactions] | High throughput | no | yes |
| VPS52_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS26_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP70_HUMAN | [view interactions] | High throughput | no | yes |
| EIF3E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT8A_HUMAN | [view interactions] | High throughput | no | yes |
| RS20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BIRC7_HUMAN | [view interactions] | High throughput | no | no |
| IF4A1_HUMAN | [view interactions] | High throughput | no | no |
| PNMA5_HUMAN | [view interactions] | High throughput | no | yes |
| RS28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAB2_HUMAN | [view interactions] | High throughput | no | yes |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KRT34_HUMAN | [view interactions] | High throughput | no | no |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| LZTS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RL38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CEP76_HUMAN | [view interactions] | High throughput | no | yes |
| RL10A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI54_HUMAN | [view interactions] | High throughput | no | no |
| RL30_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT14_HUMAN | [view interactions] | High throughput | no | yes |
| KTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ASCC3_HUMAN | [view interactions] | High throughput | no | yes |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FA98A_HUMAN | [view interactions] | High throughput | no | no |
| ZBT43_HUMAN | [view interactions] | High throughput | no | yes |
| SERB1_HUMAN | [view interactions] | High throughput | no | yes |
| GLYC_HUMAN | [view interactions] | High throughput | no | no |
| PAN2_HUMAN | [view interactions] | High throughput | no | no |
| GASP3_HUMAN | [view interactions] | High throughput | no | no |
| RL39_HUMAN | [view interactions] | High throughput | no | no |
| GGYF1_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| EMC9_HUMAN | [view interactions] | High throughput | no | no |
| VINEX_HUMAN | [view interactions] | High throughput | no | no |
| MAP2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| CND2_HUMAN | [view interactions] | High throughput | no | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| PSPC1_HUMAN | [view interactions] | High throughput | no | yes |
| PO6F2_HUMAN | [view interactions] | High throughput | no | no |
| SRP19_HUMAN | [view interactions] | High throughput | no | yes |
| PAK5_HUMAN | [view interactions] | High throughput | no | yes |
| SRP09_HUMAN | [view interactions] | High throughput | no | no |
| EFHC2_HUMAN | [view interactions] | High throughput | no | no |
| LA_HUMAN | [view interactions] | High throughput | no | yes |
| PICK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI31_HUMAN | [view interactions] | High throughput | no | no |
| JKIP1_HUMAN | [view interactions] | High throughput | no | no |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| PLAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| USH1G_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM11_HUMAN | [view interactions] | High throughput | no | no |
| E2F4_HUMAN | [view interactions] | High throughput | no | no |
| SLAI1_HUMAN | [view interactions] | High throughput | no | no |
| TIF1A_HUMAN | [view interactions] | High throughput | no | yes |
| RED_HUMAN | [view interactions] | High throughput | no | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| INKA1_HUMAN | [view interactions] | High throughput | no | no |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| CNKR3_HUMAN | [view interactions] | High throughput | no | yes |
| RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| DAA11_HUMAN | [view interactions] | High throughput | no | no |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MESD_HUMAN | [view interactions] | High throughput | no | yes |
| STK38_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OTUD1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| RCCD1_HUMAN | [view interactions] | High throughput | no | yes |
| ACACA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SP100_HUMAN | [view interactions] | High throughput | no | no |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| TSYL5_HUMAN | [view interactions] | High throughput | no | yes |
| WDR12_HUMAN | [view interactions] | High throughput | no | yes |
| ARBK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG17_HUMAN | [view interactions] | High throughput | no | no |
| CNOT7_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COMD4_HUMAN | [view interactions] | High throughput | no | no |
| SMD3_HUMAN | [view interactions] | High throughput | no | yes |
| LPPRC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| YBOX3_HUMAN | [view interactions] | High throughput | no | yes |
| PPWD1_HUMAN | [view interactions] | High throughput | no | yes |
| DHX9_HUMAN | [view interactions] | High throughput | no | yes |
| TIM13_HUMAN | [view interactions] | High throughput | no | yes |
| NS1BP_HUMAN | [view interactions] | High throughput | no | yes |
| TIM8B_HUMAN | [view interactions] | High throughput | no | yes |
| HS90A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LSM2_HUMAN | [view interactions] | High throughput | no | yes |
| PPIA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ACTS_HUMAN | [view interactions] | High throughput | no | no |
| ETFA_HUMAN | [view interactions] | High throughput | no | yes |
| NECD_HUMAN | [view interactions] | High throughput | no | no |
| SAE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SWAP1_HUMAN | [view interactions] | High throughput | no | no |
| TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| TBA1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENTR1_HUMAN | [view interactions] | High throughput | no | no |
| PRS6A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BEND7_HUMAN | [view interactions] | High throughput | no | no |
| PSA6_HUMAN | [view interactions] | High throughput | no | yes |
| KR103_HUMAN | [view interactions] | High throughput | no | no |
| NUCL_HUMAN | [view interactions] | High throughput | no | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| RL28_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLC4_HUMAN | [view interactions] | High throughput | no | yes |
| GGYF2_HUMAN | [view interactions] | High throughput | no | yes |
| SI1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDIP3_HUMAN | [view interactions] | High throughput | no | no |
| RPGF3_HUMAN | [view interactions] | High throughput | no | yes |
| ROCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| OGT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PYGB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZC21C_HUMAN | [view interactions] | High throughput | no | yes |
| FPPS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CC136_HUMAN | [view interactions] | High throughput | no | yes |
| IDE_HUMAN | [view interactions] | High throughput | no | yes |
| FCHO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SPAT6_HUMAN | [view interactions] | High throughput | no | no |
| AL1B1_HUMAN | [view interactions] | High throughput | no | yes |
| MTUS2_HUMAN | [view interactions] | High throughput | no | yes |
| METK2_HUMAN | [view interactions] | High throughput | no | no |
| HTF4_HUMAN | [view interactions] | High throughput | no | yes |
| GRP75_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
| EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRD16_HUMAN | [view interactions] | High throughput | no | no |
| HCFC1_HUMAN | [view interactions] | High throughput | no | yes |
| ASPP2_HUMAN | [view interactions] | High throughput | no | yes |
| THOP1_HUMAN | [view interactions] | High throughput | no | yes |
| REL_HUMAN | [view interactions] | High throughput | no | yes |
| AP1S1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GTF2I_HUMAN | [view interactions] | High throughput | no | yes |
| CCD14_HUMAN | [view interactions] | High throughput | no | yes |
| CAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZBT10_HUMAN | [view interactions] | High throughput | no | yes |
| PLOD1_HUMAN | [view interactions] | High throughput | no | yes |
| AFF1_HUMAN | [view interactions] | High throughput | no | no |
| FKBP5_HUMAN | [view interactions] | High throughput | no | yes |
| TS101_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLEC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SHIP2_HUMAN | [view interactions] | High throughput | no | yes |
| RBMS2_HUMAN | [view interactions] | High throughput | no | yes |
| UBS3B_HUMAN | [view interactions] | High throughput | no | yes |
| STXB2_HUMAN | [view interactions] | High throughput | no | no |
| AP2M1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX6_HUMAN | [view interactions] | High throughput | no | yes |
| TRXR1_HUMAN | [view interactions] | High throughput | no | yes |
| TADBP_HUMAN | [view interactions] | High throughput | no | yes |
| PREP_HUMAN | [view interactions] | High throughput | no | yes |
| SH3R2_HUMAN | [view interactions] | High throughput | no | yes |
| ARHGG_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| CARL1_HUMAN | [view interactions] | High throughput | no | yes |
| CUL7_HUMAN | [view interactions] | High throughput | no | yes |
| CNDP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
| SPS2_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| PBDC1_HUMAN | [view interactions] | High throughput | no | no |
| PIM1_HUMAN | [view interactions] | High throughput | no | yes |
| CIAO3_HUMAN | [view interactions] | High throughput | no | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| ES8L2_HUMAN | [view interactions] | High throughput | no | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| TRM1_HUMAN | [view interactions] | High throughput | no | yes |
| ROA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYLC_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| DICER_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SGT1_HUMAN | [view interactions] | High throughput | no | no |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| WDTC1_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| FACD2_HUMAN | [view interactions] | High throughput | no | no |
| Z3H7A_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| CELF1_HUMAN | [view interactions] | High throughput | no | yes |
| BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
| CPEB4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
| PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAZL_HUMAN | [view interactions] | High throughput | no | no |
| TRIP4_HUMAN | [view interactions] | High throughput | no | yes |
| AGO1_HUMAN | [view interactions] | High throughput | no | no |
| YAP1_HUMAN | [view interactions] | High throughput | no | yes |
| AGO3_HUMAN | [view interactions] | High throughput | no | yes |
| PPIE_HUMAN | [view interactions] | High throughput | no | yes |
| CNO10_HUMAN | [view interactions] | High throughput | no | yes |
| YAF2_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT2_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT3_HUMAN | [view interactions] | High throughput | no | yes |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| CNOT4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| CNOT9_HUMAN | [view interactions] | High throughput | no | yes |
| MEPCE_HUMAN | [view interactions] | High throughput | no | yes |
| FUBP3_HUMAN | [view interactions] | High throughput | no | yes |
| LZTR1_HUMAN | [view interactions] | High throughput | no | no |
| GTPB1_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| MARF1_HUMAN | [view interactions] | High throughput | no | yes |
| SMG1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| SMG7_HUMAN | [view interactions] | High throughput | no | no |
| SHPS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TDRD3_HUMAN | [view interactions] | High throughput | no | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TM131_HUMAN | [view interactions] | High throughput | no | yes |
| UBP14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNR6B_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| TOP3B_HUMAN | [view interactions] | High throughput | no | no |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| TUT4_HUMAN | [view interactions] | High throughput | no | yes |
| ZN598_HUMAN | [view interactions] | High throughput | no | no |
| TRPV1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IF2B2_HUMAN | [view interactions] | High throughput | no | yes |
| DCP1B_HUMAN | [view interactions] | High throughput | no | yes |
| ATX3_HUMAN | [view interactions] | High throughput | no | yes |
| MEX3B_HUMAN | [view interactions] | High throughput | no | no |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| PUM1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| R3HD2_HUMAN | [view interactions] | High throughput | no | yes |
| YBOX1_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBMS1_HUMAN | [view interactions] | High throughput | no | no |
| LORF1_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| SMAP2_HUMAN | [view interactions] | High throughput | no | yes |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD1_HUMAN | [view interactions] | High throughput | no | no |
| BAG4_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| YTHD2_HUMAN | [view interactions] | High throughput | no | yes |
| TRPM7_HUMAN | [view interactions] | High throughput | no | no |
| BRD7_HUMAN | [view interactions] | High throughput | no | yes |
| YTHD3_HUMAN | [view interactions] | High throughput | no | no |
| MNDA_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| ZCCHV_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| TTP_HUMAN | [view interactions] | High throughput | no | yes |
| RRBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PINK1_HUMAN | [view interactions] | High throughput | no | yes |
| CNO6L_HUMAN | [view interactions] | High throughput | no | no |
| CRKL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PNRC1_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| STING_HUMAN | [view interactions] | High throughput | no | yes |
| NUPR1_HUMAN | [view interactions] | High throughput | no | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| LS14B_HUMAN | [view interactions] | High throughput | no | yes |
| RBM39_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NSRP1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1RA_HUMAN | [view interactions] | High throughput | no | yes |
| MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| URM1_HUMAN | [view interactions] | High throughput | no | yes |
| PR40A_HUMAN | [view interactions] | High throughput | no | no |
| XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPIL4_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| TYY1_HUMAN | [view interactions] | High throughput | no | yes |
| LIMD1_HUMAN | [view interactions] | High throughput | no | yes |
| FA76B_HUMAN | [view interactions] | High throughput | no | no |
| PRP4B_HUMAN | [view interactions] | High throughput | no | yes |
| SAP_HUMAN | [view interactions] | High throughput | no | yes |
| MET17_HUMAN | [view interactions] | High throughput | no | yes |