BEGIN_HUMAN
Evidence for PS localization
Functions
May sustain the structure of the postsynaptic density (PSD). [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in BEGIN_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 30.4348 | 4 | no |
| GO:0046872 | metal ion binding | 30.4348 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in BEGIN_HUMAN |
|---|---|---|---|---|
| GO:0060255 | regulation of macromolecule metabolic process | 56.5217 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 47.8261 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 47.8261 | 4 | no |
| GO:0006996 | organelle organization | 43.4783 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 43.4783 | 5 | no |
| GO:0031323 | regulation of cellular metabolic process | 43.4783 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 43.4783 | 4 | no |
| GO:0010646 | regulation of cell communication | 34.7826 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 34.7826 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 34.7826 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 34.7826 | 5 | no |
| GO:0051049 | regulation of transport | 30.4348 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 30.4348 | 4 | no |
| GO:0010468 | regulation of gene expression | 30.4348 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 30.4348 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 30.4348 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 30.4348 | 5 | no |
| GO:0031399 | regulation of protein modification process | 30.4348 | 6 | no |
| GO:0008104 | protein localization | 26.0870 | 4 | no |
| GO:0009966 | regulation of signal transduction | 26.0870 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 26.0870 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 26.0870 | 5 | no |
| GO:0050890 | cognition | 26.0870 | 4 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 26.0870 | 4 | no |
| GO:0001932 | regulation of protein phosphorylation | 26.0870 | 7 | no |
| GO:0009892 | negative regulation of metabolic process | 26.0870 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 26.0870 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 26.0870 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 26.0870 | 7 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 26.0870 | 5 | no |
| GO:0022607 | cellular component assembly | 26.0870 | 4 | no |
| GO:0045595 | regulation of cell differentiation | 21.7391 | 4 | no |
| GO:0051093 | negative regulation of developmental process | 21.7391 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 21.7391 | 5 | no |
| GO:0009891 | positive regulation of biosynthetic process | 21.7391 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.7391 | 6 | no |
| GO:0010628 | positive regulation of gene expression | 21.7391 | 7 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 21.7391 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 21.7391 | 6 | no |
| GO:0042127 | regulation of cell population proliferation | 21.7391 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.7391 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 21.7391 | 6 | no |
| GO:0071310 | cellular response to organic substance | 21.7391 | 4 | no |
| GO:0016050 | vesicle organization | 21.7391 | 5 | no |
| GO:0043549 | regulation of kinase activity | 21.7391 | 5 | no |
| GO:0045859 | regulation of protein kinase activity | 21.7391 | 6 | no |
| GO:0051338 | regulation of transferase activity | 21.7391 | 4 | no |
| GO:0098657 | import into cell | 21.7391 | 4 | no |
| GO:0030334 | regulation of cell migration | 21.7391 | 5 | no |
| GO:2000145 | regulation of cell motility | 21.7391 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| BEGIN_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| GFI1B_HUMAN | [view interactions] | High throughput | no | no |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HAUS4_HUMAN | [view interactions] | High throughput | no | yes |
| SKA1_HUMAN | [view interactions] | High throughput | no | yes |
| C170L_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EEA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RENR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF15_HUMAN | [view interactions] | High throughput | no | no |
| CE170_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBL1_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| QSOX1_HUMAN | [view interactions] | High throughput | no | no |
| ZN774_HUMAN | [view interactions] | High throughput | no | no |
| ZN417_HUMAN | [view interactions] | High throughput | no | yes |
| ENKD1_HUMAN | [view interactions] | High throughput | no | yes |
| TCHP_HUMAN | [view interactions] | High throughput | no | yes |
| ZN837_HUMAN | [view interactions] | High throughput | no | no |
| ZN319_HUMAN | [view interactions] | High throughput | no | no |
| ZN648_HUMAN | [view interactions] | High throughput | no | no |
| GEM_HUMAN | [view interactions] | High throughput | no | yes |
| DDX6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| F90A1_HUMAN | [view interactions] | High throughput | no | no |
| ZN572_HUMAN | [view interactions] | High throughput | no | yes |
| AQP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PRR35_HUMAN | [view interactions] | High throughput | no | no |
| LENG1_HUMAN | [view interactions] | High throughput | no | no |
| BMP7_HUMAN | [view interactions] | High throughput | no | no |
| RASL3_HUMAN | [view interactions] | High throughput | no | no |
| F161A_HUMAN | [view interactions] | High throughput | no | no |
| GMCL1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN587_HUMAN | [view interactions] | High throughput | no | yes |
| MB213_HUMAN | [view interactions] | High throughput | no | no |
| ATPF2_HUMAN | [view interactions] | High throughput | no | yes |
| CDC23_HUMAN | [view interactions] | High throughput | no | yes |
| SAXO1_HUMAN | [view interactions] | High throughput | no | no |
| ZN835_HUMAN | [view interactions] | High throughput | no | no |
| PRP18_HUMAN | [view interactions] | High throughput | no | yes |
| TRAF4_HUMAN | [view interactions] | High throughput | no | yes |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| RIBC2_HUMAN | [view interactions] | High throughput | no | yes |
| HID1_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BAHD1_HUMAN | [view interactions] | High throughput | no | no |
| DEFI6_HUMAN | [view interactions] | High throughput | no | no |
| ZN250_HUMAN | [view interactions] | High throughput | no | yes |
| CTSR1_HUMAN | [view interactions] | High throughput | no | no |
| K0408_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI27_HUMAN | [view interactions] | High throughput | no | yes |
| HGS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DTNB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| F107A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZF64B_HUMAN | [view interactions] | High throughput | no | no |
| UBP2_HUMAN | [view interactions] | High throughput | no | yes |
| NDC80_HUMAN | [view interactions] | High throughput | no | no |
| HAUS1_HUMAN | [view interactions] | High throughput | no | yes |
| GFOD2_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| GUCD1_HUMAN | [view interactions] | High throughput | no | no |
| KIFC3_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
| KPCZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |