DLGP1_HUMAN
Evidence for PS localization
Functions
Part of the postsynaptic scaffold in neuronal cells. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI004847 | DOC_PP2B_LxvP_1 | DOC | 318 | 321 | - |
| ELMI004542 | LIG_Arc_Nlobe_1 | LIG | 431 | 435 | - |
| ELMI004543 | LIG_Arc_Nlobe_1 | LIG | 483 | 488 | - |
| ELMI004040 | LIG_DLG_GKlike_1 | LIG | 372 | 380 | - |
| ELMI004041 | LIG_DLG_GKlike_1 | LIG | 403 | 411 | - |
| ELMI004847 | DOC_PP2B_LxvP_1 | DOC | 318 | 321 | - |
| ELMI004542 | LIG_Arc_Nlobe_1 | LIG | 431 | 435 | - |
| ELMI004543 | LIG_Arc_Nlobe_1 | LIG | 483 | 488 | - |
| ELMI004040 | LIG_DLG_GKlike_1 | LIG | 372 | 380 | - |
| ELMI004041 | LIG_DLG_GKlike_1 | LIG | 403 | 411 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in DLGP1_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 27.6074 | 4 | no |
| GO:0000166 | nucleotide binding | 23.9264 | 4 | no |
| GO:0017076 | purine nucleotide binding | 23.9264 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 23.9264 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 22.6994 | 4 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in DLGP1_HUMAN |
|---|---|---|---|---|
| GO:0010646 | regulation of cell communication | 56.4417 | 4 | no |
| GO:0048522 | positive regulation of cellular process | 55.8282 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 46.6258 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 42.3313 | 4 | no |
| GO:0009966 | regulation of signal transduction | 39.8773 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 38.6503 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 36.1963 | 4 | no |
| GO:0022607 | cellular component assembly | 35.5828 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 34.9693 | 4 | no |
| GO:0051049 | regulation of transport | 33.1288 | 4 | no |
| GO:0006996 | organelle organization | 31.9018 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 31.9018 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 31.9018 | 4 | no |
| GO:0008104 | protein localization | 31.2883 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 28.8344 | 5 | no |
| GO:0023056 | positive regulation of signaling | 28.8344 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 27.6074 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 26.9939 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 26.9939 | 5 | no |
| GO:0030030 | cell projection organization | 25.7669 | 4 | no |
| GO:0010468 | regulation of gene expression | 25.7669 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.1534 | 5 | no |
| GO:0009893 | positive regulation of metabolic process | 24.5399 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 24.5399 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.5399 | 4 | no |
| GO:1902531 | regulation of intracellular signal transduction | 24.5399 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 23.9264 | 5 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.3129 | 6 | no |
| GO:0051246 | regulation of protein metabolic process | 22.6994 | 5 | no |
| GO:0033043 | regulation of organelle organization | 22.6994 | 5 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 21.4724 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 21.4724 | 4 | no |
| GO:0007010 | cytoskeleton organization | 20.8589 | 5 | no |
| GO:0009967 | positive regulation of signal transduction | 20.8589 | 5 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 20.2454 | 5 | no |
| GO:0099536 | synaptic signaling | 13.4969 | 4 | yes |
| GO:0099537 | trans-synaptic signaling | 13.4969 | 5 | yes |
| GO:0007268 | chemical synaptic transmission | 12.8834 | 7 | yes |
| GO:0098916 | anterograde trans-synaptic signaling | 12.8834 | 6 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DYN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYL2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DYL1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| APC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TANC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MPP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLGP2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| DLG4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MAGI2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DLG2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NHRF3_HUMAN | [view interactions] | Low throughput | no | no |
| SHAN1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRIA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| GRASP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NMDE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SHAN2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SRBS2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| CDK5_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DAB2P_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DEND_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| DIAP1_HUMAN | [view interactions] | High throughput | no | yes |
| DLGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AUXI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DZAN1_HUMAN | [view interactions] | High throughput | no | yes |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| ITSN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITSN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| MAGAB_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NRX1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| NEB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| MYCN_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CRK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCK1_HUMAN | [view interactions] | High throughput | no | yes |
| P85A_HUMAN | [view interactions] | High throughput | no | yes |
| PLCG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPAT7_HUMAN | [view interactions] | High throughput | no | no |
| NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GRIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FBX41_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RACK1_HUMAN | [view interactions] | High throughput | no | yes |
| GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NMDE4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IQGA2_HUMAN | [view interactions] | High throughput | no | yes |
| IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IQEC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IQEC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ITIH4_HUMAN | [view interactions] | High throughput | no | no |
| KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCAB1_HUMAN | [view interactions] | High throughput | no | no |
| KCJ10_HUMAN | [view interactions] | High throughput | no | no |
| KCNJ4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| KIF5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LGI1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRC15_HUMAN | [view interactions] | High throughput | no | no |
| LRRC7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LRRT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPDZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MPRIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDE4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RAP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RPGF4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NGAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEP11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT2_HUMAN | [view interactions] | High throughput | no | no |
| SEPT3_HUMAN | [view interactions] | High throughput | no | no |
| SEPT5_HUMAN | [view interactions] | High throughput | no | no |
| SEPT7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRBS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| T132B_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2N_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBE2O_HUMAN | [view interactions] | High throughput | no | yes |
| WASF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP5_HUMAN | [view interactions] | High throughput | no | no |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| NED4L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNKR3_HUMAN | [view interactions] | High throughput | no | yes |
| HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCNJ1_HUMAN | [view interactions] | High throughput | no | no |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPP6_HUMAN | [view interactions] | High throughput | no | yes |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ADA22_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARF3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARF5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARVC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AGRB2_HUMAN | [view interactions] | High throughput | no | no |
| AGRB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ABTB3_HUMAN | [view interactions] | High throughput | no | no |
| KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSKI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CNTP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CTND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CYH3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |