ABLM1_HUMAN
Evidence for PS localization
Functions
May act as scaffold protein . May play a role in the development of the retina. Has been suggested to play a role in axon guidance. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABLM1_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 32.4675 | 4 | no |
| GO:0019901 | protein kinase binding | 31.1688 | 5 | no |
| GO:0003779 | actin binding | 29.8701 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 25.9740 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 24.6753 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 24.6753 | 4 | no |
| GO:0045296 | cadherin binding | 23.3766 | 4 | no |
| GO:0046872 | metal ion binding | 19.4805 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABLM1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 68.8312 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 61.0390 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 59.7403 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 59.7403 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 58.4416 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 58.4416 | 4 | no |
| GO:0051171 | regulation of nitrogen compound metabolic process | 57.1429 | 4 | no |
| GO:0006996 | organelle organization | 54.5455 | 4 | yes |
| GO:0010646 | regulation of cell communication | 46.7532 | 4 | no |
| GO:0008104 | protein localization | 45.4545 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 44.1558 | 5 | no |
| GO:0007010 | cytoskeleton organization | 42.8571 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 42.8571 | 4 | no |
| GO:0022607 | cellular component assembly | 41.5584 | 4 | yes |
| GO:0010468 | regulation of gene expression | 38.9610 | 5 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 38.9610 | 5 | no |
| GO:0009966 | regulation of signal transduction | 38.9610 | 4 | no |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 37.6623 | 5 | no |
| GO:0033043 | regulation of organelle organization | 35.0649 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 35.0649 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 35.0649 | 5 | no |
| GO:0030030 | cell projection organization | 33.7662 | 4 | yes |
| GO:0051049 | regulation of transport | 32.4675 | 4 | no |
| GO:0009892 | negative regulation of metabolic process | 31.1688 | 4 | no |
| GO:0031344 | regulation of cell projection organization | 31.1688 | 5 | no |
| GO:0031399 | regulation of protein modification process | 31.1688 | 6 | no |
| GO:0071702 | organic substance transport | 31.1688 | 4 | no |
| GO:0120036 | plasma membrane bounded cell projection organization | 29.8701 | 5 | yes |
| GO:0051493 | regulation of cytoskeleton organization | 29.8701 | 6 | no |
| GO:0120035 | regulation of plasma membrane bounded cell projection organization | 29.8701 | 6 | no |
| GO:0009889 | regulation of biosynthetic process | 29.8701 | 4 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 29.8701 | 5 | no |
| GO:0019220 | regulation of phosphate metabolic process | 29.8701 | 6 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 29.8701 | 5 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.5714 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 28.5714 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.5714 | 5 | no |
| GO:0071705 | nitrogen compound transport | 28.5714 | 4 | no |
| GO:0022603 | regulation of anatomical structure morphogenesis | 28.5714 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 27.2727 | 5 | no |
| GO:0032880 | regulation of protein localization | 27.2727 | 5 | no |
| GO:0060341 | regulation of cellular localization | 27.2727 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
| GO:0051172 | negative regulation of nitrogen compound metabolic process | 25.9740 | 5 | no |
| GO:0045595 | regulation of cell differentiation | 25.9740 | 4 | no |
| GO:0042325 | regulation of phosphorylation | 25.9740 | 7 | no |
| GO:0051130 | positive regulation of cellular component organization | 25.9740 | 5 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.6753 | 5 | no |
| GO:0051094 | positive regulation of developmental process | 24.6753 | 4 | no |
| GO:0032970 | regulation of actin filament-based process | 24.6753 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 24.6753 | 4 | no |
| GO:0036211 | protein modification process | 23.3766 | 4 | no |
| GO:0043412 | macromolecule modification | 23.3766 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 23.3766 | 6 | no |
| GO:1903506 | regulation of nucleic acid-templated transcription | 23.3766 | 7 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 23.3766 | 6 | no |
| GO:0001932 | regulation of protein phosphorylation | 23.3766 | 7 | no |
| GO:0015031 | protein transport | 23.3766 | 4 | no |
| GO:0016192 | vesicle-mediated transport | 23.3766 | 4 | no |
| GO:0032956 | regulation of actin cytoskeleton organization | 23.3766 | 5 | no |
| GO:0010647 | positive regulation of cell communication | 23.3766 | 5 | no |
| GO:0023056 | positive regulation of signaling | 23.3766 | 4 | no |
| GO:0031401 | positive regulation of protein modification process | 22.0779 | 7 | no |
| GO:0097435 | supramolecular fiber organization | 22.0779 | 4 | no |
| GO:0050804 | modulation of chemical synaptic transmission | 22.0779 | 5 | no |
| GO:0099177 | regulation of trans-synaptic signaling | 22.0779 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.0779 | 5 | no |
| GO:0051050 | positive regulation of transport | 22.0779 | 4 | no |
| GO:0010941 | regulation of cell death | 22.0779 | 4 | no |
| GO:0071310 | cellular response to organic substance | 20.7792 | 4 | no |
| GO:0043085 | positive regulation of catalytic activity | 20.7792 | 4 | no |
| GO:1902903 | regulation of supramolecular fiber organization | 20.7792 | 5 | no |
| GO:0010562 | positive regulation of phosphorus metabolic process | 20.7792 | 6 | no |
| GO:0045937 | positive regulation of phosphate metabolic process | 20.7792 | 7 | no |
| GO:0030031 | cell projection assembly | 15.5844 | 5 | yes |
| GO:0070925 | organelle assembly | 15.5844 | 5 | yes |
| GO:0120031 | plasma membrane bounded cell projection assembly | 12.9870 | 6 | yes |
| GO:0030032 | lamellipodium assembly | 5.1948 | 7 | yes |
| GO:0044782 | cilium organization | 5.1948 | 5 | yes |
| GO:0060271 | cilium assembly | 5.1948 | 6 | yes |
| GO:0097581 | lamellipodium organization | 5.1948 | 6 | yes |
Disease
| Term | Name | % | Distance from top the of the tree | Annotated in ABLM1_HUMAN |
|---|---|---|---|---|
| DOID:331 | central nervous system disease | 2.5974 | 3 | no |
| DOID:936 | brain disease | 2.5974 | 4 | no |
| DOID:114 | heart disease | 2.5974 | 3 | no |
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| ABRA_HUMAN | [view interactions] | Low throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CBY1_HUMAN | [view interactions] | High throughput | no | no |
| FHL2_HUMAN | [view interactions] | High throughput | no | yes |
| HSF2B_HUMAN | [view interactions] | High throughput | no | yes |
| CCD57_HUMAN | [view interactions] | High throughput | no | yes |
| KCJ12_HUMAN | [view interactions] | High throughput | no | no |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ASB18_HUMAN | [view interactions] | High throughput | no | no |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| SUZ12_HUMAN | [view interactions] | High throughput | no | no |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| LUZP4_HUMAN | [view interactions] | High throughput | no | no |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| NMT1_HUMAN | [view interactions] | High throughput | no | yes |
| SPCS_HUMAN | [view interactions] | High throughput | no | no |
| LIN7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDK2_HUMAN | [view interactions] | High throughput | no | yes |
| FLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MYO1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO19_HUMAN | [view interactions] | High throughput | no | yes |
| MY18A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| COR1C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NEUFC_HUMAN | [view interactions] | High throughput | no | yes |
| KLH40_HUMAN | [view interactions] | High throughput | no | no |
| BCDO1_HUMAN | [view interactions] | High throughput | no | no |
| MED21_HUMAN | [view interactions] | High throughput | no | yes |
| CYLD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
| DX39B_HUMAN | [view interactions] | High throughput | no | no |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| RNF6_HUMAN | [view interactions] | High throughput | no | no |
| MEP50_HUMAN | [view interactions] | High throughput | no | yes |
| RNF4_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| CDK9_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| VAV_HUMAN | [view interactions] | High throughput | no | no |
| ARHG6_HUMAN | [view interactions] | High throughput | no | no |
| DOCK8_HUMAN | [view interactions] | High throughput | no | yes |
| VAV2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CHM4C_HUMAN | [view interactions] | High throughput | no | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| KI20A_HUMAN | [view interactions] | High throughput | no | yes |
| NPC1_HUMAN | [view interactions] | High throughput | no | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| ADAT3_HUMAN | [view interactions] | High throughput | no | no |
| SH21B_HUMAN | [view interactions] | High throughput | no | no |
| KIBRA_HUMAN | [view interactions] | High throughput | no | yes |
| APBA1_HUMAN | [view interactions] | High throughput | no | no |
| MPP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| SNX27_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DAPK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| MFHA1_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| PDLI5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MOONR_HUMAN | [view interactions] | High throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TERA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CK052_HUMAN | [view interactions] | High throughput | no | no |
| E41LA_HUMAN | [view interactions] | High throughput | no | yes |
| EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FLOT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GFAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARCS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| OCLN_HUMAN | [view interactions] | High throughput | no | no |
| PROF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PERI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PAXI_HUMAN | [view interactions] | High throughput | no | yes |
| RADI_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
| STX7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNE3_HUMAN | [view interactions] | High throughput | no | no |
| TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NAA40_HUMAN | [view interactions] | High throughput | no | no |
| VP33B_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IFM1_HUMAN | [view interactions] | High throughput | no | no |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| IFM3_HUMAN | [view interactions] | High throughput | no | yes |
| PML_HUMAN | [view interactions] | High throughput | no | yes |
| RNF43_HUMAN | [view interactions] | High throughput | no | yes |
| DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZMYM1_HUMAN | [view interactions] | High throughput | no | no |
| PP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF1C_HUMAN | [view interactions] | High throughput | no | yes |
| MYH9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| FLOT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FLNB_HUMAN | [view interactions] | High throughput | no | no |
| LIMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CALL3_HUMAN | [view interactions] | High throughput | no | yes |
| COBL1_HUMAN | [view interactions] | High throughput | no | yes |
| TMOD3_HUMAN | [view interactions] | High throughput | no | yes |
| TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PFD3_HUMAN | [view interactions] | High throughput | no | yes |
| DREB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MARE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYH10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PDLI7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SEPT9_HUMAN | [view interactions] | High throughput | no | no |
| IQGA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NCBP2_HUMAN | [view interactions] | High throughput | no | yes |
| CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LDOC1_HUMAN | [view interactions] | High throughput | no | no |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMPA2_HUMAN | [view interactions] | High throughput | no | no |
| CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CARD9_HUMAN | [view interactions] | High throughput | no | no |
| VIME_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TRAF2_HUMAN | [view interactions] | High throughput | no | yes |
| T22D4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| USBP1_HUMAN | [view interactions] | High throughput | no | no |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| K1C15_HUMAN | [view interactions] | High throughput | no | no |
| SRBP2_HUMAN | [view interactions] | High throughput | no | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| PTPRD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| EGLN_HUMAN | [view interactions] | High throughput | no | no |
| TITIN_HUMAN | [view interactions] | High throughput | no | no |
| ODFP2_HUMAN | [view interactions] | High throughput | no | no |
| CE128_HUMAN | [view interactions] | High throughput | no | yes |
| FBF1_HUMAN | [view interactions] | High throughput | no | no |
| CEP19_HUMAN | [view interactions] | High throughput | no | no |
| CEP89_HUMAN | [view interactions] | High throughput | no | no |
| NINL_HUMAN | [view interactions] | High throughput | no | yes |
| STIL_HUMAN | [view interactions] | High throughput | no | no |
| SCLT1_HUMAN | [view interactions] | High throughput | no | yes |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| ADIP_HUMAN | [view interactions] | High throughput | no | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| FGFR1_HUMAN | [view interactions] | High throughput | no | yes |
| FGFR4_HUMAN | [view interactions] | High throughput | no | no |
| ABLM3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAC3_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| RAC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |