ABLM1_HUMAN
Evidence for PS localization
Functions
May act as scaffold protein . May play a role in the development of the retina. Has been suggested to play a role in axon guidance. [View more on UniProt]
Protein features
Transmembrane
Phase separation
ELM
Phosphorylation
PFAM
Coiled coil
Anchor
Disordered
Interacting regions
Sequence
LOADING 55%
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Interacting regions
Canonical [ABLM1_HUMAN]
Isoform [F8W8M4] alignment
Isoform [H0Y7N6] alignment
Isoform [B7Z4H1] alignment
Isoform [A0A9L9PY99] alignment
Isoform [F6XFR5] alignment
Isoform [A0A494C1P1] alignment
Isoform [A0A3B3IS55] alignment
Isoform [O14639-2] alignment
Isoform [O14639-3] alignment
Isoform [O14639-4] alignment
Isoform [O14639-5] alignment
Isoform [O14639-6] alignment
LOADING 23%
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in ABLM1_HUMAN |
|---|---|---|---|---|
| GO:0019900 | kinase binding | 31.7647 | 4 | no |
| GO:0003779 | actin binding | 28.2353 | 4 | yes |
| GO:0019901 | protein kinase binding | 27.0588 | 5 | no |
| GO:0000166 | nucleotide binding | 25.8824 | 4 | no |
| GO:0017076 | purine nucleotide binding | 25.8824 | 5 | no |
| GO:0043168 | anion binding | 25.8824 | 4 | no |
| GO:0045296 | cadherin binding | 24.7059 | 4 | no |
| GO:0030554 | adenyl nucleotide binding | 23.5294 | 6 | no |
| GO:0032555 | purine ribonucleotide binding | 23.5294 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 23.5294 | 4 | no |
| GO:0003723 | RNA binding | 23.5294 | 4 | no |
| GO:0043169 | cation binding | 22.3529 | 4 | yes |
| GO:0046872 | metal ion binding | 22.3529 | 5 | yes |
| GO:0005524 | ATP binding | 21.1765 | 5 | no |
| GO:0032559 | adenyl ribonucleotide binding | 21.1765 | 5 | no |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in ABLM1_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 69.4118 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 65.8824 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 64.7059 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 63.5294 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 61.1765 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 60.0000 | 4 | no |
| GO:0010646 | regulation of cell communication | 52.9412 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 49.4118 | 4 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 48.2353 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 48.2353 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 47.0588 | 5 | no |
| GO:0010468 | regulation of gene expression | 47.0588 | 6 | no |
| GO:0006996 | organelle organization | 45.8824 | 4 | yes |
| GO:0009966 | regulation of signal transduction | 44.7059 | 4 | no |
| GO:0008104 | protein localization | 43.5294 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 43.5294 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 41.1765 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 41.1765 | 5 | no |
| GO:0022607 | cellular component assembly | 40.0000 | 4 | yes |
| GO:0009892 | negative regulation of metabolic process | 37.6471 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 35.2941 | 5 | no |
| GO:1902531 | regulation of intracellular signal transduction | 35.2941 | 5 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 35.2941 | 5 | no |
| GO:0031399 | regulation of protein modification process | 34.1176 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 34.1176 | 4 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| 1433B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433F_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A16L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABCE1_HUMAN | [view interactions] | High throughput | no | yes |
| ABLM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ABRA_HUMAN | [view interactions] | Low throughput | no | no |
| ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ADAT3_HUMAN | [view interactions] | High throughput | no | no |
| ADIP_HUMAN | [view interactions] | High throughput | no | yes |
| ANLN_HUMAN | [view interactions] | High throughput | no | yes |
| APBA1_HUMAN | [view interactions] | High throughput | no | no |
| ARHG6_HUMAN | [view interactions] | High throughput | no | no |
| ASB18_HUMAN | [view interactions] | High throughput | no | no |
| B2CL1_HUMAN | [view interactions] | High throughput | no | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BCDO1_HUMAN | [view interactions] | High throughput | no | no |
| BEGIN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BTF3_HUMAN | [view interactions] | High throughput | no | yes |
| CACO2_HUMAN | [view interactions] | High throughput | no | yes |