TNIK_HUMAN
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322. [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in TNIK_HUMAN |
---|---|---|---|---|
GO:0043168 | anion binding | 31.2268 | 4 | yes |
GO:0000166 | nucleotide binding | 28.6245 | 4 | yes |
GO:0017076 | purine nucleotide binding | 28.2528 | 5 | yes |
GO:0032555 | purine ribonucleotide binding | 27.5093 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 25.2788 | 4 | yes |
GO:0030554 | adenyl nucleotide binding | 24.5353 | 6 | yes |
GO:0043169 | cation binding | 24.1636 | 4 | no |
GO:0046872 | metal ion binding | 24.1636 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 23.7918 | 5 | yes |
GO:0005524 | ATP binding | 21.5613 | 5 | yes |
GO:0016301 | kinase activity | 13.0112 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 11.8959 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 8.5502 | 4 | yes |
GO:0106310 | protein serine kinase activity | 8.1784 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in TNIK_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 55.3903 | 4 | yes |
GO:0010646 | regulation of cell communication | 51.3011 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 45.7249 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 45.3532 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 43.8662 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 41.6357 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 40.1487 | 4 | yes |
GO:0009966 | regulation of signal transduction | 39.4052 | 4 | yes |
GO:0022607 | cellular component assembly | 34.2007 | 4 | yes |
GO:0006996 | organelle organization | 33.8290 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 31.9703 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 31.9703 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 31.9703 | 5 | no |
GO:0010468 | regulation of gene expression | 31.2268 | 6 | no |
GO:0009893 | positive regulation of metabolic process | 30.8550 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 30.8550 | 5 | yes |
GO:0008104 | protein localization | 29.7398 | 4 | yes |
GO:0010604 | positive regulation of macromolecule metabolic process | 29.3680 | 5 | yes |
GO:0051049 | regulation of transport | 28.2528 | 4 | no |
GO:0023056 | positive regulation of signaling | 26.7658 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 26.7658 | 4 | no |
GO:0010647 | positive regulation of cell communication | 26.3941 | 5 | yes |
GO:1902531 | regulation of intracellular signal transduction | 26.0223 | 5 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 25.6506 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 25.6506 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 25.2788 | 5 | yes |
GO:0010605 | negative regulation of macromolecule metabolic process | 25.2788 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 23.4201 | 4 | yes |
GO:0051130 | positive regulation of cellular component organization | 23.4201 | 5 | no |
GO:0031324 | negative regulation of cellular metabolic process | 23.0483 | 5 | no |
GO:0031344 | regulation of cell projection organization | 23.0483 | 5 | yes |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 22.6766 | 6 | yes |
GO:0044087 | regulation of cellular component biogenesis | 21.9331 | 4 | no |
GO:0031399 | regulation of protein modification process | 21.5613 | 6 | yes |
GO:0007010 | cytoskeleton organization | 21.1896 | 5 | yes |
GO:0030030 | cell projection organization | 21.1896 | 4 | yes |
GO:0051247 | positive regulation of protein metabolic process | 21.1896 | 6 | yes |
GO:0033043 | regulation of organelle organization | 20.4461 | 5 | no |
GO:0006796 | phosphate-containing compound metabolic process | 20.4461 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 20.4461 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 20.4461 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 19.3309 | 6 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 19.3309 | 5 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 18.9591 | 4 | yes |
GO:0036211 | protein modification process | 18.9591 | 4 | yes |
GO:0043412 | macromolecule modification | 18.9591 | 4 | yes |
GO:0010975 | regulation of neuron projection development | 17.8439 | 7 | yes |
GO:0001932 | regulation of protein phosphorylation | 17.4721 | 7 | yes |
GO:0042325 | regulation of phosphorylation | 17.4721 | 7 | yes |
GO:0120036 | plasma membrane bounded cell projection organization | 16.7286 | 5 | yes |
GO:0016310 | phosphorylation | 13.7546 | 5 | yes |
GO:0031401 | positive regulation of protein modification process | 13.7546 | 7 | yes |
GO:0141124 | intracellular signaling cassette | 13.7546 | 4 | yes |
GO:0010562 | positive regulation of phosphorus metabolic process | 12.6394 | 6 | yes |
GO:0045937 | positive regulation of phosphate metabolic process | 12.6394 | 7 | yes |
GO:0001934 | positive regulation of protein phosphorylation | 11.8959 | 8 | yes |
GO:0042327 | positive regulation of phosphorylation | 11.8959 | 8 | yes |
GO:0010243 | response to organonitrogen compound | 11.5242 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 11.1524 | 6 | yes |
GO:0043408 | regulation of MAPK cascade | 10.7807 | 6 | yes |
GO:0072657 | protein localization to membrane | 10.7807 | 4 | yes |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 10.4089 | 4 | yes |
GO:0006468 | protein phosphorylation | 10.0372 | 5 | yes |
GO:0048812 | neuron projection morphogenesis | 10.0372 | 5 | yes |
GO:1990778 | protein localization to cell periphery | 6.6914 | 5 | yes |
GO:0030031 | cell projection assembly | 6.3197 | 5 | yes |
GO:0050773 | regulation of dendrite development | 6.3197 | 4 | yes |
GO:0043410 | positive regulation of MAPK cascade | 5.9480 | 7 | yes |
GO:0072659 | protein localization to plasma membrane | 5.9480 | 5 | yes |
GO:0048814 | regulation of dendrite morphogenesis | 5.5762 | 5 | yes |
GO:0000165 | MAPK cascade | 5.2045 | 5 | yes |
GO:0016055 | Wnt signaling pathway | 5.2045 | 4 | yes |
GO:0120031 | plasma membrane bounded cell projection assembly | 5.2045 | 6 | yes |
GO:0046777 | protein autophosphorylation | 4.8327 | 6 | yes |
GO:0046328 | regulation of JNK cascade | 2.9740 | 7 | yes |
GO:0032528 | microvillus organization | 1.8587 | 6 | yes |
GO:0046330 | positive regulation of JNK cascade | 1.8587 | 8 | yes |
GO:0030033 | microvillus assembly | 1.4870 | 7 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
NEDD4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TNIK_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
STK26_HUMAN | [view interactions] | Low throughput | no | no |
M3K7_HUMAN | [view interactions] | Low throughput | no | yes |
TAB2_HUMAN | [view interactions] | Low throughput | no | yes |
IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TANC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TF7L2_HUMAN | [view interactions] | Low throughput | no | yes |
TRAF2_HUMAN | [view interactions] | Low throughput | no | yes |
CBR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
WIZ_HUMAN | [view interactions] | High throughput | no | yes |
DEST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZC3H4_HUMAN | [view interactions] | High throughput | no | yes |
RM14_HUMAN | [view interactions] | High throughput | no | yes |
ZEB2_HUMAN | [view interactions] | High throughput | no | yes |
TR112_HUMAN | [view interactions] | High throughput | no | yes |
ZN219_HUMAN | [view interactions] | High throughput | no | yes |
KCY_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN462_HUMAN | [view interactions] | High throughput | no | no |
IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
ZIC2_HUMAN | [view interactions] | High throughput | no | no |
UCHL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZMYM2_HUMAN | [view interactions] | High throughput | no | yes |
CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SODM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BMI1_HUMAN | [view interactions] | High throughput | no | yes |
FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FRY_HUMAN | [view interactions] | High throughput | no | yes |
ARP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BORC5_HUMAN | [view interactions] | High throughput | no | yes |
RT16_HUMAN | [view interactions] | High throughput | no | yes |
DCTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
DDX5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SET_HUMAN | [view interactions] | High throughput | no | yes |
DPYL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GLRX3_HUMAN | [view interactions] | High throughput | no | yes |
ZC3H1_HUMAN | [view interactions] | High throughput | no | yes |
SERC_HUMAN | [view interactions] | High throughput | no | yes |
PPM1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CPEB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PCBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NINL_HUMAN | [view interactions] | High throughput | no | yes |
TEAD3_HUMAN | [view interactions] | High throughput | no | no |
LRCH1_HUMAN | [view interactions] | High throughput | no | yes |
RU2B_HUMAN | [view interactions] | High throughput | no | yes |
PLCL2_HUMAN | [view interactions] | High throughput | no | yes |
EIF3M_HUMAN | [view interactions] | High throughput | no | yes |
GSE1_HUMAN | [view interactions] | High throughput | no | yes |
EIF3H_HUMAN | [view interactions] | High throughput | no | yes |
CBPC1_HUMAN | [view interactions] | High throughput | no | yes |
PPIH_HUMAN | [view interactions] | High throughput | no | yes |
UBP24_HUMAN | [view interactions] | High throughput | no | yes |
LYAR_HUMAN | [view interactions] | High throughput | no | no |
SMHD1_HUMAN | [view interactions] | High throughput | no | yes |
NUDC_HUMAN | [view interactions] | High throughput | no | yes |
SIR1_HUMAN | [view interactions] | High throughput | no | yes |
RUVB2_HUMAN | [view interactions] | High throughput | no | yes |
GLCE_HUMAN | [view interactions] | High throughput | no | yes |
LRC59_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANR17_HUMAN | [view interactions] | High throughput | no | yes |
RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GATM_HUMAN | [view interactions] | High throughput | no | no |
CYC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BEX3_HUMAN | [view interactions] | High throughput | no | yes |
SIAS_HUMAN | [view interactions] | High throughput | no | yes |
TIAM2_HUMAN | [view interactions] | High throughput | no | yes |
CYBP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCLO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THIL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOGA4_HUMAN | [view interactions] | High throughput | no | yes |
C1TC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPF_HUMAN | [view interactions] | High throughput | no | yes |
SYSC_HUMAN | [view interactions] | High throughput | no | yes |
LUZP2_HUMAN | [view interactions] | High throughput | no | yes |
PRS4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAP31_HUMAN | [view interactions] | High throughput | no | yes |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KPRA_HUMAN | [view interactions] | High throughput | no | no |
NFL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT4_HUMAN | [view interactions] | High throughput | no | no |
NUP98_HUMAN | [view interactions] | High throughput | no | no |
ITF2_HUMAN | [view interactions] | High throughput | no | yes |
LIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYFP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRBN_HUMAN | [view interactions] | High throughput | no | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
THAP4_HUMAN | [view interactions] | High throughput | no | yes |
HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
UBR5_HUMAN | [view interactions] | High throughput | no | no |
HERC2_HUMAN | [view interactions] | High throughput | no | yes |
SNX7_HUMAN | [view interactions] | High throughput | no | yes |
MYCB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ATRX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCKP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIF1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ABI1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KANL2_HUMAN | [view interactions] | High throughput | no | yes |
ABI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UACA_HUMAN | [view interactions] | High throughput | no | yes |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STRAB_HUMAN | [view interactions] | High throughput | no | no |
RHG32_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
YETS2_HUMAN | [view interactions] | High throughput | no | no |
RHG39_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WWC3_HUMAN | [view interactions] | High throughput | no | yes |
ARHG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CENPJ_HUMAN | [view interactions] | High throughput | no | no |
BCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRS7_HUMAN | [view interactions] | High throughput | no | yes |
BIN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZN248_HUMAN | [view interactions] | High throughput | no | yes |
CACO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHOT1_HUMAN | [view interactions] | High throughput | no | no |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AN36B_HUMAN | [view interactions] | High throughput | no | no |
KCC2B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PTN11_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCC2D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNX6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KCC2G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI27_HUMAN | [view interactions] | High throughput | no | yes |
CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDF6_HUMAN | [view interactions] | High throughput | no | yes |
CAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMCE1_HUMAN | [view interactions] | High throughput | no | yes |
CSKP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SNPC4_HUMAN | [view interactions] | High throughput | no | no |
CAD10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SON_HUMAN | [view interactions] | High throughput | no | yes |
CADH2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
CE170_HUMAN | [view interactions] | High throughput | no | yes |
STAT2_HUMAN | [view interactions] | High throughput | no | yes |
C170B_HUMAN | [view interactions] | High throughput | no | yes |
ACTG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CN37_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SMC6_HUMAN | [view interactions] | High throughput | no | no |
CTNA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPC1_HUMAN | [view interactions] | High throughput | no | yes |
CTND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
BRCC3_HUMAN | [view interactions] | High throughput | no | no |
CTND2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
WDR26_HUMAN | [view interactions] | High throughput | no | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EDEM3_HUMAN | [view interactions] | High throughput | no | yes |
DCLK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DHX16_HUMAN | [view interactions] | High throughput | no | yes |
DGKI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UBP32_HUMAN | [view interactions] | High throughput | no | yes |
DLG1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCOA1_HUMAN | [view interactions] | High throughput | no | yes |
DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BECN1_HUMAN | [view interactions] | High throughput | no | yes |
DYN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DZIP3_HUMAN | [view interactions] | High throughput | no | yes |
DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCOR1_HUMAN | [view interactions] | High throughput | no | yes |
ERC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CE350_HUMAN | [view interactions] | High throughput | no | yes |
GELS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TATD2_HUMAN | [view interactions] | High throughput | no | yes |
GIT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KDM4A_HUMAN | [view interactions] | High throughput | no | yes |
GLNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TMM17_HUMAN | [view interactions] | High throughput | no | yes |
HCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EZRI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AINX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LAMP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IQEC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
KIF2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EPHA5_HUMAN | [view interactions] | High throughput | no | no |
KIF2C_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EPHA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LRRC7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EPHB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MTSS2_HUMAN | [view interactions] | High throughput | no | yes |
FGFR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGFR4_HUMAN | [view interactions] | High throughput | no | no |
NSF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NTRK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAK5_HUMAN | [view interactions] | High throughput | no | yes |
ROR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCDH8_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STYK1_HUMAN | [view interactions] | High throughput | no | yes |
PEX5R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
PKHA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCNK3_HUMAN | [view interactions] | High throughput | no | no |
PP2AB_HUMAN | [view interactions] | High throughput | no | yes |
TNKS1_HUMAN | [view interactions] | High throughput | no | yes |
KAPCA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SOS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KPCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNR3_HUMAN | [view interactions] | High throughput | no | yes |
KPCG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KBTB7_HUMAN | [view interactions] | High throughput | no | yes |
PTPRD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
I20RA_HUMAN | [view interactions] | High throughput | no | no |
PTPRS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RT11_HUMAN | [view interactions] | High throughput | no | yes |
PURA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UBE2A_HUMAN | [view interactions] | High throughput | no | no |
RPGF4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
RIMB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
RIMS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RIGI_HUMAN | [view interactions] | High throughput | no | yes |
SKT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRIM9_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MTCL3_HUMAN | [view interactions] | High throughput | no | no |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
SPTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INT14_HUMAN | [view interactions] | High throughput | no | yes |
SPTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MVP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TANC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FNTA_HUMAN | [view interactions] | High throughput | no | yes |
TAOK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANR50_HUMAN | [view interactions] | High throughput | no | no |
TENR_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
INT13_HUMAN | [view interactions] | High throughput | no | no |
TP53B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BEND3_HUMAN | [view interactions] | High throughput | no | yes |
TPR_HUMAN | [view interactions] | High throughput | no | yes |
INT10_HUMAN | [view interactions] | High throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
SLMAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRIM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
INSY1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI46_HUMAN | [view interactions] | High throughput | no | no |
KCNE3_HUMAN | [view interactions] | High throughput | no | yes |
USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BEX1_HUMAN | [view interactions] | High throughput | no | yes |
WASF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPCS3_HUMAN | [view interactions] | High throughput | no | yes |
ZSC18_HUMAN | [view interactions] | High throughput | no | yes |
PLCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ABLM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCL3_HUMAN | [view interactions] | High throughput | no | no |
ANK3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAP2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AP2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KXDL1_HUMAN | [view interactions] | High throughput | no | yes |
AP2A2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAG2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAC1A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SMUF1_HUMAN | [view interactions] | High throughput | no | yes |
CA2D1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
CACB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD8_HUMAN | [view interactions] | High throughput | no | yes |
CACB4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CEP63_HUMAN | [view interactions] | High throughput | no | yes |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CLAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DLG2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RASN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DC1L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DZAN1_HUMAN | [view interactions] | High throughput | no | yes |
HOOK1_HUMAN | [view interactions] | High throughput | no | no |
GRIA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BICD1_HUMAN | [view interactions] | High throughput | no | yes |
GRIA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BICD2_HUMAN | [view interactions] | High throughput | no | yes |
GRIA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GTPB1_HUMAN | [view interactions] | High throughput | no | yes |
GRIK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJC2_HUMAN | [view interactions] | High throughput | no | yes |
NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS12B_HUMAN | [view interactions] | High throughput | no | yes |
NMDE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARF6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CK052_HUMAN | [view interactions] | High throughput | no | no |
GRM5_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAV1_HUMAN | [view interactions] | High throughput | no | no |
IQEC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CTNA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IQEC3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CXAR_HUMAN | [view interactions] | High throughput | no | yes |
KALRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CXA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCMA1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LZTS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LZTS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OCLN_HUMAN | [view interactions] | High throughput | no | no |
MACF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MAGI2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NAA40_HUMAN | [view interactions] | High throughput | no | no |
PALS1_HUMAN | [view interactions] | High throughput | no | no |
TOLIP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NBEA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDKL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCNQ2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NED4L_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NTRK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NGEF_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
NLGN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
NCK1_HUMAN | [view interactions] | High throughput | no | yes |
PP1G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
AKAP9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MUC18_HUMAN | [view interactions] | High throughput | no | yes |
ANK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SEPT3_HUMAN | [view interactions] | High throughput | no | no |
CLUS_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNKR2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SHAN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYST_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HARS1_HUMAN | [view interactions] | High throughput | no | yes |
SHSA7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KIBRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SI1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYT1L_HUMAN | [view interactions] | High throughput | no | no |
AP180_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCOR2_HUMAN | [view interactions] | High throughput | no | yes |
SRBS2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NFM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYNE1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ASPP1_HUMAN | [view interactions] | High throughput | no | yes |
ZO1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SPTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UN13A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SRGP3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ADNP_HUMAN | [view interactions] | High throughput | no | yes |
TRIM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGRIN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
APC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RHG21_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BC11B_HUMAN | [view interactions] | High throughput | no | yes |
BRD7_HUMAN | [view interactions] | High throughput | no | yes |
CABIN_HUMAN | [view interactions] | High throughput | no | yes |
XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ERO1A_HUMAN | [view interactions] | High throughput | no | yes |
CAPR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CARM1_HUMAN | [view interactions] | High throughput | no | yes |
CCAR2_HUMAN | [view interactions] | High throughput | no | yes |
CDC73_HUMAN | [view interactions] | High throughput | no | yes |
CHD8_HUMAN | [view interactions] | High throughput | no | no |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CTBP2_HUMAN | [view interactions] | High throughput | no | no |
STRN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PCD16_HUMAN | [view interactions] | High throughput | no | yes |
CEP43_HUMAN | [view interactions] | High throughput | no | no |
DCX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
DDX3X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DOC11_HUMAN | [view interactions] | High throughput | no | yes |
LONM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DOCK7_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
STRN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DYHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CACO2_HUMAN | [view interactions] | High throughput | no | yes |
EDC4_HUMAN | [view interactions] | High throughput | no | yes |
DCTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
2A5D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KGP1_HUMAN | [view interactions] | High throughput | no | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
PCM1_HUMAN | [view interactions] | High throughput | no | yes |
EHMT1_HUMAN | [view interactions] | High throughput | no | yes |
KIF7_HUMAN | [view interactions] | High throughput | no | yes |
EHMT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CCD92_HUMAN | [view interactions] | High throughput | no | yes |
EPMIP_HUMAN | [view interactions] | High throughput | no | no |
FKB15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
STRP1_HUMAN | [view interactions] | High throughput | no | yes |
FBSP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CAVN1_HUMAN | [view interactions] | High throughput | no | no |
FOXP2_HUMAN | [view interactions] | High throughput | no | yes |
HOME1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GLT13_HUMAN | [view interactions] | High throughput | no | no |
FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
MISSL_HUMAN | [view interactions] | High throughput | no | yes |
P66B_HUMAN | [view interactions] | High throughput | no | yes |
CTTB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GSK3B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RANB9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GTPB4_HUMAN | [view interactions] | High throughput | no | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
HDAC2_HUMAN | [view interactions] | High throughput | no | yes |
SIKE1_HUMAN | [view interactions] | High throughput | no | yes |
HIRA_HUMAN | [view interactions] | High throughput | no | yes |
MMTA2_HUMAN | [view interactions] | High throughput | no | yes |
HOME3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDEL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCTD9_HUMAN | [view interactions] | High throughput | no | no |
CPVL_HUMAN | [view interactions] | High throughput | no | no |
KDM1A_HUMAN | [view interactions] | High throughput | no | yes |
STRN4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KIF5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FGOP2_HUMAN | [view interactions] | High throughput | no | yes |
KINH_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NDE1_HUMAN | [view interactions] | High throughput | no | yes |
KIF5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CT2NL_HUMAN | [view interactions] | High throughput | no | yes |
LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHOCN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LMNB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RANG_HUMAN | [view interactions] | High throughput | no | no |
LSG1_HUMAN | [view interactions] | High throughput | no | yes |
BUB3_HUMAN | [view interactions] | High throughput | no | yes |
MAGD2_HUMAN | [view interactions] | High throughput | no | yes |
FKBP3_HUMAN | [view interactions] | High throughput | no | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
THIC_HUMAN | [view interactions] | High throughput | no | yes |
MATR3_HUMAN | [view interactions] | High throughput | no | yes |
PSA2_HUMAN | [view interactions] | High throughput | no | yes |
MGAP_HUMAN | [view interactions] | High throughput | no | yes |
STRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MSD2_HUMAN | [view interactions] | High throughput | no | yes |
AATM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYO5A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ROA3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NAT10_HUMAN | [view interactions] | High throughput | no | yes |
ML12A_HUMAN | [view interactions] | High throughput | no | no |
NEST_HUMAN | [view interactions] | High throughput | no | no |
SF3B6_HUMAN | [view interactions] | High throughput | no | yes |
NEUL4_HUMAN | [view interactions] | High throughput | no | yes |
DHSO_HUMAN | [view interactions] | High throughput | no | no |
NOP56_HUMAN | [view interactions] | High throughput | no | yes |
RS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PAF1_HUMAN | [view interactions] | High throughput | no | yes |
DHCR7_HUMAN | [view interactions] | High throughput | no | yes |
PP2BB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSMD6_HUMAN | [view interactions] | High throughput | no | yes |
KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AATC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRC2B_HUMAN | [view interactions] | High throughput | no | no |
PIMT_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCOR1_HUMAN | [view interactions] | High throughput | no | yes |
EMC1_HUMAN | [view interactions] | High throughput | no | yes |
RCOR2_HUMAN | [view interactions] | High throughput | no | no |
PDCD5_HUMAN | [view interactions] | High throughput | no | yes |
SNUT1_HUMAN | [view interactions] | High throughput | no | yes |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
2AAA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RCC2_HUMAN | [view interactions] | High throughput | no | no |
SH3G2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPAC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SMRC2_HUMAN | [view interactions] | High throughput | no | yes |
PSD13_HUMAN | [view interactions] | High throughput | no | yes |
SP16H_HUMAN | [view interactions] | High throughput | no | yes |
PCBP3_HUMAN | [view interactions] | High throughput | no | yes |
SYNE2_HUMAN | [view interactions] | High throughput | no | no |
RIR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAF5_HUMAN | [view interactions] | High throughput | no | yes |
TFAM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBL1R_HUMAN | [view interactions] | High throughput | no | yes |
PSA1_HUMAN | [view interactions] | High throughput | no | yes |
TDRD3_HUMAN | [view interactions] | High throughput | no | yes |
NAA15_HUMAN | [view interactions] | High throughput | no | yes |
TR150_HUMAN | [view interactions] | High throughput | no | yes |
CNPY2_HUMAN | [view interactions] | High throughput | no | yes |
TLK2_HUMAN | [view interactions] | High throughput | no | no |
ECHM_HUMAN | [view interactions] | High throughput | no | yes |
TRIO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANXA2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UBN2_HUMAN | [view interactions] | High throughput | no | yes |
COPB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBP10_HUMAN | [view interactions] | High throughput | no | yes |