SC24C_HUMAN
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed, PubMed, PubMed, PubMed). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed, PubMed, PubMed). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed). [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in SC24C_HUMAN |
---|---|---|---|---|
GO:0000166 | nucleotide binding | 31.4286 | 4 | no |
GO:0017076 | purine nucleotide binding | 31.4286 | 5 | no |
GO:0043168 | anion binding | 31.4286 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 28.5714 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 27.1429 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 21.4286 | 6 | no |
GO:0003723 | RNA binding | 21.4286 | 4 | no |
GO:0043169 | cation binding | 20.0000 | 4 | yes |
GO:0046872 | metal ion binding | 20.0000 | 5 | yes |
GO:0046914 | transition metal ion binding | 10.0000 | 6 | yes |
GO:0008270 | zinc ion binding | 8.5714 | 7 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in SC24C_HUMAN |
---|---|---|---|---|
GO:0008104 | protein localization | 55.7143 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 54.2857 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 52.8571 | 4 | no |
GO:0051128 | regulation of cellular component organization | 48.5714 | 4 | no |
GO:0071702 | organic substance transport | 47.1429 | 4 | yes |
GO:0006996 | organelle organization | 47.1429 | 4 | no |
GO:0048522 | positive regulation of cellular process | 47.1429 | 4 | no |
GO:0048523 | negative regulation of cellular process | 45.7143 | 4 | no |
GO:0071705 | nitrogen compound transport | 44.2857 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 42.8571 | 4 | no |
GO:0015031 | protein transport | 41.4286 | 4 | yes |
GO:0009893 | positive regulation of metabolic process | 41.4286 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 40.0000 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 40.0000 | 5 | no |
GO:0010646 | regulation of cell communication | 37.1429 | 4 | no |
GO:0009889 | regulation of biosynthetic process | 34.2857 | 4 | no |
GO:0022607 | cellular component assembly | 34.2857 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 34.2857 | 5 | no |
GO:0006886 | intracellular protein transport | 32.8571 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 32.8571 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 32.8571 | 5 | no |
GO:0009966 | regulation of signal transduction | 31.4286 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 31.4286 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 30.0000 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 28.5714 | 6 | no |
GO:1902531 | regulation of intracellular signal transduction | 28.5714 | 5 | no |
GO:0010468 | regulation of gene expression | 28.5714 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 28.5714 | 5 | no |
GO:0009894 | regulation of catabolic process | 27.1429 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 27.1429 | 5 | no |
GO:0033043 | regulation of organelle organization | 27.1429 | 5 | no |
GO:0036211 | protein modification process | 25.7143 | 4 | no |
GO:0043412 | macromolecule modification | 25.7143 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 25.7143 | 4 | no |
GO:0031399 | regulation of protein modification process | 24.2857 | 6 | no |
GO:0043933 | protein-containing complex organization | 24.2857 | 4 | no |
GO:0023056 | positive regulation of signaling | 24.2857 | 4 | no |
GO:0051252 | regulation of RNA metabolic process | 24.2857 | 5 | no |
GO:0051049 | regulation of transport | 24.2857 | 4 | no |
GO:0009891 | positive regulation of biosynthetic process | 22.8571 | 5 | no |
GO:0031328 | positive regulation of cellular biosynthetic process | 22.8571 | 6 | no |
GO:0009967 | positive regulation of signal transduction | 22.8571 | 5 | no |
GO:0010647 | positive regulation of cell communication | 22.8571 | 5 | no |
GO:0048584 | positive regulation of response to stimulus | 22.8571 | 4 | no |
GO:0098657 | import into cell | 21.4286 | 4 | no |
GO:0010557 | positive regulation of macromolecule biosynthetic process | 21.4286 | 6 | no |
GO:0009890 | negative regulation of biosynthetic process | 21.4286 | 5 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.4286 | 6 | no |
GO:0031327 | negative regulation of cellular biosynthetic process | 21.4286 | 6 | no |
GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 21.4286 | 5 | no |
GO:0060341 | regulation of cellular localization | 21.4286 | 4 | no |
GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | 15.7143 | 4 | yes |
GO:0035459 | vesicle cargo loading | 10.0000 | 4 | yes |
GO:0090110 | COPII-coated vesicle cargo loading | 8.5714 | 4 | yes |
GO:0001701 | in utero embryonic development | 4.2857 | 6 | yes |
GO:0009792 | embryo development ending in birth or egg hatching | 4.2857 | 4 | yes |
GO:0043009 | chordate embryonic development | 4.2857 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
SC23A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ERN1_HUMAN | [view interactions] | Low throughput | no | yes |
MIA2_HUMAN | [view interactions] | Low throughput | no | yes |
TGO1_HUMAN | [view interactions] | Low throughput | no | yes |
TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
CTRO_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRC1_HUMAN | [view interactions] | High throughput | no | yes |
CIC_HUMAN | [view interactions] | High throughput | no | yes |
RIGI_HUMAN | [view interactions] | High throughput | no | yes |
UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
PRRC1_HUMAN | [view interactions] | High throughput | no | yes |
SRA1_HUMAN | [view interactions] | High throughput | no | yes |
PIGR_HUMAN | [view interactions] | High throughput | no | no |
SCYL1_HUMAN | [view interactions] | High throughput | no | yes |
MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
YIF1A_HUMAN | [view interactions] | High throughput | no | yes |
ANM1_HUMAN | [view interactions] | High throughput | no | yes |
MYCN_HUMAN | [view interactions] | High throughput | no | no |
PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
VIGLN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRI67_HUMAN | [view interactions] | High throughput | no | no |
STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
ARF1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MA1A1_HUMAN | [view interactions] | High throughput | no | yes |
IF2B1_HUMAN | [view interactions] | High throughput | no | no |
CUL5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BAZ1A_HUMAN | [view interactions] | High throughput | no | no |
ARI2_HUMAN | [view interactions] | High throughput | no | no |
DAZP1_HUMAN | [view interactions] | High throughput | no | yes |
DCAF7_HUMAN | [view interactions] | High throughput | no | yes |
FUT8_HUMAN | [view interactions] | High throughput | no | yes |
UBC12_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
B4GT1_HUMAN | [view interactions] | High throughput | no | yes |
MPRI_HUMAN | [view interactions] | High throughput | no | yes |
NCOR1_HUMAN | [view interactions] | High throughput | no | yes |
RICTR_HUMAN | [view interactions] | High throughput | no | yes |
SC24A_HUMAN | [view interactions] | High throughput | no | no |
TPC11_HUMAN | [view interactions] | High throughput | no | no |
RAB5C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IGF1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EP300_HUMAN | [view interactions] | High throughput | no | yes |
SC24B_HUMAN | [view interactions] | High throughput | no | yes |
VPS51_HUMAN | [view interactions] | High throughput | no | yes |
RABX5_HUMAN | [view interactions] | High throughput | no | no |
MA1B1_HUMAN | [view interactions] | High throughput | no | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZNT5_HUMAN | [view interactions] | High throughput | no | yes |
S39A7_HUMAN | [view interactions] | High throughput | no | yes |
NPRL2_HUMAN | [view interactions] | High throughput | no | yes |
VPS45_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEPD5_HUMAN | [view interactions] | High throughput | no | yes |
ACATN_HUMAN | [view interactions] | High throughput | no | yes |
TPC13_HUMAN | [view interactions] | High throughput | no | yes |
EZH2_HUMAN | [view interactions] | High throughput | no | no |
NPRL3_HUMAN | [view interactions] | High throughput | no | yes |
PTEN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EED_HUMAN | [view interactions] | High throughput | no | yes |
VPS53_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UB2J1_HUMAN | [view interactions] | High throughput | no | yes |
CTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RAB1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPPC5_HUMAN | [view interactions] | High throughput | no | yes |
TPC12_HUMAN | [view interactions] | High throughput | no | yes |
RAB2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPC2A_HUMAN | [view interactions] | High throughput | no | yes |
SAR1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPC2L_HUMAN | [view interactions] | High throughput | no | yes |
TSC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
S39A9_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRYAA_HUMAN | [view interactions] | High throughput | no | no |
SC24D_HUMAN | [view interactions] | High throughput | no | yes |
DTNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RUXF_HUMAN | [view interactions] | High throughput | no | no |
NDUS1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CPLX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ICLN_HUMAN | [view interactions] | High throughput | no | yes |
COG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PSA5_HUMAN | [view interactions] | High throughput | no | yes |
COPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PICAL_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ANCHR_HUMAN | [view interactions] | High throughput | no | yes |
NOTC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MED15_HUMAN | [view interactions] | High throughput | no | yes |
SERPH_HUMAN | [view interactions] | High throughput | no | no |
PSMD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PPIL3_HUMAN | [view interactions] | High throughput | no | yes |
VATB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSDE1_HUMAN | [view interactions] | High throughput | no | yes |
OTU6B_HUMAN | [view interactions] | High throughput | no | yes |
SBNO1_HUMAN | [view interactions] | High throughput | no | yes |
DPYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PBDC1_HUMAN | [view interactions] | High throughput | no | no |
GMPR2_HUMAN | [view interactions] | High throughput | no | yes |
PARVA_HUMAN | [view interactions] | High throughput | no | yes |
SPT5H_HUMAN | [view interactions] | High throughput | no | yes |
XPO7_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ZYX_HUMAN | [view interactions] | High throughput | no | no |
SSRP1_HUMAN | [view interactions] | High throughput | no | yes |
CD2AP_HUMAN | [view interactions] | High throughput | no | no |
SH3K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYB5_HUMAN | [view interactions] | High throughput | no | no |
GGPPS_HUMAN | [view interactions] | High throughput | no | yes |
ERCC3_HUMAN | [view interactions] | High throughput | no | yes |
ILF3_HUMAN | [view interactions] | High throughput | no | yes |
PAK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FA50A_HUMAN | [view interactions] | High throughput | no | yes |
HERC4_HUMAN | [view interactions] | High throughput | no | no |
THOC4_HUMAN | [view interactions] | High throughput | no | no |
RENT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MGN2_HUMAN | [view interactions] | High throughput | no | yes |
UN45A_HUMAN | [view interactions] | High throughput | no | yes |
NT5D2_HUMAN | [view interactions] | High throughput | no | yes |
PDP1_HUMAN | [view interactions] | High throughput | no | yes |
ZN148_HUMAN | [view interactions] | High throughput | no | yes |
LEG9_HUMAN | [view interactions] | High throughput | no | yes |
DNJC7_HUMAN | [view interactions] | High throughput | no | yes |
DJB11_HUMAN | [view interactions] | High throughput | no | yes |
DNJC4_HUMAN | [view interactions] | High throughput | no | yes |
DNJ5G_HUMAN | [view interactions] | High throughput | no | no |
B3GA1_HUMAN | [view interactions] | High throughput | no | yes |
VP33A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
OPTN_HUMAN | [view interactions] | High throughput | no | yes |
PARP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SAR1B_HUMAN | [view interactions] | High throughput | no | yes |
CCNF_HUMAN | [view interactions] | High throughput | no | no |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TGON2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RFA1_HUMAN | [view interactions] | High throughput | no | yes |
RFA2_HUMAN | [view interactions] | High throughput | no | yes |
RFA3_HUMAN | [view interactions] | High throughput | no | yes |
P63_HUMAN | [view interactions] | High throughput | no | no |
MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
GBRL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
GBRAP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TMED2_HUMAN | [view interactions] | High throughput | no | yes |
MIS12_HUMAN | [view interactions] | High throughput | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDK1_HUMAN | [view interactions] | High throughput | no | no |
KAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OCRL_HUMAN | [view interactions] | High throughput | no | yes |
USO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SC16A_HUMAN | [view interactions] | High throughput | no | yes |
MAP7_HUMAN | [view interactions] | High throughput | no | yes |
ACK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CLH2_HUMAN | [view interactions] | High throughput | no | no |
STON2_HUMAN | [view interactions] | High throughput | no | yes |
PKP3_HUMAN | [view interactions] | High throughput | no | yes |
MB12A_HUMAN | [view interactions] | High throughput | no | yes |
EPN4_HUMAN | [view interactions] | High throughput | no | yes |
TROAP_HUMAN | [view interactions] | High throughput | no | yes |
FA83H_HUMAN | [view interactions] | High throughput | no | yes |
DAB2_HUMAN | [view interactions] | High throughput | no | yes |
SOAT1_HUMAN | [view interactions] | High throughput | no | no |
VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FA83B_HUMAN | [view interactions] | High throughput | no | no |
HIP1R_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KC1A_HUMAN | [view interactions] | High throughput | no | yes |
BMP2K_HUMAN | [view interactions] | High throughput | no | yes |
RBM14_HUMAN | [view interactions] | High throughput | no | yes |
GTSE1_HUMAN | [view interactions] | High throughput | no | no |
S35E1_HUMAN | [view interactions] | High throughput | no | yes |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
STX8_HUMAN | [view interactions] | High throughput | no | yes |
CRTC2_HUMAN | [view interactions] | High throughput | no | yes |
GAK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
FA83A_HUMAN | [view interactions] | High throughput | no | no |
SEC13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DEN1A_HUMAN | [view interactions] | High throughput | no | no |
CPVL_HUMAN | [view interactions] | High throughput | no | no |
EPS15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRTC3_HUMAN | [view interactions] | High throughput | no | no |
S23IP_HUMAN | [view interactions] | High throughput | no | yes |
S53A1_HUMAN | [view interactions] | High throughput | no | yes |
SC23B_HUMAN | [view interactions] | High throughput | no | yes |
CLH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CENPQ_HUMAN | [view interactions] | High throughput | no | yes |
PRD16_HUMAN | [view interactions] | High throughput | no | no |
LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
P53_HUMAN | [view interactions] | High throughput | no | no |
RAF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RMC1_HUMAN | [view interactions] | High throughput | no | no |
VCAM1_HUMAN | [view interactions] | High throughput | no | no |
FINC_HUMAN | [view interactions] | High throughput | no | yes |
H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
JUN_HUMAN | [view interactions] | High throughput | no | yes |
USE1_HUMAN | [view interactions] | High throughput | no | yes |
PKHA7_HUMAN | [view interactions] | High throughput | no | yes |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CFTR_HUMAN | [view interactions] | High throughput | no | no |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ADNP_HUMAN | [view interactions] | High throughput | no | yes |
CHD8_HUMAN | [view interactions] | High throughput | no | no |
FBX7_HUMAN | [view interactions] | High throughput | no | yes |
WIPF1_HUMAN | [view interactions] | High throughput | no | no |
MOS_HUMAN | [view interactions] | High throughput | no | no |
CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CNTRL_HUMAN | [view interactions] | High throughput | no | yes |
STIL_HUMAN | [view interactions] | High throughput | no | no |
OSTP_HUMAN | [view interactions] | High throughput | no | yes |
SIR7_HUMAN | [view interactions] | High throughput | no | yes |
ITA4_HUMAN | [view interactions] | High throughput | no | no |
WWOX_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MOV10_HUMAN | [view interactions] | High throughput | no | no |
NXF1_HUMAN | [view interactions] | High throughput | no | yes |
OBSL1_HUMAN | [view interactions] | High throughput | no | yes |
NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
EWS_HUMAN | [view interactions] | High throughput | no | yes |
CENPE_HUMAN | [view interactions] | High throughput | no | no |
G3BP1_HUMAN | [view interactions] | High throughput | no | yes |
BRCA1_HUMAN | [view interactions] | High throughput | no | yes |
SC31A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LNP_HUMAN | [view interactions] | High throughput | no | yes |
CTNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U5S1_HUMAN | [view interactions] | High throughput | no | yes |
AAR2_HUMAN | [view interactions] | High throughput | no | no |
PIHD1_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
H4_HUMAN | [view interactions] | High throughput | no | yes |
PKHA2_HUMAN | [view interactions] | High throughput | no | no |
NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
WWP2_HUMAN | [view interactions] | High throughput | no | no |