USP9X_HUMAN
Evidence for PS localization
Functions
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes Lys-48-, Lys-29- and Lys-33-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed, PubMed, PubMed, PubMed). Regulates cellular clock function by enhancing the protein stability and transcriptional activity of the core circadian protein ARNTL/BMAL1 via its deubiquitinating activity (PubMed). [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 1693 | Leu | Trp | Intellectualdevelopmentaldisorder,X-linked99,syndromic,female-restricted(MRXS99F) | - |
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in USP9X_HUMAN |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | 30.4348 | 4 | no |
| GO:0017076 | purine nucleotide binding | 30.4348 | 5 | no |
| GO:0032555 | purine ribonucleotide binding | 30.4348 | 4 | no |
| GO:0043168 | anion binding | 30.4348 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 29.5652 | 4 | no |
| GO:0043169 | cation binding | 25.2174 | 4 | no |
| GO:0046872 | metal ion binding | 25.2174 | 5 | no |
| GO:0030554 | adenyl nucleotide binding | 24.3478 | 6 | no |
| GO:0032559 | adenyl ribonucleotide binding | 24.3478 | 5 | no |
| GO:0005524 | ATP binding | 23.4783 | 5 | no |
| GO:0003723 | RNA binding | 23.4783 | 4 | no |
| GO:0019900 | kinase binding | 22.6087 | 4 | no |
| GO:0019901 | protein kinase binding | 20.8696 | 5 | no |
| GO:0004175 | endopeptidase activity | 1.7391 | 4 | yes |
| GO:0004197 | cysteine-type endopeptidase activity | 1.7391 | 5 | yes |
| GO:0004843 | cysteine-type deubiquitinase activity | 1.7391 | 5 | yes |
| GO:0008234 | cysteine-type peptidase activity | 1.7391 | 4 | yes |
| GO:0019783 | ubiquitin-like protein peptidase activity | 1.7391 | 4 | yes |
| GO:0061578 | K63-linked deubiquitinase activity | 1.7391 | 6 | yes |
| GO:0070410 | co-SMAD binding | 1.7391 | 4 | yes |
| GO:0101005 | deubiquitinase activity | 1.7391 | 5 | yes |
| GO:0180017 | K11-linked deubiquitinase activity | 1.7391 | 6 | yes |
| GO:1990380 | K48-linked deubiquitinase activity | 1.7391 | 6 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in USP9X_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 61.7391 | 4 | yes |
| GO:0060255 | regulation of macromolecule metabolic process | 58.2609 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 57.3913 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 53.9130 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 52.1739 | 4 | yes |
| GO:0010646 | regulation of cell communication | 50.4348 | 4 | yes |
| GO:0009889 | regulation of biosynthetic process | 49.5652 | 4 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 48.6957 | 5 | yes |
| GO:0009893 | positive regulation of metabolic process | 47.8261 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 46.9565 | 5 | yes |
| GO:0051128 | regulation of cellular component organization | 45.2174 | 4 | no |
| GO:0010468 | regulation of gene expression | 43.4783 | 6 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 43.4783 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 41.7391 | 4 | yes |
| GO:0031325 | positive regulation of cellular metabolic process | 38.2609 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 37.3913 | 5 | yes |
| GO:0051246 | regulation of protein metabolic process | 35.6522 | 5 | yes |
| GO:0006996 | organelle organization | 35.6522 | 4 | no |
| GO:0048584 | positive regulation of response to stimulus | 33.9130 | 4 | yes |
| GO:0022607 | cellular component assembly | 33.0435 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 32.1739 | 5 | yes |
| GO:1902531 | regulation of intracellular signal transduction | 32.1739 | 5 | yes |
| GO:0008104 | protein localization | 32.1739 | 4 | yes |
| GO:0010647 | positive regulation of cell communication | 32.1739 | 5 | yes |
| GO:0009892 | negative regulation of metabolic process | 31.3043 | 4 | yes |
| GO:0023056 | positive regulation of signaling | 31.3043 | 4 | yes |
| GO:0036211 | protein modification process | 31.3043 | 4 | yes |
| GO:0043412 | macromolecule modification | 31.3043 | 4 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 30.4348 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 29.5652 | 6 | no |
| GO:2001141 | regulation of RNA biosynthetic process | 28.6957 | 6 | yes |
| GO:0051049 | regulation of transport | 28.6957 | 4 | no |
| GO:0006355 | regulation of DNA-templated transcription | 28.6957 | 7 | yes |
| GO:0009967 | positive regulation of signal transduction | 28.6957 | 5 | yes |
| GO:0010605 | negative regulation of macromolecule metabolic process | 28.6957 | 5 | yes |
| GO:0031324 | negative regulation of cellular metabolic process | 28.6957 | 5 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 27.8261 | 6 | no |
| GO:0051130 | positive regulation of cellular component organization | 27.8261 | 5 | no |
| GO:0009894 | regulation of catabolic process | 27.8261 | 4 | yes |
| GO:0042981 | regulation of apoptotic process | 26.0870 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 26.0870 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 26.0870 | 6 | no |
| GO:0010648 | negative regulation of cell communication | 26.0870 | 5 | no |
| GO:0023057 | negative regulation of signaling | 26.0870 | 4 | no |
| GO:0044087 | regulation of cellular component biogenesis | 26.0870 | 4 | no |
| GO:0009890 | negative regulation of biosynthetic process | 25.2174 | 5 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 24.3478 | 5 | yes |
| GO:0031399 | regulation of protein modification process | 24.3478 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 24.3478 | 4 | no |
| GO:0060341 | regulation of cellular localization | 24.3478 | 4 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 24.3478 | 6 | yes |
| GO:0009968 | negative regulation of signal transduction | 23.4783 | 5 | no |
| GO:0033043 | regulation of organelle organization | 23.4783 | 5 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 23.4783 | 6 | yes |
| GO:0030030 | cell projection organization | 22.6087 | 4 | no |
| GO:0006796 | phosphate-containing compound metabolic process | 21.7391 | 4 | no |
| GO:0042127 | regulation of cell population proliferation | 21.7391 | 4 | no |
| GO:0032880 | regulation of protein localization | 21.7391 | 5 | no |
| GO:1902533 | positive regulation of intracellular signal transduction | 20.8696 | 6 | yes |
| GO:0045595 | regulation of cell differentiation | 20.8696 | 4 | no |
| GO:0071310 | cellular response to organic substance | 20.8696 | 4 | no |
| GO:0006357 | regulation of transcription by RNA polymerase II | 17.3913 | 8 | yes |
| GO:0051248 | negative regulation of protein metabolic process | 16.5217 | 6 | yes |
| GO:0030162 | regulation of proteolysis | 16.5217 | 6 | yes |
| GO:0043687 | post-translational protein modification | 16.5217 | 5 | yes |
| GO:0070647 | protein modification by small protein conjugation or removal | 15.6522 | 6 | yes |
| GO:0032446 | protein modification by small protein conjugation | 15.6522 | 7 | yes |
| GO:0042176 | regulation of protein catabolic process | 14.7826 | 5 | yes |
| GO:0045934 | negative regulation of nucleobase-containing compound metabolic process | 13.0435 | 5 | yes |
| GO:0051253 | negative regulation of RNA metabolic process | 13.0435 | 6 | yes |
| GO:1903050 | regulation of proteolysis involved in protein catabolic process | 13.0435 | 7 | yes |
| GO:0016567 | protein ubiquitination | 13.0435 | 8 | yes |
| GO:0097435 | supramolecular fiber organization | 12.1739 | 4 | yes |
| GO:1902679 | negative regulation of RNA biosynthetic process | 12.1739 | 7 | yes |
| GO:2000058 | regulation of ubiquitin-dependent protein catabolic process | 12.1739 | 5 | yes |
| GO:0045892 | negative regulation of DNA-templated transcription | 12.1739 | 8 | yes |
| GO:0007167 | enzyme-linked receptor protein signaling pathway | 11.3043 | 4 | yes |
| GO:0050821 | protein stabilization | 10.4348 | 4 | yes |
| GO:0061136 | regulation of proteasomal protein catabolic process | 10.4348 | 6 | yes |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | 9.5652 | 6 | yes |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 8.6957 | 9 | yes |
| GO:0001764 | neuron migration | 8.6957 | 4 | yes |
| GO:0009895 | negative regulation of catabolic process | 8.6957 | 5 | yes |
| GO:0043393 | regulation of protein binding | 8.6957 | 4 | yes |
| GO:0051052 | regulation of DNA metabolic process | 7.8261 | 5 | yes |
| GO:1990138 | neuron projection extension | 7.8261 | 4 | yes |
| GO:0051054 | positive regulation of DNA metabolic process | 6.9565 | 6 | yes |
| GO:0051099 | positive regulation of binding | 6.9565 | 4 | yes |
| GO:0045861 | negative regulation of proteolysis | 6.0870 | 7 | yes |
| GO:1990000 | amyloid fibril formation | 5.2174 | 4 | yes |
| GO:0032006 | regulation of TOR signaling | 5.2174 | 6 | yes |
| GO:0032092 | positive regulation of protein binding | 5.2174 | 5 | yes |
| GO:0042177 | negative regulation of protein catabolic process | 5.2174 | 6 | yes |
| GO:0048675 | axon extension | 3.4783 | 5 | yes |
| GO:0070646 | protein modification by small protein removal | 2.6087 | 7 | yes |
| GO:1901799 | negative regulation of proteasomal protein catabolic process | 2.6087 | 7 | yes |
| GO:1903051 | negative regulation of proteolysis involved in protein catabolic process | 2.6087 | 8 | yes |
| GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | 2.6087 | 6 | yes |
| GO:0001881 | receptor recycling | 2.6087 | 5 | yes |
| GO:0032008 | positive regulation of TOR signaling | 2.6087 | 7 | yes |
| GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | 2.6087 | 7 | yes |
| GO:0043112 | receptor metabolic process | 2.6087 | 4 | yes |
| GO:0070536 | protein K63-linked deubiquitination | 1.7391 | 9 | yes |
| GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process | 1.7391 | 9 | yes |
| GO:0141091 | transforming growth factor beta receptor superfamily signaling pathway | 1.7391 | 6 | yes |
| GO:1901535 | regulation of DNA demethylation | 1.7391 | 6 | yes |
| GO:1901537 | positive regulation of DNA demethylation | 1.7391 | 7 | yes |
| GO:1903939 | regulation of TORC2 signaling | 1.7391 | 7 | yes |
| GO:1904515 | positive regulation of TORC2 signaling | 1.7391 | 8 | yes |
| GO:0007178 | cell surface receptor protein serine/threonine kinase signaling pathway | 1.7391 | 5 | yes |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.7391 | 7 | yes |
| GO:0007292 | female gamete generation | 1.7391 | 4 | yes |
| GO:0016562 | protein import into peroxisome matrix, receptor recycling | 1.7391 | 6 | yes |
| GO:0016579 | protein deubiquitination | 1.7391 | 8 | yes |
| GO:0030509 | BMP signaling pathway | 1.7391 | 7 | yes |
| GO:0035520 | monoubiquitinated protein deubiquitination | 1.7391 | 9 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| DCX_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CTNB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AFAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ITCH_HUMAN | [view interactions] | Low throughput | no | yes |
| BIRC5_HUMAN | [view interactions] | Low throughput | no | no |
| M3K5_HUMAN | [view interactions] | Low throughput | no | yes |
| PSD4_HUMAN | [view interactions] | Low throughput | no | yes |
| GPSM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SMAD1_HUMAN | [view interactions] | Low throughput | no | yes |
| RICTR_HUMAN | [view interactions] | Low throughput | no | yes |
| MARH7_HUMAN | [view interactions] | Low throughput | no | yes |
| SMUF1_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL10_HUMAN | [view interactions] | Low throughput | no | yes |
| MALT1_HUMAN | [view interactions] | Low throughput | no | no |
| ERG_HUMAN | [view interactions] | Low throughput | no | yes |
| AMOL2_HUMAN | [view interactions] | Low throughput | no | no |
| YAP1_HUMAN | [view interactions] | Low throughput | no | yes |
| UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NANOG_HUMAN | [view interactions] | Low throughput | no | no |
| SMN_HUMAN | [view interactions] | Low throughput | no | yes |
| TDRD3_HUMAN | [view interactions] | Low throughput | no | yes |
| AMOT_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| VHL_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LAT_HUMAN | [view interactions] | Low throughput | no | no |
| KPCB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| USP9X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LATS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IQCB1_HUMAN | [view interactions] | Low throughput | no | no |
| ZN598_HUMAN | [view interactions] | Low throughput | no | no |
| EGLN3_HUMAN | [view interactions] | Low throughput | no | no |
| PCM1_HUMAN | [view interactions] | Low throughput | no | yes |
| CEP55_HUMAN | [view interactions] | Low throughput | no | yes |
| BAG3_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| TTK_HUMAN | [view interactions] | Low throughput | no | yes |
| FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
| ZBT38_HUMAN | [view interactions] | Low throughput | no | no |
| UBP7_HUMAN | [view interactions] | Low throughput | no | yes |
| PD1L1_HUMAN | [view interactions] | Low throughput | no | no |
| IRS1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| IRS2_HUMAN | [view interactions] | Low throughput | no | yes |
| IGF1R_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CE290_HUMAN | [view interactions] | Low throughput | no | no |
| ATX10_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| CE170_HUMAN | [view interactions] | Low throughput | no | yes |
| RN115_HUMAN | [view interactions] | Low throughput | no | yes |
| AL1A3_HUMAN | [view interactions] | Low throughput | no | yes |
| PBX1_HUMAN | [view interactions] | Low throughput | no | yes |
| BCL9_HUMAN | [view interactions] | Low throughput | no | yes |
| SFI1_HUMAN | [view interactions] | Low throughput | no | no |
| STIL_HUMAN | [view interactions] | Low throughput | no | no |
| PTGES_HUMAN | [view interactions] | Low throughput | no | no |
| DVL2_HUMAN | [view interactions] | Low throughput | no | yes |
| PTEN_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BRCA1_HUMAN | [view interactions] | Low throughput | no | yes |
| KDM1A_HUMAN | [view interactions] | Low throughput | no | yes |
| HD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MARK4_HUMAN | [view interactions] | Low throughput | no | yes |
| SMAD4_HUMAN | [view interactions] | Low throughput | no | yes |
| SMAD2_HUMAN | [view interactions] | Low throughput | no | yes |
| ANK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| SMAD3_HUMAN | [view interactions] | Low throughput | no | yes |
| NF2L2_HUMAN | [view interactions] | Low throughput | no | yes |
| LATS2_HUMAN | [view interactions] | Low throughput | no | yes |
| KLF4_HUMAN | [view interactions] | Low throughput | no | no |
| CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| MCL1_HUMAN | [view interactions] | Low throughput | no | yes |
| HIF1A_HUMAN | [view interactions] | Low throughput | no | no |
| SOX2_HUMAN | [view interactions] | Low throughput | no | yes |
| DDX3X_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| HMGA1_HUMAN | [view interactions] | Low throughput | no | yes |
| PEF1_HUMAN | [view interactions] | Low throughput | no | no |
| PSD1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| MSRE_HUMAN | [view interactions] | Low throughput | no | no |
| SNAI1_HUMAN | [view interactions] | Low throughput | no | yes |
| RNF6_HUMAN | [view interactions] | Low throughput | no | no |
| NUAK1_HUMAN | [view interactions] | Low throughput | no | no |
| ALKB5_HUMAN | [view interactions] | Low throughput | no | yes |
| FLI1_HUMAN | [view interactions] | Low throughput | no | no |
| NRP1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| NLRP3_HUMAN | [view interactions] | Low throughput | no | no |
| HUWE1_HUMAN | [view interactions] | Low throughput | no | yes |
| SGTA_HUMAN | [view interactions] | Low throughput | no | yes |
| PEX5_HUMAN | [view interactions] | Low throughput | no | yes |
| CADH1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
| LTK_HUMAN | [view interactions] | High throughput | no | no |
| UFC1_HUMAN | [view interactions] | High throughput | no | yes |
| MERTK_HUMAN | [view interactions] | High throughput | no | yes |
| UBE4B_HUMAN | [view interactions] | High throughput | no | yes |
| TIE2_HUMAN | [view interactions] | High throughput | no | no |
| SC24C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HOOK2_HUMAN | [view interactions] | High throughput | no | yes |
| TTL12_HUMAN | [view interactions] | High throughput | no | yes |
| PSB4_HUMAN | [view interactions] | High throughput | no | yes |
| PSA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2D2_HUMAN | [view interactions] | High throughput | no | yes |
| UBL7_HUMAN | [view interactions] | High throughput | no | yes |
| UBP34_HUMAN | [view interactions] | High throughput | no | yes |
| TERF1_HUMAN | [view interactions] | High throughput | no | no |
| U520_HUMAN | [view interactions] | High throughput | no | yes |
| TERF2_HUMAN | [view interactions] | High throughput | no | yes |
| IGBP1_HUMAN | [view interactions] | High throughput | no | yes |
| ANCHR_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC5_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN7_HUMAN | [view interactions] | High throughput | no | yes |
| PSB8_HUMAN | [view interactions] | High throughput | no | yes |
| PRAF3_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NUBP2_HUMAN | [view interactions] | High throughput | no | yes |
| SIR7_HUMAN | [view interactions] | High throughput | no | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NFX1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTOR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| RPTOR_HUMAN | [view interactions] | High throughput | no | yes |
| OTUB1_HUMAN | [view interactions] | High throughput | no | yes |
| IMA4_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD4_HUMAN | [view interactions] | High throughput | no | no |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| MAGD1_HUMAN | [view interactions] | High throughput | no | no |
| H2AY_HUMAN | [view interactions] | High throughput | no | yes |
| PJA1_HUMAN | [view interactions] | High throughput | no | yes |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| EF1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| GNL1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECT2_HUMAN | [view interactions] | High throughput | no | no |
| MAP1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ELP1_HUMAN | [view interactions] | High throughput | no | yes |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| IMA5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSN2_HUMAN | [view interactions] | High throughput | no | yes |
| RS3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EGFR_HUMAN | [view interactions] | High throughput | no | no |
| TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
| MIB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| BPTF_HUMAN | [view interactions] | High throughput | no | yes |
| ASB15_HUMAN | [view interactions] | High throughput | no | no |
| SRSF6_HUMAN | [view interactions] | High throughput | no | yes |
| TSR1_HUMAN | [view interactions] | High throughput | no | no |
| AURKA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ARI4B_HUMAN | [view interactions] | High throughput | no | yes |
| CCDC8_HUMAN | [view interactions] | High throughput | no | yes |
| EAPP_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| CSN6_HUMAN | [view interactions] | High throughput | no | yes |
| PEG10_HUMAN | [view interactions] | High throughput | no | no |
| KI21A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6B2_HUMAN | [view interactions] | High throughput | no | yes |
| SRRM1_HUMAN | [view interactions] | High throughput | no | yes |
| UNK_HUMAN | [view interactions] | High throughput | no | yes |
| CSN5_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| TNPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRIC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| PRIC2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| H2A1J_HUMAN | [view interactions] | High throughput | no | yes |
| CRY1_HUMAN | [view interactions] | High throughput | no | yes |
| CSN4_HUMAN | [view interactions] | High throughput | no | yes |
| CRY2_HUMAN | [view interactions] | High throughput | no | yes |
| CRNL1_HUMAN | [view interactions] | High throughput | no | no |
| OTUD4_HUMAN | [view interactions] | High throughput | no | yes |
| ADNP_HUMAN | [view interactions] | High throughput | no | yes |
| ALKB3_HUMAN | [view interactions] | High throughput | no | yes |
| PHAX_HUMAN | [view interactions] | High throughput | no | yes |
| MCM2_HUMAN | [view interactions] | High throughput | no | no |
| G3BP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARI1_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| TF3C3_HUMAN | [view interactions] | High throughput | no | no |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| CAF1A_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PCGF1_HUMAN | [view interactions] | High throughput | no | yes |
| ADAS_HUMAN | [view interactions] | High throughput | no | yes |
| DPPA4_HUMAN | [view interactions] | High throughput | no | no |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AT2A1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PO5F1_HUMAN | [view interactions] | High throughput | no | yes |
| EMD_HUMAN | [view interactions] | High throughput | no | yes |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| GEMI2_HUMAN | [view interactions] | High throughput | no | yes |
| LMNB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DDX20_HUMAN | [view interactions] | High throughput | no | no |
| MK67I_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI4_HUMAN | [view interactions] | High throughput | no | yes |
| PEX3_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI5_HUMAN | [view interactions] | High throughput | no | yes |
| SC61B_HUMAN | [view interactions] | High throughput | no | yes |
| GEMI8_HUMAN | [view interactions] | High throughput | no | yes |
| AMPN_HUMAN | [view interactions] | High throughput | no | no |
| RSMB_HUMAN | [view interactions] | High throughput | no | yes |
| GEPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PPM1B_HUMAN | [view interactions] | High throughput | no | yes |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| WWP2_HUMAN | [view interactions] | High throughput | no | no |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SYNPO_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN746_HUMAN | [view interactions] | High throughput | no | no |
| PTN14_HUMAN | [view interactions] | High throughput | no | yes |
| ZNHI2_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| TES_HUMAN | [view interactions] | High throughput | no | yes |
| KIBRA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AMOL1_HUMAN | [view interactions] | High throughput | no | no |
| SAV1_HUMAN | [view interactions] | High throughput | no | yes |
| LNX1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| NFKB1_HUMAN | [view interactions] | High throughput | no | yes |
| MINY4_HUMAN | [view interactions] | High throughput | no | yes |
| SPDLY_HUMAN | [view interactions] | High throughput | no | yes |
| ARRD3_HUMAN | [view interactions] | High throughput | no | no |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| HEXI1_HUMAN | [view interactions] | High throughput | no | yes |
| WWOX_HUMAN | [view interactions] | High throughput | no | yes |
| RECQ4_HUMAN | [view interactions] | High throughput | no | yes |
| AL1L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TXNIP_HUMAN | [view interactions] | High throughput | no | no |
| GLP1R_HUMAN | [view interactions] | High throughput | no | no |
| KDM6B_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| AMRA1_HUMAN | [view interactions] | High throughput | no | yes |
| IF4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RC3H1_HUMAN | [view interactions] | High throughput | no | yes |
| TCTP_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RU17_HUMAN | [view interactions] | High throughput | no | yes |
| MATR3_HUMAN | [view interactions] | High throughput | no | yes |
| STAU1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| PGRC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WWP1_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| ANR55_HUMAN | [view interactions] | High throughput | no | yes |
| CHM4B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| MAFB_HUMAN | [view interactions] | High throughput | no | yes |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CFAD_HUMAN | [view interactions] | High throughput | no | no |
| FNDC5_HUMAN | [view interactions] | High throughput | no | no |
| LEG9_HUMAN | [view interactions] | High throughput | no | yes |
| TM192_HUMAN | [view interactions] | High throughput | no | yes |
| M3K7_HUMAN | [view interactions] | High throughput | no | yes |
| KDF1_HUMAN | [view interactions] | High throughput | no | yes |
| SALL4_HUMAN | [view interactions] | High throughput | no | no |
| DDRGK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| FZR1_HUMAN | [view interactions] | High throughput | no | no |
| HDAC6_HUMAN | [view interactions] | High throughput | no | yes |
| CPNE2_HUMAN | [view interactions] | High throughput | no | yes |
| RASFA_HUMAN | [view interactions] | High throughput | no | no |
| PLCD4_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| F168A_HUMAN | [view interactions] | High throughput | no | yes |
| BIRC2_HUMAN | [view interactions] | High throughput | no | yes |
| DGKG_HUMAN | [view interactions] | High throughput | no | no |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| IRS4_HUMAN | [view interactions] | High throughput | no | no |
| WDR54_HUMAN | [view interactions] | High throughput | no | no |
| NEDD1_HUMAN | [view interactions] | High throughput | no | yes |
| ABT1_HUMAN | [view interactions] | High throughput | no | no |
| MOES_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MZF1_HUMAN | [view interactions] | High throughput | no | yes |
| OXND1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN764_HUMAN | [view interactions] | High throughput | no | no |
| ATP7A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKBL1_HUMAN | [view interactions] | High throughput | no | no |
| SODC_HUMAN | [view interactions] | High throughput | no | yes |
| P5CR3_HUMAN | [view interactions] | High throughput | no | no |
| ECM29_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| KSR2_HUMAN | [view interactions] | High throughput | no | yes |
| ZN363_HUMAN | [view interactions] | High throughput | no | yes |
| ZN408_HUMAN | [view interactions] | High throughput | no | no |
| ZN263_HUMAN | [view interactions] | High throughput | no | yes |
| KDM4C_HUMAN | [view interactions] | High throughput | no | no |
| SUV3_HUMAN | [view interactions] | High throughput | no | yes |
| HEXI2_HUMAN | [view interactions] | High throughput | no | yes |
| HECD1_HUMAN | [view interactions] | High throughput | no | yes |
| SUV91_HUMAN | [view interactions] | High throughput | no | no |
| SIR6_HUMAN | [view interactions] | High throughput | no | yes |
| NUDC1_HUMAN | [view interactions] | High throughput | no | no |
| CDC42_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ECH1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOG_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| MK06_HUMAN | [view interactions] | High throughput | no | yes |
| RHOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| RHOJ_HUMAN | [view interactions] | High throughput | no | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| RAC2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MP2K3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SHC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOD_HUMAN | [view interactions] | High throughput | no | no |
| GRB10_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOF_HUMAN | [view interactions] | High throughput | no | no |
| KS6A1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOU_HUMAN | [view interactions] | High throughput | no | no |
| KPCD1_HUMAN | [view interactions] | High throughput | no | yes |
| RHOV_HUMAN | [view interactions] | High throughput | no | no |
| RIN3_HUMAN | [view interactions] | High throughput | no | yes |
| RHBT1_HUMAN | [view interactions] | High throughput | no | yes |
| RHBT2_HUMAN | [view interactions] | High throughput | no | no |
| CNR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RHOH_HUMAN | [view interactions] | High throughput | no | yes |
| ZN516_HUMAN | [view interactions] | High throughput | no | yes |
| RND2_HUMAN | [view interactions] | High throughput | no | no |
| PTPC1_HUMAN | [view interactions] | High throughput | no | yes |
| RAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PTN21_HUMAN | [view interactions] | High throughput | no | yes |
| HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GATA3_HUMAN | [view interactions] | High throughput | no | no |
| MTMR1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM45_HUMAN | [view interactions] | High throughput | no | yes |
| P85B_HUMAN | [view interactions] | High throughput | no | yes |
| RMC1_HUMAN | [view interactions] | High throughput | no | no |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| TTC7A_HUMAN | [view interactions] | High throughput | no | yes |
| TCF25_HUMAN | [view interactions] | High throughput | no | yes |
| ZKSC3_HUMAN | [view interactions] | High throughput | no | yes |
| ZN446_HUMAN | [view interactions] | High throughput | no | yes |
| ANM1_HUMAN | [view interactions] | High throughput | no | yes |
| ZN304_HUMAN | [view interactions] | High throughput | no | yes |
| ZN416_HUMAN | [view interactions] | High throughput | no | no |
| AAPK2_HUMAN | [view interactions] | High throughput | no | yes |
| HNRPM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KLH12_HUMAN | [view interactions] | High throughput | no | no |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MEX3C_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HG2A_HUMAN | [view interactions] | High throughput | no | yes |
| DDX60_HUMAN | [view interactions] | High throughput | no | no |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| GCH1_HUMAN | [view interactions] | High throughput | no | no |
| BAP1_HUMAN | [view interactions] | High throughput | no | yes |
| P2RY6_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DISC1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PAK4_HUMAN | [view interactions] | High throughput | no | yes |
| GBRA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PARPT_HUMAN | [view interactions] | High throughput | no | no |
| CLK3_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| IRAK1_HUMAN | [view interactions] | High throughput | no | yes |
| RUFY1_HUMAN | [view interactions] | High throughput | no | yes |
| KS6A3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| JAK3_HUMAN | [view interactions] | High throughput | no | no |
| TRI33_HUMAN | [view interactions] | High throughput | no | yes |
| M3K10_HUMAN | [view interactions] | High throughput | no | yes |
| TNK1_HUMAN | [view interactions] | High throughput | no | yes |
| RPN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KS6A2_HUMAN | [view interactions] | High throughput | no | yes |
| STIP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K21_HUMAN | [view interactions] | High throughput | no | yes |
| MYO10_HUMAN | [view interactions] | High throughput | no | no |
| PKN3_HUMAN | [view interactions] | High throughput | no | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOB3C_HUMAN | [view interactions] | High throughput | no | no |
| CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PP14B_HUMAN | [view interactions] | High throughput | no | yes |
| BRSK1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MYO3B_HUMAN | [view interactions] | High throughput | no | yes |
| NUAK2_HUMAN | [view interactions] | High throughput | no | yes |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| PAK6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF6_HUMAN | [view interactions] | High throughput | no | no |
| MAST1_HUMAN | [view interactions] | High throughput | no | yes |
| NEK6_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2H_HUMAN | [view interactions] | High throughput | no | yes |
| CASP4_HUMAN | [view interactions] | High throughput | no | yes |
| FITM2_HUMAN | [view interactions] | High throughput | no | no |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| ATG12_HUMAN | [view interactions] | High throughput | no | yes |
| T22D1_HUMAN | [view interactions] | High throughput | no | no |
| FAS_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AXIN1_HUMAN | [view interactions] | High throughput | no | yes |
| LDLR_HUMAN | [view interactions] | High throughput | no | yes |
| RIT1_HUMAN | [view interactions] | High throughput | no | yes |
| PP1A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBP24_HUMAN | [view interactions] | High throughput | no | yes |
| FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ITB2_HUMAN | [view interactions] | High throughput | no | no |
| TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SUMO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DLGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| RL40_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| M3K1_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2B_HUMAN | [view interactions] | High throughput | no | no |
| NFKB2_HUMAN | [view interactions] | High throughput | no | yes |
| UB2V2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RELB_HUMAN | [view interactions] | High throughput | no | yes |
| UBXN1_HUMAN | [view interactions] | High throughput | no | no |
| CAND1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UB2L3_HUMAN | [view interactions] | High throughput | no | yes |
| KATIP_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRD2_HUMAN | [view interactions] | High throughput | no | yes |
| TIAM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UCHL3_HUMAN | [view interactions] | High throughput | no | yes |
| RSPH1_HUMAN | [view interactions] | High throughput | no | no |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBQL2_HUMAN | [view interactions] | High throughput | no | yes |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| UBE2C_HUMAN | [view interactions] | High throughput | no | yes |
| UFO_HUMAN | [view interactions] | High throughput | no | no |
| SC23A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ERBB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SRXN1_HUMAN | [view interactions] | High throughput | no | no |
| FGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| ZYX_HUMAN | [view interactions] | High throughput | no | no |
| VGFR1_HUMAN | [view interactions] | High throughput | no | no |
| VATF_HUMAN | [view interactions] | High throughput | no | yes |
| FLT3_HUMAN | [view interactions] | High throughput | no | no |
| UBQL1_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR3_HUMAN | [view interactions] | High throughput | no | yes |
| UFM1_HUMAN | [view interactions] | High throughput | no | yes |
| LMTK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SAHH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |