KI21A_HUMAN
Evidence for PS localization
Functions
Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in KI21A_HUMAN |
|---|---|---|---|---|
| GO:0043168 | anion binding | 43.2432 | 4 | yes |
| GO:0000166 | nucleotide binding | 37.8378 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 37.8378 | 5 | yes |
| GO:0030554 | adenyl nucleotide binding | 37.8378 | 6 | yes |
| GO:0032555 | purine ribonucleotide binding | 37.8378 | 4 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 37.8378 | 5 | yes |
| GO:0005524 | ATP binding | 35.1351 | 5 | yes |
| GO:0016462 | pyrophosphatase activity | 35.1351 | 5 | yes |
| GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 35.1351 | 4 | yes |
| GO:0016887 | ATP hydrolysis activity | 35.1351 | 7 | yes |
| GO:0017111 | ribonucleoside triphosphate phosphatase activity | 35.1351 | 6 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 35.1351 | 4 | yes |
| GO:0003723 | RNA binding | 29.7297 | 4 | no |
| GO:0019900 | kinase binding | 24.3243 | 4 | no |
| GO:0019901 | protein kinase binding | 24.3243 | 5 | no |
| GO:0043169 | cation binding | 24.3243 | 4 | no |
| GO:0046872 | metal ion binding | 24.3243 | 5 | no |
| GO:0015631 | tubulin binding | 18.9189 | 4 | yes |
| GO:0008017 | microtubule binding | 10.8108 | 5 | yes |
| GO:0071532 | ankyrin repeat binding | 5.4054 | 4 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in KI21A_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 70.2703 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 67.5676 | 4 | no |
| GO:0080090 | regulation of primary metabolic process | 64.8649 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 62.1622 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 56.7568 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 54.0541 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 54.0541 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 54.0541 | 5 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 51.3514 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 51.3514 | 5 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 48.6486 | 5 | no |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 45.9459 | 5 | no |
| GO:0033043 | regulation of organelle organization | 45.9459 | 5 | no |
| GO:0048523 | negative regulation of cellular process | 43.2432 | 4 | no |
| GO:0051130 | positive regulation of cellular component organization | 40.5405 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 40.5405 | 4 | no |
| GO:0009891 | positive regulation of biosynthetic process | 40.5405 | 5 | no |
| GO:0031328 | positive regulation of cellular biosynthetic process | 40.5405 | 6 | no |
| GO:0010646 | regulation of cell communication | 37.8378 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 37.8378 | 5 | no |
| GO:0051246 | regulation of protein metabolic process | 37.8378 | 5 | no |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 37.8378 | 6 | no |
| GO:0010638 | positive regulation of organelle organization | 37.8378 | 6 | no |
| GO:0060341 | regulation of cellular localization | 35.1351 | 4 | no |
| GO:1903829 | positive regulation of protein localization | 35.1351 | 5 | no |
| GO:0032880 | regulation of protein localization | 35.1351 | 5 | no |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 35.1351 | 5 | no |
| GO:0009966 | regulation of signal transduction | 32.4324 | 4 | no |
| GO:0010605 | negative regulation of macromolecule metabolic process | 32.4324 | 5 | no |
| GO:0022607 | cellular component assembly | 32.4324 | 4 | no |
| GO:0050821 | protein stabilization | 32.4324 | 4 | no |
| GO:0031399 | regulation of protein modification process | 29.7297 | 6 | no |
| GO:0043085 | positive regulation of catalytic activity | 29.7297 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 29.7297 | 6 | no |
| GO:0070201 | regulation of establishment of protein localization | 27.0270 | 6 | no |
| GO:0009890 | negative regulation of biosynthetic process | 27.0270 | 5 | no |
| GO:0010468 | regulation of gene expression | 27.0270 | 6 | no |
| GO:0048584 | positive regulation of response to stimulus | 27.0270 | 4 | no |
| GO:0051248 | negative regulation of protein metabolic process | 27.0270 | 6 | no |
| GO:0051338 | regulation of transferase activity | 27.0270 | 4 | no |
| GO:0051052 | regulation of DNA metabolic process | 24.3243 | 5 | no |
| GO:0051054 | positive regulation of DNA metabolic process | 24.3243 | 6 | no |
| GO:1904951 | positive regulation of establishment of protein localization | 24.3243 | 6 | no |
| GO:0008104 | protein localization | 24.3243 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 24.3243 | 5 | no |
| GO:0023056 | positive regulation of signaling | 24.3243 | 4 | no |
| GO:0031327 | negative regulation of cellular biosynthetic process | 24.3243 | 6 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.3243 | 5 | no |
| GO:0006996 | organelle organization | 24.3243 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.3243 | 6 | no |
| GO:0042325 | regulation of phosphorylation | 24.3243 | 7 | no |
| GO:0044087 | regulation of cellular component biogenesis | 24.3243 | 4 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.3243 | 5 | no |
| GO:0051347 | positive regulation of transferase activity | 24.3243 | 5 | no |
| GO:0080134 | regulation of response to stress | 24.3243 | 4 | no |
| GO:0043933 | protein-containing complex organization | 24.3243 | 4 | no |
| GO:0065003 | protein-containing complex assembly | 24.3243 | 5 | no |
| GO:0070202 | regulation of establishment of protein localization to chromosome | 21.6216 | 7 | no |
| GO:0070203 | regulation of establishment of protein localization to telomere | 21.6216 | 7 | no |
| GO:1900180 | regulation of protein localization to nucleus | 21.6216 | 6 | no |
| GO:1900182 | positive regulation of protein localization to nucleus | 21.6216 | 6 | no |
| GO:1904356 | regulation of telomere maintenance via telomere lengthening | 21.6216 | 7 | no |
| GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 21.6216 | 8 | no |
| GO:1904814 | regulation of protein localization to chromosome, telomeric region | 21.6216 | 6 | no |
| GO:1904816 | positive regulation of protein localization to chromosome, telomeric region | 21.6216 | 6 | no |
| GO:1904851 | positive regulation of establishment of protein localization to telomere | 21.6216 | 7 | no |
| GO:1904869 | regulation of protein localization to Cajal body | 21.6216 | 7 | no |
| GO:1904871 | positive regulation of protein localization to Cajal body | 21.6216 | 7 | no |
| GO:1904872 | regulation of telomerase RNA localization to Cajal body | 21.6216 | 4 | no |
| GO:1904874 | positive regulation of telomerase RNA localization to Cajal body | 21.6216 | 4 | no |
| GO:2000278 | regulation of DNA biosynthetic process | 21.6216 | 6 | no |
| GO:2000573 | positive regulation of DNA biosynthetic process | 21.6216 | 7 | no |
| GO:2001252 | positive regulation of chromosome organization | 21.6216 | 7 | no |
| GO:0009894 | regulation of catabolic process | 21.6216 | 4 | no |
| GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.6216 | 6 | no |
| GO:1902531 | regulation of intracellular signal transduction | 21.6216 | 5 | no |
| GO:0001932 | regulation of protein phosphorylation | 21.6216 | 7 | no |
| GO:0031401 | positive regulation of protein modification process | 21.6216 | 7 | no |
| GO:0051493 | regulation of cytoskeleton organization | 21.6216 | 6 | no |
| GO:0048585 | negative regulation of response to stimulus | 21.6216 | 4 | no |
| GO:0031400 | negative regulation of protein modification process | 21.6216 | 7 | no |
| GO:0051049 | regulation of transport | 21.6216 | 4 | no |
| GO:0032101 | regulation of response to external stimulus | 21.6216 | 4 | no |
| GO:0032204 | regulation of telomere maintenance | 21.6216 | 6 | no |
| GO:0032206 | positive regulation of telomere maintenance | 21.6216 | 7 | no |
| GO:0032210 | regulation of telomere maintenance via telomerase | 21.6216 | 7 | no |
| GO:0032212 | positive regulation of telomere maintenance via telomerase | 21.6216 | 8 | no |
| GO:0033044 | regulation of chromosome organization | 21.6216 | 6 | no |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KI21A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| KANK1_HUMAN | [view interactions] | Low throughput | no | yes |
| BIG1_HUMAN | [view interactions] | Low throughput | no | yes |
| ACTT3_HUMAN | [view interactions] | Low throughput | no | no |
| KANK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| DYL1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCPZ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ENDD1_HUMAN | [view interactions] | High throughput | no | yes |
| PFD2_HUMAN | [view interactions] | High throughput | no | yes |
| MSI2H_HUMAN | [view interactions] | High throughput | no | yes |
| PFD1_HUMAN | [view interactions] | High throughput | no | yes |
| TCPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NVL_HUMAN | [view interactions] | High throughput | no | no |
| ZN668_HUMAN | [view interactions] | High throughput | no | yes |
| TCPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPQ_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| UBL4A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TTC9C_HUMAN | [view interactions] | High throughput | no | yes |
| PLXA3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TCPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZN106_HUMAN | [view interactions] | High throughput | no | no |
| RN123_HUMAN | [view interactions] | High throughput | no | yes |
| RFIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TCPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAD51_HUMAN | [view interactions] | High throughput | no | yes |
| TCPG_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RBM4_HUMAN | [view interactions] | High throughput | no | yes |
| TCPE_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | High throughput | no | yes |
| ZDHC5_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DCAF4_HUMAN | [view interactions] | High throughput | no | yes |
| H2B1L_HUMAN | [view interactions] | High throughput | no | yes |
| H31T_HUMAN | [view interactions] | High throughput | no | yes |
| SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
| CALM3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| CDC5L_HUMAN | [view interactions] | High throughput | no | yes |
| FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
| SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| TLK2_HUMAN | [view interactions] | High throughput | no | no |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| ITM2B_HUMAN | [view interactions] | High throughput | no | yes |
| EXOC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DSCAM_HUMAN | [view interactions] | High throughput | no | yes |
| VP26C_HUMAN | [view interactions] | High throughput | no | yes |
| ZNF24_HUMAN | [view interactions] | High throughput | no | yes |
| ELAV1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CALM1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MOV10_HUMAN | [view interactions] | High throughput | no | no |
| NXF1_HUMAN | [view interactions] | High throughput | no | yes |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| M3K4_HUMAN | [view interactions] | High throughput | no | yes |
| TBX3_HUMAN | [view interactions] | High throughput | no | no |
| NCOA4_HUMAN | [view interactions] | High throughput | no | no |
| LIPB1_HUMAN | [view interactions] | High throughput | no | yes |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| TACC2_HUMAN | [view interactions] | High throughput | no | yes |
| NOL8_HUMAN | [view interactions] | High throughput | no | yes |
| KI21B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PHRF1_HUMAN | [view interactions] | High throughput | no | no |
| FIP1_HUMAN | [view interactions] | High throughput | no | yes |
| C99L2_HUMAN | [view interactions] | High throughput | no | yes |
| DGKH_HUMAN | [view interactions] | High throughput | no | yes |
| CF136_HUMAN | [view interactions] | High throughput | no | yes |
| P4HA3_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| GSK3A_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| MYC_HUMAN | [view interactions] | High throughput | no | yes |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| BCAR1_HUMAN | [view interactions] | High throughput | no | yes |
| NONO_HUMAN | [view interactions] | High throughput | no | yes |
| ZBTB2_HUMAN | [view interactions] | High throughput | no | yes |
| PRKN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZRAN1_HUMAN | [view interactions] | High throughput | no | yes |
| HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TRI67_HUMAN | [view interactions] | High throughput | no | no |
| NCS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SRP68_HUMAN | [view interactions] | High throughput | no | yes |
| SRP72_HUMAN | [view interactions] | High throughput | no | yes |
| CHIO_HUMAN | [view interactions] | High throughput | no | yes |
| IMA3_HUMAN | [view interactions] | High throughput | no | yes |
| T2FB_HUMAN | [view interactions] | High throughput | no | yes |
| SYVC_HUMAN | [view interactions] | High throughput | no | yes |
| T2FA_HUMAN | [view interactions] | High throughput | no | yes |
| RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| 5NTC_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF2_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF4_HUMAN | [view interactions] | High throughput | no | yes |
| BPTF_HUMAN | [view interactions] | High throughput | no | yes |
| SRSF6_HUMAN | [view interactions] | High throughput | no | yes |
| HP1B3_HUMAN | [view interactions] | High throughput | no | yes |
| UBR4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PRP8_HUMAN | [view interactions] | High throughput | no | yes |
| CSN6_HUMAN | [view interactions] | High throughput | no | yes |
| USP9X_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| KBP_HUMAN | [view interactions] | High throughput | no | yes |
| CSN4_HUMAN | [view interactions] | High throughput | no | yes |
| ADNP_HUMAN | [view interactions] | High throughput | no | yes |
| CSN3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IMDH2_HUMAN | [view interactions] | High throughput | no | yes |
| MARE3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MLP3B_HUMAN | [view interactions] | High throughput | no | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |