Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

KI21B_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in KI21B_HUMAN
GO:0043168 anion binding 44.8276 4 yes
GO:0000166 nucleotide binding 41.3793 4 yes
GO:0017076 purine nucleotide binding 41.3793 5 yes
GO:0030554 adenyl nucleotide binding 41.3793 6 yes
GO:0032555 purine ribonucleotide binding 41.3793 4 yes
GO:0032559 adenyl ribonucleotide binding 41.3793 5 yes
GO:0005524 ATP binding 37.9310 5 yes
GO:0035639 purine ribonucleoside triphosphate binding 37.9310 4 yes
GO:0016462 pyrophosphatase activity 34.4828 5 yes
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 34.4828 4 yes
GO:0016887 ATP hydrolysis activity 34.4828 7 yes
GO:0017111 ribonucleoside triphosphate phosphatase activity 34.4828 6 yes
GO:0003723 RNA binding 34.4828 4 no
GO:0031625 ubiquitin protein ligase binding 27.5862 5 no
GO:0044389 ubiquitin-like protein ligase binding 27.5862 4 no
GO:0043169 cation binding 24.1379 4 no
GO:0046872 metal ion binding 24.1379 5 no
GO:0015631 tubulin binding 13.7931 4 yes
GO:0008017 microtubule binding 10.3448 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in KI21B_HUMAN
GO:0060255 regulation of macromolecule metabolic process 79.3103 4 no
GO:0080090 regulation of primary metabolic process 79.3103 4 no
GO:0031323 regulation of cellular metabolic process 72.4138 4 no
GO:0048522 positive regulation of cellular process 65.5172 4 no
GO:0009893 positive regulation of metabolic process 62.0690 4 no
GO:0010604 positive regulation of macromolecule metabolic process 62.0690 5 no
GO:0048523 negative regulation of cellular process 51.7241 4 no
GO:0009889 regulation of biosynthetic process 48.2759 4 no
GO:0010556 regulation of macromolecule biosynthetic process 48.2759 5 no
GO:0031325 positive regulation of cellular metabolic process 48.2759 5 no
GO:0031326 regulation of cellular biosynthetic process 48.2759 5 no
GO:0051128 regulation of cellular component organization 48.2759 4 no
GO:0051246 regulation of protein metabolic process 48.2759 5 no
GO:0009892 negative regulation of metabolic process 44.8276 4 no
GO:0010605 negative regulation of macromolecule metabolic process 44.8276 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 41.3793 5 no
GO:0031324 negative regulation of cellular metabolic process 37.9310 5 no
GO:0031399 regulation of protein modification process 37.9310 6 no
GO:0051248 negative regulation of protein metabolic process 37.9310 6 no
GO:0009891 positive regulation of biosynthetic process 34.4828 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 34.4828 6 no
GO:0031328 positive regulation of cellular biosynthetic process 34.4828 6 no
GO:0033043 regulation of organelle organization 34.4828 5 no
GO:0010646 regulation of cell communication 34.4828 4 no
GO:0051247 positive regulation of protein metabolic process 34.4828 6 no
GO:0008104 protein localization 34.4828 4 no
GO:0032880 regulation of protein localization 31.0345 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 31.0345 5 no
GO:0051130 positive regulation of cellular component organization 31.0345 5 no
GO:0060341 regulation of cellular localization 31.0345 4 no
GO:0010638 positive regulation of organelle organization 27.5862 6 no
GO:0033044 regulation of chromosome organization 27.5862 6 no
GO:0050821 protein stabilization 27.5862 4 no
GO:0051052 regulation of DNA metabolic process 27.5862 5 no
GO:0051054 positive regulation of DNA metabolic process 27.5862 6 no
GO:0070201 regulation of establishment of protein localization 27.5862 6 no
GO:1903829 positive regulation of protein localization 27.5862 5 no
GO:1904951 positive regulation of establishment of protein localization 27.5862 6 no
GO:0009966 regulation of signal transduction 27.5862 4 no
GO:0019220 regulation of phosphate metabolic process 27.5862 6 no
GO:0031401 positive regulation of protein modification process 27.5862 7 no
GO:0051049 regulation of transport 27.5862 4 no
GO:0051174 regulation of phosphorus metabolic process 27.5862 5 no
GO:0032204 regulation of telomere maintenance 24.1379 6 no
GO:0032206 positive regulation of telomere maintenance 24.1379 7 no
GO:0032210 regulation of telomere maintenance via telomerase 24.1379 7 no
GO:0032212 positive regulation of telomere maintenance via telomerase 24.1379 8 no
GO:0070202 regulation of establishment of protein localization to chromosome 24.1379 7 no
GO:0070203 regulation of establishment of protein localization to telomere 24.1379 7 no
GO:1900180 regulation of protein localization to nucleus 24.1379 6 no
GO:1900182 positive regulation of protein localization to nucleus 24.1379 6 no
GO:1904356 regulation of telomere maintenance via telomere lengthening 24.1379 7 no
GO:1904358 positive regulation of telomere maintenance via telomere lengthening 24.1379 8 no
GO:1904814 regulation of protein localization to chromosome, telomeric region 24.1379 6 no
GO:1904816 positive regulation of protein localization to chromosome, telomeric region 24.1379 6 no
GO:1904851 positive regulation of establishment of protein localization to telomere 24.1379 7 no
GO:1904869 regulation of protein localization to Cajal body 24.1379 7 no
GO:1904871 positive regulation of protein localization to Cajal body 24.1379 7 no
GO:1904872 regulation of telomerase RNA localization to Cajal body 24.1379 4 no
GO:1904874 positive regulation of telomerase RNA localization to Cajal body 24.1379 4 no
GO:2000278 regulation of DNA biosynthetic process 24.1379 6 no
GO:2000573 positive regulation of DNA biosynthetic process 24.1379 7 no
GO:2001252 positive regulation of chromosome organization 24.1379 7 no
GO:0021762 substantia nigra development 24.1379 4 no
GO:0034762 regulation of transmembrane transport 24.1379 4 no
GO:0034765 regulation of monoatomic ion transmembrane transport 24.1379 5 no
GO:0043085 positive regulation of catalytic activity 24.1379 4 no
GO:0043269 regulation of monoatomic ion transport 24.1379 5 no
GO:0051338 regulation of transferase activity 24.1379 4 no
GO:0010468 regulation of gene expression 24.1379 6 no
GO:0043412 macromolecule modification 24.1379 4 no
GO:0022607 cellular component assembly 24.1379 4 no
GO:0001932 regulation of protein phosphorylation 20.6897 7 no
GO:0010563 negative regulation of phosphorus metabolic process 20.6897 6 no
GO:0010959 regulation of metal ion transport 20.6897 6 no
GO:0022898 regulation of transmembrane transporter activity 20.6897 4 no
GO:0031400 negative regulation of protein modification process 20.6897 7 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 20.6897 5 no
GO:0034763 negative regulation of transmembrane transport 20.6897 5 no
GO:0034766 negative regulation of monoatomic ion transmembrane transport 20.6897 6 no
GO:0042325 regulation of phosphorylation 20.6897 7 no
GO:0043271 negative regulation of monoatomic ion transport 20.6897 5 no
GO:0045936 negative regulation of phosphate metabolic process 20.6897 7 no
GO:0051051 negative regulation of transport 20.6897 4 no
GO:0051347 positive regulation of transferase activity 20.6897 5 no
GO:0141124 intracellular signaling cassette 20.6897 4 no
GO:1902531 regulation of intracellular signal transduction 20.6897 5 no
GO:1904062 regulation of monoatomic cation transmembrane transport 20.6897 6 no
GO:0036211 protein modification process 20.6897 4 no
GO:0006605 protein targeting 20.6897 4 no
GO:0007339 binding of sperm to zona pellucida 20.6897 5 no
GO:0035036 sperm-egg recognition 20.6897 4 no
GO:0043933 protein-containing complex organization 20.6897 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
TRIM3_HUMAN [view entry] [view interactions] Low throughput yes no
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
MED4_HUMAN [view interactions] High throughput no yes
WDR75_HUMAN [view interactions] High throughput no no
TM248_HUMAN [view interactions] High throughput no yes
USF1_HUMAN [view interactions] High throughput no yes
ZN281_HUMAN [view interactions] High throughput no no
HAUS2_HUMAN [view interactions] High throughput no yes
1433T_HUMAN [view entry] [view interactions] High throughput yes yes
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
CALM3_HUMAN [view entry] [view interactions] High throughput yes yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
MYOME_HUMAN [view interactions] High throughput no no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
DYR1A_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
NUDC_HUMAN [view interactions] High throughput no yes
NECD_HUMAN [view interactions] High throughput no no
NTAQ1_HUMAN [view interactions] High throughput no yes
QKI_HUMAN [view interactions] High throughput no no
DMRTB_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
CALM1_HUMAN [view entry] [view interactions] High throughput yes yes
CAPG_HUMAN [view entry] [view interactions] High throughput yes no
CSTF2_HUMAN [view interactions] High throughput no yes
TAF12_HUMAN [view interactions] High throughput no yes
TBX3_HUMAN [view interactions] High throughput no no
BAG6_HUMAN [view entry] [view interactions] High throughput yes yes
HNRPQ_HUMAN [view entry] [view interactions] High throughput yes yes
KI21A_HUMAN [view entry] [view interactions] High throughput yes yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
TP4A1_HUMAN [view interactions] High throughput no no
TP4A2_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
GAN_HUMAN [view interactions] High throughput no yes
PMF1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
ACK1_HUMAN [view entry] [view interactions] High throughput yes yes
NUPR1_HUMAN [view interactions] High throughput no no
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
PFD6_HUMAN [view interactions] High throughput no yes
TBB4B_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
LDLR_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
KITH_HUMAN [view interactions] High throughput no yes
OXND1_HUMAN [view interactions] High throughput no yes
TAF5_HUMAN [view interactions] High throughput no yes
FUBP3_HUMAN [view interactions] High throughput no yes
TCAM1_HUMAN [view interactions] High throughput no yes
P3H1_HUMAN [view interactions] High throughput no yes
PRP6_HUMAN [view interactions] High throughput no yes
CPSF1_HUMAN [view interactions] High throughput no no
CPSF3_HUMAN [view interactions] High throughput no yes
CO4A5_HUMAN [view interactions] High throughput no no
CPSF5_HUMAN [view interactions] High throughput no yes
BTD_HUMAN [view interactions] High throughput no no
DPOE3_HUMAN [view interactions] High throughput no yes