TRIM3_HUMAN
Probably involved in vesicular trafficking via its association with the CART complex (PubMed). The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed). Positively regulates motility of microtubule-dependent motor protein KIF21B . [View more on UniProt]
Interacting region for partners were not defined.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in TRIM3_HUMAN |
---|---|---|---|---|
GO:0003723 | RNA binding | 39.3939 | 4 | no |
GO:0017076 | purine nucleotide binding | 27.2727 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 27.2727 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 27.2727 | 4 | no |
GO:0046872 | metal ion binding | 24.2424 | 4 | yes |
GO:0005524 | ATP binding | 24.2424 | 5 | no |
GO:0030554 | adenyl nucleotide binding | 24.2424 | 5 | no |
GO:0032559 | adenyl ribonucleotide binding | 24.2424 | 5 | no |
GO:0004842 | ubiquitin-protein transferase activity | 15.1515 | 4 | yes |
GO:0008270 | zinc ion binding | 15.1515 | 6 | yes |
GO:0046914 | transition metal ion binding | 15.1515 | 5 | yes |
GO:0061630 | ubiquitin protein ligase activity | 15.1515 | 5 | yes |
GO:0061659 | ubiquitin-like protein ligase activity | 15.1515 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in TRIM3_HUMAN |
---|---|---|---|---|
GO:0051171 | regulation of nitrogen compound metabolic process | 69.6970 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 69.6970 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 69.6970 | 4 | no |
GO:0031323 | regulation of cellular metabolic process | 63.6364 | 4 | no |
GO:0048522 | positive regulation of cellular process | 60.6061 | 4 | no |
GO:0010468 | regulation of gene expression | 57.5758 | 5 | no |
GO:0010646 | regulation of cell communication | 51.5152 | 4 | no |
GO:0051246 | regulation of protein metabolic process | 51.5152 | 5 | no |
GO:0009893 | positive regulation of metabolic process | 48.4848 | 4 | no |
GO:0009966 | regulation of signal transduction | 45.4545 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 45.4545 | 5 | no |
GO:0031399 | regulation of protein modification process | 42.4242 | 6 | no |
GO:0048523 | negative regulation of cellular process | 42.4242 | 4 | no |
GO:0051128 | regulation of cellular component organization | 42.4242 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 42.4242 | 5 | no |
GO:0009889 | regulation of biosynthetic process | 42.4242 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 42.4242 | 5 | no |
GO:0031326 | regulation of cellular biosynthetic process | 42.4242 | 5 | no |
GO:0036211 | protein modification process | 39.3939 | 4 | yes |
GO:0043412 | macromolecule modification | 39.3939 | 4 | yes |
GO:0006996 | organelle organization | 39.3939 | 4 | no |
GO:0051247 | positive regulation of protein metabolic process | 39.3939 | 6 | no |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 39.3939 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 36.3636 | 6 | no |
GO:0031325 | positive regulation of cellular metabolic process | 36.3636 | 5 | no |
GO:0042325 | regulation of phosphorylation | 36.3636 | 7 | no |
GO:0051174 | regulation of phosphorus metabolic process | 36.3636 | 5 | no |
GO:0051252 | regulation of RNA metabolic process | 36.3636 | 5 | no |
GO:0071702 | organic substance transport | 33.3333 | 4 | yes |
GO:0071705 | nitrogen compound transport | 33.3333 | 4 | yes |
GO:0009894 | regulation of catabolic process | 33.3333 | 4 | no |
GO:0022607 | cellular component assembly | 33.3333 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 33.3333 | 7 | no |
GO:0048584 | positive regulation of response to stimulus | 33.3333 | 4 | no |
GO:0008104 | protein localization | 30.3030 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 30.3030 | 4 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 30.3030 | 5 | no |
GO:0045595 | regulation of cell differentiation | 30.3030 | 4 | no |
GO:0031401 | positive regulation of protein modification process | 30.3030 | 7 | no |
GO:0010647 | positive regulation of cell communication | 30.3030 | 5 | no |
GO:0023056 | positive regulation of signaling | 30.3030 | 4 | no |
GO:0007010 | cytoskeleton organization | 27.2727 | 5 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 27.2727 | 6 | no |
GO:0030030 | cell projection organization | 27.2727 | 4 | no |
GO:0031324 | negative regulation of cellular metabolic process | 27.2727 | 5 | no |
GO:0031329 | regulation of cellular catabolic process | 27.2727 | 5 | no |
GO:0031344 | regulation of cell projection organization | 27.2727 | 5 | no |
GO:0042327 | positive regulation of phosphorylation | 27.2727 | 8 | no |
GO:0044087 | regulation of cellular component biogenesis | 27.2727 | 4 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 27.2727 | 7 | no |
GO:0050804 | modulation of chemical synaptic transmission | 27.2727 | 5 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 27.2727 | 5 | no |
GO:0099177 | regulation of trans-synaptic signaling | 27.2727 | 4 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 27.2727 | 6 | no |
GO:1902531 | regulation of intracellular signal transduction | 27.2727 | 5 | no |
GO:0051049 | regulation of transport | 27.2727 | 4 | no |
GO:0015031 | protein transport | 24.2424 | 4 | yes |
GO:0010941 | regulation of cell death | 24.2424 | 4 | no |
GO:0051130 | positive regulation of cellular component organization | 24.2424 | 5 | no |
GO:0080134 | regulation of response to stress | 24.2424 | 4 | no |
GO:0001934 | positive regulation of protein phosphorylation | 24.2424 | 8 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 24.2424 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 24.2424 | 6 | no |
GO:0016192 | vesicle-mediated transport | 24.2424 | 4 | no |
GO:0006796 | phosphate-containing compound metabolic process | 24.2424 | 4 | no |
GO:0033043 | regulation of organelle organization | 21.2121 | 5 | no |
GO:0044089 | positive regulation of cellular component biogenesis | 21.2121 | 5 | no |
GO:0051248 | negative regulation of protein metabolic process | 21.2121 | 6 | no |
GO:0080135 | regulation of cellular response to stress | 21.2121 | 4 | no |
GO:0120036 | plasma membrane bounded cell projection organization | 21.2121 | 5 | no |
GO:0009890 | negative regulation of biosynthetic process | 21.2121 | 5 | no |
GO:0010558 | negative regulation of macromolecule biosynthetic process | 21.2121 | 6 | no |
GO:0031327 | negative regulation of cellular biosynthetic process | 21.2121 | 6 | no |
GO:0006355 | regulation of DNA-templated transcription | 21.2121 | 6 | no |
GO:0009057 | macromolecule catabolic process | 18.1818 | 4 | yes |
GO:0032446 | protein modification by small protein conjugation | 18.1818 | 6 | yes |
GO:0044265 | cellular macromolecule catabolic process | 18.1818 | 4 | yes |
GO:0070647 | protein modification by small protein conjugation or removal | 18.1818 | 5 | yes |
GO:0000209 | protein polyubiquitination | 15.1515 | 8 | yes |
GO:0006508 | proteolysis | 15.1515 | 4 | yes |
GO:0006511 | ubiquitin-dependent protein catabolic process | 15.1515 | 7 | yes |
GO:0010498 | proteasomal protein catabolic process | 15.1515 | 5 | yes |
GO:0016567 | protein ubiquitination | 15.1515 | 7 | yes |
GO:0019941 | modification-dependent protein catabolic process | 15.1515 | 6 | yes |
GO:0030163 | protein catabolic process | 15.1515 | 4 | yes |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 15.1515 | 6 | yes |
GO:0043632 | modification-dependent macromolecule catabolic process | 15.1515 | 5 | yes |
GO:0051603 | proteolysis involved in protein catabolic process | 15.1515 | 5 | yes |
GO:1901565 | organonitrogen compound catabolic process | 15.1515 | 4 | yes |
GO:0007399 | nervous system development | 12.1212 | 4 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
MYO5B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UB2D1_HUMAN | [view interactions] | Low throughput | no | yes |
ACTN4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KI21B_HUMAN | [view interactions] | Low throughput | no | yes |
UBC9_HUMAN | [view interactions] | Low throughput | no | yes |
LST2_HUMAN | [view interactions] | Low throughput | no | yes |
HGS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MYO5A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
CDN1A_HUMAN | [view interactions] | Low throughput | no | no |
IMB1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NOTC1_HUMAN | [view interactions] | Low throughput | no | yes |
IMA3_HUMAN | [view interactions] | Low throughput | no | yes |
BECN1_HUMAN | [view interactions] | Low throughput | no | yes |
P53_HUMAN | [view interactions] | Low throughput | no | no |
ESR1_HUMAN | [view interactions] | Low throughput | no | no |
SAE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UB2D2_HUMAN | [view interactions] | Low throughput | no | yes |
UB2E1_HUMAN | [view interactions] | Low throughput | no | yes |
TRPM7_HUMAN | [view interactions] | High throughput | no | no |
TRIM2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FMR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HUWE1_HUMAN | [view interactions] | High throughput | no | yes |
MYOME_HUMAN | [view interactions] | High throughput | no | no |
TNIK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TSC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UB2G2_HUMAN | [view interactions] | High throughput | no | yes |
UBE2U_HUMAN | [view interactions] | High throughput | no | no |
LNX1_HUMAN | [view interactions] | High throughput | no | yes |
RO52_HUMAN | [view interactions] | High throughput | no | yes |
UB2E2_HUMAN | [view interactions] | High throughput | no | yes |
LRC8E_HUMAN | [view interactions] | High throughput | no | no |
CEP70_HUMAN | [view interactions] | High throughput | no | yes |
KC1E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ARLY_HUMAN | [view interactions] | High throughput | no | no |
KC1D_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TRIM3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
UBE2Z_HUMAN | [view interactions] | High throughput | no | yes |
ROP1A_HUMAN | [view interactions] | High throughput | no | no |
DNMT1_HUMAN | [view interactions] | High throughput | no | no |
FXR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FXR2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TEAD2_HUMAN | [view interactions] | High throughput | no | no |
UB2D4_HUMAN | [view interactions] | High throughput | no | yes |
TNAP3_HUMAN | [view interactions] | High throughput | no | yes |
UBP32_HUMAN | [view interactions] | High throughput | no | yes |
TEAD1_HUMAN | [view interactions] | High throughput | no | no |
KCTD7_HUMAN | [view interactions] | High throughput | no | no |
HECW2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
CUL3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
OXDA_HUMAN | [view interactions] | High throughput | no | no |
PRP6_HUMAN | [view interactions] | High throughput | no | yes |
DDX17_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
U2AF2_HUMAN | [view interactions] | High throughput | no | yes |
PAIRB_HUMAN | [view interactions] | High throughput | no | yes |
RL6_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PABP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RGS14_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
DPYL2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
INS_HUMAN | [view interactions] | High throughput | no | no |
MK01_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCC2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DX39A_HUMAN | [view interactions] | High throughput | no | yes |
GPM6A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TMIE_HUMAN | [view interactions] | High throughput | no | yes |
EMC4_HUMAN | [view interactions] | High throughput | no | yes |
RASK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ODPA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCDN_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
UBE2K_HUMAN | [view interactions] | High throughput | no | yes |