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NOTC1_HUMAN

Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4(+) and CD8(+) cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI001401 DEG_SCF_FBW7_2 DEG 2508 2515 -
ELMI002029 DOC_WW_Pin1_4 DOC 2118 2123 -
ELMI002030 DOC_WW_Pin1_4 DOC 2129 2134 -
ELMI002031 DOC_WW_Pin1_4 DOC 2133 2138 -
ELMI002957 LIG_CSL_BTD_1 LIG 1767 1770 -
ELMI001401 DEG_SCF_FBW7_2 DEG 2508 2515 -
ELMI002029 DOC_WW_Pin1_4 DOC 2118 2123 -
ELMI002030 DOC_WW_Pin1_4 DOC 2129 2134 -
ELMI002031 DOC_WW_Pin1_4 DOC 2133 2138 -
ELMI002957 LIG_CSL_BTD_1 LIG 1767 1770 -

Molecular function

Term Name % Distance from the top of the tree Annotated in NOTC1_HUMAN
GO:0000166 nucleotide binding 38.3178 4 no
GO:0043168 anion binding 38.3178 4 no
GO:0017076 purine nucleotide binding 37.3832 5 no
GO:0032555 purine ribonucleotide binding 36.4486 4 no
GO:0035639 purine ribonucleoside triphosphate binding 36.4486 4 no
GO:0016462 pyrophosphatase activity 24.2991 5 no
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 24.2991 4 no
GO:0017111 ribonucleoside triphosphate phosphatase activity 24.2991 6 no
GO:0043169 cation binding 22.4299 4 yes
GO:0046872 metal ion binding 22.4299 5 yes
GO:0019900 kinase binding 22.4299 4 no
GO:0019901 protein kinase binding 21.4953 5 no
GO:0030554 adenyl nucleotide binding 20.5607 6 no
GO:0003677 DNA binding 9.3458 4 yes
GO:0003690 double-stranded DNA binding 7.4766 5 yes
GO:0043565 sequence-specific DNA binding 5.6075 5 yes
GO:1990837 sequence-specific double-stranded DNA binding 5.6075 6 yes
GO:0000976 transcription cis-regulatory region binding 4.6729 5 yes
GO:0000987 cis-regulatory region sequence-specific DNA binding 4.6729 6 yes
GO:0001067 transcription regulatory region nucleic acid binding 4.6729 4 yes
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3.7383 4 yes
GO:0005509 calcium ion binding 3.7383 6 yes
GO:0005112 Notch binding 2.8037 4 yes
GO:0031490 chromatin DNA binding 2.8037 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in NOTC1_HUMAN
GO:0048522 positive regulation of cellular process 71.0280 4 yes
GO:0060255 regulation of macromolecule metabolic process 63.5514 4 yes
GO:0048523 negative regulation of cellular process 59.8131 4 yes
GO:0080090 regulation of primary metabolic process 58.8785 4 yes
GO:0031323 regulation of cellular metabolic process 56.0748 4 yes
GO:0010646 regulation of cell communication 55.1402 4 yes
GO:0051128 regulation of cellular component organization 55.1402 4 yes
GO:0009893 positive regulation of metabolic process 54.2056 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 53.2710 5 yes
GO:0009966 regulation of signal transduction 51.4019 4 yes
GO:0009889 regulation of biosynthetic process 49.5327 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 49.5327 5 yes
GO:0031326 regulation of cellular biosynthetic process 49.5327 5 yes
GO:0006996 organelle organization 46.7290 4 yes
GO:0048584 positive regulation of response to stimulus 45.7944 4 yes
GO:0051246 regulation of protein metabolic process 44.8598 5 no
GO:0010468 regulation of gene expression 43.9252 6 yes
GO:0022607 cellular component assembly 43.9252 4 yes
GO:0031325 positive regulation of cellular metabolic process 42.9907 5 yes
GO:0008104 protein localization 42.0561 4 yes
GO:0051049 regulation of transport 41.1215 4 yes
GO:0043412 macromolecule modification 40.1869 4 no
GO:0023056 positive regulation of signaling 39.2523 4 yes
GO:1902531 regulation of intracellular signal transduction 39.2523 5 yes
GO:0036211 protein modification process 39.2523 4 no
GO:0009892 negative regulation of metabolic process 38.3178 4 yes
GO:0010647 positive regulation of cell communication 38.3178 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 38.3178 5 yes
GO:0009891 positive regulation of biosynthetic process 37.3832 5 yes
GO:0031328 positive regulation of cellular biosynthetic process 37.3832 6 yes
GO:0009967 positive regulation of signal transduction 36.4486 5 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 36.4486 6 yes
GO:0010605 negative regulation of macromolecule metabolic process 35.5140 5 yes
GO:0031324 negative regulation of cellular metabolic process 35.5140 5 yes
GO:0051247 positive regulation of protein metabolic process 35.5140 6 no
GO:0031399 regulation of protein modification process 34.5794 6 no
GO:0060341 regulation of cellular localization 32.7103 4 no
GO:0051252 regulation of RNA metabolic process 31.7757 5 yes
GO:0042127 regulation of cell population proliferation 31.7757 4 yes
GO:0045595 regulation of cell differentiation 31.7757 4 yes
GO:0030030 cell projection organization 30.8411 4 yes
GO:0042981 regulation of apoptotic process 30.8411 5 yes
GO:0043067 regulation of programmed cell death 30.8411 4 yes
GO:0044087 regulation of cellular component biogenesis 30.8411 4 yes
GO:0071702 organic substance transport 29.9065 4 yes
GO:0071705 nitrogen compound transport 29.9065 4 yes
GO:2001141 regulation of RNA biosynthetic process 29.9065 6 yes
GO:0032880 regulation of protein localization 29.9065 5 no
GO:0051130 positive regulation of cellular component organization 29.9065 5 no
GO:0048585 negative regulation of response to stimulus 29.9065 4 yes
GO:0006355 regulation of DNA-templated transcription 29.9065 7 yes
GO:0010648 negative regulation of cell communication 28.9720 5 yes
GO:0023057 negative regulation of signaling 28.9720 4 yes
GO:2000145 regulation of cell motility 28.9720 4 yes
GO:0019220 regulation of phosphate metabolic process 28.9720 6 no
GO:0051174 regulation of phosphorus metabolic process 28.9720 5 no
GO:0033043 regulation of organelle organization 28.9720 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 28.9720 5 yes
GO:0009968 negative regulation of signal transduction 28.0374 5 yes
GO:0071310 cellular response to organic substance 28.0374 4 yes
GO:0030334 regulation of cell migration 28.0374 5 yes
GO:0015031 protein transport 27.1028 4 yes
GO:1902533 positive regulation of intracellular signal transduction 27.1028 6 yes
GO:0009894 regulation of catabolic process 27.1028 4 no
GO:0042325 regulation of phosphorylation 27.1028 7 no
GO:0051240 positive regulation of multicellular organismal process 26.1682 4 yes
GO:0002684 positive regulation of immune system process 26.1682 4 no
GO:2000026 regulation of multicellular organismal development 25.2336 4 yes
GO:0001932 regulation of protein phosphorylation 25.2336 7 no
GO:0051050 positive regulation of transport 25.2336 4 no
GO:0051094 positive regulation of developmental process 25.2336 4 yes
GO:0008284 positive regulation of cell population proliferation 24.2991 5 yes
GO:0009890 negative regulation of biosynthetic process 24.2991 5 yes
GO:0030155 regulation of cell adhesion 24.2991 4 yes
GO:0031401 positive regulation of protein modification process 24.2991 7 no
GO:0031344 regulation of cell projection organization 24.2991 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 24.2991 6 no
GO:0010558 negative regulation of macromolecule biosynthetic process 23.3645 6 yes
GO:0060627 regulation of vesicle-mediated transport 23.3645 4 yes
GO:0120036 plasma membrane bounded cell projection organization 23.3645 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 23.3645 6 yes
GO:0043933 protein-containing complex organization 23.3645 4 no
GO:0141124 intracellular signaling cassette 23.3645 4 no
GO:1901701 cellular response to oxygen-containing compound 23.3645 4 no
GO:0006357 regulation of transcription by RNA polymerase II 23.3645 8 yes
GO:0006915 apoptotic process 23.3645 4 yes
GO:0051254 positive regulation of RNA metabolic process 22.4299 6 yes
GO:0060284 regulation of cell development 22.4299 5 yes
GO:0032101 regulation of response to external stimulus 22.4299 4 yes
GO:0007010 cytoskeleton organization 22.4299 5 no
GO:0043687 post-translational protein modification 22.4299 5 no
GO:0051241 negative regulation of multicellular organismal process 21.4953 4 yes
GO:0010628 positive regulation of gene expression 21.4953 7 yes
GO:0022603 regulation of anatomical structure morphogenesis 21.4953 4 yes
GO:0030335 positive regulation of cell migration 21.4953 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 21.4953 7 yes
GO:0040017 positive regulation of locomotion 21.4953 4 yes
GO:2000147 positive regulation of cell motility 21.4953 5 yes
GO:0080134 regulation of response to stress 21.4953 4 no
GO:1903829 positive regulation of protein localization 21.4953 5 no
GO:0045893 positive regulation of DNA-templated transcription 21.4953 8 yes
GO:0006508 proteolysis 21.4953 4 no
GO:0009057 macromolecule catabolic process 20.5607 4 yes
GO:0043066 negative regulation of apoptotic process 20.5607 6 yes
GO:0043069 negative regulation of programmed cell death 20.5607 5 yes
GO:0045597 positive regulation of cell differentiation 20.5607 5 yes
GO:0050776 regulation of immune response 20.5607 4 no
GO:0051248 negative regulation of protein metabolic process 20.5607 6 no
GO:0010562 positive regulation of phosphorus metabolic process 20.5607 6 no
GO:0045937 positive regulation of phosphate metabolic process 20.5607 7 no
GO:0070647 protein modification by small protein conjugation or removal 20.5607 6 no
GO:0010243 response to organonitrogen compound 19.6262 4 yes
GO:0010629 negative regulation of gene expression 18.6916 7 yes
GO:0031175 neuron projection development 18.6916 6 yes
GO:0043408 regulation of MAPK cascade 18.6916 6 yes
GO:0051129 negative regulation of cellular component organization 18.6916 5 yes
GO:0006886 intracellular protein transport 18.6916 4 yes
GO:0033365 protein localization to organelle 17.7570 5 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 17.7570 9 yes
GO:0051093 negative regulation of developmental process 17.7570 4 yes
GO:0070925 organelle assembly 16.8224 5 yes
GO:0030163 protein catabolic process 14.9533 4 yes
GO:0090304 nucleic acid metabolic process 14.9533 4 yes
GO:1901565 organonitrogen compound catabolic process 14.9533 4 yes
GO:0033993 response to lipid 14.9533 4 yes
GO:0043068 positive regulation of programmed cell death 14.9533 5 yes
GO:0010720 positive regulation of cell development 14.0187 6 yes
GO:0022407 regulation of cell-cell adhesion 14.0187 5 yes
GO:0043065 positive regulation of apoptotic process 14.0187 6 yes
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 14.0187 5 yes
GO:0051960 regulation of nervous system development 13.0841 5 yes
GO:0043086 negative regulation of catalytic activity 13.0841 4 yes
GO:0051046 regulation of secretion 13.0841 5 yes
GO:0051253 negative regulation of RNA metabolic process 12.1495 6 yes
GO:0009059 macromolecule biosynthetic process 12.1495 4 yes
GO:1902679 negative regulation of RNA biosynthetic process 12.1495 7 yes
GO:1903530 regulation of secretion by cell 12.1495 4 yes
GO:0043410 positive regulation of MAPK cascade 12.1495 7 yes
GO:0044057 regulation of system process 12.1495 4 yes
GO:0045596 negative regulation of cell differentiation 12.1495 5 yes
GO:0045892 negative regulation of DNA-templated transcription 12.1495 8 yes
GO:0000122 negative regulation of transcription by RNA polymerase II 12.1495 9 yes
GO:0050767 regulation of neurogenesis 12.1495 6 yes
GO:0051051 negative regulation of transport 12.1495 4 yes
GO:0008285 negative regulation of cell population proliferation 11.2150 5 yes
GO:0016070 RNA metabolic process 11.2150 5 yes
GO:0030031 cell projection assembly 11.2150 5 yes
GO:0030111 regulation of Wnt signaling pathway 11.2150 5 yes
GO:0072594 establishment of protein localization to organelle 11.2150 4 yes
GO:0040013 negative regulation of locomotion 11.2150 4 yes
GO:0010632 regulation of epithelial cell migration 10.2804 4 yes
GO:0010810 regulation of cell-substrate adhesion 10.2804 5 yes
GO:0071363 cellular response to growth factor stimulus 10.2804 4 yes
GO:0090287 regulation of cellular response to growth factor stimulus 10.2804 4 yes
GO:0032870 cellular response to hormone stimulus 10.2804 4 yes
GO:2000146 negative regulation of cell motility 10.2804 5 yes
GO:0002009 morphogenesis of an epithelium 10.2804 4 yes
GO:0048638 regulation of developmental growth 10.2804 4 yes
GO:0048732 gland development 10.2804 4 yes
GO:0051056 regulation of small GTPase mediated signal transduction 10.2804 6 yes
GO:0051962 positive regulation of nervous system development 9.3458 5 yes
GO:0070372 regulation of ERK1 and ERK2 cascade 9.3458 7 yes
GO:0017157 regulation of exocytosis 9.3458 5 yes
GO:0030336 negative regulation of cell migration 9.3458 6 yes
GO:0045664 regulation of neuron differentiation 9.3458 5 yes
GO:0001894 tissue homeostasis 9.3458 4 yes
GO:0050678 regulation of epithelial cell proliferation 9.3458 5 yes
GO:0050769 positive regulation of neurogenesis 9.3458 6 yes
GO:0050920 regulation of chemotaxis 9.3458 4 yes
GO:0009792 embryo development ending in birth or egg hatching 8.4112 4 yes
GO:0060562 epithelial tube morphogenesis 8.4112 4 yes
GO:0010721 negative regulation of cell development 8.4112 6 yes
GO:0030182 neuron differentiation 8.4112 4 yes
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 8.4112 5 yes
GO:0120031 plasma membrane bounded cell projection assembly 8.4112 6 yes
GO:0036293 response to decreased oxygen levels 8.4112 4 yes
GO:0043009 chordate embryonic development 8.4112 5 yes
GO:0001701 in utero embryonic development 8.4112 6 yes
GO:0050679 positive regulation of epithelial cell proliferation 8.4112 6 yes
GO:0007162 negative regulation of cell adhesion 8.4112 5 yes
GO:0007219 Notch signaling pathway 8.4112 4 yes
GO:0010594 regulation of endothelial cell migration 7.4766 5 yes
GO:0060828 regulation of canonical Wnt signaling pathway 7.4766 6 yes
GO:0030855 epithelial cell differentiation 7.4766 4 yes
GO:0032102 negative regulation of response to external stimulus 7.4766 5 yes
GO:1903305 regulation of regulated secretory pathway 7.4766 6 yes
GO:0045927 positive regulation of growth 7.4766 4 yes
GO:0006954 inflammatory response 7.4766 4 yes
GO:0007411 axon guidance 6.5421 8 yes
GO:0051961 negative regulation of nervous system development 6.5421 5 yes
GO:0070374 positive regulation of ERK1 and ERK2 cascade 6.5421 8 yes
GO:0071453 cellular response to oxygen levels 6.5421 4 yes
GO:0090257 regulation of muscle system process 6.5421 5 yes
GO:0097485 neuron projection guidance 6.5421 7 yes
GO:0141187 nucleic acid biosynthetic process 6.5421 5 yes
GO:1901362 organic cyclic compound biosynthetic process 6.5421 4 yes
GO:0034504 protein localization to nucleus 6.5421 6 yes
GO:0034654 nucleobase-containing compound biosynthetic process 6.5421 4 yes
GO:0036294 cellular response to decreased oxygen levels 6.5421 5 yes
GO:0046903 secretion 6.5421 4 yes
GO:0050768 negative regulation of neurogenesis 6.5421 6 yes
GO:0051169 nuclear transport 5.6075 4 yes
GO:0051170 import into nucleus 5.6075 6 yes
GO:0007507 heart development 5.6075 4 yes
GO:0010001 glial cell differentiation 5.6075 4 yes
GO:0060429 epithelium development 5.6075 4 yes
GO:0060537 muscle tissue development 5.6075 4 yes
GO:0014013 regulation of gliogenesis 5.6075 7 yes
GO:0019221 cytokine-mediated signaling pathway 5.6075 4 yes
GO:0022408 negative regulation of cell-cell adhesion 5.6075 6 yes
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 5.6075 6 yes
GO:0032496 response to lipopolysaccharide 5.6075 4 yes
GO:0032774 RNA biosynthetic process 5.6075 5 yes
GO:2000177 regulation of neural precursor cell proliferation 5.6075 5 yes
GO:0001837 epithelial to mesenchymal transition 5.6075 5 yes
GO:0001947 heart looping 5.6075 5 yes
GO:0002237 response to molecule of bacterial origin 5.6075 4 yes
GO:0003143 embryonic heart tube morphogenesis 5.6075 4 yes
GO:0048762 mesenchymal cell differentiation 5.6075 4 yes
GO:0006351 DNA-templated transcription 5.6075 6 yes
GO:0051057 positive regulation of small GTPase mediated signal transduction 5.6075 7 yes
GO:0006606 protein import into nucleus 5.6075 5 yes
GO:0051147 regulation of muscle cell differentiation 5.6075 5 yes
GO:0006913 nucleocytoplasmic transport 5.6075 5 yes
GO:0051149 positive regulation of muscle cell differentiation 5.6075 6 yes
GO:0008593 regulation of Notch signaling pathway 4.6729 5 yes
GO:0010633 negative regulation of epithelial cell migration 4.6729 5 yes
GO:0010717 regulation of epithelial to mesenchymal transition 4.6729 5 yes
GO:0014015 positive regulation of gliogenesis 4.6729 7 yes
GO:0014706 striated muscle tissue development 4.6729 5 yes
GO:0071456 cellular response to hypoxia 4.6729 4 yes
GO:0030326 embryonic limb morphogenesis 4.6729 5 yes
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4.6729 6 yes
GO:0090288 negative regulation of cellular response to growth factor stimulus 4.6729 5 yes
GO:0030856 regulation of epithelial cell differentiation 4.6729 5 yes
GO:0035108 limb morphogenesis 4.6729 4 yes
GO:1903531 negative regulation of secretion by cell 4.6729 5 yes
GO:0035113 embryonic appendage morphogenesis 4.6729 4 yes
GO:1904892 regulation of receptor signaling pathway via STAT 4.6729 5 yes
GO:2000179 positive regulation of neural precursor cell proliferation 4.6729 6 yes
GO:2000736 regulation of stem cell differentiation 4.6729 5 yes
GO:0043535 regulation of blood vessel endothelial cell migration 4.6729 6 yes
GO:0045445 myoblast differentiation 4.6729 4 yes
GO:0045665 negative regulation of neuron differentiation 4.6729 6 yes
GO:0046425 regulation of receptor signaling pathway via JAK-STAT 4.6729 6 yes
GO:0001889 liver development 4.6729 5 yes
GO:0048639 positive regulation of developmental growth 4.6729 5 yes
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 4.6729 4 yes
GO:0048738 cardiac muscle tissue development 4.6729 6 yes
GO:0048754 branching morphogenesis of an epithelial tube 4.6729 4 yes
GO:0051048 negative regulation of secretion 4.6729 5 yes
GO:0006366 transcription by RNA polymerase II 4.6729 7 yes
GO:0009952 anterior/posterior pattern specification 3.7383 4 yes
GO:0060251 regulation of glial cell proliferation 3.7383 5 yes
GO:0060271 cilium assembly 3.7383 6 yes
GO:0010596 negative regulation of endothelial cell migration 3.7383 6 yes
GO:0010611 regulation of cardiac muscle hypertrophy 3.7383 5 yes
GO:0010812 negative regulation of cell-substrate adhesion 3.7383 6 yes
GO:0070167 regulation of biomineral tissue development 3.7383 5 yes
GO:0014743 regulation of muscle hypertrophy 3.7383 6 yes
GO:0072091 regulation of stem cell proliferation 3.7383 5 yes
GO:0030178 negative regulation of Wnt signaling pathway 3.7383 6 yes
GO:0030278 regulation of ossification 3.7383 4 yes
GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3.7383 7 yes
GO:0090090 negative regulation of canonical Wnt signaling pathway 3.7383 7 yes
GO:0030510 regulation of BMP signaling pathway 3.7383 5 yes
GO:0030857 negative regulation of epithelial cell differentiation 3.7383 6 yes
GO:1901532 regulation of hematopoietic progenitor cell differentiation 3.7383 5 yes
GO:0032495 response to muramyl dipeptide 3.7383 4 yes
GO:0035914 skeletal muscle cell differentiation 3.7383 4 yes
GO:2000047 regulation of cell-cell adhesion mediated by cadherin 3.7383 6 yes
GO:0043502 regulation of muscle adaptation 3.7383 4 yes
GO:0044782 cilium organization 3.7383 5 yes
GO:0045601 regulation of endothelial cell differentiation 3.7383 6 yes
GO:0045667 regulation of osteoblast differentiation 3.7383 5 yes
GO:0045685 regulation of glial cell differentiation 3.7383 5 yes
GO:0045920 negative regulation of exocytosis 3.7383 6 yes
GO:0045995 regulation of embryonic development 3.7383 5 yes
GO:0046620 regulation of organ growth 3.7383 4 yes
GO:0002065 columnar/cuboidal epithelial cell differentiation 3.7383 5 yes
GO:0048708 astrocyte differentiation 3.7383 5 yes
GO:0048873 homeostasis of number of cells within a tissue 3.7383 4 yes
GO:0051153 regulation of striated muscle cell differentiation 3.7383 6 yes
GO:0060038 cardiac muscle cell proliferation 2.8037 5 yes
GO:0009913 epidermal cell differentiation 2.8037 5 yes
GO:0060563 neuroepithelial cell differentiation 2.8037 6 yes
GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 2.8037 6 yes
GO:0060973 cell migration involved in heart development 2.8037 4 yes
GO:0010718 positive regulation of epithelial to mesenchymal transition 2.8037 5 yes
GO:0061326 renal tubule development 2.8037 4 yes
GO:0014014 negative regulation of gliogenesis 2.8037 7 yes
GO:0070168 negative regulation of biomineral tissue development 2.8037 5 yes
GO:0014855 striated muscle cell proliferation 2.8037 4 yes
GO:0070986 left/right axis specification 2.8037 4 yes
GO:0071228 cellular response to tumor cell 2.8037 4 yes
GO:0021515 cell differentiation in spinal cord 2.8037 4 yes
GO:0021915 neural tube development 2.8037 4 yes
GO:0072009 nephron epithelium development 2.8037 6 yes
GO:0072073 kidney epithelium development 2.8037 5 yes
GO:0072080 nephron tubule development 2.8037 5 yes
GO:0072132 mesenchyme morphogenesis 2.8037 4 yes
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 2.8037 8 yes
GO:0030513 positive regulation of BMP signaling pathway 2.8037 6 yes
GO:0030514 negative regulation of BMP signaling pathway 2.8037 6 yes
GO:0097400 interleukin-17-mediated signaling pathway 2.8037 5 yes
GO:0030858 positive regulation of epithelial cell differentiation 2.8037 6 yes
GO:0120161 regulation of cold-induced thermogenesis 2.8037 4 yes
GO:1902692 regulation of neuroblast proliferation 2.8037 6 yes
GO:1903053 regulation of extracellular matrix organization 2.8037 5 yes
GO:1903306 negative regulation of regulated secretory pathway 2.8037 7 yes
GO:0035116 embryonic hindlimb morphogenesis 2.8037 6 yes
GO:0035137 hindlimb morphogenesis 2.8037 5 yes
GO:0035924 cellular response to vascular endothelial growth factor stimulus 2.8037 5 yes
GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2.8037 5 yes
GO:2000209 regulation of anoikis 2.8037 6 yes
GO:2000737 negative regulation of stem cell differentiation 2.8037 6 yes
GO:0043537 negative regulation of blood vessel endothelial cell migration 2.8037 7 yes
GO:2000811 negative regulation of anoikis 2.8037 7 yes
GO:0045055 regulated exocytosis 2.8037 4 yes
GO:0045603 positive regulation of endothelial cell differentiation 2.8037 7 yes
GO:0045604 regulation of epidermal cell differentiation 2.8037 5 yes
GO:0045616 regulation of keratinocyte differentiation 2.8037 6 yes
GO:0045668 negative regulation of osteoblast differentiation 2.8037 6 yes
GO:0045682 regulation of epidermis development 2.8037 4 yes
GO:0045686 negative regulation of glial cell differentiation 2.8037 6 yes
GO:0045687 positive regulation of glial cell differentiation 2.8037 6 yes
GO:0001570 vasculogenesis 2.8037 4 yes
GO:0046578 regulation of Ras protein signal transduction 2.8037 7 yes
GO:0046579 positive regulation of Ras protein signal transduction 2.8037 8 yes
GO:0046622 positive regulation of organ growth 2.8037 5 yes
GO:0048103 somatic stem cell division 2.8037 4 yes
GO:0048232 male gamete generation 2.8037 4 yes
GO:0002011 morphogenesis of an epithelial sheet 2.8037 5 yes
GO:0048514 blood vessel morphogenesis 2.8037 4 yes
GO:0002040 sprouting angiogenesis 2.8037 4 yes
GO:0002052 positive regulation of neuroblast proliferation 2.8037 7 yes
GO:0002064 epithelial cell development 2.8037 4 yes
GO:0048524 positive regulation of viral process 2.8037 4 yes
GO:0002067 glandular epithelial cell differentiation 2.8037 6 yes
GO:0003162 atrioventricular node development 2.8037 7 yes
GO:0048709 oligodendrocyte differentiation 2.8037 5 yes
GO:0003180 aortic valve morphogenesis 2.8037 4 yes
GO:0003181 atrioventricular valve morphogenesis 2.8037 4 yes
GO:0048713 regulation of oligodendrocyte differentiation 2.8037 6 yes
GO:0048715 negative regulation of oligodendrocyte differentiation 2.8037 7 yes
GO:0003184 pulmonary valve morphogenesis 2.8037 4 yes
GO:0003203 endocardial cushion morphogenesis 2.8037 5 yes
GO:0048863 stem cell differentiation 2.8037 4 yes
GO:0050922 negative regulation of chemotaxis 2.8037 5 yes
GO:0051150 regulation of smooth muscle cell differentiation 2.8037 6 yes
GO:0051152 positive regulation of smooth muscle cell differentiation 2.8037 7 yes
GO:0007221 positive regulation of transcription of Notch receptor target 1.8692 10 yes
GO:0007368 determination of left/right symmetry 1.8692 5 yes
GO:0007386 compartment pattern specification 1.8692 5 yes
GO:0007492 endoderm development 1.8692 4 yes
GO:0055001 muscle cell development 1.8692 4 yes
GO:0055006 cardiac cell development 1.8692 4 yes
GO:0055008 cardiac muscle tissue morphogenesis 1.8692 5 yes
GO:0009855 determination of bilateral symmetry 1.8692 4 yes
GO:0055010 ventricular cardiac muscle tissue morphogenesis 1.8692 6 yes
GO:0055021 regulation of cardiac muscle tissue growth 1.8692 6 yes
GO:0055023 positive regulation of cardiac muscle tissue growth 1.8692 7 yes
GO:0060043 regulation of cardiac muscle cell proliferation 1.8692 5 yes
GO:0060045 positive regulation of cardiac muscle cell proliferation 1.8692 6 yes
GO:0009912 auditory receptor cell fate commitment 1.8692 6 yes
GO:0060120 inner ear receptor cell fate commitment 1.8692 5 yes
GO:0060219 camera-type eye photoreceptor cell differentiation 1.8692 7 yes
GO:0009957 epidermal cell fate specification 1.8692 4 yes
GO:0060253 negative regulation of glial cell proliferation 1.8692 6 yes
GO:0060317 cardiac epithelial to mesenchymal transition 1.8692 6 yes
GO:0010002 cardioblast differentiation 1.8692 5 yes
GO:0060353 regulation of cell adhesion molecule production 1.8692 4 yes
GO:0060354 negative regulation of cell adhesion molecule production 1.8692 5 yes
GO:0060379 cardiac muscle cell myoblast differentiation 1.8692 5 yes
GO:0060412 ventricular septum morphogenesis 1.8692 4 yes
GO:0060415 muscle tissue morphogenesis 1.8692 4 yes
GO:0060420 regulation of heart growth 1.8692 5 yes
GO:0060421 positive regulation of heart growth 1.8692 6 yes
GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development 1.8692 4 yes
GO:0060561 apoptotic process involved in morphogenesis 1.8692 6 yes
GO:0010614 negative regulation of cardiac muscle hypertrophy 1.8692 6 yes
GO:0060837 blood vessel endothelial cell differentiation 1.8692 6 yes
GO:0060842 arterial endothelial cell differentiation 1.8692 7 yes
GO:0060843 venous endothelial cell differentiation 1.8692 7 yes
GO:0010712 regulation of collagen metabolic process 1.8692 4 yes
GO:0060948 cardiac vascular smooth muscle cell development 1.8692 5 yes
GO:0010713 negative regulation of collagen metabolic process 1.8692 5 yes
GO:0060956 endocardial cell differentiation 1.8692 6 yes
GO:0060977 coronary vasculature morphogenesis 1.8692 5 yes
GO:0060979 vasculogenesis involved in coronary vascular morphogenesis 1.8692 5 yes
GO:0060982 coronary artery morphogenesis 1.8692 6 yes
GO:0061101 neuroendocrine cell differentiation 1.8692 5 yes
GO:0061311 cell surface receptor signaling pathway involved in heart development 1.8692 4 yes
GO:0010830 regulation of myotube differentiation 1.8692 7 yes
GO:0061314 Notch signaling involved in heart development 1.8692 5 yes
GO:0010832 negative regulation of myotube differentiation 1.8692 8 yes
GO:0061344 regulation of cell adhesion involved in heart morphogenesis 1.8692 5 yes
GO:0061384 heart trabecula morphogenesis 1.8692 4 yes
GO:0062042 regulation of cardiac epithelial to mesenchymal transition 1.8692 6 yes
GO:0014031 mesenchymal cell development 1.8692 4 yes
GO:0062043 positive regulation of cardiac epithelial to mesenchymal transition 1.8692 6 yes
GO:0014741 negative regulation of muscle hypertrophy 1.8692 5 yes
GO:0014807 regulation of somitogenesis 1.8692 4 yes
GO:0017156 calcium-ion regulated exocytosis 1.8692 5 yes
GO:0017158 regulation of calcium ion-dependent exocytosis 1.8692 7 yes
GO:0071371 cellular response to gonadotropin stimulus 1.8692 5 yes
GO:0071372 cellular response to follicle-stimulating hormone stimulus 1.8692 6 yes
GO:0072017 distal tubule development 1.8692 6 yes
GO:0072044 collecting duct development 1.8692 4 yes
GO:0072143 mesangial cell development 1.8692 4 yes
GO:0072144 glomerular mesangial cell development 1.8692 5 yes
GO:0072148 epithelial cell fate commitment 1.8692 4 yes
GO:0072538 T-helper 17 type immune response 1.8692 5 yes
GO:0030216 keratinocyte differentiation 1.8692 6 yes
GO:0030279 negative regulation of ossification 1.8692 5 yes
GO:0030324 lung development 1.8692 4 yes
GO:0097084 vascular associated smooth muscle cell development 1.8692 5 yes
GO:0031100 animal organ regeneration 1.8692 4 yes
GO:0120163 negative regulation of cold-induced thermogenesis 1.8692 5 yes
GO:1901201 regulation of extracellular matrix assembly 1.8692 5 yes
GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1.8692 6 yes
GO:1902263 apoptotic process involved in embryonic digit morphogenesis 1.8692 7 yes
GO:0032354 response to follicle-stimulating hormone 1.8692 5 yes
GO:1902337 regulation of apoptotic process involved in morphogenesis 1.8692 5 yes
GO:1902339 positive regulation of apoptotic process involved in morphogenesis 1.8692 6 yes
GO:0032965 regulation of collagen biosynthetic process 1.8692 5 yes
GO:0032966 negative regulation of collagen biosynthetic process 1.8692 6 yes
GO:1902742 apoptotic process involved in development 1.8692 5 yes
GO:1903054 negative regulation of extracellular matrix organization 1.8692 6 yes
GO:0034698 response to gonadotropin 1.8692 4 yes
GO:0035051 cardiocyte differentiation 1.8692 4 yes
GO:1903847 regulation of aorta morphogenesis 1.8692 6 yes
GO:1903849 positive regulation of aorta morphogenesis 1.8692 6 yes
GO:1903900 regulation of viral life cycle 1.8692 4 yes
GO:1904747 positive regulation of apoptotic process involved in development 1.8692 5 yes
GO:1904748 regulation of apoptotic process involved in development 1.8692 4 yes
GO:1904894 positive regulation of receptor signaling pathway via STAT 1.8692 6 yes
GO:1905456 regulation of lymphoid progenitor cell differentiation 1.8692 6 yes
GO:1905457 negative regulation of lymphoid progenitor cell differentiation 1.8692 7 yes
GO:0040034 regulation of development, heterochronic 1.8692 4 yes
GO:1905651 regulation of artery morphogenesis 1.8692 5 yes
GO:1905653 positive regulation of artery morphogenesis 1.8692 5 yes
GO:0042670 retinal cone cell differentiation 1.8692 8 yes
GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin 1.8692 7 yes
GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis 1.8692 6 yes
GO:2000973 regulation of pro-B cell differentiation 1.8692 7 yes
GO:2000974 negative regulation of pro-B cell differentiation 1.8692 8 yes
GO:2000980 regulation of inner ear receptor cell differentiation 1.8692 7 yes
GO:2000981 negative regulation of inner ear receptor cell differentiation 1.8692 8 yes
GO:0045069 regulation of viral genome replication 1.8692 5 yes
GO:2001026 regulation of endothelial cell chemotaxis 1.8692 5 yes
GO:0045070 positive regulation of viral genome replication 1.8692 5 yes
GO:2001027 negative regulation of endothelial cell chemotaxis 1.8692 6 yes
GO:0045446 endothelial cell differentiation 1.8692 5 yes
GO:0045605 negative regulation of epidermal cell differentiation 1.8692 6 yes
GO:0045606 positive regulation of epidermal cell differentiation 1.8692 6 yes
GO:0045607 regulation of inner ear auditory receptor cell differentiation 1.8692 6 yes
GO:0045608 negative regulation of inner ear auditory receptor cell differentiation 1.8692 7 yes
GO:0045618 positive regulation of keratinocyte differentiation 1.8692 5 yes
GO:0045631 regulation of mechanoreceptor differentiation 1.8692 6 yes
GO:0045632 negative regulation of mechanoreceptor differentiation 1.8692 7 yes
GO:0045661 regulation of myoblast differentiation 1.8692 5 yes
GO:0045662 negative regulation of myoblast differentiation 1.8692 6 yes
GO:0045683 negative regulation of epidermis development 1.8692 5 yes
GO:0045684 positive regulation of epidermis development 1.8692 5 yes
GO:0045747 positive regulation of Notch signaling pathway 1.8692 6 yes
GO:0045955 negative regulation of calcium ion-dependent exocytosis 1.8692 8 yes
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1.8692 7 yes
GO:0046530 photoreceptor cell differentiation 1.8692 5 yes
GO:0046532 regulation of photoreceptor cell differentiation 1.8692 6 yes
GO:0046533 negative regulation of photoreceptor cell differentiation 1.8692 5 yes
GO:0001754 eye photoreceptor cell differentiation 1.8692 6 yes
GO:0048505 regulation of timing of cell differentiation 1.8692 5 yes
GO:0002085 inhibition of neuroepithelial cell differentiation 1.8692 5 yes
GO:0048663 neuron fate commitment 1.8692 4 yes
GO:0003169 coronary vein morphogenesis 1.8692 6 yes
GO:0048710 regulation of astrocyte differentiation 1.8692 6 yes
GO:0048711 positive regulation of astrocyte differentiation 1.8692 7 yes
GO:0003182 coronary sinus valve morphogenesis 1.8692 4 yes
GO:0003190 atrioventricular valve formation 1.8692 4 yes
GO:0003192 mitral valve formation 1.8692 5 yes
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1.8692 7 yes
GO:0048844 artery morphogenesis 1.8692 5 yes
GO:0003208 cardiac ventricle morphogenesis 1.8692 4 yes
GO:0048845 venous blood vessel morphogenesis 1.8692 5 yes
GO:0003209 cardiac atrium morphogenesis 1.8692 4 yes
GO:0003211 cardiac ventricle formation 1.8692 4 yes
GO:0003213 cardiac right atrium morphogenesis 1.8692 5 yes
GO:0003214 cardiac left ventricle morphogenesis 1.8692 5 yes
GO:0003219 cardiac right ventricle formation 1.8692 5 yes
GO:0050680 negative regulation of epithelial cell proliferation 1.8692 6 yes
GO:0003222 ventricular trabecula myocardium morphogenesis 1.8692 5 yes
GO:0003241 growth involved in heart morphogenesis 1.8692 4 yes
GO:0003250 regulation of cell proliferation involved in heart valve morphogenesis 1.8692 6 yes
GO:0003252 negative regulation of cell proliferation involved in heart valve morphogenesis 1.8692 7 yes
GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1.8692 6 yes
GO:0003273 cell migration involved in endocardial cushion formation 1.8692 5 yes
GO:0003330 regulation of extracellular matrix constituent secretion 1.8692 5 yes
GO:0003332 negative regulation of extracellular matrix constituent secretion 1.8692 6 yes
GO:0003344 pericardium morphogenesis 1.8692 4 yes
GO:0003348 cardiac endothelial cell differentiation 1.8692 5 yes
GO:0051148 negative regulation of muscle cell differentiation 1.8692 6 yes
GO:0051154 negative regulation of striated muscle cell differentiation 1.8692 7 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
IMB1_HUMAN [view entry] [view interactions] Low throughput yes yes
DLL1_HUMAN [view interactions] Low throughput no no
DLL4_HUMAN [view interactions] Low throughput no no
HIF1N_HUMAN [view interactions] Low throughput no yes
KAT2B_HUMAN [view interactions] Low throughput no yes
KAT2A_HUMAN [view interactions] Low throughput no no
EP300_HUMAN [view interactions] Low throughput no yes
EGFL7_HUMAN [view interactions] Low throughput no yes
AKT1_HUMAN [view entry] [view interactions] Low throughput yes yes
LCK_HUMAN [view entry] [view interactions] Low throughput yes no
PK3CA_HUMAN [view entry] [view interactions] Low throughput yes yes
CNTN1_HUMAN [view entry] [view interactions] Low throughput yes yes
TYY1_HUMAN [view interactions] Low throughput no yes
DTX1_HUMAN [view interactions] Low throughput no yes
TF65_HUMAN [view entry] [view interactions] Low throughput yes yes
CCN3_HUMAN [view interactions] Low throughput no no
CBL_HUMAN [view interactions] Low throughput no yes
SNAI1_HUMAN [view interactions] Low throughput no yes
MDM2_HUMAN [view entry] [view interactions] Low throughput yes yes
NUMB_HUMAN [view entry] [view interactions] Low throughput yes yes
RUNX3_HUMAN [view interactions] Low throughput no no
KAT5_HUMAN [view interactions] Low throughput no yes
A4_HUMAN [view entry] [view interactions] Low throughput yes yes
APBB1_HUMAN [view entry] [view interactions] Low throughput yes yes
EPN1_HUMAN [view entry] [view interactions] Low throughput yes yes
KCC4_HUMAN [view entry] [view interactions] Low throughput yes yes
NED4L_HUMAN [view entry] [view interactions] Low throughput yes yes
ARRB1_HUMAN [view entry] [view interactions] Low throughput yes yes
TGFR1_HUMAN [view interactions] Low throughput no no
RND3_HUMAN [view interactions] Low throughput no no
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB5A_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB7A_HUMAN [view entry] [view interactions] Low throughput yes yes
LAMP1_HUMAN [view entry] [view interactions] Low throughput yes yes
HGS_HUMAN [view entry] [view interactions] Low throughput yes yes
ZMIZ1_HUMAN [view interactions] Low throughput no no
MLP3A_HUMAN [view entry] [view interactions] Low throughput yes yes
SQSTM_HUMAN [view interactions] Low throughput no yes
M3K1_HUMAN [view interactions] Low throughput no yes
HS90B_HUMAN [view entry] [view interactions] Low throughput yes yes
CHIP_HUMAN [view entry] [view interactions] Low throughput yes yes
MAGA1_HUMAN [view interactions] Low throughput no no
BACD3_HUMAN [view interactions] Low throughput no yes
CUL3_HUMAN [view entry] [view interactions] Low throughput yes yes
DTX4_HUMAN [view interactions] Low throughput no yes
TRIM3_HUMAN [view entry] [view interactions] Low throughput yes no
CASR_HUMAN [view interactions] Low throughput no no
M3K7_HUMAN [view interactions] Low throughput no yes
TRAF6_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP10_HUMAN [view interactions] Low throughput no yes
TRBP2_HUMAN [view interactions] Low throughput no yes
DAB1_HUMAN [view interactions] Low throughput no yes
F16P1_HUMAN [view interactions] Low throughput no no
STC1_HUMAN [view entry] [view interactions] Low throughput yes no
UBP8_HUMAN [view entry] [view interactions] Low throughput yes no
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP18_HUMAN [view interactions] Low throughput no yes
DDR1_HUMAN [view interactions] Low throughput no yes
SNW1_HUMAN [view interactions] Low throughput no yes
SUH_HUMAN [view interactions] Low throughput no yes
MAML2_HUMAN [view interactions] Low throughput no yes
MAML1_HUMAN [view interactions] Low throughput no yes
MAML3_HUMAN [view interactions] Low throughput no yes
REL_HUMAN [view interactions] Low throughput no yes
NFKB1_HUMAN [view interactions] Low throughput no yes
XIAP_HUMAN [view interactions] Low throughput no yes
KDM1A_HUMAN [view interactions] Low throughput no yes
SMCA4_HUMAN [view interactions] Low throughput no yes
UBP7_HUMAN [view interactions] Low throughput no yes
SMRD3_HUMAN [view interactions] Low throughput no no
FBXW7_HUMAN [view interactions] Low throughput no yes
EIF3F_HUMAN [view interactions] Low throughput no yes
ATM_HUMAN [view interactions] Low throughput no yes
NOTC1_HUMAN [view entry] [view interactions] Low throughput yes yes
PIN1_HUMAN [view entry] [view interactions] Low throughput yes yes
SMAD3_HUMAN [view interactions] Low throughput no yes
JAG1_HUMAN [view interactions] Low throughput no no
UBB_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
RS27A_HUMAN [view entry] [view interactions] Low throughput yes yes
RL40_HUMAN [view entry] [view interactions] Low throughput yes yes
ITCH_HUMAN [view interactions] Low throughput no yes
LIRB2_HUMAN [view interactions] Low throughput no no
HIF1A_HUMAN [view interactions] Low throughput no no
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
NLK_HUMAN [view interactions] Low throughput no yes
SIAH1_HUMAN [view interactions] Low throughput no yes
RHBL2_HUMAN [view interactions] Low throughput no yes
OTU7B_HUMAN [view interactions] Low throughput no yes
HEY1_HUMAN [view interactions] Low throughput no yes
HEY2_HUMAN [view interactions] Low throughput no no
RCOR2_HUMAN [view interactions] Low throughput no no
WDR12_HUMAN [view interactions] Low throughput no yes
JAG2_HUMAN [view interactions] Low throughput no yes
LEF1_HUMAN [view interactions] Low throughput no no
GSK3B_HUMAN [view entry] [view interactions] Low throughput yes yes
WWP1_HUMAN [view interactions] Low throughput no yes
ILK_HUMAN [view interactions] Low throughput no no
GRAB_HUMAN [view interactions] Low throughput no no
PSN1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP12_HUMAN [view interactions] Low throughput no yes
UBP2_HUMAN [view interactions] Low throughput no yes
NOTC3_HUMAN [view interactions] Low throughput no yes
ADA10_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB4A_HUMAN [view entry] [view interactions] Low throughput yes no
TAF1_HUMAN [view interactions] Low throughput no yes
STK38_HUMAN [view entry] [view interactions] Low throughput yes yes
OFUT1_HUMAN [view interactions] Low throughput no yes
PGLT1_HUMAN [view interactions] Low throughput no no
APH1A_HUMAN [view interactions] Low throughput no yes
NICA_HUMAN [view interactions] Low throughput no yes
PEN2_HUMAN [view interactions] Low throughput no yes
NRARP_HUMAN [view interactions] Low throughput no no
PTBP1_HUMAN [view interactions] High throughput no no
CNOT1_HUMAN [view interactions] High throughput no yes
XPO5_HUMAN [view interactions] High throughput no yes
NBEA_HUMAN [view entry] [view interactions] High throughput yes yes
LRBA_HUMAN [view interactions] High throughput no yes
MDN1_HUMAN [view interactions] High throughput no no
TNPO1_HUMAN [view entry] [view interactions] High throughput yes yes
IPO5_HUMAN [view entry] [view interactions] High throughput yes yes
TPPC9_HUMAN [view entry] [view interactions] High throughput yes no
TPC10_HUMAN [view interactions] High throughput no no
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
VPS39_HUMAN [view entry] [view interactions] High throughput yes no
VPS11_HUMAN [view entry] [view interactions] High throughput yes no
KIF3A_HUMAN [view entry] [view interactions] High throughput yes yes
KIF2A_HUMAN [view entry] [view interactions] High throughput yes yes
LATS2_HUMAN [view interactions] High throughput no yes
TMM17_HUMAN [view interactions] High throughput no yes
RASK_HUMAN [view entry] [view interactions] High throughput yes no
RASN_HUMAN [view entry] [view interactions] High throughput yes no
RASH_HUMAN [view entry] [view interactions] High throughput yes no
KCNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
CTDSL_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
KCNK3_HUMAN [view interactions] High throughput no no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
PP2AB_HUMAN [view interactions] High throughput no yes
PSN2_HUMAN [view entry] [view interactions] High throughput yes no
ANR44_HUMAN [view interactions] High throughput no no
DLK2_HUMAN [view interactions] High throughput no no
FANCA_HUMAN [view interactions] High throughput no no
FANCC_HUMAN [view interactions] High throughput no yes
FANCF_HUMAN [view interactions] High throughput no no
FANCG_HUMAN [view interactions] High throughput no yes
TRI25_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
SENP7_HUMAN [view entry] [view interactions] High throughput yes yes
MKRN2_HUMAN [view interactions] High throughput no yes
IGSF5_HUMAN [view interactions] High throughput no no
MARH1_HUMAN [view interactions] High throughput no yes
INAR1_HUMAN [view interactions] High throughput no yes
IGFL3_HUMAN [view interactions] High throughput no no
ABTB2_HUMAN [view interactions] High throughput no yes
VATD_HUMAN [view entry] [view interactions] High throughput yes yes
MYPT2_HUMAN [view interactions] High throughput no no
GFI1B_HUMAN [view interactions] High throughput no no
LEG1_HUMAN [view interactions] High throughput no yes
CAC1A_HUMAN [view entry] [view interactions] High throughput yes no
NET5_HUMAN [view interactions] High throughput no no
VEGFD_HUMAN [view interactions] High throughput no no
WNT2_HUMAN [view interactions] High throughput no no
ZN707_HUMAN [view interactions] High throughput no yes
EDN3_HUMAN [view interactions] High throughput no no
HGF_HUMAN [view interactions] High throughput no yes
ZDH12_HUMAN [view interactions] High throughput no yes
CST9L_HUMAN [view interactions] High throughput no no
PHF8_HUMAN [view interactions] High throughput no yes
WNT3A_HUMAN [view entry] [view interactions] High throughput yes no
FRYL_HUMAN [view entry] [view interactions] High throughput yes yes
ESPB1_HUMAN [view interactions] High throughput no no
CCN6_HUMAN [view interactions] High throughput no no
PB1_HUMAN [view interactions] High throughput no yes
CLC2B_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
SIRPD_HUMAN [view interactions] High throughput no no
2ABA_HUMAN [view interactions] High throughput no yes
IBP4_HUMAN [view interactions] High throughput no no
WN10A_HUMAN [view interactions] High throughput no no
MK01_HUMAN [view entry] [view interactions] High throughput yes yes
CI163_HUMAN [view interactions] High throughput no no
BC11B_HUMAN [view interactions] High throughput no yes
DKK2_HUMAN [view interactions] High throughput no no
RBBP4_HUMAN [view interactions] High throughput no yes
LPAR2_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
ZNF74_HUMAN [view interactions] High throughput no yes
PRKDC_HUMAN [view entry] [view interactions] High throughput yes yes
CFC1_HUMAN [view interactions] High throughput no no
TOP2B_HUMAN [view interactions] High throughput no yes
FBX2_HUMAN [view entry] [view interactions] High throughput yes yes
FX4L6_HUMAN [view interactions] High throughput no no
PRG2_HUMAN [view interactions] High throughput no no
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
RHOJ_HUMAN [view interactions] High throughput no yes
RHOQ_HUMAN [view interactions] High throughput no no
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
RAC3_HUMAN [view entry] [view interactions] High throughput yes no
RHOG_HUMAN [view entry] [view interactions] High throughput yes no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
RHOD_HUMAN [view interactions] High throughput no no
RHOF_HUMAN [view interactions] High throughput no no
RHOU_HUMAN [view interactions] High throughput no no
RND1_HUMAN [view interactions] High throughput no no
RND2_HUMAN [view interactions] High throughput no no
RHOC_HUMAN [view interactions] High throughput no no
RHOV_HUMAN [view interactions] High throughput no no
XRCC6_HUMAN [view interactions] High throughput no yes
RHOH_HUMAN [view interactions] High throughput no yes
HXA1_HUMAN [view interactions] High throughput no no
MBD1_HUMAN [view interactions] High throughput no yes
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
PRAF3_HUMAN [view interactions] High throughput no yes
CLD4_HUMAN [view interactions] High throughput no yes
B3GT4_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
CE57L_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
CO4A6_HUMAN [view interactions] High throughput no no
EXT1_HUMAN [view interactions] High throughput no yes
F185A_HUMAN [view interactions] High throughput no no
P33MX_HUMAN [view interactions] High throughput no yes
LNX2_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
GOGA2_HUMAN [view entry] [view interactions] High throughput yes yes
HMGN5_HUMAN [view interactions] High throughput no no
MAGD1_HUMAN [view interactions] High throughput no no
GOPC_HUMAN [view entry] [view interactions] High throughput yes yes
OBF1_HUMAN [view interactions] High throughput no no
TLE3_HUMAN [view interactions] High throughput no yes
DAZP2_HUMAN [view interactions] High throughput no no
NOTC2_HUMAN [view entry] [view interactions] High throughput yes yes
AAPK1_HUMAN [view interactions] High throughput no no
LIMK2_HUMAN [view interactions] High throughput no yes
ROCK1_HUMAN [view entry] [view interactions] High throughput yes yes
CADH1_HUMAN [view entry] [view interactions] High throughput yes no
TAB1_HUMAN [view interactions] High throughput no yes
SC61B_HUMAN [view interactions] High throughput no yes
MOB1A_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
HCLS1_HUMAN [view interactions] High throughput no no
ARF6_HUMAN [view entry] [view interactions] High throughput yes yes
RANB9_HUMAN [view entry] [view interactions] High throughput yes yes
CK052_HUMAN [view interactions] High throughput no no
RBP10_HUMAN [view interactions] High throughput no no
CAV1_HUMAN [view interactions] High throughput no no
VAV_HUMAN [view interactions] High throughput no no
DIRA3_HUMAN [view interactions] High throughput no yes
ARHG2_HUMAN [view entry] [view interactions] High throughput yes yes
ELOV5_HUMAN [view interactions] High throughput no yes
UBP11_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
CXD3_HUMAN [view interactions] High throughput no no
PP6R1_HUMAN [view interactions] High throughput no no
LTOR1_HUMAN [view entry] [view interactions] High throughput yes yes
PP6R3_HUMAN [view interactions] High throughput no yes
LYN_HUMAN [view entry] [view interactions] High throughput yes no
ARI1_HUMAN [view interactions] High throughput no yes
MARCS_HUMAN [view entry] [view interactions] High throughput yes yes
ARI2_HUMAN [view interactions] High throughput no no
OCLN_HUMAN [view interactions] High throughput no no
TRI32_HUMAN [view entry] [view interactions] High throughput yes yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
APC7_HUMAN [view interactions] High throughput no yes
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
APC1_HUMAN [view interactions] High throughput no no
RAB35_HUMAN [view entry] [view interactions] High throughput yes yes
CDC23_HUMAN [view interactions] High throughput no yes
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
CDC27_HUMAN [view interactions] High throughput no yes
STX4_HUMAN [view entry] [view interactions] High throughput yes no
APC5_HUMAN [view interactions] High throughput no yes
STX6_HUMAN [view interactions] High throughput no yes
STX7_HUMAN [view entry] [view interactions] High throughput yes yes
CSN1_HUMAN [view interactions] High throughput no no
ZFPL1_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
DTX2_HUMAN [view interactions] High throughput no yes
SLFN5_HUMAN [view interactions] High throughput no yes
TGON2_HUMAN [view entry] [view interactions] High throughput yes yes
SLN11_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
CARL2_HUMAN [view interactions] High throughput no yes
LRCH1_HUMAN [view interactions] High throughput no yes
WDR11_HUMAN [view interactions] High throughput no yes
NCKPL_HUMAN [view entry] [view interactions] High throughput yes yes
ARMC8_HUMAN [view interactions] High throughput no yes
ERH_HUMAN [view interactions] High throughput no yes
WDR6_HUMAN [view entry] [view interactions] High throughput yes yes
RMC1_HUMAN [view interactions] High throughput no no
PTBP3_HUMAN [view interactions] High throughput no no
CCZ1B_HUMAN [view interactions] High throughput no yes
CCZ1_HUMAN [view interactions] High throughput no yes
SMRC2_HUMAN [view interactions] High throughput no yes
SMRC1_HUMAN [view interactions] High throughput no yes
HLTF_HUMAN [view interactions] High throughput no no
SMCA5_HUMAN [view interactions] High throughput no yes
SMC1A_HUMAN [view interactions] High throughput no yes
SMC3_HUMAN [view entry] [view interactions] High throughput yes yes
PDS5A_HUMAN [view interactions] High throughput no yes
SCC4_HUMAN [view interactions] High throughput no no
SMHD1_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
WIZ_HUMAN [view interactions] High throughput no yes
RB_HUMAN [view interactions] High throughput no yes
BRE1B_HUMAN [view interactions] High throughput no yes
CHD4_HUMAN [view interactions] High throughput no yes
P66B_HUMAN [view interactions] High throughput no yes
RING1_HUMAN [view interactions] High throughput no yes
RING2_HUMAN [view interactions] High throughput no yes
HCFC1_HUMAN [view interactions] High throughput no yes
RTRAF_HUMAN [view interactions] High throughput no yes
ASCC3_HUMAN [view interactions] High throughput no yes
SRRT_HUMAN [view interactions] High throughput no yes
TBL1R_HUMAN [view interactions] High throughput no yes
WWTR1_HUMAN [view interactions] High throughput no yes
DDX17_HUMAN [view entry] [view interactions] High throughput yes yes
HTSF1_HUMAN [view interactions] High throughput no yes
MED23_HUMAN [view interactions] High throughput no no
MED25_HUMAN [view interactions] High throughput no yes
IKZF1_HUMAN [view interactions] High throughput no no
IKZF2_HUMAN [view interactions] High throughput no no
IKZF3_HUMAN [view interactions] High throughput no no
HTF4_HUMAN [view interactions] High throughput no yes
RUNX1_HUMAN [view interactions] High throughput no yes
SMAD9_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
ZBED4_HUMAN [view interactions] High throughput no yes
RFX1_HUMAN [view interactions] High throughput no yes
IF16_HUMAN [view interactions] High throughput no no
PARP1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM3_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
RFC1_HUMAN [view interactions] High throughput no yes
RFC4_HUMAN [view interactions] High throughput no yes
MMS19_HUMAN [view interactions] High throughput no yes
RIF1_HUMAN [view interactions] High throughput no yes
PRP6_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
PRP19_HUMAN [view interactions] High throughput no yes
RBM10_HUMAN [view interactions] High throughput no yes
DHX15_HUMAN [view interactions] High throughput no yes
DHX8_HUMAN [view interactions] High throughput no yes
SNUT1_HUMAN [view interactions] High throughput no yes