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ARHG2_HUMAN

Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases, which was uniquely reported in PubMed. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras-GTPases. Forms an intracellular sensing system along with NOD1 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIP2 dependent NF-kappaB signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides through NOD1 that is independent of its GEF activity, but also in the activation of NF-kappaB by Shigella effector proteins (IpgB2 and OspB) which requires its GEF activity and the activation of RhoA. Involved in innate immune signaling transduction pathway promoting cytokine IL6/interleukin-6 and TNF-alpha secretion in macrophage upon stimulation by bacterial peptidoglycans; acts as a signaling intermediate between NOD2 receptor and RIPK2 kinase. Contributes to the tyrosine phosphorylation of RIPK2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2. Overexpression activates Rho-, but not Rac-GTPases, and increases paracellular permeability . Involved in neuronal progenitor cell division and differentiation (PubMed). Involved in the migration of precerebellar neurons . [View more on UniProt]

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ELM instance Name Type Start End Partner
ELMI003167 DOC_PP2A_B56_1 DOC 967 972 -
ELMI003167 DOC_PP2A_B56_1 DOC 967 972 -

Molecular function

Term Name % Distance from the top of the tree Annotated in ARHG2_HUMAN
GO:0043168 anion binding 23.9583 4 no
GO:0019900 kinase binding 23.9583 4 no
GO:0019901 protein kinase binding 22.9167 5 no
GO:0000166 nucleotide binding 21.8750 4 no
GO:0017076 purine nucleotide binding 21.8750 5 no
GO:0032555 purine ribonucleotide binding 21.8750 4 no
GO:0035639 purine ribonucleoside triphosphate binding 21.8750 4 no
GO:0043169 cation binding 19.7917 4 yes
GO:0046872 metal ion binding 19.7917 5 yes
GO:0015631 tubulin binding 12.5000 4 yes
GO:0030695 GTPase regulator activity 12.5000 4 yes
GO:0051020 GTPase binding 12.5000 4 yes
GO:0031267 small GTPase binding 10.4167 5 yes
GO:0008017 microtubule binding 9.3750 5 yes
GO:0005085 guanyl-nucleotide exchange factor activity 7.2917 5 yes
GO:0008270 zinc ion binding 7.2917 7 yes
GO:0046914 transition metal ion binding 7.2917 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ARHG2_HUMAN
GO:0048522 positive regulation of cellular process 57.2917 4 yes
GO:0048523 negative regulation of cellular process 56.2500 4 yes
GO:0060255 regulation of macromolecule metabolic process 55.2083 4 yes
GO:0031323 regulation of cellular metabolic process 55.2083 4 yes
GO:0051128 regulation of cellular component organization 55.2083 4 yes
GO:0080090 regulation of primary metabolic process 54.1667 4 yes
GO:0010646 regulation of cell communication 53.1250 4 yes
GO:0006996 organelle organization 44.7917 4 no
GO:0009889 regulation of biosynthetic process 44.7917 4 yes
GO:0009966 regulation of signal transduction 44.7917 4 yes
GO:0031326 regulation of cellular biosynthetic process 43.7500 5 yes
GO:0010556 regulation of macromolecule biosynthetic process 42.7083 5 yes
GO:0022607 cellular component assembly 40.6250 4 no
GO:0009893 positive regulation of metabolic process 39.5833 4 yes
GO:0010468 regulation of gene expression 39.5833 6 yes
GO:0051246 regulation of protein metabolic process 38.5417 5 yes
GO:0010604 positive regulation of macromolecule metabolic process 38.5417 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 36.4583 5 yes
GO:0030030 cell projection organization 35.4167 4 no
GO:0008104 protein localization 35.4167 4 yes
GO:0031325 positive regulation of cellular metabolic process 35.4167 5 yes
GO:0031399 regulation of protein modification process 35.4167 6 yes
GO:0009892 negative regulation of metabolic process 34.3750 4 no
GO:0051252 regulation of RNA metabolic process 33.3333 5 yes
GO:1902531 regulation of intracellular signal transduction 33.3333 5 yes
GO:0051174 regulation of phosphorus metabolic process 31.2500 5 yes
GO:0010605 negative regulation of macromolecule metabolic process 31.2500 5 no
GO:0019220 regulation of phosphate metabolic process 31.2500 6 yes
GO:2001141 regulation of RNA biosynthetic process 30.2083 6 yes
GO:0036211 protein modification process 30.2083 4 no
GO:0043412 macromolecule modification 30.2083 4 no
GO:0006355 regulation of DNA-templated transcription 30.2083 7 yes
GO:0051247 positive regulation of protein metabolic process 29.1667 6 yes
GO:0044087 regulation of cellular component biogenesis 29.1667 4 no
GO:0031324 negative regulation of cellular metabolic process 29.1667 5 no
GO:0051130 positive regulation of cellular component organization 28.1250 5 no
GO:0048585 negative regulation of response to stimulus 28.1250 4 yes
GO:0120036 plasma membrane bounded cell projection organization 27.0833 5 no
GO:0042325 regulation of phosphorylation 27.0833 7 yes
GO:0048584 positive regulation of response to stimulus 26.0417 4 no
GO:0001932 regulation of protein phosphorylation 26.0417 7 yes
GO:0031401 positive regulation of protein modification process 26.0417 7 yes
GO:0033043 regulation of organelle organization 26.0417 5 yes
GO:0051493 regulation of cytoskeleton organization 25.0000 6 yes
GO:0031344 regulation of cell projection organization 25.0000 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 25.0000 6 no
GO:0007010 cytoskeleton organization 25.0000 5 no
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0010648 negative regulation of cell communication 25.0000 5 yes
GO:0023057 negative regulation of signaling 25.0000 4 yes
GO:0042981 regulation of apoptotic process 25.0000 5 yes
GO:0043067 regulation of programmed cell death 25.0000 4 yes
GO:0045595 regulation of cell differentiation 25.0000 4 yes
GO:0022603 regulation of anatomical structure morphogenesis 23.9583 4 no
GO:0006796 phosphate-containing compound metabolic process 23.9583 4 no
GO:0009891 positive regulation of biosynthetic process 23.9583 5 yes
GO:0009968 negative regulation of signal transduction 23.9583 5 yes
GO:0141124 intracellular signaling cassette 22.9167 4 no
GO:0010562 positive regulation of phosphorus metabolic process 22.9167 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 22.9167 6 yes
GO:0045937 positive regulation of phosphate metabolic process 22.9167 7 yes
GO:0071702 organic substance transport 21.8750 4 yes
GO:0009967 positive regulation of signal transduction 21.8750 5 no
GO:0009890 negative regulation of biosynthetic process 21.8750 5 no
GO:0051049 regulation of transport 21.8750 4 no
GO:0010557 positive regulation of macromolecule biosynthetic process 21.8750 6 yes
GO:1902903 regulation of supramolecular fiber organization 20.8333 5 yes
GO:2000145 regulation of cell motility 20.8333 4 yes
GO:0010558 negative regulation of macromolecule biosynthetic process 20.8333 6 no
GO:0031327 negative regulation of cellular biosynthetic process 20.8333 6 no
GO:0042327 positive regulation of phosphorylation 20.8333 8 yes
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 20.8333 5 yes
GO:0097435 supramolecular fiber organization 19.7917 4 yes
GO:0001934 positive regulation of protein phosphorylation 19.7917 8 yes
GO:0030334 regulation of cell migration 19.7917 5 yes
GO:0042127 regulation of cell population proliferation 19.7917 4 yes
GO:0051094 positive regulation of developmental process 19.7917 4 yes
GO:0051129 negative regulation of cellular component organization 18.7500 5 yes
GO:0071310 cellular response to organic substance 18.7500 4 yes
GO:0071705 nitrogen compound transport 18.7500 4 yes
GO:0080134 regulation of response to stress 18.7500 4 yes
GO:1901701 cellular response to oxygen-containing compound 17.7083 4 yes
GO:2000147 positive regulation of cell motility 17.7083 5 yes
GO:0006357 regulation of transcription by RNA polymerase II 17.7083 8 yes
GO:0030335 positive regulation of cell migration 17.7083 6 yes
GO:0040017 positive regulation of locomotion 17.7083 4 yes
GO:0051254 positive regulation of RNA metabolic process 16.6667 6 yes
GO:0015031 protein transport 16.6667 4 yes
GO:1902532 negative regulation of intracellular signal transduction 15.6250 6 yes
GO:1902680 positive regulation of RNA biosynthetic process 15.6250 7 yes
GO:0045893 positive regulation of DNA-templated transcription 15.6250 8 yes
GO:0007015 actin filament organization 14.5833 5 yes
GO:0010243 response to organonitrogen compound 14.5833 4 yes
GO:0032886 regulation of microtubule-based process 14.5833 4 yes
GO:0070507 regulation of microtubule cytoskeleton organization 13.5417 5 yes
GO:0006886 intracellular protein transport 13.5417 4 yes
GO:0043066 negative regulation of apoptotic process 13.5417 6 yes
GO:0043069 negative regulation of programmed cell death 13.5417 5 yes
GO:0051056 regulation of small GTPase mediated signal transduction 13.5417 6 yes
GO:0051240 positive regulation of multicellular organismal process 11.4583 4 yes
GO:0080135 regulation of cellular response to stress 11.4583 4 yes
GO:0045944 positive regulation of transcription by RNA polymerase II 11.4583 9 yes
GO:1902904 negative regulation of supramolecular fiber organization 10.4167 6 yes
GO:0010628 positive regulation of gene expression 10.4167 7 yes
GO:0010639 negative regulation of organelle organization 10.4167 6 yes
GO:0031110 regulation of microtubule polymerization or depolymerization 10.4167 6 yes
GO:0051494 negative regulation of cytoskeleton organization 9.3750 7 yes
GO:0071417 cellular response to organonitrogen compound 9.3750 4 yes
GO:1901699 cellular response to nitrogen compound 9.3750 4 yes
GO:0045597 positive regulation of cell differentiation 9.3750 5 yes
GO:0071345 cellular response to cytokine stimulus 8.3333 5 yes
GO:2001233 regulation of apoptotic signaling pathway 8.3333 5 yes
GO:0034097 response to cytokine 8.3333 4 yes
GO:0045664 regulation of neuron differentiation 8.3333 5 yes
GO:0062197 cellular response to chemical stress 7.2917 4 yes
GO:0140546 defense response to symbiont 7.2917 4 yes
GO:0035023 regulation of Rho protein signal transduction 7.2917 7 yes
GO:0043244 regulation of protein-containing complex disassembly 7.2917 5 yes
GO:1901879 regulation of protein depolymerization 6.2500 6 yes
GO:1901880 negative regulation of protein depolymerization 6.2500 7 yes
GO:0001817 regulation of cytokine production 6.2500 4 yes
GO:0043242 negative regulation of protein-containing complex disassembly 6.2500 6 yes
GO:0071356 cellular response to tumor necrosis factor 5.2083 6 yes
GO:2001234 negative regulation of apoptotic signaling pathway 5.2083 6 yes
GO:2001236 regulation of extrinsic apoptotic signaling pathway 5.2083 6 yes
GO:0031111 negative regulation of microtubule polymerization or depolymerization 5.2083 7 yes
GO:0034612 response to tumor necrosis factor 5.2083 5 yes
GO:0051091 positive regulation of DNA-binding transcription factor activity 5.2083 4 yes
GO:0051092 positive regulation of NF-kappaB transcription factor activity 5.2083 5 yes
GO:2001222 regulation of neuron migration 4.1667 6 yes
GO:2001242 regulation of intrinsic apoptotic signaling pathway 4.1667 6 yes
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 4.1667 7 yes
GO:0045666 positive regulation of neuron differentiation 4.1667 6 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 4.1667 8 yes
GO:0060544 regulation of necroptotic process 3.1250 6 yes
GO:0062098 regulation of programmed necrotic cell death 3.1250 5 yes
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 3.1250 7 yes
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 3.1250 8 yes
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 3.1250 5 yes
GO:2001224 positive regulation of neuron migration 3.1250 7 yes
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 3.1250 7 yes
GO:0007026 negative regulation of microtubule depolymerization 3.1250 7 yes
GO:0031114 regulation of microtubule depolymerization 3.1250 6 yes
GO:0032495 response to muramyl dipeptide 3.1250 4 yes
GO:0032680 regulation of tumor necrosis factor production 3.1250 6 yes
GO:0055059 asymmetric neuroblast division 2.0833 4 yes
GO:0060546 negative regulation of necroptotic process 2.0833 7 yes
GO:0062099 negative regulation of programmed necrotic cell death 2.0833 6 yes
GO:0071225 cellular response to muramyl dipeptide 2.0833 5 yes
GO:0071470 cellular response to osmotic stress 2.0833 4 yes
GO:0071474 cellular hyperosmotic response 2.0833 5 yes
GO:0106049 regulation of cellular response to osmotic stress 2.0833 5 yes
GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 2.0833 6 yes
GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 2.0833 7 yes
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 2.0833 6 yes
GO:0001819 positive regulation of cytokine production 2.0833 5 yes
GO:0006972 hyperosmotic response 2.0833 4 yes
GO:0032675 regulation of interleukin-6 production 2.0833 5 yes
GO:0032755 positive regulation of interleukin-6 production 2.0833 6 yes
GO:0032760 positive regulation of tumor necrosis factor production 2.0833 7 yes
GO:0047484 regulation of response to osmotic stress 2.0833 5 yes
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 2.0833 9 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
RAC1_HUMAN [view entry] [view interactions] Low throughput yes no
MARK2_HUMAN [view entry] [view interactions] Low throughput yes yes
PAK4_HUMAN [view interactions] Low throughput no yes
NEB1_HUMAN [view entry] [view interactions] Low throughput yes yes
KSR1_HUMAN [view interactions] Low throughput no yes
1433T_HUMAN [view entry] [view interactions] Low throughput yes yes
1433Z_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA2_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
RHOA_HUMAN [view entry] [view interactions] Low throughput yes yes
MARK3_HUMAN [view interactions] Low throughput no yes
RHOB_HUMAN [view entry] [view interactions] Low throughput yes no
FYB1_HUMAN [view interactions] Low throughput no no
ASAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRF_HUMAN [view entry] [view interactions] Low throughput yes yes
PAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP21_HUMAN [view interactions] Low throughput no no
NEB2_HUMAN [view entry] [view interactions] Low throughput yes yes
DYLT1_HUMAN [view interactions] Low throughput no no
OGG1_HUMAN [view interactions] Low throughput no yes
PAXI_HUMAN [view interactions] Low throughput no yes
HECD1_HUMAN [view interactions] High throughput no yes
TRI52_HUMAN [view interactions] High throughput no yes
ZBT44_HUMAN [view interactions] High throughput no yes
CIA2A_HUMAN [view interactions] High throughput no yes
UBXN6_HUMAN [view entry] [view interactions] High throughput yes yes
EFMT3_HUMAN [view interactions] High throughput no no
LUR1L_HUMAN [view interactions] High throughput no no
FBXW7_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
SIR6_HUMAN [view interactions] High throughput no yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
ANM1_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
ZRAN1_HUMAN [view interactions] High throughput no yes
CAVN3_HUMAN [view interactions] High throughput no no
PARPT_HUMAN [view interactions] High throughput no no
VIGLN_HUMAN [view entry] [view interactions] High throughput yes yes
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
SLX4_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
RICTR_HUMAN [view interactions] High throughput no yes
B3GN2_HUMAN [view interactions] High throughput no yes
UBE2H_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CSN7A_HUMAN [view interactions] High throughput no yes
KLC2_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX1_HUMAN [view entry] [view interactions] High throughput yes yes
PSME3_HUMAN [view interactions] High throughput no yes
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
SELH_HUMAN [view interactions] High throughput no yes
WASF1_HUMAN [view entry] [view interactions] High throughput yes yes
CAZA1_HUMAN [view entry] [view interactions] High throughput yes yes
TPM3_HUMAN [view entry] [view interactions] High throughput yes yes
DBNL_HUMAN [view entry] [view interactions] High throughput yes yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
TPM4_HUMAN [view entry] [view interactions] High throughput yes yes
RHG21_HUMAN [view entry] [view interactions] High throughput yes yes
RHG26_HUMAN [view entry] [view interactions] High throughput yes yes
RHG40_HUMAN [view interactions] High throughput no no
RHG42_HUMAN [view interactions] High throughput no yes
BBLN_HUMAN [view interactions] High throughput no yes
DAB2P_HUMAN [view entry] [view interactions] High throughput yes no
EPS8_HUMAN [view entry] [view interactions] High throughput yes yes
FCHO2_HUMAN [view interactions] High throughput no yes
PRIC1_HUMAN [view entry] [view interactions] High throughput yes yes
SYGP1_HUMAN [view entry] [view interactions] High throughput yes yes
CEGT_HUMAN [view interactions] High throughput no yes
ARHG7_HUMAN [view entry] [view interactions] High throughput yes yes
CHIO_HUMAN [view interactions] High throughput no yes
URP2_HUMAN [view interactions] High throughput no no
FGD4_HUMAN [view entry] [view interactions] High throughput yes yes
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
PRIC2_HUMAN [view entry] [view interactions] High throughput yes no
SRBS1_HUMAN [view entry] [view interactions] High throughput yes yes
VINEX_HUMAN [view interactions] High throughput no no
SRGP1_HUMAN [view interactions] High throughput no no
STRP2_HUMAN [view interactions] High throughput no yes
VINC_HUMAN [view entry] [view interactions] High throughput yes no
AP3B1_HUMAN [view entry] [view interactions] High throughput yes yes
HMGN2_HUMAN [view interactions] High throughput no no
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
DYN2_HUMAN [view entry] [view interactions] High throughput yes yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
WASC5_HUMAN [view interactions] High throughput no yes
WASC4_HUMAN [view interactions] High throughput no yes
FKB15_HUMAN [view entry] [view interactions] High throughput yes yes
WAC2A_HUMAN [view interactions] High throughput no yes
ARHG1_HUMAN [view interactions] High throughput no no
DOCK7_HUMAN [view entry] [view interactions] High throughput yes no
CKAP2_HUMAN [view interactions] High throughput no yes
MA7D3_HUMAN [view interactions] High throughput no no
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
ANR52_HUMAN [view interactions] High throughput no yes
PLST_HUMAN [view interactions] High throughput no yes
CAMP1_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
SKA1_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1S_HUMAN [view interactions] High throughput no no
MAP7_HUMAN [view interactions] High throughput no yes
MTUS1_HUMAN [view interactions] High throughput no no
NCK1_HUMAN [view interactions] High throughput no yes
GTSE1_HUMAN [view interactions] High throughput no no
2A5D_HUMAN [view entry] [view interactions] High throughput yes yes
CAMP2_HUMAN [view interactions] High throughput no yes
MA7D2_HUMAN [view interactions] High throughput no yes
DCLK1_HUMAN [view entry] [view interactions] High throughput yes yes
PDZ11_HUMAN [view interactions] High throughput no yes
C170B_HUMAN [view interactions] High throughput no yes
MAP9_HUMAN [view interactions] High throughput no no
DVL1_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD1_HUMAN [view interactions] High throughput no yes
SRP54_HUMAN [view interactions] High throughput no yes
ARHG2_HUMAN [view entry] [view interactions] High throughput yes yes
CLAP1_HUMAN [view entry] [view interactions] High throughput yes yes
NIN_HUMAN [view interactions] High throughput no no
MIC26_HUMAN [view entry] [view interactions] High throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
MARE3_HUMAN [view entry] [view interactions] High throughput yes yes
TRI36_HUMAN [view interactions] High throughput no no
1433F_HUMAN [view entry] [view interactions] High throughput yes yes
VP33B_HUMAN [view interactions] High throughput no yes
MARK4_HUMAN [view interactions] High throughput no yes
STING_HUMAN [view interactions] High throughput no yes
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
PPP6_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
1433B_HUMAN [view entry] [view interactions] High throughput yes yes
ANR28_HUMAN [view interactions] High throughput no no
PP6R1_HUMAN [view interactions] High throughput no no
2A5B_HUMAN [view interactions] High throughput no yes
2A5E_HUMAN [view interactions] High throughput no yes
PP2AB_HUMAN [view interactions] High throughput no yes
2A5A_HUMAN [view interactions] High throughput no yes
2ABA_HUMAN [view interactions] High throughput no yes
TRPM7_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC1_HUMAN [view interactions] High throughput no no
PRD16_HUMAN [view interactions] High throughput no no
MECOM_HUMAN [view interactions] High throughput no yes
KCRU_HUMAN [view entry] [view interactions] High throughput yes yes
PP6R3_HUMAN [view interactions] High throughput no yes
SORL_HUMAN [view interactions] High throughput no yes
PP2AA_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
1433S_HUMAN [view entry] [view interactions] High throughput yes yes
PEX14_HUMAN [view interactions] High throughput no yes
FOXO3_HUMAN [view interactions] High throughput no yes
M3K14_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
SNW1_HUMAN [view interactions] High throughput no yes
CDC5L_HUMAN [view interactions] High throughput no yes
PTBP3_HUMAN [view interactions] High throughput no no
USE1_HUMAN [view interactions] High throughput no yes
CYFP1_HUMAN [view entry] [view interactions] High throughput yes yes
FMR1_HUMAN [view entry] [view interactions] High throughput yes yes
FXR1_HUMAN [view entry] [view interactions] High throughput yes yes
MYCB2_HUMAN [view entry] [view interactions] High throughput yes no
PEX5R_HUMAN [view entry] [view interactions] High throughput yes yes
TNIK_HUMAN [view entry] [view interactions] High throughput yes yes
TSC1_HUMAN [view entry] [view interactions] High throughput yes yes
BMI1_HUMAN [view interactions] High throughput no yes
LN28A_HUMAN [view interactions] High throughput no no
BICD1_HUMAN [view interactions] High throughput no yes
MD13L_HUMAN [view interactions] High throughput no no
RP25L_HUMAN [view interactions] High throughput no yes
IKBD_HUMAN [view interactions] High throughput no no
IKBE_HUMAN [view entry] [view interactions] High throughput yes yes
WDR5_HUMAN [view interactions] High throughput no no
RAB38_HUMAN [view interactions] High throughput no no
NOTC1_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
AKA10_HUMAN [view interactions] High throughput no no
CE170_HUMAN [view interactions] High throughput no yes
SCLT1_HUMAN [view interactions] High throughput no yes
DCTN1_HUMAN [view entry] [view interactions] High throughput yes yes
CNTRL_HUMAN [view interactions] High throughput no yes
AKIP_HUMAN [view interactions] High throughput no yes
BET1_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
DYRK2_HUMAN [view interactions] High throughput no yes
ALK_HUMAN [view entry] [view interactions] High throughput yes yes
UFO_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
VGFR1_HUMAN [view interactions] High throughput no no
FLT3_HUMAN [view interactions] High throughput no no
VGFR3_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
MERTK_HUMAN [view interactions] High throughput no yes
PGFRB_HUMAN [view interactions] High throughput no yes
ROS1_HUMAN [view interactions] High throughput no no
PLCG1_HUMAN [view entry] [view interactions] High throughput yes yes
TAF10_HUMAN [view interactions] High throughput no yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
MMS19_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
RFA2_HUMAN [view interactions] High throughput no yes
RFA1_HUMAN [view interactions] High throughput no yes
EGFR_HUMAN [view interactions] High throughput no no
CP250_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
NXF1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
WDR83_HUMAN [view interactions] High throughput no yes
FGL1_HUMAN [view interactions] High throughput no no
NTRK1_HUMAN [view interactions] High throughput no yes
2AAA_HUMAN [view entry] [view interactions] High throughput yes no
KIFC1_HUMAN [view interactions] High throughput no yes
RAD18_HUMAN [view interactions] High throughput no yes
PAK5_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
UBE2A_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
RNF31_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
RECQ4_HUMAN [view interactions] High throughput no yes
PP6R2_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
BACH1_HUMAN [view interactions] High throughput no no
NR2C2_HUMAN [view interactions] High throughput no yes
HDAC2_HUMAN [view interactions] High throughput no yes
RU17_HUMAN [view interactions] High throughput no yes
PLK1_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
WWP2_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
MRCKA_HUMAN [view entry] [view interactions] High throughput yes yes
FUBP1_HUMAN [view interactions] High throughput no yes
LRC31_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
KIF14_HUMAN [view interactions] High throughput no no
KIF23_HUMAN [view interactions] High throughput no yes
BCAR1_HUMAN [view interactions] High throughput no yes
KCC2A_HUMAN [view entry] [view interactions] High throughput yes yes
RIGI_HUMAN [view interactions] High throughput no yes
BAG5_HUMAN [view entry] [view interactions] High throughput yes no
TULP3_HUMAN [view interactions] High throughput no yes
UFL1_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
TRI67_HUMAN [view interactions] High throughput no no
FZR1_HUMAN [view interactions] High throughput no no
ZNRF2_HUMAN [view interactions] High throughput no yes
FBSP1_HUMAN [view entry] [view interactions] High throughput yes no
SPB1_HUMAN [view interactions] High throughput no yes
SPSB4_HUMAN [view interactions] High throughput no no
PNMA2_HUMAN [view interactions] High throughput no yes
KCNE3_HUMAN [view interactions] High throughput no yes
RL26L_HUMAN [view interactions] High throughput no yes
HNRC2_HUMAN [view interactions] High throughput no no