AP3B1_HUMAN
Evidence for PS localization
Functions
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. [View more on UniProt]
Protein features
Binary interactions with known binding regions
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
Network
Isoforms
Disease-causing germline mutations
| Position | Amino acid | Mutation | Disease | Overlap with binding region |
|---|---|---|---|---|
| 580 | Leu | Arg | Hermansky-Pudlaksyndrome2(HPS2) | - |
Linear motifs
| ELM instance | Name | Type | Start | End | Partner |
|---|---|---|---|---|---|
| ELMI000432 | LIG_Clathr_ClatBox_1 | LIG | 818 | 822 | - |
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in AP3B1_HUMAN |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | 27.5862 | 4 | no |
| GO:0032555 | purine ribonucleotide binding | 27.5862 | 4 | no |
| GO:0035639 | purine ribonucleoside triphosphate binding | 27.5862 | 4 | no |
| GO:0019902 | phosphatase binding | 5.1724 | 4 | yes |
| GO:0019903 | protein phosphatase binding | 3.4483 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in AP3B1_HUMAN |
|---|---|---|---|---|
| GO:0008104 | protein localization | 60.3448 | 4 | yes |
| GO:0016192 | vesicle-mediated transport | 58.6207 | 4 | yes |
| GO:0048522 | positive regulation of cellular process | 51.7241 | 4 | yes |
| GO:0071702 | organic substance transport | 51.7241 | 4 | yes |
| GO:0071705 | nitrogen compound transport | 50.0000 | 4 | yes |
| GO:0051128 | regulation of cellular component organization | 50.0000 | 4 | no |
| GO:0015031 | protein transport | 48.2759 | 4 | yes |
| GO:0006996 | organelle organization | 46.5517 | 4 | yes |
| GO:0048523 | negative regulation of cellular process | 43.1034 | 4 | no |
| GO:0051049 | regulation of transport | 41.3793 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 37.9310 | 4 | yes |
| GO:0080090 | regulation of primary metabolic process | 37.9310 | 4 | yes |
| GO:0006886 | intracellular protein transport | 37.9310 | 4 | yes |
| GO:0031323 | regulation of cellular metabolic process | 37.9310 | 4 | yes |
| GO:0051171 | regulation of nitrogen compound metabolic process | 34.4828 | 4 | yes |
| GO:0022607 | cellular component assembly | 34.4828 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 34.4828 | 4 | yes |
| GO:0006897 | endocytosis | 32.7586 | 5 | no |
| GO:0010646 | regulation of cell communication | 32.7586 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 31.0345 | 5 | yes |
| GO:0010604 | positive regulation of macromolecule metabolic process | 29.3103 | 5 | yes |
| GO:0051173 | positive regulation of nitrogen compound metabolic process | 27.5862 | 5 | yes |
| GO:0010468 | regulation of gene expression | 27.5862 | 5 | yes |
| GO:0009966 | regulation of signal transduction | 25.8621 | 4 | no |
| GO:0051252 | regulation of RNA metabolic process | 24.1379 | 5 | yes |
| GO:1903506 | regulation of nucleic acid-templated transcription | 24.1379 | 7 | yes |
| GO:2001141 | regulation of RNA biosynthetic process | 24.1379 | 6 | yes |
| GO:0051246 | regulation of protein metabolic process | 24.1379 | 5 | no |
| GO:0006355 | regulation of DNA-templated transcription | 24.1379 | 6 | yes |
| GO:0009889 | regulation of biosynthetic process | 24.1379 | 4 | yes |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.1379 | 5 | yes |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | 24.1379 | 5 | yes |
| GO:0031326 | regulation of cellular biosynthetic process | 24.1379 | 5 | yes |
| GO:0061024 | membrane organization | 22.4138 | 4 | yes |
| GO:0060627 | regulation of vesicle-mediated transport | 22.4138 | 4 | no |
| GO:0007010 | cytoskeleton organization | 22.4138 | 5 | no |
| GO:0033043 | regulation of organelle organization | 22.4138 | 5 | no |
| GO:0043933 | protein-containing complex organization | 22.4138 | 4 | no |
| GO:0051129 | negative regulation of cellular component organization | 22.4138 | 5 | no |
| GO:0051130 | positive regulation of cellular component organization | 22.4138 | 5 | no |
| GO:0043412 | macromolecule modification | 22.4138 | 4 | yes |
| GO:0048584 | positive regulation of response to stimulus | 20.6897 | 4 | no |
| GO:0051050 | positive regulation of transport | 20.6897 | 4 | no |
| GO:0010647 | positive regulation of cell communication | 20.6897 | 5 | no |
| GO:0044087 | regulation of cellular component biogenesis | 20.6897 | 4 | no |
| GO:0030030 | cell projection organization | 20.6897 | 4 | no |
| GO:0036211 | protein modification process | 20.6897 | 4 | yes |
| GO:0045935 | positive regulation of nucleobase-containing compound metabolic process | 18.9655 | 6 | yes |
| GO:0009891 | positive regulation of biosynthetic process | 18.9655 | 5 | yes |
| GO:0031328 | positive regulation of cellular biosynthetic process | 18.9655 | 6 | yes |
| GO:0051254 | positive regulation of RNA metabolic process | 17.2414 | 6 | yes |
| GO:0051650 | establishment of vesicle localization | 17.2414 | 4 | yes |
| GO:0099111 | microtubule-based transport | 17.2414 | 4 | yes |
| GO:0006357 | regulation of transcription by RNA polymerase II | 17.2414 | 7 | yes |
| GO:0010557 | positive regulation of macromolecule biosynthetic process | 17.2414 | 6 | yes |
| GO:0010970 | transport along microtubule | 17.2414 | 4 | yes |
| GO:0030705 | cytoskeleton-dependent intracellular transport | 17.2414 | 4 | yes |
| GO:0033365 | protein localization to organelle | 17.2414 | 5 | yes |
| GO:0045893 | positive regulation of DNA-templated transcription | 15.5172 | 7 | yes |
| GO:0047496 | vesicle transport along microtubule | 15.5172 | 5 | yes |
| GO:0072384 | organelle transport along microtubule | 15.5172 | 4 | yes |
| GO:0099518 | vesicle cytoskeletal trafficking | 15.5172 | 5 | yes |
| GO:1902680 | positive regulation of RNA biosynthetic process | 15.5172 | 7 | yes |
| GO:1903508 | positive regulation of nucleic acid-templated transcription | 15.5172 | 8 | yes |
| GO:0008088 | axo-dendritic transport | 15.5172 | 5 | yes |
| GO:0016050 | vesicle organization | 15.5172 | 5 | yes |
| GO:0048489 | synaptic vesicle transport | 13.7931 | 4 | yes |
| GO:0048878 | chemical homeostasis | 13.7931 | 4 | yes |
| GO:0097479 | synaptic vesicle localization | 13.7931 | 4 | yes |
| GO:0098930 | axonal transport | 13.7931 | 6 | yes |
| GO:0007034 | vacuolar transport | 13.7931 | 4 | yes |
| GO:0008089 | anterograde axonal transport | 13.7931 | 7 | yes |
| GO:0045595 | regulation of cell differentiation | 12.0690 | 4 | yes |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | 12.0690 | 8 | yes |
| GO:0048490 | anterograde synaptic vesicle transport | 12.0690 | 7 | yes |
| GO:0050801 | ion homeostasis | 12.0690 | 5 | yes |
| GO:0051094 | positive regulation of developmental process | 12.0690 | 4 | yes |
| GO:0051240 | positive regulation of multicellular organismal process | 12.0690 | 4 | yes |
| GO:0072657 | protein localization to membrane | 12.0690 | 4 | yes |
| GO:0099514 | synaptic vesicle cytoskeletal transport | 12.0690 | 5 | yes |
| GO:0099517 | synaptic vesicle transport along microtubule | 12.0690 | 6 | yes |
| GO:0045597 | positive regulation of cell differentiation | 10.3448 | 5 | yes |
| GO:0048753 | pigment granule organization | 8.6207 | 6 | yes |
| GO:0050865 | regulation of cell activation | 8.6207 | 4 | yes |
| GO:0055065 | metal ion homeostasis | 8.6207 | 7 | yes |
| GO:0055080 | cation homeostasis | 8.6207 | 6 | yes |
| GO:0090304 | nucleic acid metabolic process | 8.6207 | 4 | yes |
| GO:0098771 | inorganic ion homeostasis | 8.6207 | 6 | yes |
| GO:0099003 | vesicle-mediated transport in synapse | 8.6207 | 5 | yes |
| GO:0002694 | regulation of leukocyte activation | 8.6207 | 4 | yes |
| GO:0007041 | lysosomal transport | 8.6207 | 5 | yes |
| GO:0022407 | regulation of cell-cell adhesion | 8.6207 | 5 | yes |
| GO:0030155 | regulation of cell adhesion | 8.6207 | 4 | yes |
| GO:0032438 | melanosome organization | 8.6207 | 7 | yes |
| GO:0045785 | positive regulation of cell adhesion | 6.8966 | 5 | yes |
| GO:0050867 | positive regulation of cell activation | 6.8966 | 5 | yes |
| GO:0051249 | regulation of lymphocyte activation | 6.8966 | 5 | yes |
| GO:0051251 | positive regulation of lymphocyte activation | 6.8966 | 6 | yes |
| GO:0072594 | establishment of protein localization to organelle | 6.8966 | 4 | yes |
| GO:2000026 | regulation of multicellular organismal development | 6.8966 | 4 | yes |
| GO:0002684 | positive regulation of immune system process | 6.8966 | 4 | yes |
| GO:0002696 | positive regulation of leukocyte activation | 6.8966 | 5 | yes |
| GO:0006605 | protein targeting | 6.8966 | 5 | yes |
| GO:0016070 | RNA metabolic process | 6.8966 | 5 | yes |
| GO:0022409 | positive regulation of cell-cell adhesion | 6.8966 | 6 | yes |
| GO:0046634 | regulation of alpha-beta T cell activation | 5.1724 | 7 | yes |
| GO:0046635 | positive regulation of alpha-beta T cell activation | 5.1724 | 8 | yes |
| GO:0048232 | male gamete generation | 5.1724 | 4 | yes |
| GO:0050776 | regulation of immune response | 5.1724 | 4 | yes |
| GO:0050863 | regulation of T cell activation | 5.1724 | 6 | yes |
| GO:0050870 | positive regulation of T cell activation | 5.1724 | 7 | yes |
| GO:0055076 | transition metal ion homeostasis | 5.1724 | 8 | yes |
| GO:0061462 | protein localization to lysosome | 5.1724 | 7 | yes |
| GO:0070142 | synaptic vesicle budding | 5.1724 | 6 | yes |
| GO:0072507 | divalent inorganic cation homeostasis | 5.1724 | 7 | yes |
| GO:0072665 | protein localization to vacuole | 5.1724 | 6 | yes |
| GO:0072666 | establishment of protein localization to vacuole | 5.1724 | 5 | yes |
| GO:1901362 | organic cyclic compound biosynthetic process | 5.1724 | 4 | yes |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 5.1724 | 6 | yes |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 5.1724 | 7 | yes |
| GO:0006623 | protein targeting to vacuole | 5.1724 | 5 | yes |
| GO:0006873 | cellular ion homeostasis | 5.1724 | 4 | yes |
| GO:0006875 | cellular metal ion homeostasis | 5.1724 | 6 | yes |
| GO:0006900 | vesicle budding from membrane | 5.1724 | 5 | yes |
| GO:0007005 | mitochondrion organization | 5.1724 | 5 | yes |
| GO:0007006 | mitochondrial membrane organization | 5.1724 | 5 | yes |
| GO:0019438 | aromatic compound biosynthetic process | 5.1724 | 4 | yes |
| GO:0030003 | cellular cation homeostasis | 5.1724 | 5 | yes |
| GO:0044271 | cellular nitrogen compound biosynthetic process | 5.1724 | 4 | yes |
| GO:0045580 | regulation of T cell differentiation | 3.4483 | 7 | yes |
| GO:0045582 | positive regulation of T cell differentiation | 3.4483 | 8 | yes |
| GO:0045619 | regulation of lymphocyte differentiation | 3.4483 | 6 | yes |
| GO:0045621 | positive regulation of lymphocyte differentiation | 3.4483 | 7 | yes |
| GO:0046637 | regulation of alpha-beta T cell differentiation | 3.4483 | 8 | yes |
| GO:0046638 | positive regulation of alpha-beta T cell differentiation | 3.4483 | 9 | yes |
| GO:0046916 | cellular transition metal ion homeostasis | 3.4483 | 7 | yes |
| GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib | 3.4483 | 4 | yes |
| GO:0048007 | antigen processing and presentation, exogenous lipid antigen via MHC class Ib | 3.4483 | 4 | yes |
| GO:0051136 | regulation of NK T cell differentiation | 3.4483 | 9 | yes |
| GO:0051138 | positive regulation of NK T cell differentiation | 3.4483 | 10 | yes |
| GO:0060155 | platelet dense granule organization | 3.4483 | 7 | yes |
| GO:0060429 | epithelium development | 3.4483 | 4 | yes |
| GO:0072503 | cellular divalent inorganic cation homeostasis | 3.4483 | 6 | yes |
| GO:0080171 | lytic vacuole organization | 3.4483 | 6 | yes |
| GO:0090150 | establishment of protein localization to membrane | 3.4483 | 4 | yes |
| GO:0097659 | nucleic acid-templated transcription | 3.4483 | 6 | yes |
| GO:1902105 | regulation of leukocyte differentiation | 3.4483 | 5 | yes |
| GO:1902107 | positive regulation of leukocyte differentiation | 3.4483 | 6 | yes |
| GO:1903706 | regulation of hemopoiesis | 3.4483 | 4 | yes |
| GO:1903708 | positive regulation of hemopoiesis | 3.4483 | 5 | yes |
| GO:0006351 | DNA-templated transcription | 3.4483 | 7 | yes |
| GO:0006366 | transcription by RNA polymerase II | 3.4483 | 8 | yes |
| GO:0006622 | protein targeting to lysosome | 3.4483 | 6 | yes |
| GO:0007033 | vacuole organization | 3.4483 | 5 | yes |
| GO:0007040 | lysosome organization | 3.4483 | 7 | yes |
| GO:0007599 | hemostasis | 3.4483 | 4 | yes |
| GO:0009059 | macromolecule biosynthetic process | 3.4483 | 4 | yes |
| GO:0016071 | mRNA metabolic process | 3.4483 | 6 | yes |
| GO:0016182 | synaptic vesicle budding from endosome | 3.4483 | 4 | yes |
| GO:0018130 | heterocycle biosynthetic process | 3.4483 | 4 | yes |
| GO:0030099 | myeloid cell differentiation | 3.4483 | 4 | yes |
| GO:0032774 | RNA biosynthetic process | 3.4483 | 5 | yes |
| GO:0033363 | secretory granule organization | 3.4483 | 6 | yes |
| GO:0034394 | protein localization to cell surface | 3.4483 | 5 | yes |
| GO:0034654 | nucleobase-containing compound biosynthetic process | 3.4483 | 4 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| KIF3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ANK3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRRK2_HUMAN | [view interactions] | Low throughput | no | yes |
| AP3S2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| SEPT7_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| LRSM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ZNT3_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| ARF5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARF6_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| AP3D1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
| ARF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
| BTK_HUMAN | [view interactions] | High throughput | no | no |
| XPOT_HUMAN | [view interactions] | High throughput | no | no |
| DYLT1_HUMAN | [view interactions] | High throughput | no | no |
| CAVN1_HUMAN | [view interactions] | High throughput | no | no |
| E41L3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NU155_HUMAN | [view interactions] | High throughput | no | yes |
| 1433Z_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| SKA3_HUMAN | [view interactions] | High throughput | no | no |
| DLG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| NLRP3_HUMAN | [view interactions] | High throughput | no | yes |
| KSR1_HUMAN | [view interactions] | High throughput | no | yes |
| VTI1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CSCL1_HUMAN | [view interactions] | High throughput | no | no |
| TPC2_HUMAN | [view interactions] | High throughput | no | no |
| PI42A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AP3M2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| E41L2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PESC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CR3L1_HUMAN | [view interactions] | High throughput | no | yes |
| AP3S1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FAM9A_HUMAN | [view interactions] | High throughput | no | no |
| VASN_HUMAN | [view interactions] | High throughput | no | yes |
| AP3M1_HUMAN | [view interactions] | High throughput | no | yes |
| ERMAP_HUMAN | [view interactions] | High throughput | no | yes |
| MECOM_HUMAN | [view interactions] | High throughput | no | yes |
| BMX_HUMAN | [view interactions] | High throughput | no | no |
| RUVB1_HUMAN | [view interactions] | High throughput | no | yes |
| DUS14_HUMAN | [view interactions] | High throughput | no | yes |
| K2C8_HUMAN | [view interactions] | High throughput | no | no |
| PI4KB_HUMAN | [view interactions] | High throughput | no | yes |
| XPO1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAMKV_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARRB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ARRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SNW1_HUMAN | [view interactions] | High throughput | no | yes |
| PTBP3_HUMAN | [view interactions] | High throughput | no | no |
| JUN_HUMAN | [view interactions] | High throughput | no | yes |
| RYBP_HUMAN | [view interactions] | High throughput | no | no |
| IDLC_HUMAN | [view interactions] | High throughput | no | no |
| OPTN_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| HD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RAB30_HUMAN | [view interactions] | High throughput | no | yes |
| RAB32_HUMAN | [view interactions] | High throughput | no | yes |
| ESR1_HUMAN | [view interactions] | High throughput | no | no |
| CENPJ_HUMAN | [view interactions] | High throughput | no | no |
| LAMP1_HUMAN | [view interactions] | High throughput | no | yes |
| TGON2_HUMAN | [view interactions] | High throughput | no | yes |
| VGFR1_HUMAN | [view interactions] | High throughput | no | no |
| LMTK1_HUMAN | [view interactions] | High throughput | no | yes |
| STYK1_HUMAN | [view interactions] | High throughput | no | yes |
| CC154_HUMAN | [view interactions] | High throughput | no | no |
| NOLC1_HUMAN | [view interactions] | High throughput | no | yes |
| E2AK1_HUMAN | [view interactions] | High throughput | no | yes |
| MCM3_HUMAN | [view interactions] | High throughput | no | no |
| DPOD1_HUMAN | [view interactions] | High throughput | no | yes |
| ATRX_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MFAP1_HUMAN | [view interactions] | High throughput | no | yes |
| PR38A_HUMAN | [view interactions] | High throughput | no | no |
| NAF1_HUMAN | [view interactions] | High throughput | no | yes |
| EAF1_HUMAN | [view interactions] | High throughput | no | yes |
| RBM14_HUMAN | [view interactions] | High throughput | no | yes |
| DDX20_HUMAN | [view interactions] | High throughput | no | no |
| GKAP1_HUMAN | [view interactions] | High throughput | no | no |
| GRK5_HUMAN | [view interactions] | High throughput | no | yes |
| EED_HUMAN | [view interactions] | High throughput | no | yes |
| SNX11_HUMAN | [view interactions] | High throughput | no | yes |
| AGO3_HUMAN | [view interactions] | High throughput | no | yes |
| CREB3_HUMAN | [view interactions] | High throughput | no | no |
| DTBP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EDA_HUMAN | [view interactions] | High throughput | no | no |
| PE2R3_HUMAN | [view interactions] | High throughput | no | no |
| NTRK1_HUMAN | [view interactions] | High throughput | no | yes |
| LYPL1_HUMAN | [view interactions] | High throughput | no | yes |
| RAD18_HUMAN | [view interactions] | High throughput | no | yes |
| FGF8_HUMAN | [view interactions] | High throughput | no | no |
| E41L5_HUMAN | [view interactions] | High throughput | no | no |
| TRI25_HUMAN | [view interactions] | High throughput | no | yes |
| HDAC4_HUMAN | [view interactions] | High throughput | no | yes |
| U5S1_HUMAN | [view interactions] | High throughput | no | yes |
| ESR2_HUMAN | [view interactions] | High throughput | no | no |
| LARP7_HUMAN | [view interactions] | High throughput | no | yes |
| CGAS_HUMAN | [view interactions] | High throughput | no | yes |
| WDR76_HUMAN | [view interactions] | High throughput | no | no |
| H4_HUMAN | [view interactions] | High throughput | no | yes |
| H2A1B_HUMAN | [view interactions] | High throughput | no | yes |
| NR2C2_HUMAN | [view interactions] | High throughput | no | yes |
| ATX1_HUMAN | [view interactions] | High throughput | no | yes |
| DYR1A_HUMAN | [view interactions] | High throughput | no | yes |
| DUS28_HUMAN | [view interactions] | High throughput | no | yes |
| TPTE2_HUMAN | [view interactions] | High throughput | no | no |
| BIRC3_HUMAN | [view interactions] | High throughput | no | no |
| LMBRL_HUMAN | [view interactions] | High throughput | no | no |
| TIF1B_HUMAN | [view interactions] | High throughput | no | yes |
| PKHA4_HUMAN | [view interactions] | High throughput | no | yes |
| KIF14_HUMAN | [view interactions] | High throughput | no | no |
| CTIP_HUMAN | [view interactions] | High throughput | no | no |
| CUL4A_HUMAN | [view interactions] | High throughput | no | no |
| FA20C_HUMAN | [view interactions] | High throughput | no | no |
| SYVN1_HUMAN | [view interactions] | High throughput | no | yes |
| ZNRF4_HUMAN | [view interactions] | High throughput | no | no |
| P53_HUMAN | [view interactions] | High throughput | no | no |
| M4K2_HUMAN | [view interactions] | High throughput | no | yes |
| M4K4_HUMAN | [view interactions] | High throughput | no | yes |
| MINK1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PLCD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CR3L3_HUMAN | [view interactions] | High throughput | no | no |
| PKHJ1_HUMAN | [view interactions] | High throughput | no | yes |
| PNM8A_HUMAN | [view interactions] | High throughput | no | yes |
| LRRT4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| ZN460_HUMAN | [view interactions] | High throughput | no | no |
| SYT2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| PI42C_HUMAN | [view interactions] | High throughput | no | yes |
| HEN2_HUMAN | [view interactions] | High throughput | no | no |
| UTP23_HUMAN | [view interactions] | High throughput | no | no |
| E41L1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TFPI2_HUMAN | [view interactions] | High throughput | no | no |
| SEC62_HUMAN | [view interactions] | High throughput | no | yes |
| FGRL1_HUMAN | [view interactions] | High throughput | no | yes |
| WIF1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RM42_HUMAN | [view interactions] | High throughput | no | yes |
| FGFP1_HUMAN | [view interactions] | High throughput | no | no |
| KDM4B_HUMAN | [view interactions] | High throughput | no | no |
| HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| IKBL1_HUMAN | [view interactions] | High throughput | no | no |
| EP300_HUMAN | [view interactions] | High throughput | no | yes |
| FBX32_HUMAN | [view interactions] | High throughput | no | no |
| BRD9_HUMAN | [view interactions] | High throughput | no | yes |
| ATR_HUMAN | [view interactions] | High throughput | no | no |
| ATM_HUMAN | [view interactions] | High throughput | no | yes |
| COG3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CD11A_HUMAN | [view interactions] | High throughput | no | yes |
| CDC73_HUMAN | [view interactions] | High throughput | no | yes |
| JMJD6_HUMAN | [view interactions] | High throughput | no | yes |
| PELP1_HUMAN | [view interactions] | High throughput | no | yes |
| CAZA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKB15_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| WAC2A_HUMAN | [view interactions] | High throughput | no | yes |
| WASC5_HUMAN | [view interactions] | High throughput | no | yes |
| AGR2_HUMAN | [view interactions] | High throughput | no | no |
| VIR_HUMAN | [view interactions] | High throughput | no | yes |
| GCR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| DNJC5_HUMAN | [view interactions] | High throughput | no | yes |
| CLCA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| CLCB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| LTOR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BROMI_HUMAN | [view interactions] | High throughput | no | no |
| SLN11_HUMAN | [view interactions] | High throughput | no | yes |
| CD63_HUMAN | [view interactions] | Computational | no | no |
| SNX9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| KCC2D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| VAMP7_HUMAN | [view interactions] | Computational | no | yes |
| P3C2A_HUMAN | [view interactions] | Computational | no | yes |
| PICAL_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| SNX2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| SNAPN_HUMAN | [view interactions] | Computational | no | yes |
| AP1G1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| HIP1R_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AP1M2_HUMAN | [view interactions] | Computational | no | no |
| AP4B1_HUMAN | [view interactions] | Computational | no | yes |
| RAB5C_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| JAK2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| RAF1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
| AP3B2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| CBPD_HUMAN | [view interactions] | Computational | no | yes |
| AP1M1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| GAK_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| TFR1_HUMAN | [view interactions] | Computational | no | yes |
| AUXI_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| MPRI_HUMAN | [view interactions] | Computational | no | yes |
| KCC2B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| AP4E1_HUMAN | [view interactions] | Computational | no | no |
| NECP1_HUMAN | [view interactions] | Computational | no | no |
| SNX5_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
| OCRL_HUMAN | [view interactions] | Computational | no | yes |
| SORT_HUMAN | [view interactions] | Computational | no | yes |
| YIPF6_HUMAN | [view interactions] | Computational | no | yes |