Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ZNT3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Involved in accumulation of zinc in synaptic vesicles. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in ZNT3_HUMAN
GO:0043169 cation binding 33.3333 4 yes
GO:0046872 metal ion binding 33.3333 5 yes
GO:0005385 zinc ion transmembrane transporter activity 25.0000 7 yes
GO:0008324 monoatomic cation transmembrane transporter activity 25.0000 4 yes
GO:0015291 secondary active transmembrane transporter activity 25.0000 4 yes
GO:0015297 antiporter activity 25.0000 5 yes
GO:0022890 inorganic cation transmembrane transporter activity 25.0000 4 yes
GO:0046873 metal ion transmembrane transporter activity 25.0000 5 yes
GO:0046915 transition metal ion transmembrane transporter activity 25.0000 6 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ZNT3_HUMAN
GO:0051049 regulation of transport 58.3333 4 yes
GO:0006996 organelle organization 58.3333 4 no
GO:0010646 regulation of cell communication 58.3333 4 no
GO:0048522 positive regulation of cellular process 50.0000 4 no
GO:0061024 membrane organization 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0000041 transition metal ion transport 41.6667 7 yes
GO:0006811 monoatomic ion transport 41.6667 4 yes
GO:0006812 monoatomic cation transport 41.6667 5 yes
GO:0030001 metal ion transport 41.6667 6 yes
GO:0008104 protein localization 41.6667 4 no
GO:0015031 protein transport 41.6667 4 no
GO:0016050 vesicle organization 41.6667 5 no
GO:0022607 cellular component assembly 41.6667 4 no
GO:0050804 modulation of chemical synaptic transmission 41.6667 5 no
GO:0071702 organic substance transport 41.6667 4 no
GO:0071705 nitrogen compound transport 41.6667 4 no
GO:0099177 regulation of trans-synaptic signaling 41.6667 4 no
GO:0009889 regulation of biosynthetic process 41.6667 4 no
GO:0009891 positive regulation of biosynthetic process 41.6667 5 no
GO:0009893 positive regulation of metabolic process 41.6667 4 no
GO:0010468 regulation of gene expression 41.6667 6 no
GO:0010556 regulation of macromolecule biosynthetic process 41.6667 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 41.6667 6 no
GO:0010604 positive regulation of macromolecule metabolic process 41.6667 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 41.6667 5 no
GO:0031323 regulation of cellular metabolic process 41.6667 4 no
GO:0031325 positive regulation of cellular metabolic process 41.6667 5 no
GO:0031326 regulation of cellular biosynthetic process 41.6667 5 no
GO:0031328 positive regulation of cellular biosynthetic process 41.6667 6 no
GO:0048523 negative regulation of cellular process 41.6667 4 no
GO:0006829 zinc ion transport 33.3333 8 yes
GO:0007034 vacuolar transport 33.3333 4 yes
GO:0007041 lysosomal transport 33.3333 5 yes
GO:0062111 zinc ion import into organelle 33.3333 6 yes
GO:0071577 zinc ion transmembrane transport 33.3333 5 yes
GO:0098655 monoatomic cation transmembrane transport 33.3333 4 yes
GO:0098662 inorganic cation transmembrane transport 33.3333 4 yes
GO:0071310 cellular response to organic substance 33.3333 4 no
GO:0098657 import into cell 33.3333 4 no
GO:0009966 regulation of signal transduction 33.3333 4 no
GO:0002684 positive regulation of immune system process 33.3333 4 no
GO:0006355 regulation of DNA-templated transcription 33.3333 7 no
GO:0006873 intracellular monoatomic ion homeostasis 33.3333 4 no
GO:0030003 intracellular monoatomic cation homeostasis 33.3333 5 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 33.3333 5 no
GO:0051240 positive regulation of multicellular organismal process 33.3333 4 no
GO:0051252 regulation of RNA metabolic process 33.3333 5 no
GO:0055080 monoatomic cation homeostasis 33.3333 4 no
GO:2001141 regulation of RNA biosynthetic process 33.3333 6 no
GO:0051128 regulation of cellular component organization 33.3333 4 no
GO:0010038 response to metal ion 25.0000 4 yes
GO:0051050 positive regulation of transport 25.0000 4 yes
GO:0140916 zinc ion import into lysosome 25.0000 4 yes
GO:0010647 positive regulation of cell communication 25.0000 5 no
GO:0023056 positive regulation of signaling 25.0000 4 no
GO:0032880 regulation of protein localization 25.0000 5 no
GO:0034762 regulation of transmembrane transport 25.0000 4 no
GO:0051046 regulation of secretion 25.0000 5 no
GO:0060341 regulation of cellular localization 25.0000 4 no
GO:0060627 regulation of vesicle-mediated transport 25.0000 4 no
GO:0072657 protein localization to membrane 25.0000 4 no
GO:1903530 regulation of secretion by cell 25.0000 4 no
GO:0048499 synaptic vesicle membrane organization 25.0000 5 no
GO:0002694 regulation of leukocyte activation 25.0000 4 no
GO:0002696 positive regulation of leukocyte activation 25.0000 5 no
GO:0006357 regulation of transcription by RNA polymerase II 25.0000 8 no
GO:0006886 intracellular protein transport 25.0000 4 no
GO:0008088 axo-dendritic transport 25.0000 5 no
GO:0010970 transport along microtubule 25.0000 4 no
GO:0022407 regulation of cell-cell adhesion 25.0000 5 no
GO:0022409 positive regulation of cell-cell adhesion 25.0000 6 no
GO:0030155 regulation of cell adhesion 25.0000 4 no
GO:0030705 cytoskeleton-dependent intracellular transport 25.0000 4 no
GO:0033365 protein localization to organelle 25.0000 5 no
GO:0045595 regulation of cell differentiation 25.0000 4 no
GO:0045785 positive regulation of cell adhesion 25.0000 5 no
GO:0045893 positive regulation of DNA-templated transcription 25.0000 8 no
GO:0045944 positive regulation of transcription by RNA polymerase II 25.0000 9 no
GO:0048584 positive regulation of response to stimulus 25.0000 4 no
GO:0050863 regulation of T cell activation 25.0000 6 no
GO:0050865 regulation of cell activation 25.0000 4 no
GO:0050867 positive regulation of cell activation 25.0000 5 no
GO:0050870 positive regulation of T cell activation 25.0000 7 no
GO:0051094 positive regulation of developmental process 25.0000 4 no
GO:0051249 regulation of lymphocyte activation 25.0000 5 no
GO:0051251 positive regulation of lymphocyte activation 25.0000 6 no
GO:0051254 positive regulation of RNA metabolic process 25.0000 6 no
GO:0072594 establishment of protein localization to organelle 25.0000 4 no
GO:0080134 regulation of response to stress 25.0000 4 no
GO:0099111 microtubule-based transport 25.0000 4 no
GO:1902680 positive regulation of RNA biosynthetic process 25.0000 7 no
GO:1903037 regulation of leukocyte cell-cell adhesion 25.0000 6 no
GO:1903039 positive regulation of leukocyte cell-cell adhesion 25.0000 7 no
GO:0010628 positive regulation of gene expression 25.0000 7 no
GO:0010639 negative regulation of organelle organization 25.0000 6 no
GO:0033043 regulation of organelle organization 25.0000 5 no
GO:0042127 regulation of cell population proliferation 25.0000 4 no
GO:0044087 regulation of cellular component biogenesis 25.0000 4 no
GO:0051129 negative regulation of cellular component organization 25.0000 5 no
GO:0051246 regulation of protein metabolic process 25.0000 5 no
GO:0009892 negative regulation of metabolic process 25.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 25.0000 5 no
GO:0010043 response to zinc ion 16.6667 5 yes
GO:0099180 zinc ion import into synaptic vesicle 16.6667 7 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
ZNT10_HUMAN [view interactions] Low throughput no yes
ZNT2_HUMAN [view interactions] Low throughput no no
ZNT4_HUMAN [view interactions] Low throughput no no
TM163_HUMAN [view interactions] Low throughput no no
TFR1_HUMAN [view entry] [view interactions] Low throughput yes yes
AP3B1_HUMAN [view entry] [view interactions] Low throughput yes yes
SYPH_HUMAN [view entry] [view interactions] Low throughput yes yes
VAMP2_HUMAN [view entry] [view interactions] High throughput yes no
ITM2B_HUMAN [view interactions] High throughput no yes
NADL2_HUMAN [view interactions] High throughput no yes
OCAD1_HUMAN [view interactions] High throughput no yes
TNR5_HUMAN [view interactions] High throughput no no
SOAT_HUMAN [view interactions] High throughput no no
CGRF1_HUMAN [view interactions] High throughput no yes
RETR3_HUMAN [view interactions] High throughput no yes
SCN3B_HUMAN [view interactions] High throughput no no
CXA8_HUMAN [view interactions] High throughput no no
TM14B_HUMAN [view interactions] High throughput no no
GP152_HUMAN [view interactions] High throughput no no
GPX8_HUMAN [view interactions] High throughput no no
TM242_HUMAN [view interactions] High throughput no yes
RN19B_HUMAN [view interactions] High throughput no yes
GOLM1_HUMAN [view interactions] High throughput no yes
DHB13_HUMAN [view interactions] High throughput no yes
ELOV4_HUMAN [view interactions] High throughput no no
SGPL1_HUMAN [view interactions] High throughput no yes
GPR42_HUMAN [view interactions] High throughput no no
ZNT8_HUMAN [view interactions] High throughput no no
ZNT3_HUMAN [view entry] [view interactions] High throughput yes yes
ZNT1_HUMAN [view entry] [view interactions] High throughput yes no
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
S35C2_HUMAN [view interactions] High throughput no yes
RTN3_HUMAN [view entry] [view interactions] High throughput yes yes
NPT2B_HUMAN [view interactions] High throughput no no
FCRL3_HUMAN [view interactions] High throughput no no
RC3H1_HUMAN [view interactions] High throughput no yes
KCNE4_HUMAN [view interactions] High throughput no no
KCNE3_HUMAN [view interactions] High throughput no yes
TSN8_HUMAN [view interactions] High throughput no no
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
DNJC5_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
AP3D1_HUMAN [view entry] [view interactions] High throughput yes no
LAMP3_HUMAN [view interactions] High throughput no no