Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

SYPH_HUMAN

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity . [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in SYPH_HUMAN
GO:0043169 cation binding 26.1538 4 no
GO:0046872 metal ion binding 26.1538 5 no
GO:0043168 anion binding 24.6154 4 no
GO:0042169 SH2 domain binding 4.6154 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in SYPH_HUMAN
GO:0048522 positive regulation of cellular process 64.6154 4 no
GO:0051049 regulation of transport 50.7692 4 yes
GO:0010646 regulation of cell communication 46.1538 4 yes
GO:0051128 regulation of cellular component organization 41.5385 4 no
GO:0048523 negative regulation of cellular process 38.4615 4 no
GO:0006996 organelle organization 36.9231 4 yes
GO:0098657 import into cell 36.9231 4 yes
GO:0009893 positive regulation of metabolic process 36.9231 4 no
GO:0031323 regulation of cellular metabolic process 36.9231 4 no
GO:0060255 regulation of macromolecule metabolic process 35.3846 4 no
GO:0009966 regulation of signal transduction 33.8462 4 yes
GO:0022607 cellular component assembly 33.8462 4 no
GO:0051050 positive regulation of transport 32.3077 4 no
GO:0031325 positive regulation of cellular metabolic process 30.7692 5 no
GO:0080090 regulation of primary metabolic process 30.7692 4 no
GO:0010604 positive regulation of macromolecule metabolic process 29.2308 5 no
GO:0071702 organic substance transport 27.6923 4 no
GO:0008104 protein localization 26.1538 4 no
GO:0071705 nitrogen compound transport 26.1538 4 no
GO:0051130 positive regulation of cellular component organization 26.1538 5 no
GO:0009889 regulation of biosynthetic process 26.1538 4 no
GO:0030030 cell projection organization 26.1538 4 no
GO:0051046 regulation of secretion 24.6154 5 yes
GO:0061024 membrane organization 24.6154 4 yes
GO:0010647 positive regulation of cell communication 24.6154 5 no
GO:0023056 positive regulation of signaling 24.6154 4 no
GO:0031326 regulation of cellular biosynthetic process 24.6154 5 no
GO:0044087 regulation of cellular component biogenesis 24.6154 4 no
GO:0048584 positive regulation of response to stimulus 24.6154 4 no
GO:0050804 modulation of chemical synaptic transmission 23.0769 5 yes
GO:0099177 regulation of trans-synaptic signaling 23.0769 4 yes
GO:0010556 regulation of macromolecule biosynthetic process 23.0769 5 no
GO:0060627 regulation of vesicle-mediated transport 21.5385 4 yes
GO:1903530 regulation of secretion by cell 21.5385 4 yes
GO:0009891 positive regulation of biosynthetic process 21.5385 5 no
GO:0010468 regulation of gene expression 21.5385 6 no
GO:0051246 regulation of protein metabolic process 21.5385 5 no
GO:0016050 vesicle organization 16.9231 5 yes
GO:0071310 cellular response to organic substance 16.9231 4 yes
GO:0048488 synaptic vesicle endocytosis 15.3846 5 yes
GO:0140238 presynaptic endocytosis 15.3846 4 yes
GO:0017157 regulation of exocytosis 13.8462 5 yes
GO:0048168 regulation of neuronal synaptic plasticity 9.2308 4 yes
GO:0051588 regulation of neurotransmitter transport 9.2308 5 yes
GO:1903305 regulation of regulated secretory pathway 9.2308 6 yes
GO:0046928 regulation of neurotransmitter secretion 7.6923 5 yes
GO:0048169 regulation of long-term neuronal synaptic plasticity 7.6923 5 yes
GO:0008277 regulation of G protein-coupled receptor signaling pathway 6.1538 5 yes
GO:0048499 synaptic vesicle membrane organization 6.1538 5 yes
GO:2000300 regulation of synaptic vesicle exocytosis 4.6154 6 yes
GO:0048172 regulation of short-term neuronal synaptic plasticity 3.0769 5 yes
GO:2000474 regulation of opioid receptor signaling pathway 3.0769 6 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
GAB1_HUMAN [view interactions] Low throughput no yes
SCAM1_HUMAN [view interactions] Low throughput no no
STMN3_HUMAN [view interactions] Low throughput no yes
RND2_HUMAN [view interactions] Low throughput no no
HOME2_HUMAN [view entry] [view interactions] Low throughput yes yes
HGS_HUMAN [view entry] [view interactions] Low throughput yes yes
ZNT10_HUMAN [view interactions] Low throughput no yes
ZNT3_HUMAN [view entry] [view interactions] Low throughput yes yes
OPRM_HUMAN [view entry] [view interactions] Low throughput yes no
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
MYO5B_HUMAN [view entry] [view interactions] Low throughput yes yes
GRIA1_HUMAN [view entry] [view interactions] Low throughput yes yes
VAMP2_HUMAN [view entry] [view interactions] Low throughput yes no
PRAF1_HUMAN [view interactions] Low throughput no yes
RAB3A_HUMAN [view entry] [view interactions] Low throughput yes yes
SNP25_HUMAN [view entry] [view interactions] Low throughput yes yes
SRCN1_HUMAN [view entry] [view interactions] Low throughput yes yes
SYT1_HUMAN [view entry] [view interactions] Low throughput yes no
SPN90_HUMAN [view entry] [view interactions] Low throughput yes no
FXL20_HUMAN [view interactions] Low throughput no no
AP1G1_HUMAN [view entry] [view interactions] Low throughput yes yes
SH3K1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN1_HUMAN [view entry] [view interactions] Low throughput yes yes
DYN2_HUMAN [view entry] [view interactions] Low throughput yes yes
ARFP2_HUMAN [view interactions] Low throughput no no
CDK16_HUMAN [view interactions] Low throughput no yes
CALX_HUMAN [view entry] [view interactions] Low throughput yes yes
DNJC5_HUMAN [view interactions] Low throughput no yes
SIAH1_HUMAN [view interactions] Low throughput no yes
SIAH2_HUMAN [view interactions] Low throughput no no
STX1A_HUMAN [view entry] [view interactions] Low throughput yes yes
PARK7_HUMAN [view entry] [view interactions] Low throughput yes yes
SNG3_HUMAN [view entry] [view interactions] Low throughput yes no
VINEX_HUMAN [view interactions] Low throughput no no
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRB2_HUMAN [view entry] [view interactions] Low throughput yes yes
RAB26_HUMAN [view interactions] Low throughput no no
PRIO_HUMAN [view entry] [view interactions] Low throughput yes yes
TSYL1_HUMAN [view interactions] High throughput no yes
DSG4_HUMAN [view interactions] High throughput no no
S27A4_HUMAN [view entry] [view interactions] High throughput yes yes
S20A1_HUMAN [view interactions] High throughput no yes
TPC_HUMAN [view interactions] High throughput no no
ETV3_HUMAN [view interactions] High throughput no yes
T184B_HUMAN [view interactions] High throughput no yes
PRRT2_HUMAN [view entry] [view interactions] High throughput yes no
UBP48_HUMAN [view interactions] High throughput no yes
NDUS5_HUMAN [view interactions] High throughput no yes
SC6A1_HUMAN [view entry] [view interactions] High throughput yes no
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] High throughput yes yes
NEGR1_HUMAN [view entry] [view interactions] High throughput yes yes
ALDOC_HUMAN [view entry] [view interactions] High throughput yes yes
CNTN1_HUMAN [view entry] [view interactions] High throughput yes yes
GNAO_HUMAN [view entry] [view interactions] High throughput yes yes
NPTN_HUMAN [view entry] [view interactions] High throughput yes yes
MYPR_HUMAN [view entry] [view interactions] High throughput yes yes
SYT2_HUMAN [view entry] [view interactions] High throughput yes no
QCR6L_HUMAN [view interactions] High throughput no yes
QCR6_HUMAN [view interactions] High throughput no yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
LANC1_HUMAN [view entry] [view interactions] High throughput yes yes
CNTP2_HUMAN [view entry] [view interactions] High throughput yes yes
CBPZ_HUMAN [view interactions] High throughput no no
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
NUFP1_HUMAN [view interactions] High throughput no yes
ATP9A_HUMAN [view interactions] High throughput no yes
GDC_HUMAN [view interactions] High throughput no no
GLPK_HUMAN [view entry] [view interactions] High throughput yes no
PTPS_HUMAN [view interactions] High throughput no yes
RN5A_HUMAN [view interactions] High throughput no yes
S20A2_HUMAN [view interactions] High throughput no yes
EXT1_HUMAN [view interactions] High throughput no yes
TM164_HUMAN [view interactions] High throughput no yes
T183A_HUMAN [view interactions] High throughput no no
TM87A_HUMAN [view interactions] High throughput no yes
TM186_HUMAN [view interactions] High throughput no no
ARL5B_HUMAN [view interactions] High throughput no yes
SCMC3_HUMAN [view interactions] High throughput no yes
SFXN3_HUMAN [view entry] [view interactions] High throughput yes yes
SGPP1_HUMAN [view interactions] High throughput no no
ARV1_HUMAN [view interactions] High throughput no yes
S38AA_HUMAN [view interactions] High throughput no yes
MRS2_HUMAN [view interactions] High throughput no no
HD_HUMAN [view entry] [view interactions] High throughput yes yes
APBB1_HUMAN [view entry] [view interactions] High throughput yes yes
VATL_HUMAN [view interactions] High throughput no no
TBA1C_HUMAN [view interactions] High throughput no yes
VPP1_HUMAN [view entry] [view interactions] High throughput yes yes
CALM2_HUMAN [view entry] [view interactions] High throughput yes yes
THY1_HUMAN [view entry] [view interactions] High throughput yes yes
ACTG_HUMAN [view entry] [view interactions] High throughput yes yes
GNAT2_HUMAN [view interactions] High throughput no no
EAA2_HUMAN [view entry] [view interactions] High throughput yes no
TBB4B_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
SNX1_HUMAN [view entry] [view interactions] High throughput yes yes
MTEF3_HUMAN [view interactions] High throughput no no
PPIF_HUMAN [view interactions] High throughput no no
MID51_HUMAN [view interactions] High throughput no no
RRFM_HUMAN [view interactions] High throughput no yes
BY55_HUMAN [view interactions] High throughput no no
SHLB1_HUMAN [view interactions] High throughput no yes
MYG1_HUMAN [view interactions] High throughput no yes
JOS2_HUMAN [view interactions] High throughput no no
PLIN3_HUMAN [view interactions] High throughput no yes
CAND2_HUMAN [view entry] [view interactions] High throughput yes no
DBLOH_HUMAN [view interactions] High throughput no no
SYFM_HUMAN [view interactions] High throughput no yes
PTN9_HUMAN [view interactions] High throughput no yes
HSFX1_HUMAN [view interactions] High throughput no no
PTCD1_HUMAN [view interactions] High throughput no yes
MRM1_HUMAN [view interactions] High throughput no no
SPG21_HUMAN [view interactions] High throughput no yes
STAR4_HUMAN [view interactions] High throughput no yes
RBFA_HUMAN [view interactions] High throughput no yes
THAP4_HUMAN [view interactions] High throughput no yes
SMG9_HUMAN [view interactions] High throughput no yes
WDFY2_HUMAN [view interactions] High throughput no no
PNKP_HUMAN [view interactions] High throughput no yes
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
CFTR_HUMAN [view interactions] High throughput no no
NDRG4_HUMAN [view interactions] High throughput no no
LNP_HUMAN [view interactions] High throughput no yes
PITC1_HUMAN [view interactions] High throughput no yes
WIPI2_HUMAN [view interactions] High throughput no yes
SSX5_HUMAN [view interactions] High throughput no no
PBX3_HUMAN [view interactions] High throughput no yes
GDNF_HUMAN [view interactions] High throughput no yes
MID49_HUMAN [view interactions] High throughput no yes
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
HAX1_HUMAN [view interactions] High throughput no no
BOREA_HUMAN [view interactions] High throughput no yes
DGUOK_HUMAN [view interactions] High throughput no yes
KTU_HUMAN [view interactions] High throughput no yes
S35B2_HUMAN [view interactions] High throughput no no
TMTC4_HUMAN [view interactions] High throughput no yes
ERD23_HUMAN [view interactions] High throughput no yes
JIP4_HUMAN [view interactions] High throughput no yes
MBOA7_HUMAN [view interactions] High throughput no no
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS4_HUMAN [view interactions] High throughput no yes
BSCL2_HUMAN [view interactions] High throughput no yes
MTCH1_HUMAN [view entry] [view interactions] High throughput yes yes
GPM6A_HUMAN [view entry] [view interactions] High throughput yes no
PARL_HUMAN [view interactions] High throughput no yes
LPAR1_HUMAN [view entry] [view interactions] High throughput yes no
CLN3_HUMAN [view interactions] High throughput no no
AOFB_HUMAN [view entry] [view interactions] High throughput yes yes
DHC24_HUMAN [view interactions] High throughput no yes
S27A1_HUMAN [view entry] [view interactions] High throughput yes no
PTSS2_HUMAN [view interactions] High throughput no yes
EXTL3_HUMAN [view interactions] High throughput no yes
GPAT4_HUMAN [view interactions] High throughput no yes
TMCO1_HUMAN [view interactions] High throughput no yes
SPG7_HUMAN [view interactions] High throughput no no
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
HIP1R_HUMAN [view entry] [view interactions] High throughput yes yes
S61A2_HUMAN [view interactions] High throughput no no
SURF1_HUMAN [view interactions] High throughput no yes
NCTR1_HUMAN [view interactions] High throughput no no
MACOI_HUMAN [view interactions] High throughput no no
LRC15_HUMAN [view interactions] High throughput no no
ORNT1_HUMAN [view interactions] High throughput no yes
VSIG8_HUMAN [view interactions] High throughput no no
SNH28_HUMAN [view interactions] High throughput no no
HYAS3_HUMAN [view interactions] High throughput no no
FDFT_HUMAN [view interactions] High throughput no yes
PMGT1_HUMAN [view interactions] High throughput no yes
PCAT2_HUMAN [view interactions] High throughput no yes
ALG11_HUMAN [view interactions] High throughput no yes
SRPRA_HUMAN [view interactions] High throughput no no
DHR13_HUMAN [view interactions] High throughput no yes
B3GA3_HUMAN [view entry] [view interactions] High throughput yes yes
MTX3_HUMAN [view interactions] High throughput no yes
NDUF4_HUMAN [view interactions] High throughput no yes
ECM29_HUMAN [view interactions] High throughput no no
SFXN2_HUMAN [view interactions] High throughput no no
S10A3_HUMAN [view interactions] High throughput no no
HPHL1_HUMAN [view interactions] High throughput no no
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
SYRM_HUMAN [view interactions] High throughput no yes
LBR_HUMAN [view interactions] High throughput no yes