GLPK_HUMAN
Evidence for PS localization
Functions
Key enzyme in the regulation of glycerol uptake and metabolism. [View more on UniProt]
Protein features
Binary interactions with known binding regions
Interacting region for partners were not defined.
Network
Isoforms
Disease-causing germline mutations
No data found.
Linear motifs
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Fingerprint
Molecular function
| Term | Name | % | Distance from the top of the tree | Annotated in GLPK_HUMAN |
|---|---|---|---|---|
| GO:0043169 | cation binding | 28.0000 | 4 | no |
| GO:0046872 | metal ion binding | 24.0000 | 5 | no |
| GO:0000166 | nucleotide binding | 16.0000 | 4 | yes |
| GO:0043168 | anion binding | 16.0000 | 4 | yes |
| GO:0017076 | purine nucleotide binding | 12.0000 | 5 | yes |
| GO:0032555 | purine ribonucleotide binding | 12.0000 | 4 | yes |
| GO:0035639 | purine ribonucleoside triphosphate binding | 12.0000 | 4 | yes |
| GO:0005524 | ATP binding | 8.0000 | 5 | yes |
| GO:0016301 | kinase activity | 8.0000 | 4 | yes |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 8.0000 | 4 | yes |
| GO:0030554 | adenyl nucleotide binding | 8.0000 | 6 | yes |
| GO:0032559 | adenyl ribonucleotide binding | 8.0000 | 5 | yes |
Biological process
| Term | Name | % | Distance from top the of the tree | Annotated in GLPK_HUMAN |
|---|---|---|---|---|
| GO:0048522 | positive regulation of cellular process | 48.0000 | 4 | no |
| GO:0060255 | regulation of macromolecule metabolic process | 44.0000 | 4 | no |
| GO:0006996 | organelle organization | 40.0000 | 4 | no |
| GO:0009893 | positive regulation of metabolic process | 40.0000 | 4 | no |
| GO:0031323 | regulation of cellular metabolic process | 40.0000 | 4 | no |
| GO:0051049 | regulation of transport | 40.0000 | 4 | no |
| GO:0010604 | positive regulation of macromolecule metabolic process | 36.0000 | 5 | no |
| GO:0010646 | regulation of cell communication | 36.0000 | 4 | no |
| GO:0042981 | regulation of apoptotic process | 36.0000 | 5 | no |
| GO:0043067 | regulation of programmed cell death | 36.0000 | 4 | no |
| GO:0048523 | negative regulation of cellular process | 36.0000 | 4 | no |
| GO:0051128 | regulation of cellular component organization | 36.0000 | 4 | no |
| GO:0051246 | regulation of protein metabolic process | 36.0000 | 5 | no |
| GO:0080090 | regulation of primary metabolic process | 36.0000 | 4 | no |
| GO:0008104 | protein localization | 32.0000 | 4 | no |
| GO:0009966 | regulation of signal transduction | 32.0000 | 4 | no |
| GO:0007005 | mitochondrion organization | 28.0000 | 5 | no |
| GO:0009892 | negative regulation of metabolic process | 28.0000 | 4 | no |
| GO:0031324 | negative regulation of cellular metabolic process | 28.0000 | 5 | no |
| GO:0033365 | protein localization to organelle | 28.0000 | 5 | no |
| GO:0048584 | positive regulation of response to stimulus | 28.0000 | 4 | no |
| GO:0051247 | positive regulation of protein metabolic process | 28.0000 | 6 | no |
| GO:0006915 | apoptotic process | 28.0000 | 4 | no |
| GO:0031325 | positive regulation of cellular metabolic process | 28.0000 | 5 | no |
| GO:0061024 | membrane organization | 28.0000 | 4 | no |
| GO:0019220 | regulation of phosphate metabolic process | 24.0000 | 6 | no |
| GO:0032880 | regulation of protein localization | 24.0000 | 5 | no |
| GO:0033043 | regulation of organelle organization | 24.0000 | 5 | no |
| GO:0051174 | regulation of phosphorus metabolic process | 24.0000 | 5 | no |
| GO:0060341 | regulation of cellular localization | 24.0000 | 4 | no |
| GO:0070585 | protein localization to mitochondrion | 24.0000 | 6 | no |
| GO:0007006 | mitochondrial membrane organization | 24.0000 | 5 | no |
| GO:0071702 | organic substance transport | 24.0000 | 4 | no |
| GO:0071705 | nitrogen compound transport | 24.0000 | 4 | no |
| GO:0009894 | regulation of catabolic process | 24.0000 | 4 | no |
| GO:0009889 | regulation of biosynthetic process | 24.0000 | 4 | no |
| GO:0010468 | regulation of gene expression | 24.0000 | 6 | no |
| GO:0010556 | regulation of macromolecule biosynthetic process | 24.0000 | 5 | no |
| GO:0031326 | regulation of cellular biosynthetic process | 24.0000 | 5 | no |
| GO:0019752 | carboxylic acid metabolic process | 16.0000 | 5 | yes |
| GO:0043436 | oxoacid metabolic process | 16.0000 | 4 | yes |
| GO:0006796 | phosphate-containing compound metabolic process | 12.0000 | 4 | yes |
| GO:1901566 | organonitrogen compound biosynthetic process | 12.0000 | 4 | yes |
| GO:0006638 | neutral lipid metabolic process | 8.0000 | 4 | yes |
| GO:0016053 | organic acid biosynthetic process | 8.0000 | 4 | yes |
| GO:0046394 | carboxylic acid biosynthetic process | 8.0000 | 5 | yes |
Disease
No data found.
All partners
| Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
|---|---|---|---|---|
| COX20_HUMAN | [view interactions] | High throughput | no | yes |
| WBP1_HUMAN | [view interactions] | High throughput | no | yes |
| ERGI3_HUMAN | [view interactions] | High throughput | no | yes |
| UBIP1_HUMAN | [view interactions] | High throughput | no | no |
| S22A6_HUMAN | [view interactions] | High throughput | no | no |
| PMEL_HUMAN | [view interactions] | High throughput | no | no |
| SNH28_HUMAN | [view interactions] | High throughput | no | no |
| SC6A4_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| GTR9_HUMAN | [view interactions] | High throughput | no | no |
| MAGA8_HUMAN | [view interactions] | High throughput | no | no |
| SC5A6_HUMAN | [view interactions] | High throughput | no | no |
| HUMMR_HUMAN | [view interactions] | High throughput | no | yes |
| GLPK2_HUMAN | [view interactions] | High throughput | no | no |
| MALL_HUMAN | [view interactions] | High throughput | no | no |
| NC2B_HUMAN | [view interactions] | High throughput | no | yes |
| MTLR_HUMAN | [view interactions] | High throughput | no | no |
| STUM_HUMAN | [view interactions] | High throughput | no | no |
| S22A8_HUMAN | [view interactions] | High throughput | no | no |
| SV2A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTH2R_HUMAN | [view interactions] | High throughput | no | no |
| SO1B3_HUMAN | [view interactions] | High throughput | no | no |
| CKLF8_HUMAN | [view interactions] | High throughput | no | yes |
| NRP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| BASI_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| VDAC1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| CCNF_HUMAN | [view interactions] | High throughput | no | no |
| ST1E1_HUMAN | [view interactions] | High throughput | no | no |
| ELAV2_HUMAN | [view interactions] | High throughput | no | yes |
| AKAP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| EXD2_HUMAN | [view interactions] | High throughput | no | yes |
| FBXL4_HUMAN | [view interactions] | High throughput | no | yes |
| FIS1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FKBP8_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MARH5_HUMAN | [view interactions] | High throughput | no | no |
| MAVS_HUMAN | [view interactions] | High throughput | no | yes |
| MTCH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MTCH2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| PTN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MIRO2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RMD3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| S2546_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| AIFM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| RFA1_HUMAN | [view interactions] | High throughput | no | yes |
| RFA2_HUMAN | [view interactions] | High throughput | no | yes |
| RFA3_HUMAN | [view interactions] | High throughput | no | yes |
| SAMP_HUMAN | [view interactions] | High throughput | no | no |
| AOXA_HUMAN | [view interactions] | High throughput | no | no |
| CP3A4_HUMAN | [view interactions] | High throughput | no | no |
| IF4G1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| GPDA_HUMAN | [view interactions] | High throughput | no | yes |
| NR4A1_HUMAN | [view interactions] | High throughput | no | yes |
| IPO13_HUMAN | [view interactions] | High throughput | no | yes |
| RXRA_HUMAN | [view interactions] | High throughput | no | yes |
| FBX28_HUMAN | [view interactions] | High throughput | no | yes |
| OPLA_HUMAN | [view interactions] | High throughput | no | no |
| CLP1L_HUMAN | [view interactions] | High throughput | no | yes |
| PDCD1_HUMAN | [view interactions] | High throughput | no | yes |
| CD70_HUMAN | [view interactions] | High throughput | no | no |
| VSIG4_HUMAN | [view interactions] | High throughput | no | no |
| APJ_HUMAN | [view interactions] | High throughput | no | yes |
| I13R2_HUMAN | [view interactions] | High throughput | no | no |
| GTR12_HUMAN | [view interactions] | High throughput | no | yes |
| FPR2_HUMAN | [view interactions] | High throughput | no | yes |
| SC5A8_HUMAN | [view interactions] | High throughput | no | no |
| SYPH_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TNFA_HUMAN | [view interactions] | High throughput | no | no |
| ACM4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| MUC20_HUMAN | [view interactions] | High throughput | no | no |
| VSIG1_HUMAN | [view interactions] | High throughput | no | no |
| PI2R_HUMAN | [view interactions] | High throughput | no | no |
| MFD4A_HUMAN | [view interactions] | High throughput | no | yes |
| GHITM_HUMAN | [view interactions] | High throughput | no | yes |
| SG1D2_HUMAN | [view interactions] | High throughput | no | no |
| APOD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| ZA2G_HUMAN | [view interactions] | High throughput | no | no |
| HBB_HUMAN | [view interactions] | High throughput | no | no |
| GLPK3_HUMAN | [view interactions] | High throughput | no | no |
| VSIG8_HUMAN | [view interactions] | High throughput | no | no |
| RSPRY_HUMAN | [view interactions] | High throughput | no | yes |
| FCG3A_HUMAN | [view interactions] | High throughput | no | no |
| OCAD1_HUMAN | [view interactions] | High throughput | no | yes |
| SYUA_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| FOXS1_HUMAN | [view interactions] | High throughput | no | yes |
| MGST3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| TOM20_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| FHI2B_HUMAN | [view interactions] | High throughput | no | yes |
| CFTR_HUMAN | [view interactions] | High throughput | no | no |
| UBC_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
| RIC3_HUMAN | [view interactions] | High throughput | no | yes |
| FCG3B_HUMAN | [view interactions] | High throughput | no | no |
| C1QB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
| SGCZ_HUMAN | [view interactions] | High throughput | no | no |
| SACA1_HUMAN | [view interactions] | High throughput | no | no |
| SLAF1_HUMAN | [view interactions] | High throughput | no | no |