Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

VDAC1_HUMAN

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed, PubMed, PubMed, PubMed). Binds various signaling molecules, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (PubMed). In depolarized mitochondria, acts downstream of PRKN and PINK1 to promote mitophagy or prevent apoptosis; polyubiquitination by PRKN promotes mitophagy, while monoubiquitination by PRKN decreases mitochondrial calcium influx which ultimately inhibits apoptosis (PubMed). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed, PubMed). May mediate ATP export from cells (PubMed). [View more on UniProt]

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No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in VDAC1_HUMAN
GO:0017076 purine nucleotide binding 24.1071 4 no
GO:0046872 metal ion binding 24.1071 4 no
GO:0032555 purine ribonucleotide binding 22.7679 4 no
GO:0035639 purine ribonucleoside triphosphate binding 22.3214 4 no
GO:0003723 RNA binding 21.4286 4 no
GO:0019900 kinase binding 12.9464 4 yes
GO:0019901 protein kinase binding 11.1607 5 yes
GO:0008509 anion transmembrane transporter activity 6.6964 4 yes
GO:0015267 channel activity 4.9107 4 yes
GO:0005216 ion channel activity 4.0179 4 yes
GO:0022836 gated channel activity 3.1250 5 yes
GO:0005244 voltage-gated ion channel activity 2.6786 4 yes
GO:0022829 wide pore channel activity 2.6786 5 yes
GO:0022832 voltage-gated channel activity 2.6786 6 yes
GO:0015103 inorganic anion transmembrane transporter activity 2.2321 4 yes
GO:0015288 porin activity 2.2321 6 yes
GO:0015485 cholesterol binding 2.2321 4 yes
GO:0032934 sterol binding 2.2321 4 yes
GO:0005253 anion channel activity 1.7857 5 yes
GO:0008308 voltage-gated anion channel activity 1.7857 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in VDAC1_HUMAN
GO:0006996 organelle organization 39.2857 4 no
GO:0048522 positive regulation of cellular process 38.8393 4 yes
GO:0060255 regulation of macromolecule metabolic process 34.8214 4 no
GO:0048523 negative regulation of cellular process 34.3750 4 yes
GO:0031323 regulation of cellular metabolic process 33.9286 4 yes
GO:0080090 regulation of primary metabolic process 33.4821 4 no
GO:0022607 cellular component assembly 32.5893 4 no
GO:0051171 regulation of nitrogen compound metabolic process 32.1429 4 no
GO:0051128 regulation of cellular component organization 30.8036 4 yes
GO:0008104 protein localization 29.4643 4 no
GO:0009893 positive regulation of metabolic process 27.6786 4 yes
GO:0071702 organic substance transport 27.6786 4 no
GO:0010646 regulation of cell communication 26.7857 4 no
GO:0071705 nitrogen compound transport 26.3393 4 no
GO:0051246 regulation of protein metabolic process 25.8929 5 no
GO:0010468 regulation of gene expression 23.6607 5 no
GO:0009966 regulation of signal transduction 23.6607 4 no
GO:0010604 positive regulation of macromolecule metabolic process 23.2143 5 no
GO:0051049 regulation of transport 22.7679 4 yes
GO:0010941 regulation of cell death 22.3214 4 yes
GO:0009892 negative regulation of metabolic process 21.4286 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 20.9821 5 no
GO:0043067 regulation of programmed cell death 20.5357 5 yes
GO:0015031 protein transport 20.5357 4 no
GO:0031325 positive regulation of cellular metabolic process 19.6429 5 yes
GO:0042981 regulation of apoptotic process 19.6429 6 yes
GO:0033043 regulation of organelle organization 18.7500 5 yes
GO:0009894 regulation of catabolic process 17.4107 4 yes
GO:0060548 negative regulation of cell death 16.0714 5 yes
GO:0051130 positive regulation of cellular component organization 15.6250 5 yes
GO:0006811 ion transport 15.1786 4 yes
GO:0043069 negative regulation of programmed cell death 14.7321 6 yes
GO:0031329 regulation of cellular catabolic process 14.2857 5 yes
GO:0043066 negative regulation of apoptotic process 13.8393 7 yes
GO:0006915 apoptotic process 11.6071 4 yes
GO:0010638 positive regulation of organelle organization 11.6071 6 yes
GO:0043269 regulation of ion transport 11.1607 5 yes
GO:0019752 carboxylic acid metabolic process 10.7143 5 yes
GO:0043436 oxoacid metabolic process 10.7143 4 yes
GO:0010506 regulation of autophagy 9.8214 6 yes
GO:0009896 positive regulation of catabolic process 9.3750 5 yes
GO:0034762 regulation of transmembrane transport 9.3750 4 yes
GO:0032787 monocarboxylic acid metabolic process 8.9286 6 yes
GO:0034765 regulation of ion transmembrane transport 8.9286 5 yes
GO:1904062 regulation of cation transmembrane transport 7.5893 6 yes
GO:0006820 anion transport 7.1429 5 yes
GO:0010821 regulation of mitochondrion organization 7.1429 6 yes
GO:0031331 positive regulation of cellular catabolic process 7.1429 6 yes
GO:0051051 negative regulation of transport 7.1429 4 yes
GO:0010959 regulation of metal ion transport 6.6964 6 yes
GO:0016241 regulation of macroautophagy 6.6964 7 yes
GO:0010822 positive regulation of mitochondrion organization 5.3571 7 yes
GO:0006090 pyruvate metabolic process 4.9107 7 yes
GO:0010508 positive regulation of autophagy 4.4643 7 yes
GO:0051924 regulation of calcium ion transport 4.4643 7 yes
GO:1903169 regulation of calcium ion transmembrane transport 4.0179 7 yes
GO:0016239 positive regulation of macroautophagy 3.5714 8 yes
GO:0043271 negative regulation of ion transport 3.1250 5 yes
GO:1903146 regulation of autophagy of mitochondrion 3.1250 7 yes
GO:1903599 positive regulation of autophagy of mitochondrion 3.1250 8 yes
GO:0034763 negative regulation of transmembrane transport 2.6786 5 yes
GO:0034766 negative regulation of ion transmembrane transport 2.6786 6 yes
GO:1904063 negative regulation of cation transmembrane transport 2.6786 7 yes
GO:0030855 epithelial cell differentiation 2.2321 4 yes
GO:0051926 negative regulation of calcium ion transport 1.7857 6 yes
GO:1901524 regulation of mitophagy 1.7857 8 yes
GO:1901526 positive regulation of mitophagy 1.7857 9 yes
GO:1903170 negative regulation of calcium ion transmembrane transport 1.7857 7 yes
GO:0110097 regulation of calcium import into the mitochondrion 0.8929 8 yes
GO:0110099 negative regulation of calcium import into the mitochondrion 0.8929 8 yes

Disease

Term Name % Distance from top the of the tree Annotated in VDAC1_HUMAN
DOID:331 central nervous system disease 3.1250 3 no
DOID:1289 neurodegenerative disease 2.2321 4 no
DOID:10595 Charcot-Marie-Tooth disease 1.3393 6 no
DOID:440 neuromuscular disease 1.3393 5 no
DOID:574 peripheral nervous system disease 1.3393 3 no
DOID:870 neuropathy 1.3393 4 no
DOID:0050700 cardiomyopathy 1.3393 4 no
DOID:0060036 intrinsic cardiomyopathy 1.3393 5 no
DOID:114 heart disease 1.3393 3 no
DOID:12930 dilated cardiomyopathy 1.3393 6 no
DOID:0050890 synucleinopathy 1.3393 5 no
DOID:14330 Parkinsons disease 1.3393 6 no
DOID:936 brain disease 0.8929 4 no
DOID:0080000 muscular disease 0.8929 3 no
DOID:423 myopathy 0.8929 5 no
DOID:66 muscle tissue disease 0.8929 4 no
DOID:0050539 Charcot-Marie-Tooth disease type 2 0.8929 7 no
DOID:0060892 late onset Parkinsons disease 0.8929 7 no
DOID:0060894 early-onset Parkinsons disease 0.8929 7 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
SQSTM_HUMAN [view interactions] Low throughput no yes
TOM20_HUMAN [view entry] [view interactions] Low throughput yes yes
MCL1_HUMAN [view interactions] Low throughput no yes
TPA_HUMAN [view entry] [view interactions] Low throughput yes no
RNF31_HUMAN [view interactions] Low throughput no yes
MK01_HUMAN [view entry] [view interactions] Low throughput yes yes
UBP19_HUMAN [view interactions] Low throughput no no
CYC_HUMAN [view entry] [view interactions] Low throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] Low throughput yes yes
PPIF_HUMAN [view interactions] Low throughput no no
KPCE_HUMAN [view entry] [view interactions] Low throughput yes yes
MK03_HUMAN [view entry] [view interactions] Low throughput yes yes
BCL2_HUMAN [view interactions] Low throughput no no
B2CL1_HUMAN [view interactions] Low throughput no yes
HXK2_HUMAN [view interactions] Low throughput no yes
GRP75_HUMAN [view entry] [view interactions] Low throughput yes yes
ITPR1_HUMAN [view entry] [view interactions] Low throughput yes yes
NDUV1_HUMAN [view entry] [view interactions] Low throughput yes yes
GELS_HUMAN [view entry] [view interactions] Low throughput yes no
ATF2_HUMAN [view interactions] Low throughput no yes
ADT3_HUMAN [view entry] [view interactions] Low throughput yes yes
LRRK2_HUMAN [view interactions] Low throughput no yes
SIAH2_HUMAN [view interactions] Low throughput no no
TRAF2_HUMAN [view interactions] Low throughput no yes
IKKB_HUMAN [view interactions] Low throughput no yes
PEMT_HUMAN [view interactions] Low throughput no yes
KLK1_HUMAN [view interactions] Low throughput no yes
ITPR3_HUMAN [view interactions] Low throughput no yes
KLH40_HUMAN [view interactions] Low throughput no no
DYLT1_HUMAN [view interactions] Low throughput no no
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
B2L11_HUMAN [view interactions] Low throughput no yes
BOP_HUMAN [view interactions] Low throughput no no
CAV1_HUMAN [view interactions] Low throughput no no
PRKN_HUMAN [view entry] [view interactions] Low throughput yes yes
TBA1B_HUMAN [view entry] [view interactions] Low throughput yes yes
BAK_HUMAN [view interactions] Low throughput no no
BAX_HUMAN [view interactions] Low throughput no yes
HXK1_HUMAN [view entry] [view interactions] Low throughput yes yes
VDAC1_HUMAN [view entry] [view interactions] Low throughput yes yes
TSPO_HUMAN [view interactions] Low throughput no yes
F162A_HUMAN [view interactions] Low throughput no yes
NEDD4_HUMAN [view entry] [view interactions] Low throughput yes yes
BAP31_HUMAN [view interactions] Low throughput no yes
PARK7_HUMAN [view entry] [view interactions] Low throughput yes yes
ETFA_HUMAN [view interactions] High throughput no yes
AT1B3_HUMAN [view interactions] High throughput no yes
LDHA_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5J_HUMAN [view interactions] High throughput no yes
SYDC_HUMAN [view interactions] High throughput no yes
ACACA_HUMAN [view entry] [view interactions] High throughput yes yes
CLCC1_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
RN139_HUMAN [view interactions] High throughput no yes
H2AV_HUMAN [view interactions] High throughput no yes
BAG5_HUMAN [view entry] [view interactions] High throughput yes no
SF3B6_HUMAN [view interactions] High throughput no yes
ANDR_HUMAN [view interactions] High throughput no no
NDUV2_HUMAN [view entry] [view interactions] High throughput yes yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
HNRDL_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
SURF6_HUMAN [view interactions] High throughput no yes
MCA3_HUMAN [view interactions] High throughput no yes
ZBTB2_HUMAN [view interactions] High throughput no yes
SPIN1_HUMAN [view interactions] High throughput no no
PGAM2_HUMAN [view entry] [view interactions] High throughput yes no
RUVB1_HUMAN [view interactions] High throughput no yes
GPR35_HUMAN [view interactions] High throughput no no
ECHB_HUMAN [view entry] [view interactions] High throughput yes yes
ZFYV1_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
NRP1_HUMAN [view entry] [view interactions] High throughput yes yes
NOP58_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
PABP1_HUMAN [view entry] [view interactions] High throughput yes yes
KCNA3_HUMAN [view entry] [view interactions] High throughput yes no
QCR1_HUMAN [view entry] [view interactions] High throughput yes yes
SAM50_HUMAN [view entry] [view interactions] High throughput yes yes
ATPO_HUMAN [view interactions] High throughput no yes
CALD1_HUMAN [view entry] [view interactions] High throughput yes no
RCN2_HUMAN [view interactions] High throughput no yes
NB5R3_HUMAN [view interactions] High throughput no yes
TPM3_HUMAN [view entry] [view interactions] High throughput yes yes
ELOV1_HUMAN [view interactions] High throughput no yes
SSBP_HUMAN [view entry] [view interactions] High throughput yes yes
FKBP8_HUMAN [view entry] [view interactions] High throughput yes yes
NOP56_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
ATPG_HUMAN [view interactions] High throughput no yes
KAPCA_HUMAN [view entry] [view interactions] High throughput yes yes
PI51C_HUMAN [view entry] [view interactions] High throughput yes yes
RAB14_HUMAN [view entry] [view interactions] High throughput yes yes
PROF1_HUMAN [view entry] [view interactions] High throughput yes yes
RAB1A_HUMAN [view entry] [view interactions] High throughput yes yes
MIC60_HUMAN [view entry] [view interactions] High throughput yes yes
RAB1B_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS1_HUMAN [view entry] [view interactions] High throughput yes no
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
ATPK_HUMAN [view interactions] High throughput no yes
SAR1B_HUMAN [view interactions] High throughput no yes
ATD3A_HUMAN [view entry] [view interactions] High throughput yes yes
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
SSRD_HUMAN [view interactions] High throughput no yes
GLPK_HUMAN [view entry] [view interactions] High throughput yes no
PRDX3_HUMAN [view interactions] High throughput no yes
NDKB_HUMAN [view entry] [view interactions] High throughput yes yes
IMDH2_HUMAN [view interactions] High throughput no yes
RSPRY_HUMAN [view interactions] High throughput no yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
PLCE_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
SERPH_HUMAN [view interactions] High throughput no no
ATAD1_HUMAN [view entry] [view interactions] High throughput yes yes
RNPS1_HUMAN [view interactions] High throughput no yes
FAS_HUMAN [view entry] [view interactions] High throughput yes no
CALX_HUMAN [view entry] [view interactions] High throughput yes yes
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
FBRL_HUMAN [view interactions] High throughput no yes
PRDX6_HUMAN [view entry] [view interactions] High throughput yes yes
DKC1_HUMAN [view interactions] High throughput no yes
RL30_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
MPCP_HUMAN [view entry] [view interactions] High throughput yes no
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
RL40_HUMAN [view entry] [view interactions] High throughput yes yes
RL28_HUMAN [view entry] [view interactions] High throughput yes yes
SF01_HUMAN [view interactions] High throughput no yes
ILF2_HUMAN [view interactions] High throughput no yes
SFXN3_HUMAN [view entry] [view interactions] High throughput yes yes
RMXL2_HUMAN [view interactions] High throughput no no
TIAR_HUMAN [view interactions] High throughput no no
H10_HUMAN [view interactions] High throughput no yes
UBAP2_HUMAN [view interactions] High throughput no yes
EMD_HUMAN [view interactions] High throughput no yes
SUGP1_HUMAN [view interactions] High throughput no yes
RL35_HUMAN [view entry] [view interactions] High throughput yes yes
FACE1_HUMAN [view interactions] High throughput no yes
RL12_HUMAN [view entry] [view interactions] High throughput yes yes
UFM1_HUMAN [view interactions] High throughput no yes
ODPB_HUMAN [view entry] [view interactions] High throughput yes yes
THIM_HUMAN [view interactions] High throughput no yes
STML2_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
COX41_HUMAN [view entry] [view interactions] High throughput yes yes
MGT4B_HUMAN [view interactions] High throughput no no
XRCC5_HUMAN [view interactions] High throughput no yes
SSDH_HUMAN [view entry] [view interactions] High throughput yes yes
RL27_HUMAN [view entry] [view interactions] High throughput yes yes
ATPA_HUMAN [view interactions] High throughput no yes
MOB2_HUMAN [view interactions] High throughput no no
ATPB_HUMAN [view interactions] High throughput no yes
ERH_HUMAN [view interactions] High throughput no yes
ATPD_HUMAN [view interactions] High throughput no yes
ATP5H_HUMAN [view interactions] High throughput no yes
ATP5I_HUMAN [view interactions] High throughput no yes
LMNB1_HUMAN [view entry] [view interactions] High throughput yes yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
RL36_HUMAN [view entry] [view interactions] High throughput yes yes
BAP29_HUMAN [view interactions] High throughput no yes
SAP18_HUMAN [view interactions] High throughput no yes
CISD1_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
CISD2_HUMAN [view interactions] High throughput no yes
ARF1_HUMAN [view entry] [view interactions] High throughput yes yes
CLH1_HUMAN [view entry] [view interactions] High throughput yes yes
SCYL2_HUMAN [view interactions] High throughput no yes
GPX4_HUMAN [view entry] [view interactions] High throughput yes no
H1X_HUMAN [view interactions] High throughput no yes
MAGT1_HUMAN [view interactions] High throughput no yes
NDUA8_HUMAN [view entry] [view interactions] High throughput yes yes
PPIA_HUMAN [view entry] [view interactions] High throughput yes yes
NDUA9_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
PHB2_HUMAN [view entry] [view interactions] High throughput yes yes
H2B1C_HUMAN [view interactions] High throughput no yes
SGPL1_HUMAN [view interactions] High throughput no yes
BAF_HUMAN [view entry] [view interactions] High throughput yes yes
SSRG_HUMAN [view interactions] High throughput no yes
CX7A2_HUMAN [view interactions] High throughput no no
STX12_HUMAN [view entry] [view interactions] High throughput yes yes
ADT2_HUMAN [view entry] [view interactions] High throughput yes yes
TOM40_HUMAN [view interactions] High throughput no yes
QCR2_HUMAN [view entry] [view interactions] High throughput yes yes
MRP1_HUMAN [view interactions] High throughput no no
NDUA5_HUMAN [view entry] [view interactions] High throughput yes yes
MRP3_HUMAN [view interactions] High throughput no no
SFXN1_HUMAN [view entry] [view interactions] High throughput yes yes
ACADM_HUMAN [view interactions] High throughput no yes
RUXGL_HUMAN [view interactions] High throughput no no
AQP9_HUMAN [view interactions] High throughput no no
MIC19_HUMAN [view entry] [view interactions] High throughput yes yes
AT1A2_HUMAN [view entry] [view interactions] High throughput yes yes
TPM1_HUMAN [view entry] [view interactions] High throughput yes no
AT1A3_HUMAN [view entry] [view interactions] High throughput yes no
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
AT1B1_HUMAN [view entry] [view interactions] High throughput yes no
H2A1B_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
VATA_HUMAN [view entry] [view interactions] High throughput yes yes
TOM22_HUMAN [view interactions] High throughput no yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
THIO_HUMAN [view interactions] High throughput no yes
MTCH1_HUMAN [view entry] [view interactions] High throughput yes yes
ML12A_HUMAN [view interactions] High throughput no no
MTCH2_HUMAN [view entry] [view interactions] High throughput yes yes
XRCC6_HUMAN [view interactions] High throughput no yes
NDUB4_HUMAN [view entry] [view interactions] High throughput yes yes
BOLA2_HUMAN [view interactions] High throughput no yes
NDUS4_HUMAN [view interactions] High throughput no yes
PPM1B_HUMAN [view interactions] High throughput no yes
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
CHTOP_HUMAN [view interactions] High throughput no yes
TECR_HUMAN [view interactions] High throughput no yes
DNJC9_HUMAN [view interactions] High throughput no yes
TMX1_HUMAN [view interactions] High throughput no no
DCD_HUMAN [view interactions] High throughput no no
QCR7_HUMAN [view entry] [view interactions] High throughput yes yes
RNPL1_HUMAN [view interactions] High throughput no no
DHCR7_HUMAN [view interactions] High throughput no yes
NOL7_HUMAN [view interactions] High throughput no yes
BST2_HUMAN [view interactions] High throughput no yes
RAI14_HUMAN [view interactions] High throughput no yes
OCAD2_HUMAN [view interactions] High throughput no yes
RIF1_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
FLRT2_HUMAN [view interactions] High throughput no no
GBB2_HUMAN [view entry] [view interactions] High throughput yes yes
FA11_HUMAN [view interactions] High throughput no no
GBB1_HUMAN [view entry] [view interactions] High throughput yes yes
YG046_HUMAN [view interactions] High throughput no no
MCAT_HUMAN [view interactions] High throughput no yes
PCSK6_HUMAN [view interactions] High throughput no yes
SCPDL_HUMAN [view entry] [view interactions] High throughput yes yes
GDIR3_HUMAN [view interactions] High throughput no no
GBB4_HUMAN [view entry] [view interactions] High throughput yes yes
AK1BA_HUMAN [view interactions] High throughput no no
NJMU_HUMAN [view interactions] High throughput no yes
TM11F_HUMAN [view interactions] High throughput no no
SCRB1_HUMAN [view interactions] High throughput no no
DOC2A_HUMAN [view entry] [view interactions] High throughput yes no
CUL9_HUMAN [view interactions] High throughput no no
MLEC_HUMAN [view interactions] High throughput no no
SYUA_HUMAN [view entry] [view interactions] High throughput yes no
MYOF_HUMAN [view interactions] High throughput no yes
HD_HUMAN [view entry] [view interactions] High throughput yes yes
GALT2_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
MOGS_HUMAN [view interactions] High throughput no yes
MED20_HUMAN [view interactions] High throughput no no
RAB19_HUMAN [view interactions] High throughput no no
FXRD2_HUMAN [view interactions] High throughput no yes
DAD1_HUMAN [view entry] [view interactions] High throughput yes yes
UBAC2_HUMAN [view interactions] High throughput no yes
ATPMK_HUMAN [view interactions] High throughput no no
M3K7_HUMAN [view interactions] High throughput no yes
RAB5A_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK4_HUMAN [view interactions] High throughput no no
MEST_HUMAN [view interactions] High throughput no no
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
AT2A2_HUMAN [view entry] [view interactions] High throughput yes yes
MYLK4_HUMAN [view interactions] High throughput no no
COX7R_HUMAN [view entry] [view interactions] High throughput yes no
COQ8A_HUMAN [view interactions] High throughput no no
COX7C_HUMAN [view interactions] High throughput no yes
PAK6_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
LAT_HUMAN [view interactions] High throughput no no
ICAM1_HUMAN [view interactions] High throughput no no
KLF16_HUMAN [view interactions] High throughput no yes
NDUBA_HUMAN [view entry] [view interactions] High throughput yes yes
KLF8_HUMAN [view interactions] High throughput no no
NDUS2_HUMAN [view entry] [view interactions] High throughput yes yes
NDUS5_HUMAN [view interactions] High throughput no yes
PANK2_HUMAN [view interactions] High throughput no yes
NDUS8_HUMAN [view interactions] High throughput no yes
TRAF6_HUMAN [view interactions] High throughput no yes
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
CASP4_HUMAN [view interactions] High throughput no yes
EF1A1_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK2_HUMAN [view interactions] High throughput no yes
NDUB9_HUMAN [view entry] [view interactions] High throughput yes yes
CRCM_HUMAN [view interactions] High throughput no no
NIPS1_HUMAN [view entry] [view interactions] High throughput yes yes
IF6_HUMAN [view interactions] High throughput no yes
ODO1_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
CD166_HUMAN [view interactions] High throughput no no
TITIN_HUMAN [view interactions] High throughput no no
CKAP4_HUMAN [view entry] [view interactions] High throughput yes yes
CI163_HUMAN [view interactions] High throughput no no
MUC18_HUMAN [view interactions] High throughput no yes
GSTK1_HUMAN [view entry] [view interactions] High throughput yes yes
PLOD1_HUMAN [view interactions] High throughput no yes
GANAB_HUMAN [view interactions] High throughput no yes
RFTN1_HUMAN [view entry] [view interactions] High throughput yes no
FSCN1_HUMAN [view entry] [view interactions] High throughput yes yes
SEPT2_HUMAN [view interactions] High throughput no no
AATM_HUMAN [view entry] [view interactions] High throughput yes yes
SPTN1_HUMAN [view entry] [view interactions] High throughput yes yes
CBR1_HUMAN [view entry] [view interactions] High throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
IKKE_HUMAN [view interactions] High throughput no yes
TBB2A_HUMAN [view entry] [view interactions] High throughput yes yes
HLAB_HUMAN [view interactions] High throughput no yes
AT2B1_HUMAN [view entry] [view interactions] High throughput yes yes
SF3A1_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
KINH_HUMAN [view entry] [view interactions] High throughput yes no
ITAV_HUMAN [view interactions] High throughput no yes
NUDC_HUMAN [view interactions] High throughput no yes
PLOD3_HUMAN [view interactions] High throughput no yes
THIC_HUMAN [view interactions] High throughput no yes
ABLM2_HUMAN [view entry] [view interactions] High throughput yes yes
KCMA1_HUMAN [view entry] [view interactions] High throughput yes no
NOVA1_HUMAN [view interactions] High throughput no yes
OPHN1_HUMAN [view entry] [view interactions] High throughput yes yes
JUN_HUMAN [view interactions] High throughput no yes
PDLI5_HUMAN [view entry] [view interactions] High throughput yes no
AAKB1_HUMAN [view interactions] High throughput no yes
VGLU2_HUMAN [view interactions] High throughput no no
TOM70_HUMAN [view interactions] High throughput no yes
CX6B1_HUMAN [view entry] [view interactions] High throughput yes yes
VGLU1_HUMAN [view entry] [view interactions] High throughput yes no
PP1A_HUMAN [view entry] [view interactions] High throughput yes yes
KCRU_HUMAN [view entry] [view interactions] High throughput yes yes
CAV3_HUMAN [view interactions] High throughput no no
DYLT3_HUMAN [view interactions] High throughput no yes
CD177_HUMAN [view interactions] High throughput no no
TBA4A_HUMAN [view entry] [view interactions] High throughput yes yes
TX101_HUMAN [view interactions] High throughput no no
EWS_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
DPPA3_HUMAN [view interactions] High throughput no no
CNDD3_HUMAN [view interactions] High throughput no no
MTEF3_HUMAN [view interactions] High throughput no no
CSK2B_HUMAN [view entry] [view interactions] High throughput yes yes
OCAD1_HUMAN [view interactions] High throughput no yes
WLS_HUMAN [view entry] [view interactions] High throughput yes no
S2546_HUMAN [view entry] [view interactions] High throughput yes yes
GLUT4_HUMAN [view interactions] High throughput no no
AKAP1_HUMAN [view entry] [view interactions] High throughput yes yes
ACTB_HUMAN [view entry] [view interactions] High throughput yes no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
DHRS2_HUMAN [view interactions] High throughput no no
NAA40_HUMAN [view interactions] High throughput no no
ICT1_HUMAN [view interactions] High throughput no yes
STOM_HUMAN [view entry] [view interactions] High throughput yes yes
TMPS2_HUMAN [view interactions] High throughput no no
PAF1_HUMAN [view interactions] High throughput no yes
TOP3B_HUMAN [view interactions] High throughput no no
A2MG_HUMAN [view interactions] High throughput no yes
CATL1_HUMAN [view interactions] High throughput no yes
IFM1_HUMAN [view interactions] High throughput no no
MK06_HUMAN [view interactions] High throughput no yes
AMPN_HUMAN [view interactions] High throughput no no
RAB5C_HUMAN [view entry] [view interactions] High throughput yes yes
DPP4_HUMAN [view interactions] High throughput no no
RMD3_HUMAN [view interactions] High throughput no yes
IFM3_HUMAN [view interactions] High throughput no yes
MYO19_HUMAN [view interactions] High throughput no yes
PCNA_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
RAB7A_HUMAN [view entry] [view interactions] High throughput yes yes
ACAD9_HUMAN [view interactions] High throughput no yes
CLC4D_HUMAN [view interactions] High throughput no no
TM109_HUMAN [view interactions] High throughput no yes
TMPS4_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
PSN1_HUMAN [view entry] [view interactions] High throughput yes yes
CLC4E_HUMAN [view interactions] High throughput no no
MTX2_HUMAN [view entry] [view interactions] High throughput yes yes
PER2_HUMAN [view interactions] High throughput no yes
TMED2_HUMAN [view interactions] High throughput no yes
MGST3_HUMAN [view entry] [view interactions] High throughput yes yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
VAPA_HUMAN [view entry] [view interactions] High throughput yes yes
NECD_HUMAN [view interactions] High throughput no no
RAB2A_HUMAN [view entry] [view interactions] High throughput yes yes
MYC_HUMAN [view interactions] High throughput no yes
EMC5_HUMAN [view interactions] High throughput no yes
FGOP2_HUMAN [view interactions] High throughput no yes
INT14_HUMAN [view interactions] High throughput no yes
GOT1B_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
APOE_HUMAN [view entry] [view interactions] High throughput yes yes
CD4_HUMAN [view interactions] High throughput no no
AAPK1_HUMAN [view interactions] High throughput no no
HDAC5_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
CK068_HUMAN [view interactions] High throughput no yes
MET14_HUMAN [view interactions] High throughput no yes
HAUS3_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
SUMO2_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
SUMO3_HUMAN [view interactions] High throughput no yes
A4_HUMAN [view entry] [view interactions] High throughput yes yes
SIR7_HUMAN [view interactions] High throughput no yes
SH3L1_HUMAN [view interactions] High throughput no yes
CDK2_HUMAN [view interactions] High throughput no yes
CAV2_HUMAN [view interactions] High throughput no no
MDC1_HUMAN [view interactions] High throughput no yes
ZDHC5_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
FMNL1_HUMAN [view entry] [view interactions] High throughput yes no
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
CTBP1_HUMAN [view entry] [view interactions] High throughput yes yes
ASB14_HUMAN [view interactions] High throughput no no
VPS35_HUMAN [view entry] [view interactions] High throughput yes yes
ASB17_HUMAN [view interactions] High throughput no no
ZBT18_HUMAN [view interactions] High throughput no yes
SPRTN_HUMAN [view interactions] High throughput no yes
MOT11_HUMAN [view interactions] High throughput no no
MOV10_HUMAN [view interactions] High throughput no no
DCAF4_HUMAN [view interactions] High throughput no yes
NXF1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
ZG16B_HUMAN [view interactions] High throughput no no
HUTH_HUMAN [view interactions] High throughput no yes
VCAM1_HUMAN [view interactions] High throughput no no
PLIN3_HUMAN [view interactions] High throughput no yes
COX15_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
SOAT1_HUMAN [view interactions] High throughput no no
U2AF2_HUMAN [view interactions] High throughput no yes
COX2_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
PPM1A_HUMAN [view interactions] High throughput no yes
TADBP_HUMAN [view interactions] High throughput no yes
D19L1_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
TOP1_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
FILA2_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view interactions] High throughput no yes
H90B3_HUMAN [view interactions] High throughput no no
AAR2_HUMAN [view interactions] High throughput no no
SAFB2_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
IMB1_HUMAN [view entry] [view interactions] High throughput yes yes
CHD3_HUMAN [view interactions] High throughput no yes
OST48_HUMAN [view entry] [view interactions] High throughput yes yes
CHD4_HUMAN [view interactions] High throughput no yes
MYH11_HUMAN [view entry] [view interactions] High throughput yes no
SYLC_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
TOP2A_HUMAN [view interactions] High throughput no no
PPT1_HUMAN [view interactions] High throughput no yes
SYIC_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
RECQ4_HUMAN [view interactions] High throughput no yes
RTCB_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
SYEP_HUMAN [view interactions] High throughput no yes
GLP1R_HUMAN [view interactions] High throughput no no
HS904_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
COPE_HUMAN [view interactions] High throughput no yes
PSA3_HUMAN [view interactions] High throughput no no
HP1B3_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
TPIS_HUMAN [view entry] [view interactions] High throughput yes yes
FAF1_HUMAN [view interactions] High throughput no yes
HORN_HUMAN [view interactions] High throughput no no
TM41B_HUMAN [view interactions] High throughput no yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
TIA1_HUMAN [view interactions] High throughput no no
PERI_HUMAN [view entry] [view interactions] High throughput yes no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
LMNB2_HUMAN [view entry] [view interactions] High throughput yes yes
HG2A_HUMAN [view interactions] High throughput no yes
ECHA_HUMAN [view entry] [view interactions] High throughput yes yes
P2RY6_HUMAN [view interactions] High throughput no no
CMC2_HUMAN [view entry] [view interactions] High throughput yes yes
S15A3_HUMAN [view interactions] High throughput no yes
EF1G_HUMAN [view entry] [view interactions] High throughput yes yes
UN93B_HUMAN [view interactions] High throughput no yes
SP16H_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
SAFB1_HUMAN [view interactions] High throughput no yes
LMBRL_HUMAN [view interactions] High throughput no no
RM12_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
CDK1_HUMAN [view interactions] High throughput no no
PINK1_HUMAN [view interactions] High throughput no yes
DDX21_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
CBX1_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
TR150_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
RPN2_HUMAN [view entry] [view interactions] High throughput yes yes
PMEPA_HUMAN [view interactions] High throughput no no
LA_HUMAN [view interactions] High throughput no yes
VAV_HUMAN [view interactions] High throughput no no
AAAT_HUMAN [view interactions] High throughput no no
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
RL1D1_HUMAN [view interactions] High throughput no yes
ANLN_HUMAN [view interactions] High throughput no yes
NP1L1_HUMAN [view entry] [view interactions] High throughput yes yes
CHM4C_HUMAN [view interactions] High throughput no yes
BASI_HUMAN [view entry] [view interactions] High throughput yes no
ECT2_HUMAN [view interactions] High throughput no no
ERLN1_HUMAN [view entry] [view interactions] High throughput yes yes
KIF14_HUMAN [view interactions] High throughput no no
KCRB_HUMAN [view entry] [view interactions] High throughput yes no
KI20A_HUMAN [view interactions] High throughput no yes
4F2_HUMAN [view entry] [view interactions] High throughput yes no
PRC1_HUMAN [view interactions] High throughput no yes
ERLN2_HUMAN [view entry] [view interactions] High throughput yes yes
MD2L2_HUMAN [view interactions] High throughput no yes
CBX3_HUMAN [view interactions] High throughput no yes
TKT_HUMAN [view entry] [view interactions] High throughput yes yes
NMRL1_HUMAN [view interactions] High throughput no yes
SSRP1_HUMAN [view interactions] High throughput no yes
RMC1_HUMAN [view interactions] High throughput no no
H2AY_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
ENOA_HUMAN [view entry] [view interactions] Computational yes yes
G3P_HUMAN [view entry] [view interactions] Computational yes yes
PPID_HUMAN [view entry] [view interactions] Computational yes yes
RPGF3_HUMAN [view interactions] Computational no yes
CO7_HUMAN [view interactions] Computational no no
MFN2_HUMAN [view entry] [view interactions] Computational yes yes
MFF_HUMAN [view entry] [view interactions] Computational yes yes
CO5_HUMAN [view interactions] Computational no no
CO9_HUMAN [view interactions] Computational no no
CO8B_HUMAN [view interactions] Computational no no
HKDC1_HUMAN [view interactions] Computational no no
SDHA_HUMAN [view interactions] Computational no yes
MUL1_HUMAN [view interactions] Computational no no
MAT2B_HUMAN [view interactions] Computational no yes
MTX1_HUMAN [view entry] [view interactions] Computational yes yes
SODC_HUMAN [view interactions] Computational no yes
MFN1_HUMAN [view interactions] Computational no yes
ADT4_HUMAN [view entry] [view interactions] Computational yes no
MIRO1_HUMAN [view entry] [view interactions] Computational yes yes
TM40L_HUMAN [view entry] [view interactions] Computational yes yes
MDHM_HUMAN [view entry] [view interactions] Computational yes yes
IDE_HUMAN [view interactions] Computational no yes
UBB_HUMAN [view entry] [view interactions] Computational yes yes
RS27A_HUMAN [view entry] [view interactions] Computational yes yes
STAR_HUMAN [view interactions] Computational no no
NOS3_HUMAN [view interactions] Computational no no
HXK3_HUMAN [view interactions] Computational no no
CO8A_HUMAN [view interactions] Computational no no
FIS1_HUMAN [view entry] [view interactions] Computational yes yes
CO6_HUMAN [view interactions] Computational no yes
PTH2_HUMAN [view interactions] Computational no yes
ATG5_HUMAN [view interactions] Computational no no
BIP_HUMAN [view entry] [view interactions] Computational yes yes