Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ADT2_HUMAN

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell . Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane . In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity . Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis . Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) . Proton transporter activity requires free fatty acids as cofactor, but does not transport it . Probably mediates mitochondrial uncoupling in tissues that do not express UCP1 . Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death (PubMed). It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it . Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 . As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (PubMed). [View more on UniProt]

Interacting region for partners were not defined.

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No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ADT2_HUMAN
GO:0003723 RNA binding 38.4615 4 yes
GO:0043169 cation binding 25.0000 4 no
GO:0000166 nucleotide binding 24.3590 4 no
GO:0043168 anion binding 24.3590 4 no
GO:0046872 metal ion binding 23.0769 5 no
GO:0017076 purine nucleotide binding 22.4359 5 no
GO:0032555 purine ribonucleotide binding 21.1538 4 no
GO:0035639 purine ribonucleoside triphosphate binding 20.5128 4 no
GO:0044389 ubiquitin-like protein ligase binding 18.5897 4 yes
GO:0031625 ubiquitin protein ligase binding 17.9487 5 yes
GO:0008324 monoatomic cation transmembrane transporter activity 8.3333 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 8.3333 4 yes
GO:0015078 proton transmembrane transporter activity 4.4872 5 yes
GO:0015291 secondary active transmembrane transporter activity 2.5641 4 yes
GO:0015297 antiporter activity 2.5641 5 yes
GO:0000295 adenine nucleotide transmembrane transporter activity 1.9231 6 yes
GO:0005346 purine ribonucleotide transmembrane transporter activity 1.9231 4 yes
GO:0005347 ATP transmembrane transporter activity 1.9231 4 yes
GO:0005471 ATP:ADP antiporter activity 1.9231 5 yes
GO:0015215 nucleotide transmembrane transporter activity 1.9231 4 yes
GO:0015216 purine nucleotide transmembrane transporter activity 1.9231 5 yes
GO:0015217 ADP transmembrane transporter activity 1.9231 4 yes
GO:0005345 purine nucleobase transmembrane transporter activity 1.2821 4 yes
GO:0015207 adenine transmembrane transporter activity 1.2821 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ADT2_HUMAN
GO:0048522 positive regulation of cellular process 53.8462 4 yes
GO:0048523 negative regulation of cellular process 49.3590 4 yes
GO:0031323 regulation of cellular metabolic process 48.7179 4 yes
GO:0060255 regulation of macromolecule metabolic process 48.0769 4 no
GO:0080090 regulation of primary metabolic process 46.1538 4 no
GO:0009893 positive regulation of metabolic process 42.3077 4 yes
GO:0010646 regulation of cell communication 41.6667 4 yes
GO:0051128 regulation of cellular component organization 41.0256 4 yes
GO:0022607 cellular component assembly 39.1026 4 no
GO:0009966 regulation of signal transduction 38.4615 4 yes
GO:0009889 regulation of biosynthetic process 38.4615 4 no
GO:0010604 positive regulation of macromolecule metabolic process 37.8205 5 no
GO:0031326 regulation of cellular biosynthetic process 37.8205 5 no
GO:0010468 regulation of gene expression 36.5385 6 no
GO:0010556 regulation of macromolecule biosynthetic process 36.5385 5 no
GO:0051246 regulation of protein metabolic process 36.5385 5 no
GO:0006996 organelle organization 34.6154 4 yes
GO:0031325 positive regulation of cellular metabolic process 34.6154 5 yes
GO:0009892 negative regulation of metabolic process 32.0513 4 no
GO:0008104 protein localization 30.7692 4 no
GO:0042981 regulation of apoptotic process 30.1282 5 yes
GO:0043067 regulation of programmed cell death 30.1282 4 yes
GO:0048584 positive regulation of response to stimulus 29.4872 4 no
GO:1902531 regulation of intracellular signal transduction 28.8462 5 no
GO:0010605 negative regulation of macromolecule metabolic process 28.8462 5 no
GO:0051247 positive regulation of protein metabolic process 28.2051 6 no
GO:0043933 protein-containing complex organization 27.5641 4 no
GO:0031399 regulation of protein modification process 27.5641 6 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 26.9231 5 no
GO:0009059 macromolecule biosynthetic process 26.2821 4 no
GO:0009891 positive regulation of biosynthetic process 26.2821 5 no
GO:0031324 negative regulation of cellular metabolic process 26.2821 5 no
GO:0031328 positive regulation of cellular biosynthetic process 25.6410 6 no
GO:0009894 regulation of catabolic process 25.0000 4 yes
GO:0048585 negative regulation of response to stimulus 25.0000 4 yes
GO:0010557 positive regulation of macromolecule biosynthetic process 25.0000 6 no
GO:0010648 negative regulation of cell communication 24.3590 5 yes
GO:0023057 negative regulation of signaling 24.3590 4 yes
GO:0023056 positive regulation of signaling 24.3590 4 no
GO:0051049 regulation of transport 23.7179 4 yes
GO:0051130 positive regulation of cellular component organization 23.7179 5 yes
GO:0010647 positive regulation of cell communication 23.7179 5 no
GO:0009968 negative regulation of signal transduction 23.0769 5 yes
GO:0009967 positive regulation of signal transduction 22.4359 5 no
GO:0051252 regulation of RNA metabolic process 22.4359 5 no
GO:0071310 cellular response to organic substance 21.7949 4 yes
GO:1901566 organonitrogen compound biosynthetic process 21.7949 4 no
GO:0033043 regulation of organelle organization 21.1538 5 yes
GO:0071702 organic substance transport 21.1538 4 yes
GO:0071705 nitrogen compound transport 21.1538 4 yes
GO:0036211 protein modification process 21.1538 4 no
GO:0043412 macromolecule modification 21.1538 4 no
GO:0051240 positive regulation of multicellular organismal process 21.1538 4 no
GO:0006355 regulation of DNA-templated transcription 21.1538 7 no
GO:0044087 regulation of cellular component biogenesis 21.1538 4 no
GO:2001141 regulation of RNA biosynthetic process 21.1538 6 no
GO:0009890 negative regulation of biosynthetic process 21.1538 5 no
GO:0060341 regulation of cellular localization 21.1538 4 no
GO:0042127 regulation of cell population proliferation 20.5128 4 yes
GO:0043066 negative regulation of apoptotic process 20.5128 6 yes
GO:0043069 negative regulation of programmed cell death 20.5128 5 yes
GO:0065003 protein-containing complex assembly 20.5128 5 no
GO:0019220 regulation of phosphate metabolic process 20.5128 6 no
GO:0051174 regulation of phosphorus metabolic process 20.5128 5 no
GO:0008284 positive regulation of cell population proliferation 14.7436 5 yes
GO:0051129 negative regulation of cellular component organization 14.7436 5 yes
GO:0009896 positive regulation of catabolic process 14.1026 5 yes
GO:0010638 positive regulation of organelle organization 14.1026 6 yes
GO:0061024 membrane organization 12.8205 4 yes
GO:2001233 regulation of apoptotic signaling pathway 12.8205 5 yes
GO:0007005 mitochondrion organization 12.1795 5 yes
GO:0031329 regulation of cellular catabolic process 8.9744 5 yes
GO:2001234 negative regulation of apoptotic signaling pathway 8.9744 6 yes
GO:0010506 regulation of autophagy 8.3333 6 yes
GO:0010639 negative regulation of organelle organization 7.0513 6 yes
GO:0034097 response to cytokine 7.0513 4 yes
GO:0007006 mitochondrial membrane organization 6.4103 5 yes
GO:0006839 mitochondrial transport 5.7692 4 yes
GO:0010821 regulation of mitochondrion organization 5.7692 6 yes
GO:0031331 positive regulation of cellular catabolic process 5.7692 6 yes
GO:0071345 cellular response to cytokine stimulus 5.7692 5 yes
GO:0010508 positive regulation of autophagy 5.1282 7 yes
GO:0016241 regulation of macroautophagy 4.4872 7 yes
GO:0015931 nucleobase-containing compound transport 3.8462 5 yes
GO:0016239 positive regulation of macroautophagy 3.8462 8 yes
GO:0015711 organic anion transport 3.2051 5 yes
GO:0030099 myeloid cell differentiation 3.2051 4 yes
GO:0046902 regulation of mitochondrial membrane permeability 3.2051 4 yes
GO:1903146 regulation of autophagy of mitochondrion 3.2051 7 yes
GO:0002521 leukocyte differentiation 2.5641 4 yes
GO:0042113 B cell activation 2.5641 4 yes
GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.5641 5 yes
GO:1903131 mononuclear cell differentiation 2.5641 5 yes
GO:1903599 positive regulation of autophagy of mitochondrion 2.5641 7 yes
GO:0006862 nucleotide transport 1.9231 6 yes
GO:0015748 organophosphate ester transport 1.9231 5 yes
GO:0015865 purine nucleotide transport 1.9231 7 yes
GO:0015866 ADP transport 1.9231 6 yes
GO:0015867 ATP transport 1.9231 6 yes
GO:0015868 purine ribonucleotide transport 1.9231 6 yes
GO:0030098 lymphocyte differentiation 1.9231 4 yes
GO:0030218 erythrocyte differentiation 1.9231 5 yes
GO:0035795 negative regulation of mitochondrial membrane permeability 1.9231 5 yes
GO:0051503 adenine nucleotide transport 1.9231 8 yes
GO:0140021 mitochondrial ADP transmembrane transport 1.9231 4 yes
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1.9231 6 yes
GO:1901264 carbohydrate derivative transport 1.9231 5 yes
GO:1901524 regulation of mitophagy 1.9231 8 yes
GO:1901526 positive regulation of mitophagy 1.9231 8 yes
GO:1905709 negative regulation of membrane permeability 1.9231 4 yes
GO:1990544 mitochondrial ATP transmembrane transport 1.9231 4 yes
GO:0030183 B cell differentiation 1.2821 5 yes

Disease

No data found.

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
F16P1_HUMAN [view interactions] Low throughput no no
TIM44_HUMAN [view interactions] Low throughput no yes
RINI_HUMAN [view interactions] Low throughput no yes
SIR4_HUMAN [view interactions] Low throughput no yes
LRRK2_HUMAN [view interactions] Low throughput no yes
S35F6_HUMAN [view interactions] Low throughput no yes
RCC1L_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
ATPA_HUMAN [view interactions] High throughput no yes
CTCF_HUMAN [view interactions] High throughput no yes
OPA3_HUMAN [view interactions] High throughput no yes
TFE3_HUMAN [view interactions] High throughput no yes
SCOT1_HUMAN [view entry] [view interactions] High throughput yes yes
H4_HUMAN [view interactions] High throughput no yes
ADCK1_HUMAN [view interactions] High throughput no no
APEX1_HUMAN [view interactions] High throughput no yes
MIC27_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
COQ8B_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
FMC1_HUMAN [view interactions] High throughput no no
RBP56_HUMAN [view interactions] High throughput no yes
F136A_HUMAN [view interactions] High throughput no yes
ARAF_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
CLUA1_HUMAN [view interactions] High throughput no yes
SCOT2_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
PHIPL_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
MET14_HUMAN [view interactions] High throughput no yes
NFX1_HUMAN [view interactions] High throughput no yes
DICER_HUMAN [view entry] [view interactions] High throughput yes yes
BRD7_HUMAN [view interactions] High throughput no yes
NEK4_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
PRD16_HUMAN [view interactions] High throughput no no
TIF1B_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
SAP_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
CRY1_HUMAN [view interactions] High throughput no yes
TFCP2_HUMAN [view interactions] High throughput no no
VAV_HUMAN [view interactions] High throughput no no
TRIM6_HUMAN [view interactions] High throughput no no
RASA1_HUMAN [view interactions] High throughput no yes
ZCH18_HUMAN [view interactions] High throughput no yes
MK07_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
RALB_HUMAN [view interactions] High throughput no no
SNIP1_HUMAN [view interactions] High throughput no no
PAXI_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
LRC31_HUMAN [view interactions] High throughput no no
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
NMRL1_HUMAN [view interactions] High throughput no yes
MTA2_HUMAN [view interactions] High throughput no yes
ODFP2_HUMAN [view interactions] High throughput no no
M3K14_HUMAN [view interactions] High throughput no yes
BRD4_HUMAN [view interactions] High throughput no yes
KPCE_HUMAN [view entry] [view interactions] High throughput yes yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
ELK1_HUMAN [view interactions] High throughput no yes
CIC_HUMAN [view interactions] High throughput no yes
PAK1_HUMAN [view entry] [view interactions] High throughput yes yes
UBR5_HUMAN [view interactions] High throughput no no
KPCG_HUMAN [view entry] [view interactions] High throughput yes yes
CFAD_HUMAN [view interactions] High throughput no no
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
FNDC5_HUMAN [view interactions] High throughput no no
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
RBM39_HUMAN [view interactions] High throughput no yes
HDAC1_HUMAN [view interactions] High throughput no no
CBX1_HUMAN [view interactions] High throughput no yes
CSK_HUMAN [view interactions] High throughput no yes
MT21E_HUMAN [view interactions] High throughput no no
ACK1_HUMAN [view entry] [view interactions] High throughput yes yes
IF16_HUMAN [view interactions] High throughput no no
MYLK2_HUMAN [view interactions] High throughput no no
WDR76_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
KDF1_HUMAN [view interactions] High throughput no yes
MSPD2_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
NCBP3_HUMAN [view interactions] High throughput no yes
SPOP_HUMAN [view interactions] High throughput no no
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
ANDR_HUMAN [view interactions] High throughput no no
MOT11_HUMAN [view interactions] High throughput no no
UFL1_HUMAN [view interactions] High throughput no yes
PPM1E_HUMAN [view entry] [view interactions] High throughput yes yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
PPM1A_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
RBM45_HUMAN [view interactions] High throughput no yes
WDR5_HUMAN [view interactions] High throughput no no
SIM26_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
GRID2_HUMAN [view entry] [view interactions] High throughput yes no
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
CD80_HUMAN [view interactions] High throughput no no
VCAM1_HUMAN [view interactions] High throughput no no
LCFC1_HUMAN [view interactions] High throughput no no
CDK1_HUMAN [view interactions] High throughput no no
LRP1_HUMAN [view entry] [view interactions] High throughput yes yes
COX15_HUMAN [view interactions] High throughput no yes
I13R2_HUMAN [view interactions] High throughput no no
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
OSTM1_HUMAN [view interactions] High throughput no yes
SDHA_HUMAN [view interactions] High throughput no yes
ISLR_HUMAN [view interactions] High throughput no no
SOAT1_HUMAN [view interactions] High throughput no no
GLMP_HUMAN [view interactions] High throughput no no
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
TBC17_HUMAN [view entry] [view interactions] High throughput yes yes
RHG28_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
BDP1_HUMAN [view interactions] High throughput no no
SPRTN_HUMAN [view interactions] High throughput no yes
PMFBP_HUMAN [view interactions] High throughput no yes
BTF3_HUMAN [view interactions] High throughput no yes
BACE1_HUMAN [view interactions] High throughput no yes
THB_HUMAN [view interactions] High throughput no no
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
FBXW7_HUMAN [view interactions] High throughput no yes
RD23B_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
E2F3_HUMAN [view interactions] High throughput no no
TM11B_HUMAN [view interactions] High throughput no no
MEX3C_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
NCK2_HUMAN [view entry] [view interactions] High throughput yes yes
CD3Z_HUMAN [view interactions] High throughput no no
CCNF_HUMAN [view interactions] High throughput no no
DUX4_HUMAN [view interactions] High throughput no no
ZN363_HUMAN [view interactions] High throughput no yes
PSN1_HUMAN [view entry] [view interactions] High throughput yes yes
HECD1_HUMAN [view interactions] High throughput no yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
OXLA_HUMAN [view interactions] High throughput no no
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
ZEB1_HUMAN [view interactions] High throughput no yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
CFTR_HUMAN [view interactions] High throughput no no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
PSB10_HUMAN [view interactions] High throughput no no
PHAG1_HUMAN [view interactions] High throughput no yes
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
CBL_HUMAN [view interactions] High throughput no yes
TRI31_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
ANM1_HUMAN [view interactions] High throughput no yes
NTRK1_HUMAN [view interactions] High throughput no yes
SHCAF_HUMAN [view interactions] High throughput no yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
FOLR1_HUMAN [view interactions] High throughput no no
TYRO3_HUMAN [view interactions] High throughput no yes
MYCN_HUMAN [view interactions] High throughput no no
EGFR_HUMAN [view interactions] High throughput no no
SIR2_HUMAN [view entry] [view interactions] High throughput yes yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
IF2B3_HUMAN [view interactions] High throughput no no
TERA_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
IKZF1_HUMAN [view interactions] High throughput no no
C560_HUMAN [view interactions] High throughput no no
IKZF3_HUMAN [view interactions] High throughput no no
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
HDAC6_HUMAN [view interactions] High throughput no yes
DHSD_HUMAN [view interactions] High throughput no yes
AT1A1_HUMAN [view entry] [view interactions] High throughput yes no
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
ARMC5_HUMAN [view interactions] High throughput no yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
MAP1B_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
ZRAN1_HUMAN [view interactions] High throughput no yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
DOT1L_HUMAN [view interactions] High throughput no yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
PKHA5_HUMAN [view entry] [view interactions] High throughput yes yes
SDHB_HUMAN [view interactions] High throughput no yes
TIF1A_HUMAN [view interactions] High throughput no yes
JUN_HUMAN [view interactions] High throughput no yes
AATF_HUMAN [view interactions] High throughput no yes
HSPB2_HUMAN [view interactions] High throughput no yes
LOXL2_HUMAN [view interactions] High throughput no yes
RD3_HUMAN [view interactions] High throughput no no
R113A_HUMAN [view interactions] High throughput no yes
LITD1_HUMAN [view interactions] High throughput no no
TBX5_HUMAN [view interactions] High throughput no no
TCTP_HUMAN [view entry] [view interactions] High throughput yes yes
GATA4_HUMAN [view interactions] High throughput no no
CD177_HUMAN [view interactions] High throughput no no
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
CHIC2_HUMAN [view interactions] High throughput no no
EGLN_HUMAN [view interactions] High throughput no no
CDK7_HUMAN [view interactions] High throughput no yes
ITM2B_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
BMI1_HUMAN [view interactions] High throughput no yes
GBRA1_HUMAN [view entry] [view interactions] High throughput yes yes
CNDD3_HUMAN [view interactions] High throughput no no
RAF1_HUMAN [view entry] [view interactions] High throughput yes no
CAC1C_HUMAN [view entry] [view interactions] High throughput yes no
MILK2_HUMAN [view interactions] High throughput no no
HCN1_HUMAN [view entry] [view interactions] High throughput yes yes
RUFY1_HUMAN [view interactions] High throughput no yes
DYR1A_HUMAN [view interactions] High throughput no yes
TRI67_HUMAN [view interactions] High throughput no no
IKBA_HUMAN [view interactions] High throughput no yes
CBX3_HUMAN [view interactions] High throughput no yes
NEMO_HUMAN [view interactions] High throughput no yes
CBX5_HUMAN [view interactions] High throughput no yes
M3K1_HUMAN [view interactions] High throughput no yes
STIP1_HUMAN [view entry] [view interactions] High throughput yes yes
M3K3_HUMAN [view interactions] High throughput no no
FBW1A_HUMAN [view interactions] High throughput no yes
RIPK1_HUMAN [view interactions] High throughput no yes
MBD5_HUMAN [view interactions] High throughput no no
RIPK3_HUMAN [view interactions] High throughput no no
MBD6_HUMAN [view interactions] High throughput no yes
TNR1A_HUMAN [view interactions] High throughput no yes
ASXL1_HUMAN [view interactions] High throughput no no
TNR1B_HUMAN [view interactions] High throughput no no
ASXL2_HUMAN [view interactions] High throughput no no
TRADD_HUMAN [view interactions] High throughput no yes
ASXL3_HUMAN [view interactions] High throughput no no
TRAF1_HUMAN [view interactions] High throughput no no
UBP48_HUMAN [view interactions] High throughput no yes
TRAF2_HUMAN [view interactions] High throughput no yes
DDR1_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
DDR2_HUMAN [view interactions] High throughput no no
TONSL_HUMAN [view interactions] High throughput no no
PIAS1_HUMAN [view entry] [view interactions] High throughput yes yes
HDGF_HUMAN [view interactions] High throughput no yes
FND3A_HUMAN [view interactions] High throughput no yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
DDX24_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
HSF1_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
ARC1B_HUMAN [view interactions] High throughput no no
DCNL1_HUMAN [view interactions] High throughput no yes
EZH2_HUMAN [view interactions] High throughput no no
CSN5_HUMAN [view interactions] High throughput no yes
MIDN_HUMAN [view interactions] High throughput no no
CUL2_HUMAN [view interactions] High throughput no yes
RN207_HUMAN [view interactions] High throughput no no
CUL4B_HUMAN [view interactions] High throughput no yes
RICTR_HUMAN [view interactions] High throughput no yes
CSN6_HUMAN [view interactions] High throughput no yes
SMC5_HUMAN [view interactions] High throughput no yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ANLN_HUMAN [view interactions] High throughput no yes
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
PML_HUMAN [view interactions] High throughput no yes
5HT7R_HUMAN [view entry] [view interactions] High throughput yes yes
B3GN2_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
UBE2H_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
UBP25_HUMAN [view interactions] High throughput no yes
FAKD3_HUMAN [view interactions] High throughput no yes
TNIP1_HUMAN [view interactions] High throughput no yes
B9D1_HUMAN [view interactions] High throughput no yes
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
ECSIT_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
ATD3A_HUMAN [view entry] [view interactions] High throughput yes yes
ITA2B_HUMAN [view interactions] High throughput no no
TIFAB_HUMAN [view interactions] High throughput no no
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
A2MG_HUMAN [view interactions] High throughput no yes
RL37A_HUMAN [view entry] [view interactions] High throughput yes yes
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
COX14_HUMAN [view interactions] High throughput no yes
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
COX1_HUMAN [view interactions] High throughput no yes
RL14_HUMAN [view entry] [view interactions] High throughput yes yes
COXM1_HUMAN [view entry] [view interactions] High throughput yes yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
RDH13_HUMAN [view interactions] High throughput no no
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
RM40_HUMAN [view interactions] High throughput no yes
RS15A_HUMAN [view entry] [view interactions] High throughput yes yes
RM46_HUMAN [view interactions] High throughput no yes
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
RM48_HUMAN [view interactions] High throughput no yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
SIM20_HUMAN [view interactions] High throughput no yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
SURF1_HUMAN [view interactions] High throughput no yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
TIM21_HUMAN [view interactions] High throughput no yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
TM223_HUMAN [view interactions] High throughput no yes
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
NECD_HUMAN [view interactions] High throughput no no
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
RL21_HUMAN [view entry] [view interactions] High throughput yes yes
NOP56_HUMAN [view interactions] High throughput no yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
SHIP2_HUMAN [view interactions] High throughput no yes
RL23A_HUMAN [view entry] [view interactions] High throughput yes yes
FBX6_HUMAN [view interactions] High throughput no yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
LIPC_HUMAN [view interactions] High throughput no no
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
FINC_HUMAN [view interactions] High throughput no yes
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
NOS2_HUMAN [view interactions] High throughput no yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
RL9_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
RS8_HUMAN [view entry] [view interactions] High throughput yes no
CLN3_HUMAN [view interactions] High throughput no no
RS21_HUMAN [view entry] [view interactions] High throughput yes yes
CLN5_HUMAN [view interactions] High throughput no yes
RSSA_HUMAN [view entry] [view interactions] High throughput yes yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
RS28_HUMAN [view entry] [view interactions] High throughput yes yes
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
RT16_HUMAN [view interactions] High throughput no yes
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
TADBP_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
LEG3_HUMAN [view interactions] High throughput no yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
ASB3_HUMAN [view interactions] High throughput no yes
GRHPR_HUMAN [view entry] [view interactions] High throughput yes no
ASB6_HUMAN [view interactions] High throughput no yes
K2C1_HUMAN [view interactions] High throughput no no
ASB10_HUMAN [view interactions] High throughput no no
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
ASB14_HUMAN [view interactions] High throughput no no
RT34_HUMAN [view interactions] High throughput no yes
ASB18_HUMAN [view interactions] High throughput no no
NPTN_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF2_HUMAN [view interactions] High throughput no yes
ANX11_HUMAN [view entry] [view interactions] High throughput yes yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB3_HUMAN [view interactions] High throughput no yes
HNRPU_HUMAN [view interactions] High throughput no yes
ERR2_HUMAN [view interactions] High throughput no no
NDUS4_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
PMM2_HUMAN [view interactions] High throughput no no
LGR4_HUMAN [view interactions] High throughput no yes
MCAT_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
SCMC1_HUMAN [view interactions] High throughput no no
P53_HUMAN [view interactions] High throughput no no
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
HUWE1_HUMAN [view interactions] High throughput no yes
TOM20_HUMAN [view entry] [view interactions] High throughput yes yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
ATPMK_HUMAN [view interactions] High throughput no no
OBSL1_HUMAN [view interactions] High throughput no yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
EED_HUMAN [view interactions] High throughput no yes
SC61B_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
ATPO_HUMAN [view interactions] High throughput no yes
GAN_HUMAN [view interactions] High throughput no yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
SKI_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
PODO_HUMAN [view interactions] High throughput no no
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
MCM2_HUMAN [view interactions] High throughput no no
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
MCM5_HUMAN [view interactions] High throughput no no
PSA3_HUMAN [view interactions] High throughput no no
MERL_HUMAN [view interactions] High throughput no yes
ATPG_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
RN126_HUMAN [view interactions] High throughput no yes
ATP5L_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
RC3H1_HUMAN [view interactions] High throughput no yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
ATX1_HUMAN [view interactions] High throughput no yes
WWP2_HUMAN [view interactions] High throughput no no
RBM47_HUMAN [view interactions] High throughput no yes
ZN746_HUMAN [view interactions] High throughput no no
TMM70_HUMAN [view interactions] High throughput no yes
FACD2_HUMAN [view interactions] High throughput no no
LEG9_HUMAN [view interactions] High throughput no yes
GLUT4_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
COIL_HUMAN [view interactions] High throughput no yes
AGO1_HUMAN [view interactions] High throughput no no
TRI25_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
AGO2_HUMAN [view entry] [view interactions] High throughput yes yes
YAP1_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
AGO4_HUMAN [view interactions] High throughput no no
ATX3_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
ZN598_HUMAN [view interactions] High throughput no no
STING_HUMAN [view interactions] High throughput no yes
FBX7_HUMAN [view interactions] High throughput no yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
DX39B_HUMAN [view interactions] High throughput no no
PCDH7_HUMAN [view entry] [view interactions] High throughput yes no
MLP3B_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3B_HUMAN [view entry] [view interactions] High throughput yes yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
GSK3A_HUMAN [view interactions] High throughput no yes
GBRL1_HUMAN [view interactions] High throughput no yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
FOXO1_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view entry] [view interactions] High throughput yes no
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
RFA1_HUMAN [view interactions] High throughput no yes
ICT1_HUMAN [view interactions] High throughput no yes
TGFB1_HUMAN [view interactions] High throughput no no
RFA2_HUMAN [view interactions] High throughput no yes
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
HIF1N_HUMAN [view interactions] High throughput no yes
RFA3_HUMAN [view interactions] High throughput no yes
EGLN3_HUMAN [view interactions] High throughput no no
RFA4_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
MGN_HUMAN [view interactions] High throughput no yes
U5S1_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
AAR2_HUMAN [view interactions] High throughput no no
MK06_HUMAN [view interactions] High throughput no yes
PIHD1_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
OTUB1_HUMAN [view interactions] High throughput no yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
HEM6_HUMAN [view interactions] High throughput no no
TNIP2_HUMAN [view interactions] High throughput no yes
HEMH_HUMAN [view interactions] High throughput no yes
RNF4_HUMAN [view interactions] High throughput no yes
PPOX_HUMAN [view interactions] High throughput no no
CHD3_HUMAN [view interactions] High throughput no yes
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
CHD4_HUMAN [view interactions] High throughput no yes
ITB1_HUMAN [view entry] [view interactions] High throughput yes no
RNF31_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
TNFA_HUMAN [view interactions] High throughput no no
NICA_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
CCND1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
TBA1C_HUMAN [view interactions] High throughput no yes
LARP7_HUMAN [view interactions] High throughput no yes
IFT88_HUMAN [view interactions] High throughput no no
RN123_HUMAN [view interactions] High throughput no yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
PPT1_HUMAN [view interactions] High throughput no yes
PGRC2_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
CCNJL_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
DKK3_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
DCPS_HUMAN [view interactions] High throughput no yes
RRP1B_HUMAN [view interactions] High throughput no yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
ADCK2_HUMAN [view interactions] High throughput no yes
REST_HUMAN [view interactions] High throughput no yes
NMES1_HUMAN [view interactions] High throughput no no
SOCS1_HUMAN [view interactions] High throughput no yes
NDUF8_HUMAN [view interactions] High throughput no no
MYC_HUMAN [view interactions] High throughput no yes
MAIP1_HUMAN [view interactions] High throughput no yes
CDK9_HUMAN [view interactions] High throughput no yes
HDHD5_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
CHC10_HUMAN [view interactions] High throughput no yes
K1C17_HUMAN [view interactions] High throughput no no
CHCH2_HUMAN [view interactions] High throughput no yes
VIR_HUMAN [view interactions] High throughput no yes
CISD3_HUMAN [view interactions] High throughput no yes
PKHA2_HUMAN [view interactions] High throughput no no
COQ2_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
COQ6_HUMAN [view interactions] High throughput no yes
FAF1_HUMAN [view interactions] High throughput no yes
COQ9_HUMAN [view interactions] High throughput no yes
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
TM41B_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
TGM2_HUMAN [view interactions] High throughput no no
OCAD1_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
PTPM1_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes