Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

ADT2_HUMAN

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell . Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane . In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity . Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis . Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity) . Proton transporter activity requires free fatty acids as cofactor, but does not transport it . Probably mediates mitochondrial uncoupling in tissues that do not express UCP1 . Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death (PubMed). It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it . Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 . As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (PubMed). [View more on UniProt]

Interacting region for partners were not defined.

Download full PS network for entry.

No data found.

No data found.

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Molecular function

Term Name % Distance from the top of the tree Annotated in ADT2_HUMAN
GO:0003723 RNA binding 41.0072 4 yes
GO:0044389 ubiquitin-like protein ligase binding 15.1079 4 yes
GO:0031625 ubiquitin protein ligase binding 14.3885 5 yes
GO:0008509 anion transmembrane transporter activity 6.4748 4 yes
GO:0008324 cation transmembrane transporter activity 5.7554 4 yes
GO:0022853 active ion transmembrane transporter activity 5.7554 4 yes
GO:0022890 inorganic cation transmembrane transporter activity 5.7554 4 yes
GO:0008514 organic anion transmembrane transporter activity 3.5971 5 yes
GO:0015078 proton transmembrane transporter activity 3.5971 5 yes
GO:0015291 secondary active transmembrane transporter activity 3.5971 4 yes
GO:0000295 adenine nucleotide transmembrane transporter activity 2.8777 6 yes
GO:0005346 purine ribonucleotide transmembrane transporter activity 2.8777 4 yes
GO:0005347 ATP transmembrane transporter activity 2.8777 5 yes
GO:0005471 ATP:ADP antiporter activity 2.8777 5 yes
GO:0015215 nucleotide transmembrane transporter activity 2.8777 4 yes
GO:0015216 purine nucleotide transmembrane transporter activity 2.8777 5 yes
GO:0015217 ADP transmembrane transporter activity 2.8777 5 yes
GO:0015297 antiporter activity 2.8777 5 yes
GO:0140323 solute:anion antiporter activity 2.8777 6 yes
GO:0005345 purine nucleobase transmembrane transporter activity 1.4388 4 yes
GO:0015207 adenine transmembrane transporter activity 1.4388 5 yes

Biological process

Term Name % Distance from top the of the tree Annotated in ADT2_HUMAN
GO:0048522 positive regulation of cellular process 53.2374 4 yes
GO:0060255 regulation of macromolecule metabolic process 46.7626 4 no
GO:0048523 negative regulation of cellular process 46.7626 4 yes
GO:0031323 regulation of cellular metabolic process 46.0432 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 44.6043 4 no
GO:0080090 regulation of primary metabolic process 44.6043 4 no
GO:0009893 positive regulation of metabolic process 40.2878 4 yes
GO:0010646 regulation of cell communication 38.8489 4 yes
GO:0051128 regulation of cellular component organization 38.1295 4 yes
GO:0010468 regulation of gene expression 37.4101 5 no
GO:0022607 cellular component assembly 35.9712 4 no
GO:0010604 positive regulation of macromolecule metabolic process 35.2518 5 no
GO:0009966 regulation of signal transduction 35.2518 4 yes
GO:0051246 regulation of protein metabolic process 34.5324 5 no
GO:0006996 organelle organization 33.8129 4 yes
GO:0009892 negative regulation of metabolic process 30.9353 4 no
GO:0051173 positive regulation of nitrogen compound metabolic process 30.2158 5 no
GO:0010941 regulation of cell death 30.2158 4 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 29.4964 5 no
GO:0031326 regulation of cellular biosynthetic process 29.4964 5 no
GO:0031325 positive regulation of cellular metabolic process 29.4964 5 yes
GO:0009889 regulation of biosynthetic process 29.4964 4 no
GO:0010605 negative regulation of macromolecule metabolic process 28.7770 5 no
GO:1902531 regulation of intracellular signal transduction 28.7770 5 no
GO:0010556 regulation of macromolecule biosynthetic process 28.7770 5 no
GO:0043067 regulation of programmed cell death 28.0576 5 yes
GO:0042981 regulation of apoptotic process 27.3381 6 yes
GO:0008104 protein localization 27.3381 4 no
GO:0051172 negative regulation of nitrogen compound metabolic process 26.6187 5 no
GO:0031399 regulation of protein modification process 25.8993 6 no
GO:0051247 positive regulation of protein metabolic process 25.8993 6 no
GO:0031324 negative regulation of cellular metabolic process 25.1799 5 no
GO:0048584 positive regulation of response to stimulus 25.1799 4 no
GO:0051252 regulation of RNA metabolic process 25.1799 5 no
GO:0071702 organic substance transport 25.1799 4 yes
GO:0044271 cellular nitrogen compound biosynthetic process 25.1799 4 no
GO:0071705 nitrogen compound transport 24.4604 4 yes
GO:0009059 macromolecule biosynthetic process 24.4604 4 no
GO:0010647 positive regulation of cell communication 23.7410 5 no
GO:0023056 positive regulation of signaling 23.7410 4 no
GO:1903506 regulation of nucleic acid-templated transcription 23.7410 7 no
GO:2001141 regulation of RNA biosynthetic process 23.7410 6 no
GO:0043603 cellular amide metabolic process 23.7410 4 no
GO:0006355 regulation of DNA-templated transcription 23.7410 6 no
GO:0010628 positive regulation of gene expression 23.0216 6 no
GO:0051130 positive regulation of cellular component organization 23.0216 5 yes
GO:0071310 cellular response to organic substance 23.0216 4 yes
GO:1901566 organonitrogen compound biosynthetic process 23.0216 4 no
GO:0036211 protein modification process 22.3022 4 no
GO:0043412 macromolecule modification 22.3022 4 no
GO:0009894 regulation of catabolic process 22.3022 4 yes
GO:0051049 regulation of transport 22.3022 4 yes
GO:0006518 peptide metabolic process 22.3022 4 no
GO:0034645 cellular macromolecule biosynthetic process 22.3022 4 no
GO:0043604 amide biosynthetic process 22.3022 5 no
GO:0048585 negative regulation of response to stimulus 21.5827 4 yes
GO:0043933 protein-containing complex organization 21.5827 4 no
GO:0002181 cytoplasmic translation 21.5827 5 no
GO:0006412 translation 21.5827 4 no
GO:0043043 peptide biosynthetic process 21.5827 5 no
GO:0009967 positive regulation of signal transduction 21.5827 5 no
GO:0019220 regulation of phosphate metabolic process 20.8633 6 no
GO:0051174 regulation of phosphorus metabolic process 20.8633 5 no
GO:0033043 regulation of organelle organization 20.8633 5 yes
GO:0042127 regulation of cell population proliferation 20.8633 4 yes
GO:0060548 negative regulation of cell death 20.8633 5 yes
GO:0060341 regulation of cellular localization 20.1439 4 no
GO:0010648 negative regulation of cell communication 20.1439 5 yes
GO:0023057 negative regulation of signaling 20.1439 4 yes
GO:0043069 negative regulation of programmed cell death 20.1439 6 yes
GO:0043066 negative regulation of apoptotic process 19.4245 7 yes
GO:0009968 negative regulation of signal transduction 18.7050 5 yes
GO:0008284 positive regulation of cell population proliferation 16.5468 5 yes
GO:0031329 regulation of cellular catabolic process 16.5468 5 yes
GO:0010638 positive regulation of organelle organization 14.3885 6 yes
GO:0061024 membrane organization 12.9496 4 yes
GO:0007005 mitochondrion organization 11.5108 5 yes
GO:0051129 negative regulation of cellular component organization 11.5108 5 yes
GO:0009896 positive regulation of catabolic process 10.7914 5 yes
GO:2001233 regulation of apoptotic signaling pathway 10.7914 5 yes
GO:0006811 ion transport 9.3525 4 yes
GO:0010506 regulation of autophagy 7.9137 6 yes
GO:0031331 positive regulation of cellular catabolic process 7.9137 6 yes
GO:2001234 negative regulation of apoptotic signaling pathway 7.1942 6 yes
GO:0006820 anion transport 5.7554 5 yes
GO:0007006 mitochondrial membrane organization 5.7554 5 yes
GO:0015931 nucleobase-containing compound transport 5.7554 5 yes
GO:0010508 positive regulation of autophagy 5.0360 7 yes
GO:0010639 negative regulation of organelle organization 5.0360 6 yes
GO:0010821 regulation of mitochondrion organization 5.0360 6 yes
GO:0016241 regulation of macroautophagy 5.0360 7 yes
GO:0015711 organic anion transport 4.3165 5 yes
GO:0016239 positive regulation of macroautophagy 4.3165 8 yes
GO:0034097 response to cytokine 4.3165 4 yes
GO:0002521 leukocyte differentiation 3.5971 4 yes
GO:0010822 positive regulation of mitochondrion organization 3.5971 7 yes
GO:0030099 myeloid cell differentiation 3.5971 4 yes
GO:0071345 cellular response to cytokine stimulus 3.5971 5 yes
GO:0098656 anion transmembrane transport 3.5971 4 yes
GO:1903131 mononuclear cell differentiation 3.5971 5 yes
GO:1903146 regulation of autophagy of mitochondrion 3.5971 7 yes
GO:0006862 nucleotide transport 2.8777 6 yes
GO:0010823 negative regulation of mitochondrion organization 2.8777 7 yes
GO:0015748 organophosphate ester transport 2.8777 5 yes
GO:0015865 purine nucleotide transport 2.8777 7 yes
GO:0015866 ADP transport 2.8777 6 yes
GO:0015867 ATP transport 2.8777 6 yes
GO:0015868 purine ribonucleotide transport 2.8777 6 yes
GO:0030098 lymphocyte differentiation 2.8777 4 yes
GO:0042113 B cell activation 2.8777 4 yes
GO:0046902 regulation of mitochondrial membrane permeability 2.8777 4 yes
GO:0051503 adenine nucleotide transport 2.8777 8 yes
GO:0140021 mitochondrial ADP transmembrane transport 2.8777 4 yes
GO:1901264 carbohydrate derivative transport 2.8777 5 yes
GO:1903599 positive regulation of autophagy of mitochondrion 2.8777 8 yes
GO:1990544 mitochondrial ATP transmembrane transport 2.8777 4 yes
GO:0030218 erythrocyte differentiation 2.1583 5 yes
GO:1901524 regulation of mitophagy 2.1583 8 yes
GO:1901526 positive regulation of mitophagy 2.1583 9 yes
GO:0030183 B cell differentiation 1.4388 5 yes

Disease

Term Name % Distance from top the of the tree Annotated in ADT2_HUMAN
DOID:1289 neurodegenerative disease 2.8777 4 no
DOID:331 central nervous system disease 2.8777 3 no
DOID:574 peripheral nervous system disease 2.8777 3 no
DOID:870 neuropathy 2.8777 4 no
DOID:10595 Charcot-Marie-Tooth disease 2.1583 6 no
DOID:440 neuromuscular disease 2.1583 5 no
DOID:0050539 Charcot-Marie-Tooth disease type 2 1.4388 7 no
DOID:231 motor neuron disease 1.4388 5 no
DOID:37 skin disease 1.4388 3 no
DOID:0050686 organ system cancer 1.4388 3 no
DOID:120 female reproductive organ cancer 1.4388 5 no
DOID:193 reproductive organ cancer 1.4388 4 no
DOID:0050700 cardiomyopathy 1.4388 4 no
DOID:0060036 intrinsic cardiomyopathy 1.4388 5 no
DOID:0080000 muscular disease 1.4388 3 no
DOID:114 heart disease 1.4388 3 no
DOID:12930 dilated cardiomyopathy 1.4388 6 no
DOID:423 myopathy 1.4388 5 no
DOID:66 muscle tissue disease 1.4388 4 no
Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
LRRK2_HUMAN [view interactions] Low throughput no yes
S35F6_HUMAN [view interactions] Low throughput no yes
F16P1_HUMAN [view interactions] Low throughput no no
TIM44_HUMAN [view interactions] Low throughput no yes
RINI_HUMAN [view interactions] Low throughput no yes
SIR4_HUMAN [view interactions] Low throughput no yes
GBRL2_HUMAN [view entry] [view interactions] High throughput yes yes
EGLN3_HUMAN [view interactions] High throughput no no
GBRL1_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
GBRAP_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
ICT1_HUMAN [view interactions] High throughput no yes
AAR2_HUMAN [view interactions] High throughput no no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
PIHD1_HUMAN [view interactions] High throughput no yes
UBC12_HUMAN [view entry] [view interactions] High throughput yes yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
MGN_HUMAN [view interactions] High throughput no yes
TNIP2_HUMAN [view interactions] High throughput no yes
ILK_HUMAN [view interactions] High throughput no no
RNF4_HUMAN [view interactions] High throughput no yes
MK06_HUMAN [view interactions] High throughput no yes
CHD3_HUMAN [view interactions] High throughput no yes
RIPK4_HUMAN [view interactions] High throughput no no
CHD4_HUMAN [view interactions] High throughput no yes
OTUB1_HUMAN [view interactions] High throughput no yes
RNF31_HUMAN [view interactions] High throughput no yes
HEM6_HUMAN [view interactions] High throughput no no
TNFA_HUMAN [view interactions] High throughput no no
HEMH_HUMAN [view interactions] High throughput no yes
HEXI1_HUMAN [view interactions] High throughput no yes
PPOX_HUMAN [view interactions] High throughput no no
MEPCE_HUMAN [view interactions] High throughput no yes
TBG1_HUMAN [view entry] [view interactions] High throughput yes yes
LARP7_HUMAN [view interactions] High throughput no yes
ITB1_HUMAN [view entry] [view interactions] High throughput yes no
RN123_HUMAN [view interactions] High throughput no yes
RB11A_HUMAN [view entry] [view interactions] High throughput yes yes
PPT1_HUMAN [view interactions] High throughput no yes
NICA_HUMAN [view interactions] High throughput no yes
SNAI1_HUMAN [view interactions] High throughput no yes
CCND1_HUMAN [view interactions] High throughput no yes
AGR2_HUMAN [view interactions] High throughput no no
TBA1C_HUMAN [view interactions] High throughput no yes
RECQ4_HUMAN [view interactions] High throughput no yes
IFT88_HUMAN [view interactions] High throughput no no
DCPS_HUMAN [view interactions] High throughput no yes
PGRC1_HUMAN [view entry] [view interactions] High throughput yes yes
NEB2_HUMAN [view entry] [view interactions] High throughput yes yes
PGRC2_HUMAN [view interactions] High throughput no yes
REST_HUMAN [view interactions] High throughput no yes
CCNJL_HUMAN [view interactions] High throughput no yes
SOCS1_HUMAN [view interactions] High throughput no yes
DKK3_HUMAN [view interactions] High throughput no yes
MYC_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
CDK9_HUMAN [view interactions] High throughput no yes
RRP1B_HUMAN [view interactions] High throughput no yes
AAKB1_HUMAN [view interactions] High throughput no yes
ADCK2_HUMAN [view interactions] High throughput no yes
K1C17_HUMAN [view interactions] High throughput no no
NMES1_HUMAN [view interactions] High throughput no no
VIR_HUMAN [view interactions] High throughput no yes
NDUF8_HUMAN [view interactions] High throughput no no
PKHA2_HUMAN [view interactions] High throughput no no
MAIP1_HUMAN [view interactions] High throughput no yes
RC3H2_HUMAN [view interactions] High throughput no yes
HDHD5_HUMAN [view interactions] High throughput no yes
FAF1_HUMAN [view interactions] High throughput no yes
CHC10_HUMAN [view interactions] High throughput no yes
RBX1_HUMAN [view entry] [view interactions] High throughput yes no
CHCH2_HUMAN [view interactions] High throughput no yes
TM41B_HUMAN [view interactions] High throughput no yes
CISD3_HUMAN [view interactions] High throughput no yes
TGM2_HUMAN [view interactions] High throughput no no
COQ6_HUMAN [view interactions] High throughput no yes
NR2C2_HUMAN [view interactions] High throughput no yes
COQ2_HUMAN [view interactions] High throughput no yes
UBQL2_HUMAN [view interactions] High throughput no yes
COQ9_HUMAN [view interactions] High throughput no yes
GLUC_HUMAN [view interactions] High throughput no no
NDUA4_HUMAN [view entry] [view interactions] High throughput yes yes
CTCF_HUMAN [view interactions] High throughput no yes
NDUS3_HUMAN [view entry] [view interactions] High throughput yes yes
TFE3_HUMAN [view interactions] High throughput no yes
OCAD1_HUMAN [view interactions] High throughput no yes
H4_HUMAN [view interactions] High throughput no yes
PTPM1_HUMAN [view interactions] High throughput no yes
APEX1_HUMAN [view interactions] High throughput no yes
RCC1L_HUMAN [view interactions] High throughput no yes
HSPB1_HUMAN [view entry] [view interactions] High throughput yes no
ATPA_HUMAN [view interactions] High throughput no yes
TIP_HUMAN [view entry] [view interactions] High throughput yes yes
OPA3_HUMAN [view interactions] High throughput no yes
RBP56_HUMAN [view interactions] High throughput no yes
SCOT1_HUMAN [view entry] [view interactions] High throughput yes yes
ARAF_HUMAN [view interactions] High throughput no yes
MIC27_HUMAN [view entry] [view interactions] High throughput yes yes
CLUA1_HUMAN [view interactions] High throughput no yes
ADCK1_HUMAN [view interactions] High throughput no no
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
COQ8B_HUMAN [view interactions] High throughput no yes
BIRC3_HUMAN [view interactions] High throughput no no
FMC1_HUMAN [view interactions] High throughput no no
NFX1_HUMAN [view interactions] High throughput no yes
F136A_HUMAN [view interactions] High throughput no yes
BRD7_HUMAN [view interactions] High throughput no yes
SPT20_HUMAN [view interactions] High throughput no yes
SOX2_HUMAN [view interactions] High throughput no yes
PHIPL_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
SCOT2_HUMAN [view interactions] High throughput no no
PKHA4_HUMAN [view interactions] High throughput no yes
MET14_HUMAN [view interactions] High throughput no yes
PINK1_HUMAN [view interactions] High throughput no yes
DICER_HUMAN [view entry] [view interactions] High throughput yes yes
TFCP2_HUMAN [view interactions] High throughput no no
NEK4_HUMAN [view interactions] High throughput no yes
TRIM6_HUMAN [view interactions] High throughput no no
PRD16_HUMAN [view interactions] High throughput no no
ZCH18_HUMAN [view interactions] High throughput no yes
MECOM_HUMAN [view interactions] High throughput no yes
EMC1_HUMAN [view interactions] High throughput no yes
SAP_HUMAN [view interactions] High throughput no yes
SNIP1_HUMAN [view interactions] High throughput no no
CRY1_HUMAN [view interactions] High throughput no yes
ANR55_HUMAN [view interactions] High throughput no yes
VAV_HUMAN [view interactions] High throughput no no
LRC31_HUMAN [view interactions] High throughput no no
RASA1_HUMAN [view interactions] High throughput no yes
NMRL1_HUMAN [view interactions] High throughput no yes
MK07_HUMAN [view interactions] High throughput no yes
ODFP2_HUMAN [view interactions] High throughput no no
RALB_HUMAN [view interactions] High throughput no no
BRD4_HUMAN [view interactions] High throughput no yes
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
RBM45_HUMAN [view interactions] High throughput no yes
PAXI_HUMAN [view interactions] High throughput no yes
SC6A4_HUMAN [view entry] [view interactions] High throughput yes no
MP2K3_HUMAN [view entry] [view interactions] High throughput yes yes
CIC_HUMAN [view interactions] High throughput no yes
KPCE_HUMAN [view entry] [view interactions] High throughput yes yes
UBR5_HUMAN [view interactions] High throughput no no
M3K14_HUMAN [view interactions] High throughput no yes
CFAD_HUMAN [view interactions] High throughput no no
MTA2_HUMAN [view interactions] High throughput no yes
FNDC5_HUMAN [view interactions] High throughput no no
ELK1_HUMAN [view interactions] High throughput no yes
RBM39_HUMAN [view interactions] High throughput no yes
PAK1_HUMAN [view entry] [view interactions] High throughput yes yes
CBX1_HUMAN [view interactions] High throughput no yes
KPCG_HUMAN [view entry] [view interactions] High throughput yes yes
MT21E_HUMAN [view interactions] High throughput no no
KPCZ_HUMAN [view entry] [view interactions] High throughput yes yes
IF16_HUMAN [view interactions] High throughput no no
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
WDR76_HUMAN [view interactions] High throughput no no
HDAC1_HUMAN [view interactions] High throughput no no
KDF1_HUMAN [view interactions] High throughput no yes
CSK_HUMAN [view interactions] High throughput no yes
RIN3_HUMAN [view interactions] High throughput no yes
ACK1_HUMAN [view interactions] High throughput no yes
SPOP_HUMAN [view interactions] High throughput no no
MYLK2_HUMAN [view interactions] High throughput no no
ANDR_HUMAN [view interactions] High throughput no no
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
UFL1_HUMAN [view interactions] High throughput no yes
MSPD2_HUMAN [view interactions] High throughput no yes
DDRGK_HUMAN [view entry] [view interactions] High throughput yes yes
NCBP3_HUMAN [view interactions] High throughput no yes
TRI37_HUMAN [view entry] [view interactions] High throughput yes yes
DJC11_HUMAN [view entry] [view interactions] High throughput yes no
WDR5_HUMAN [view interactions] High throughput no no
MOT11_HUMAN [view interactions] High throughput no no
PAGE4_HUMAN [view interactions] High throughput no no
PPM1E_HUMAN [view entry] [view interactions] High throughput yes yes
NUDC2_HUMAN [view entry] [view interactions] High throughput yes yes
PPM1A_HUMAN [view interactions] High throughput no yes
CD80_HUMAN [view interactions] High throughput no no
GRID2_HUMAN [view entry] [view interactions] High throughput yes no
LCFC1_HUMAN [view interactions] High throughput no no
LRP1_HUMAN [view entry] [view interactions] High throughput yes yes
VCAM1_HUMAN [view interactions] High throughput no no
I13R2_HUMAN [view interactions] High throughput no no
CDK1_HUMAN [view interactions] High throughput no no
OSTM1_HUMAN [view interactions] High throughput no yes
COX15_HUMAN [view interactions] High throughput no yes
ISLR_HUMAN [view interactions] High throughput no no
ODO2_HUMAN [view entry] [view interactions] High throughput yes yes
GLMP_HUMAN [view interactions] High throughput no no
SDHA_HUMAN [view interactions] High throughput no yes
TBC17_HUMAN [view entry] [view interactions] High throughput yes yes
SOAT1_HUMAN [view interactions] High throughput no no
BASI_HUMAN [view entry] [view interactions] High throughput yes no
VDAC1_HUMAN [view entry] [view interactions] High throughput yes yes
SPRTN_HUMAN [view interactions] High throughput no yes
RHG28_HUMAN [view interactions] High throughput no no
BTF3_HUMAN [view interactions] High throughput no yes
BDP1_HUMAN [view interactions] High throughput no no
THB_HUMAN [view interactions] High throughput no no
PMFBP_HUMAN [view interactions] High throughput no yes
FBXW7_HUMAN [view interactions] High throughput no yes
BACE1_HUMAN [view interactions] High throughput no yes
FURIN_HUMAN [view interactions] High throughput no yes
TAU_HUMAN [view entry] [view interactions] High throughput yes yes
TM11B_HUMAN [view interactions] High throughput no no
RD23B_HUMAN [view interactions] High throughput no yes
ACE2_HUMAN [view interactions] High throughput no no
E2F3_HUMAN [view interactions] High throughput no no
MEX3C_HUMAN [view interactions] High throughput no yes
CCNF_HUMAN [view interactions] High throughput no no
NCK2_HUMAN [view entry] [view interactions] High throughput yes yes
ZN363_HUMAN [view interactions] High throughput no yes
CD3Z_HUMAN [view interactions] High throughput no no
HECD1_HUMAN [view interactions] High throughput no yes
DUX4_HUMAN [view interactions] High throughput no no
OXLA_HUMAN [view interactions] High throughput no no
PSN1_HUMAN [view entry] [view interactions] High throughput yes yes
ZEB1_HUMAN [view interactions] High throughput no yes
TBB3_HUMAN [view entry] [view interactions] High throughput yes yes
BAG1_HUMAN [view interactions] High throughput no yes
EZRI_HUMAN [view entry] [view interactions] High throughput yes no
CAPZB_HUMAN [view entry] [view interactions] High throughput yes yes
TBA1A_HUMAN [view entry] [view interactions] High throughput yes yes
PSB10_HUMAN [view interactions] High throughput no no
CFTR_HUMAN [view interactions] High throughput no no
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
ESR1_HUMAN [view interactions] High throughput no no
PTEN_HUMAN [view entry] [view interactions] High throughput yes yes
PHAG1_HUMAN [view interactions] High throughput no yes
UBC_HUMAN [view entry] [view interactions] High throughput yes yes
CBL_HUMAN [view interactions] High throughput no yes
ITA2B_HUMAN [view interactions] High throughput no no
ERBB2_HUMAN [view entry] [view interactions] High throughput yes no
RL7_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK1_HUMAN [view interactions] High throughput no yes
RL37A_HUMAN [view entry] [view interactions] High throughput yes yes
NTRK3_HUMAN [view entry] [view interactions] High throughput yes yes
RL15_HUMAN [view entry] [view interactions] High throughput yes no
TYRO3_HUMAN [view interactions] High throughput no yes
RL10A_HUMAN [view entry] [view interactions] High throughput yes yes
EGFR_HUMAN [view interactions] High throughput no no
RL14_HUMAN [view entry] [view interactions] High throughput yes yes
MK03_HUMAN [view entry] [view interactions] High throughput yes yes
RL31_HUMAN [view entry] [view interactions] High throughput yes yes
RS3A_HUMAN [view entry] [view interactions] High throughput yes yes
ATPB_HUMAN [view interactions] High throughput no yes
RS15A_HUMAN [view entry] [view interactions] High throughput yes yes
C560_HUMAN [view interactions] High throughput no no
RL18_HUMAN [view entry] [view interactions] High throughput yes yes
CH60_HUMAN [view entry] [view interactions] High throughput yes yes
RS23_HUMAN [view entry] [view interactions] High throughput yes yes
DHSD_HUMAN [view interactions] High throughput no yes
RL6_HUMAN [view entry] [view interactions] High throughput yes yes
EFTU_HUMAN [view entry] [view interactions] High throughput yes yes
RS6_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT1_HUMAN [view entry] [view interactions] High throughput yes yes
RS2_HUMAN [view entry] [view interactions] High throughput yes yes
FLOT2_HUMAN [view entry] [view interactions] High throughput yes yes
RL23_HUMAN [view entry] [view interactions] High throughput yes yes
GRP75_HUMAN [view entry] [view interactions] High throughput yes yes
RL11_HUMAN [view entry] [view interactions] High throughput yes yes
PHB1_HUMAN [view entry] [view interactions] High throughput yes yes
RL21_HUMAN [view entry] [view interactions] High throughput yes yes
SDHB_HUMAN [view interactions] High throughput no yes
RL7A_HUMAN [view entry] [view interactions] High throughput yes no
JUN_HUMAN [view interactions] High throughput no yes
RL23A_HUMAN [view entry] [view interactions] High throughput yes yes
HSPB2_HUMAN [view interactions] High throughput no yes
RL4_HUMAN [view entry] [view interactions] High throughput yes yes
RD3_HUMAN [view interactions] High throughput no no
RL19_HUMAN [view entry] [view interactions] High throughput yes yes
LITD1_HUMAN [view interactions] High throughput no no
RS4X_HUMAN [view entry] [view interactions] High throughput yes yes
TCTP_HUMAN [view entry] [view interactions] High throughput yes yes
RS3_HUMAN [view entry] [view interactions] High throughput yes yes
CD177_HUMAN [view interactions] High throughput no no
RL5_HUMAN [view entry] [view interactions] High throughput yes yes
DNM1L_HUMAN [view entry] [view interactions] High throughput yes yes
RS24_HUMAN [view entry] [view interactions] High throughput yes yes
EGLN_HUMAN [view interactions] High throughput no no
RL9_HUMAN [view entry] [view interactions] High throughput yes yes
ITM2B_HUMAN [view interactions] High throughput no yes
RS8_HUMAN [view entry] [view interactions] High throughput yes no
BMI1_HUMAN [view interactions] High throughput no yes
RS21_HUMAN [view entry] [view interactions] High throughput yes yes
CNDD3_HUMAN [view interactions] High throughput no no
RSSA_HUMAN [view entry] [view interactions] High throughput yes yes
IKBA_HUMAN [view interactions] High throughput no yes
RS28_HUMAN [view entry] [view interactions] High throughput yes yes
NEMO_HUMAN [view interactions] High throughput no yes
RS19_HUMAN [view entry] [view interactions] High throughput yes no
M3K1_HUMAN [view interactions] High throughput no yes
RT16_HUMAN [view interactions] High throughput no yes
M3K3_HUMAN [view interactions] High throughput no no
ELAV1_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK1_HUMAN [view interactions] High throughput no yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
RIPK3_HUMAN [view interactions] High throughput no no
LEG3_HUMAN [view interactions] High throughput no yes
TNR1A_HUMAN [view interactions] High throughput no yes
RPN1_HUMAN [view entry] [view interactions] High throughput yes yes
TNR1B_HUMAN [view interactions] High throughput no no
GRHPR_HUMAN [view entry] [view interactions] High throughput yes no
TRADD_HUMAN [view interactions] High throughput no yes
K2C1_HUMAN [view interactions] High throughput no no
TRAF1_HUMAN [view interactions] High throughput no no
LMNA_HUMAN [view entry] [view interactions] High throughput yes yes
TRAF2_HUMAN [view interactions] High throughput no yes
RT34_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
NPTN_HUMAN [view entry] [view interactions] High throughput yes yes
TONSL_HUMAN [view interactions] High throughput no no
ANX11_HUMAN [view entry] [view interactions] High throughput yes yes
HDGF_HUMAN [view interactions] High throughput no yes
VA0D1_HUMAN [view entry] [view interactions] High throughput yes yes
CAND1_HUMAN [view entry] [view interactions] High throughput yes no
HNRPU_HUMAN [view interactions] High throughput no yes
CUL1_HUMAN [view interactions] High throughput no yes
NDUS4_HUMAN [view interactions] High throughput no yes
CUL4A_HUMAN [view interactions] High throughput no no
PMM2_HUMAN [view interactions] High throughput no no
DCNL1_HUMAN [view interactions] High throughput no yes
MCAT_HUMAN [view interactions] High throughput no yes
CSN5_HUMAN [view interactions] High throughput no yes
SCMC1_HUMAN [view interactions] High throughput no no
CUL2_HUMAN [view interactions] High throughput no yes
ADT1_HUMAN [view entry] [view interactions] High throughput yes yes
CUL4B_HUMAN [view interactions] High throughput no yes
TOM20_HUMAN [view entry] [view interactions] High throughput yes yes
CSN6_HUMAN [view interactions] High throughput no yes
VDAC2_HUMAN [view entry] [view interactions] High throughput yes yes
CUL3_HUMAN [view entry] [view interactions] High throughput yes yes
ATPMK_HUMAN [view interactions] High throughput no no
CUL5_HUMAN [view entry] [view interactions] High throughput yes yes
VDAC3_HUMAN [view entry] [view interactions] High throughput yes yes
5HT7R_HUMAN [view entry] [view interactions] High throughput yes yes
SC61B_HUMAN [view interactions] High throughput no yes
ESR2_HUMAN [view interactions] High throughput no no
ATPO_HUMAN [view interactions] High throughput no yes
NFKB1_HUMAN [view interactions] High throughput no yes
COX5A_HUMAN [view entry] [view interactions] High throughput yes yes
FAKD3_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
B9D1_HUMAN [view interactions] High throughput no yes
CY1_HUMAN [view entry] [view interactions] High throughput yes yes
ECSIT_HUMAN [view interactions] High throughput no yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
ATD3A_HUMAN [view entry] [view interactions] High throughput yes yes
PSA3_HUMAN [view interactions] High throughput no no
TIFAB_HUMAN [view interactions] High throughput no no
ATPG_HUMAN [view interactions] High throughput no yes
A2MG_HUMAN [view interactions] High throughput no yes
AT5L2_HUMAN [view interactions] High throughput no no
ADT3_HUMAN [view entry] [view interactions] High throughput yes yes
ATP5L_HUMAN [view interactions] High throughput no yes
COX14_HUMAN [view interactions] High throughput no yes
COX6C_HUMAN [view entry] [view interactions] High throughput yes yes
COX1_HUMAN [view interactions] High throughput no yes
MDHM_HUMAN [view entry] [view interactions] High throughput yes yes
COXM1_HUMAN [view entry] [view interactions] High throughput yes yes
ATX1_HUMAN [view interactions] High throughput no yes
RDH13_HUMAN [view interactions] High throughput no no
RBM47_HUMAN [view interactions] High throughput no yes
RM40_HUMAN [view interactions] High throughput no yes
TMM70_HUMAN [view interactions] High throughput no yes
RM46_HUMAN [view interactions] High throughput no yes
LEG9_HUMAN [view interactions] High throughput no yes
RM48_HUMAN [view interactions] High throughput no yes
COIL_HUMAN [view interactions] High throughput no yes
SIM20_HUMAN [view interactions] High throughput no yes
COX8A_HUMAN [view interactions] High throughput no yes
SURF1_HUMAN [view interactions] High throughput no yes
ODPA_HUMAN [view entry] [view interactions] High throughput yes yes
TIM21_HUMAN [view interactions] High throughput no yes
TRAP1_HUMAN [view entry] [view interactions] High throughput yes yes
TM223_HUMAN [view interactions] High throughput no yes
SYNPO_HUMAN [view entry] [view interactions] High throughput yes no
NECD_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
NOP56_HUMAN [view interactions] High throughput no yes
SHIP2_HUMAN [view interactions] High throughput no yes
FBX6_HUMAN [view interactions] High throughput no yes
LIPC_HUMAN [view interactions] High throughput no no
IF4A3_HUMAN [view entry] [view interactions] High throughput yes yes
SMUF1_HUMAN [view interactions] High throughput no yes
FINC_HUMAN [view interactions] High throughput no yes
NOS2_HUMAN [view interactions] High throughput no yes
UBL4A_HUMAN [view entry] [view interactions] High throughput yes yes
ITA4_HUMAN [view interactions] High throughput no no
CLN3_HUMAN [view interactions] High throughput no no
CLN5_HUMAN [view interactions] High throughput no yes
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
PLCB1_HUMAN [view entry] [view interactions] High throughput yes yes
ADRB2_HUMAN [view entry] [view interactions] High throughput yes no
BAG3_HUMAN [view entry] [view interactions] High throughput yes no
TADBP_HUMAN [view interactions] High throughput no yes
CXA1_HUMAN [view entry] [view interactions] High throughput yes yes
PRKN_HUMAN [view entry] [view interactions] High throughput yes yes
ASB3_HUMAN [view interactions] High throughput no yes
ASB6_HUMAN [view interactions] High throughput no yes
ASB10_HUMAN [view interactions] High throughput no no
ASB14_HUMAN [view interactions] High throughput no no
ASB18_HUMAN [view interactions] High throughput no no
SMUF2_HUMAN [view interactions] High throughput no yes
AP2M1_HUMAN [view entry] [view interactions] High throughput yes yes
ERBB3_HUMAN [view interactions] High throughput no yes
ERR2_HUMAN [view interactions] High throughput no no
CDC37_HUMAN [view interactions] High throughput no yes
LGR4_HUMAN [view interactions] High throughput no yes
STAU1_HUMAN [view entry] [view interactions] High throughput yes yes
P53_HUMAN [view interactions] High throughput no no
HUWE1_HUMAN [view interactions] High throughput no yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
CUL7_HUMAN [view interactions] High throughput no yes
OBSL1_HUMAN [view interactions] High throughput no yes
EED_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
GAN_HUMAN [view interactions] High throughput no yes
SKI_HUMAN [view interactions] High throughput no yes
PODO_HUMAN [view interactions] High throughput no no
MCM2_HUMAN [view interactions] High throughput no no
MCM5_HUMAN [view interactions] High throughput no no
MERL_HUMAN [view interactions] High throughput no yes
KSR1_HUMAN [view interactions] High throughput no yes
RN126_HUMAN [view interactions] High throughput no yes
U2AF2_HUMAN [view interactions] High throughput no yes
RC3H1_HUMAN [view interactions] High throughput no yes
AIFM1_HUMAN [view entry] [view interactions] High throughput yes no
WWP2_HUMAN [view interactions] High throughput no no
ZN746_HUMAN [view interactions] High throughput no no
FACD2_HUMAN [view interactions] High throughput no no
CYLD_HUMAN [view entry] [view interactions] High throughput yes yes
TRI25_HUMAN [view interactions] High throughput no yes
YAP1_HUMAN [view interactions] High throughput no yes
ATX3_HUMAN [view interactions] High throughput no yes
ZN598_HUMAN [view interactions] High throughput no no
GLUT4_HUMAN [view interactions] High throughput no no
FBX7_HUMAN [view interactions] High throughput no yes
AGO1_HUMAN [view interactions] High throughput no no
DX39B_HUMAN [view interactions] High throughput no no
AGO2_HUMAN [view interactions] High throughput no yes
CTNB1_HUMAN [view entry] [view interactions] High throughput yes yes
AGO4_HUMAN [view interactions] High throughput no no
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
DLG4_HUMAN [view entry] [view interactions] High throughput yes yes
IGF1R_HUMAN [view entry] [view interactions] High throughput yes yes
PCBP1_HUMAN [view entry] [view interactions] High throughput yes yes
MLP3A_HUMAN [view entry] [view interactions] High throughput yes yes
TGFB1_HUMAN [view interactions] High throughput no no
MLP3B_HUMAN [view interactions] High throughput no yes
HIF1N_HUMAN [view interactions] High throughput no yes
RAB28_HUMAN [view interactions] Computational no yes
ADT4_HUMAN [view entry] [view interactions] Computational yes no
PPIF_HUMAN [view interactions] Computational no no
ERCC2_HUMAN [view interactions] Computational no yes
TSPO_HUMAN [view interactions] Computational no yes
MMS19_HUMAN [view interactions] Computational no yes
CIAO1_HUMAN [view interactions] Computational no yes
CIA2B_HUMAN [view interactions] Computational no yes
PPID_HUMAN [view entry] [view interactions] Computational yes yes