KPCE_HUMAN
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration. In HeLa cells, contributes to hepatocyte growth factor (HGF)-induced cell migration, and in human corneal epithelial cells, plays a critical role in wound healing after activation by HGF. During cytokinesis, forms a complex with YWHAB, which is crucial for daughter cell separation, and facilitates abscission by a mechanism which may implicate the regulation of RHOA. In cardiac myocytes, regulates myofilament function and excitation coupling at the Z-lines, where it is indirectly associated with F-actin via interaction with COPB1. During endothelin-induced cardiomyocyte hypertrophy, mediates activation of PTK2/FAK, which is critical for cardiomyocyte survival and regulation of sarcomere length. Plays a role in the pathogenesis of dilated cardiomyopathy via persistent phosphorylation of troponin I (TNNI3). Involved in nerve growth factor (NFG)-induced neurite outgrowth and neuron morphological change independently of its kinase activity, by inhibition of RHOA pathway, activation of CDC42 and cytoskeletal rearrangement. May be involved in presynaptic facilitation by mediating phorbol ester-induced synaptic potentiation. Phosphorylates gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), which reduces the response of GABA receptors to ethanol and benzodiazepines and may mediate acute tolerance to the intoxicating effects of ethanol. Upon PMA treatment, phosphorylates the capsaicin- and heat-activated cation channel TRPV1, which is required for bradykinin-induced sensitization of the heat response in nociceptive neurons. Is able to form a complex with PDLIM5 and N-type calcium channel, and may enhance channel activities and potentiates fast synaptic transmission by phosphorylating the pore-forming alpha subunit CACNA1B (CaV2.2). In prostate cancer cells, interacts with and phosphorylates STAT3, which increases DNA-binding and transcriptional activity of STAT3 and seems to be essential for prostate cancer cell invasion. Downstream of TLR4, plays an important role in the lipopolysaccharide (LPS)-induced immune response by phosphorylating and activating TICAM2/TRAM, which in turn activates the transcription factor IRF3 and subsequent cytokines production. In differentiating erythroid progenitors, is regulated by EPO and controls the protection against the TNFSF10/TRAIL-mediated apoptosis, via BCL2. May be involved in the regulation of the insulin-induced phosphorylation and activation of AKT1. Phosphorylates NLRP5/MATER and may thereby modulate AKT pathway activation in cumulus cells (PubMed). [View more on UniProt]
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No data found.
ELM instance | Name | Type | Start | End | Partner |
---|---|---|---|---|---|
ELMI002989 | LIG_14-3-3_CanoR_1 | LIG | 343 | 348 | - |
ELMI003043 | LIG_14-3-3_CanoR_1 | LIG | 364 | 370 | - |
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in KPCE_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 33.0935 | 4 | yes |
GO:0032555 | purine ribonucleotide binding | 33.0935 | 4 | yes |
GO:0019900 | kinase binding | 31.6547 | 4 | no |
GO:0035639 | purine ribonucleoside triphosphate binding | 30.9353 | 4 | yes |
GO:0019901 | protein kinase binding | 30.9353 | 5 | no |
GO:0003723 | RNA binding | 29.4964 | 4 | no |
GO:0030554 | adenyl nucleotide binding | 27.3381 | 5 | yes |
GO:0032559 | adenyl ribonucleotide binding | 27.3381 | 5 | yes |
GO:0046872 | metal ion binding | 26.6187 | 4 | yes |
GO:0005524 | ATP binding | 25.1799 | 5 | yes |
GO:0003779 | actin binding | 15.8273 | 4 | yes |
GO:0016301 | kinase activity | 14.3885 | 4 | yes |
GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 14.3885 | 4 | yes |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | 13.6691 | 4 | yes |
GO:0004674 | protein serine/threonine kinase activity | 12.2302 | 4 | yes |
GO:0106310 | protein serine kinase activity | 11.5108 | 4 | yes |
GO:0004697 | protein kinase C activity | 5.0360 | 5 | yes |
GO:0004698 | calcium-dependent protein kinase C activity | 5.0360 | 6 | yes |
GO:0009931 | calcium-dependent protein serine/threonine kinase activity | 5.0360 | 5 | yes |
GO:0010857 | calcium-dependent protein kinase activity | 5.0360 | 4 | yes |
GO:0004699 | calcium-independent protein kinase C activity | 2.1583 | 6 | yes |
GO:0003785 | actin monomer binding | 1.4388 | 5 | yes |
GO:0035276 | ethanol binding | 1.4388 | 4 | yes |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in KPCE_HUMAN |
---|---|---|---|---|
GO:0048522 | positive regulation of cellular process | 60.4317 | 4 | yes |
GO:0060255 | regulation of macromolecule metabolic process | 58.9928 | 4 | yes |
GO:0048523 | negative regulation of cellular process | 58.2734 | 4 | yes |
GO:0080090 | regulation of primary metabolic process | 56.8345 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 55.3957 | 4 | yes |
GO:0051171 | regulation of nitrogen compound metabolic process | 55.3957 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 47.4820 | 4 | yes |
GO:0010646 | regulation of cell communication | 46.0432 | 4 | yes |
GO:0051246 | regulation of protein metabolic process | 46.0432 | 5 | yes |
GO:0009893 | positive regulation of metabolic process | 46.0432 | 4 | yes |
GO:0009966 | regulation of signal transduction | 43.1655 | 4 | yes |
GO:0006996 | organelle organization | 42.4460 | 4 | no |
GO:0010468 | regulation of gene expression | 41.7266 | 5 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 40.2878 | 5 | no |
GO:0031325 | positive regulation of cellular metabolic process | 37.4101 | 5 | yes |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 37.4101 | 5 | no |
GO:0010941 | regulation of cell death | 35.9712 | 4 | no |
GO:0051049 | regulation of transport | 35.2518 | 4 | yes |
GO:0009892 | negative regulation of metabolic process | 35.2518 | 4 | yes |
GO:0071310 | cellular response to organic substance | 34.5324 | 4 | yes |
GO:0009889 | regulation of biosynthetic process | 34.5324 | 4 | no |
GO:0010556 | regulation of macromolecule biosynthetic process | 34.5324 | 5 | no |
GO:0043067 | regulation of programmed cell death | 34.5324 | 5 | no |
GO:0022607 | cellular component assembly | 33.8129 | 4 | no |
GO:0031326 | regulation of cellular biosynthetic process | 33.8129 | 5 | no |
GO:0042981 | regulation of apoptotic process | 33.8129 | 6 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 33.0935 | 5 | yes |
GO:1902531 | regulation of intracellular signal transduction | 32.3741 | 5 | yes |
GO:0031399 | regulation of protein modification process | 31.6547 | 6 | yes |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 31.6547 | 5 | yes |
GO:0019219 | regulation of nucleobase-containing compound metabolic process | 31.6547 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 31.6547 | 6 | no |
GO:0019220 | regulation of phosphate metabolic process | 30.9353 | 6 | yes |
GO:0033043 | regulation of organelle organization | 30.9353 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 30.9353 | 4 | yes |
GO:0051174 | regulation of phosphorus metabolic process | 30.9353 | 5 | yes |
GO:0023056 | positive regulation of signaling | 30.2158 | 4 | yes |
GO:0006796 | phosphate-containing compound metabolic process | 30.2158 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 29.4964 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 28.7770 | 4 | yes |
GO:0031324 | negative regulation of cellular metabolic process | 28.7770 | 5 | no |
GO:0042325 | regulation of phosphorylation | 28.0576 | 7 | yes |
GO:0036211 | protein modification process | 27.3381 | 4 | yes |
GO:0043412 | macromolecule modification | 27.3381 | 4 | yes |
GO:0060341 | regulation of cellular localization | 27.3381 | 4 | yes |
GO:0043085 | positive regulation of catalytic activity | 27.3381 | 4 | no |
GO:0044087 | regulation of cellular component biogenesis | 26.6187 | 4 | yes |
GO:0051252 | regulation of RNA metabolic process | 26.6187 | 5 | no |
GO:0007010 | cytoskeleton organization | 26.6187 | 5 | no |
GO:0051338 | regulation of transferase activity | 25.8993 | 4 | no |
GO:0042127 | regulation of cell population proliferation | 25.8993 | 4 | no |
GO:0009967 | positive regulation of signal transduction | 25.8993 | 5 | yes |
GO:0051130 | positive regulation of cellular component organization | 25.1799 | 5 | yes |
GO:0008104 | protein localization | 25.1799 | 4 | no |
GO:0001932 | regulation of protein phosphorylation | 25.1799 | 7 | yes |
GO:0080134 | regulation of response to stress | 24.4604 | 4 | yes |
GO:0060548 | negative regulation of cell death | 24.4604 | 5 | no |
GO:0045595 | regulation of cell differentiation | 23.7410 | 4 | no |
GO:0043069 | negative regulation of programmed cell death | 23.7410 | 6 | no |
GO:0009894 | regulation of catabolic process | 23.7410 | 4 | yes |
GO:0010243 | response to organonitrogen compound | 23.7410 | 4 | yes |
GO:0051050 | positive regulation of transport | 23.0216 | 4 | yes |
GO:1901701 | cellular response to oxygen-containing compound | 23.0216 | 4 | yes |
GO:0006355 | regulation of DNA-templated transcription | 23.0216 | 6 | no |
GO:0071702 | organic substance transport | 23.0216 | 4 | no |
GO:1903506 | regulation of nucleic acid-templated transcription | 23.0216 | 7 | no |
GO:2001141 | regulation of RNA biosynthetic process | 23.0216 | 6 | no |
GO:0010628 | positive regulation of gene expression | 23.0216 | 6 | no |
GO:0043549 | regulation of kinase activity | 23.0216 | 5 | no |
GO:0043066 | negative regulation of apoptotic process | 23.0216 | 7 | no |
GO:0032880 | regulation of protein localization | 22.3022 | 5 | yes |
GO:0051248 | negative regulation of protein metabolic process | 22.3022 | 6 | yes |
GO:0051094 | positive regulation of developmental process | 21.5827 | 4 | no |
GO:0071705 | nitrogen compound transport | 21.5827 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 21.5827 | 6 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 21.5827 | 7 | no |
GO:0022603 | regulation of anatomical structure morphogenesis | 21.5827 | 4 | no |
GO:0043933 | protein-containing complex organization | 20.8633 | 4 | no |
GO:0048585 | negative regulation of response to stimulus | 20.8633 | 4 | no |
GO:0051336 | regulation of hydrolase activity | 20.8633 | 4 | no |
GO:0031344 | regulation of cell projection organization | 20.1439 | 5 | no |
GO:0051129 | negative regulation of cellular component organization | 20.1439 | 5 | no |
GO:0010648 | negative regulation of cell communication | 20.1439 | 5 | no |
GO:0023057 | negative regulation of signaling | 20.1439 | 4 | no |
GO:0042327 | positive regulation of phosphorylation | 20.1439 | 8 | no |
GO:0045859 | regulation of protein kinase activity | 20.1439 | 6 | no |
GO:0014070 | response to organic cyclic compound | 19.4245 | 4 | yes |
GO:1902533 | positive regulation of intracellular signal transduction | 19.4245 | 6 | yes |
GO:2000145 | regulation of cell motility | 19.4245 | 4 | yes |
GO:0010638 | positive regulation of organelle organization | 18.7050 | 6 | yes |
GO:0051493 | regulation of cytoskeleton organization | 18.7050 | 6 | yes |
GO:0016310 | phosphorylation | 17.9856 | 5 | yes |
GO:0030334 | regulation of cell migration | 17.9856 | 5 | yes |
GO:0043254 | regulation of protein-containing complex assembly | 17.9856 | 5 | yes |
GO:0050776 | regulation of immune response | 17.2662 | 4 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 17.2662 | 5 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 17.2662 | 4 | yes |
GO:0043408 | regulation of MAPK cascade | 16.5468 | 6 | yes |
GO:1902903 | regulation of supramolecular fiber organization | 16.5468 | 5 | yes |
GO:0002684 | positive regulation of immune system process | 16.5468 | 4 | yes |
GO:0006468 | protein phosphorylation | 16.5468 | 5 | yes |
GO:0031400 | negative regulation of protein modification process | 15.8273 | 7 | yes |
GO:0034762 | regulation of transmembrane transport | 15.8273 | 4 | yes |
GO:1903829 | positive regulation of protein localization | 15.1079 | 5 | yes |
GO:0018193 | peptidyl-amino acid modification | 14.3885 | 5 | yes |
GO:0043269 | regulation of ion transport | 14.3885 | 5 | yes |
GO:0030335 | positive regulation of cell migration | 13.6691 | 6 | yes |
GO:0040017 | positive regulation of locomotion | 13.6691 | 4 | yes |
GO:2000147 | positive regulation of cell motility | 13.6691 | 5 | yes |
GO:0009896 | positive regulation of catabolic process | 13.6691 | 5 | yes |
GO:0030155 | regulation of cell adhesion | 12.9496 | 4 | yes |
GO:0032970 | regulation of actin filament-based process | 12.9496 | 4 | yes |
GO:0033993 | response to lipid | 12.9496 | 4 | yes |
GO:0034765 | regulation of ion transmembrane transport | 12.9496 | 5 | yes |
GO:0044089 | positive regulation of cellular component biogenesis | 12.9496 | 5 | yes |
GO:0070201 | regulation of establishment of protein localization | 12.9496 | 6 | yes |
GO:0006915 | apoptotic process | 12.9496 | 4 | yes |
GO:0032271 | regulation of protein polymerization | 12.2302 | 6 | yes |
GO:0032870 | cellular response to hormone stimulus | 12.2302 | 4 | yes |
GO:0051223 | regulation of protein transport | 12.2302 | 5 | yes |
GO:1904062 | regulation of cation transmembrane transport | 12.2302 | 6 | yes |
GO:0032956 | regulation of actin cytoskeleton organization | 11.5108 | 5 | yes |
GO:0043410 | positive regulation of MAPK cascade | 11.5108 | 7 | yes |
GO:0050778 | positive regulation of immune response | 11.5108 | 5 | yes |
GO:0051726 | regulation of cell cycle | 11.5108 | 4 | yes |
GO:0045785 | positive regulation of cell adhesion | 10.7914 | 5 | yes |
GO:0071396 | cellular response to lipid | 10.7914 | 5 | yes |
GO:0010959 | regulation of metal ion transport | 10.0719 | 6 | yes |
GO:0032535 | regulation of cellular component size | 10.0719 | 4 | yes |
GO:0051051 | negative regulation of transport | 10.0719 | 4 | yes |
GO:0051222 | positive regulation of protein transport | 10.0719 | 5 | yes |
GO:1904951 | positive regulation of establishment of protein localization | 10.0719 | 6 | yes |
GO:0018105 | peptidyl-serine phosphorylation | 9.3525 | 6 | yes |
GO:0018209 | peptidyl-serine modification | 9.3525 | 6 | yes |
GO:0022898 | regulation of transmembrane transporter activity | 9.3525 | 4 | yes |
GO:0031334 | positive regulation of protein-containing complex assembly | 9.3525 | 6 | yes |
GO:0051495 | positive regulation of cytoskeleton organization | 9.3525 | 7 | yes |
GO:0110053 | regulation of actin filament organization | 9.3525 | 6 | yes |
GO:1902905 | positive regulation of supramolecular fiber organization | 9.3525 | 6 | yes |
GO:0050806 | positive regulation of synaptic transmission | 8.6331 | 5 | yes |
GO:0097305 | response to alcohol | 8.6331 | 4 | yes |
GO:1905475 | regulation of protein localization to membrane | 8.6331 | 6 | yes |
GO:0019216 | regulation of lipid metabolic process | 7.9137 | 5 | yes |
GO:0032412 | regulation of ion transmembrane transporter activity | 7.9137 | 5 | yes |
GO:0051046 | regulation of secretion | 7.9137 | 5 | yes |
GO:1904375 | regulation of protein localization to cell periphery | 7.9137 | 6 | yes |
GO:0006109 | regulation of carbohydrate metabolic process | 7.9137 | 5 | yes |
GO:0010675 | regulation of cellular carbohydrate metabolic process | 7.1942 | 5 | yes |
GO:0045834 | positive regulation of lipid metabolic process | 7.1942 | 5 | yes |
GO:0050730 | regulation of peptidyl-tyrosine phosphorylation | 7.1942 | 8 | yes |
GO:0051924 | regulation of calcium ion transport | 7.1942 | 7 | yes |
GO:0062012 | regulation of small molecule metabolic process | 7.1942 | 4 | yes |
GO:1903169 | regulation of calcium ion transmembrane transport | 7.1942 | 7 | yes |
GO:1903530 | regulation of secretion by cell | 7.1942 | 4 | yes |
GO:0010632 | regulation of epithelial cell migration | 6.4748 | 4 | yes |
GO:0010634 | positive regulation of epithelial cell migration | 6.4748 | 5 | yes |
GO:0010810 | regulation of cell-substrate adhesion | 6.4748 | 5 | yes |
GO:0030832 | regulation of actin filament length | 6.4748 | 5 | yes |
GO:0031396 | regulation of protein ubiquitination | 6.4748 | 8 | yes |
GO:0032273 | positive regulation of protein polymerization | 6.4748 | 7 | yes |
GO:1901654 | response to ketone | 6.4748 | 4 | yes |
GO:1903076 | regulation of protein localization to plasma membrane | 6.4748 | 7 | yes |
GO:1903320 | regulation of protein modification by small protein conjugation or removal | 6.4748 | 7 | yes |
GO:1905477 | positive regulation of protein localization to membrane | 6.4748 | 6 | yes |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 6.4748 | 4 | yes |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 6.4748 | 4 | yes |
GO:0008064 | regulation of actin polymerization or depolymerization | 6.4748 | 6 | yes |
GO:0030833 | regulation of actin filament polymerization | 5.7554 | 7 | yes |
GO:0036293 | response to decreased oxygen levels | 5.7554 | 4 | yes |
GO:0045471 | response to ethanol | 5.7554 | 5 | yes |
GO:0062013 | positive regulation of small molecule metabolic process | 5.7554 | 5 | yes |
GO:0010811 | positive regulation of cell-substrate adhesion | 5.0360 | 6 | yes |
GO:0031397 | negative regulation of protein ubiquitination | 5.0360 | 9 | yes |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 5.0360 | 6 | yes |
GO:0043271 | negative regulation of ion transport | 5.0360 | 5 | yes |
GO:0045787 | positive regulation of cell cycle | 5.0360 | 5 | yes |
GO:0045913 | positive regulation of carbohydrate metabolic process | 5.0360 | 5 | yes |
GO:0051047 | positive regulation of secretion | 5.0360 | 5 | yes |
GO:0051282 | regulation of sequestering of calcium ion | 5.0360 | 4 | yes |
GO:1901655 | cellular response to ketone | 5.0360 | 5 | yes |
GO:1903034 | regulation of response to wounding | 5.0360 | 5 | yes |
GO:1903078 | positive regulation of protein localization to plasma membrane | 5.0360 | 7 | yes |
GO:1903321 | negative regulation of protein modification by small protein conjugation or removal | 5.0360 | 8 | yes |
GO:1904377 | positive regulation of protein localization to cell periphery | 5.0360 | 6 | yes |
GO:0010564 | regulation of cell cycle process | 5.0360 | 5 | yes |
GO:0010676 | positive regulation of cellular carbohydrate metabolic process | 4.3165 | 6 | yes |
GO:0034763 | negative regulation of transmembrane transport | 4.3165 | 5 | yes |
GO:0036294 | cellular response to decreased oxygen levels | 4.3165 | 5 | yes |
GO:0042116 | macrophage activation | 4.3165 | 4 | yes |
GO:0043279 | response to alkaloid | 4.3165 | 5 | yes |
GO:0046883 | regulation of hormone secretion | 4.3165 | 4 | yes |
GO:0050708 | regulation of protein secretion | 4.3165 | 5 | yes |
GO:0051279 | regulation of release of sequestered calcium ion into cytosol | 4.3165 | 5 | yes |
GO:0061041 | regulation of wound healing | 4.3165 | 6 | yes |
GO:0071453 | cellular response to oxygen levels | 4.3165 | 4 | yes |
GO:1903532 | positive regulation of secretion by cell | 4.3165 | 5 | yes |
GO:0010565 | regulation of cellular ketone metabolic process | 3.5971 | 5 | yes |
GO:0010762 | regulation of fibroblast migration | 3.5971 | 6 | yes |
GO:0010763 | positive regulation of fibroblast migration | 3.5971 | 7 | yes |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | 3.5971 | 4 | yes |
GO:0032410 | negative regulation of transporter activity | 3.5971 | 4 | yes |
GO:0034766 | negative regulation of ion transmembrane transport | 3.5971 | 6 | yes |
GO:0038093 | Fc receptor signaling pathway | 3.5971 | 5 | yes |
GO:0050714 | positive regulation of protein secretion | 3.5971 | 6 | yes |
GO:0050796 | regulation of insulin secretion | 3.5971 | 6 | yes |
GO:0050994 | regulation of lipid catabolic process | 3.5971 | 5 | yes |
GO:0071456 | cellular response to hypoxia | 3.5971 | 4 | yes |
GO:0090068 | positive regulation of cell cycle process | 3.5971 | 6 | yes |
GO:0090087 | regulation of peptide transport | 3.5971 | 5 | yes |
GO:0090276 | regulation of peptide hormone secretion | 3.5971 | 5 | yes |
GO:0097306 | cellular response to alcohol | 3.5971 | 5 | yes |
GO:1904063 | negative regulation of cation transmembrane transport | 3.5971 | 7 | yes |
GO:0002791 | regulation of peptide secretion | 3.5971 | 6 | yes |
GO:0032024 | positive regulation of insulin secretion | 2.8777 | 7 | yes |
GO:0032413 | negative regulation of ion transmembrane transporter activity | 2.8777 | 5 | yes |
GO:0035641 | locomotory exploration behavior | 2.8777 | 4 | yes |
GO:0038094 | Fc-gamma receptor signaling pathway | 2.8777 | 6 | yes |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 2.8777 | 4 | yes |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 2.8777 | 7 | yes |
GO:0046887 | positive regulation of hormone secretion | 2.8777 | 5 | yes |
GO:0050996 | positive regulation of lipid catabolic process | 2.8777 | 6 | yes |
GO:0051302 | regulation of cell division | 2.8777 | 4 | yes |
GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus | 2.8777 | 7 | yes |
GO:0090277 | positive regulation of peptide hormone secretion | 2.8777 | 6 | yes |
GO:0090303 | positive regulation of wound healing | 2.8777 | 6 | yes |
GO:1903036 | positive regulation of response to wounding | 2.8777 | 5 | yes |
GO:0002221 | pattern recognition receptor signaling pathway | 2.8777 | 4 | yes |
GO:0002431 | Fc receptor mediated stimulatory signaling pathway | 2.8777 | 5 | yes |
GO:0002793 | positive regulation of peptide secretion | 2.8777 | 6 | yes |
GO:0014072 | response to isoquinoline alkaloid | 2.1583 | 5 | yes |
GO:0030838 | positive regulation of actin filament polymerization | 2.1583 | 7 | yes |
GO:0032228 | regulation of synaptic transmission, GABAergic | 2.1583 | 6 | yes |
GO:0032465 | regulation of cytokinesis | 2.1583 | 5 | yes |
GO:0032467 | positive regulation of cytokinesis | 2.1583 | 6 | yes |
GO:0034694 | response to prostaglandin | 2.1583 | 4 | yes |
GO:0034695 | response to prostaglandin E | 2.1583 | 5 | yes |
GO:0043278 | response to morphine | 2.1583 | 6 | yes |
GO:0051781 | positive regulation of cell division | 2.1583 | 5 | yes |
GO:0071379 | cellular response to prostaglandin stimulus | 2.1583 | 5 | yes |
GO:0071380 | cellular response to prostaglandin E stimulus | 2.1583 | 6 | yes |
GO:0002028 | regulation of sodium ion transport | 2.1583 | 7 | yes |
GO:0002224 | toll-like receptor signaling pathway | 2.1583 | 5 | yes |
GO:0010766 | negative regulation of sodium ion transport | 1.4388 | 6 | yes |
GO:0032230 | positive regulation of synaptic transmission, GABAergic | 1.4388 | 6 | yes |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.4388 | 6 | yes |
GO:0035668 | TRAM-dependent toll-like receptor signaling pathway | 1.4388 | 7 | yes |
GO:0035669 | TRAM-dependent toll-like receptor 4 signaling pathway | 1.4388 | 7 | yes |
GO:0070255 | regulation of mucus secretion | 1.4388 | 4 | yes |
GO:0070257 | positive regulation of mucus secretion | 1.4388 | 5 | yes |
GO:0071361 | cellular response to ethanol | 1.4388 | 6 | yes |
GO:1902305 | regulation of sodium ion transmembrane transport | 1.4388 | 7 | yes |
GO:1902306 | negative regulation of sodium ion transmembrane transport | 1.4388 | 7 | yes |
GO:2000649 | regulation of sodium ion transmembrane transporter activity | 1.4388 | 6 | yes |
GO:2000650 | negative regulation of sodium ion transmembrane transporter activity | 1.4388 | 6 | yes |
GO:2001029 | regulation of cellular glucuronidation | 1.4388 | 6 | yes |
GO:2001031 | positive regulation of cellular glucuronidation | 1.4388 | 6 | yes |
GO:0002275 | myeloid cell activation involved in immune response | 1.4388 | 4 | yes |
GO:0002281 | macrophage activation involved in immune response | 1.4388 | 5 | yes |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 1.4388 | 6 | yes |
Disease
Term | Name | % | Distance from top the of the tree | Annotated in KPCE_HUMAN |
---|---|---|---|---|
DOID:0050700 | cardiomyopathy | 5.0360 | 4 | no |
DOID:0060036 | intrinsic cardiomyopathy | 5.0360 | 5 | no |
DOID:114 | heart disease | 5.0360 | 3 | no |
DOID:12930 | dilated cardiomyopathy | 4.3165 | 6 | no |
DOID:0050155 | sensory system disease | 2.1583 | 3 | no |
DOID:612 | primary immunodeficiency disease | 1.4388 | 3 | no |
DOID:5614 | eye disease | 1.4388 | 4 | no |
DOID:0050539 | Charcot-Marie-Tooth disease type 2 | 1.4388 | 7 | no |
DOID:10595 | Charcot-Marie-Tooth disease | 1.4388 | 6 | no |
DOID:440 | neuromuscular disease | 1.4388 | 5 | no |
DOID:574 | peripheral nervous system disease | 1.4388 | 3 | no |
DOID:870 | neuropathy | 1.4388 | 4 | no |
DOID:0080326 | familial hypertrophic cardiomyopathy | 1.4388 | 7 | no |
DOID:11984 | hypertrophic cardiomyopathy | 1.4388 | 6 | no |
DOID:0080000 | muscular disease | 1.4388 | 3 | no |
DOID:423 | myopathy | 1.4388 | 5 | no |
DOID:66 | muscle tissue disease | 1.4388 | 4 | no |
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
BRAF_HUMAN | [view interactions] | Low throughput | no | yes |
KS6A2_HUMAN | [view interactions] | Low throughput | no | yes |
BAX_HUMAN | [view interactions] | Low throughput | no | yes |
CASR_HUMAN | [view interactions] | Low throughput | no | no |
KS6B2_HUMAN | [view interactions] | Low throughput | no | yes |
TYK2_HUMAN | [view interactions] | Low throughput | no | no |
PECA1_HUMAN | [view interactions] | Low throughput | no | no |
ATF2_HUMAN | [view interactions] | Low throughput | no | yes |
UD17_HUMAN | [view interactions] | Low throughput | no | no |
TCAM2_HUMAN | [view interactions] | Low throughput | no | no |
KPCE_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCD1_HUMAN | [view interactions] | Low throughput | no | yes |
SYUA_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
FBXW7_HUMAN | [view interactions] | Low throughput | no | yes |
HXK2_HUMAN | [view interactions] | Low throughput | no | yes |
MK01_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAF1_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CFTR_HUMAN | [view interactions] | Low throughput | no | no |
RACK1_HUMAN | [view interactions] | Low throughput | no | yes |
MYH9_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
COPB2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
K2C1_HUMAN | [view interactions] | Low throughput | no | no |
ACTS_HUMAN | [view interactions] | Low throughput | no | no |
PK3CB_HUMAN | [view interactions] | Low throughput | no | yes |
K2C8_HUMAN | [view interactions] | Low throughput | no | no |
K1C18_HUMAN | [view interactions] | Low throughput | no | no |
UBC_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KAT5_HUMAN | [view interactions] | Low throughput | no | yes |
IBTK_HUMAN | [view interactions] | Low throughput | no | yes |
IRAK1_HUMAN | [view interactions] | Low throughput | no | yes |
IKKB_HUMAN | [view interactions] | Low throughput | no | yes |
NEMO_HUMAN | [view interactions] | Low throughput | no | yes |
IL32_HUMAN | [view interactions] | Low throughput | no | no |
ZBT16_HUMAN | [view interactions] | Low throughput | no | yes |
BAD_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
BCL6_HUMAN | [view interactions] | Low throughput | no | no |
TOM20_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PLCG1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAD9A_HUMAN | [view interactions] | Low throughput | no | yes |
KCNC4_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
AFAP1_HUMAN | [view interactions] | Low throughput | no | yes |
PP14A_HUMAN | [view interactions] | Low throughput | no | yes |
GRP3_HUMAN | [view interactions] | Low throughput | no | no |
DCE2_HUMAN | [view interactions] | Low throughput | no | yes |
DCE1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ADAP1_HUMAN | [view interactions] | Low throughput | no | yes |
GNA12_HUMAN | [view interactions] | Low throughput | no | no |
GNA13_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TIAM1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
H11_HUMAN | [view interactions] | Low throughput | no | no |
MARK2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NEUM_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
TAU_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
MARCS_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ITB2_HUMAN | [view interactions] | Low throughput | no | no |
ELAV1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NUMB_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
NANOG_HUMAN | [view interactions] | Low throughput | no | no |
KPCZ_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PDLI5_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
LDB3_HUMAN | [view interactions] | Low throughput | no | no |
LIMK1_HUMAN | [view interactions] | Low throughput | no | yes |
SIN1_HUMAN | [view interactions] | Low throughput | no | yes |
PDPK1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
HS90A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433B_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433Z_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCA_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
KPCI_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VIME_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
ANXA2_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
TRFE_HUMAN | [view interactions] | Low throughput | no | no |
RGAP1_HUMAN | [view interactions] | Low throughput | no | no |
ACTB_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
C1QBP_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
SRC_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
CXA1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
VDAC1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
ADT1_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
G3P_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ENOA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DECR_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
KCRM_HUMAN | [view interactions] | High throughput | no | no |
ATPB_HUMAN | [view interactions] | High throughput | no | yes |
FHL2_HUMAN | [view interactions] | High throughput | no | yes |
MYOZ2_HUMAN | [view interactions] | High throughput | no | no |
CH60_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CSRP3_HUMAN | [view interactions] | High throughput | no | no |
VINC_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
PCD12_HUMAN | [view interactions] | High throughput | no | no |
TNNI3_HUMAN | [view interactions] | High throughput | no | no |
TNNC1_HUMAN | [view interactions] | High throughput | no | no |
TMOD1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYH6_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LMNA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAPZB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CAZA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ACTN2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CYFP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SYGP1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SHAN3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MET_HUMAN | [view interactions] | High throughput | no | yes |
KPYM_HUMAN | [view interactions] | High throughput | no | yes |
A4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M4K4_HUMAN | [view interactions] | High throughput | no | yes |
DESP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
EGFR_HUMAN | [view interactions] | High throughput | no | no |
STAT1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
NMDE2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HNRPL_HUMAN | [view interactions] | High throughput | no | yes |
VIR_HUMAN | [view interactions] | High throughput | no | yes |
TIA1_HUMAN | [view interactions] | High throughput | no | no |
DDX58_HUMAN | [view interactions] | High throughput | no | yes |
BPIA2_HUMAN | [view interactions] | High throughput | no | no |
CYTT_HUMAN | [view interactions] | High throughput | no | no |
CYTS_HUMAN | [view interactions] | High throughput | no | no |
PCBP3_HUMAN | [view interactions] | High throughput | no | yes |
KPCL_HUMAN | [view interactions] | High throughput | no | yes |
T10B_HUMAN | [view interactions] | High throughput | no | yes |
AMY1B_HUMAN | [view interactions] | High throughput | no | no |
AMY1A_HUMAN | [view interactions] | High throughput | no | no |
AMY1C_HUMAN | [view interactions] | High throughput | no | no |
PAPOG_HUMAN | [view interactions] | High throughput | no | yes |
ZG16B_HUMAN | [view interactions] | High throughput | no | no |
SQSTM_HUMAN | [view interactions] | High throughput | no | yes |
ITB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TIAM2_HUMAN | [view interactions] | High throughput | no | yes |
HS90B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PR15A_HUMAN | [view interactions] | High throughput | no | yes |
KPRB_HUMAN | [view interactions] | High throughput | no | yes |
ADT2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB5_HUMAN | [view interactions] | High throughput | no | yes |
HSP7C_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PRPS2_HUMAN | [view interactions] | High throughput | no | no |
ADT3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433T_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PYR1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
DNJA1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PUR9_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433S_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
GDIB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SPB9_HUMAN | [view interactions] | High throughput | no | no |
SPB8_HUMAN | [view interactions] | High throughput | no | no |
SPI2_HUMAN | [view interactions] | High throughput | no | no |
ILEU_HUMAN | [view interactions] | High throughput | no | no |
1433G_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS27A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBA1B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB4B_HUMAN | [view interactions] | High throughput | no | yes |
MPCP_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
DHSO_HUMAN | [view interactions] | High throughput | no | no |
FKBP4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AKA12_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
KEAP1_HUMAN | [view interactions] | High throughput | no | yes |
RCN2_HUMAN | [view interactions] | High throughput | no | yes |
NEDD8_HUMAN | [view interactions] | High throughput | no | yes |
CDC37_HUMAN | [view interactions] | High throughput | no | yes |
FSCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TBB8_HUMAN | [view interactions] | High throughput | no | no |
H90B2_HUMAN | [view interactions] | High throughput | no | no |
TBA1C_HUMAN | [view interactions] | High throughput | no | yes |
NTM1A_HUMAN | [view interactions] | High throughput | no | yes |
BCLF1_HUMAN | [view interactions] | High throughput | no | yes |
TR150_HUMAN | [view interactions] | High throughput | no | yes |
SERC_HUMAN | [view interactions] | High throughput | no | yes |
PAPS1_HUMAN | [view interactions] | High throughput | no | yes |
HSPB1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
G6PD_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
AMPL_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GLYM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECH1_HUMAN | [view interactions] | High throughput | no | yes |
PCKGM_HUMAN | [view interactions] | High throughput | no | no |
DPP2_HUMAN | [view interactions] | High throughput | no | yes |
NOS3_HUMAN | [view interactions] | High throughput | no | no |
AP1B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HMOX1_HUMAN | [view interactions] | High throughput | no | no |
HIF1A_HUMAN | [view interactions] | High throughput | no | no |
MP2K1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PGH2_HUMAN | [view interactions] | High throughput | no | no |
NOS2_HUMAN | [view interactions] | High throughput | no | yes |
MK03_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
P3C2A_HUMAN | [view interactions] | High throughput | no | yes |
MK09_HUMAN | [view interactions] | High throughput | no | yes |
MK08_HUMAN | [view interactions] | High throughput | no | yes |
MAPK2_HUMAN | [view interactions] | High throughput | no | yes |
MK14_HUMAN | [view interactions] | High throughput | no | yes |
AKT1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
BMX_HUMAN | [view interactions] | High throughput | no | no |
LCK_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
MLRV_HUMAN | [view interactions] | High throughput | no | no |
CAV3_HUMAN | [view interactions] | High throughput | no | no |
DESM_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
LAP2A_HUMAN | [view interactions] | High throughput | no | yes |
GOGA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
PHB1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
TPM1_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
FAK2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
CRYAB_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
HS71B_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HS71A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ALDR_HUMAN | [view interactions] | High throughput | no | no |
NMDZ1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IKKA_HUMAN | [view interactions] | High throughput | no | yes |
OGFR_HUMAN | [view interactions] | High throughput | no | yes |
CPVL_HUMAN | [view interactions] | High throughput | no | no |
SRP54_HUMAN | [view interactions] | High throughput | no | yes |
VRK3_HUMAN | [view interactions] | High throughput | no | yes |
ST32A_HUMAN | [view interactions] | High throughput | no | no |
TSSK1_HUMAN | [view interactions] | High throughput | no | no |
ACO13_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
IDH3A_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRPK_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
M2OM_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ATPA_HUMAN | [view interactions] | High throughput | no | yes |
HNRH1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ODPB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MIC19_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
C1QA_HUMAN | [view interactions] | High throughput | no | no |
CRIP2_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
TIAR_HUMAN | [view interactions] | High throughput | no | no |
RS19_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RS18_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
RS3_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
EFTU_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
HNRDL_HUMAN | [view interactions] | High throughput | no | yes |
MYH7_HUMAN | [view interactions] | High throughput | no | no |
ROAA_HUMAN | [view interactions] | High throughput | no | yes |
ROA2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
H4_HUMAN | [view interactions] | High throughput | no | yes |
H13_HUMAN | [view interactions] | High throughput | no | no |
HNRPD_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
ECHA_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NDUA4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SDHB_HUMAN | [view interactions] | High throughput | no | yes |
ECHB_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
JAK3_HUMAN | [view interactions] | Computational | no | no |
IRS2_HUMAN | [view interactions] | Computational | no | yes |
KAPCB_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MOES_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PP1B_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
IL2RA_HUMAN | [view interactions] | Computational | no | no |
2A5D_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PP1G_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KAP2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RASH_HUMAN | [view entry] [view interactions] | Computational | yes | no |
TRPV1_HUMAN | [view entry] [view interactions] | Computational | yes | no |
RRAS_HUMAN | [view interactions] | Computational | no | yes |
MYLK2_HUMAN | [view interactions] | Computational | no | no |
IL2RB_HUMAN | [view interactions] | Computational | no | no |
ADCY3_HUMAN | [view interactions] | Computational | no | yes |
RASN_HUMAN | [view entry] [view interactions] | Computational | yes | no |
BCAR1_HUMAN | [view interactions] | Computational | no | yes |
KPCT_HUMAN | [view interactions] | Computational | no | no |
EZRI_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SHC1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
MYLK3_HUMAN | [view interactions] | Computational | no | no |
PP1A_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY2_HUMAN | [view interactions] | Computational | no | yes |
TRPV4_HUMAN | [view interactions] | Computational | no | yes |
KPCD_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY4_HUMAN | [view interactions] | Computational | no | yes |
CDC42_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
VDAC3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADT4_HUMAN | [view entry] [view interactions] | Computational | yes | no |
CRK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
INSR_HUMAN | [view interactions] | Computational | no | yes |
AKAP9_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PAR3_HUMAN | [view interactions] | Computational | no | no |
ADCY5_HUMAN | [view interactions] | Computational | no | no |
MYLK_HUMAN | [view interactions] | Computational | no | no |
TA2R_HUMAN | [view interactions] | Computational | no | no |
PAK2_HUMAN | [view entry] [view interactions] | Computational | yes | no |
IL2RG_HUMAN | [view interactions] | Computational | no | no |
MYLK4_HUMAN | [view interactions] | Computational | no | no |
TRAF2_HUMAN | [view interactions] | Computational | no | yes |
PPIF_HUMAN | [view interactions] | Computational | no | no |
KAPCG_HUMAN | [view interactions] | Computational | no | no |
VDAC2_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
KAP3_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
AAKG1_HUMAN | [view interactions] | Computational | no | no |
KCNJ8_HUMAN | [view interactions] | Computational | no | yes |
ADCY9_HUMAN | [view interactions] | Computational | no | yes |
SL9A1_HUMAN | [view interactions] | Computational | no | no |
CABIN_HUMAN | [view interactions] | Computational | no | yes |
IL2_HUMAN | [view interactions] | Computational | no | no |
PAK4_HUMAN | [view interactions] | Computational | no | yes |
RASK_HUMAN | [view entry] [view interactions] | Computational | yes | no |
PLPL9_HUMAN | [view interactions] | Computational | no | yes |
RASM_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
PKN1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
SPHK2_HUMAN | [view interactions] | Computational | no | no |
SPHK1_HUMAN | [view interactions] | Computational | no | yes |
TRPA1_HUMAN | [view interactions] | Computational | no | no |
ADCY8_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
ADCY7_HUMAN | [view interactions] | Computational | no | yes |
ADCY6_HUMAN | [view interactions] | Computational | no | yes |
PAR6A_HUMAN | [view interactions] | Computational | no | yes |
IRS1_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
CDK1_HUMAN | [view interactions] | Computational | no | no |
RRAS2_HUMAN | [view interactions] | Computational | no | yes |
JAK1_HUMAN | [view interactions] | Computational | no | yes |
MRP_HUMAN | [view entry] [view interactions] | Computational | yes | no |