Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

DCE1_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB
HPA (protein expression in neurons)

Functions

Catalyzes the production of GABA. [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in DCE1_HUMAN
GO:0043169 cation binding 50.0000 4 no
GO:0046872 metal ion binding 50.0000 5 no
GO:0043168 anion binding 45.4545 4 yes
GO:0000166 nucleotide binding 36.3636 4 no
GO:0017076 purine nucleotide binding 36.3636 5 no
GO:0032555 purine ribonucleotide binding 36.3636 4 no
GO:0035639 purine ribonucleoside triphosphate binding 36.3636 4 no
GO:0005524 ATP binding 31.8182 5 no
GO:0019900 kinase binding 31.8182 4 no
GO:0019901 protein kinase binding 31.8182 5 no
GO:0030554 adenyl nucleotide binding 31.8182 6 no
GO:0032559 adenyl ribonucleotide binding 31.8182 5 no
GO:0016301 kinase activity 27.2727 4 no
GO:0016773 phosphotransferase activity, alcohol group as acceptor 27.2727 4 no
GO:0004351 glutamate decarboxylase activity 9.0909 5 yes
GO:0016831 carboxy-lyase activity 9.0909 4 yes
GO:0030170 pyridoxal phosphate binding 9.0909 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in DCE1_HUMAN
GO:0010646 regulation of cell communication 77.2727 4 no
GO:0048522 positive regulation of cellular process 72.7273 4 no
GO:0009966 regulation of signal transduction 63.6364 4 no
GO:0048523 negative regulation of cellular process 59.0909 4 no
GO:0051049 regulation of transport 59.0909 4 no
GO:1902531 regulation of intracellular signal transduction 59.0909 5 no
GO:0031323 regulation of cellular metabolic process 54.5455 4 no
GO:0009892 negative regulation of metabolic process 50.0000 4 no
GO:0009893 positive regulation of metabolic process 50.0000 4 no
GO:0031325 positive regulation of cellular metabolic process 50.0000 5 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 50.0000 4 no
GO:0080090 regulation of primary metabolic process 50.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 45.4545 5 no
GO:0019220 regulation of phosphate metabolic process 45.4545 6 no
GO:0023056 positive regulation of signaling 45.4545 4 no
GO:0031324 negative regulation of cellular metabolic process 45.4545 5 no
GO:0051050 positive regulation of transport 45.4545 4 no
GO:0051174 regulation of phosphorus metabolic process 45.4545 5 no
GO:0051246 regulation of protein metabolic process 45.4545 5 no
GO:0141124 intracellular signaling cassette 45.4545 4 no
GO:0001932 regulation of protein phosphorylation 40.9091 7 no
GO:0010647 positive regulation of cell communication 40.9091 5 no
GO:0031399 regulation of protein modification process 40.9091 6 no
GO:0034762 regulation of transmembrane transport 40.9091 4 no
GO:0036211 protein modification process 40.9091 4 no
GO:0042325 regulation of phosphorylation 40.9091 7 no
GO:0043412 macromolecule modification 40.9091 4 no
GO:0048584 positive regulation of response to stimulus 40.9091 4 no
GO:0050804 modulation of chemical synaptic transmission 40.9091 5 no
GO:0051726 regulation of cell cycle 40.9091 4 no
GO:0099177 regulation of trans-synaptic signaling 40.9091 4 no
GO:0001934 positive regulation of protein phosphorylation 36.3636 8 no
GO:0010562 positive regulation of phosphorus metabolic process 36.3636 6 no
GO:0010604 positive regulation of macromolecule metabolic process 36.3636 5 no
GO:0010959 regulation of metal ion transport 36.3636 6 no
GO:0031400 negative regulation of protein modification process 36.3636 7 no
GO:0031401 positive regulation of protein modification process 36.3636 7 no
GO:0034765 regulation of monoatomic ion transmembrane transport 36.3636 5 no
GO:0042327 positive regulation of phosphorylation 36.3636 8 no
GO:0043085 positive regulation of catalytic activity 36.3636 4 no
GO:0043269 regulation of monoatomic ion transport 36.3636 5 no
GO:0045937 positive regulation of phosphate metabolic process 36.3636 7 no
GO:0051247 positive regulation of protein metabolic process 36.3636 6 no
GO:0051248 negative regulation of protein metabolic process 36.3636 6 no
GO:0051924 regulation of calcium ion transport 36.3636 7 no
GO:0071310 cellular response to organic substance 36.3636 4 no
GO:1903169 regulation of calcium ion transmembrane transport 36.3636 7 no
GO:1904062 regulation of monoatomic cation transmembrane transport 36.3636 6 no
GO:0006796 phosphate-containing compound metabolic process 31.8182 4 no
GO:0009889 regulation of biosynthetic process 31.8182 4 no
GO:0009967 positive regulation of signal transduction 31.8182 5 no
GO:0009968 negative regulation of signal transduction 31.8182 5 no
GO:0010243 response to organonitrogen compound 31.8182 4 no
GO:0010468 regulation of gene expression 31.8182 6 no
GO:0010556 regulation of macromolecule biosynthetic process 31.8182 5 no
GO:0010563 negative regulation of phosphorus metabolic process 31.8182 6 no
GO:0010648 negative regulation of cell communication 31.8182 5 no
GO:0023057 negative regulation of signaling 31.8182 4 no
GO:0030030 cell projection organization 31.8182 4 no
GO:0031326 regulation of cellular biosynthetic process 31.8182 5 no
GO:0045936 negative regulation of phosphate metabolic process 31.8182 7 no
GO:0048585 negative regulation of response to stimulus 31.8182 4 no
GO:0050776 regulation of immune response 31.8182 4 no
GO:0007268 chemical synaptic transmission 27.2727 7 yes
GO:0098916 anterograde trans-synaptic signaling 27.2727 6 yes
GO:0099536 synaptic signaling 27.2727 4 yes
GO:0099537 trans-synaptic signaling 27.2727 5 yes
GO:0001933 negative regulation of protein phosphorylation 27.2727 8 no
GO:0002684 positive regulation of immune system process 27.2727 4 no
GO:0016310 phosphorylation 27.2727 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 27.2727 5 no
GO:0022607 cellular component assembly 27.2727 4 no
GO:0031344 regulation of cell projection organization 27.2727 5 no
GO:0033674 positive regulation of kinase activity 27.2727 6 no
GO:0042326 negative regulation of phosphorylation 27.2727 8 no
GO:0042981 regulation of apoptotic process 27.2727 5 no
GO:0043067 regulation of programmed cell death 27.2727 4 no
GO:0043549 regulation of kinase activity 27.2727 5 no
GO:0044057 regulation of system process 27.2727 4 no
GO:0045859 regulation of protein kinase activity 27.2727 6 no
GO:0045860 positive regulation of protein kinase activity 27.2727 7 no
GO:0050778 positive regulation of immune response 27.2727 5 no
GO:0050890 cognition 27.2727 4 no
GO:0051130 positive regulation of cellular component organization 27.2727 5 no
GO:0051240 positive regulation of multicellular organismal process 27.2727 4 no
GO:0051279 regulation of release of sequestered calcium ion into cytosol 27.2727 5 no
GO:0051282 regulation of sequestering of calcium ion 27.2727 4 no
GO:0051336 regulation of hydrolase activity 27.2727 4 no
GO:0051338 regulation of transferase activity 27.2727 4 no
GO:0051347 positive regulation of transferase activity 27.2727 5 no
GO:0120035 regulation of plasma membrane bounded cell projection organization 27.2727 6 no
GO:1901701 cellular response to oxygen-containing compound 27.2727 4 no
GO:0032880 regulation of protein localization 27.2727 5 no
GO:0060341 regulation of cellular localization 27.2727 4 no
GO:0070201 regulation of establishment of protein localization 27.2727 6 no
GO:1903829 positive regulation of protein localization 27.2727 5 no
GO:1904951 positive regulation of establishment of protein localization 27.2727 6 no
GO:0010564 regulation of cell cycle process 27.2727 5 no
GO:0051345 positive regulation of hydrolase activity 22.7273 5 no
GO:0071702 organic substance transport 22.7273 4 no
GO:0071705 nitrogen compound transport 22.7273 4 no
GO:0002429 immune response-activating cell surface receptor signaling pathway 22.7273 4 no
GO:0002768 immune response-regulating cell surface receptor signaling pathway 22.7273 4 no
GO:0006355 regulation of DNA-templated transcription 22.7273 7 no
GO:0006468 protein phosphorylation 22.7273 5 no
GO:0006996 organelle organization 22.7273 4 no
GO:0007167 enzyme-linked receptor protein signaling pathway 22.7273 4 no
GO:0008104 protein localization 22.7273 4 no
GO:0009894 regulation of catabolic process 22.7273 4 no
GO:0010975 regulation of neuron projection development 22.7273 7 no
GO:0018193 peptidyl-amino acid modification 22.7273 5 no
GO:0034764 positive regulation of transmembrane transport 22.7273 5 no
GO:0043933 protein-containing complex organization 22.7273 4 no
GO:0044087 regulation of cellular component biogenesis 22.7273 4 no
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 22.7273 5 no
GO:0050807 regulation of synapse organization 22.7273 5 no
GO:0051252 regulation of RNA metabolic process 22.7273 5 no
GO:0071417 cellular response to organonitrogen compound 22.7273 4 no
GO:0071900 regulation of protein serine/threonine kinase activity 22.7273 7 no
GO:0120036 plasma membrane bounded cell projection organization 22.7273 5 no
GO:1901699 cellular response to nitrogen compound 22.7273 4 no
GO:1902532 negative regulation of intracellular signal transduction 22.7273 6 no
GO:1902533 positive regulation of intracellular signal transduction 22.7273 6 no
GO:1903522 regulation of blood circulation 22.7273 5 no
GO:2001141 regulation of RNA biosynthetic process 22.7273 6 no
GO:0055080 monoatomic cation homeostasis 22.7273 4 no
GO:0051046 regulation of secretion 22.7273 5 no
GO:0051047 positive regulation of secretion 22.7273 5 no
GO:1903530 regulation of secretion by cell 22.7273 4 no
GO:1903532 positive regulation of secretion by cell 22.7273 5 no
GO:0009890 negative regulation of biosynthetic process 22.7273 5 no
GO:0010038 response to metal ion 22.7273 4 no
GO:0010558 negative regulation of macromolecule biosynthetic process 22.7273 6 no
GO:0031327 negative regulation of cellular biosynthetic process 22.7273 6 no
GO:0022898 regulation of transmembrane transporter activity 22.7273 4 no
GO:0032412 regulation of monoatomic ion transmembrane transporter activity 22.7273 5 no
GO:0032465 regulation of cytokinesis 22.7273 5 no
GO:0051302 regulation of cell division 22.7273 4 no
GO:1901565 organonitrogen compound catabolic process 18.1818 4 yes
GO:0035641 locomotory exploration behavior 13.6364 4 yes
GO:0043436 oxoacid metabolic process 13.6364 4 yes
GO:0006105 succinate metabolic process 9.0909 7 yes
GO:0006536 glutamate metabolic process 9.0909 6 yes
GO:0006538 glutamate catabolic process 9.0909 7 yes
GO:0006540 glutamate decarboxylation to succinate 9.0909 8 yes
GO:0008652 amino acid biosynthetic process 9.0909 4 yes
GO:0009063 amino acid catabolic process 9.0909 4 yes
GO:0009064 glutamine family amino acid metabolic process 9.0909 5 yes
GO:0009065 glutamine family amino acid catabolic process 9.0909 6 yes
GO:0009448 gamma-aminobutyric acid metabolic process 9.0909 5 yes
GO:0009449 gamma-aminobutyric acid biosynthetic process 9.0909 5 yes
GO:0016053 organic acid biosynthetic process 9.0909 4 yes
GO:0016054 organic acid catabolic process 9.0909 4 yes
GO:0019752 carboxylic acid metabolic process 9.0909 5 yes
GO:0032787 monocarboxylic acid metabolic process 9.0909 6 yes
GO:0043648 dicarboxylic acid metabolic process 9.0909 6 yes
GO:0043649 dicarboxylic acid catabolic process 9.0909 6 yes
GO:0046394 carboxylic acid biosynthetic process 9.0909 5 yes
GO:0046395 carboxylic acid catabolic process 9.0909 5 yes
GO:0170033 L-amino acid metabolic process 9.0909 5 yes
GO:0170035 L-amino acid catabolic process 9.0909 6 yes
GO:0170039 proteinogenic amino acid metabolic process 9.0909 4 yes
GO:0170040 proteinogenic amino acid catabolic process 9.0909 5 yes
GO:0170041 non-proteinogenic amino acid metabolic process 9.0909 4 yes
GO:0170043 non-proteinogenic amino acid biosynthetic process 9.0909 5 yes
GO:1901566 organonitrogen compound biosynthetic process 9.0909 4 yes
GO:1901605 alpha-amino acid metabolic process 9.0909 4 yes
GO:1901606 alpha-amino acid catabolic process 9.0909 5 yes

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
DCE2_HUMAN [view interactions] Low throughput no yes
DCE1_HUMAN [view entry] [view interactions] Low throughput yes yes
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
PRIO_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM2_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM3_HUMAN [view entry] [view interactions] Low throughput yes yes
CALM1_HUMAN [view entry] [view interactions] Low throughput yes yes
BASP1_HUMAN [view entry] [view interactions] Low throughput yes yes
KAPCA_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCE_HUMAN [view entry] [view interactions] Low throughput yes yes
DNMT1_HUMAN [view interactions] Low throughput no no
TET1_HUMAN [view interactions] Low throughput no no
MBD2_HUMAN [view interactions] Low throughput no yes
PP2AB_HUMAN [view interactions] High throughput no yes
RAB3A_HUMAN [view entry] [view interactions] High throughput yes yes
PPP5_HUMAN [view entry] [view interactions] High throughput yes yes
UBP15_HUMAN [view entry] [view interactions] High throughput yes yes
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
FYN_HUMAN [view entry] [view interactions] High throughput yes no
GRB2_HUMAN [view entry] [view interactions] High throughput yes yes
NCK1_HUMAN [view interactions] High throughput no yes
CKLF5_HUMAN [view interactions] High throughput no yes
PSN1_HUMAN [view entry] [view interactions] High throughput yes yes
3HAO_HUMAN [view interactions] High throughput no no
STK3_HUMAN [view interactions] High throughput no yes
ATRAP_HUMAN [view interactions] High throughput no yes
MAL2_HUMAN [view interactions] High throughput no no
JUN_HUMAN [view interactions] High throughput no yes
TRI23_HUMAN [view interactions] High throughput no yes
K1H1_HUMAN [view interactions] High throughput no no
TRIP6_HUMAN [view interactions] High throughput no yes
KRA32_HUMAN [view interactions] High throughput no no
K1C40_HUMAN [view interactions] High throughput no no
FGFR1_HUMAN [view entry] [view interactions] High throughput yes yes
CTRO_HUMAN [view entry] [view interactions] High throughput yes yes
AURKB_HUMAN [view interactions] High throughput no yes
DX39A_HUMAN [view interactions] High throughput no yes
BLK_HUMAN [view interactions] High throughput no no
DCAF6_HUMAN [view interactions] High throughput no no
APLP1_HUMAN [view interactions] High throughput no yes
CALB1_HUMAN [view entry] [view interactions] High throughput yes yes
JMJD6_HUMAN [view interactions] High throughput no yes
VGLU1_HUMAN [view entry] [view interactions] High throughput yes no
SNP25_HUMAN [view entry] [view interactions] High throughput yes yes