Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

FYN_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta-catenin). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT. Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage. Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL1 and TRPC6. Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein. Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation. Phosphorylates PTK2B/PYK2 in response to T-cell receptor activation. Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts. CSK maintains LCK and FYN in an inactive form. Promotes CD28-induced phosphorylation of VAV1. In mast cells, phosphorylates CLNK after activation of immunoglobulin epsilon receptor signaling . [View more on UniProt]

Protein features

Binary interactions with known binding regions

To display all evidence describing the interaction with a partner, click on the protein name left to the bars.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

ELM instance Name Type Start End Partner
ELMI000458 LIG_SH2_SRC LIG 531 534 -
ELMI000129 MOD_TYR_CSK MOD 527 535 -

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in FYN_HUMAN
GO:0017076 purine nucleotide binding 33.4842 4 yes
GO:0032555 purine ribonucleotide binding 33.4842 4 yes
GO:0035639 purine ribonucleoside triphosphate binding 32.1267 4 yes
GO:0019900 kinase binding 29.8643 4 no
GO:0019901 protein kinase binding 28.9593 5 no
GO:0030554 adenyl nucleotide binding 27.6018 5 yes
GO:0032559 adenyl ribonucleotide binding 27.6018 5 yes
GO:0005524 ATP binding 26.2443 5 yes
GO:0046872 metal ion binding 24.4344 4 yes
GO:0016301 kinase activity 17.1946 4 yes
GO:0016773 phosphotransferase activity, alcohol group as acceptor 16.2896 4 yes
GO:0004712 protein serine/threonine/tyrosine kinase activity 15.3846 4 yes
GO:0004713 protein tyrosine kinase activity 9.0498 4 yes
GO:0001664 G protein-coupled receptor binding 8.5973 4 yes
GO:0015631 tubulin binding 7.6923 4 yes
GO:0046875 ephrin receptor binding 5.8824 4 yes
GO:0004715 non-membrane spanning protein tyrosine kinase activity 5.4299 5 yes
GO:0070851 growth factor receptor binding 4.9774 4 yes
GO:0048156 tau protein binding 4.5249 4 yes
GO:0097718 disordered domain specific binding 3.6199 4 yes
GO:0035254 glutamate receptor binding 2.7149 4 yes
GO:0043274 phospholipase binding 2.7149 4 yes
GO:0016004 phospholipase activator activity 1.8100 5 yes
GO:0031802 type 5 metabotropic glutamate receptor binding 1.8100 6 yes
GO:0035256 G protein-coupled glutamate receptor binding 1.8100 5 yes
GO:0043014 alpha-tubulin binding 1.8100 5 yes
GO:0050321 tau-protein kinase activity 1.8100 4 yes
GO:0060229 lipase activator activity 1.8100 4 yes

Biological process

Term Name % Distance from top the of the tree Annotated in FYN_HUMAN
GO:0048522 positive regulation of cellular process 71.0407 4 yes
GO:0048523 negative regulation of cellular process 61.0860 4 yes
GO:0060255 regulation of macromolecule metabolic process 57.9186 4 yes
GO:0080090 regulation of primary metabolic process 55.6561 4 yes
GO:0051128 regulation of cellular component organization 54.2986 4 yes
GO:0051171 regulation of nitrogen compound metabolic process 54.2986 4 yes
GO:0031323 regulation of cellular metabolic process 53.3937 4 yes
GO:0010646 regulation of cell communication 51.5837 4 yes
GO:0009893 positive regulation of metabolic process 48.8688 4 yes
GO:0009966 regulation of signal transduction 47.9638 4 yes
GO:0010604 positive regulation of macromolecule metabolic process 46.6063 5 yes
GO:0051246 regulation of protein metabolic process 44.3439 5 yes
GO:0051173 positive regulation of nitrogen compound metabolic process 42.5339 5 yes
GO:0031325 positive regulation of cellular metabolic process 41.6290 5 yes
GO:0010468 regulation of gene expression 40.7240 5 yes
GO:0022607 cellular component assembly 38.0090 4 no
GO:0009889 regulation of biosynthetic process 35.7466 4 yes
GO:0010941 regulation of cell death 35.2941 4 yes
GO:0048584 positive regulation of response to stimulus 35.2941 4 yes
GO:1902531 regulation of intracellular signal transduction 34.8416 5 yes
GO:0031326 regulation of cellular biosynthetic process 34.8416 5 yes
GO:0051049 regulation of transport 34.3891 4 yes
GO:0031399 regulation of protein modification process 34.3891 6 yes
GO:0010556 regulation of macromolecule biosynthetic process 33.9367 5 no
GO:0051174 regulation of phosphorus metabolic process 33.4842 5 yes
GO:0019220 regulation of phosphate metabolic process 33.4842 6 yes
GO:0051247 positive regulation of protein metabolic process 33.0317 6 yes
GO:0045595 regulation of cell differentiation 32.5792 4 no
GO:0051130 positive regulation of cellular component organization 32.1267 5 yes
GO:0019219 regulation of nucleobase-containing compound metabolic process 32.1267 5 no
GO:0006996 organelle organization 32.1267 4 no
GO:0042981 regulation of apoptotic process 32.1267 6 no
GO:0043067 regulation of programmed cell death 32.1267 5 no
GO:0010647 positive regulation of cell communication 32.1267 5 yes
GO:0023056 positive regulation of signaling 32.1267 4 yes
GO:0030030 cell projection organization 32.1267 4 yes
GO:0009892 negative regulation of metabolic process 31.6742 4 yes
GO:0043085 positive regulation of catalytic activity 31.6742 4 yes
GO:0010605 negative regulation of macromolecule metabolic process 30.7692 5 yes
GO:0042325 regulation of phosphorylation 30.7692 7 yes
GO:0071310 cellular response to organic substance 29.4118 4 yes
GO:0009967 positive regulation of signal transduction 28.9593 5 yes
GO:0051172 negative regulation of nitrogen compound metabolic process 28.5068 5 yes
GO:0006796 phosphate-containing compound metabolic process 28.5068 4 yes
GO:0120036 plasma membrane bounded cell projection organization 28.0543 5 yes
GO:0008104 protein localization 28.0543 4 no
GO:0033043 regulation of organelle organization 28.0543 5 no
GO:0022603 regulation of anatomical structure morphogenesis 28.0543 4 yes
GO:0001932 regulation of protein phosphorylation 27.6018 7 yes
GO:0051094 positive regulation of developmental process 27.6018 4 no
GO:0060341 regulation of cellular localization 27.1493 4 yes
GO:0031344 regulation of cell projection organization 27.1493 5 yes
GO:0120035 regulation of plasma membrane bounded cell projection organization 26.6968 6 yes
GO:0031324 negative regulation of cellular metabolic process 26.6968 5 yes
GO:0036211 protein modification process 26.6968 4 yes
GO:0043412 macromolecule modification 26.6968 4 yes
GO:0051240 positive regulation of multicellular organismal process 25.7919 4 no
GO:0010562 positive regulation of phosphorus metabolic process 25.7919 6 yes
GO:0045937 positive regulation of phosphate metabolic process 25.7919 7 yes
GO:0051336 regulation of hydrolase activity 25.3394 4 yes
GO:0060548 negative regulation of cell death 25.3394 5 yes
GO:0051252 regulation of RNA metabolic process 25.3394 5 no
GO:0042127 regulation of cell population proliferation 25.3394 4 no
GO:0032880 regulation of protein localization 25.3394 5 yes
GO:0043933 protein-containing complex organization 24.8869 4 no
GO:0044087 regulation of cellular component biogenesis 24.8869 4 no
GO:0030155 regulation of cell adhesion 24.8869 4 yes
GO:0031401 positive regulation of protein modification process 24.8869 7 yes
GO:0048585 negative regulation of response to stimulus 24.8869 4 yes
GO:0006355 regulation of DNA-templated transcription 24.4344 6 no
GO:0051338 regulation of transferase activity 24.4344 4 no
GO:1903506 regulation of nucleic acid-templated transcription 24.4344 7 no
GO:2001141 regulation of RNA biosynthetic process 24.4344 6 no
GO:0042327 positive regulation of phosphorylation 24.4344 8 yes
GO:0051129 negative regulation of cellular component organization 23.9819 5 yes
GO:0010648 negative regulation of cell communication 23.9819 5 no
GO:0023057 negative regulation of signaling 23.9819 4 no
GO:2000145 regulation of cell motility 23.9819 4 no
GO:2000026 regulation of multicellular organismal development 23.5294 4 no
GO:0043066 negative regulation of apoptotic process 23.0769 7 no
GO:0043069 negative regulation of programmed cell death 23.0769 6 no
GO:0080134 regulation of response to stress 22.6244 4 yes
GO:0065003 protein-containing complex assembly 22.6244 5 no
GO:0030334 regulation of cell migration 22.6244 5 no
GO:0009891 positive regulation of biosynthetic process 22.6244 5 no
GO:0051248 negative regulation of protein metabolic process 22.1719 6 yes
GO:1902533 positive regulation of intracellular signal transduction 22.1719 6 yes
GO:0031328 positive regulation of cellular biosynthetic process 22.1719 6 no
GO:0045935 positive regulation of nucleobase-containing compound metabolic process 22.1719 6 no
GO:0007167 enzyme-linked receptor protein signaling pathway 22.1719 4 yes
GO:0009968 negative regulation of signal transduction 21.7195 5 no
GO:0045597 positive regulation of cell differentiation 21.7195 5 no
GO:0001934 positive regulation of protein phosphorylation 21.2670 8 yes
GO:0043549 regulation of kinase activity 20.8145 5 no
GO:0010557 positive regulation of macromolecule biosynthetic process 20.8145 6 no
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 20.8145 5 yes
GO:0010975 regulation of neuron projection development 20.8145 7 yes
GO:0051050 positive regulation of transport 20.3620 4 yes
GO:0007010 cytoskeleton organization 20.3620 5 no
GO:0010243 response to organonitrogen compound 20.3620 4 yes
GO:1901701 cellular response to oxygen-containing compound 19.9095 4 yes
GO:0031175 neuron projection development 19.4570 6 yes
GO:0016310 phosphorylation 19.0045 5 yes
GO:0099177 regulation of trans-synaptic signaling 18.5520 4 yes
GO:0030162 regulation of proteolysis 18.5520 6 yes
GO:0050804 modulation of chemical synaptic transmission 18.5520 5 yes
GO:0050776 regulation of immune response 18.0995 4 yes
GO:0002684 positive regulation of immune system process 17.6471 4 yes
GO:0009894 regulation of catabolic process 17.1946 4 yes
GO:0051345 positive regulation of hydrolase activity 16.7421 5 yes
GO:1903829 positive regulation of protein localization 16.7421 5 yes
GO:0006468 protein phosphorylation 16.7421 5 yes
GO:0070201 regulation of establishment of protein localization 16.2896 6 yes
GO:0031346 positive regulation of cell projection organization 16.2896 6 yes
GO:1901214 regulation of neuron death 15.8371 5 yes
GO:0022604 regulation of cell morphogenesis 15.8371 5 yes
GO:0043269 regulation of ion transport 15.8371 5 yes
GO:0031400 negative regulation of protein modification process 15.3846 7 yes
GO:0032101 regulation of response to external stimulus 15.3846 4 yes
GO:0045785 positive regulation of cell adhesion 15.3846 5 yes
GO:0010942 positive regulation of cell death 14.9321 5 yes
GO:0034762 regulation of transmembrane transport 14.9321 4 yes
GO:0050865 regulation of cell activation 14.4796 4 yes
GO:0071417 cellular response to organonitrogen compound 14.0271 4 yes
GO:0080135 regulation of cellular response to stress 14.0271 4 yes
GO:1901699 cellular response to nitrogen compound 14.0271 4 yes
GO:0002694 regulation of leukocyte activation 13.5747 4 yes
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 13.5747 8 yes
GO:0120039 plasma membrane bounded cell projection morphogenesis 13.1222 6 yes
GO:0009890 negative regulation of biosynthetic process 13.1222 5 yes
GO:0032990 cell part morphogenesis 13.1222 4 yes
GO:0048812 neuron projection morphogenesis 13.1222 7 yes
GO:0048858 cell projection morphogenesis 13.1222 5 yes
GO:1904951 positive regulation of establishment of protein localization 12.6697 6 yes
GO:0045862 positive regulation of proteolysis 12.6697 7 yes
GO:0051223 regulation of protein transport 12.2172 5 yes
GO:0051249 regulation of lymphocyte activation 12.2172 5 yes
GO:0018193 peptidyl-amino acid modification 12.2172 5 yes
GO:0031327 negative regulation of cellular biosynthetic process 12.2172 6 yes
GO:0034765 regulation of ion transmembrane transport 12.2172 5 yes
GO:0052547 regulation of peptidase activity 11.7647 5 yes
GO:0052548 regulation of endopeptidase activity 11.7647 6 yes
GO:0022407 regulation of cell-cell adhesion 11.7647 5 yes
GO:0032386 regulation of intracellular transport 11.7647 5 yes
GO:0070848 response to growth factor 11.3122 4 yes
GO:0010629 negative regulation of gene expression 11.3122 6 yes
GO:0050807 regulation of synapse organization 11.3122 5 yes
GO:0050863 regulation of T cell activation 11.3122 6 yes
GO:0071363 cellular response to growth factor stimulus 10.8597 5 yes
GO:0010959 regulation of metal ion transport 10.4072 6 yes
GO:0031345 negative regulation of cell projection organization 10.4072 6 yes
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 10.4072 9 yes
GO:0050778 positive regulation of immune response 10.4072 5 yes
GO:1900180 regulation of protein localization to nucleus 9.9548 6 yes
GO:1904062 regulation of cation transmembrane transport 9.9548 6 yes
GO:0002768 immune response-regulating cell surface receptor signaling pathway 9.9548 4 yes
GO:0097485 neuron projection guidance 9.5023 7 yes
GO:1901652 response to peptide 9.5023 4 yes
GO:2000116 regulation of cysteine-type endopeptidase activity 9.5023 7 yes
GO:0007411 axon guidance 9.5023 8 yes
GO:0031347 regulation of defense response 9.5023 5 yes
GO:0046777 protein autophosphorylation 9.5023 6 yes
GO:0050890 cognition 9.5023 4 yes
GO:0051222 positive regulation of protein transport 9.0498 5 yes
GO:1903037 regulation of leukocyte cell-cell adhesion 9.0498 6 yes
GO:0002429 immune response-activating cell surface receptor signaling pathway 9.0498 4 yes
GO:0042176 regulation of protein catabolic process 9.0498 5 yes
GO:0050867 positive regulation of cell activation 9.0498 5 yes
GO:0051924 regulation of calcium ion transport 8.5973 7 yes
GO:1900182 positive regulation of protein localization to nucleus 8.5973 6 yes
GO:1905475 regulation of protein localization to membrane 8.5973 6 yes
GO:0002696 positive regulation of leukocyte activation 8.5973 5 yes
GO:0006811 ion transport 8.5973 4 yes
GO:0032388 positive regulation of intracellular transport 8.5973 5 yes
GO:0033157 regulation of intracellular protein transport 8.5973 6 yes
GO:0051251 positive regulation of lymphocyte activation 8.1448 6 yes
GO:0097305 response to alcohol 8.1448 4 yes
GO:0099175 regulation of postsynapse organization 8.1448 6 yes
GO:0008360 regulation of cell shape 8.1448 6 yes
GO:0010950 positive regulation of endopeptidase activity 8.1448 7 yes
GO:0010952 positive regulation of peptidase activity 8.1448 6 yes
GO:0032103 positive regulation of response to external stimulus 8.1448 5 yes
GO:0090316 positive regulation of intracellular protein transport 7.6923 6 yes
GO:0002683 negative regulation of immune system process 7.6923 4 yes
GO:1901653 cellular response to peptide 7.2398 5 yes
GO:1903039 positive regulation of leukocyte cell-cell adhesion 7.2398 7 yes
GO:2000377 regulation of reactive oxygen species metabolic process 7.2398 5 yes
GO:0002831 regulation of response to biotic stimulus 7.2398 4 yes
GO:0006812 cation transport 7.2398 5 yes
GO:0010976 positive regulation of neuron projection development 7.2398 7 yes
GO:0022409 positive regulation of cell-cell adhesion 7.2398 6 yes
GO:0048013 ephrin receptor signaling pathway 7.2398 6 yes
GO:0050870 positive regulation of T cell activation 7.2398 7 yes
GO:1901216 positive regulation of neuron death 6.7873 6 yes
GO:1903169 regulation of calcium ion transmembrane transport 6.7873 7 yes
GO:1903320 regulation of protein modification by small protein conjugation or removal 6.7873 7 yes
GO:0009895 negative regulation of catabolic process 6.7873 5 yes
GO:0018108 peptidyl-tyrosine phosphorylation 6.7873 6 yes
GO:0018212 peptidyl-tyrosine modification 6.7873 6 yes
GO:2001056 positive regulation of cysteine-type endopeptidase activity 6.3348 8 yes
GO:0001764 neuron migration 6.3348 4 yes
GO:0030001 metal ion transport 6.3348 6 yes
GO:0032102 negative regulation of response to external stimulus 6.3348 5 yes
GO:0099173 postsynapse organization 5.8824 4 yes
GO:0106027 neuron projection organization 5.8824 6 yes
GO:0007612 learning 5.8824 4 yes
GO:0031396 regulation of protein ubiquitination 5.8824 8 yes
GO:0038093 Fc receptor signaling pathway 5.8824 5 yes
GO:0045088 regulation of innate immune response 5.8824 5 yes
GO:0050851 antigen receptor-mediated signaling pathway 5.8824 5 yes
GO:1905477 positive regulation of protein localization to membrane 5.4299 6 yes
GO:0000302 response to reactive oxygen species 5.4299 4 yes
GO:0097061 dendritic spine organization 4.9774 5 yes
GO:0050852 T cell receptor signaling pathway 4.9774 6 yes
GO:0002431 Fc receptor mediated stimulatory signaling pathway 4.5249 5 yes
GO:0031348 negative regulation of defense response 4.5249 5 yes
GO:0031349 positive regulation of defense response 4.5249 5 yes
GO:0038094 Fc-gamma receptor signaling pathway 4.5249 6 yes
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 4.5249 4 yes
GO:0042177 negative regulation of protein catabolic process 4.5249 6 yes
GO:0050727 regulation of inflammatory response 4.5249 5 yes
GO:1903321 negative regulation of protein modification by small protein conjugation or removal 4.0724 8 yes
GO:1904645 response to amyloid-beta 4.0724 5 yes
GO:0042110 T cell activation 4.0724 4 yes
GO:0042542 response to hydrogen peroxide 4.0724 4 yes
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 4.0724 6 yes
GO:0045471 response to ethanol 4.0724 5 yes
GO:0048813 dendrite morphogenesis 4.0724 8 yes
GO:0050777 negative regulation of immune response 4.0724 5 yes
GO:0071560 cellular response to transforming growth factor beta stimulus 3.6199 4 yes
GO:1904646 cellular response to amyloid-beta 3.6199 6 yes
GO:0002833 positive regulation of response to biotic stimulus 3.6199 5 yes
GO:0006816 calcium ion transport 3.6199 7 yes
GO:0031397 negative regulation of protein ubiquitination 3.6199 9 yes
GO:0048010 vascular endothelial growth factor receptor signaling pathway 3.6199 6 yes
GO:1903533 regulation of protein targeting 3.1674 7 yes
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 3.1674 9 yes
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 3.1674 7 yes
GO:0043200 response to amino acid 3.1674 4 yes
GO:0045089 positive regulation of innate immune response 3.1674 6 yes
GO:0050728 negative regulation of inflammatory response 3.1674 6 yes
GO:0090313 regulation of protein targeting to membrane 2.7149 7 yes
GO:0090314 positive regulation of protein targeting to membrane 2.7149 7 yes
GO:1900407 regulation of cellular response to oxidative stress 2.7149 5 yes
GO:1902882 regulation of response to oxidative stress 2.7149 5 yes
GO:1903201 regulation of oxidative stress-induced cell death 2.7149 5 yes
GO:1990858 cellular response to lectin 2.7149 4 yes
GO:0002220 innate immune response activating cell surface receptor signaling pathway 2.7149 5 yes
GO:0002223 stimulatory C-type lectin receptor signaling pathway 2.7149 5 yes
GO:0002758 innate immune response-activating signal transduction 2.7149 4 yes
GO:0002861 regulation of inflammatory response to antigenic stimulus 2.7149 5 yes
GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2.7149 6 yes
GO:0010310 regulation of hydrogen peroxide metabolic process 2.7149 6 yes
GO:0032943 mononuclear cell proliferation 2.7149 4 yes
GO:0043954 cellular component maintenance 2.7149 4 yes
GO:0046651 lymphocyte proliferation 2.7149 4 yes
GO:0050982 detection of mechanical stimulus 2.2624 4 yes
GO:0097062 dendritic spine maintenance 2.2624 5 yes
GO:1902950 regulation of dendritic spine maintenance 2.2624 7 yes
GO:1902951 negative regulation of dendritic spine maintenance 2.2624 7 yes
GO:1903426 regulation of reactive oxygen species biosynthetic process 2.2624 5 yes
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2.2624 10 yes
GO:0071229 cellular response to acid chemical 1.8100 4 yes
GO:1900449 regulation of glutamate receptor signaling pathway 1.8100 5 yes
GO:1903202 negative regulation of oxidative stress-induced cell death 1.8100 6 yes
GO:2000378 negative regulation of reactive oxygen species metabolic process 1.8100 6 yes
GO:0036120 cellular response to platelet-derived growth factor stimulus 1.8100 4 yes
GO:0042098 T cell proliferation 1.8100 5 yes
GO:0062149 detection of stimulus involved in sensory perception of pain 1.3575 4 yes
GO:0071230 cellular response to amino acid stimulus 1.3575 5 yes
GO:1903427 negative regulation of reactive oxygen species biosynthetic process 1.3575 6 yes
GO:1905429 response to glycine 1.3575 5 yes
GO:1905664 regulation of calcium ion import across plasma membrane 1.3575 8 yes
GO:0003015 heart process 1.3575 4 yes
GO:0050798 activated T cell proliferation 1.3575 6 yes
GO:1902065 response to L-glutamate 0.9050 5 yes
GO:1905232 cellular response to L-glutamate 0.9050 6 yes
GO:1905430 cellular response to glycine 0.9050 6 yes
GO:0000304 response to singlet oxygen 0.9050 4 yes
GO:0010727 negative regulation of hydrogen peroxide metabolic process 0.9050 7 yes
GO:0010728 regulation of hydrogen peroxide biosynthetic process 0.9050 6 yes
GO:0010730 negative regulation of hydrogen peroxide biosynthetic process 0.9050 7 yes
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain 0.9050 5 yes
GO:0050974 detection of mechanical stimulus involved in sensory perception 0.9050 4 yes

Disease

Term Name % Distance from top the of the tree Annotated in FYN_HUMAN
DOID:331 central nervous system disease 4.5249 3 no
DOID:936 brain disease 2.2624 4 no
DOID:1289 neurodegenerative disease 2.2624 4 no
DOID:612 primary immunodeficiency disease 1.8100 3 no
DOID:0050686 organ system cancer 1.8100 3 no
DOID:0050155 sensory system disease 1.3575 3 no
DOID:0050753 cerebellar ataxia 1.3575 6 no
DOID:0050951 hereditary ataxia 1.3575 5 no
DOID:0050701 electroclinical syndrome 1.3575 6 no
DOID:0112202 developmental and epileptic encephalopathy 1.3575 7 no
DOID:1826 epilepsy 1.3575 5 no
DOID:114 heart disease 1.3575 3 no
DOID:0050563 nonsyndromic deafness 0.9050 5 no
DOID:0060038 specific developmental disorder 0.9050 3 no
DOID:1059 intellectual disability 0.9050 4 no
DOID:2742 auditory system disease 0.9050 4 no
DOID:0050950 autosomal recessive cerebellar ataxia 0.9050 7 no
DOID:1441 autosomal dominant cerebellar ataxia 0.9050 7 no
DOID:3490 Noonan syndrome 0.9050 3 no
DOID:0080001 bone disease 0.9050 4 no
DOID:0080006 bone development disease 0.9050 5 no
DOID:65 connective tissue disease 0.9050 3 no
DOID:0111962 combined immunodeficiency 0.9050 4 no
DOID:193 reproductive organ cancer 0.9050 4 no
DOID:0080000 muscular disease 0.9050 3 no
DOID:423 myopathy 0.9050 5 no
DOID:66 muscle tissue disease 0.9050 4 no
DOID:9884 muscular dystrophy 0.9050 6 no
DOID:231 motor neuron disease 0.9050 5 no
DOID:332 amyotrophic lateral sclerosis 0.9050 6 no
DOID:0050700 cardiomyopathy 0.9050 4 no
DOID:0060036 intrinsic cardiomyopathy 0.9050 5 no
DOID:1247 blood coagulation disease 0.9050 3 no
DOID:2218 blood platelet disease 0.9050 4 no

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
PTPRF_HUMAN [view entry] [view interactions] Low throughput yes yes
DAG1_HUMAN [view entry] [view interactions] Low throughput yes no
3BP2_HUMAN [view interactions] Low throughput no yes
FYB1_HUMAN [view interactions] Low throughput no no
VAV2_HUMAN [view entry] [view interactions] Low throughput yes yes
VAV_HUMAN [view interactions] Low throughput no no
SOS1_HUMAN [view entry] [view interactions] Low throughput yes yes
ERBB4_HUMAN [view entry] [view interactions] Low throughput yes yes
PTPRZ_HUMAN [view entry] [view interactions] Low throughput yes yes
MED28_HUMAN [view interactions] Low throughput no yes
PHAG1_HUMAN [view interactions] Low throughput no yes
FZD2_HUMAN [view interactions] Low throughput no no
TRPC6_HUMAN [view interactions] Low throughput no no
U119A_HUMAN [view interactions] Low throughput no no
KHDR1_HUMAN [view interactions] Low throughput no yes
NMDE1_HUMAN [view entry] [view interactions] Low throughput yes yes
NPHN_HUMAN [view interactions] Low throughput no no
CTND1_HUMAN [view entry] [view interactions] Low throughput yes no
FAK1_HUMAN [view entry] [view interactions] Low throughput yes yes
CADH1_HUMAN [view entry] [view interactions] Low throughput yes no
YES_HUMAN [view entry] [view interactions] Low throughput yes yes
ACHA7_HUMAN [view entry] [view interactions] Low throughput yes yes
5HT6R_HUMAN [view interactions] Low throughput no yes
JAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
RHG33_HUMAN [view interactions] Low throughput no yes
DLG4_HUMAN [view entry] [view interactions] Low throughput yes yes
RHG32_HUMAN [view entry] [view interactions] Low throughput yes yes
CBLC_HUMAN [view interactions] Low throughput no yes
KPCT_HUMAN [view interactions] Low throughput no no
ZAP70_HUMAN [view interactions] Low throughput no no
CD36_HUMAN [view interactions] Low throughput no no
CDK1_HUMAN [view interactions] Low throughput no no
RAF1_HUMAN [view entry] [view interactions] Low throughput yes no
PDC6I_HUMAN [view entry] [view interactions] Low throughput yes yes
TBA3C_HUMAN [view interactions] Low throughput no no
TBA3D_HUMAN [view interactions] Low throughput no no
NTRK2_HUMAN [view entry] [view interactions] Low throughput yes yes
MUC18_HUMAN [view interactions] Low throughput no yes
SLAF1_HUMAN [view interactions] Low throughput no no
PECA1_HUMAN [view interactions] Low throughput no no
G3BP1_HUMAN [view interactions] Low throughput no yes
CD20_HUMAN [view interactions] Low throughput no no
VGFR2_HUMAN [view interactions] Low throughput no no
CASL_HUMAN [view interactions] Low throughput no yes
PTPRE_HUMAN [view interactions] Low throughput no no
RACK1_HUMAN [view interactions] Low throughput no yes
PTPRA_HUMAN [view interactions] Low throughput no yes
IL7RA_HUMAN [view interactions] Low throughput no no
PTN11_HUMAN [view entry] [view interactions] Low throughput yes yes
PLXA2_HUMAN [view entry] [view interactions] Low throughput yes yes
CD44_HUMAN [view interactions] Low throughput no yes
CDK5_HUMAN [view entry] [view interactions] Low throughput yes yes
PAXI_HUMAN [view interactions] Low throughput no yes
GRM1_HUMAN [view entry] [view interactions] Low throughput yes yes
PTN5_HUMAN [view entry] [view interactions] Low throughput yes yes
TRPV4_HUMAN [view interactions] Low throughput no yes
EPHA4_HUMAN [view entry] [view interactions] Low throughput yes yes
TYK2_HUMAN [view interactions] Low throughput no no
KSYK_HUMAN [view interactions] Low throughput no no
SIT1_HUMAN [view interactions] Low throughput no no
THY1_HUMAN [view entry] [view interactions] Low throughput yes yes
ACK1_HUMAN [view interactions] Low throughput no yes
CD226_HUMAN [view interactions] Low throughput no yes
ITCH_HUMAN [view interactions] Low throughput no yes
NFIP2_HUMAN [view interactions] Low throughput no yes
SH21A_HUMAN [view interactions] Low throughput no no
UBC_HUMAN [view entry] [view interactions] Low throughput yes yes
FRK_HUMAN [view interactions] Low throughput no no
FGFR2_HUMAN [view interactions] Low throughput no yes
CD5_HUMAN [view interactions] Low throughput no no
TM1L1_HUMAN [view interactions] Low throughput no yes
KCNA2_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNA4_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNA5_HUMAN [view interactions] Low throughput no no
DIAP1_HUMAN [view interactions] Low throughput no yes
CD244_HUMAN [view interactions] Low throughput no no
SRC_HUMAN [view entry] [view interactions] Low throughput yes no
ZN106_HUMAN [view interactions] Low throughput no no
PDE4D_HUMAN [view entry] [view interactions] Low throughput yes yes
NEMO_HUMAN [view interactions] Low throughput no yes
IFM3_HUMAN [view interactions] Low throughput no yes
GBB1_HUMAN [view entry] [view interactions] Low throughput yes yes
GBG2_HUMAN [view entry] [view interactions] Low throughput yes yes
KS6A3_HUMAN [view entry] [view interactions] Low throughput yes yes
KALRN_HUMAN [view entry] [view interactions] Low throughput yes yes
SDC1_HUMAN [view interactions] Low throughput no no
SOCS1_HUMAN [view interactions] Low throughput no yes
DOK2_HUMAN [view interactions] Low throughput no no
KIT_HUMAN [view interactions] Low throughput no no
CBL_HUMAN [view interactions] Low throughput no yes
PGFRB_HUMAN [view interactions] Low throughput no yes
SKAP1_HUMAN [view interactions] Low throughput no no
CTLA4_HUMAN [view interactions] Low throughput no no
FAK2_HUMAN [view entry] [view interactions] Low throughput yes yes
HNRPK_HUMAN [view entry] [view interactions] Low throughput yes yes
KCNA3_HUMAN [view entry] [view interactions] Low throughput yes no
SHC1_HUMAN [view entry] [view interactions] Low throughput yes yes
WASP_HUMAN [view interactions] Low throughput no yes
CTNB1_HUMAN [view entry] [view interactions] Low throughput yes yes
CD2_HUMAN [view interactions] Low throughput no no
SKAP2_HUMAN [view interactions] Low throughput no no
BCL3_HUMAN [view interactions] Low throughput no yes
PLCG2_HUMAN [view interactions] Low throughput no yes
P85A_HUMAN [view interactions] Low throughput no yes
CBLB_HUMAN [view interactions] Low throughput no yes
TNFL6_HUMAN [view interactions] Low throughput no yes
ADA15_HUMAN [view interactions] Low throughput no yes
GPVI_HUMAN [view interactions] Low throughput no no
LCP2_HUMAN [view interactions] Low throughput no yes
CLIC5_HUMAN [view interactions] Low throughput no no
ADDB_HUMAN [view entry] [view interactions] Low throughput yes yes
CSK_HUMAN [view interactions] Low throughput no yes
CSF1R_HUMAN [view interactions] Low throughput no yes
IRS1_HUMAN [view entry] [view interactions] Low throughput yes yes
CENPV_HUMAN [view interactions] Low throughput no yes
TAU_HUMAN [view entry] [view interactions] Low throughput yes yes
WASL_HUMAN [view entry] [view interactions] Low throughput yes yes
DCBD2_HUMAN [view interactions] Low throughput no yes
STAT3_HUMAN [view entry] [view interactions] Low throughput yes yes
HAVR2_HUMAN [view interactions] Low throughput no no
PLCG1_HUMAN [view entry] [view interactions] Low throughput yes yes
KPCD_HUMAN [view entry] [view interactions] Low throughput yes yes
LAT_HUMAN [view interactions] Low throughput no no
MTA1_HUMAN [view interactions] Low throughput no yes
ERBB2_HUMAN [view entry] [view interactions] Low throughput yes no
MTA3_HUMAN [view interactions] Low throughput no yes
CLNK_HUMAN [view interactions] Low throughput no no
P85B_HUMAN [view interactions] Low throughput no yes
HCLS1_HUMAN [view interactions] Low throughput no no
GAB3_HUMAN [view interactions] Low throughput no yes
SPHK1_HUMAN [view interactions] Low throughput no yes
BTK_HUMAN [view interactions] Low throughput no no
SPHK2_HUMAN [view interactions] Low throughput no no
NCK1_HUMAN [view interactions] Low throughput no yes
EPHB3_HUMAN [view interactions] Low throughput no yes
ITK_HUMAN [view interactions] Low throughput no no
EPHA8_HUMAN [view interactions] Low throughput no no
RL10_HUMAN [view entry] [view interactions] Low throughput yes yes
NCOA2_HUMAN [view interactions] Low throughput no no
SDC3_HUMAN [view interactions] Low throughput no yes
SLAF7_HUMAN [view interactions] Low throughput no no
NMDE2_HUMAN [view entry] [view interactions] Low throughput yes no
TMM47_HUMAN [view interactions] Low throughput no no
MAG_HUMAN [view entry] [view interactions] Low throughput yes yes
CDCP1_HUMAN [view interactions] Low throughput no yes
EPHA3_HUMAN [view interactions] Low throughput no yes
VGFR1_HUMAN [view interactions] Low throughput no no
TRAF6_HUMAN [view interactions] Low throughput no yes
MTAP2_HUMAN [view entry] [view interactions] Low throughput yes yes
ENAH_HUMAN [view entry] [view interactions] Low throughput yes yes
FYN_HUMAN [view entry] [view interactions] Low throughput yes no
FMN1_HUMAN [view interactions] Low throughput no no
TNFA_HUMAN [view interactions] Low throughput no no
IL1B_HUMAN [view interactions] Low throughput no no
PTPRC_HUMAN [view interactions] Low throughput no no
EFS_HUMAN [view interactions] Low throughput no no
LCK_HUMAN [view entry] [view interactions] Low throughput yes no
ANM8_HUMAN [view interactions] Low throughput no yes
GRB10_HUMAN [view entry] [view interactions] Low throughput yes yes
NMT1_HUMAN [view interactions] Low throughput no yes
ENOA_HUMAN [view entry] [view interactions] Low throughput yes yes
CLH1_HUMAN [view entry] [view interactions] Low throughput yes yes
NMDZ1_HUMAN [view entry] [view interactions] Low throughput yes yes
GRASP_HUMAN [view entry] [view interactions] Low throughput yes yes
STXB1_HUMAN [view entry] [view interactions] Low throughput yes yes
ASAP1_HUMAN [view entry] [view interactions] Low throughput yes yes
DAB1_HUMAN [view interactions] Low throughput no yes
CMA1_HUMAN [view interactions] Low throughput no no
TNR1A_HUMAN [view interactions] Low throughput no yes
SYUA_HUMAN [view entry] [view interactions] Low throughput yes no
CAV1_HUMAN [view interactions] Low throughput no no
TNR6_HUMAN [view interactions] Low throughput no no
DLG2_HUMAN [view entry] [view interactions] Low throughput yes yes
BCAR1_HUMAN [view interactions] Low throughput no yes
RRAS_HUMAN [view interactions] High throughput no yes
DEN2A_HUMAN [view interactions] High throughput no no
SPN90_HUMAN [view entry] [view interactions] High throughput yes no
LSM3_HUMAN [view interactions] High throughput no yes
FANCA_HUMAN [view interactions] High throughput no no
ZN615_HUMAN [view interactions] High throughput no no
CKAP5_HUMAN [view entry] [view interactions] High throughput yes yes
CSEN_HUMAN [view interactions] High throughput no no
HDAC6_HUMAN [view interactions] High throughput no yes
JAK1_HUMAN [view interactions] High throughput no yes
SNX3_HUMAN [view entry] [view interactions] High throughput yes no
A16L1_HUMAN [view entry] [view interactions] High throughput yes yes
BRPF3_HUMAN [view interactions] High throughput no yes
AAPK1_HUMAN [view interactions] High throughput no no
IL3RA_HUMAN [view interactions] High throughput no yes
DHAS1_HUMAN [view interactions] High throughput no no
XRCC1_HUMAN [view entry] [view interactions] High throughput yes yes
PAK5_HUMAN [view interactions] High throughput no yes
LTBP2_HUMAN [view interactions] High throughput no no
NYAP2_HUMAN [view interactions] High throughput no no
M4K5_HUMAN [view interactions] High throughput no no
DAB2_HUMAN [view interactions] High throughput no yes
SDCB1_HUMAN [view entry] [view interactions] High throughput yes yes
HCN4_HUMAN [view interactions] High throughput no yes
SH3G2_HUMAN [view entry] [view interactions] High throughput yes yes
STF1_HUMAN [view interactions] High throughput no no
SH3G3_HUMAN [view entry] [view interactions] High throughput yes no
DOCK1_HUMAN [view entry] [view interactions] High throughput yes yes
RU17_HUMAN [view interactions] High throughput no yes
GPR63_HUMAN [view interactions] High throughput no yes
STK4_HUMAN [view interactions] High throughput no yes
HEXA_HUMAN [view interactions] High throughput no yes
ZN419_HUMAN [view interactions] High throughput no yes
I20L2_HUMAN [view interactions] High throughput no yes
MEG10_HUMAN [view interactions] High throughput no no
TULP4_HUMAN [view interactions] High throughput no yes
DNJA3_HUMAN [view entry] [view interactions] High throughput yes yes
BRCA2_HUMAN [view interactions] High throughput no no
JIP1_HUMAN [view entry] [view interactions] High throughput yes yes
TDRD1_HUMAN [view interactions] High throughput no no
PPCEL_HUMAN [view interactions] High throughput no yes
DYN3_HUMAN [view entry] [view interactions] High throughput yes no
NUAK1_HUMAN [view interactions] High throughput no no
NCKP5_HUMAN [view interactions] High throughput no no
SV2A_HUMAN [view entry] [view interactions] High throughput yes yes
UHRF2_HUMAN [view interactions] High throughput no no
SUV92_HUMAN [view interactions] High throughput no no
ABI1_HUMAN [view entry] [view interactions] High throughput yes yes
FCG2B_HUMAN [view interactions] High throughput no no
TRI63_HUMAN [view interactions] High throughput no no
FCG2C_HUMAN [view interactions] High throughput no no
TRI55_HUMAN [view interactions] High throughput no no
NEK8_HUMAN [view interactions] High throughput no yes
BET1_HUMAN [view interactions] High throughput no no
CELR3_HUMAN [view interactions] High throughput no no
GASR_HUMAN [view interactions] High throughput no no
EXTL3_HUMAN [view interactions] High throughput no yes
RP1L1_HUMAN [view interactions] High throughput no no
MEOX2_HUMAN [view interactions] High throughput no no
MOS_HUMAN [view interactions] High throughput no no
ERRFI_HUMAN [view interactions] High throughput no no
SNX17_HUMAN [view interactions] High throughput no yes
BAG4_HUMAN [view interactions] High throughput no yes
F90A1_HUMAN [view interactions] High throughput no no
DTX3_HUMAN [view interactions] High throughput no yes
GRSF1_HUMAN [view interactions] High throughput no yes
ADA12_HUMAN [view interactions] High throughput no no
TMG4_HUMAN [view interactions] High throughput no yes
RAVR1_HUMAN [view interactions] High throughput no yes
DYLT1_HUMAN [view interactions] High throughput no no
UCK2_HUMAN [view interactions] High throughput no no
ATX1_HUMAN [view interactions] High throughput no yes
CG025_HUMAN [view interactions] High throughput no yes
CH033_HUMAN [view interactions] High throughput no yes
TNNT1_HUMAN [view interactions] High throughput no no
SUV91_HUMAN [view interactions] High throughput no no
KDM1A_HUMAN [view interactions] High throughput no yes
ANM6_HUMAN [view interactions] High throughput no yes
HS90B_HUMAN [view entry] [view interactions] High throughput yes yes
MYH9_HUMAN [view entry] [view interactions] High throughput yes no
ANLN_HUMAN [view interactions] High throughput no yes
MY18A_HUMAN [view entry] [view interactions] High throughput yes yes
FLNB_HUMAN [view interactions] High throughput no no
COR1C_HUMAN [view entry] [view interactions] High throughput yes yes
ZNFX1_HUMAN [view interactions] High throughput no yes
MARE1_HUMAN [view entry] [view interactions] High throughput yes yes
OSGEP_HUMAN [view interactions] High throughput no yes
SODC_HUMAN [view interactions] High throughput no yes
PMS2_HUMAN [view interactions] High throughput no yes
GCR_HUMAN [view entry] [view interactions] High throughput yes yes
OCRL_HUMAN [view interactions] High throughput no yes
CD3G_HUMAN [view interactions] High throughput no no
RUXG_HUMAN [view interactions] High throughput no yes
KPRB_HUMAN [view interactions] High throughput no yes
SH3K1_HUMAN [view entry] [view interactions] High throughput yes yes
FETUA_HUMAN [view interactions] High throughput no no
NPM_HUMAN [view entry] [view interactions] High throughput yes yes
HS90A_HUMAN [view entry] [view interactions] High throughput yes yes
ROA1_HUMAN [view entry] [view interactions] High throughput yes yes
RA1L2_HUMAN [view interactions] High throughput no no
H14_HUMAN [view interactions] High throughput no yes
BIP_HUMAN [view entry] [view interactions] High throughput yes yes
HSP7C_HUMAN [view entry] [view interactions] High throughput yes yes
PRPS2_HUMAN [view interactions] High throughput no no
EF2_HUMAN [view entry] [view interactions] High throughput yes yes
TRI27_HUMAN [view interactions] High throughput no yes
DESP_HUMAN [view entry] [view interactions] High throughput yes no
HMGA1_HUMAN [view interactions] High throughput no yes
CCDC8_HUMAN [view interactions] High throughput no yes
FBRL_HUMAN [view interactions] High throughput no yes
ABCE1_HUMAN [view interactions] High throughput no yes
KAPCB_HUMAN [view entry] [view interactions] High throughput yes yes
S2541_HUMAN [view interactions] High throughput no no
SYVC_HUMAN [view interactions] High throughput no yes
HXB5_HUMAN [view interactions] High throughput no no
METK2_HUMAN [view interactions] High throughput no no
M2OM_HUMAN [view entry] [view interactions] High throughput yes yes
HSP74_HUMAN [view entry] [view interactions] High throughput yes yes
ANR12_HUMAN [view interactions] High throughput no yes
KIF11_HUMAN [view interactions] High throughput no yes
T185A_HUMAN [view interactions] High throughput no no
IF5_HUMAN [view interactions] High throughput no yes
CCNL2_HUMAN [view interactions] High throughput no yes
PRPS1_HUMAN [view entry] [view interactions] High throughput yes no
SMD2_HUMAN [view interactions] High throughput no yes
TIF1B_HUMAN [view interactions] High throughput no yes
LIMK1_HUMAN [view interactions] High throughput no yes
KPRA_HUMAN [view interactions] High throughput no no
TSNAX_HUMAN [view interactions] High throughput no yes
LBR_HUMAN [view interactions] High throughput no yes
T132A_HUMAN [view interactions] High throughput no yes
CDC37_HUMAN [view interactions] High throughput no yes
KS6A1_HUMAN [view interactions] High throughput no yes
MEPCE_HUMAN [view interactions] High throughput no yes
PAIRB_HUMAN [view interactions] High throughput no yes
KS6A2_HUMAN [view interactions] High throughput no yes
HS105_HUMAN [view entry] [view interactions] High throughput yes yes
KPCI_HUMAN [view entry] [view interactions] High throughput yes yes
UBP7_HUMAN [view interactions] High throughput no yes
MED21_HUMAN [view interactions] High throughput no yes
NADAP_HUMAN [view interactions] High throughput no yes
LRIQ1_HUMAN [view interactions] High throughput no no
NS1BP_HUMAN [view interactions] High throughput no yes
PCDGK_HUMAN [view interactions] High throughput no yes
PRP8_HUMAN [view interactions] High throughput no yes
PTPRD_HUMAN [view entry] [view interactions] High throughput yes no
SNR40_HUMAN [view interactions] High throughput no yes
ACBD7_HUMAN [view interactions] High throughput no no
DDX23_HUMAN [view interactions] High throughput no yes
CXB7_HUMAN [view interactions] High throughput no no
RT12_HUMAN [view interactions] High throughput no yes
MTUS2_HUMAN [view interactions] High throughput no yes
SNUT1_HUMAN [view interactions] High throughput no yes
TR10B_HUMAN [view interactions] High throughput no no
U520_HUMAN [view interactions] High throughput no yes
S4A8_HUMAN [view interactions] High throughput no no
PRP6_HUMAN [view interactions] High throughput no yes
ARNT_HUMAN [view entry] [view interactions] High throughput yes yes
CD2B2_HUMAN [view interactions] High throughput no yes
HAVR1_HUMAN [view interactions] High throughput no yes
ENPL_HUMAN [view entry] [view interactions] High throughput yes yes
HEXI1_HUMAN [view interactions] High throughput no yes
ITA3_HUMAN [view entry] [view interactions] High throughput yes yes
LARP7_HUMAN [view interactions] High throughput no yes
PTBP1_HUMAN [view interactions] High throughput no no
PYR1_HUMAN [view entry] [view interactions] High throughput yes yes
PRDX2_HUMAN [view entry] [view interactions] High throughput yes yes
ILF3_HUMAN [view interactions] High throughput no yes
ROA0_HUMAN [view interactions] High throughput no yes
DX39B_HUMAN [view interactions] High throughput no no
CD3Z_HUMAN [view interactions] High throughput no no
U5S1_HUMAN [view interactions] High throughput no yes
CD3D_HUMAN [view interactions] High throughput no no
CCAR2_HUMAN [view interactions] High throughput no yes
PKHA4_HUMAN [view interactions] High throughput no yes
RP9_HUMAN [view interactions] High throughput no yes
HS71B_HUMAN [view entry] [view interactions] High throughput yes yes
TECR_HUMAN [view interactions] High throughput no yes
HS71A_HUMAN [view entry] [view interactions] High throughput yes yes
TMA7_HUMAN [view interactions] High throughput no no
EMC1_HUMAN [view interactions] High throughput no yes
ZBT18_HUMAN [view interactions] High throughput no yes
CHM4B_HUMAN [view entry] [view interactions] High throughput yes yes
ECT2_HUMAN [view interactions] High throughput no no
KIF14_HUMAN [view interactions] High throughput no no
KI20A_HUMAN [view interactions] High throughput no yes
KIF23_HUMAN [view interactions] High throughput no yes
NPC1_HUMAN [view interactions] High throughput no yes
SRCN1_HUMAN [view entry] [view interactions] High throughput yes yes
MKRN2_HUMAN [view interactions] High throughput no yes
CX001_HUMAN [view interactions] High throughput no no
MALL_HUMAN [view interactions] High throughput no no
CERS2_HUMAN [view interactions] High throughput no no
RN149_HUMAN [view interactions] High throughput no no
TEX19_HUMAN [view interactions] High throughput no no
CPNE9_HUMAN [view interactions] High throughput no no
VATC2_HUMAN [view interactions] High throughput no yes
CTNA3_HUMAN [view interactions] High throughput no no
HXA9_HUMAN [view interactions] High throughput no yes
SP20H_HUMAN [view interactions] High throughput no yes
CB39L_HUMAN [view interactions] High throughput no yes
TRI39_HUMAN [view interactions] High throughput no no
STRN3_HUMAN [view interactions] High throughput no yes
MAAI_HUMAN [view interactions] High throughput no yes
KCNC3_HUMAN [view entry] [view interactions] High throughput yes yes
PRIC3_HUMAN [view interactions] High throughput no yes
CA226_HUMAN [view interactions] High throughput no yes
ORC1_HUMAN [view interactions] High throughput no yes
SSX3_HUMAN [view interactions] High throughput no no
DOCK3_HUMAN [view entry] [view interactions] High throughput yes yes
DHC24_HUMAN [view interactions] High throughput no yes
CENPA_HUMAN [view interactions] High throughput no no
TRM6_HUMAN [view interactions] High throughput no yes
AKAP6_HUMAN [view interactions] High throughput no no
MAK16_HUMAN [view interactions] High throughput no yes
TRAIP_HUMAN [view interactions] High throughput no yes
APC16_HUMAN [view interactions] High throughput no yes
LRBA_HUMAN [view interactions] High throughput no yes
SMAD2_HUMAN [view interactions] High throughput no yes
M4K1_HUMAN [view interactions] High throughput no no
KAP0_HUMAN [view entry] [view interactions] High throughput yes yes
RPP38_HUMAN [view interactions] High throughput no yes
F135B_HUMAN [view interactions] High throughput no no
HCN2_HUMAN [view entry] [view interactions] High throughput yes no
KHDR2_HUMAN [view interactions] High throughput no yes
FACC1_HUMAN [view interactions] High throughput no no
DLX4_HUMAN [view interactions] High throughput no no
DDR1_HUMAN [view interactions] High throughput no yes
GID8_HUMAN [view interactions] High throughput no yes
RPGF1_HUMAN [view interactions] High throughput no yes
ADA10_HUMAN [view entry] [view interactions] High throughput yes yes
SSH1_HUMAN [view interactions] High throughput no yes
GNS_HUMAN [view interactions] High throughput no yes
EHD4_HUMAN [view entry] [view interactions] High throughput yes no
ACVR1_HUMAN [view interactions] High throughput no yes
ASB16_HUMAN [view interactions] High throughput no no
PGM1_HUMAN [view interactions] High throughput no no
TM204_HUMAN [view interactions] High throughput no yes
ASAP2_HUMAN [view interactions] High throughput no yes
PRP4B_HUMAN [view interactions] High throughput no yes
RPC10_HUMAN [view interactions] High throughput no yes
DUS15_HUMAN [view interactions] High throughput no no
ABITM_HUMAN [view interactions] High throughput no yes
SREC2_HUMAN [view interactions] High throughput no yes
SEC20_HUMAN [view interactions] High throughput no yes
MND1_HUMAN [view interactions] High throughput no no
GPR45_HUMAN [view interactions] High throughput no no
RAPH1_HUMAN [view entry] [view interactions] High throughput yes yes
RNF31_HUMAN [view interactions] High throughput no yes
SOS2_HUMAN [view interactions] High throughput no yes
RPR1B_HUMAN [view interactions] High throughput no yes
SIAH1_HUMAN [view interactions] High throughput no yes
PDIA2_HUMAN [view interactions] High throughput no no
APBA3_HUMAN [view interactions] High throughput no yes
EST2_HUMAN [view interactions] High throughput no yes
NBEA_HUMAN [view entry] [view interactions] High throughput yes yes
FUS_HUMAN [view entry] [view interactions] High throughput yes yes
COPG1_HUMAN [view interactions] High throughput no yes
SYNJ2_HUMAN [view entry] [view interactions] High throughput yes yes
AMPB_HUMAN [view interactions] High throughput no yes
P66A_HUMAN [view interactions] High throughput no yes
MEPE_HUMAN [view interactions] High throughput no no
SC23B_HUMAN [view interactions] High throughput no yes
ASCL4_HUMAN [view interactions] High throughput no no
DCE1_HUMAN [view entry] [view interactions] High throughput yes yes
LKHA4_HUMAN [view interactions] High throughput no yes
AMHR2_HUMAN [view interactions] High throughput no no
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
STXB2_HUMAN [view interactions] High throughput no no
FGOP2_HUMAN [view interactions] High throughput no yes
CSMD2_HUMAN [view interactions] High throughput no no
SF3B1_HUMAN [view interactions] High throughput no yes
MRAP2_HUMAN [view interactions] High throughput no no
RIN3_HUMAN [view interactions] High throughput no yes
GRB7_HUMAN [view interactions] High throughput no no
MAGE1_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP2_HUMAN [view entry] [view interactions] High throughput yes no
NUMB_HUMAN [view entry] [view interactions] High throughput yes yes
SRS10_HUMAN [view interactions] High throughput no yes
PAR3_HUMAN [view interactions] High throughput no no
G6PD_HUMAN [view entry] [view interactions] High throughput yes no
TMTC4_HUMAN [view interactions] High throughput no yes
DLGP4_HUMAN [view entry] [view interactions] High throughput yes yes
MRCKB_HUMAN [view entry] [view interactions] High throughput yes yes
BIRC8_HUMAN [view interactions] High throughput no no
GABR1_HUMAN [view entry] [view interactions] High throughput yes yes
PARVA_HUMAN [view interactions] High throughput no yes
CLD20_HUMAN [view interactions] High throughput no no
TGON2_HUMAN [view interactions] High throughput no yes
IPO7_HUMAN [view entry] [view interactions] High throughput yes yes
HAUS7_HUMAN [view interactions] High throughput no no
EPS15_HUMAN [view entry] [view interactions] High throughput yes yes
FETUB_HUMAN [view interactions] High throughput no no
CB073_HUMAN [view interactions] High throughput no no
HNRPR_HUMAN [view interactions] High throughput no yes
PPT1_HUMAN [view interactions] High throughput no yes
AT5F1_HUMAN [view interactions] High throughput no yes
SELN_HUMAN [view interactions] High throughput no yes
TCPH_HUMAN [view entry] [view interactions] High throughput yes yes
CATL1_HUMAN [view interactions] High throughput no yes
NPVF_HUMAN [view interactions] High throughput no no
H90B4_HUMAN [view interactions] High throughput no no
IFM1_HUMAN [view interactions] High throughput no no
CD2AP_HUMAN [view interactions] High throughput no no
TCPB_HUMAN [view entry] [view interactions] High throughput yes yes
CLC4E_HUMAN [view interactions] High throughput no no
KMT2B_HUMAN [view interactions] High throughput no no
TCPD_HUMAN [view entry] [view interactions] High throughput yes yes
TM192_HUMAN [view interactions] High throughput no yes
APOL5_HUMAN [view interactions] High throughput no no
TCPQ_HUMAN [view entry] [view interactions] High throughput yes yes
RHOU_HUMAN [view interactions] High throughput no no
TF3A_HUMAN [view interactions] High throughput no yes
TCPG_HUMAN [view entry] [view interactions] High throughput yes yes
RHOH_HUMAN [view interactions] High throughput no yes
NKX21_HUMAN [view interactions] High throughput no no
TCPE_HUMAN [view entry] [view interactions] High throughput yes yes
RHOA_HUMAN [view entry] [view interactions] High throughput yes yes
DLGP3_HUMAN [view entry] [view interactions] High throughput yes yes
TCPZ_HUMAN [view entry] [view interactions] High throughput yes yes
CDC42_HUMAN [view entry] [view interactions] High throughput yes yes
SHAN3_HUMAN [view entry] [view interactions] High throughput yes no
TCPA_HUMAN [view entry] [view interactions] High throughput yes yes
RAC1_HUMAN [view entry] [view interactions] High throughput yes no
ARHGB_HUMAN [view interactions] High throughput no yes
AIP_HUMAN [view entry] [view interactions] High throughput yes yes
RAC2_HUMAN [view entry] [view interactions] High throughput yes yes
F110A_HUMAN [view interactions] High throughput no yes
PIM3_HUMAN [view interactions] High throughput no no
RHOB_HUMAN [view entry] [view interactions] High throughput yes no
PAX3_HUMAN [view interactions] High throughput no no
HASP_HUMAN [view interactions] High throughput no yes
RHOC_HUMAN [view interactions] High throughput no no
FLNC_HUMAN [view entry] [view interactions] High throughput yes no
RHOF_HUMAN [view interactions] High throughput no no
NCKX1_HUMAN [view interactions] High throughput no no
PAK2_HUMAN [view entry] [view interactions] High throughput yes no
RND2_HUMAN [view interactions] High throughput no no
SP1_HUMAN [view interactions] High throughput no yes
RIMS2_HUMAN [view entry] [view interactions] High throughput yes no
CNTFR_HUMAN [view entry] [view interactions] High throughput yes yes
TULP1_HUMAN [view interactions] High throughput no no
DNSL2_HUMAN [view interactions] High throughput no no
CNTP1_HUMAN [view entry] [view interactions] High throughput yes yes
TRAT1_HUMAN [view interactions] High throughput no no
ABL1_HUMAN [view entry] [view interactions] High throughput yes yes
SNX12_HUMAN [view entry] [view interactions] High throughput yes yes
PTPRT_HUMAN [view entry] [view interactions] High throughput yes yes
ABL2_HUMAN [view entry] [view interactions] High throughput yes yes
HXC8_HUMAN [view interactions] High throughput no no
PAX7_HUMAN [view interactions] High throughput no no
WNK2_HUMAN [view interactions] High throughput no yes
GUC2D_HUMAN [view interactions] High throughput no no
RTN4_HUMAN [view entry] [view interactions] High throughput yes yes
NEDD4_HUMAN [view entry] [view interactions] High throughput yes yes
NFS1_HUMAN [view interactions] High throughput no yes
MET_HUMAN [view interactions] High throughput no yes
NELFB_HUMAN [view interactions] High throughput no no
SF3B4_HUMAN [view interactions] High throughput no yes
NFASC_HUMAN [view entry] [view interactions] High throughput yes yes
TELT_HUMAN [view interactions] High throughput no no
CO6_HUMAN [view interactions] High throughput no yes
CAPON_HUMAN [view entry] [view interactions] High throughput yes yes
CP4F2_HUMAN [view interactions] High throughput no no
P55G_HUMAN [view interactions] High throughput no yes
GCFC2_HUMAN [view interactions] High throughput no no
PPR3D_HUMAN [view interactions] High throughput no yes
WBP11_HUMAN [view interactions] High throughput no yes
RASH_HUMAN [view entry] [view interactions] High throughput yes no
PKD1_HUMAN [view interactions] High throughput no yes
AKT1_HUMAN [view entry] [view interactions] High throughput yes yes
BAZ2A_HUMAN [view interactions] High throughput no no
CCKN_HUMAN [view interactions] High throughput no yes
AIRE_HUMAN [view interactions] High throughput no no
CBS_HUMAN [view interactions] High throughput no yes
KS6B2_HUMAN [view interactions] High throughput no yes
KI67_HUMAN [view interactions] High throughput no no
G3P_HUMAN [view entry] [view interactions] High throughput yes yes
CCR10_HUMAN [view interactions] High throughput no yes
CBX1_HUMAN [view interactions] High throughput no yes
DDX41_HUMAN [view interactions] High throughput no yes
PNPH_HUMAN [view interactions] High throughput no no
DPOD1_HUMAN [view interactions] High throughput no yes
HMOX2_HUMAN [view entry] [view interactions] High throughput yes yes
FLNA_HUMAN [view entry] [view interactions] High throughput yes no
RAN_HUMAN [view entry] [view interactions] High throughput yes no
DKKL1_HUMAN [view interactions] High throughput no no
CHIP_HUMAN [view entry] [view interactions] High throughput yes yes
APH1A_HUMAN [view interactions] High throughput no yes
CDC27_HUMAN [view interactions] High throughput no yes
CYC_HUMAN [view entry] [view interactions] High throughput yes yes
MBP_HUMAN [view entry] [view interactions] High throughput yes no
SNX8_HUMAN [view interactions] High throughput no yes
PEN2_HUMAN [view interactions] High throughput no yes
DLGP1_HUMAN [view entry] [view interactions] High throughput yes no
A4_HUMAN [view entry] [view interactions] High throughput yes yes
TSKS_HUMAN [view interactions] High throughput no no
FOXF2_HUMAN [view interactions] High throughput no no
TRI69_HUMAN [view interactions] High throughput no no
ELOV5_HUMAN [view interactions] High throughput no yes
MED14_HUMAN [view interactions] High throughput no no
FLT3_HUMAN [view interactions] High throughput no no
ERGI1_HUMAN [view interactions] High throughput no yes
BMP8B_HUMAN [view interactions] High throughput no no
PANX1_HUMAN [view interactions] High throughput no no
WIPF1_HUMAN [view interactions] High throughput no no
ACE2_HUMAN [view interactions] High throughput no no
MLP3B_HUMAN [view interactions] High throughput no yes
E41L3_HUMAN [view entry] [view interactions] High throughput yes yes
PDIA6_HUMAN [view entry] [view interactions] High throughput yes yes
TAXB1_HUMAN [view interactions] High throughput no yes
PRAX_HUMAN [view interactions] High throughput no no
ARL4C_HUMAN [view interactions] High throughput no yes
MYPT1_HUMAN [view entry] [view interactions] High throughput yes yes
CSN6_HUMAN [view interactions] High throughput no yes
ARAP2_HUMAN [view interactions] High throughput no no
CAF1A_HUMAN [view interactions] High throughput no yes
UHMK1_HUMAN [view interactions] High throughput no no
SEM7A_HUMAN [view interactions] High throughput no yes
PRUN2_HUMAN [view entry] [view interactions] High throughput yes yes
PTN4_HUMAN [view interactions] High throughput no no
EPHA5_HUMAN [view interactions] High throughput no no
SHRM2_HUMAN [view interactions] High throughput no yes
ADX_HUMAN [view interactions] High throughput no no
ICAL_HUMAN [view interactions] High throughput no yes
NYAP1_HUMAN [view interactions] High throughput no no
CDKL5_HUMAN [view entry] [view interactions] High throughput yes yes
MYO16_HUMAN [view interactions] High throughput no no
VP13A_HUMAN [view interactions] High throughput no yes
EPHA1_HUMAN [view interactions] High throughput no yes
CAC1F_HUMAN [view interactions] High throughput no no
ATRN1_HUMAN [view interactions] High throughput no no
LYN_HUMAN [view entry] [view interactions] Computational yes no
CASR_HUMAN [view interactions] Computational no no
UNC5B_HUMAN [view interactions] Computational no yes
ITB5_HUMAN [view interactions] Computational no yes
ITA2B_HUMAN [view interactions] Computational no no
S1PR1_HUMAN [view interactions] Computational no no
MK14_HUMAN [view interactions] Computational no yes
FCERG_HUMAN [view interactions] Computational no no
PODO_HUMAN [view interactions] Computational no no
EFNA1_HUMAN [view interactions] Computational no no
2A5E_HUMAN [view interactions] Computational no yes
ACTN1_HUMAN [view entry] [view interactions] Computational yes yes
BLNK_HUMAN [view entry] [view interactions] Computational yes no
SEM3A_HUMAN [view interactions] Computational no no
ARHG7_HUMAN [view entry] [view interactions] Computational yes yes
PP2AA_HUMAN [view entry] [view interactions] Computational yes yes
2A5G_HUMAN [view interactions] Computational no yes
EFNA3_HUMAN [view interactions] Computational no yes
MK01_HUMAN [view entry] [view interactions] Computational yes yes
2AAA_HUMAN [view entry] [view interactions] Computational yes no
GPC1_HUMAN [view entry] [view interactions] Computational yes no
VINC_HUMAN [view entry] [view interactions] Computational yes no
GNAI2_HUMAN [view entry] [view interactions] Computational yes yes
BMX_HUMAN [view interactions] Computational no no
SHC2_HUMAN [view interactions] Computational no yes
PI3R6_HUMAN [view interactions] Computational no yes
LRP8_HUMAN [view entry] [view interactions] Computational yes no
STA5B_HUMAN [view interactions] Computational no yes
NTAL_HUMAN [view interactions] Computational no no
PTN6_HUMAN [view interactions] Computational no no
EPHA7_HUMAN [view entry] [view interactions] Computational yes no
PLXA1_HUMAN [view entry] [view interactions] Computational yes yes
ROBO1_HUMAN [view interactions] Computational no yes
ITAV_HUMAN [view interactions] Computational no yes
NCK2_HUMAN [view entry] [view interactions] Computational yes yes
GRB2_HUMAN [view entry] [view interactions] Computational yes yes
CLC6A_HUMAN [view interactions] Computational no no
JAK3_HUMAN [view interactions] Computational no no
PK3CG_HUMAN [view interactions] Computational no yes
PTN21_HUMAN [view interactions] Computational no yes
GRAA_HUMAN [view interactions] Computational no no
DAPP1_HUMAN [view interactions] Computational no yes
TIE2_HUMAN [view interactions] Computational no no
EGF_HUMAN [view interactions] Computational no no
RAC3_HUMAN [view entry] [view interactions] Computational yes no
SLAP1_HUMAN [view interactions] Computational no yes
MK08_HUMAN [view interactions] Computational no yes
2A5B_HUMAN [view interactions] Computational no yes
PRIO_HUMAN [view entry] [view interactions] Computational yes yes
PP2AB_HUMAN [view interactions] Computational no yes
M3K11_HUMAN [view interactions] Computational no yes
DOK1_HUMAN [view interactions] Computational no yes
ELMO1_HUMAN [view interactions] Computational no no
TYOBP_HUMAN [view interactions] Computational no no
2AAB_HUMAN [view interactions] Computational no yes
SHC3_HUMAN [view interactions] Computational no yes
2A5D_HUMAN [view entry] [view interactions] Computational yes yes
EGFR_HUMAN [view interactions] Computational no no
CTNA1_HUMAN [view entry] [view interactions] Computational yes yes
PDGFB_HUMAN [view interactions] Computational no yes
TDGF1_HUMAN [view interactions] Computational no no
GAB2_HUMAN [view interactions] Computational no yes
MP2K7_HUMAN [view entry] [view interactions] Computational yes yes
IL2RB_HUMAN [view interactions] Computational no no
EFNB1_HUMAN [view interactions] Computational no yes
STAT1_HUMAN [view entry] [view interactions] Computational yes no
UNC5C_HUMAN [view interactions] Computational no no
PLD2_HUMAN [view interactions] Computational no yes
EPHB2_HUMAN [view entry] [view interactions] Computational yes yes
ARRB2_HUMAN [view entry] [view interactions] Computational yes no
GSK3B_HUMAN [view entry] [view interactions] Computational yes yes
PK3CD_HUMAN [view interactions] Computational no no
STA5A_HUMAN [view interactions] Computational no no
RASK_HUMAN [view entry] [view interactions] Computational yes no
CD3E_HUMAN [view interactions] Computational no no
KIRR1_HUMAN [view interactions] Computational no no
DCC_HUMAN [view entry] [view interactions] Computational yes yes
MK11_HUMAN [view interactions] Computational no yes
SHC4_HUMAN [view entry] [view interactions] Computational yes no
IL2_HUMAN [view interactions] Computational no no
GIT2_HUMAN [view interactions] Computational no yes
DRA_HUMAN [view interactions] Computational no no
FINC_HUMAN [view interactions] Computational no yes
EFNA2_HUMAN [view interactions] Computational no no
PC11X_HUMAN [view interactions] Computational no yes
FCERB_HUMAN [view interactions] Computational no no
HLAA_HUMAN [view interactions] Computational no no
SH3G1_HUMAN [view entry] [view interactions] Computational yes no
FCG2A_HUMAN [view interactions] Computational no no
CD79A_HUMAN [view interactions] Computational no no
NCHL1_HUMAN [view entry] [view interactions] Computational yes yes
RASA1_HUMAN [view interactions] Computational no yes
FCGR1_HUMAN [view interactions] Computational no no
EPHB1_HUMAN [view interactions] Computational no no
CADH5_HUMAN [view interactions] Computational no yes
CD4_HUMAN [view interactions] Computational no no
VLDLR_HUMAN [view interactions] Computational no yes
NRG1_HUMAN [view entry] [view interactions] Computational yes no
NET1_HUMAN [view interactions] Computational no no
CD8B_HUMAN [view interactions] Computational no no
CAV2_HUMAN [view interactions] Computational no no
SRC8_HUMAN [view entry] [view interactions] Computational yes yes
PLXA3_HUMAN [view entry] [view interactions] Computational yes no
PLAK_HUMAN [view entry] [view interactions] Computational yes yes
CAN2_HUMAN [view interactions] Computational no no
CRK_HUMAN [view entry] [view interactions] Computational yes no
ANGP2_HUMAN [view interactions] Computational no no
ARHG2_HUMAN [view entry] [view interactions] Computational yes yes
CD8A_HUMAN [view interactions] Computational no no
DRB1_HUMAN [view interactions] Computational no no
MK12_HUMAN [view interactions] Computational no no
ITA1_HUMAN [view interactions] Computational no yes
NRP1_HUMAN [view entry] [view interactions] Computational yes yes
ML12A_HUMAN [view interactions] Computational no no
CD79B_HUMAN [view interactions] Computational no no
IL2RG_HUMAN [view interactions] Computational no no
PI3R5_HUMAN [view interactions] Computational no no
2A5A_HUMAN [view interactions] Computational no yes
AFAD_HUMAN [view interactions] Computational no yes
NRCAM_HUMAN [view entry] [view interactions] Computational yes no
ITB1_HUMAN [view entry] [view interactions] Computational yes no
FGR_HUMAN [view interactions] Computational no no
PAK1_HUMAN [view entry] [view interactions] Computational yes yes
NGEF_HUMAN [view entry] [view interactions] Computational yes yes
KAPCG_HUMAN [view interactions] Computational no no
EFNA5_HUMAN [view interactions] Computational no yes
PK3CA_HUMAN [view entry] [view interactions] Computational yes yes
EFNA4_HUMAN [view interactions] Computational no no
TRAF2_HUMAN [view interactions] Computational no yes
SH21B_HUMAN [view interactions] Computational no no
RELN_HUMAN [view interactions] Computational no no
CH60_HUMAN [view entry] [view interactions] Computational yes yes
KAPCA_HUMAN [view entry] [view interactions] Computational yes yes
TRPV6_HUMAN [view interactions] Computational no no
PTN13_HUMAN [view interactions] Computational no yes
EPHA2_HUMAN [view interactions] Computational no no
MK13_HUMAN [view interactions] Computational no yes
CD28_HUMAN [view interactions] Computational no no
BLK_HUMAN [view interactions] Computational no no
CRKL_HUMAN [view entry] [view interactions] Computational yes yes
FCERA_HUMAN [view interactions] Computational no yes
RASN_HUMAN [view entry] [view interactions] Computational yes no
PK3CB_HUMAN [view interactions] Computational no yes
PLXA4_HUMAN [view entry] [view interactions] Computational yes no
CAV3_HUMAN [view interactions] Computational no no
RHG35_HUMAN [view interactions] Computational no yes
JIP3_HUMAN [view entry] [view interactions] Computational yes yes