RIMS2_HUMAN
Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (PubMed). [View more on UniProt]
To display all evidence describing the interaction with a partner, click on the protein name left to the bars.
No data found.
No annotated instance was found. To search for linear motifs, use the ELM prediction server.
Molecular function
Term | Name | % | Distance from the top of the tree | Annotated in RIMS2_HUMAN |
---|---|---|---|---|
GO:0017076 | purine nucleotide binding | 33.3333 | 4 | no |
GO:0032555 | purine ribonucleotide binding | 33.3333 | 4 | no |
GO:0046872 | metal ion binding | 28.5714 | 4 | yes |
GO:0035639 | purine ribonucleoside triphosphate binding | 28.5714 | 4 | no |
GO:0031267 | small GTPase binding | 23.8095 | 5 | yes |
GO:0051020 | GTPase binding | 23.8095 | 4 | yes |
GO:0019900 | kinase binding | 23.8095 | 4 | no |
GO:0019901 | protein kinase binding | 23.8095 | 5 | no |
Biological process
Term | Name | % | Distance from top the of the tree | Annotated in RIMS2_HUMAN |
---|---|---|---|---|
GO:0051049 | regulation of transport | 76.1905 | 4 | yes |
GO:0016192 | vesicle-mediated transport | 66.6667 | 4 | yes |
GO:0048522 | positive regulation of cellular process | 66.6667 | 4 | yes |
GO:0008104 | protein localization | 57.1429 | 4 | yes |
GO:0010646 | regulation of cell communication | 57.1429 | 4 | yes |
GO:0071702 | organic substance transport | 57.1429 | 4 | yes |
GO:0071705 | nitrogen compound transport | 57.1429 | 4 | yes |
GO:0015031 | protein transport | 52.3810 | 4 | yes |
GO:0046903 | secretion | 52.3810 | 4 | yes |
GO:0051128 | regulation of cellular component organization | 52.3810 | 4 | yes |
GO:0050804 | modulation of chemical synaptic transmission | 47.6190 | 5 | yes |
GO:0051046 | regulation of secretion | 47.6190 | 5 | yes |
GO:0060627 | regulation of vesicle-mediated transport | 47.6190 | 4 | yes |
GO:0099177 | regulation of trans-synaptic signaling | 47.6190 | 4 | yes |
GO:1903530 | regulation of secretion by cell | 47.6190 | 4 | yes |
GO:0031323 | regulation of cellular metabolic process | 47.6190 | 4 | no |
GO:0006887 | exocytosis | 42.8571 | 4 | yes |
GO:0017157 | regulation of exocytosis | 38.0952 | 5 | yes |
GO:0023061 | signal release | 38.0952 | 4 | yes |
GO:0045055 | regulated exocytosis | 38.0952 | 5 | yes |
GO:0099003 | vesicle-mediated transport in synapse | 38.0952 | 5 | yes |
GO:0006996 | organelle organization | 38.0952 | 4 | no |
GO:0048523 | negative regulation of cellular process | 38.0952 | 4 | no |
GO:0051171 | regulation of nitrogen compound metabolic process | 38.0952 | 4 | no |
GO:0060255 | regulation of macromolecule metabolic process | 38.0952 | 4 | no |
GO:0080090 | regulation of primary metabolic process | 38.0952 | 4 | no |
GO:0032880 | regulation of protein localization | 33.3333 | 5 | no |
GO:0060341 | regulation of cellular localization | 33.3333 | 4 | no |
GO:0009893 | positive regulation of metabolic process | 33.3333 | 4 | no |
GO:0031325 | positive regulation of cellular metabolic process | 33.3333 | 5 | no |
GO:0043269 | regulation of ion transport | 33.3333 | 5 | no |
GO:0009306 | protein secretion | 28.5714 | 4 | yes |
GO:0010647 | positive regulation of cell communication | 28.5714 | 5 | yes |
GO:0016079 | synaptic vesicle exocytosis | 28.5714 | 4 | yes |
GO:0022603 | regulation of anatomical structure morphogenesis | 28.5714 | 4 | yes |
GO:0023056 | positive regulation of signaling | 28.5714 | 4 | yes |
GO:0035592 | establishment of protein localization to extracellular region | 28.5714 | 4 | yes |
GO:0071692 | protein localization to extracellular region | 28.5714 | 5 | yes |
GO:0099643 | signal release from synapse | 28.5714 | 5 | yes |
GO:0007268 | chemical synaptic transmission | 28.5714 | 6 | no |
GO:0022607 | cellular component assembly | 28.5714 | 4 | no |
GO:0031344 | regulation of cell projection organization | 28.5714 | 5 | no |
GO:0098916 | anterograde trans-synaptic signaling | 28.5714 | 5 | no |
GO:0099537 | trans-synaptic signaling | 28.5714 | 4 | no |
GO:0010604 | positive regulation of macromolecule metabolic process | 28.5714 | 5 | no |
GO:0019220 | regulation of phosphate metabolic process | 28.5714 | 6 | no |
GO:0031399 | regulation of protein modification process | 28.5714 | 6 | no |
GO:0043085 | positive regulation of catalytic activity | 28.5714 | 4 | no |
GO:0051173 | positive regulation of nitrogen compound metabolic process | 28.5714 | 5 | no |
GO:0051174 | regulation of phosphorus metabolic process | 28.5714 | 5 | no |
GO:0051246 | regulation of protein metabolic process | 28.5714 | 5 | no |
GO:0034762 | regulation of transmembrane transport | 28.5714 | 4 | no |
GO:0034765 | regulation of ion transmembrane transport | 28.5714 | 5 | no |
GO:1904062 | regulation of cation transmembrane transport | 28.5714 | 6 | no |
GO:0006886 | intracellular protein transport | 23.8095 | 4 | yes |
GO:0009966 | regulation of signal transduction | 23.8095 | 4 | yes |
GO:0017156 | calcium-ion regulated exocytosis | 23.8095 | 6 | yes |
GO:0010975 | regulation of neuron projection development | 23.8095 | 7 | no |
GO:0016050 | vesicle organization | 23.8095 | 5 | no |
GO:0048278 | vesicle docking | 23.8095 | 4 | no |
GO:0051223 | regulation of protein transport | 23.8095 | 5 | no |
GO:0070201 | regulation of establishment of protein localization | 23.8095 | 6 | no |
GO:0120035 | regulation of plasma membrane bounded cell projection organization | 23.8095 | 6 | no |
GO:0051130 | positive regulation of cellular component organization | 23.8095 | 5 | no |
GO:0001932 | regulation of protein phosphorylation | 23.8095 | 7 | no |
GO:0001934 | positive regulation of protein phosphorylation | 23.8095 | 8 | no |
GO:0009892 | negative regulation of metabolic process | 23.8095 | 4 | no |
GO:0010562 | positive regulation of phosphorus metabolic process | 23.8095 | 6 | no |
GO:0010605 | negative regulation of macromolecule metabolic process | 23.8095 | 5 | no |
GO:0031401 | positive regulation of protein modification process | 23.8095 | 7 | no |
GO:0042325 | regulation of phosphorylation | 23.8095 | 7 | no |
GO:0042327 | positive regulation of phosphorylation | 23.8095 | 8 | no |
GO:0045937 | positive regulation of phosphate metabolic process | 23.8095 | 7 | no |
GO:0051172 | negative regulation of nitrogen compound metabolic process | 23.8095 | 5 | no |
GO:0051247 | positive regulation of protein metabolic process | 23.8095 | 6 | no |
GO:0051248 | negative regulation of protein metabolic process | 23.8095 | 6 | no |
GO:0030030 | cell projection organization | 23.8095 | 4 | no |
GO:0010959 | regulation of metal ion transport | 23.8095 | 6 | no |
GO:0006836 | neurotransmitter transport | 19.0476 | 4 | yes |
GO:0009914 | hormone transport | 19.0476 | 4 | yes |
GO:0009967 | positive regulation of signal transduction | 19.0476 | 5 | yes |
GO:0022604 | regulation of cell morphogenesis | 19.0476 | 5 | yes |
GO:0044057 | regulation of system process | 19.0476 | 4 | yes |
GO:0046879 | hormone secretion | 19.0476 | 5 | yes |
GO:0048584 | positive regulation of response to stimulus | 19.0476 | 4 | yes |
GO:0050806 | positive regulation of synaptic transmission | 19.0476 | 5 | yes |
GO:0051094 | positive regulation of developmental process | 19.0476 | 4 | yes |
GO:0002790 | peptide secretion | 14.2857 | 5 | yes |
GO:0007269 | neurotransmitter secretion | 14.2857 | 4 | yes |
GO:0015833 | peptide transport | 14.2857 | 5 | yes |
GO:0030072 | peptide hormone secretion | 14.2857 | 6 | yes |
GO:0030073 | insulin secretion | 14.2857 | 5 | yes |
GO:0042886 | amide transport | 14.2857 | 5 | yes |
GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter | 14.2857 | 5 | yes |
GO:0001558 | regulation of cell growth | 9.5238 | 4 | yes |
GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 9.5238 | 4 | yes |
GO:0030307 | positive regulation of cell growth | 9.5238 | 5 | yes |
GO:0031644 | regulation of nervous system process | 9.5238 | 5 | yes |
GO:0045927 | positive regulation of growth | 9.5238 | 4 | yes |
GO:0048638 | regulation of developmental growth | 9.5238 | 4 | yes |
GO:0048639 | positive regulation of developmental growth | 9.5238 | 5 | yes |
GO:0051240 | positive regulation of multicellular organismal process | 9.5238 | 4 | yes |
GO:0098815 | modulation of excitatory postsynaptic potential | 9.5238 | 4 | yes |
GO:1903859 | regulation of dendrite extension | 9.5238 | 5 | yes |
GO:1903861 | positive regulation of dendrite extension | 9.5238 | 6 | yes |
GO:2000463 | positive regulation of excitatory postsynaptic potential | 9.5238 | 5 | yes |
Disease
No data found.
Uniprot ID | Details | Highest evidence | Localizing into PSD | HPA (protein expression in neurons) |
---|---|---|---|---|
RB6I2_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
1433F_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
UN13A_HUMAN | [view entry] [view interactions] | Low throughput | yes | no |
RPGF4_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAB3A_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
PCLO_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
RAB3C_HUMAN | [view entry] [view interactions] | Low throughput | yes | yes |
AP2B1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
FYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GRB2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
NCK1_HUMAN | [view interactions] | High throughput | no | yes |
DLG4_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
SRCN1_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
AGAP2_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
MYC_HUMAN | [view interactions] | High throughput | no | yes |
ESR2_HUMAN | [view interactions] | High throughput | no | no |
1433E_HUMAN | [view entry] [view interactions] | High throughput | yes | yes |
LYN_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
RAB3B_HUMAN | [view interactions] | High throughput | no | no |
RAB3D_HUMAN | [view interactions] | High throughput | no | yes |
RAB8A_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
GBRL1_HUMAN | [view interactions] | High throughput | no | yes |
MKRN2_HUMAN | [view interactions] | High throughput | no | yes |
RIMS3_HUMAN | [view entry] [view interactions] | High throughput | yes | no |
ARSB_HUMAN | [view interactions] | High throughput | no | yes |
MIPEP_HUMAN | [view interactions] | High throughput | no | yes |
XDH_HUMAN | [view interactions] | High throughput | no | no |
CAC1C_HUMAN | [view entry] [view interactions] | Computational | yes | no |
SNP25_HUMAN | [view entry] [view interactions] | Computational | yes | yes |
RIMB1_HUMAN | [view interactions] | Computational | no | yes |
RIMB2_HUMAN | [view entry] [view interactions] | Computational | yes | no |