Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RIMS3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Regulates synaptic membrane exocytosis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RIMS3_HUMAN
GO:0003723 RNA binding 50.0000 4 no
GO:0019900 kinase binding 40.0000 4 no
GO:0019901 protein kinase binding 40.0000 5 no
GO:0031267 small GTPase binding 30.0000 5 yes
GO:0051020 GTPase binding 30.0000 4 yes
GO:0045309 protein phosphorylated amino acid binding 30.0000 4 no
GO:0050815 phosphoserine residue binding 30.0000 5 no
GO:0043169 cation binding 30.0000 4 no
GO:0046872 metal ion binding 30.0000 5 no

Biological process

Term Name % Distance from top the of the tree Annotated in RIMS3_HUMAN
GO:0010646 regulation of cell communication 80.0000 4 yes
GO:0048522 positive regulation of cellular process 80.0000 4 yes
GO:0050804 modulation of chemical synaptic transmission 60.0000 5 yes
GO:0051049 regulation of transport 60.0000 4 yes
GO:0099177 regulation of trans-synaptic signaling 60.0000 4 yes
GO:0008104 protein localization 60.0000 4 no
GO:0031323 regulation of cellular metabolic process 60.0000 4 no
GO:0048523 negative regulation of cellular process 60.0000 4 no
GO:0060255 regulation of macromolecule metabolic process 60.0000 4 no
GO:0051046 regulation of secretion 50.0000 5 yes
GO:0060627 regulation of vesicle-mediated transport 50.0000 4 yes
GO:1903530 regulation of secretion by cell 50.0000 4 yes
GO:0048584 positive regulation of response to stimulus 50.0000 4 no
GO:0009966 regulation of signal transduction 50.0000 4 no
GO:0051128 regulation of cellular component organization 50.0000 4 no
GO:0071702 organic substance transport 50.0000 4 no
GO:0071705 nitrogen compound transport 50.0000 4 no
GO:0010647 positive regulation of cell communication 40.0000 5 yes
GO:0017157 regulation of exocytosis 40.0000 5 yes
GO:0023056 positive regulation of signaling 40.0000 4 yes
GO:0046903 secretion 40.0000 4 yes
GO:0046928 regulation of neurotransmitter secretion 40.0000 5 yes
GO:0051588 regulation of neurotransmitter transport 40.0000 5 yes
GO:1903305 regulation of regulated secretory pathway 40.0000 6 yes
GO:2000300 regulation of synaptic vesicle exocytosis 40.0000 6 yes
GO:0032880 regulation of protein localization 40.0000 5 no
GO:0060341 regulation of cellular localization 40.0000 4 no
GO:0080090 regulation of primary metabolic process 40.0000 4 no
GO:0009889 regulation of biosynthetic process 40.0000 4 no
GO:0010468 regulation of gene expression 40.0000 6 no
GO:0010556 regulation of macromolecule biosynthetic process 40.0000 5 no
GO:0031326 regulation of cellular biosynthetic process 40.0000 5 no
GO:0015031 protein transport 40.0000 4 no
GO:0016079 synaptic vesicle exocytosis 30.0000 4 yes
GO:0017156 calcium-ion regulated exocytosis 30.0000 5 yes
GO:0023061 signal release 30.0000 4 yes
GO:0045055 regulated exocytosis 30.0000 4 yes
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 30.0000 5 yes
GO:0050806 positive regulation of synaptic transmission 30.0000 5 yes
GO:0099643 signal release from synapse 30.0000 5 yes
GO:0009892 negative regulation of metabolic process 30.0000 4 no
GO:0010605 negative regulation of macromolecule metabolic process 30.0000 5 no
GO:0031324 negative regulation of cellular metabolic process 30.0000 5 no
GO:0044057 regulation of system process 30.0000 4 no
GO:0050776 regulation of immune response 30.0000 4 no
GO:0051246 regulation of protein metabolic process 30.0000 5 no
GO:0006796 phosphate-containing compound metabolic process 30.0000 4 no
GO:0009267 cellular response to starvation 30.0000 4 no
GO:0010648 negative regulation of cell communication 30.0000 5 no
GO:0023057 negative regulation of signaling 30.0000 4 no
GO:0036211 protein modification process 30.0000 4 no
GO:0042149 cellular response to glucose starvation 30.0000 5 no
GO:0043412 macromolecule modification 30.0000 4 no
GO:1902531 regulation of intracellular signal transduction 30.0000 5 no
GO:0006886 intracellular protein transport 30.0000 4 no
GO:0030030 cell projection organization 30.0000 4 no
GO:0009967 positive regulation of signal transduction 30.0000 5 no
GO:0071310 cellular response to organic substance 30.0000 4 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CACB4_HUMAN [view entry] [view interactions] Low throughput yes yes
CREB3_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
CXA5_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
PECA1_HUMAN [view interactions] High throughput no no
VIME_HUMAN [view entry] [view interactions] High throughput yes no
KAT5_HUMAN [view interactions] High throughput no yes
ZDH17_HUMAN [view entry] [view interactions] High throughput yes yes
TRI54_HUMAN [view interactions] High throughput no no
BANP_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
RIMS2_HUMAN [view entry] [view interactions] High throughput yes no
POTEF_HUMAN [view interactions] High throughput no no