Features Interactions Isoform Disease Linear motifs Fingerprint Network All partners

RIMS3_HUMAN

Evidence for PS localization

GO
G2C
SynGO
SynaptomeDB

Functions

Regulates synaptic membrane exocytosis. [View more on UniProt]

Protein features

Binary interactions with known binding regions

Interacting region for partners were not defined.

Network

Download full PS network for entry.

Isoforms

Disease-causing germline mutations

No data found.

Linear motifs

No annotated instance was found. To search for linear motifs, use the ELM prediction server.

Fingerprint

Molecular function

Term Name % Distance from the top of the tree Annotated in RIMS3_HUMAN
GO:0003723 RNA binding 55.5556 4 no
GO:0031267 small GTPase binding 33.3333 5 yes
GO:0051020 GTPase binding 33.3333 4 yes
GO:0046872 metal ion binding 33.3333 4 no
GO:0019900 kinase binding 33.3333 4 no
GO:0019901 protein kinase binding 33.3333 5 no
GO:0031625 ubiquitin protein ligase binding 22.2222 5 no
GO:0044389 ubiquitin-like protein ligase binding 22.2222 4 no
GO:0045296 cadherin binding 22.2222 4 no
GO:0005080 protein kinase C binding 22.2222 6 no

Biological process

Term Name % Distance from top the of the tree Annotated in RIMS3_HUMAN
GO:0010646 regulation of cell communication 66.6667 4 yes
GO:0048522 positive regulation of cellular process 66.6667 4 yes
GO:0051049 regulation of transport 66.6667 4 yes
GO:0006886 intracellular protein transport 66.6667 4 no
GO:0008104 protein localization 66.6667 4 no
GO:0015031 protein transport 66.6667 4 no
GO:0071702 organic substance transport 66.6667 4 no
GO:0071705 nitrogen compound transport 66.6667 4 no
GO:0050804 modulation of chemical synaptic transmission 55.5556 5 yes
GO:0099177 regulation of trans-synaptic signaling 55.5556 4 yes
GO:0051128 regulation of cellular component organization 55.5556 4 no
GO:0060255 regulation of macromolecule metabolic process 55.5556 4 no
GO:0048523 negative regulation of cellular process 55.5556 4 no
GO:0016192 vesicle-mediated transport 44.4444 4 yes
GO:0051046 regulation of secretion 44.4444 5 yes
GO:1903530 regulation of secretion by cell 44.4444 4 yes
GO:0009966 regulation of signal transduction 44.4444 4 no
GO:0031323 regulation of cellular metabolic process 44.4444 4 no
GO:0051171 regulation of nitrogen compound metabolic process 44.4444 4 no
GO:0080090 regulation of primary metabolic process 44.4444 4 no
GO:0031324 negative regulation of cellular metabolic process 33.3333 5 no
GO:0051172 negative regulation of nitrogen compound metabolic process 33.3333 5 no
GO:0006887 exocytosis 33.3333 4 yes
GO:0010647 positive regulation of cell communication 33.3333 5 yes
GO:0016079 synaptic vesicle exocytosis 33.3333 4 yes
GO:0017156 calcium-ion regulated exocytosis 33.3333 6 yes
GO:0023056 positive regulation of signaling 33.3333 4 yes
GO:0023061 signal release 33.3333 4 yes
GO:0045055 regulated exocytosis 33.3333 5 yes
GO:0046903 secretion 33.3333 4 yes
GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 33.3333 5 yes
GO:0050806 positive regulation of synaptic transmission 33.3333 5 yes
GO:0060627 regulation of vesicle-mediated transport 33.3333 4 yes
GO:0099003 vesicle-mediated transport in synapse 33.3333 5 yes
GO:0099643 signal release from synapse 33.3333 5 yes
GO:0010468 regulation of gene expression 33.3333 5 no
GO:0044057 regulation of system process 33.3333 4 no
GO:0051246 regulation of protein metabolic process 33.3333 5 no
GO:0006605 protein targeting 33.3333 5 no
GO:0009892 negative regulation of metabolic process 33.3333 4 no
GO:0010605 negative regulation of macromolecule metabolic process 33.3333 5 no
GO:0022898 regulation of transmembrane transporter activity 22.2222 4 no
GO:0031399 regulation of protein modification process 22.2222 6 no
GO:0031400 negative regulation of protein modification process 22.2222 7 no
GO:0032412 regulation of ion transmembrane transporter activity 22.2222 5 no
GO:0032880 regulation of protein localization 22.2222 5 no
GO:0034762 regulation of transmembrane transport 22.2222 4 no
GO:0034765 regulation of ion transmembrane transport 22.2222 5 no
GO:0043269 regulation of ion transport 22.2222 5 no
GO:0045936 negative regulation of phosphate metabolic process 22.2222 7 no
GO:0051050 positive regulation of transport 22.2222 4 no
GO:0051174 regulation of phosphorus metabolic process 22.2222 5 no
GO:0051223 regulation of protein transport 22.2222 5 no
GO:0051248 negative regulation of protein metabolic process 22.2222 6 no
GO:0051924 regulation of calcium ion transport 22.2222 7 no
GO:0060341 regulation of cellular localization 22.2222 4 no
GO:0070201 regulation of establishment of protein localization 22.2222 6 no
GO:1901019 regulation of calcium ion transmembrane transporter activity 22.2222 6 no
GO:1903169 regulation of calcium ion transmembrane transport 22.2222 7 no
GO:1904062 regulation of cation transmembrane transport 22.2222 6 no
GO:0006468 protein phosphorylation 22.2222 5 no
GO:0006796 phosphate-containing compound metabolic process 22.2222 4 no
GO:0016310 phosphorylation 22.2222 5 no
GO:0036211 protein modification process 22.2222 4 no
GO:0043412 macromolecule modification 22.2222 4 no
GO:0017157 regulation of exocytosis 22.2222 5 yes
GO:0046928 regulation of neurotransmitter secretion 22.2222 4 yes
GO:0051588 regulation of neurotransmitter transport 22.2222 5 yes
GO:0001558 regulation of cell growth 22.2222 4 no
GO:0009893 positive regulation of metabolic process 22.2222 4 no
GO:0009967 positive regulation of signal transduction 22.2222 5 no
GO:0010604 positive regulation of macromolecule metabolic process 22.2222 5 no
GO:0010628 positive regulation of gene expression 22.2222 6 no
GO:0022603 regulation of anatomical structure morphogenesis 22.2222 4 no
GO:0022604 regulation of cell morphogenesis 22.2222 5 no
GO:0022607 cellular component assembly 22.2222 4 no
GO:0030307 positive regulation of cell growth 22.2222 5 no
GO:0031644 regulation of nervous system process 22.2222 5 no
GO:0031646 positive regulation of nervous system process 22.2222 5 no
GO:0045927 positive regulation of growth 22.2222 4 no
GO:0048584 positive regulation of response to stimulus 22.2222 4 no
GO:0048638 regulation of developmental growth 22.2222 4 no
GO:0048639 positive regulation of developmental growth 22.2222 5 no
GO:0051094 positive regulation of developmental process 22.2222 4 no
GO:0051240 positive regulation of multicellular organismal process 22.2222 4 no
GO:0061024 membrane organization 22.2222 4 no
GO:0097151 positive regulation of inhibitory postsynaptic potential 22.2222 5 no
GO:0098815 modulation of excitatory postsynaptic potential 22.2222 4 no
GO:0098828 modulation of inhibitory postsynaptic potential 22.2222 4 no
GO:1903859 regulation of dendrite extension 22.2222 5 no
GO:1903861 positive regulation of dendrite extension 22.2222 6 no
GO:2000463 positive regulation of excitatory postsynaptic potential 22.2222 5 no
GO:0006996 organelle organization 22.2222 4 no
GO:0009889 regulation of biosynthetic process 22.2222 4 no
GO:0010243 response to organonitrogen compound 22.2222 4 no
GO:0010556 regulation of macromolecule biosynthetic process 22.2222 5 no
GO:0019219 regulation of nucleobase-containing compound metabolic process 22.2222 5 no
GO:0021782 glial cell development 22.2222 4 no
GO:0031326 regulation of cellular biosynthetic process 22.2222 5 no
GO:0051129 negative regulation of cellular component organization 22.2222 5 no
GO:0051252 regulation of RNA metabolic process 22.2222 5 no
GO:0071310 cellular response to organic substance 22.2222 4 no
GO:0071417 cellular response to organonitrogen compound 22.2222 4 no
GO:1901652 response to peptide 22.2222 4 no
GO:1901653 cellular response to peptide 22.2222 5 no
GO:1901699 cellular response to nitrogen compound 22.2222 4 no
GO:1901701 cellular response to oxygen-containing compound 22.2222 4 no
GO:0000165 MAPK cascade 22.2222 4 no
GO:0010563 negative regulation of phosphorus metabolic process 22.2222 6 no
GO:0010959 regulation of metal ion transport 22.2222 6 no
GO:0019220 regulation of phosphate metabolic process 22.2222 6 no

Disease

No data found.

All partners

Uniprot ID Details Highest evidence Localizing into PSD HPA (protein expression in neurons)
CACB4_HUMAN [view entry] [view interactions] Low throughput yes yes
CREB3_HUMAN [view interactions] High throughput no no
1433G_HUMAN [view entry] [view interactions] High throughput yes yes
CXA5_HUMAN [view interactions] High throughput no yes
PICK1_HUMAN [view entry] [view interactions] High throughput yes yes
PECA1_HUMAN [view interactions] High throughput no no
VIME_HUMAN [view entry] [view interactions] High throughput yes no
KAT5_HUMAN [view interactions] High throughput no yes
ZDH17_HUMAN [view interactions] High throughput no yes
TRI54_HUMAN [view interactions] High throughput no no
BANP_HUMAN [view interactions] High throughput no yes
MEOX2_HUMAN [view interactions] High throughput no no
1433E_HUMAN [view entry] [view interactions] High throughput yes yes
1433Z_HUMAN [view entry] [view interactions] High throughput yes yes
RIMS1_HUMAN [view entry] [view interactions] High throughput yes yes
RIMS2_HUMAN [view entry] [view interactions] High throughput yes no
POTEF_HUMAN [view interactions] High throughput no no